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The universe.
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Vast, dynamic and explosive.
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But this huge cosmos
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with its billions of galaxies
and countless stars
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isn't the only one.
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We share our lives
with another universe.
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The world of the small,
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of the viruses,
of the bacteria.
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We call this strange hidden kingdom
the microcosmos.
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The microcosmos
is incredibly important.
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Even though we can't see it,
it's everywhere.
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It's almost like another universe
or another world, all in its own.
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It guided our evolution.
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We wouldn't be here
without the microcosmos.
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And it keeps us alive.
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The microcosmos is responsible for
the very oxygen that we breathe.
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And it will influence our future
as we venture out into space.
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If we were ever to find a place
where there is life,
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potentially a new microcosmos,
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we would have no immunity
if they're bad.
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We share our world
with the microcosmos.
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Will we coexist
in an uneasy peace...
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..or will it destroy us?
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A strange, invisible assassin
stalks its prey.
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It attacks and hijacks the cell,
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forcing it to produce
hundreds of new raiders.
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This is what happens
when the microcosmos turns on us.
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In 2020, we experienced
this invasion of the body snatchers
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first hand.
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A tiny virus
caused a global pandemic.
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Covid-19.
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This pandemic makes me see the world
completely differently,
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because there was
an invisible universe,
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one that covers me and is within me,
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that I pretty much ignored
for the most part.
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Maybe we ignore this other universe
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because it's invisible
to the naked eye.
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We live in a largely
invisible universe.
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We can't see everything
that's going on.
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Some of the bigger stuff,
we can't see very well,
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and, in fact, a lot of
the littlest stuff we can't either.
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Just because something is too small
to see
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doesn't mean it's not important.
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In fact, very, very tiny things
have a huge impact on our lives.
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Some of these impacts
are beneficial,
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but they're overshadowed by
the devastating effects of disease.
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The longest-running conflict
that humanity has been engaged in
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is that against the microcosmos.
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Our long-running battle
against the bacteria and viruses
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that are trying to kill us.
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00:02:58,800 --> 00:03:02,760
A century ago,
we faced the Spanish flu.
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This absolutely annihilated Europe
at the time.
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It caused million upon millions
of deaths.
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So this is definitely not
the first pandemic.
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It quite frankly
probably isn't the last one.
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In a way, the coronavirus
has forced us
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to come to a greater understanding
of the microscopic world.
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The microcosmos is complex.
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While some parts kill us,
others keep us alive.
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The microcosmos is important
for us to survive,
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in order for us to do all of
the things that our body does,
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in order for us to live and grow
and thrive.
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Our lives depend on the microcosmos.
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The air we breathe
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and the surface of the Earth
around us
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has been profoundly affected
by the microcosmos.
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The invisible microcosmos operates
in every part of the world.
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This world that you can't see
is everywhere.
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From geothermal hot springs
to glaciers,
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to deep sea hydrothermal
vent systems.
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We have discovered that every
cubic foot of Earth's atmosphere
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and its oceans
contain millions of viruses.
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There are more viruses here on Earth
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than there are stars
in the universe.
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That's incredible.
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Even though they're around one 400th
the thickness of human hair,
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stuck end to end,
all the viruses on Earth
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would stretch
100 million light years.
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That's 40 times the distance
to our neighbouring galaxy,
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Andromeda.
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That really makes us ask,
whose planet is this anyway?
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If you just added this up
by sheer numbers,
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you would say
this is the virus planet.
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The microcosmos
has also taken over our bodies.
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We're only partly human.
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The fact that so little of
my own body, of everyone's body,
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is human cells
kinda leaves you wondering
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what's the rest of it made of,
right?
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It is astonishing that
we share our bodies
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with over 380 trillion viruses.
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And over 39 trillion
bacterial cells.
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The average human
has more bacterial cells
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inside their body
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than their are human cells
inside their body.
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So, what are we really?
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There are moments
in the history of science
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that I actually remember
where I was when they happened,
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when, for example, we detected
two colliding black holes
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or something like that.
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But another one was when I realised
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that almost half our body
is actually not human.
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I mean, that is crazy.
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For people that are scared of
bacteria,
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that's a really interesting thing
to know, right?
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Bacteria help us digest food,
produce vitamins,
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and even influence our mood.
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But what are they?
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Bacteria are single-celled organisms
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with a cell wall
and a central nucleus
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containing genetic material,
RNA or DNA.
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They can move around and replicate.
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Viruses are completely different.
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In the universe,
there are some mysteries
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that have actually personally
made me kind of pause
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and given me goosebumps.
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And strangely enough,
one of them is viruses.
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The mystery is how viruses can have
so much impact on the world,
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despite their tiny size
and apparent simplicity.
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Most are just a strand of
genetic material,
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sometimes encased
in a shell of protein.
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Compared to bacteria,
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which behave kind of like
other normal cells
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that we're used to to some degree,
viruses are very strange.
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We don't really understand viruses.
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We don't even know if they're alive
or not.
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The question are viruses alive
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is actually more difficult to answer
than you might think.
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What is the definition of life?
What does it mean to be alive?
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NASA's definition of life
is a self-sustained chemical system
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capable of Darwinian evolution.
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Entities that feed, make energy
and reproduce.
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Viruses can't do that on their own.
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They have to have a host cell
to do that.
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They have the genetic material
that they need,
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but none of the machinery.
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So they really have to infect
a host.
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If not, they're useless.
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Inside a host's body,
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viruses latch on to
the surface of cells...
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..and then take control.
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A virus's life cycle is effectively
to hack another cell.
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They have to inject
that genetic material
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into a living cell.
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And then the cell is hijacked
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and starts making copies of
the virus.
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Which then have to burst
out of this cell,
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almost literally like that gory,
grotesque scene in Aliens.
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They burst out from the inside.
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That's like a sailor level
horror movie.
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This method of replicating
is chilling.
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It doesn't answer the question of
whether they're alive.
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That uncertainty may influence
our search for life in space.
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One of the interesting things
to think about
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is if we found a virus
on another planetary surface,
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would we classify that as life?
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Would we say that we have found
life?
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We don't know.
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But space viruses could be a sign of
other extra-terrestrial life forms.
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Viruses have to have a host cell
to replicate.
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So if you find a virus,
in essence, you've found life.
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Viruses might lead us
to extra-terrestrial life.
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Now, new research suggests
that life on Earth
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may have come from space,
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brought to us
in a cosmic bombardment
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when our planet was young.
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We find the microcosmos
in every feature of Earth.
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But where did this strange kingdom
of the very small come from?
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Some of its members are so weird
they look like aliens.
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Could they have come from space?
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There's this idea that microbes
could have hitched a ride
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on a chunk of an asteroid
that would fall to Earth.
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They could form
on a different planet,
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something hits that planet,
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the rock that they're sitting on
gets lifted,
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and then hits the Earth
as a meteorite.
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The idea of hitchhiking bugs
sounds a bit wild.
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But we have found chunks of Mars
on Earth.
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Perhaps these space rocks
brought life.
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It's not completely ridiculous.
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We know that rocks, for example,
could come form Mars
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and land on Earth.
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A giant asteroid impact on Mars
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could blow shrapnel into space
that could land on Earth.
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To learn how, we must return to
the early solar system,
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4.5 billion years ago.
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Many infant planets
orbit a new star, our sun.
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This infant solar system is chaotic.
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Collisions between planets
are inevitable.
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The early solar system
was like a pinball machine.
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Stuff was hitting,
knocking stuff off,
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that would land somewhere
and knock stuff off.
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The young Mars
is in the line of fire.
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It already has primitive oceans
and perhaps primitive life.
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A huge space rock
smashes into the surface.
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We call the event
the Borealis Impact.
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It blows quadrillion tons of rock
into space.
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It's not crazy to think that
one of these chunks of rock
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travelling through our solar system
had some hitchhikers on board.
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If there's some microbe
riding on an asteroid
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that got blasted off of Mars,
I kinda feel sorry for it, right?
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It's just living there on Mars
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doing whatever
little Martian microbes do
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and then a giant impact
ejects this thing into space.
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00:11:05,160 --> 00:11:09,440
In order to get from one planet
to another,
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a cell would have to run a gauntlet.
206
00:11:12,760 --> 00:11:16,520
It's almost like winning
a survival game show.
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You've got to survive
being blasted off your home world.
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You've then got to survive
the interplanetary journey
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inside a small lump of rock,
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00:11:26,680 --> 00:11:29,680
being exposed to
the vacuum of outer space,
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to cosmic rays, to UV radiation,
being dried out and frozen.
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So the idea of moving life around
the solar system
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or around the galaxy on asteroids
poses a lot of different challenges.
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00:11:44,400 --> 00:11:48,720
Events like the Borealis Impact
ejected so much rock from Mars,
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there were lots of opportunities
for hitchhiking bugs
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to run the gauntlet of space.
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But could they survive the journey?
218
00:11:58,200 --> 00:12:01,840
To find out, astronauts
on the International Space Station
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grew simple bacteria
outside in space.
220
00:12:07,800 --> 00:12:11,960
After a year of being in open space,
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miraculously some of these microbes
survived.
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It's incredible.
223
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These microbes
just could not be killed,
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even though they were in
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the worst possible environment
for life.
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The mission, therefore, shows us
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that life can survive
the environment in outer space.
228
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Life could be transferred
between planets.
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00:12:33,960 --> 00:12:38,280
Maybe life did get started on Mars,
on our next-door neighbour planet,
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00:12:38,360 --> 00:12:42,440
and then was transferred here
inside a meteorite.
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00:12:42,520 --> 00:12:45,880
Maybe we are immigrants from Mars.
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Hitchhiking bugs
may have arrived on Earth
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and kickstarted the microcosmos.
234
00:12:52,480 --> 00:12:55,360
But now,
recent studies of meteorites
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suggest that even if living microbes
didn't make the journey,
236
00:12:59,600 --> 00:13:02,800
the building blocks that made them
did.
237
00:13:04,400 --> 00:13:08,040
In November 2019,
an international research team
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00:13:08,120 --> 00:13:10,760
found an organic molecule
called ribose
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in meteorites that had crashed
on Earth.
240
00:13:14,360 --> 00:13:17,320
Ribose is a sugar.
241
00:13:17,400 --> 00:13:19,040
It's a simple sugar,
242
00:13:19,120 --> 00:13:23,280
but it is a sugar
that is absolutely crucial
243
00:13:23,360 --> 00:13:26,160
to all life on Earth.
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00:13:26,240 --> 00:13:29,960
Ribose is the sugar
that makes up RNA,
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00:13:30,040 --> 00:13:35,480
and RNA sits right in the lynchpin
of every cell.
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00:13:36,520 --> 00:13:39,240
RNA is a simple form of
genetic material
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that controls cellular function.
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00:13:41,960 --> 00:13:45,120
It's found in
most primitive creatures.
249
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Finding ribose on a meteorite
250
00:13:48,280 --> 00:13:53,120
is so important for us to understand
the origins of the microcosmos,
251
00:13:53,200 --> 00:13:55,000
because these are
the building blocks.
252
00:13:55,080 --> 00:13:58,320
These are the things that it needs
to get started.
253
00:13:58,400 --> 00:14:02,160
So understanding where
these building blocks come from
254
00:14:02,240 --> 00:14:05,040
allows us to understand
255
00:14:05,120 --> 00:14:09,000
how the microcosmos
might have evolved and started.
256
00:14:10,400 --> 00:14:11,480
The Rosetta Mission
257
00:14:11,560 --> 00:14:15,200
found another building block
for life out in space.
258
00:14:15,280 --> 00:14:18,600
A form of phosphorous
on the comet 67P.
259
00:14:19,640 --> 00:14:20,800
This was astounding.
260
00:14:20,880 --> 00:14:25,120
- Comet 67
- P was formed
at the birth of the solar system,
261
00:14:25,200 --> 00:14:27,440
4.67 billion years ago.
262
00:14:27,520 --> 00:14:29,520
And it hasn't changed since then.
263
00:14:29,600 --> 00:14:33,800
It's a time capsule from the birth
of the sun and the planets.
264
00:14:33,880 --> 00:14:37,040
And it's been in the deep freeze
ever since.
265
00:14:37,120 --> 00:14:41,440
So these forms of phosphorous
that we found on comet 67P
266
00:14:41,520 --> 00:14:45,400
tell us what was available
at the time the Earth was forming
267
00:14:45,480 --> 00:14:49,680
and then when life was getting
started on primordial Earth.
268
00:14:50,720 --> 00:14:53,200
The early solar system
contained many chemicals
269
00:14:53,280 --> 00:14:54,360
needed for life.
270
00:14:55,560 --> 00:14:56,880
It's an important discovery
271
00:14:56,960 --> 00:14:59,520
because it means that these
compounds were around
272
00:14:59,600 --> 00:15:01,480
when the solar system was forming.
273
00:15:01,560 --> 00:15:03,440
So they would have been
readily available
274
00:15:03,520 --> 00:15:07,960
for life to tap into and use
to start forming cellular structure.
275
00:15:09,160 --> 00:15:13,560
These discoveries not only show that
essential chemicals came to Earth,
276
00:15:13,640 --> 00:15:16,520
but that they exist
throughout the solar system.
277
00:15:17,560 --> 00:15:21,040
We tend to think of the microcosmos
as only existing on Earth,
278
00:15:21,120 --> 00:15:23,760
in the sense that only Earth
has these building blocks.
279
00:15:23,840 --> 00:15:27,840
But now these new observations
suggest that a microcosmos,
280
00:15:27,920 --> 00:15:29,640
at least the building blocks
for one,
281
00:15:29,720 --> 00:15:33,320
could exist beyond Earth
and throughout the solar system.
282
00:15:35,640 --> 00:15:36,640
We got evidence
283
00:15:36,720 --> 00:15:41,360
for the widespread distribution of
these building blocks in 2017.
284
00:15:42,880 --> 00:15:48,000
A strange space rock called Oumuamua
raced through the solar system.
285
00:15:49,080 --> 00:15:51,320
The weird thing about Oumuamua
286
00:15:51,400 --> 00:15:56,360
is that it's clearly on a trajectory
that came from deep space,
287
00:15:56,440 --> 00:15:58,000
interstellar space.
288
00:15:58,080 --> 00:16:00,840
That it literally came from
another star.
289
00:16:01,880 --> 00:16:05,120
Even weirder, its colour.
Its surface is red.
290
00:16:06,160 --> 00:16:08,120
And so that raised
a lot of questions
291
00:16:08,200 --> 00:16:09,920
about what its composition could be.
292
00:16:10,000 --> 00:16:11,800
And one possibility
293
00:16:11,880 --> 00:16:14,960
is that it's actually filled with
organic materials
294
00:16:15,040 --> 00:16:16,760
which tend to have those colours,
295
00:16:16,840 --> 00:16:19,520
especially when exposed to
the space environment.
296
00:16:19,600 --> 00:16:22,240
This suggests organic materials
297
00:16:22,320 --> 00:16:25,120
may travel through
interstellar space.
298
00:16:25,200 --> 00:16:27,000
I think it's entirely reasonable
299
00:16:27,080 --> 00:16:29,800
that we could be getting
organic materials
300
00:16:29,880 --> 00:16:33,720
that are the building blocks of life
from outside of our solar system.
301
00:16:33,800 --> 00:16:36,960
There may be
a molecular transport system
302
00:16:37,040 --> 00:16:38,600
throughout the galaxy.
303
00:16:38,680 --> 00:16:40,160
We could be receiving stuff
304
00:16:40,240 --> 00:16:42,640
from other bodies
in our solar system
305
00:16:42,720 --> 00:16:44,920
and from bodies
outside our solar system,
306
00:16:45,000 --> 00:16:47,400
because stuff is moving around.
307
00:16:47,480 --> 00:16:49,840
Oumuamua is just
the tip of the iceberg.
308
00:16:49,920 --> 00:16:52,640
There are probably
lots of interstellar visitors
309
00:16:52,720 --> 00:16:54,800
passing through our solar system
all the time.
310
00:16:56,000 --> 00:16:58,640
Comets and asteroids
may have brought chemicals
311
00:16:58,720 --> 00:17:00,560
to kickstart the microcosmos.
312
00:17:03,240 --> 00:17:07,960
Now, explosive new research suggests
that space rocks hitting Earth
313
00:17:08,040 --> 00:17:09,200
did even more.
314
00:17:10,280 --> 00:17:14,760
Could the violent impacts themselves
have helped life get started.
315
00:17:25,400 --> 00:17:29,640
How did the microcosmos
and life on Earth start?
316
00:17:29,720 --> 00:17:32,760
Did asteroids and comets
deliver the building blocks,
317
00:17:33,880 --> 00:17:37,200
phosphorous, ribose
and other organic compounds?
318
00:17:37,280 --> 00:17:39,840
Or did they start life
in other ways?
319
00:17:39,920 --> 00:17:44,400
New research suggests
the impact of crashing space rocks
320
00:17:44,480 --> 00:17:46,680
could have provided
the spark for life.
321
00:17:47,760 --> 00:17:49,000
The force of the impact
322
00:17:49,080 --> 00:17:52,400
actually triggered the creation of
these molecules
323
00:17:52,480 --> 00:17:54,480
that are the building blocks of
life.
324
00:17:58,560 --> 00:18:02,720
The energy from the impact
breaks down and reforms molecules
325
00:18:02,800 --> 00:18:04,520
into new compounds.
326
00:18:04,600 --> 00:18:07,160
You can actually strip apart atoms
and molecules,
327
00:18:07,240 --> 00:18:09,240
recombine them in more complex ways,
328
00:18:09,320 --> 00:18:12,360
and make the stuff of life
in an impact.
329
00:18:13,400 --> 00:18:14,720
Over millions of years,
330
00:18:14,800 --> 00:18:18,200
complex organic materials
fill Earth's oceans.
331
00:18:19,280 --> 00:18:22,440
Then, around 3.5 billion years ago,
332
00:18:22,520 --> 00:18:25,320
the process that kickstarted life
began.
333
00:18:26,760 --> 00:18:30,640
Going back to the origins of life
on Earth, it was a process.
334
00:18:30,720 --> 00:18:32,440
You began with large molecules
335
00:18:32,520 --> 00:18:36,080
that almost accidentally
began to make copies of themselves.
336
00:18:36,160 --> 00:18:38,520
These became
the first genetic material.
337
00:18:38,600 --> 00:18:41,360
Some of these larger molecules
bound together
338
00:18:41,440 --> 00:18:44,000
and became the first
sort of protocells.
339
00:18:44,080 --> 00:18:47,240
A protocell could represent
340
00:18:47,320 --> 00:18:52,840
this earliest
pre-life stage of evolution.
341
00:18:54,640 --> 00:18:59,440
Protocells lack the full
chemical machinery of modern cells.
342
00:18:59,520 --> 00:19:01,320
They're a simple cell membrane,
343
00:19:01,400 --> 00:19:05,360
surrounding a glob of
genetic material like RNA,
344
00:19:05,440 --> 00:19:07,760
built from ribose and phosphorous.
345
00:19:08,800 --> 00:19:10,600
Now you have a barrier.
346
00:19:10,680 --> 00:19:13,680
Now you can actually control
which chemicals come into the cell
347
00:19:13,760 --> 00:19:14,760
and which go out,
348
00:19:14,840 --> 00:19:19,600
and you protect the genetic code
intact inside the cell.
349
00:19:19,680 --> 00:19:23,640
Once that happened,
evolution began to run with it.
350
00:19:23,720 --> 00:19:27,640
These simple cells
grew more and more complicated,
351
00:19:27,720 --> 00:19:32,720
until, shazam,
you get all life on Earth.
352
00:19:32,800 --> 00:19:35,440
All cellular life anyway.
353
00:19:35,520 --> 00:19:40,080
Unlike bacteria,
viruses are not cells,
354
00:19:40,160 --> 00:19:43,720
Scientists debate
if they are even living things.
355
00:19:43,800 --> 00:19:47,200
So, how then do viruses
fit into the birth of life?
356
00:19:47,280 --> 00:19:49,840
Viruses aren't really thought of
357
00:19:49,920 --> 00:19:52,480
as playing a role
in our evolutionary history,
358
00:19:52,560 --> 00:19:54,440
but we're just beginning
to understand
359
00:19:54,520 --> 00:19:56,200
that that's simply not the case.
360
00:19:56,280 --> 00:19:58,080
What if viruses themselves
361
00:19:58,160 --> 00:20:00,960
were an essential cog
in the machinery of life?
362
00:20:02,040 --> 00:20:06,480
How can we investigate if viruses
helped life on Earth develop?
363
00:20:06,560 --> 00:20:09,080
They don't leave many clues
about their past.
364
00:20:10,360 --> 00:20:15,240
The hard thing with understanding
the evolutionary history of viruses
365
00:20:15,320 --> 00:20:17,200
is they don't leave a fossil record.
366
00:20:17,280 --> 00:20:20,680
There's no geology
that we can go back and dig up,
367
00:20:20,760 --> 00:20:24,240
and say, "Aha! This is when viruses
first came about."
368
00:20:25,880 --> 00:20:30,280
We don't know when viruses entered
the evolutionary game of life.
369
00:20:31,480 --> 00:20:34,720
Was it near the beginning
or a little bit later?
370
00:20:34,800 --> 00:20:37,600
There is this crazy idea
that viruses
371
00:20:37,680 --> 00:20:40,280
might actually have come first
in the tree of life.
372
00:20:40,360 --> 00:20:43,000
When you think about
the real origins of life,
373
00:20:43,080 --> 00:20:45,480
it had to start with something
that simple.
374
00:20:45,560 --> 00:20:48,880
Something that was just a molecule
that could start replicating.
375
00:20:48,960 --> 00:20:52,760
A virus may be our best example of
that transition
376
00:20:52,840 --> 00:20:56,160
from just complex chemistry
to the beginnings of life.
377
00:20:57,200 --> 00:20:59,520
In this scenario, chemicals floating
378
00:20:59,600 --> 00:21:02,160
in the three-and-a-half
billion year old oceans
379
00:21:02,240 --> 00:21:06,040
formed a shell of protein
around some simple genetic material.
380
00:21:07,480 --> 00:21:11,800
But did viruses evolve
before anything else?
381
00:21:11,880 --> 00:21:15,600
The flaw
in the virus first hypothesis
382
00:21:15,680 --> 00:21:20,680
is that a virus has to have
a host organism to replicate.
383
00:21:20,760 --> 00:21:24,560
So, without a host,
how does the virus replicate?
384
00:21:24,640 --> 00:21:27,280
And this is the question
we have to ask ourselves
385
00:21:27,360 --> 00:21:30,880
when we think of viruses coming
first on the evolutionary tree.
386
00:21:32,080 --> 00:21:35,560
Modern viruses can't replicate
without a host.
387
00:21:35,640 --> 00:21:38,880
It's likely that ancient viruses
couldn't either.
388
00:21:39,960 --> 00:21:44,280
But could early cells and viruses
have joined forces
389
00:21:44,360 --> 00:21:46,440
in a way that benefitted them both?
390
00:21:46,520 --> 00:21:51,320
Some new theories are suggesting
that viruses and cellular life
391
00:21:51,400 --> 00:21:54,960
co-evolved and actually
helped each other out,
392
00:21:55,040 --> 00:21:59,760
and potentially even helped out
the evolution of human life.
393
00:21:59,840 --> 00:22:03,160
How did this co-evolution work?
394
00:22:03,240 --> 00:22:05,160
We know that viruses today
395
00:22:05,240 --> 00:22:08,880
inject their genetic material
into cells to manipulate them.
396
00:22:09,920 --> 00:22:14,000
Perhaps early viruses manipulated
the genes of the first cells
397
00:22:14,080 --> 00:22:15,720
the same way.
398
00:22:15,800 --> 00:22:17,800
Think of this primordial soup,
399
00:22:17,880 --> 00:22:22,120
and the genes, the RNA,
that's in this primordial soup,
400
00:22:22,200 --> 00:22:25,360
being swapped between organisms,
kind of like a swap meet.
401
00:22:25,440 --> 00:22:27,360
You bring something
you don't need any more
402
00:22:27,440 --> 00:22:29,560
and you pass it along
to somebody else.
403
00:22:29,640 --> 00:22:33,120
So, in this way, organisms
sharing their genetic material
404
00:22:33,200 --> 00:22:34,440
back and forth,
405
00:22:34,520 --> 00:22:37,120
offers a competitive advantage
to each one.
406
00:22:37,200 --> 00:22:41,840
The virus might break off
bits of the host's genetic material
407
00:22:41,920 --> 00:22:43,320
and mix it with their own.
408
00:22:44,480 --> 00:22:46,480
When the virus attacks another cell,
409
00:22:46,560 --> 00:22:50,280
it could pass on the mixed genes
to its next host.
410
00:22:51,320 --> 00:22:56,480
In this sense, then,
viruses help stir things up.
411
00:22:56,560 --> 00:23:00,960
They shuttle genes between
widely different organisms
412
00:23:01,040 --> 00:23:05,280
and therefore help drive
evolution itself.
413
00:23:05,360 --> 00:23:08,360
Now, probably almost all of
these injections did nothing useful
414
00:23:08,440 --> 00:23:10,000
and maybe even killed the cell.
415
00:23:10,080 --> 00:23:13,400
But if one in a million injection
changed something for the better,
416
00:23:13,480 --> 00:23:16,640
made it more complex,
made it more able to survive,
417
00:23:16,720 --> 00:23:19,280
then that cell reproduced even more.
418
00:23:19,360 --> 00:23:24,000
If virally-enhanced cells thrived
in the primeval oceans,
419
00:23:24,080 --> 00:23:27,920
over time, they might have evolved
into more complex creatures,
420
00:23:28,000 --> 00:23:30,400
and eventually into us.
421
00:23:30,480 --> 00:23:32,360
What's so crazy
is to think about the fact
422
00:23:32,440 --> 00:23:35,000
that we actually could be descended
from viruses.
423
00:23:35,080 --> 00:23:37,720
I am sure that
a lot of my genetic code
424
00:23:37,800 --> 00:23:40,880
originally came from
the injection of a virus.
425
00:23:40,960 --> 00:23:44,600
I love the idea that
I might be descendent from a virus.
426
00:23:44,680 --> 00:23:47,160
Just coming from something
that simple
427
00:23:47,240 --> 00:23:50,040
and evolving into something
this complex
428
00:23:50,120 --> 00:23:52,280
is just a feat of nature.
429
00:23:52,360 --> 00:23:55,920
Viruses played a major part
in human evolution.
430
00:23:56,000 --> 00:24:00,720
Around 8% of human DNA
came from ancient viral infections.
431
00:24:00,800 --> 00:24:04,440
In fact, without them,
we wouldn't be human.
432
00:24:05,640 --> 00:24:09,720
In our brains, we actually have
relic viral DNA,
433
00:24:09,800 --> 00:24:12,360
so DNA that came from a virus.
434
00:24:12,440 --> 00:24:14,080
But this helps us.
435
00:24:14,160 --> 00:24:17,640
Without this, we don't think
we would have consciousness.
436
00:24:19,000 --> 00:24:21,200
We also think that viral DNA
437
00:24:21,280 --> 00:24:24,600
helped us develop an immune system
to fight off infection
438
00:24:24,680 --> 00:24:28,400
and gave us the ability
to digest starch.
439
00:24:30,080 --> 00:24:33,320
The microcosmos has guided
our evolution.
440
00:24:33,400 --> 00:24:35,960
It even created the air we breathe.
441
00:24:36,040 --> 00:24:40,840
But in doing so, it also triggered
the largest mass extinction
442
00:24:40,920 --> 00:24:43,080
the Earth has ever seen.
443
00:24:47,200 --> 00:24:50,760
Planet Earth, 2.5 billion years ago.
444
00:24:51,800 --> 00:24:55,280
The microcosmos
colonises Earth's oceans.
445
00:24:56,320 --> 00:24:59,640
This is not a world
we would recognise today.
446
00:25:00,800 --> 00:25:03,800
If you were to travel back in time,
just on Earth,
447
00:25:03,880 --> 00:25:06,680
to see what it was like
2.5 billion years ago,
448
00:25:06,760 --> 00:25:09,920
it would look really different
in many ways.
449
00:25:10,000 --> 00:25:13,480
There were oceans
and they had life in those oceans,
450
00:25:13,560 --> 00:25:17,720
but there weren't any land plants
or land animals.
451
00:25:17,800 --> 00:25:19,440
It was just bare rock.
452
00:25:19,520 --> 00:25:20,720
So, to think about it,
453
00:25:20,800 --> 00:25:23,440
a human going back in time to visit
the really early Earth,
454
00:25:23,520 --> 00:25:26,400
they would find
an utterly inhospitable planet.
455
00:25:26,480 --> 00:25:28,120
As a human, you'd be out of luck
456
00:25:28,200 --> 00:25:31,240
because there was no oxygen
in the atmosphere at that time,
457
00:25:31,320 --> 00:25:33,040
so hopefully you brought
a spacesuit.
458
00:25:34,160 --> 00:25:35,640
The atmosphere was fine
459
00:25:35,720 --> 00:25:39,280
for the billions of inhabitants
of the early microcosmos.
460
00:25:40,360 --> 00:25:42,000
They were very slow-paced
461
00:25:42,080 --> 00:25:45,520
and they did everything they did
without any oxygen in the air.
462
00:25:45,600 --> 00:25:49,320
But this tranquil existence
was about to change.
463
00:25:50,360 --> 00:25:53,400
For a long time, conditions on Earth
were fairly static.
464
00:25:53,480 --> 00:25:55,960
But then about two-and-a-half
billion years ago,
465
00:25:56,040 --> 00:25:59,400
an evolutionary glitch
changed everything.
466
00:26:00,480 --> 00:26:05,120
A clue to that glitch
rests in strange rocky mounds.
467
00:26:05,200 --> 00:26:06,960
Stromatolites.
468
00:26:08,080 --> 00:26:12,600
Stromatolites are almost like
microbial cities.
469
00:26:12,680 --> 00:26:16,080
If you zoom down on to their scale,
470
00:26:16,160 --> 00:26:20,320
you'll see layer
upon layer of bacteria,
471
00:26:20,400 --> 00:26:23,200
almost like
the high-rise skyscrapers
472
00:26:23,280 --> 00:26:25,400
of one of our cities.
473
00:26:25,480 --> 00:26:30,320
The microcosmic high-rises
are full of cyanobacteria.
474
00:26:30,400 --> 00:26:33,200
These bacteria can photosynthesise.
475
00:26:34,240 --> 00:26:36,720
Photosynthesis is a chemical reaction
476
00:26:36,800 --> 00:26:40,040
that takes place inside a plant,
producing food.
477
00:26:41,320 --> 00:26:44,520
Today, it's an important part of
our planet's existence.
478
00:26:45,760 --> 00:26:49,480
Two-and-a-half billion years ago,
it was revolutionary.
479
00:26:50,840 --> 00:26:53,640
And it happened
when ancient cyanobacteria
480
00:26:53,720 --> 00:26:56,720
similar to those
in the stromatolites mutated.
481
00:26:57,880 --> 00:27:02,600
This mutation allowed Cyanobacteria
to take the energy from sunlight
482
00:27:02,680 --> 00:27:06,400
and use it to make sugars
out of water and carbon dioxide.
483
00:27:06,480 --> 00:27:12,040
This gave cyanobacteria
a huge evolutionary edge.
484
00:27:12,120 --> 00:27:14,680
They could now make more energy
for themselves,
485
00:27:14,760 --> 00:27:17,400
so they could grow and reproduce
faster.
486
00:27:18,560 --> 00:27:21,720
For everything else,
it was a catastrophe.
487
00:27:21,800 --> 00:27:25,360
It produced oxygen
as a waste produce.
488
00:27:25,440 --> 00:27:29,000
Oxygen was no use to them,
so they released it into the air,
489
00:27:29,080 --> 00:27:33,000
transforming Earth's atmosphere
over millions of years.
490
00:27:33,080 --> 00:27:36,960
This by-product, oxygen,
is extremely toxic.
491
00:27:38,080 --> 00:27:41,880
The reason oxygen is so dangerous
is that it's very reactive.
492
00:27:41,960 --> 00:27:44,200
It loves to combine with everything.
493
00:27:44,280 --> 00:27:46,280
So, think about something rusting.
494
00:27:46,360 --> 00:27:48,160
Iron rusts because oxygen
495
00:27:48,240 --> 00:27:50,320
is actually combining with
the molecules.
496
00:27:50,400 --> 00:27:52,120
It's called oxidation.
497
00:27:52,200 --> 00:27:56,600
So when oxygen was first released,
it was tremendously dangerous.
498
00:27:56,680 --> 00:27:59,720
The new oxygen builds up
in the atmosphere,
499
00:27:59,800 --> 00:28:03,960
killing off species of microbes
everywhere on the planet.
500
00:28:04,040 --> 00:28:05,520
Right when this happened,
501
00:28:05,600 --> 00:28:08,480
you would have had
a mass extinction.
502
00:28:08,560 --> 00:28:12,120
This would've been
a global mass extinction event.
503
00:28:12,200 --> 00:28:15,680
This was an unprecedented
environmental disaster
504
00:28:15,760 --> 00:28:18,520
probably in the entire history of
the Earth up to that point,
505
00:28:18,600 --> 00:28:20,560
and I'm not even sure
it's been paralleled
506
00:28:20,640 --> 00:28:21,720
even up to today.
507
00:28:21,800 --> 00:28:24,120
This may have been
the single biggest catastrophe
508
00:28:24,200 --> 00:28:26,120
in our planet's history.
509
00:28:26,200 --> 00:28:28,360
This was the great oxidation event,
510
00:28:28,440 --> 00:28:31,840
and it changed our atmosphere,
it changed our planet,
511
00:28:31,920 --> 00:28:34,120
and it didn't just end there.
512
00:28:34,200 --> 00:28:35,840
Something changed again.
513
00:28:35,920 --> 00:28:39,640
Another mutation
allowed some of these bacteria
514
00:28:39,720 --> 00:28:43,360
to use that oxygen
in their own metabolism.
515
00:28:43,440 --> 00:28:46,520
And that was a huge change.
516
00:28:48,160 --> 00:28:51,720
The ability to use oxygen
was an incredible leap forward.
517
00:28:52,960 --> 00:28:56,840
The beauty of oxygen
is that it allows the metabolism
518
00:28:56,920 --> 00:29:00,240
to process nutrients
much more rapidly.
519
00:29:00,320 --> 00:29:03,960
It basically helps bodies
burn these materials,
520
00:29:04,040 --> 00:29:06,040
so that they can generate
a lot more energy
521
00:29:06,120 --> 00:29:07,520
a lot more quickly.
522
00:29:07,600 --> 00:29:11,320
Organisms that figured out
how to use oxygen for respiration
523
00:29:11,400 --> 00:29:13,800
ended up getting
a huge kickstart of energy
524
00:29:13,880 --> 00:29:17,000
and gave 'em a huge advantage
over other organisms.
525
00:29:17,080 --> 00:29:21,880
It supplied enough energy that
organisms could become more complex,
526
00:29:21,960 --> 00:29:24,360
larger, multi-cellular.
527
00:29:24,440 --> 00:29:30,040
Really the tapping into oxygen
and being able to use oxygen
528
00:29:30,120 --> 00:29:33,800
in our metabolism
meant that it was a game changer,
529
00:29:33,880 --> 00:29:37,360
that we could evolve in ways
that never would've been possible
530
00:29:37,440 --> 00:29:39,280
without cyanobacteria.
531
00:29:40,400 --> 00:29:43,400
Simple organisms
became more complex.
532
00:29:43,480 --> 00:29:46,880
Single-celled creatures
became multicellular.
533
00:29:47,920 --> 00:29:51,800
This gradual accumulation of oxygen
into the atmosphere of the Earth
534
00:29:51,880 --> 00:29:55,760
was huge for the multi-cellular
animal and life explosion
535
00:29:55,840 --> 00:29:57,840
that occurred as a result,
536
00:29:57,920 --> 00:29:59,840
and was one of
the most important events
537
00:29:59,920 --> 00:30:00,920
in Earth's history.
538
00:30:01,000 --> 00:30:03,880
This would've been
a complete transformation
539
00:30:03,960 --> 00:30:06,640
of the Earth's atmosphere
and physical setting.
540
00:30:06,720 --> 00:30:10,520
This is when the green Earth
started to evolve.
541
00:30:10,600 --> 00:30:14,400
The great oxidation event
changed the course of evolution,
542
00:30:14,480 --> 00:30:16,880
leading to our complex world.
543
00:30:18,720 --> 00:30:22,640
It is really hard to overemphasise
the importance of the microcosmos.
544
00:30:22,720 --> 00:30:26,160
Just the fact that I'm speaking
to you, I'm breathing in and out.
545
00:30:26,240 --> 00:30:27,320
I wouldn't be doing that
546
00:30:27,400 --> 00:30:29,600
without the tiniest organisms
on the planet.
547
00:30:30,880 --> 00:30:33,600
The microcosmos gave us life.
548
00:30:33,680 --> 00:30:36,440
Now it could wipe us out.
549
00:30:36,520 --> 00:30:40,160
Global warming is releasing
potentially lethal bacteria
550
00:30:40,240 --> 00:30:41,400
and viruses.
551
00:30:42,800 --> 00:30:46,960
Are we facing
a microcosmic zombie apocalypse?
552
00:30:51,720 --> 00:30:53,920
Siberia, present day.
553
00:30:54,000 --> 00:30:58,040
Rising temperatures are melting
the Arctic permafrost
554
00:30:58,120 --> 00:31:02,840
revealing land sealed under ice
for tens of thousands of years.
555
00:31:03,960 --> 00:31:07,280
As that permafrost
begins thawing out and melting
556
00:31:07,360 --> 00:31:08,680
with climate change,
557
00:31:08,760 --> 00:31:11,600
maybe that will release pathogens
558
00:31:11,680 --> 00:31:15,440
that have been locked up
for potentially thousands of years.
559
00:31:16,480 --> 00:31:21,200
In 2014, researchers investigated
melting Siberian tundra.
560
00:31:22,320 --> 00:31:24,640
A region larger than the USA.
561
00:31:25,720 --> 00:31:27,600
I've seen a lot of
science fiction movies
562
00:31:27,680 --> 00:31:29,760
where scientists are digging around
in the ice
563
00:31:29,840 --> 00:31:31,800
and find something bad
from a long time ago.
564
00:31:31,880 --> 00:31:35,200
Scientists took samples of
tundra soil to the lab
565
00:31:35,280 --> 00:31:37,000
and examined the contents.
566
00:31:37,080 --> 00:31:41,160
They found a frozen ancient virus.
567
00:31:41,240 --> 00:31:47,280
A virus locked in ice
from over 30,000 years ago.
568
00:31:48,320 --> 00:31:51,960
Isn't this the start of, like,
every horror movie?
569
00:31:52,040 --> 00:31:54,920
A scientist uncovers
some deep secret of nature
570
00:31:55,000 --> 00:31:59,360
and then just open it up
and unleash it on the world.
571
00:32:00,400 --> 00:32:03,400
Just like in a B movie,
the team fed the virus
572
00:32:03,480 --> 00:32:07,320
to living single-celled creatures
called amoebas
573
00:32:07,400 --> 00:32:09,880
to see if the virus still functioned
574
00:32:09,960 --> 00:32:12,360
after being frozen
for thousands of years.
575
00:32:13,400 --> 00:32:18,400
The virus woke up,
attacked the amoebas and replicated.
576
00:32:19,440 --> 00:32:21,960
Bringing this ancient virus
back to life
577
00:32:22,040 --> 00:32:25,000
was sort of waking up the undead.
578
00:32:26,320 --> 00:32:30,720
Scientists had no idea
how this zombie virus would behave.
579
00:32:33,640 --> 00:32:37,160
Something about it
was very, very different.
580
00:32:37,240 --> 00:32:40,680
It was huge
compared to normal viruses.
581
00:32:40,760 --> 00:32:43,840
It was substantially larger
582
00:32:43,920 --> 00:32:47,360
than any virus
that we had seen before.
583
00:32:47,440 --> 00:32:51,880
This is the Goliath of Goliaths
among viruses.
584
00:32:52,920 --> 00:32:56,080
So large, it looks
more like bacteria than a virus.
585
00:32:57,200 --> 00:33:01,280
We call these kinds of giant viruses
mimiviruses
586
00:33:01,360 --> 00:33:05,960
because they mimic other creatures
like bacteria.
587
00:33:07,000 --> 00:33:09,080
One way the virus mimics bacteria
588
00:33:09,160 --> 00:33:11,880
is in the amount of
its genetic material.
589
00:33:11,960 --> 00:33:14,280
It has 900 genes,
590
00:33:14,360 --> 00:33:17,680
eight times as many as
a regular virus.
591
00:33:17,760 --> 00:33:20,320
Viruses are very simple.
592
00:33:20,400 --> 00:33:23,040
They don't require a lot of genes
to function.
593
00:33:23,120 --> 00:33:28,920
But this virus has more genes
than necessary.
594
00:33:29,000 --> 00:33:32,600
What is it doing
with all these extra genes?
595
00:33:32,680 --> 00:33:36,480
We have now found other mimiviruses.
596
00:33:36,560 --> 00:33:38,960
20 years ago, we had no idea
597
00:33:39,040 --> 00:33:41,960
that this complex type of virus
even existed.
598
00:33:42,040 --> 00:33:45,280
We still don't know
what all the extra genes do.
599
00:33:46,720 --> 00:33:47,880
This type of virus
600
00:33:47,960 --> 00:33:51,120
might even be able to generate
its own energy,
601
00:33:51,200 --> 00:33:54,840
making it closer to bacteria
than other viruses.
602
00:33:56,080 --> 00:33:59,080
Because it has so many extra genes,
603
00:33:59,160 --> 00:34:02,840
this is a virus
that is not acting like a virus.
604
00:34:02,920 --> 00:34:06,720
We can't be sure
how the Siberian mimivirus
605
00:34:06,800 --> 00:34:08,960
will behave if released.
606
00:34:09,040 --> 00:34:12,200
And even if it only attacks amoebas,
607
00:34:12,280 --> 00:34:14,960
there could be
other large complex viruses
608
00:34:15,040 --> 00:34:16,280
buried in the ice.
609
00:34:17,680 --> 00:34:20,160
They may not be so safe.
610
00:34:20,240 --> 00:34:23,560
We know that there are
large regions of the Earth
611
00:34:23,640 --> 00:34:25,640
that are locked in ice right now.
612
00:34:25,720 --> 00:34:30,800
There could be viruses
that live inside that ice
613
00:34:30,880 --> 00:34:35,200
that, if the Earth gets too warm,
could reactivate.
614
00:34:35,280 --> 00:34:39,360
These viruses could potentially be
a threat to us.
615
00:34:40,480 --> 00:34:45,120
Recently, other dangerous
frozen zombies have reanimated,
616
00:34:45,200 --> 00:34:47,840
hidden in the dead.
617
00:34:47,920 --> 00:34:49,920
We tend to think of people
who died in the past
618
00:34:50,000 --> 00:34:52,400
as not being able to affect us
at all, right?
619
00:34:52,480 --> 00:34:54,640
They're gone, their germs are gone.
620
00:34:54,720 --> 00:34:56,880
Unfortunately,
this isn't exactly true.
621
00:34:56,960 --> 00:35:01,040
So, for people who are buried
in tundra that's been frozen,
622
00:35:01,120 --> 00:35:02,680
they never really disappeared.
623
00:35:02,760 --> 00:35:05,560
And now, unfortunately,
as the climate warms,
624
00:35:05,640 --> 00:35:07,360
these tundra environments
625
00:35:07,440 --> 00:35:12,320
are releasing frozen people
and animals
626
00:35:12,400 --> 00:35:14,720
who died thousands of years ago.
627
00:35:16,000 --> 00:35:18,960
But it's not the dead people
and animals that threaten us.
628
00:35:19,040 --> 00:35:21,360
It's the microbes inside them.
629
00:35:22,640 --> 00:35:26,040
In 2016, that threat became real,
630
00:35:26,120 --> 00:35:29,160
when another area of Siberia thawed.
631
00:35:29,240 --> 00:35:31,880
A 12-year-old boy died
632
00:35:31,960 --> 00:35:35,320
and dozens of people
needed medical treatment.
633
00:35:35,400 --> 00:35:38,040
2,000 reindeer also perished.
634
00:35:38,120 --> 00:35:43,440
The culprit? Reanimated bacteria
called anthrax
635
00:35:43,520 --> 00:35:45,880
inside a melting reindeer.
636
00:35:45,960 --> 00:35:50,560
Anthrax is a common microbe
found in soil.
637
00:35:50,640 --> 00:35:55,040
In medieval times,
sometimes farmers would come back
638
00:35:55,120 --> 00:35:58,520
to find entire fields of
dead animals.
639
00:35:58,600 --> 00:36:01,000
They didn't understand at the time
what was going on.
640
00:36:01,080 --> 00:36:03,960
They attribute it to cursed fields.
641
00:36:04,040 --> 00:36:08,160
But we now know that these were
outbreaks of anthrax.
642
00:36:09,200 --> 00:36:12,760
The defrosted reindeer died
nearly a century ago.
643
00:36:12,840 --> 00:36:17,400
The anthrax that killed it
was safely locked away in the ice.
644
00:36:18,560 --> 00:36:23,720
The thawing out of regions
like the Siberian permafrost
645
00:36:23,800 --> 00:36:27,280
could be almost like
the inadvertent opening
646
00:36:27,360 --> 00:36:29,160
of Pandora's box.
647
00:36:29,240 --> 00:36:32,000
One you open it, you don't know
what's gonna come out.
648
00:36:32,080 --> 00:36:36,720
It could be releasing
ancient preserved microbes,
649
00:36:36,800 --> 00:36:41,760
bacteria or viruses
that have been laying dormant
650
00:36:41,840 --> 00:36:44,880
for hundreds,
if not thousands, of years.
651
00:36:44,960 --> 00:36:48,280
If these microbes are actually
very different
652
00:36:48,360 --> 00:36:50,160
from what we have on Earth today,
653
00:36:50,240 --> 00:36:52,560
if we encountered these microbes,
654
00:36:52,640 --> 00:36:54,720
it's not really clear
what would happen
655
00:36:54,800 --> 00:36:56,040
with our immune systems.
656
00:36:56,120 --> 00:36:58,600
You know, it could be totally fine.
657
00:36:58,680 --> 00:37:02,040
But it could also wreak
complete havoc on us.
658
00:37:02,120 --> 00:37:05,280
It's also not clear if modern drugs
659
00:37:05,360 --> 00:37:09,680
would help us beat
any ancient microbes we unleash.
660
00:37:10,720 --> 00:37:15,200
Now, as humanity expands
beyond Earth to new worlds,
661
00:37:15,280 --> 00:37:19,360
will we carry our microcosmos
with us into space,
662
00:37:19,440 --> 00:37:23,560
or have we already infected
our cosmic neighbourhood?
663
00:37:27,880 --> 00:37:32,520
Space is no longer
the final frontier of the future.
664
00:37:32,600 --> 00:37:35,000
We're already exploring
the solar system.
665
00:37:36,160 --> 00:37:39,960
We've sent probes to the planets
and put boots on the moon.
666
00:37:41,240 --> 00:37:46,880
Now NASA plans to land astronauts
on Mars by the 2030s.
667
00:37:47,920 --> 00:37:50,160
As a science fiction nerd myself,
668
00:37:50,240 --> 00:37:51,960
without even breaking a sweat,
669
00:37:52,040 --> 00:37:55,280
I could name ten movies
where people go to another planet
670
00:37:55,360 --> 00:37:57,520
and some disease,
some alien lifeform,
671
00:37:57,600 --> 00:38:00,320
is unleashed on humans
and kills us all.
672
00:38:00,400 --> 00:38:02,400
I think that has it
exactly backwards.
673
00:38:02,480 --> 00:38:05,200
If we try to settle on
other planets,
674
00:38:05,280 --> 00:38:07,240
we have to be really, really careful
675
00:38:07,320 --> 00:38:10,800
and really, really think about
how we are affecting them.
676
00:38:10,880 --> 00:38:14,440
As we launch more and more missions
into space,
677
00:38:14,520 --> 00:38:18,000
we risk sending Earth's microcosmos
with them,
678
00:38:18,080 --> 00:38:20,720
endangering the health of
the solar system.
679
00:38:21,760 --> 00:38:25,480
And if we find a planet
that actually has its own biosphere,
680
00:38:25,560 --> 00:38:28,560
that has life of its own,
we need to be very careful about
681
00:38:28,640 --> 00:38:31,360
how we introduce our microbes
to their microbes,
682
00:38:31,440 --> 00:38:33,720
because it could really be
catastrophic for them.
683
00:38:33,800 --> 00:38:37,240
It's serious because
we're looking at places like Mars,
684
00:38:37,320 --> 00:38:40,680
like Titan, Saturn's moon,
like comets,
685
00:38:40,760 --> 00:38:43,920
where life, or at least
pre-biotic life, could've existed,
686
00:38:44,000 --> 00:38:48,640
or in the past, there could've been
a much more habitable environment.
687
00:38:48,720 --> 00:38:52,320
So it's entirely possible
that we are polluting,
688
00:38:52,400 --> 00:38:57,640
we are infecting these other objects
with our own bacteria.
689
00:38:57,720 --> 00:39:00,720
If we contaminate a pristine world,
690
00:39:00,800 --> 00:39:03,600
we won't know which microbes
were there first.
691
00:39:04,720 --> 00:39:07,800
Our bugs could even kill off
the native ones.
692
00:39:08,920 --> 00:39:10,720
It may have already happened.
693
00:39:15,160 --> 00:39:20,800
Is it possible that we've already
sent pathogens out among the stars,
694
00:39:20,880 --> 00:39:22,960
hitching rides on our spacecraft?
695
00:39:24,000 --> 00:39:26,000
We've sent missions to other worlds,
696
00:39:26,080 --> 00:39:29,080
and it could be that
during those exploration periods,
697
00:39:29,160 --> 00:39:32,160
when we didn't really understand
the microcosmos,
698
00:39:32,240 --> 00:39:33,720
we have already sent bacteria,
699
00:39:33,800 --> 00:39:36,040
we've already sent viruses
to those worlds,
700
00:39:36,120 --> 00:39:38,320
so we could've already
infected them.
701
00:39:38,400 --> 00:39:40,120
We are absolutely sure
702
00:39:40,200 --> 00:39:43,600
that we have already delivered
some aspects of our own microcosmos
703
00:39:43,680 --> 00:39:45,560
to different worlds out there.
704
00:39:45,640 --> 00:39:47,080
Every spacecraft we send,
705
00:39:47,160 --> 00:39:50,440
we cannot get rid of
every tiny little bacterium,
706
00:39:50,520 --> 00:39:51,920
every tiny little virus.
707
00:39:52,000 --> 00:39:55,080
Bits of us already are on Mars.
708
00:39:57,480 --> 00:39:59,360
You're looking good.
709
00:39:59,440 --> 00:40:00,680
The Apollo 12 mission
710
00:40:00,760 --> 00:40:05,080
brought back bits of
the lunar robotic probe, Surveyor 3,
711
00:40:05,160 --> 00:40:06,640
it found on the moon.
712
00:40:06,720 --> 00:40:11,160
Analysis of the probe
found a bacterial contamination.
713
00:40:11,240 --> 00:40:13,400
We don't know where it came from.
714
00:40:13,480 --> 00:40:16,760
If that thing was infected
before we sent it to the moon
715
00:40:16,840 --> 00:40:19,840
and it sat on the moon's surface
for two years in a vacuum,
716
00:40:19,920 --> 00:40:22,560
changing temperatures,
radiation from space,
717
00:40:22,640 --> 00:40:26,280
that really is telling us
that we can infect other planets,
718
00:40:26,360 --> 00:40:29,320
and we should take this
very seriously.
719
00:40:29,400 --> 00:40:32,320
We're ramping up our space missions.
720
00:40:32,400 --> 00:40:34,280
We're sending probe after probe
721
00:40:34,360 --> 00:40:37,560
to planets all throughout
the solar system.
722
00:40:37,640 --> 00:40:42,040
Taking care to not send
our own diseases
723
00:40:42,120 --> 00:40:45,440
out onto other planets is something
we actually have to care about.
724
00:40:46,480 --> 00:40:47,560
NASA does care.
725
00:40:47,640 --> 00:40:49,440
Before launching a new probe,
726
00:40:49,520 --> 00:40:53,680
a planetary protection team
deep cleans every inch.
727
00:40:54,720 --> 00:40:57,440
You try to bake the space craft,
you try to disinfect things.
728
00:40:57,520 --> 00:41:00,160
You build everything
and keep everything
729
00:41:00,240 --> 00:41:01,240
within a clean room,
730
00:41:01,320 --> 00:41:05,880
which has a pressure
that blows dust out.
731
00:41:05,960 --> 00:41:08,040
Everybody wears what are called
bunny suits,
732
00:41:08,120 --> 00:41:10,240
so nobody touches anything directly.
733
00:41:10,320 --> 00:41:11,960
But then, that's still not enough,
734
00:41:12,040 --> 00:41:14,000
because microbes
are incredibly hardy.
735
00:41:15,240 --> 00:41:18,640
It's even more difficult to kill
microcosmic stowaways
736
00:41:18,720 --> 00:41:20,960
if they're travelling
inside an astronaut.
737
00:41:22,000 --> 00:41:24,400
In the not-too-distant future,
738
00:41:24,480 --> 00:41:26,960
we'll start sending
not robot explorers,
739
00:41:27,040 --> 00:41:30,240
not probes to Mars, but people.
740
00:41:30,320 --> 00:41:35,680
An inherently dirty, mucky organism
like myself.
741
00:41:35,760 --> 00:41:39,920
You can't sterilise a human.
You can't remove all bacteria.
742
00:41:40,000 --> 00:41:41,240
We have to realise that
743
00:41:41,320 --> 00:41:43,480
we are bringing the microcosmos
with us.
744
00:41:43,560 --> 00:41:47,240
And we may change worlds entirely
without even noticing it.
745
00:41:49,160 --> 00:41:53,400
Planetary protection continues
once the mission has landed.
746
00:41:53,480 --> 00:41:55,800
So, thinking about
planetary protection
747
00:41:55,880 --> 00:41:59,200
means we really have to think about
our actions in a whole new way.
748
00:41:59,280 --> 00:42:02,760
For example, if the rover
were to find a pool of water,
749
00:42:02,840 --> 00:42:04,480
we really couldn't get that close,
750
00:42:04,560 --> 00:42:07,520
because we could not guarantee
that even after all of this time,
751
00:42:07,600 --> 00:42:09,320
there wasn't some kind of microbe
752
00:42:09,400 --> 00:42:11,720
that could jump ship
into that pool of water
753
00:42:11,800 --> 00:42:15,360
and then live happily on Mars
and reproduce.
754
00:42:18,000 --> 00:42:21,160
Potentially our impact
could be absolutely devastating
755
00:42:21,240 --> 00:42:23,880
on worlds that either have life
or emerging life.
756
00:42:23,960 --> 00:42:27,120
And so we just need to take
that responsibility seriously
757
00:42:27,200 --> 00:42:30,040
and be careful with the way
in which we explore them.
758
00:42:31,080 --> 00:42:34,320
Humans bear a responsibility
for the safety of the cosmos.
759
00:42:34,400 --> 00:42:37,200
Our track record on Earth
isn't good.
760
00:42:38,760 --> 00:42:42,000
When we look at the pattern of
exploration or colonisation
761
00:42:42,080 --> 00:42:45,440
that we use as humans,
we are really invasive.
762
00:42:45,520 --> 00:42:47,520
We see a lot of destruction
in our path.
763
00:42:47,600 --> 00:42:50,480
And we have to wonder
if that's what we're going to do
764
00:42:50,560 --> 00:42:54,720
when we start to really explore
and colonise outside of Earth.
765
00:42:54,800 --> 00:42:57,200
Like viruses,
we also insist on spreading.
766
00:42:57,280 --> 00:42:59,360
We insist on spreading around
our world,
767
00:42:59,440 --> 00:43:00,880
around our solar system.
768
00:43:00,960 --> 00:43:04,800
There is a great chance
that we will cause utter destruction
769
00:43:04,880 --> 00:43:05,960
wherever we go.
770
00:43:07,000 --> 00:43:11,160
Our relationship
with the microcosmos is complicated.
771
00:43:11,240 --> 00:43:16,480
It's killed millions of people,
but without it, we wouldn't be here.
772
00:43:17,640 --> 00:43:19,040
This time we're living in
773
00:43:19,120 --> 00:43:21,600
is really causing us to reflect on
the microcosmos.
774
00:43:21,680 --> 00:43:24,040
And the better we understand
these micro organisms,
775
00:43:24,120 --> 00:43:27,440
the better able we are to deal with
what's happening today.
776
00:43:27,520 --> 00:43:29,840
The coronavirus crisis reminds us
777
00:43:29,920 --> 00:43:32,640
we need to respect the world
we cannot see,
778
00:43:32,720 --> 00:43:37,440
and recognise that the microcosmos
is every bit as important to us
779
00:43:37,520 --> 00:43:38,920
as the greater universe.
780
00:43:40,040 --> 00:43:42,440
It's so easy,
especially right now in history,
781
00:43:42,520 --> 00:43:43,600
to hear the word "virus"
782
00:43:43,680 --> 00:43:46,400
and think about how harmful
they are, how dangerous they are.
783
00:43:46,480 --> 00:43:48,560
But remember that you are actually
a creature
784
00:43:48,640 --> 00:43:49,880
built of viruses yourself.
785
00:43:49,960 --> 00:43:51,360
As far as we know,
786
00:43:51,440 --> 00:43:53,520
we've never been
without the microcosmos.
787
00:43:53,600 --> 00:43:57,200
Microbes were here before us,
they'll probably be here after us,
788
00:43:57,280 --> 00:43:58,800
and we need them to live.
789
00:44:00,640 --> 00:44:03,720
The microcosmos,
it's absolutely essential.
790
00:44:03,800 --> 00:44:05,960
We couldn't function,
we wouldn't survive,
791
00:44:06,040 --> 00:44:08,200
we wouldn't be here without it.
792
00:44:08,280 --> 00:44:13,520
But it's also our greatest ally
and it's also our greatest enemy.
793
00:44:13,600 --> 00:44:15,600
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