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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:01,780 --> 00:00:04,015 Death will someday come for us all. 2 00:00:06,085 --> 00:00:10,421 But are the dead really gone forever? 3 00:00:10,423 --> 00:00:14,558 Advances in medicine and bold leaps in computer science 4 00:00:14,560 --> 00:00:18,562 may soon allow the dead to walk the earth again... 5 00:00:18,564 --> 00:00:22,633 or survive in some other strange, new form. 6 00:00:22,635 --> 00:00:25,870 Can we resurrect the dead? 7 00:00:31,243 --> 00:00:36,247 Space, time, life itself. 8 00:00:38,150 --> 00:00:43,120 The secrets of the cosmos lie through the wormhole. 9 00:00:43,122 --> 00:00:47,122 Through the Wormhole 03x06 Can We Resurrect the Dead? Original Air Date on July 11, 2012 10 00:00:47,147 --> 00:00:51,147 == sync, corrected by elderman == 11 00:00:56,076 --> 00:01:00,246 Death is our ultimate destination, 12 00:01:00,248 --> 00:01:04,250 a place from which no one ever returns. 13 00:01:04,252 --> 00:01:07,453 But what if death was not the end? 14 00:01:07,455 --> 00:01:09,955 We each have a genetic blueprint, 15 00:01:09,957 --> 00:01:12,258 one that science can now read. 16 00:01:12,260 --> 00:01:17,530 Soon, it may be possible to reproduce my body after I die. 17 00:01:17,532 --> 00:01:20,733 But what about the lifetime of knowledge and experience 18 00:01:20,735 --> 00:01:22,835 contained in here? 19 00:01:22,837 --> 00:01:24,737 Will we ever have the tools 20 00:01:24,739 --> 00:01:28,507 to raise body and soul from the dead? 21 00:01:33,146 --> 00:01:38,250 All of us must eventually come face-to-face with death. 22 00:01:38,252 --> 00:01:42,121 No matter how hard we wish to hold on to someone we love, 23 00:01:42,123 --> 00:01:47,226 sometimes, we just have to let go. 24 00:01:47,228 --> 00:01:50,996 I had a dog I loved to go exploring with. 25 00:01:54,602 --> 00:01:57,703 But worms had eaten away at his heart. 26 00:02:06,980 --> 00:02:11,650 The pain of saying goodbye forever cuts deep, 27 00:02:11,652 --> 00:02:13,986 but it is unavoidable. 28 00:02:18,258 --> 00:02:20,626 Or is it? 29 00:02:32,505 --> 00:02:35,441 This patient is dead. 30 00:02:35,443 --> 00:02:38,577 He has no heartbeat, no respiration, 31 00:02:38,579 --> 00:02:42,081 no blood flowing through his heart. 32 00:02:42,083 --> 00:02:47,786 But today, he will be brought back to life by this man, 33 00:02:47,788 --> 00:02:53,425 heart surgeon John Elefteriades of Yale-New Haven hospital. 34 00:02:53,427 --> 00:02:59,265 John regularly kills his patients, then resurrects them. 35 00:02:59,267 --> 00:03:04,403 Once I got to medical school and residency, 36 00:03:04,405 --> 00:03:06,939 heart surgery was the only thing I ever wanted to do. 37 00:03:06,941 --> 00:03:11,110 At that time, it was kind of like being a fighter pilot 38 00:03:11,112 --> 00:03:13,078 within medicine, if you know what I mean. 39 00:03:13,080 --> 00:03:16,315 It was exploring the frontiers. It was high-risk. 40 00:03:16,317 --> 00:03:21,553 John still flies at the edge of the surgical horizon. 41 00:03:23,056 --> 00:03:27,226 Today, he's trying to repair a severely damaged heart, 42 00:03:27,228 --> 00:03:32,231 a heart that can't be fixed while blood flows through it. 43 00:03:34,901 --> 00:03:38,671 The heart must be shut down, but doing so 44 00:03:38,673 --> 00:03:41,473 will cut off the blood supply to the patient's brain, 45 00:03:41,475 --> 00:03:43,842 starving it of oxygen. 46 00:03:46,513 --> 00:03:50,849 John needs 45 minutes to operate. 47 00:03:50,851 --> 00:03:52,384 At normal temperatures, 48 00:03:52,386 --> 00:03:55,454 the brain will begin to die after just five minutes. 49 00:03:57,957 --> 00:04:00,259 John's radical solution 50 00:04:00,261 --> 00:04:04,596 is to freeze the patient into a state of suspended animation. 51 00:04:06,901 --> 00:04:09,001 The brain doesn't tolerate 52 00:04:09,003 --> 00:04:12,738 more than a momentary interruption of blood flow. 53 00:04:12,740 --> 00:04:14,707 If the interruption of blood flow 54 00:04:14,709 --> 00:04:16,275 goes beyond several minutes, 55 00:04:16,277 --> 00:04:18,277 then the brain cells start to die, 56 00:04:18,279 --> 00:04:22,081 and that's where the protection of low temperature 57 00:04:22,083 --> 00:04:24,750 gives us the opportunity to protect 58 00:04:24,752 --> 00:04:26,618 the very vulnerable brain. 59 00:04:26,620 --> 00:04:30,989 The patient's warm blood has been drained from his body, 60 00:04:30,991 --> 00:04:34,259 run through a bypass machine filled with ice, 61 00:04:34,261 --> 00:04:38,497 then pumped back through his veins and arteries. 62 00:04:38,499 --> 00:04:42,935 This has gradually cooled him down to 18 degrees Centigrade -- 63 00:04:42,937 --> 00:04:46,605 55 Fahrenheit. 64 00:04:46,607 --> 00:04:52,010 The activity of his cells and neurons cannot be measured. 65 00:04:54,214 --> 00:04:57,282 If you had a general practitioner 66 00:04:57,284 --> 00:05:00,352 or a cardiologist or somebody come in 67 00:05:00,354 --> 00:05:04,189 and use their regular criteria for life or death, 68 00:05:04,191 --> 00:05:06,592 all the criteria for death would be fulfilled. 69 00:05:06,594 --> 00:05:10,829 At this point, the heart-lung machine and the respirator -- 70 00:05:10,831 --> 00:05:14,867 the devices that keep him alive -- are shut off -- 71 00:05:14,869 --> 00:05:18,203 no breathing, no blood pumping -- 72 00:05:18,205 --> 00:05:22,841 a condition virtually identical to death. 73 00:05:25,879 --> 00:05:29,882 John has 45 minutes to operate in safety. 74 00:05:29,884 --> 00:05:33,385 After an hour, brain damage will set in. 75 00:05:33,387 --> 00:05:37,122 Now his decades of experience come into play. 76 00:05:37,124 --> 00:05:40,426 We're still in suspended animation. 77 00:05:43,430 --> 00:05:46,598 So we've got 15 minutes to go for safety. 78 00:05:48,435 --> 00:05:50,102 Finally, 79 00:05:50,104 --> 00:05:52,871 John and his team manage to complete the repairs 80 00:05:52,873 --> 00:05:55,441 with seven minutes to spare. 81 00:05:55,443 --> 00:05:59,878 The patient has been virtually dead for 38 minutes. 82 00:05:59,880 --> 00:06:02,881 They slowly bring back life support, 83 00:06:02,883 --> 00:06:04,983 returning him to the land of the living with 84 00:06:04,985 --> 00:06:07,619 no damage to the brain. 85 00:06:11,191 --> 00:06:15,294 Each and every day, I'm amazed that this can be done. 86 00:06:15,296 --> 00:06:18,831 The definition of death has changed, really, 87 00:06:18,833 --> 00:06:21,266 and death is death when it's permanent. 88 00:06:21,268 --> 00:06:22,568 But those criteria 89 00:06:22,570 --> 00:06:26,939 in this very, very special high-technology scenario 90 00:06:26,941 --> 00:06:30,108 of suspended animation or deep hypothermic arrest -- 91 00:06:30,110 --> 00:06:32,945 those criteria for death don't really apply. 92 00:06:32,947 --> 00:06:35,914 But can we bring life back 93 00:06:35,916 --> 00:06:39,551 to those who die in less controlled situations? 94 00:06:45,692 --> 00:06:48,894 Lance Becker is the director of the University of Pennsylvania's 95 00:06:48,896 --> 00:06:51,930 Center for Resuscitation Science. 96 00:06:51,932 --> 00:06:55,067 He believes the key to resurrection 97 00:06:55,069 --> 00:06:57,736 is buried deep within our cells. 98 00:06:57,738 --> 00:07:01,740 Well, what we've known for just literally thousands of years 99 00:07:01,742 --> 00:07:07,012 is that, if you keep meat cold, it keeps longer. 100 00:07:07,014 --> 00:07:11,183 The decay process, which is actually that death process -- 101 00:07:11,185 --> 00:07:16,054 All of those things are slowed down 102 00:07:16,056 --> 00:07:18,123 in the cold setting. 103 00:07:18,125 --> 00:07:19,791 When the temperature comes down, 104 00:07:19,793 --> 00:07:21,827 the cells don't need as much oxygen, 105 00:07:21,829 --> 00:07:25,297 they don't metabolize as much, 106 00:07:25,299 --> 00:07:31,403 and they essentially sort of go into slow-mo, hibernation-style. 107 00:07:33,106 --> 00:07:38,644 Your body is made of tens of trillions of living cells. 108 00:07:38,646 --> 00:07:42,848 Regulatory genes tell these cells how to behave. 109 00:07:42,850 --> 00:07:46,852 Think of them as the cells' operating system. 110 00:07:46,854 --> 00:07:50,222 At the end of a cell's life, the genes produce 111 00:07:50,224 --> 00:07:53,692 destructive enzymes that tear the cell apart. 112 00:07:53,694 --> 00:07:59,531 Every day, roughly 50 billion of your cells die. 113 00:08:01,601 --> 00:08:04,102 When something goes very wrong -- 114 00:08:04,104 --> 00:08:07,606 say, you suffer a cardiac arrest -- 115 00:08:07,608 --> 00:08:11,109 the injured cells sound an alarm, 116 00:08:11,111 --> 00:08:16,048 telling their healthy neighbors it's time to die. 117 00:08:16,050 --> 00:08:18,984 This sets off a wave of cellular suicide 118 00:08:18,986 --> 00:08:21,820 that spreads rapidly across the body. 119 00:08:22,889 --> 00:08:26,425 We don't die by accident. 120 00:08:26,427 --> 00:08:31,863 There's biological programming 121 00:08:31,865 --> 00:08:36,168 that actually controls the way we die. 122 00:08:36,170 --> 00:08:38,570 And in that programming 123 00:08:38,572 --> 00:08:42,874 is the opportunity for modifying that program 124 00:08:42,876 --> 00:08:45,844 so that we can alter the outcome -- 125 00:08:45,846 --> 00:08:47,546 bring someone back to life. 126 00:08:47,548 --> 00:08:51,416 To find out what triggers the death program, 127 00:08:51,418 --> 00:08:55,921 Lance took healthy cells and starved them of oxygen. 128 00:08:55,923 --> 00:08:59,858 He expected most of the cells to die 129 00:08:59,860 --> 00:09:05,097 and the survivors to flourish when oxygen was restored. 130 00:09:05,099 --> 00:09:06,498 So, what I found 131 00:09:06,500 --> 00:09:10,135 was the opposite of what we thought we would find, 132 00:09:10,137 --> 00:09:12,404 which is the cells without oxygen 133 00:09:12,406 --> 00:09:15,007 just sort of laid there. 134 00:09:15,009 --> 00:09:18,644 They didn't do anything, but they didn't die. 135 00:09:18,646 --> 00:09:22,781 But what happened was, when we reoxygenated those cells, 136 00:09:22,783 --> 00:09:25,651 that's when cell death occurred. 137 00:09:25,653 --> 00:09:27,886 So it is a little bit ironic 138 00:09:27,888 --> 00:09:32,991 that oxygen, the molecule that we love and that we live with, 139 00:09:32,993 --> 00:09:37,229 becomes the molecule that drives death. 140 00:09:37,231 --> 00:09:42,100 Somehow, reintroducing oxygen into cells 141 00:09:42,102 --> 00:09:44,436 triggers the death signal 142 00:09:44,438 --> 00:09:47,539 that causes them to commit mass suicide. 143 00:09:48,742 --> 00:09:52,411 Freezing seems to interrupt this process. 144 00:09:52,413 --> 00:09:54,246 Lance pressed on, 145 00:09:54,248 --> 00:09:57,549 knowing that, if he found the death signal's source, 146 00:09:57,551 --> 00:10:00,452 he might be able to stop it from transmitting 147 00:10:00,454 --> 00:10:03,321 without the need for freezing. 148 00:10:03,323 --> 00:10:05,357 As we began to ask ourselves, 149 00:10:05,359 --> 00:10:08,927 "What could explain this sort of bizarre behavior?" 150 00:10:08,929 --> 00:10:12,230 We started seeing cellular pathways. 151 00:10:12,232 --> 00:10:17,169 All of the paths led us to the organelle inside our cells 152 00:10:17,171 --> 00:10:19,771 that we call the mitochondria. 153 00:10:21,441 --> 00:10:26,978 Mitochondria lie deep within every single cell of your body. 154 00:10:26,980 --> 00:10:30,515 They take the food you eat and the oxygen you breathe 155 00:10:30,517 --> 00:10:33,985 and convert them into chemical energy. 156 00:10:33,987 --> 00:10:39,624 In some ways, it's a little bit like a nuclear power plant. 157 00:10:39,626 --> 00:10:42,060 And you know how, in a nuclear power plant, 158 00:10:42,062 --> 00:10:45,497 there are rods that come together and they produce the heat, 159 00:10:45,499 --> 00:10:47,232 and if you don't control that process, 160 00:10:47,234 --> 00:10:49,901 you end up with Chernobyl. 161 00:10:49,903 --> 00:10:54,740 What happens is, after one mitochondria goes nuclear, 162 00:10:54,742 --> 00:10:57,909 it starts to trigger a chain reaction 163 00:10:57,911 --> 00:11:00,412 that amplifies the death signal, 164 00:11:00,414 --> 00:11:04,649 and that death signal can be spread throughout the body. 165 00:11:05,719 --> 00:11:08,854 Lance and his team suspect 166 00:11:08,856 --> 00:11:12,657 we might be able to stop this chain reaction 167 00:11:12,659 --> 00:11:15,093 by poisoning our mitochondria 168 00:11:15,095 --> 00:11:19,431 with sulfide, cyanide, and carbon monoxide. 169 00:11:19,433 --> 00:11:22,467 A finely calibrated dose of these toxins 170 00:11:22,469 --> 00:11:24,236 might disarm the death signal. 171 00:11:24,238 --> 00:11:26,371 It will be quicker than freezing, 172 00:11:26,373 --> 00:11:30,342 and it could reverse a cellular meltdown. 173 00:11:33,012 --> 00:11:35,413 So, ideally, what we'd like to do 174 00:11:35,415 --> 00:11:39,084 is we'd like to get a few of those molecules on board 175 00:11:39,086 --> 00:11:42,354 as we're beginning to bring oxygen back to the patient. 176 00:11:42,356 --> 00:11:45,557 We think we can restart that mitochondria, 177 00:11:45,559 --> 00:11:49,628 have it convert back to producing energy 178 00:11:49,630 --> 00:11:53,465 instead of producing death. 179 00:11:53,467 --> 00:11:56,735 These treatments are still highly experimental. 180 00:11:56,737 --> 00:12:00,205 But if doctors can silence the death signal, 181 00:12:00,207 --> 00:12:02,374 it may soon be commonplace 182 00:12:02,376 --> 00:12:05,911 to revive the dying and the recently dead. 183 00:12:06,947 --> 00:12:09,181 Medical science has already proven 184 00:12:09,183 --> 00:12:10,916 that the dead can live again 185 00:12:10,918 --> 00:12:14,820 under a very controlled set of circumstances. 186 00:12:14,822 --> 00:12:17,088 But can it take us further? 187 00:12:18,291 --> 00:12:21,393 What if we could grow the dead back to life? 188 00:12:23,424 --> 00:12:26,092 Imagine how much richer humanity might be 189 00:12:27,085 --> 00:12:31,121 if we could raise Einstein or Mozart from the grave 190 00:12:31,123 --> 00:12:34,524 or how much it would mean to us personally 191 00:12:34,526 --> 00:12:38,795 if we could bring back the loved ones we have lost? 192 00:12:41,065 --> 00:12:43,633 It may be possible. 193 00:12:43,635 --> 00:12:48,338 Cloning has opened up a new road to resurrection... 194 00:12:48,340 --> 00:12:50,740 But should we take it? 195 00:12:52,209 --> 00:12:56,947 Bob Lanza was born into a working-class Boston family. 196 00:12:56,949 --> 00:12:59,916 Today, he owns an island in Massachusetts 197 00:12:59,918 --> 00:13:02,385 and lives in a sprawling compound 198 00:13:02,387 --> 00:13:06,356 that's part house, part natural-history museum. 199 00:13:06,358 --> 00:13:11,428 These are the fruits of a career in biotechnology. 200 00:13:11,430 --> 00:13:13,863 Here's a brontosaurus femur. 201 00:13:13,865 --> 00:13:16,099 One of the first things people ask me when they come into the house 202 00:13:16,101 --> 00:13:17,867 is, "Bob, are you gonna clone that?" 203 00:13:17,869 --> 00:13:19,970 And I tell them, "you can't clone from stone. 204 00:13:19,972 --> 00:13:21,104 You need a living cell." 205 00:13:21,106 --> 00:13:24,741 Over the last decade, 206 00:13:24,743 --> 00:13:29,879 Bob has successfully cloned mice, cows, cats, dogs, 207 00:13:29,881 --> 00:13:33,550 pigs, sheep, and horses. 208 00:13:33,552 --> 00:13:37,887 In 2001, he used frozen cells to successfully resurrect 209 00:13:37,889 --> 00:13:42,959 an extinct southeast Asian ox called a Gaur, 210 00:13:42,961 --> 00:13:47,197 using an American cow as a surrogate mother. 211 00:13:47,199 --> 00:13:48,732 Everyone said, "no, that won't work. 212 00:13:48,734 --> 00:13:51,067 You can't clone one species using the egg from another one." 213 00:13:51,069 --> 00:13:53,236 And I said, "no, no, no. If we do it and it's close enough, 214 00:13:53,238 --> 00:13:54,437 we should get it to work." 215 00:13:54,439 --> 00:13:56,539 So I actually took skin cells from the Gaur, 216 00:13:56,541 --> 00:13:59,442 and I actually put the DNA into an ordinary cow egg. 217 00:13:59,444 --> 00:14:02,612 And then we created these spectacular little Gaur embryos, 218 00:14:02,614 --> 00:14:04,681 and we shipped them off to Iowa, 219 00:14:04,683 --> 00:14:07,017 where they were implanted into an ordinary cow. 220 00:14:07,019 --> 00:14:08,785 And it turns out that, 10 months later, 221 00:14:08,787 --> 00:14:12,022 we had this beautiful little baby Gaur that was born. 222 00:14:12,024 --> 00:14:14,457 It looked like a little baby reindeer -- just adorable. 223 00:14:14,459 --> 00:14:19,996 But where Bob sees beauty, others see monstrosity. 224 00:14:19,998 --> 00:14:23,800 Opponents of cloning say he's playing God. 225 00:14:23,802 --> 00:14:26,736 Bob doesn't see it that way. 226 00:14:26,738 --> 00:14:29,305 Cloning really isn't all that unusual. 227 00:14:29,307 --> 00:14:32,442 For thousands of years, people have been cloning plants. 228 00:14:32,444 --> 00:14:35,745 You can actually start by taking a clipping from a plant -- 229 00:14:35,747 --> 00:14:38,515 you get some of the genetic material -- 230 00:14:38,517 --> 00:14:42,185 and then add a little nutrients... 231 00:14:44,388 --> 00:14:45,622 ...get it to root, 232 00:14:45,624 --> 00:14:49,225 and to basically clone an entire new organism. 233 00:14:50,561 --> 00:14:54,064 Humanity has mastered the cloning of plants, 234 00:14:54,066 --> 00:14:57,700 and we are now working our way through the animal kingdom. 235 00:14:57,702 --> 00:15:00,870 Could we someday take the DNA of dead people 236 00:15:00,872 --> 00:15:03,039 and bring their bodies back to life? 237 00:15:03,041 --> 00:15:06,943 Can we cultivate a garden of resurrected humans? 238 00:15:09,748 --> 00:15:11,748 Imagine a world 239 00:15:11,750 --> 00:15:14,584 where a woman could bring back her deceased husband 240 00:15:14,586 --> 00:15:16,920 by giving birth to him... 241 00:15:16,922 --> 00:15:19,089 or a man could bring back his mother 242 00:15:19,091 --> 00:15:21,891 and raise her as his daughter. 243 00:15:21,893 --> 00:15:24,894 If we have a living cell of a dead person, 244 00:15:24,896 --> 00:15:28,264 certainly, we could, in theory, clone that individual. 245 00:15:28,266 --> 00:15:31,101 We published a paper about a year or two ago 246 00:15:31,103 --> 00:15:34,471 where we show we can actually now create human embryos 247 00:15:34,473 --> 00:15:38,208 that are genetically identical to a normal embryo. 248 00:15:38,210 --> 00:15:40,210 The only way you would really know 249 00:15:40,212 --> 00:15:42,345 whether you could clone a human being 250 00:15:42,347 --> 00:15:44,347 is to actually implant that embryo 251 00:15:44,349 --> 00:15:46,516 into the uterus of a surrogate mother. 252 00:15:46,518 --> 00:15:47,984 Of course, we cannot implant those -- 253 00:15:47,986 --> 00:15:49,419 that would be considered unethical -- 254 00:15:49,421 --> 00:15:51,087 so it's unclear whether or not they would -- 255 00:15:51,089 --> 00:15:52,322 would give rise to a human being. 256 00:15:53,657 --> 00:15:59,629 Society has vehemently rejected reproductive human cloning. 257 00:15:59,631 --> 00:16:02,832 In this climate, it is extremely difficult 258 00:16:02,834 --> 00:16:07,370 for geneticists to obtain funding for their research. 259 00:16:07,372 --> 00:16:10,240 There is also a shortage of material. 260 00:16:10,242 --> 00:16:12,575 So, one of the problems with human cloning 261 00:16:12,577 --> 00:16:13,676 is the supply of eggs. 262 00:16:13,678 --> 00:16:15,078 So, with a mouse or a cow, 263 00:16:15,080 --> 00:16:17,914 we can get literally hundreds, if not thousands, of eggs. 264 00:16:17,916 --> 00:16:19,916 We can go to the slaughterhouse, for instance, 265 00:16:19,918 --> 00:16:21,217 and get them for a dollar each 266 00:16:21,219 --> 00:16:22,852 and get thousands of these cow eggs. 267 00:16:22,854 --> 00:16:26,823 With the humans, it took us over a year just to get five eggs. 268 00:16:26,825 --> 00:16:29,125 Even if you had the eggs, 269 00:16:29,127 --> 00:16:31,528 it could take hundreds of pregnancies 270 00:16:31,530 --> 00:16:34,097 to perfect human cloning, 271 00:16:34,099 --> 00:16:35,532 a process that could result 272 00:16:35,534 --> 00:16:39,936 in scores of babies with horrific genetic damage. 273 00:16:39,938 --> 00:16:41,237 It'd be very much like -- 274 00:16:41,239 --> 00:16:43,239 if you wanted to clone your child, 275 00:16:43,241 --> 00:16:45,275 it'd be like sending him up in a rocket 276 00:16:45,277 --> 00:16:47,177 with a 50-50 chance it would blow up. 277 00:16:47,179 --> 00:16:52,482 In most of the world, cloning humans is not illegal. 278 00:16:52,484 --> 00:16:57,754 One day, a rogue scientist will pull it off. 279 00:16:57,756 --> 00:17:04,294 But cloning a person is not the same as duplicating a person. 280 00:17:06,864 --> 00:17:09,432 A lot of people, you know, who have their pets -- 281 00:17:09,434 --> 00:17:12,035 they want to often clone them, and they want Fluffy back. 282 00:17:12,037 --> 00:17:14,571 And what I tell them is, "you're not gonna get Fluffy back." 283 00:17:14,573 --> 00:17:17,640 As a matter of fact, we actually clone entire herds of cows 284 00:17:17,642 --> 00:17:19,876 from a single cell from the same animal, 285 00:17:19,878 --> 00:17:21,811 and they develop a whole hierarchy, 286 00:17:21,813 --> 00:17:23,213 just like we do in humans. 287 00:17:23,215 --> 00:17:25,515 So you have timid cows and aggressive cows, 288 00:17:25,517 --> 00:17:26,749 and they're all clones. 289 00:17:26,751 --> 00:17:29,085 So they develop their own behavioral patters. 290 00:17:29,087 --> 00:17:30,320 So the environment 291 00:17:30,322 --> 00:17:33,923 has a very profound impact on your development. 292 00:17:33,925 --> 00:17:38,962 Let's say we decide to take DNA from Einstein's hair 293 00:17:38,964 --> 00:17:42,031 and grow some new Einsteins. 294 00:17:42,033 --> 00:17:47,337 Those clones would not be the man who wrote "E = MC squared." 295 00:17:47,339 --> 00:17:49,806 Each would have a unique personality 296 00:17:49,808 --> 00:17:52,041 shaped by his environment. 297 00:17:53,511 --> 00:17:59,015 Clones are like identical twins born years apart -- 298 00:17:59,017 --> 00:18:04,954 they may be similar, but they will not be the same. 299 00:18:04,956 --> 00:18:07,690 Perhaps the key to life after death 300 00:18:07,692 --> 00:18:10,426 is not to grow an entirely new body, 301 00:18:10,428 --> 00:18:12,528 but to resurrect the one you have. 302 00:18:16,581 --> 00:18:19,983 At the moment, our society does not permit human cloning, 303 00:18:21,861 --> 00:18:23,828 but that could change. 304 00:18:23,830 --> 00:18:25,563 In the meantime, 305 00:18:25,565 --> 00:18:29,800 biotechnologists have another trick up their sleeves -- 306 00:18:29,802 --> 00:18:33,637 resurrecting people piece by piece. 307 00:18:33,639 --> 00:18:37,708 It's an approach that could transform medical science 308 00:18:37,710 --> 00:18:42,613 and blur the line between life and death. 309 00:18:42,615 --> 00:18:45,750 The revolution begins here, 310 00:18:45,752 --> 00:18:48,919 in a laboratory the University of Minnesota. 311 00:18:48,921 --> 00:18:52,289 This is where Dr. Doris Taylor 312 00:18:52,291 --> 00:18:55,493 breathes life back into the dead. 313 00:18:55,495 --> 00:18:57,862 I just want to change the world. 314 00:18:57,864 --> 00:19:00,564 I want to change the world for people with disease. 315 00:19:00,566 --> 00:19:03,401 I also have a brother who's chronically ill, 316 00:19:03,403 --> 00:19:07,271 and that's probably influenced everything I've done in my life. 317 00:19:07,273 --> 00:19:11,275 Doris is changing the world by growing new body parts 318 00:19:11,277 --> 00:19:13,544 from the shells of old ones. 319 00:19:13,546 --> 00:19:17,615 She takes organs from cadavers and reanimates them 320 00:19:17,617 --> 00:19:23,220 using a method drawn from an unlikely source -- architecture. 321 00:19:28,860 --> 00:19:30,528 The bricks in a building 322 00:19:30,530 --> 00:19:33,030 are just like the cells in an organ -- 323 00:19:33,032 --> 00:19:35,299 different kinds, different shapes. 324 00:19:35,301 --> 00:19:36,801 And they make rooms, 325 00:19:36,803 --> 00:19:40,171 and the rooms are like the chambers of a heart. 326 00:19:40,173 --> 00:19:43,674 They're connected by doorways, like the valves. 327 00:19:43,676 --> 00:19:46,377 They have hallways, like the arteries and veins. 328 00:19:46,379 --> 00:19:49,380 Essentially, you can think of an organ 329 00:19:49,382 --> 00:19:51,882 just like you think of a building. 330 00:19:52,818 --> 00:19:57,054 Just as buildings can be rebuilt brick by brick, 331 00:19:57,056 --> 00:20:01,759 Doris believes bodies can be rebuilt cell by cell. 332 00:20:01,761 --> 00:20:05,362 In building construction, they use a scaffold that -- 333 00:20:05,364 --> 00:20:06,864 like you see here -- 334 00:20:06,866 --> 00:20:12,069 to essentially provide access to otherwise inaccessible areas 335 00:20:12,071 --> 00:20:15,673 and to create a framework for what they're gonna build. 336 00:20:15,675 --> 00:20:19,510 We essentially do the same thing in the laboratory with an organ. 337 00:20:19,512 --> 00:20:22,480 We create a framework on which we can put cells. 338 00:20:22,482 --> 00:20:27,518 Doris reanimates major organs, 339 00:20:27,520 --> 00:20:31,489 including livers, lungs, and hearts. 340 00:20:34,092 --> 00:20:36,494 This is a ghost heart. 341 00:20:36,496 --> 00:20:40,030 This is essentially the framework, or scaffold, 342 00:20:40,032 --> 00:20:41,899 on which the cells sit. 343 00:20:41,901 --> 00:20:45,002 And by washing out all the cells, 344 00:20:45,004 --> 00:20:47,705 what we have left is a scaffold 345 00:20:47,707 --> 00:20:52,743 that we can repopulate with cells to now build a new organ. 346 00:20:52,745 --> 00:20:56,780 So, essentially, this scaffold is what tells cells 347 00:20:56,782 --> 00:21:00,150 how to join together and become a heart. 348 00:21:02,354 --> 00:21:04,855 What happens when you put fresh cells 349 00:21:04,857 --> 00:21:07,858 into a decellularized heart? 350 00:21:09,294 --> 00:21:13,297 This -- a modern miracle. 351 00:21:14,332 --> 00:21:17,101 Right now, if you need a body part, 352 00:21:17,103 --> 00:21:20,538 you face the grim prospect of organ rejection, 353 00:21:20,540 --> 00:21:25,709 but Doris' replacement organs -- heart, kidneys, and livers -- 354 00:21:25,711 --> 00:21:28,879 will be tailor-made for your body. 355 00:21:28,881 --> 00:21:33,517 We'll take an organ from a pig, strip all the cells, 356 00:21:33,519 --> 00:21:36,520 take your stem cells, put them in that organ, 357 00:21:36,522 --> 00:21:39,089 and build something that matches you. 358 00:21:39,091 --> 00:21:41,792 So, if Doris and her team 359 00:21:41,794 --> 00:21:44,929 can bring hearts and livers back from the dead, 360 00:21:44,931 --> 00:21:48,599 could they also reanimate a human brain? 361 00:21:48,601 --> 00:21:53,203 Now, could we build a cluster of neurons 362 00:21:53,205 --> 00:21:54,672 and glial cells 363 00:21:54,674 --> 00:21:58,576 and everything that looks like part of a brain or a brain? 364 00:21:58,578 --> 00:22:02,613 I have no doubt that, one day, we'll be able to do that. 365 00:22:02,615 --> 00:22:08,586 Can we resurrect you and who you are -- your personality? 366 00:22:08,588 --> 00:22:11,322 I don't think we know how to do that yet. 367 00:22:11,324 --> 00:22:15,159 It's more likely this technology will be used 368 00:22:15,161 --> 00:22:17,995 to replace damaged sections of the brain, 369 00:22:17,997 --> 00:22:22,399 perhaps even extending its life beyond the rest of the body. 370 00:22:22,401 --> 00:22:26,403 But can we go even further? 371 00:22:26,405 --> 00:22:31,041 As we die, could we have our brains transplanted 372 00:22:31,043 --> 00:22:34,178 into healthy donor bodies? 373 00:22:36,415 --> 00:22:40,584 I suspect the biggest challenge to a brain transplant 374 00:22:40,586 --> 00:22:43,621 is keeping it alive 375 00:22:43,623 --> 00:22:49,760 during the time of removing it from an individual 376 00:22:49,762 --> 00:22:54,298 and all the connections that would have to be recapitulated 377 00:22:54,300 --> 00:22:56,500 in a transplanted individual, 378 00:22:56,502 --> 00:22:58,369 because unlike the heart, 379 00:22:58,371 --> 00:23:00,371 it's not just about hooking up the blood supply. 380 00:23:00,373 --> 00:23:04,675 It'd also be about hooking up the spinal cord, 381 00:23:04,677 --> 00:23:07,111 hooking up all the nerves. 382 00:23:07,113 --> 00:23:12,149 I can't imagine how we could make all those connections 383 00:23:12,151 --> 00:23:16,186 in a timely way that maintain function. 384 00:23:16,188 --> 00:23:20,924 But do we even need to have physical brains? 385 00:23:22,360 --> 00:23:24,762 The key to resurrection 386 00:23:24,764 --> 00:23:28,432 is to restore what fundamentally makes us unique -- 387 00:23:28,434 --> 00:23:31,402 the contents of our minds. 388 00:23:31,404 --> 00:23:35,572 As technology advances, the prospect of copying our brains 389 00:23:35,574 --> 00:23:38,042 becomes more and more likely. 390 00:23:38,044 --> 00:23:42,012 Bringing the dead back to life may just be a matter 391 00:23:42,014 --> 00:23:46,116 of combining the right zeroes and ones. 392 00:23:49,998 --> 00:23:53,367 Our lives are continually monitored by technology. 393 00:23:54,802 --> 00:23:59,639 Almost everything we do leaves a digital trail. 394 00:23:59,641 --> 00:24:02,174 This immense library of information 395 00:24:02,176 --> 00:24:05,578 may still exist long after we die. 396 00:24:05,580 --> 00:24:10,249 If we gathered up a lifetime of these digital footprints, 397 00:24:10,251 --> 00:24:15,254 could we use them to bring someone back from the dead? 398 00:24:20,394 --> 00:24:21,861 These students 399 00:24:21,863 --> 00:24:25,631 could be the first humans to rise from the dead. 400 00:24:25,633 --> 00:24:30,002 They call themselves extreme lifeloggers. 401 00:24:30,004 --> 00:24:34,907 And they are digitally archiving their existence. 402 00:24:36,176 --> 00:24:40,813 Everything they see and hear, wherever they go, 403 00:24:40,815 --> 00:24:44,317 whomever they are with, how fast their hearts beat, 404 00:24:44,319 --> 00:24:46,686 even how much they sweat -- 405 00:24:46,688 --> 00:24:50,022 it's all recorded onto hard drives 406 00:24:50,024 --> 00:24:52,325 at Dublin City University. 407 00:24:52,327 --> 00:24:53,492 This is the brainchild 408 00:24:53,494 --> 00:24:58,264 of search-engine specialist Cathal Gurrin. 409 00:24:58,266 --> 00:25:00,633 Hey, how did it go? Pretty well. 410 00:25:00,635 --> 00:25:01,867 It was fun. 411 00:25:01,869 --> 00:25:03,936 How about the weather -- was it cold? Bit cold. 412 00:25:03,938 --> 00:25:06,072 You got the devices. We can have a look? Yes. 413 00:25:06,074 --> 00:25:08,541 Accelerometer. Yes, accelerometer. 414 00:25:08,543 --> 00:25:10,276 Here is mine. Oh, thank you. 415 00:25:10,278 --> 00:25:12,211 And the camera. Camera. Great. 416 00:25:12,213 --> 00:25:13,946 Thanks. Let's have a look. 417 00:25:13,948 --> 00:25:19,285 Cathal has recorded his own life for 5 1/2 years. 418 00:25:19,287 --> 00:25:21,554 So far, he has gathered 419 00:25:21,556 --> 00:25:26,459 over 8 1/2 million images and sensor readings. 420 00:25:26,461 --> 00:25:29,128 So here's, for example, a typical day in my life -- 421 00:25:29,130 --> 00:25:30,396 on the 10th of November. 422 00:25:30,398 --> 00:25:32,732 Here you can see what I did on that day. 423 00:25:32,734 --> 00:25:35,167 I got up in the morning. I made breakfast. 424 00:25:35,169 --> 00:25:36,402 I went to my office. 425 00:25:36,404 --> 00:25:39,505 I worked pretty much all of the day, with a coffee break, 426 00:25:39,507 --> 00:25:41,240 and then, driving home at night, 427 00:25:41,242 --> 00:25:43,175 going by a restaurant on the way. 428 00:25:43,177 --> 00:25:44,510 The software we have 429 00:25:44,512 --> 00:25:48,481 has managed to take about 3,000 pictures on that day 430 00:25:48,483 --> 00:25:50,282 and summarized them down 431 00:25:50,284 --> 00:25:52,585 into this collection of about 30 pictures. 432 00:25:52,587 --> 00:25:57,690 Cathal is creating an auxiliary memory -- 433 00:25:57,692 --> 00:25:59,558 something that can be searched 434 00:25:59,560 --> 00:26:02,528 when his biological memory fails him, 435 00:26:02,530 --> 00:26:08,934 preserved in a medium far more accurate than the human brain. 436 00:26:08,936 --> 00:26:10,803 When you're faced with this kind of data 437 00:26:10,805 --> 00:26:12,738 about your life -- your life in the past -- 438 00:26:12,740 --> 00:26:15,741 then you start to identify times you make mistakes in your memory. 439 00:26:15,743 --> 00:26:16,876 It becomes very apparent 440 00:26:16,878 --> 00:26:18,677 when you remember an event in the past 441 00:26:18,679 --> 00:26:21,480 and you go back to look at it -- the differences in the reality 442 00:26:21,482 --> 00:26:23,215 versus what you actually see itself. 443 00:26:23,217 --> 00:26:25,384 And that's where a life log can really help you 444 00:26:25,386 --> 00:26:27,887 to identify the truth about what's happened in the past, 445 00:26:27,889 --> 00:26:29,655 not just your memory's version of it, 446 00:26:29,657 --> 00:26:32,691 which we know, from research, that we'll have inaccuracies -- 447 00:26:32,693 --> 00:26:34,627 we'll have flaws in that memory. 448 00:26:36,229 --> 00:26:39,799 Anyone who's spent time on social-networking sites 449 00:26:39,801 --> 00:26:42,067 knows that a basic form of lifelogging 450 00:26:42,069 --> 00:26:45,671 is already practiced by millions of people, 451 00:26:45,673 --> 00:26:48,641 anxious to share their every passing thought, 452 00:26:48,643 --> 00:26:50,743 no matter how trivial. 453 00:26:50,745 --> 00:26:53,312 It's estimated 454 00:26:53,314 --> 00:26:57,383 that humanity today generates more data in two days 455 00:26:57,385 --> 00:27:03,856 than it produced in all of history up to the year 2003. 456 00:27:03,858 --> 00:27:08,494 And this data stream is expected to increase exponentially 457 00:27:08,496 --> 00:27:09,895 in the future. 458 00:27:09,897 --> 00:27:11,864 Extreme lifelogging will add 459 00:27:11,866 --> 00:27:14,400 an enormous amount of new imagery and data 460 00:27:14,402 --> 00:27:18,838 to the vast amount that already floods the Internet. 461 00:27:18,840 --> 00:27:20,372 We will typically capture 462 00:27:20,374 --> 00:27:23,042 at least a million photographs a year for an individual person. 463 00:27:23,044 --> 00:27:25,110 So that's an incredibly huge data set 464 00:27:25,112 --> 00:27:27,012 to be handled by a search engine. 465 00:27:27,014 --> 00:27:29,482 And that's one of the issues about lifelogging 466 00:27:29,484 --> 00:27:31,984 that we are trying to solve in this research -- 467 00:27:31,986 --> 00:27:34,487 how to handle a million photographs a year for people, 468 00:27:34,489 --> 00:27:37,122 how to handle many hundreds of millions of sensor values, 469 00:27:37,124 --> 00:27:40,292 make sense of this, organize this, 470 00:27:40,294 --> 00:27:43,496 and take this enormous quantity of big, big data about people 471 00:27:43,498 --> 00:27:47,800 and make it useable and easy for the people 472 00:27:47,802 --> 00:27:50,269 to access their content from within that archive. 473 00:27:50,271 --> 00:27:52,371 Cathal and his students 474 00:27:52,373 --> 00:27:54,273 are creating backup drives 475 00:27:54,275 --> 00:27:57,977 for their entire life's experience -- 476 00:27:57,979 --> 00:28:00,946 black boxes of the mind. 477 00:28:00,948 --> 00:28:05,518 Someday, we might all have these personal life recorders -- 478 00:28:05,520 --> 00:28:08,254 initially, to enhance our memories, 479 00:28:08,256 --> 00:28:13,359 but after death, our survivors could take our black boxes 480 00:28:13,361 --> 00:28:17,029 and hand them over for uploading. 481 00:28:17,031 --> 00:28:18,964 Essentially, memory defines us. 482 00:28:18,966 --> 00:28:20,599 A person's personality is based 483 00:28:20,601 --> 00:28:22,968 on their memories and their experiences over time. 484 00:28:22,970 --> 00:28:25,104 By gathering all this type of data, 485 00:28:25,106 --> 00:28:27,940 we're able to hopefully, in the future, re-create 486 00:28:27,942 --> 00:28:30,743 that person's personality in the digital memory. 487 00:28:30,745 --> 00:28:32,678 We're able to re-create how that person reacts 488 00:28:32,680 --> 00:28:34,413 to a certain stimulus in the environment, 489 00:28:34,415 --> 00:28:36,715 how that person reacts to interactions with other people. 490 00:28:36,717 --> 00:28:38,984 We'd be able to take the digital memory data 491 00:28:38,986 --> 00:28:41,253 and by enhancing our artificial-intelligence 492 00:28:41,255 --> 00:28:43,355 algorithms and search engines right now, 493 00:28:43,357 --> 00:28:44,757 be able to re-create 494 00:28:44,759 --> 00:28:47,793 a fairly good representation of that person's personality 495 00:28:47,795 --> 00:28:49,261 from the digital memory. 496 00:28:49,263 --> 00:28:53,632 This would not create a perfect mirror of the mind, 497 00:28:53,634 --> 00:28:57,903 but it would reflect the stuff our minds are attracted to. 498 00:28:57,905 --> 00:29:01,707 A computer algorithm would sort through your likes and dislikes 499 00:29:01,709 --> 00:29:06,545 and extrapolate a personality based on your experiences. 500 00:29:07,948 --> 00:29:10,316 Cathal's route to resurrection 501 00:29:10,318 --> 00:29:13,285 might bring something similar to you back to life. 502 00:29:13,287 --> 00:29:19,425 But is there a way to exactly re-create your inner self? 503 00:29:19,427 --> 00:29:22,461 This man says yes. 504 00:29:23,396 --> 00:29:27,299 We just need the right tools for the job. 505 00:29:31,259 --> 00:29:33,894 Your mind is the product 506 00:29:33,896 --> 00:29:38,966 of 100 trillion neural connections in your brain. 507 00:29:38,968 --> 00:29:42,936 This dense pattern is you. 508 00:29:42,938 --> 00:29:47,407 And when the brain dies, you die. 509 00:29:47,409 --> 00:29:50,644 What if we could separate the contents of our minds 510 00:29:50,646 --> 00:29:53,046 from our brains? 511 00:29:53,048 --> 00:29:56,283 If we could pull the essence of who you are 512 00:29:56,285 --> 00:29:59,319 out of the fragile biology of your brain 513 00:29:59,321 --> 00:30:01,989 and put it into another container, 514 00:30:01,991 --> 00:30:05,359 you could live again. 515 00:30:09,097 --> 00:30:12,966 By day, Ken Hayworth is a neuroscientist 516 00:30:12,968 --> 00:30:16,603 at a prestigious Massachusetts University. 517 00:30:16,605 --> 00:30:20,640 In his off hours, he runs the Brain Preservation Foundation, 518 00:30:20,642 --> 00:30:25,012 which looks for ways to resurrect our minds after death. 519 00:30:25,014 --> 00:30:28,515 I want to see the future, and death is preventing that. 520 00:30:28,517 --> 00:30:33,387 But if we can preserve and map our brains, we can get there. 521 00:30:40,328 --> 00:30:43,897 The wiring of your brain is like this train track, 522 00:30:43,899 --> 00:30:47,100 only the total length of wires in your brain 523 00:30:47,102 --> 00:30:49,803 is actually billions of times longer 524 00:30:49,805 --> 00:30:52,406 than the length of this toy track. 525 00:30:52,408 --> 00:30:55,342 And the number of switching points in your brain 526 00:30:55,344 --> 00:30:58,311 numbers in the hundreds of trillions. 527 00:31:00,548 --> 00:31:04,051 We call this set of wires and switches in a human brain 528 00:31:04,053 --> 00:31:05,719 the connectome. 529 00:31:05,721 --> 00:31:08,588 The connectome is the seat of all of our memory, 530 00:31:08,590 --> 00:31:14,728 and it is the generator of our thought and our consciousness. 531 00:31:14,730 --> 00:31:19,299 If we could copy this set of trillions of connections, 532 00:31:19,301 --> 00:31:26,173 we could re-create you, even after your body has died. 533 00:31:26,175 --> 00:31:28,975 The way to rescue 534 00:31:28,977 --> 00:31:33,880 all the information held in the connectome, Ken says, 535 00:31:33,882 --> 00:31:37,584 is to treat the brain like a computer. 536 00:31:37,586 --> 00:31:39,853 So, this is a dead computer. 537 00:31:39,855 --> 00:31:41,621 It's way out of date. 538 00:31:41,623 --> 00:31:43,757 It has a burned-out motherboard, 539 00:31:43,759 --> 00:31:46,960 and there's really essentially nothing I can do 540 00:31:46,962 --> 00:31:48,962 to repair this computer. 541 00:31:48,964 --> 00:31:52,799 And I'm really sad about that, because this particular computer 542 00:31:52,801 --> 00:31:55,702 has all my wedding photographs, my PhD thesis, 543 00:31:55,704 --> 00:31:57,637 and I'm going to just toss it 544 00:31:57,639 --> 00:32:00,140 into the trash and lose it forever. 545 00:32:00,142 --> 00:32:02,242 But, of course, that's not true. 546 00:32:02,244 --> 00:32:04,044 Those pieces of information 547 00:32:04,046 --> 00:32:06,813 are stored digitally on this hard drive, 548 00:32:06,815 --> 00:32:11,485 and I can copy that information onto another hard drive. 549 00:32:11,487 --> 00:32:16,389 Now, what I'm saying is that neuroscience has told us 550 00:32:16,391 --> 00:32:19,059 that we, in essence, are digital information 551 00:32:19,061 --> 00:32:22,829 stored in the synaptic connections within our brain. 552 00:32:22,831 --> 00:32:25,799 If we preserve that brain at our death, 553 00:32:25,801 --> 00:32:29,569 then that information that makes us unique -- 554 00:32:29,571 --> 00:32:32,506 all of those memories -- they're not lost, 555 00:32:32,508 --> 00:32:35,108 and they can be potentially brought back 556 00:32:35,110 --> 00:32:38,612 just the same way digital information can be brought back 557 00:32:38,614 --> 00:32:40,780 by putting it in a new computer. 558 00:32:40,782 --> 00:32:45,719 Software is physically written onto a hard drive. 559 00:32:45,721 --> 00:32:48,388 Make an exact copy of a drive, 560 00:32:48,390 --> 00:32:53,193 and you have an exact copy of the information it contains. 561 00:32:53,195 --> 00:32:56,863 Ken believes all the information in your brain 562 00:32:56,865 --> 00:32:58,832 can also be copied and stored. 563 00:32:58,834 --> 00:33:01,168 All you have to do to preserve 564 00:33:01,170 --> 00:33:03,503 the connectome's trillions of neural connections 565 00:33:03,505 --> 00:33:05,472 is to copy the brain's hardware... 566 00:33:07,642 --> 00:33:09,509 ...one slice at a time. 567 00:33:09,511 --> 00:33:13,947 Ken's brain-scanning assembly line would work like this. 568 00:33:13,949 --> 00:33:15,916 At the moment of death, 569 00:33:15,918 --> 00:33:20,253 the brain is extracted and preserved in plastic. 570 00:33:20,255 --> 00:33:24,524 The brain is then chopped by a heated diamond knife 571 00:33:24,526 --> 00:33:31,131 into 20-micron cubes 40,000 times thinner than a human hair. 572 00:33:31,133 --> 00:33:35,902 These tiny slices are sliced again, 1,000 times thinner, 573 00:33:35,904 --> 00:33:39,506 then scanned by ion beams. 574 00:33:39,508 --> 00:33:42,842 The process is repeated millions of times 575 00:33:42,844 --> 00:33:45,745 until the entire brain is digitized. 576 00:33:45,747 --> 00:33:47,480 Hmm? Hmm? 577 00:33:47,482 --> 00:33:50,550 It is technology that exists today. 578 00:33:50,552 --> 00:33:53,853 We mapped small bits of neural tissue 579 00:33:53,855 --> 00:33:56,823 at this ultimate resolution already. 580 00:33:56,825 --> 00:33:58,959 The resolution is so high 581 00:33:58,961 --> 00:34:03,330 that we cannot only see the connections between neurons -- 582 00:34:03,332 --> 00:34:07,534 we can also determine their strength and type. 583 00:34:07,536 --> 00:34:11,504 Once we have the ability to map a human brain 584 00:34:11,506 --> 00:34:14,040 and once we have the knowledge 585 00:34:14,042 --> 00:34:17,210 of how that generates a human mind, 586 00:34:17,212 --> 00:34:23,984 we will be able to simulate that brain in a computer substrate 587 00:34:23,986 --> 00:34:28,722 and bring that individual back to life 588 00:34:28,724 --> 00:34:31,825 inside of a computer simulation. 589 00:34:31,827 --> 00:34:34,761 Mapping the human mind today 590 00:34:34,763 --> 00:34:39,599 would require an enormously expensive Apollo-sized project. 591 00:34:39,601 --> 00:34:44,237 But as technology gets cheaper, that could change. 592 00:34:44,239 --> 00:34:48,375 So, whereas it's tens of billions of dollars today 593 00:34:48,377 --> 00:34:50,210 to map a whole human mind, 594 00:34:50,212 --> 00:34:54,714 it will be thousands of dollars 100 years from now. 595 00:34:54,716 --> 00:34:59,619 Anybody that wants to get to that future technology 596 00:34:59,621 --> 00:35:03,490 just 100 years from now can get their brain preserved. 597 00:35:03,492 --> 00:35:08,662 Imagine the future in which every hospital is equipped 598 00:35:08,664 --> 00:35:11,798 to preserve your brain if you dip near death. 599 00:35:11,800 --> 00:35:16,069 Thousands of brains, sliced and scanned, 600 00:35:16,071 --> 00:35:20,507 will be ready to form a new population of the formerly dead. 601 00:35:20,509 --> 00:35:22,942 That person's brain 602 00:35:22,944 --> 00:35:25,412 that's sitting there on the shelf for the last 100 years 603 00:35:25,414 --> 00:35:29,215 can be taken off, sliced, imaged, 604 00:35:29,217 --> 00:35:32,619 and downloaded into a computer simulation. 605 00:35:32,621 --> 00:35:37,824 And that person wakes up like they were in a long sleep. 606 00:35:39,593 --> 00:35:46,132 And if we live on as digital copies of ourselves, what then? 607 00:35:46,134 --> 00:35:49,602 What would life be like as a computer program? 608 00:35:49,604 --> 00:35:52,238 How would we relate to each other? 609 00:35:52,240 --> 00:35:56,343 Could we bear to live without physical sensation? 610 00:35:58,145 --> 00:35:59,646 To bring back a brain 611 00:35:59,648 --> 00:36:02,148 and just leave it in some computer 612 00:36:02,150 --> 00:36:05,185 without legs, without arms, without eyes -- 613 00:36:05,187 --> 00:36:09,656 of course, that would be an experience worse than death. 614 00:36:09,658 --> 00:36:13,460 Resurrecting the mind may not be enough. 615 00:36:13,462 --> 00:36:17,030 To truly live again, we will want to see the world around us 616 00:36:17,032 --> 00:36:18,898 and touch the ones we love. 617 00:36:18,900 --> 00:36:22,602 The challenges of restoring a mind to a biological body 618 00:36:22,604 --> 00:36:24,738 seem insurmountable. 619 00:36:24,740 --> 00:36:28,007 But there is another option. 620 00:36:28,009 --> 00:36:30,477 Perhaps we could build new bodies 621 00:36:30,479 --> 00:36:33,380 to carry our resurrected minds -- 622 00:36:33,382 --> 00:36:37,684 robot bodies, like these. 623 00:36:41,933 --> 00:36:46,069 Someday, we may be able to preserve our minds, 624 00:36:46,071 --> 00:36:48,972 but our resurrection will be incomplete 625 00:36:48,974 --> 00:36:50,841 if we don't have bodies -- 626 00:36:50,843 --> 00:36:53,543 not these fragile bags of chemicals, 627 00:36:53,545 --> 00:36:56,980 but perfect replicas of ourselves that never age 628 00:36:56,982 --> 00:36:59,683 and can be constantly upgraded -- 629 00:36:59,685 --> 00:37:04,654 robot vessels to carry our digitized minds. 630 00:37:04,656 --> 00:37:06,656 Think of it. 631 00:37:17,835 --> 00:37:22,606 In Japan, robots are a part of daily life. 632 00:37:22,608 --> 00:37:24,307 Most of them work in factories 633 00:37:24,309 --> 00:37:28,044 and don't look too different from the machines they build. 634 00:37:28,046 --> 00:37:32,149 But Japan also leads the world in building androids 635 00:37:32,151 --> 00:37:36,453 that straddle the line between humans and machines. 636 00:37:38,589 --> 00:37:42,526 If Hiroshi Ishiguro has his way, the world of the future 637 00:37:42,528 --> 00:37:45,695 will be filled with replicants so realistic, 638 00:37:45,697 --> 00:37:49,933 you can't tell them apart from flesh-and-blood people. 639 00:38:06,717 --> 00:38:12,756 Hiroshi's lab tests how much or how little humanity 640 00:38:12,758 --> 00:38:17,727 androids need to be accepted by humans. 641 00:38:17,729 --> 00:38:20,897 They have produced a line of robots 642 00:38:20,899 --> 00:38:22,899 ranging from near human 643 00:38:22,901 --> 00:38:26,903 to these almost impressionistic creatures. 644 00:38:41,853 --> 00:38:44,588 The Elfoid robots have a bare minimum 645 00:38:44,590 --> 00:38:46,089 of human characteristics, 646 00:38:46,091 --> 00:38:49,493 yet people are able to relate to them. 647 00:38:49,495 --> 00:38:53,997 In the future, this might be the low-budget option 648 00:38:53,999 --> 00:38:55,899 for your robot body. 649 00:38:55,901 --> 00:38:59,369 It's simple, but it does the job. 650 00:39:01,273 --> 00:39:04,407 For now, the Elfoid is remote-controlled, 651 00:39:04,409 --> 00:39:07,077 like all of Hiroshi's robots. 652 00:39:07,079 --> 00:39:10,981 Software reads the facial expressions of the operator 653 00:39:10,983 --> 00:39:13,884 and transmits them to tiny actuators 654 00:39:13,886 --> 00:39:16,987 under the android's synthetic skin. 655 00:39:16,989 --> 00:39:21,191 These mimic human facial muscles. 656 00:39:29,233 --> 00:39:33,470 At the other end of the ladder are the Geminoids, 657 00:39:33,472 --> 00:39:36,673 meant to mirror humans as closely as possible. 658 00:39:36,675 --> 00:39:40,977 The Geminoids are replicas of real people. 659 00:39:40,979 --> 00:39:44,314 Imagine a body like this 660 00:39:44,316 --> 00:39:48,585 loaded with the contents of your digitized mind, 661 00:39:48,587 --> 00:39:50,954 or perhaps your disembodied consciousness 662 00:39:50,956 --> 00:39:53,557 would operate the android from a mainframe, 663 00:39:53,559 --> 00:39:58,094 just as these robots are controlled from a distance. 664 00:39:58,096 --> 00:40:01,798 Hiroshi is already working on the technology 665 00:40:01,800 --> 00:40:07,070 to connect our minds to the androids. 666 00:40:07,072 --> 00:40:08,505 If possible... 667 00:40:18,749 --> 00:40:23,053 If Hiroshi does perfect a brain/machine interface, 668 00:40:23,055 --> 00:40:26,590 he will probably first test it on himself -- 669 00:40:26,592 --> 00:40:31,394 or, more precisely, his replicant. 670 00:40:31,396 --> 00:40:33,730 Yeah, yeah. He's restarting -- restarting. 671 00:40:33,732 --> 00:40:34,931 Okay. 672 00:40:34,933 --> 00:40:36,833 Yeah, we have come -- we have come back now. 673 00:40:38,637 --> 00:40:39,669 Okay. 674 00:40:39,671 --> 00:40:41,638 Now it's okay. Can you look at me? 675 00:40:41,640 --> 00:40:43,540 Mm-hmm. All right. 676 00:40:43,542 --> 00:40:46,576 Hiroshi often sends his doppelganger to other countries 677 00:40:46,578 --> 00:40:48,011 to represent him 678 00:40:48,013 --> 00:40:52,749 or to teach classes that he's too busy to attend in the flesh. 679 00:40:52,751 --> 00:40:55,151 How do people respond to this and me? 680 00:40:55,153 --> 00:40:57,020 Well -- well, maybe they were -- 681 00:40:57,022 --> 00:40:59,923 in the first contact, they were a little bit nervous, 682 00:40:59,925 --> 00:41:01,157 but, you know, once -- 683 00:41:01,159 --> 00:41:03,493 as you know that, once you start to talk, 684 00:41:03,495 --> 00:41:06,963 they can concentrate on the -- in a conversation. 685 00:41:08,933 --> 00:41:14,337 Hiroshi has essentially created a robot version of himself, 686 00:41:14,339 --> 00:41:17,073 and the better his hardware gets, 687 00:41:17,075 --> 00:41:20,477 the more his androids pass for real people. 688 00:41:27,451 --> 00:41:30,687 The Geminoid "F" is an android so lifelike, 689 00:41:30,689 --> 00:41:33,356 it has performed onstage in plays, 690 00:41:33,358 --> 00:41:37,527 but its inventor is never satisfied. 691 00:41:47,505 --> 00:41:50,840 Thank you for answering my questions, Professor. 692 00:41:50,842 --> 00:41:52,375 You're welcome. 693 00:41:52,377 --> 00:41:55,745 This could be the future face of the living dead -- 694 00:41:55,747 --> 00:41:59,683 not decaying corpses, but smooth silicon flesh -- 695 00:41:59,685 --> 00:42:05,855 robots carrying the minds of our long-lost loved ones. 696 00:42:17,869 --> 00:42:24,841 The day when we never have to say goodbye may soon be at hand. 697 00:42:24,843 --> 00:42:28,945 But what would it be like to see your dead grandmother again, 698 00:42:28,947 --> 00:42:32,348 living inside a synthetic body? 699 00:42:32,350 --> 00:42:36,586 Would she still be the woman you knew? 700 00:42:36,588 --> 00:42:39,355 We won't know until it happens. 701 00:42:39,357 --> 00:42:41,858 The human race may one day be filled 702 00:42:41,860 --> 00:42:45,095 with new and unfamiliar ethnic groups. 703 00:42:45,097 --> 00:42:49,065 The people next door might be the robotic undead, 704 00:42:49,067 --> 00:42:51,835 and the great divide in society 705 00:42:51,837 --> 00:42:56,106 would be between those who have lived only once 706 00:42:56,108 --> 00:43:00,438 and those who are on their second or fifth body. 707 00:43:00,439 --> 00:43:04,439 == sync, corrected by elderman == 708 00:43:04,489 --> 00:43:09,039 Repair and Synchronization by Easy Subtitles Synchronizer 1.0.0.0 57707

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