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โชโช MARY SHELLEY IS THE VERY
FIRST WRITER OF SCIENCE FICTION.
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IN HER NOVEL "FRANKENSTEIN," AUTHOR MARY
SHELLEY DARED ASK QUESTIONS, CAN MAN CREATE LIFE
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IN A LABORATORY. IS IT A PROPHECY OF
MAN'S PROGRESS OR SCIENCE RUNNING
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AMOK? THE WORD FRANKENSTEIN
IMPLIES THE BEST INTENTIONS OF
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SCIENTISTS GO HAYWIRE AND
TECHNOLOGY FIGHTS BACK. IT'S ALIVE!
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IT'S ALIVE! TOMORROW
BEGINS THE SPARK OF IMAGINATION.
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THE FLASH OF INSIGHT THAT DEMOLISHES
YESTERDAY'S LIMITATIONS AND INSPIRES
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00:00:49,749 --> 00:00:57,749
TECHNOLOGIES TO CREATE NEW
WORLDS. I'M RIDLEY SCOTT AND
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THESE ARE "THE PROPHETS OF SCIENCE
FICTION." SUCH A GHASTLY TALE, A CREATURE
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MADE WITH DEAD MEAT, BOUND TOGETHER
WITH WIRE. AT THE TIME IT MUST HAVE BEEN
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UNTHINKABLE. UNSPEAKABLE.
UNSPEAKABLY HORRIBLE.
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FOR A TEENAGER WHO IS MARY SHELLEY TO WRITE
SUCH A NOVEL, ANYBODY AT THE TIME MUST HAVE
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WONDERED ABOUT HER SANITY. WAS THAT ONE
STROKE OF GENIUS IN A LIFE OF THAT MOMENT?
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BECAUSE IT IS EXTREME. Narrator:
GENEVA, SWITZERLAND, 1816, NOW KNOWN AS
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THE HAUNTED SUMMER, FRIENDS READ OLD GHOST
STORIES ALLOWED. TWO OF THEM ARE LORD BYRON AND
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00:01:49,676 --> 00:01:57,249
PERCY SHELLEY. BUT PERHAPS THE MOST
SIGNIFICANT OF THE GROUP IS AN 18-YEAR-OLD
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WOMAN NAMED MARY, SOON TO BECOME
SHELLEY'S WIFE. INSPIRED BY THEIR NIGHTLY
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RITUAL, LORD BYRON ISSUES A NOW INFAMOUS
CHALLENGE. A CONTEST TO DETERMINE WHO AMONG
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00:02:08,561 --> 00:02:14,032
THEM COULD PEN THE MOST
TERRIFYING STORY BY SUMMER'S END.
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YOUNG MARY IS EAGER TO PROVE HERSELF
THE LITERARY EQUAL OF HER GIFTED FRIENDS.
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I WAS FORCED TO REPLY WITH A MORTIFYING
NEGATIVE. Narrator: A FACT MADE ALL THE
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MORE FRUSTRATING IN LIGHT OF MARY'S FAMOUS
LINEAGE. MARY SHELLEY WAS THE DAUGHTER
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OF THE LEADING FEMINIST OF THE DAY, ALONG WITH
THE... ONE OF THE MOST FAMOUS PHILOSOPHERS OF
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THE DAY, WILLIAM GODWIN. AFTER SHE WAS BORN
HER MOTHER FAILED TO EXPEL THE PLACENTA,
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GOT FEVER, DIED 11 DAYS LATER. SO MARY WAS
LEFT MOTHERLESS. Narrator: MARY'S UPBRINGING
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AND EDUCATION ARE LEFT IN THE
HANDS OF HER FATHER, WILLIAM GODWIN.
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GODWIN ATTRACTED A CIRCLE OF THE LEADING
PHILOSOPHERS, SCIENTISTS, WRITERS, ARTISTS OF
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THE DAY. IT WAS A HOME THAT WAS
VERY, VERY RICH WITH... AS FAR AS
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INTELLECTUALS WENT. SO THEY WOULD BE
DISCUSSING THE ISSUES OF THE DAY, AND SHE
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LISTENED. AND SHE WAS
ALWAYS ALLOWED TO LISTEN.
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Narrator: MARY'S EDUCATION UNFOLDED DURING
A TIME OF UNPARALLELED ADVANCES IN HUMAN
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KNOWLEDGE. THE SCIENTIFIC REVOLUTION.
CONVERSATIONS OFTEN DRIFTED FROM
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GHOST STORIES TO THE FASCINATING NEW SCIENTIFIC
DISCOVERIES BEING MADE THAT FATEFUL SUMMER.
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THE TOPIC OF DISCUSSION ON THIS PARTICULAR
EVENING, AN ITALIAN PHYSICIST WHOSE CONTROVERSIAL
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EXPERIMENTS HAVE RECENTLY
MADE HEADLINES. LUIGI GALVONANY.
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HE WAS THE LEADING PROFESSOR
AT THE UNIVERSITY OF ITALY IN BOLOGNA.
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HE WOULD TAKE A METAL OBJECT, TOUCH IT TO
THE LEG OF A DEAD FROG WHICH WOULD TWITCH.
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SO HE BEGAN TO THINK THAT ELECTRICITY WAS
SOMEHOW BEHIND THE MOVEMENTS OF THE LIMBS OF
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ANY LIVING CREATURE. IN THE MOST
FAMOUS EXPERIMENT, HIS NEPHEW CAME TO
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LONDON AND COLLECTED A DEAD PRISONER FROM NEW
GATE PRISON AND BROUGHT HIM TO THE OPERATING
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THEATER AND RAN INCREASINGLY LARGE VOLTAGE,
ARCS OF ELECTRICITY THROUGH HIM, UNTIL
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THIS CORPSE OPENED AND CLOSED HIS EYES, PUT
UP HIS HAND, AND THEN WITH THE LARGEST VOLTAGE
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ACTUALLY SAT UP. THAT'S THE CUTTING
EDGE EXPERIMENT THAT MARY SHELLEY IS
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BASING HER NOVEL ON. GALVONI TAUGHT
US THAT ELECTRICITY WAS OPERATING AND
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COULD DO THINGS LIKE GENERATE A MUSCLE
TWITCH. SO WHAT HE EXPLICITLY WAS ABLE
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TO DISCOVER WAS THAT BY CHANGING ELECTRICAL
POTENTIAL ACROSS A PIECE OF MUSCLE, HE NOTICED IT
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MOVED. IN SOME SENSE WE
ARE ELECTRO MECHANICAL DEVICES.
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IT ALSO MAKES POSSIBLE THE COGNITION
OF THE BRAIN. Narrator: MARY IMAGINES
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PUSHING EXPERIMENTS INTO ANATOMY
AND ELECTRICITY A DARK STEP FURTHER.
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A FICTIONAL CHARACTER BEGINS TO TAKE SHAPE
IN HER MIND. A YOUNG SCIENTIST, DR. VICTOR
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FRANKENSTEIN. THIS WAS THE EXACT
MECHANISM OF WRITING SCIENCE FICTION.
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YOU TAKE SOMETHING THAT IS TRUE TO THE
SCIENCE OF YOUR TIME, YOU SAY, WELL, WHAT IF?
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AND SO SHE WAS DOING THE ACT OF SCIENCE FICTION,
AND BEFORE THAT WE HAD GOTHICS, WE HAD FANTASTIC
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ADVENTURES, ABOUT YOU BUT THEY WERE
NEVER BUILT OUT OF THE SCIENCE OF THE TIME.
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IN THE BOOK, VICTOR FRANKENSTEIN
SEES LIGHTNING SPLIT AND DESTROY A HUGE OAK
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TREE AND HE'S SO IMPRESSED WITH THE POWER OF
THAT THAT HE STARTS MAKING EXPERIMENTS WITH
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00:06:00,927 --> 00:06:07,099
LIGHTNING. WHEN HE GOES TO
THE UNIVERSITY, HE IMMEDIATELY SEEKS
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00:06:07,233 --> 00:06:12,904
OUT THE PROFESSOR WHO IS DOING ELECTRICAL
EXPERIMENTS AND LEARNS FROM HIM THE CONNECTIONS
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00:06:13,039 --> 00:06:20,178
BETWEEN ELECTRICITY AND LIFE. Narrator:
MEDICAL SCIENCE ACKNOWLEDGES WHAT MARY SHELLEY
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PONDERED NEARLY TWO CENTURIES
AGO. ELECTRICITY IS INDEED A KEY
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COMPONENT OF LIFE. NO ONE KNOWS THIS BETTER
THAN DR. REGGIE EDGERTON, WHO'S BREAK
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THROUGH RESEARCH AT UCLA MAY HELP CURE A
TYPE OF PARALYSIS COMMONLY BELIEVED TO BE
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PERMANENT. ELECTRICITY AND THE
BODY IS PARTICULARLY ON THE NERVOUS
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00:06:42,702 --> 00:06:50,702
SYSTEM, THE BRAIN IS GENERATING THESE
ELECTRICAL SIGNALS THAT MAKE IT CONTRACT.
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Narrator: IN SHELLY'S TIME, IT WAS
PURE FICTION. BUT TODAY, DR. EDGERTON'S
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GROUNDBREAKING STUDIES WITH LAB
ANIMALS SHOW FICTION CAN BECOME REALITY.
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WE WANT TO KNOW HOW COMMUNICATE WITH
THE SPINAL CORD, SO WE'RE TESTING IN RATS
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WHILE THEY'RE WALKING ON A TREADMILL AND
STANDING. ONE OF THE THINGS THAT WE FOUND
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00:07:19,405 --> 00:07:24,743
PARTICULARLY WITH THE HIND LIMBS IS MUCH OF THE
DETAILS OF THESE COMMANDS ARE NOT REALLY IN THE
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BRAIN BUT THEY'RE IN THE SPINAL
CORD. YOU CAN TAKE THE SPINAL CORD
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OUT, PUT IT IN A DISH AND ELECTRICALLY
STIMULATE THIS SPINAL CORD AND IT WILL GENERATE
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STEPPING-LIKE PATTERNS. Narrator: DR. EDGERTON
AND HIS TEAM PLACE ELECTRODES WITHIN
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THE RATS TO UNDERSTAND THE
SPINAL CORD'S LEARNING CAPABILITIES.
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WE IMPLANT NEW ELECTRODES IN THE RAT TO
PROJECT CURRENT TO SPECIFIC PARTS OF THE SPINAL
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CORD THAT WILL RESULT IN SPECIFIC
MOVEMENTS. THIS COMBINATION OF ELECTRODES,
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WHILE BEING TRAINED, MAY HELP TO RECOVER
FROM PARALYSIS. BUT CAN A TECHNIQUE USED TO
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MAKE PARALYZED RATS WALK BE USED ON
HUMANS? ONE MAN WHO WANTS TO KNOW IS ROB
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SUMMERS. MY JOURNEY
STARTED ABOUT 5 1/2 YEARS AGO.
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00:08:19,499 --> 00:08:23,902
I WAS A COLLEGE BASEBALL PLAYER, PLAYING BALL
FOR OREGON STATE. I WAS WELL ON MY WAY TO
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ACHIEVING MY GOALS AND DREAMS OF
BECOMING A PROFESSIONAL BASEBALL PLAYER.
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SOMETHING THAT STARTED BACK
WHEN I WAS 12. IT WAS JULY 12TH OF 2006.
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WENT OUT TO MY CAR TO GET MY WORKOUT BAG AND
WAS STRUCK BY A CAR STANDING AT THE END OF MY
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DRIVEWAY. I FLIPPED UP OFF THE HOOD,
BROKE MY NECK, LEAVING ME PARALYZED
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00:08:44,590 --> 00:08:51,696
FROM THE NECK DOWN. Narrator: AT THE
UNIVERSITY OF LOUISVILLE IN KENTUCKY, ROB
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HAS UNDERGONE OVER 80 SESSIONS OF SPINAL CORD
STIMULATION. A TECHNIQUE CO-DEVELOPED BY DR.
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EDGERTON ON RATS. WITH THE
SURGERY, THEY IMPLANTED THE EPIDURAL
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STIMULATOR IN MY LOWER BACK WITH
ELECTRODES LEADING INTO MY SPINAL CORD.
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00:09:09,482 --> 00:09:13,161
ON THE THIRD DAY OF TURNING ON THE STIMULATOR,
I GOT UP IN THE HARNESS ON THE TREADMILL AND I
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00:09:13,185 --> 00:09:17,522
STOOD THERE INDEPENDENTLY WITHOUT ANYONE'S
HANDS ON ME. THAT WAS THE FIRST TIME I'D BEEN
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00:09:17,657 --> 00:09:23,428
ABLE TO DO THAT IN FOUR YEARS. WHEN HE'S TRYING
TO STAND, WE CAN ENGAGE THE BRAIN AS WELL AS
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00:09:23,563 --> 00:09:28,333
THE SPINAL CORD AND GET BOTH OF THEM WORKING, AND
I THINK WHAT'S HAPPENING OVER A PERIOD OF TIME,
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00:09:28,467 --> 00:09:34,205
THE TWO ARE TRYING TO FIGURE OUT HOW TO GET
COORDINATED. MY DAY TO DAY ROUTINE, I WILL
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USE A HANDHELD DEVICE TO TURN THE STIMULATOR
ON, AND I'LL WORK ON STANDING INDEPENDENTLY FOR
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ANYWHERE BETWEEN AN HOUR TO AN HOUR
AND A HALF. FIRST DAYS OF TESTING, WE
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WERE A LITTLE TAKEN ABACK BY HOW QUICKLY HE WAS
ABLE TO STAND, BECAUSE WE WERE PRETTY NAIVE, NO
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ONE HAD REALLY DONE THIS EXPERIMENT
BEFORE IN AN INDIVIDUAL THAT WAS COMPLETELY
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PARALYZED. IN ONE YEAR I SEE
MYSELF BEING ABLE TO TAKE STEPS.
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00:10:03,469 --> 00:10:09,507
IN FIVE YEARS, I SEE MYSELF WALKING
WITH A CANE OR WALKING NORMALLY.
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I KNOW IT'S HARD WORK AND I'VE GOT A LONG ROAD
AHEAD OF ME BUT I'LL ALWAYS REACH FOR THOSE
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00:10:14,880 --> 00:10:19,217
GOALS AND NEVER LET A GOAL
GO UNACHIEVED. Narrator: MEDICAL
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BREAKTHROUGHS LIKE THIS HARKENED BACK TO THE
EARTH SHATTERING NEW DISCOVERIES BEING MADE DURING
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THE SCIENTIFIC REVOLUTION 200
YEARS AGO. IN THE SUMMER OF 1816, MARY
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SHELLEY WAS FASCINATED WITH THE
POWER AND POSSIBILITY OF MODERN SCIENCE.
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BUT HER FIRST CONCERN WAS CREATING A
COMPELLING STORY FOR LORD BYRON'S CHALLENGE.
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00:10:42,141 --> 00:10:46,811
MARY HAD A HARD TIME GETTING
STARTED. SHE WANTED TO LIVE UP TO HER
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MOTHER'S MEMORY AND HER FATHER'S
EXPECTATIONS. Narrator: INSPIRATION FINALLY
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00:10:51,917 --> 00:10:56,588
STRUCK ON A FATEFUL SUMMER NIGHT AS STORIES OF
ANCIENT GHOSTS AND MODERN SCIENCE STIRRED IN MARY'S
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DREAMS. โชโช I SAW
THE PAINED STUDENT
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LEANING BESIDE THE THING HE HAD PUT
TOGETHER. I SAW THIS MAN STRETCHED OUT.
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00:11:33,659 --> 00:11:41,659
AND THEN ON THE WORKING OF SOME ENGINE SHOWED
SIGNS OF LIFE. AND IN A FRENZIED NIGHTMARE,
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A NEW LEGEND HAD BEEN BORN. I HAVE
FOUND IT. WHAT TERRIFIED ME WILL TERRIFY
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00:11:51,310 --> 00:11:59,310
OTHERS. WHAT'S THE TITLE OF
ANOTHER SCIENCE FICTION NOVEL SHE WROTE?
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WAS IT "THE INVISIBLE MAN," "THE LAST MAN,"
"FRANKENSTEIN 2" OR "YOUNG FRANKENSTEIN"?
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THE ANSWER IS COMING UP.
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Narrator: MARY SHELLEY BEGINS TO STITCH
TOGETHER HER STORY, FUELED BY THE PRESENT AND
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HAUNTED BY HER PAST. THE CENTRAL
FACT OF MARY SHELLEY'S LIFE IS REALLY HER
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BIRTH. BECAUSE HER MOTHER DIED
GIVING BIRTH TO HER, SOMETHING WHICH
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SHE LIVED WITH FOR HER WHOLE LIFE.
AND SO THE WHOLE IDEA THAT BIRTH
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AND CREATION COULD BE DESTRUCTIVE, I
THINK, WAS PROBABLY PART OF HER DNA ALMOST.
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Narrator: AS A CHILD, MARY WOULD TAKE REFUGE
IN THE CEMETERY, ATTEMPTING TO COMMUNE
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WITH THE SPIRIT OF HER LATE
MOTHER. CERTAINLY WHEN SHE WAS
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YOUNGER SHE WOULD GO THERE AND SHE
WOULD TELL HER HER WISHES AND DREAMS.
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THAT WAS A VERY, VERY IMPORTANT ELEMENT
OF HER LIFE. OBSESSED WITH HER MOTHER.
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00:13:18,931 --> 00:13:22,801
SHE READ ALL HER MOTHER'S WRITINGS.
SHE WOULD TAKE THEM TO READ ON
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00:13:22,935 --> 00:13:27,172
HER MOTHER'S GRAVE. HER LIFE SEEMED TO BE
ORIENTED TOWARD AN ATTEMPT TO OVERCOME
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00:13:27,306 --> 00:13:32,644
THE LOSS OF HER MOTHER WHICH THE GRAVE
REPRESENTED. Narrator: MARY SHELLEY POURED
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00:13:32,778 --> 00:13:37,649
MANY OF HER OWN EXPERIENCES INTO THE LIFE
OF VICTOR FRANKENSTEIN. IN THE NOVEL, VICTOR
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00:13:37,783 --> 00:13:42,587
FRANKENSTEIN IS OBSESSED WITH
DEATH. WHEN HIS MOTHER DIES, JUST AS
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HE'S GOING OFF TO COLLEGE, HE WAS VERY CLOSE
TO HER, HE'S ABSOLUTELY DISTRAUGHT, AND
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DECIDES AT THAT POINT TO DEDICATE HIS
LIFE TO TRYING TO BRING BACK THE DEAD.
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00:13:51,964 --> 00:13:58,603
VICTOR FRANKENSTEIN GETS HIS PIECES TO MAKE HIS
CREATURE FROM CEMETERIES AND SLAUGHTERHOUSES
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00:13:58,737 --> 00:14:04,676
AND THE TURN TO CEMETERIES COULD ECHO MARY
SHELLEY'S FREQUENT VISITS TO HER MOTHER'S TOMB.
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00:14:04,810 --> 00:14:08,646
Narrator: MARY SHELLEY KNOWS STUDYING THE DEAD
IS CRUCIAL IF ONE WISHES TO UNLOCK THE SECRETS
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00:14:08,781 --> 00:14:16,781
OF LIFE. IN MARY SHELLEY'S DAY,
DOCTORS WHO WANTED TO STUDY
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00:14:17,790 --> 00:14:21,459
ANATOMY HAD TO GET CORPSES TO DO
SO. AND THEY WOULD HIRE MEN TO GO TO
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00:14:21,594 --> 00:14:25,096
CEMETERIES AND DIG UP RECENTLY-BURIED
CORPSES. THEY PREFERRED THEM AS FRESH AS
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00:14:25,231 --> 00:14:31,402
POSSIBLE. AND I THINK SHE'S PLAYING
OFF THAT IDEA, TOO, THAT MAYBE
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00:14:31,537 --> 00:14:37,542
VICTOR FRANKENSTEIN ISN'T WRONG TO GO AND GET
DEAD PIECES AND TRY TO MAKE THEM LIVE AGAIN.
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00:14:37,676 --> 00:14:43,548
Narrator: LOS ANGELES CHIEF CORNER CRAIG HARVEY
HAS INTIMATE KNOWLEDGE OF THE FRONTIER THAT
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00:14:43,682 --> 00:14:49,287
SEPARATES LIFE AND DEATH. DEATH IS
WHEELED INTO HIS OFFICE ON A REGULAR BASIS.
141
00:14:49,421 --> 00:14:54,759
WHEN A BODY FIRST COMES INTO THE CORONER'S
OFFICE, IT COMES IN THROUGH WHAT WE CALL OUR
142
00:14:54,894 --> 00:15:01,432
LOADING DOCK. THE BODIES ARE WEIGHED
AND MEASURED AND THEN MOVED INTO THE
143
00:15:01,567 --> 00:15:09,567
PROCESSING ROOM FROM THERE. AN OVERHEAD
PHOTOGRAPH IS TAKEN OF THE BODY THAT DOCUMENTS THE
144
00:15:10,409 --> 00:15:16,581
CONDITION OF THE BODY WHEN IT ARRIVED IN
OUR FACILITY. THE BODY CAN BE FINGERPRINTED
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00:15:16,715 --> 00:15:23,988
AND THE BODY WILL THEN BE PLACED BACK INTO OUR
COLD CRYPT FOR STORAGE, PENDING EXAMINATION.
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00:15:24,123 --> 00:15:29,894
Narrator: DEATH MAY COME IN MANY
FORMS, BUT DEATH ITSELF HAS ONLY TWO FACES.
147
00:15:30,029 --> 00:15:38,029
THE TWO FACES OF DEATH ARE SOMATIC DEATH, THE
CESSATION OF RESPIRATION, OF CIRCULATION, OF
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THE BLOOD, OF BRAIN ACTIVITY, AND THEN THE
MOLECULAR DEATH IS SIMPLY THE DECOMPOSITION OF THE
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00:15:50,182 --> 00:15:56,321
HUMAN BODY. THERE MAY BE SOME
SPONTANEOUS MOVEMENT IN THE BODY BASED ON
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00:15:56,455 --> 00:16:04,455
THE LAST SIGNALS SENT FROM THE BRAIN, BUT IT
WILL SLOWLY DIE OUT AS THE SIGNAL TERMINATES.
151
00:16:05,464 --> 00:16:10,335
CHIEF HARVEY DISPLAYS THIS IDEA OF
RESIDUAL ELECTRICAL SIGNALS WITH A SIMPLE
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00:16:10,469 --> 00:16:15,239
DEMONSTRATION. THE WATER BALLOON
FILLED WITH WATER REPRESENTS THE HUMAN
153
00:16:15,374 --> 00:16:20,178
BRAIN. THE L.E.D. SHOT GLASSES
REPRESENT A LIMB OF THE BODY,
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00:16:20,312 --> 00:16:23,581
RIGHT ARM, LEFT ARM, LEFT LEG, RIGHT
LEG. IF I TAKE THIS NEEDLE AND BRICK
155
00:16:23,716 --> 00:16:30,989
THE BALLOON, WE SEE THAT WE'RE
GETTING FLASHES INSIDE THE SHOT GLASSES.
156
00:16:31,123 --> 00:16:35,393
THIS REPRESENTS THE BRAIN SENDING
SIGNALS TO THE RESPECTIVE LIMB, TO WALK, TO
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00:16:35,527 --> 00:16:43,527
LIFT OUR LEG, TO MOVE OUR ARMS AND SO
FORTH. AND IF YOU POP THE BALLOON, THE
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00:16:45,237 --> 00:16:48,973
BALLOON, REPRESENTING THE BRAIN, NO LONGER
IS FUNCTIONING. IT'S NO LONGER SENDING ANY
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SIGNALS TO THE VARIOUS LIMBS, AND IF THE BODY
CONTINUES MOVING ON, ONCE THE HEART AND BRAIN
160
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HAVE CEASED FUNCTION, IS THE BODY
REALLY DEAD. LIFE AND DEATH COULD BE MORE
161
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GRAY AREA THAN YOU THINK. Narrator: IT IS
THIS GRAY AREA THAT ALLOWS DOCTORS TO TAKE
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PARTS OF THE DEAD AND TURN THEM BACK INTO
THE LIVING THROUGH MEDICAL TRANSPLANTS.
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IT IS POSSIBLE TO HARVEST PARTS OF THE BODY
AFTER DEATH. THERE'S THE HARVESTING THAT'S
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DONE FOR LIVE ORGANS, AND THAT'S AFTER TWO
PRONOUNCEMENTS OF BRAIN DEATH BY PHYSICIANS.
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THE OTHER PART IS THE HARVESTING
OF TISSUES. TISSUES SUCH AS SKIN, LUNG,
166
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BONES, HEART VALVES, CORNEAS OF THE EYES, THOSE
THINGS CAN BE HARVESTED UP TO ABOUT 12 HOURS
167
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AFTER DEATH. Narrator: STITCHING
TOGETHER BODY PARTS WAS CONSIDERED
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IMPOSSIBLY GHOULISH WHEN MARY SHELLEY
WROTE ABOUT IT EARLY IN THE 19th CENTURY.
169
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TODAY TISSUE AND ORGAN TRANSPLANTS
ARE CONSIDERED COMMON PLACE.
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THE FIRSTHAND TRANSPLANT SURGERY CONDUCTED IN
THE UNITED STATES WAS PERFORMED IN 1999, ONLY 12
171
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YEARS AGO. LIMB TRANSPLANTS
REPRESENT A GREATER CHALLENGE, REPLACING A
172
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HAND AND HAVING THAT HAND CONTRACT, EXPAND,
GRASP, TO RECONNECT ALL OF THAT SENSING
173
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NERVES, TISSUE, AND DO THE THINGS THAT AN
OTHERWISE NORMAL HEALTHY HAND DOES DO HAS GOT TO
174
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BE COMPLEX SO THAT THE HAND FUNCTIONS LIKE
YOU WANT IT TO. Narrator: MARY SHELLEY
175
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DESCRIBES VICTOR FRANKENSTEIN STITCHING
TOGETHER PIECES OF DEAD BODIES 200 YEARS AGO.
176
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MARY SHELLEY DIDN'T ACTUALLY KNOW HOW
SCIENTIFIC EXPERIMENTS WERE PERFORMED, BUT SHE
177
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UNDERSTOOD WHAT VICTOR WAS TRYING
TO DO. AND SHE UNDERSTOOD THAT IN TERMS
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OF CUTTING EDGE RESEARCH IT WAS THEORETICALLY
POSSIBLE TO DO. Narrator: AS MARY DESCRIBES A
179
00:18:48,160 --> 00:18:51,440
CUTTING EDGE EXPERIMENT THAT CREATES LIFE,
SHE ARRIVES AT A TERRIFYING POSSIBILITY.
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IF MAN CREATES LIFE, WHAT'S TO STOP HIM FROM
UNLEASHING SOMETHING FAR MORE POWERFUL THAN
181
00:18:57,369 --> 00:19:02,173
HIMSELF?
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Narrator: LONDON, 1812. FOUR YEARS BEFORE
THAT FATEFUL SUMMER IN GENEVA, SWITZERLAND.
183
00:19:19,191 --> 00:19:22,871
MARY SHELLEY'S ENDLESS ATTEMPTS TO CONNECT WITH
THE MOTHER SHE NEVER KNEW SHAPES BOTH HER LIFE
184
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AND HER WORK. WHEN SHE WAS 5, HER
FATHER, WILLIAM GODWIN MARRIED AGAIN TO
185
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HAVE A MOTHER FOR HIS CHILDREN. AT THE AGE OF
16, SHE EE LOPES WITH PERCY SHELLEY WHO'S MARRIED
186
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AT THE TIME. MARY GOT PREGNANT WHEN
SHE WAS 16, GAVE BIRTH WHEN SHE WAS 17
187
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TO A LITTLE GIRL WHO LIVED FOR ONLY
TWO WEEKS. SHE WAS BORN PREMATURELY.
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Narrator: MARY WAS DEVASTATED BY THE LOSS
OF HER CHILD. MARY SHELLEY HAD A RECURRENT
189
00:20:00,699 --> 00:20:07,238
DREAM AFTER HER BABY DIED WHICH SHE RECORDED
IN HER JOURNAL. MY LITTLE BABY HAD COME TO
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00:20:07,372 --> 00:20:11,976
LIFE AGAIN. IT HAD ONLY BEEN COLD.
I RUBBED IT BEFORE THE FIRE AND
191
00:20:12,110 --> 00:20:17,582
IT LIVED. THEN I AWAKE TO FIND NO
BABY. AND THAT EXPERIENCE OF GIVING
192
00:20:17,716 --> 00:20:23,754
REBIRTH TO A DEAD CHILD THROUGH FIRE IS CRITICAL
TO WHAT VICTOR FRANKENSTEIN DOES IN THE NOVEL
193
00:20:23,889 --> 00:20:30,661
WHERE HE BRINGS THE CREATURE
ALIVE WITH A, QUOTE, SPARK OF LIFE.
194
00:20:30,796 --> 00:20:35,733
Narrator: A YEAR AFTER THE DEATH OF HER CHILD,
MARY CREATES A FICTIONAL CHARACTER WHO CAN DO
195
00:20:35,867 --> 00:20:43,867
WHAT SHE CAN'T. BREATHE LIFE INTO
DEAD FLESH. IT'S THE IDEA THAT WE COULD,
196
00:20:44,343 --> 00:20:47,311
A, COME BACK FROM THE DEAD, AND, B,
HAVE MORE CONTROL OVER OUR OWN FATES.
197
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IF ONLY WE WERE MORE POWERFUL THAN
WE ARE. IF ONLY WE DIDN'T HAVE TO DIE.
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00:20:55,420 --> 00:21:03,394
Narrator: ON A COLD WINTER NIGHT, AFTER
COUNTLESS HOURS OF EFFORT, VICTOR FRANKENSTEIN
199
00:21:03,528 --> 00:21:11,528
ACHIEVES A BREAKTHROUGH WHEN HE SEES
THE DULL, YELLOW EYES OF HIS CREATURE OPEN.
200
00:21:12,437 --> 00:21:20,437
HERS IS THE FIRST STORY IN WHICH A HUMAN
BEING CREATES ANOTHER HUMAN BEING WITHOUT A
201
00:21:21,847 --> 00:21:28,052
WOMAN AND WITHOUT ANY DIVINE INTERVENTION.
Narrator: SHELLEY'S VISION OF
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00:21:28,186 --> 00:21:31,332
A REALM OF WHERE SUCH THINGS ARE POSSIBLE
BECOMES A NEW GENRE. I THINK SCIENCE FICTION
203
00:21:31,356 --> 00:21:38,629
WRITERS THEMSELVES PLAY GOD BECAUSE THEY
CREATE WORLDS. THE ROLE OF THE CREATOR OF AN
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00:21:38,764 --> 00:21:45,202
ENTIRE UNIVERSE IS SOMETHING THAT
SCIENCE FICTION WRITERS TAKE TO THEMSELVES.
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00:21:45,337 --> 00:21:49,273
SO IT'S AN ENTIRELY APPROPRIATE THEME FOR
THEM TO EXPLORE. Narrator: IN THE WORLD OF
206
00:21:49,408 --> 00:21:55,913
SHELLEY'S NOVEL, VICTOR FRANKENSTEIN FIRST
PONDERS WHAT SIZE HIS CREATURE SHOULD BE.
207
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VICTOR FRANKENSTEIN DECIDES TO MAKE HIS CREATURE
BIGGER THAN LIFE SIZE BECAUSE, AS HE SAYS,
208
00:22:01,219 --> 00:22:05,256
BIGGER PIECES ARE EASIER TO WORK
ON. AND SO HE CREATES AN EIGHT-FOOT
209
00:22:05,390 --> 00:22:11,228
MONSTER BY USING BOTH HUMAN BONES
FROM CEMETERIES BUT ALSO ANIMAL BONES FROM
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00:22:11,363 --> 00:22:15,700
SLAUGHTERHOUSES. THAT'S THE WAY HE CAN
FINALLY PRODUCE A CREATURE WHO'S SO MUCH
211
00:22:15,834 --> 00:22:23,834
BIGGER THAN THE ORDINARY HUMAN. Narrator: IN
HIS QUEST TO CREATE LIFE, VICTOR WORKED WITH
212
00:22:30,315 --> 00:22:32,760
LARGE BODY PARTS THAT WERE FULLY
GROWN. BUT RECENT BREAKTHROUGHS MADE BY
213
00:22:32,784 --> 00:22:38,923
THE HUMAN GENOME PROJECT PROMISE TO REVEAL
THE WAY LIFE IS MADE AT THE MOLECULAR LEVEL.
214
00:22:39,057 --> 00:22:47,057
IT'S A MULTI YEAR, MULTI NATION ENDEAVOR
THAT WAS PUT TOGETHER TO TRY AND BASICALLY
215
00:22:48,166 --> 00:22:52,536
DETERMINE THE ENTIRE SEQUENCE OF DNA BASES THAT
COMPRISE ALL THE GENETIC INFORMATION IN HUMANS.
216
00:22:52,671 --> 00:22:57,975
INVOLVED TAKING ROUGHLY 3.2 BILLION PIECES
OF INFORMATION, WHICH IS THE LENGTH OF A DNA
217
00:22:58,110 --> 00:23:00,911
SEQUENCE, AND DETERMINING
EXACTLY WHAT EACH BASE OF THAT WAS.
218
00:23:01,046 --> 00:23:06,450
WHAT EVERY COMPONENT OF OUR DNA
WAS. WE DON'T KNOW WHAT MOST OF
219
00:23:06,585 --> 00:23:11,222
THE GENES DO. WE KNOW WHAT THEY LOOK
LIKE, WE KNOW HOW TO REARRANGE THEM, BUT
220
00:23:11,356 --> 00:23:14,725
WE DON'T KNOW THE FUNCTION OF MANY OF
THESE GENES. Narrator: EXPERTS BELIEVE
221
00:23:14,860 --> 00:23:19,397
ONGOING ANALYSIS OF THE FINDINGS COULD SHAKE
UP MANY ESTABLISHED SCIENTIFIC THEORIES.
222
00:23:19,531 --> 00:23:27,037
IT WILL CHANGE HOW WE UNDERSTAND HOW
LIFE WORKS. IT WILL CHANGE THE DETAILS OF
223
00:23:27,172 --> 00:23:33,411
UNDERSTANDING PROCESSES. IT WILL REVEAL WE
PROBABLY DON'T UNDERSTAND SOME OF THE DETAILS
224
00:23:33,545 --> 00:23:36,847
WE THOUGHT WE KNEW BEFORE AND THAT
SOME OF THE DETAILS MAY BE MORE COMPLEX.
225
00:23:36,982 --> 00:23:41,318
Narrator: NOW THAT SCIENTISTS NOW HOW LIFE
IS CREATED NATURALLY, COULD THEY USE THIS
226
00:23:41,453 --> 00:23:45,456
SAME INFORMATION TO MANUFACTURE LIFE
SYNTHETICALLY? ACCORDING TO SOME, WE NOW HAVE.
227
00:23:45,590 --> 00:23:53,590
IN MAY 2010, GENETIC CARTOGRAPHER, SYNTHETIC
LIFE, MANUFACTURED BY MAN, BROUGHT TO
228
00:23:53,799 --> 00:24:01,799
LIFE IN A LABORATORY. THEY'VE ACTUALLY
SYNTHESIZED THE MOLECULE, INCORPORATED THIS
229
00:24:10,982 --> 00:24:18,055
DNA MOLECULE INTO A CELL LACKING DNA AND SHOWED
THAT ESSENTIALLY THIS NEW SYNTHETIC DNA MOLECULE
230
00:24:18,190 --> 00:24:22,126
COULD TAKE OVER THE CELL AND
ESSENTIALLY DIRECT ITS FUTURE LIFE.
231
00:24:22,260 --> 00:24:30,260
Narrator: THE ABILITY TO CREATE
SYNTHETIC LIFE FORMS OPENS UP COUNTLESS
232
00:24:37,909 --> 00:24:40,621
POSSIBILITIES. IF WE THINK WE UNDERSTAND
HOW AN ORGANISM WORKS, WE CAN CREATE
233
00:24:40,645 --> 00:24:43,624
ORGANISMS WHICH HAVE KNOWN GENETIC COMPOSITIONS
AND THEN CARRY OUT OTHER FUNCTION, SUCH
234
00:24:43,648 --> 00:24:48,519
AS HYDROCARBONS FOR ENERGY, OR PROTEINS
FOR CREATING A VACCINE FOR DISEASE.
235
00:24:48,653 --> 00:24:50,665
Narrator: BUT DOES THE ORGANISM
TRULY QUALIFY AS A LIVING CREATURE?
236
00:24:50,689 --> 00:24:56,360
THE ANSWER WOULD DEPEND ON THE DEFINITION
OF LIFE ITSELF. THERE ARE CHARACTERISTICS OF
237
00:24:56,495 --> 00:25:02,333
LIFE WE CAN IDENTIFY. LIFE HAS TO REPRODUCE
ITSELF. IT HAS TO ABSORB ENERGY FROM THE
238
00:25:02,467 --> 00:25:09,240
ENVIRONMENT. IT HAS TO EXCRETE
WASTE. BUT THERE'S ALSO THESE GRAY
239
00:25:09,374 --> 00:25:14,478
AREAS LIKE VIRUSES. THEY ALSO SELF-REPLICATE,
THEY ALSO CONSUME ENERGY TO A DEGREE,
240
00:25:14,613 --> 00:25:19,083
BUT THEY ARE PARASITES. THERE'S
NO UNIVERSALLY-ACKNOWLEDGED
241
00:25:19,217 --> 00:25:22,453
DEFINITION OF LIFE IN THE AGE OF
BIOTECHNOLOGY. Narrator: VICTOR FRANKENSTEIN
242
00:25:22,587 --> 00:25:25,956
DIDN'T JUST CREATE LIFE, HE CREATED
INTELLIGENT LIFE. THE CREATURE IS EXTREMELY
243
00:25:26,091 --> 00:25:32,329
INTELLIGENT. HE UNDERSTANDS HOW NATURE
WORKS, HE IS ACUTELY AWARE THAT HE DOES
244
00:25:32,464 --> 00:25:39,336
NOT LOOK THE WAY OTHERS LOOK. Narrator:
MARY SHELLEY'S VISION OF MAN CREATING
245
00:25:39,471 --> 00:25:44,074
INTELLIGENCE APPEARS PROPHETIC. NOW, NEARLY
200 YEARS LATER, SUPER COMPUTERS ARE QUICKLY
246
00:25:44,209 --> 00:25:50,981
APPROACHING PARODY WITH THE HUMAN
BRAIN. BUT HOW WILL THE WORLD CHANGE
247
00:25:51,116 --> 00:25:54,885
WHEN COMPUTERS BECOME SMARTER
THAN HUMANS?
248
00:26:04,796 --> 00:26:12,102
FRANKENSTEIN'S THESIS STARTED OFF AS WELL
MEANING, THINKING ACTUALLY IT WOULD HELP
249
00:26:12,237 --> 00:26:16,507
MEDICALLY AS TO CREATE LIFE. IT MEANT
HE'D HAVE TO TAKE A BODY AND ACTUALLY START
250
00:26:16,641 --> 00:26:22,279
EXPERIMENTING ON A DEAD BODY AND
TRYING TO IGNITE LIFE INTO THE DEAD BODY.
251
00:26:22,414 --> 00:26:30,414
IF I WAS A SCIENTIST ON THAT ROLE,
THERE'S NO WAY I COULD BE STOPPED.
252
00:26:30,889 --> 00:26:37,494
I WOULD DEFINITELY CONTINUE TO DO
THAT. BUT IT MAY LEAD YOU INTO TROUBLE
253
00:26:37,629 --> 00:26:40,174
THAT YOU CAN'T CONTROL. AND THEREFORE
THE WHOLE PROCESS OF HIS INTENTION BECAME
254
00:26:40,198 --> 00:26:44,668
PERVERTED. THEREFORE, WE SEE
MADNESS. AND OUT OF THAT HE CREATES WHAT
255
00:26:44,803 --> 00:26:52,743
YOU SEE IS A MONSTER. MARY SHELLEY CREATED
A HALF LIVING, HALF DEAD CREATURE WHO
256
00:26:52,877 --> 00:26:56,614
WAS ANOTHER VERSION OF HUMANITY AND
WE'VE BEEN GRIPPED BY THAT IDEA EVER SINCE.
257
00:26:56,748 --> 00:27:02,086
PEOPLE ARE STILL SPECULATING AS TO WHY
SUDDENLY VICTOR FRANKENSTEIN IS SO ALIENATED
258
00:27:02,220 --> 00:27:08,659
FROM THIS CREATURE HE'S BEEN TRYING TO
BRING TO LIFE. BUT ONCE THE CREATURE COMES
259
00:27:08,793 --> 00:27:11,706
ALIVE, HE'S TERRIFIED. SUDDENLY HE'S
PRESENTED WITH THE RESPONSIBILITY OF A NEW
260
00:27:11,730 --> 00:27:19,730
CREATION. HE WANTS NOTHING
TO DO WITH IT. HE JUST RUNS AWAY.
261
00:27:22,140 --> 00:27:29,179
THE CREATURE HAS TO SET OUT INTO THE WORLD
ALL BY HIMSELF. Narrator: THE CREATURE ENTERS
262
00:27:29,314 --> 00:27:35,219
THE WORLD AS A BLANK SLATE BUT IN MERE
MONTHS DEVELOPS A FULLY REALIZED INTELLECT.
263
00:27:35,353 --> 00:27:39,490
HE LEARNS HOW TO SPEAK AND READ
AND WRITE THROUGH WATCHING A FAMILY.
264
00:27:39,624 --> 00:27:44,328
AND IN A WAY IT'S KIND OF THE WAY MARY LEARNED
THINGS TO SOME DEGREE HAPHAZARDLY AND SHE
265
00:27:44,462 --> 00:27:48,499
LEARNED ALSO FROM LISTENING TO PEOPLE
ALL THE TIME FROM THE TIME SHE WAS YOUNGER.
266
00:27:48,633 --> 00:27:54,304
Narrator: SPYING ON THE FAMILY FOR DAYS
ON END, THE CREATURE QUICKLY MASTERS SPEECH
267
00:27:54,439 --> 00:27:56,751
AND LANGUAGE. WITH THE MONSTER'S
ADVANCED LEARNING CAPABILITIES, MARY
268
00:27:56,775 --> 00:28:00,644
SHELLEY SHELLEY THOUGHT MAN COULD
CREATE INTELLIGENCE GREATER THAN HIS OWN.
269
00:28:00,779 --> 00:28:04,815
GIVEN THE POWER OF 21st CENTURY TECHNOLOGY,
HAS MARY SHELLEY'S PROPHECY COME TRUE?
270
00:28:04,949 --> 00:28:12,949
DR. CHARLES PECK MAY HAVE THE
ANSWER. MY JOB IS TO TRY TO
271
00:28:13,825 --> 00:28:19,196
UNDERSTAND HOW THE BRAIN WORKS. AND TO USE THIS
UNDERSTANDING TO ADVANCE SCIENCE MEDICINE AND
272
00:28:19,330 --> 00:28:25,436
TECHNOLOGY. Narrator: DR. PECK
AND HIS TEAM ARE HARNESSING
273
00:28:25,570 --> 00:28:31,108
SUPERCOMPUTERS, TO LEARN MORE ABOUT
THE COMPLEX FUNCTIONS OF THE HUMAN BRAIN.
274
00:28:31,242 --> 00:28:37,414
WE'RE TRYING TO DEVELOP AN UNDERSTANDING OF
THE BRAIN BY ANALYZING NEUROSCIENTIFIC DATA.
275
00:28:37,549 --> 00:28:41,452
Narrator: EVEN IN THE 21st CENTURY, ANALYZING
A COMPLEX ORGAN SUCH AS THE BRAIN IS LIKE
276
00:28:41,586 --> 00:28:45,556
TRYING TO HIT A MOVING TARGET. IT'S VERY
DIFFICULT TO STUDY THE BRAIN, BECAUSE IT KEEPS
277
00:28:45,690 --> 00:28:53,690
CHANGING. IT'S HARD TO UNDERSTAND
THE RULES OF SOMETHING WHEN THE VERY
278
00:28:57,335 --> 00:29:02,439
NATURE OF THE RULES MIGHT BE EVOLVING IN
RESPONSE TO YOUR MANIPULATIONS TO TRY AND
279
00:29:02,574 --> 00:29:05,486
UNDERSTAND THOSE RULES. Narrator: THE
ULTIMATE GOAL OF THE PROJECT IS TO CREATE THE
280
00:29:05,510 --> 00:29:11,849
WORLD'S FIRST FULLY FUNCTIONAL
ARTIFICIAL BRAIN AND BRING IT TO LIFE.
281
00:29:11,983 --> 00:29:15,953
THEY BEGIN WITH SOMETHING A LITTLE
SIMPLER THAN A HUMAN BRAIN, A RAT'S BRAIN.
282
00:29:16,087 --> 00:29:19,857
THEIR FIRST TARGET IS A SINGLE MICROSCOPIC
NEOCOURTICAL COLUMN. THESE COLUMNS FORM THE NEURAL
283
00:29:19,991 --> 00:29:23,827
CIRCUITS WHICH FORM THE BRAIN'S
CORTEX. GAINING CONCRETE KNOWLEDGE OF
284
00:29:23,962 --> 00:29:27,965
THE RAT'S NEOCORTEX COULD POTENTIALLY UNLOCK
SECRETS ABOUT HOW THIS PART OF THE BRAIN WORKS
285
00:29:28,099 --> 00:29:32,069
IN HUMANS. NEOCORTEX IS INVOLVED
IN MOST OF THE FUNCTIONS THAT MAKE US
286
00:29:32,203 --> 00:29:40,203
HUMAN. IT'S INVOLVED IN MEMORY,
IN CONSCIOUSNESS, IN PLANNING, IN
287
00:29:41,012 --> 00:29:49,012
PERCEPTION, IN BEHAVIOR GENERATION.
SO WE REALLY WANT TO UNDERSTAND
288
00:29:49,187 --> 00:29:56,093
HOW THE NEOCORTEX WORKS. Narrator:
TO BRING HIS ARTIFICIAL BRAIN TO LIFE, DR.
289
00:29:56,227 --> 00:29:58,906
PECK RELIES ON AN IBM SUPERCOMPUTER CALLED
BLUE GENE TO DOWNLOAD THE NEUROLOGICAL
290
00:29:58,930 --> 00:30:06,930
DATA, BLUE GENE MUST BE PHYSICALLY
CONNECTED TO RAT BRAIN TISSUE.
291
00:30:07,071 --> 00:30:11,475
THIS DATA IS ACQUIRED THROUGH AN APPARATUS THAT
CONSISTS OF AN ARRANGEMENT OF 12 PATCH CLAMP
292
00:30:11,609 --> 00:30:17,548
ELECTRODES THAT PENETRATE INTO A SLICE OF RAT
TISSUE TO IDENTIFY AND MEASURE SPECIFIC NEURONS.
293
00:30:17,682 --> 00:30:25,682
Narrator: ONCE THE DATA HAS BEEN ACQUIRED, THE
NEURON'S GENE POSITION IS ALSO FED INTO BLUE
294
00:30:28,526 --> 00:30:36,526
GENE AND ANALYZED. BLUE GENE'S ANALYSIS
OF THOUSANDS OF NEOCORTICAL COLUMNS
295
00:30:37,135 --> 00:30:42,639
AND HOW THEY WORK TOGETHER WITHIN THE RAT'S
BRAIN WILL PROVIDE PECK AND HIS TEAM WITH A
296
00:30:42,774 --> 00:30:46,253
PLATFORM TO BEGIN CONSTRUCTING THEIR ARTIFICIAL
HUMAN BRAIN. IF YOU CAN FULLY CONSTRAIN
297
00:30:46,277 --> 00:30:50,180
THESE MODELS AND LINE UP ALL THE PARAMETERS
AND ALL THE CIRCUITRY AND SUCH, IT REALLY DOES
298
00:30:50,315 --> 00:30:55,352
REPLICATE WHAT'S HAPPENING IN A
REAL BRAIN. Narrator: GAINING INSIGHT
299
00:30:55,486 --> 00:30:58,446
INTO THE BRAIN'S INNER WORKINGS COULD
PROVIDE A DEEPER UNDERSTANDING OF THE
300
00:30:58,523 --> 00:31:06,063
COMPLEXITIES SURROUNDING THOUGHTS
AND CONSCIOUSNESS. IT COULD GUIDE
301
00:31:06,197 --> 00:31:12,236
NEUROSCIENTIFIC RESEARCH ON
COGNITIVE DISEASES AND MENTAL ILLNESSES.
302
00:31:12,370 --> 00:31:17,541
Narrator: WITH VIRTUAL MODELS OF HUMAN
THOUGHTS AND CONSCIOUSNESS GETTING CLOSER TO
303
00:31:17,675 --> 00:31:24,214
REALITY, COULD THE WORLD SEE ARTIFICIAL
INTELLIGENCE WITH THE SELF-AWARENESS OF A HUMAN?
304
00:31:24,349 --> 00:31:30,287
WOULD IT BE POSSIBLE TO ENCAPSULATE A PROCESS
THAT GIVES RISE TO ALL THESE FUNCTIONS
305
00:31:30,421 --> 00:31:36,059
INSIDE A COMPUTER? PROBABLY.
Narrator: MARY SHELLEY'S
306
00:31:36,194 --> 00:31:39,807
CREATURE IS A HIGHLY INTELLIGENT SELF-AWARE
BEING, BUT THAT SELF-AWARENESS IS A DOUBLE EDGED
307
00:31:39,831 --> 00:31:45,669
SWORD. THE CREATURE STARTS
OUT TRYING TO BEFRIEND EVERY HUMAN
308
00:31:45,803 --> 00:31:50,107
HE ENCOUNTERS. BUT THEY ALL RUN
AWAY IN TERROR. HE'S DRIVEN INTO THIS ALIEN
309
00:31:50,241 --> 00:31:55,512
CONDITION. THE CREATURE
BECOMES INCREASINGLY MONSTROUS.
310
00:31:55,647 --> 00:32:00,517
BUT THE ARGUMENT OF THE NOVEL IS THAT THE
PEOPLE WHO DRIVE HIM THERE ARE THE ONES WHO ARE
311
00:32:00,652 --> 00:32:05,589
RESPONSIBLE FOR MAKING HIM INTO A
MONSTER. AND IN THAT SENSE THEY'RE THE
312
00:32:05,723 --> 00:32:11,895
TRUE MONSTERS. Narrator: MARY
SHELLEY HERSELF WAS INTIMATELY
313
00:32:12,030 --> 00:32:16,733
ACQUAINTED WITH FEELING LIKE AN OUTSIDER AND
SHE POURED HER ANGUISH INTO HER CHARACTERS.
314
00:32:16,868 --> 00:32:21,271
SHE FEELS REJECTED, THE CREATURE FEELS
REJECTED, SHE FEELS LIKE SHE SHOULD HAVE BEEN
315
00:32:21,406 --> 00:32:24,875
BETTER RAISED AND NURTURED, THAT'S
THE CREATURE'S MAIN OBJECTION WITH VICTOR.
316
00:32:25,009 --> 00:32:29,379
SO SHE'S REALLY WRITING ABOUT
HERSELF. Narrator: IN MARY SHELLEY'S
317
00:32:29,514 --> 00:32:32,994
PROPHETIC VISION, TECHNOLOGY GIVES FRANKENSTEIN
THE POWER TO DESIGN HIS CREATURE'S EVERY
318
00:32:33,051 --> 00:32:35,953
DETAIL. NOW, NEARLY 200 YEARS
LATER, BREAKTHROUGHS IN GENETIC
319
00:32:36,087 --> 00:32:39,489
ENGINEERING ARE PUSHING PARENTS ONE STEP
CLOSER TO DESIGNING THEIR OWN CHILDREN.
320
00:32:39,624 --> 00:32:47,624
AND FOREVER CHANGING THE HUMAN
RACE. ALBION HOUSE, NORTHWEST OF
321
00:32:57,175 --> 00:33:04,348
LUNDEN, SPRING 1817. MARY SHELLEY'S
FIRST NOVEL IS NEARLY COMPLETE.
322
00:33:04,482 --> 00:33:09,920
IT WILL BE PUBLISHED WITH THE TITLE
"FRANKENSTEIN OR THE MODERN PROMETHEUS."
323
00:33:10,054 --> 00:33:15,325
MARY SHELLY IS CLEARLY DRAWING
ON THE MYTHS OF PROMETHEUS.
324
00:33:15,460 --> 00:33:20,097
HE GAVE THE GIFT OF FIRE TO HUMANS.
THAT HELPED TO SEPARATE US FROM
325
00:33:20,231 --> 00:33:25,635
THE ANIMALS. BUT IT ALSO MADE POSSIBLE
TREMENDOUS MISCHIEF AND DAMAGE
326
00:33:25,770 --> 00:33:30,407
WHEN WE USE FIRE TO BURN DOWN ENTIRE
FORESTS. Narrator: MARY WAS FASCINATED
327
00:33:30,541 --> 00:33:36,380
BY PROMETHEUS, WHOSE ACTIONS HAD
THE POTENTIAL TO ADVANCE THE HUMAN RACE.
328
00:33:36,514 --> 00:33:41,885
BUT TODAY, GENETIC SCIENTISTS ARE NOT JUST
ADVANCING THE HUMAN RACE, THEY'RE PERFECTING IT.
329
00:33:42,020 --> 00:33:47,657
THE MAPPING OF THE HUMAN GENOME FOR THE
MEDICAL COMMUNITY WAS AN ABSOLUTE BREAKTHROUGH.
330
00:33:47,792 --> 00:33:53,463
THE GENETIC CODE HAS PROVIDED US A DETAILED MAP
THAT ALLOWS US TO UNDERSTAND WITH INCREASING
331
00:33:53,598 --> 00:33:59,403
CLARITY EXACTLY WHAT IT IS THAT MAKES US WHO
WE ARE AND MORE AND MORE HOW TO MANIPULATE THAT
332
00:33:59,537 --> 00:34:05,842
CODE. Narrator: FERTILITY EXPERT
DR. JEFFREY STEINBERG UTILIZES A
333
00:34:05,977 --> 00:34:11,615
TEST CALLED PGD TO ENSURE
EXPECTING PARENTS HAVE HEALTHY BABIES.
334
00:34:11,749 --> 00:34:17,187
IT'S PREIMPLANTATION GENETIC
DIAGNOSIS. WHAT IT IS IS THE GENETIC STUDY
335
00:34:17,321 --> 00:34:23,693
OF HUMAN EMBRYOS CREATED WITH IN VITRO FERTILIZATION,
WHAT ALLOWS US TO MAKE GENETIC PREDICTIONS
336
00:34:23,828 --> 00:34:29,566
AND DIAGNOSES BEFORE CONCEPTION EVER
OCCURS. IT STARTED OFF LOOKING AT THINGS
337
00:34:29,700 --> 00:34:35,372
LIKE SINGLE GENE DISORDERS. IT'S EXPANDED
TREMENDOUSLY BECAUSE NOW WE'RE ABLE TO LOOK
338
00:34:35,506 --> 00:34:41,044
AT THE ACTUAL NUMBER OF CHROMOSOMES ON
AN EMBRYO. Narrator: THIS HAS ENHANCED
339
00:34:41,179 --> 00:34:48,085
THE TEAM'S ABILITY TO PREEMPTIVELY LOOK
AT DISEASES. WE'RE ABOUT 450 DISEASES
340
00:34:48,219 --> 00:34:55,926
RIGHT NOW. AS DIFFERENT DISEASE
INFORMATION COMES OUT WE'RE ABLE TO SCREEN
341
00:34:56,060 --> 00:35:02,165
MORE AND MORE FOR THOSE AS WELL. Narrator:
BUT THE POSSIBILITIES OF PGD TESTING GO
342
00:35:02,300 --> 00:35:07,304
FAR BEYOND MONITORING FOR HEALTH
DEFECTS. THE MOST COMMON SORT OF THE
343
00:35:07,438 --> 00:35:14,511
SIMPLEST USE IS IN GENDER
DETERMINATION. WE ANNOUNCED THE ABILITY TO
344
00:35:14,645 --> 00:35:20,817
DETERMINE EYE COLOR AND HAIR COLOR IN SELECTED
INDIVIDUALS. IN THE FUTURE, WE'RE GOING TO BE
345
00:35:20,952 --> 00:35:26,089
ABLE TO DETERMINE ULTIMATE HEIGHT, ULTIMATE
WEIGHT, PERHAPS ATHLETIC ABILITY, SKIN TONE,
346
00:35:26,224 --> 00:35:31,461
VOCAL CHARACTERISTICS FOR THOSE THAT WANT TO
SING WELL. WE HAVE THE ABILITY TO DETERMINE
347
00:35:31,596 --> 00:35:35,432
MORE AND MORE CHARACTERISTICS. ULTIMATELY
WE WILL BE ABLE TO DETERMINE HUNDREDS OF
348
00:35:35,566 --> 00:35:42,706
CHARACTERISTICS. Narrator: AFTER
BEING CAST OUT BY HIS CREATOR,
349
00:35:42,840 --> 00:35:46,120
FRANKENSTEIN'S MONSTER WANDERS THE EARTH
BUT IS REJECTED BY HUMANITY AT EVERY TURN.
350
00:35:46,210 --> 00:35:53,216
HE RETURNS TO VICTOR, DEMANDING HE CONSTRUCT
A COMPANION. FOR THE FIRST TIME VICTOR
351
00:35:53,351 --> 00:35:58,355
FRANKENSTEIN ACTUALLY FEELS SOME RESPONSIBILITY
FOR HIS CREATION AND STARTS CREATING A FEMALE
352
00:35:58,489 --> 00:36:02,459
CREATURE. BUT HALFWAY THROUGH, HE
STOPS. WHAT HE SAYS IS THAT SHE COULD
353
00:36:02,593 --> 00:36:08,665
BE MORE MALIGNANT THAN HER MATE, 10,000 TIMES
MORE MALIGNANT, HE SAYS, AND MOST THREATENING, SHE
354
00:36:08,799 --> 00:36:14,638
WILL BE ABLE TO PROCREATE. Narrator: FEARFUL
OF CREATING ANOTHER HORROR, VICTOR MAKES A
355
00:36:14,772 --> 00:36:19,643
DRAMATIC DECISION. AND TEARS TO PIECES
THE VERY CREATURE HE IS CONSTRUCTING.
356
00:36:19,777 --> 00:36:25,348
HE CAN'T DO THIS, BECAUSE THEN THEY WILL
REPRODUCE AND THEY WILL CREATE SOME KIND OF
357
00:36:25,483 --> 00:36:30,353
NEW RACE THAT WILL BE HORRIBLE TO
CONTEMPLATE. Narrator: SOME ARGUE
358
00:36:30,488 --> 00:36:38,488
FRANKENSTEIN HAS BECOME SYNONYMOUS
WITH SCIENCE OUT OF CONTROL.
359
00:36:38,896 --> 00:36:41,975
THE MONSTER THAT COULD DESTROY EVERYBODY,
IT CAN BE DESCRIBED AS A FRANKENSTEIN
360
00:36:41,999 --> 00:36:48,638
MOMENT. THE WORD FRANKENSTEIN
IMPLIES TECHNOLOGY GONE BERSERK.
361
00:36:48,773 --> 00:36:54,477
THAT THE BEST INTENTIONS OF SCIENTISTS
GO HAYWIRE AND TECHNOLOGY BITES BACK.
362
00:36:54,612 --> 00:36:58,481
Narrator: BUT IS THAT WHAT MARY
SHELLEY WAS REALLY TRYING TO SAY?
363
00:36:58,616 --> 00:37:04,154
I THINK HER ARGUMENT IS THAT IT'S OKAY
TO CREATE A NEW CREATURE, A NEW SPECIES,
364
00:37:04,288 --> 00:37:09,993
PROVIDED YOU TAKE RESPONSIBILITY
FOR IT. Narrator: TODAY
365
00:37:10,127 --> 00:37:14,130
ACCOUNTABILITY AND OVERSIGHT MECHANISMS ARE
IN PLACE TO ENSURE THAT SCIENTISTS CONDUCT
366
00:37:14,265 --> 00:37:22,265
THEIR RESEARCH RESPONSIBLY. MOST INSTITUTIONS
HAVE INSTITUTIONAL REVIEW BOARDS THAT
367
00:37:22,440 --> 00:37:26,042
REVIEW BOARD WILL LOOK AT WHAT'S PROPOSED
PROPOSED, THAT THE SCIENTIST HAS MADE EVERY
368
00:37:26,177 --> 00:37:30,480
POSSIBLE GOOD JUDGMENT ABOUT HOW TO MINIMIZE
THOSE RISKS. ETHICS COMES DOWN TO PEOPLE
369
00:37:30,615 --> 00:37:35,252
MAKING CHOICES AND CONSEQUENCES OF MAKING
THEIR CHOICES. VICTOR FRANKENSTEIN HAD THE
370
00:37:35,386 --> 00:37:40,023
BEST OF INTENTIONS. HE WANTED TO USE
THE MOST ADVANCED MEDICAL KNOWLEDGE OF
371
00:37:40,157 --> 00:37:45,295
HIS TIME TO ENHANCE THE HUMAN
CONDITION, TO ALLEVIATE SUFFERING.
372
00:37:45,429 --> 00:37:50,000
BUT HE DIDN'T THINK THROUGH THE CONSEQUENCES
OF HIS DISCOVERIES, AND THAT'S SOMETHING THAT
373
00:37:50,134 --> 00:37:53,603
SCIENTISTS ALSO HAVE TO CONSIDER.
WE LISTEN TO SOCIETY, WE
374
00:37:53,738 --> 00:37:57,374
LISTEN TO EVERYONE, WE ARE
SCIENTISTS. AND I THINK THE WORST THING IN
375
00:37:57,508 --> 00:38:03,913
THE WORLD YOU COULD EVER DO IS PUT HANDCUFFS
ON A SCIENTIST. Narrator: UNCERTAIN OF HOW
376
00:38:04,048 --> 00:38:09,319
HER OWN CREATION WOULD BE PERCEIVED, MARY
FIRST PUBLISHED HER NOVEL ANONYMOUSLY IN 1818
377
00:38:09,453 --> 00:38:14,190
AND THEN WAITED TO SEE HOW THE WORLD
WOULD RESPOND. MARY SHELLEY PUBLISHED
378
00:38:14,325 --> 00:38:19,462
"FRANKENSTEIN" ANONYMOUSLY BECAUSE WOMEN AT
THAT AGE WERE OFTEN AFRAID TO HAVE THEIR NAMES
379
00:38:19,597 --> 00:38:24,134
APPEAR IN PRINT. SHE DEDICATED
IT TO WILLIAM GODWIN, HER FATHER.
380
00:38:24,268 --> 00:38:27,971
HE HAD STOPPED SPEAKING TO HER WHEN SHE RAN
OFF WITH PERCY SHELLEY BUT SHE STILL WANTED TO
381
00:38:28,105 --> 00:38:31,975
HAVE SOMETHING IN PRINT THAT WOULD
BE WORTHY OF HER FAMOUS PARENTS.
382
00:38:32,109 --> 00:38:40,109
I HID MY HIDEOUS PROJECT INFORM AND
PROSPER. Narrator: AND THE STORY WOULD
383
00:38:41,919 --> 00:38:48,692
SOON TAKE ON A LIFE OF ITS
OWN. IT'S ALIVE! IT'S ALIVE!
384
00:38:48,826 --> 00:38:51,761
IT'S ALIVE!
385
00:39:00,771 --> 00:39:08,712
Narrator: AFTER FINISHING THE NOVEL "FRANKENSTEIN"
IN 1818, TRAGEDY CONTINUES TO PLAGUE MARY
386
00:39:08,846 --> 00:39:15,418
SHELLEY. SHE BECOMES
CONVINCED THAT SHE IS CURSED.
387
00:39:15,553 --> 00:39:19,789
AFTER SHE COMPLETES "FRANKENSTEIN,"
SHE AND PERCY CONTINUE TO LIVE IN ITALY.
388
00:39:19,924 --> 00:39:25,161
HAPPY ENOUGH, EXCEPT FOR THE
FACT THAT HER CHILDREN KEPT DYING.
389
00:39:25,296 --> 00:39:30,700
MARY HAD FIVE PREGNANCIES WITH PERCY
AND FOUR OF THOSE RESULTED IN EARLY DEATHS.
390
00:39:30,835 --> 00:39:35,905
THIS IS FINALLY CAPPED OF COURSE BY THE DEATH
BY DROWNING OF PERCY SHELLEY, THE DEATHS OF
391
00:39:36,040 --> 00:39:40,210
ALL HER CHILDREN, OF HER HUSBAND AT A VERY EARLY
AGE, LEFT HER AS A REALLY LIFE LONG PESSIMIST,
392
00:39:40,344 --> 00:39:43,680
MELON COLIC. SO IN THAT SENSE SHE LIVED
IN A WORLD BETWEEN THE LIVING AND THE
393
00:39:43,814 --> 00:39:48,618
DEAD. Narrator: FOLLOWING PERCY'S
DEATH IN 1823, MARY RETURNS TO
394
00:39:48,753 --> 00:39:53,323
LONDON AND DISCOVERS THAT IN HER ABSENCE
"FRANKENSTEIN" HAS BECOME AN ENORMOUS SUCCESS.
395
00:39:53,457 --> 00:39:58,728
IT IMMEDIATELY BECAME POPULAR,
WENT INTO SECOND, THIRD, FOURTH EDITIONS.
396
00:39:58,863 --> 00:40:03,533
SO POPULAR IN FACT THAT IN 1831 MARY SHELLEY
IMMEDIATELY LET EVERYONE KNOW THAT SHE WAS THE
397
00:40:03,667 --> 00:40:09,072
AUTHOR, AND THEREFORE, PUBLISHED ALL HER
WORKS AS "BY THE AUTHOR OF FRANKENSTEIN."
398
00:40:09,206 --> 00:40:14,978
Narrator: THE FIRST FILM ADAPTATION IS
BROUGHT TO FILM IN 1910 BY THE EDISON COMPANY,
399
00:40:15,112 --> 00:40:20,784
THOMAS EDISON CREDITED WITH
BRINGING ELECTRICITY TO THE MASSES.
400
00:40:20,918 --> 00:40:25,121
BUT IT WAS BORIS KARLOFF'S PORTRAYAL THAT
HAS ENDURED. THE JAMES WHALE FILM IS OF
401
00:40:25,256 --> 00:40:30,627
COURSE ICONIC, ALTHOUGH TREMENDOUSLY
MISLEADING. FORCE OF ALL, BORIS NEVER SPEAKS
402
00:40:30,761 --> 00:40:36,132
A WORD, WHEREAS IN THE NOVEL, THE CREATURE
DOMINATES, HIS VOICE DOMINATES THE TEXT.
403
00:40:36,267 --> 00:40:40,470
Narrator: NEARLY 200 YEARS LATER, THE TALE
HAS BEEN ADAPTED, REVAMPED, REIMAGINED,
404
00:40:40,604 --> 00:40:44,808
PARODIED AND RECOUNTED BY
405
00:40:48,179 --> 00:40:52,215
Narrator: NEARLY 200 YEARS LATER, THE TALE
HAS BEEN ADAPTED, REVAMPED, REIMAGINED,
406
00:40:52,349 --> 00:40:57,921
PARODIED AND RECOUNTED BY COUNTLESS
ARTISTS ON EVERY CORNER OF THE GLOBE.
407
00:40:58,055 --> 00:41:05,728
YOU CAN ALWAYS JUST SAY THE PHRASE
FRANKENSTEIN. DON'T GET INTO A FRANKENSTEIN
408
00:41:05,863 --> 00:41:13,303
MOMENT AND PEOPLE WILL UNDERSTAND WHAT
YOU MEAN. SO IT'S BECOME AN IMPORTANT PART
409
00:41:13,437 --> 00:41:16,840
OF OUR CULTURE. Narrator: WHEN MARY
SHELLEY CREATED VICTOR FRANKEN STEIN AND
410
00:41:16,974 --> 00:41:19,614
HIS MONSTER, SHE CREATED NOT ONLY
A PHENOMENON BUT AN ENTIRE GENRE.
411
00:41:19,643 --> 00:41:24,781
MARY SHELLEY IS USUALLY SEEN AS
THE VERY FIRST WRITER OF SCIENCE FICTION.
412
00:41:24,915 --> 00:41:28,618
BECAUSE SHE COMBINES THE THREE ELEMENTS THAT
HAVE TO BE IN ANY GREAT SCIENCE FICTION NOVEL.
413
00:41:28,752 --> 00:41:34,991
IT GIVES YOU A PLAUSIBLE ACCOUNT OF THE SCIENCE
OF THE DAY, IT GIVES YOU A HUMANISTIC CRITIQUE
414
00:41:35,125 --> 00:41:42,532
OF THAT SCIENCE, AND IT ALSO GIVES YOU A VIABLE
PREDICTION OF WHAT'S LIKELY TO HAPPEN IF THE
415
00:41:42,666 --> 00:41:50,340
WAYS OF SCIENCE AND TECHNOLOGY ARE NOT IN SOME
WAYS CONTROLLED. I WOULD CONSIDER MARY SHELLEY
416
00:41:50,474 --> 00:41:56,579
TO BE ONE OF THE GREAT PROPHETS OF SCIENCE
FICTION. NOT ONLY DID SHE WRITE A NOVEL
417
00:41:56,714 --> 00:42:01,851
THAT WOULD SCARE THE PANTS OFF YOUNG KIDS, IT'S
ALSO A MORALITY TALE THAT GOES TO THE HEART OF
418
00:42:01,986 --> 00:42:09,986
THE PURPOSE OF TECHNOLOGY. Narrator: IN 1851,
AT THE AGE OF 53, MARY SHELLEY DIES OF A
419
00:42:10,294 --> 00:42:18,294
SUSPECTED BRAIN TUMOR. WHILE SHE WAS STILL
A TEENAGER, MARY SHELLEY CREATED AN ENTIRE
420
00:42:20,271 --> 00:42:26,342
LITERARY GENRE. SHE WAS A REBEL AND
AN OUTSIDER WHOSE LIFE WAS MARKED BY A
421
00:42:26,477 --> 00:42:32,982
SPECTER OF DEATH AND A PASSION FOR
KNOWLEDGE. IN CREATING HER MONSTER, MARY
422
00:42:33,117 --> 00:42:40,189
SHELLEY CREATED A MASTERPIECE. I THINK IT
ECHOES ON THE QUESTIONS THAT ECHO WITH ALL OF
423
00:42:40,324 --> 00:42:46,629
US IN WHO MADE US AND WHERE ARE WE GOING TO
GO AFTERWARDS. "FRANKENSTEIN" IS SYNONYMOUS
424
00:42:46,764 --> 00:42:50,033
WITH TECHNOLOGY GONE AMOK. BUT THE TRUE
MEANING OF THE ORIGINAL STORY IS MUCH MORE
425
00:42:50,167 --> 00:42:56,506
COMPLEX. MARY SHELLEY ASKED, IS IT
REALLY WRONG FOR SCIENCE TO CREATE
426
00:42:56,640 --> 00:42:59,642
LIFE.48101
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