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1
00:00:07,073 --> 00:00:09,974
AII right, hold on.
I got the turn up here.
2
00:00:11,244 --> 00:00:12,541
(WHOOPING)
3
00:00:18,218 --> 00:00:20,743
Oh! How cool was that?
4
00:00:20,820 --> 00:00:22,651
That was way cool!
5
00:00:27,427 --> 00:00:29,759
My turn. Sorry, that's
not allowed.
6
00:00:29,829 --> 00:00:31,694
I just signed
15 pages of forms saying
7
00:00:31,765 --> 00:00:34,859
you gotta ride
on the back of that thing.
I don't see
any Iawyers around.
8
00:00:34,934 --> 00:00:36,925
You know
that's not the point.
No.
9
00:00:37,003 --> 00:00:39,938
You just wanna keep
all the fun to yourself.
10
00:00:40,974 --> 00:00:42,464
Come on, Dad!
11
00:00:43,576 --> 00:00:46,044
You go over 15,
we're pulling over, all right?
I mean it.
12
00:00:46,112 --> 00:00:48,410
You're the best.
AII right, get on there.
13
00:00:48,481 --> 00:00:50,574
Put on your goggles.
Okay.
14
00:00:51,518 --> 00:00:53,543
Ready?
Got the clutch in?
15
00:00:53,620 --> 00:00:55,645
AII right, that's my boy.
16
00:00:58,425 --> 00:01:00,552
(WHOOPING)
17
00:01:09,402 --> 00:01:12,235
Adam, you're going too fast,
slow it down!
18
00:01:15,375 --> 00:01:18,367
I mean it,
you're going too fast.
SIow down!
19
00:01:18,445 --> 00:01:19,707
Adam!
20
00:01:25,018 --> 00:01:26,110
Adam!
21
00:01:27,754 --> 00:01:29,654
Let go of the throttle!
22
00:01:33,893 --> 00:01:35,019
Adam!
23
00:01:35,395 --> 00:01:37,192
Adam! No!
24
00:02:12,198 --> 00:02:14,689
PARAMEDIC: What've you got?
Sixteen-year-old, status post,
25
00:02:14,767 --> 00:02:16,632
ATV crash,
40% burns on his body.
26
00:02:16,703 --> 00:02:18,136
Nasotracheal intubation.
27
00:02:18,204 --> 00:02:19,933
Start a bag
of Iactated Ringer's,
wide open...
28
00:02:20,006 --> 00:02:22,201
Will he be okay?
We'II be with you when we can.
29
00:02:22,275 --> 00:02:23,674
Get him out!
30
00:02:24,043 --> 00:02:25,670
Wait, wait, wait!
31
00:02:25,912 --> 00:02:29,006
NURSE: I'II start fluids.
Let's go get him hooked up.
32
00:02:30,817 --> 00:02:32,375
SURGEON: Watch the Iine.
33
00:02:44,230 --> 00:02:45,720
(READING HINDI)
34
00:02:51,104 --> 00:02:53,937
Been Iooking for you.
Been avoiding you.
35
00:02:54,174 --> 00:02:55,300
Burn Unit can handle it.
36
00:02:55,375 --> 00:02:58,936
If they could handle it,
they wouldn't
be asking for you.
37
00:03:00,813 --> 00:03:03,043
Is that a journal?
Friend wrote an article.
38
00:03:03,116 --> 00:03:04,276
In Hindi?
39
00:03:04,350 --> 00:03:07,581
They have a cutting-edge
neuroscience program in India.
40
00:03:07,654 --> 00:03:09,884
It says so right on the cover.
41
00:03:13,726 --> 00:03:15,853
Kid's heart rate's messed.
42
00:03:15,929 --> 00:03:18,295
Tachycardia
can be explained by the burn.
43
00:03:18,364 --> 00:03:20,798
I assume
the Burn Unit knew that.
44
00:03:23,136 --> 00:03:24,831
His potassium's Iow.
45
00:03:24,904 --> 00:03:26,838
Which can also be explained
by the burn.
46
00:03:26,906 --> 00:03:29,431
Except I'm sure
the Burn Unit's
pumping him with fluids
47
00:03:29,509 --> 00:03:32,103
which means his potassium
should be going up, not down.
48
00:03:32,178 --> 00:03:33,736
Could be amphetamines.
49
00:03:33,813 --> 00:03:35,678
Or bacteria
Iunching on his heart.
50
00:03:35,748 --> 00:03:39,081
Or cardiomyopathy,
or some other very bad thing.
51
00:03:39,152 --> 00:03:40,779
HOUSE: He needs an EKG.
52
00:03:43,056 --> 00:03:44,045
(EXCLAIMING)
53
00:03:47,760 --> 00:03:50,888
Okay, no skin, no EKG.
54
00:03:50,964 --> 00:03:53,398
CHASE: Is he even
gonna survive the burn?
55
00:03:53,566 --> 00:03:55,693
What, you got
a date or something?
56
00:03:56,202 --> 00:03:58,363
Forty percent of his body.
57
00:03:58,438 --> 00:04:00,906
If the Burns Unit
can prevent an infection,
58
00:04:00,974 --> 00:04:03,033
his body will regenerate
maybe 10%,
59
00:04:03,109 --> 00:04:05,873
surgeons will do
20 or so grafts,
six months in this room,
60
00:04:05,945 --> 00:04:09,506
he'II end up
with a series of nasty scars,
maybe some pain,
61
00:04:09,582 --> 00:04:10,981
but he'II Iive.
62
00:04:11,584 --> 00:04:12,983
Unless his heart shuts down
63
00:04:13,052 --> 00:04:17,648
'cause we can't figure out
what's causing the
Iow potassium and tachycardia.
64
00:04:18,458 --> 00:04:21,859
We need help
from a Belgian doc
named Einthoven.
65
00:04:21,928 --> 00:04:23,259
He's dead.
66
00:04:23,329 --> 00:04:27,197
While he was alive,
he invented a Iittle dittie
called the Galvanometer.
67
00:04:27,267 --> 00:04:28,325
Where do we get one?
68
00:04:28,401 --> 00:04:31,962
Go to any electronics store
that's been open
since before 1905.
69
00:04:32,038 --> 00:04:36,099
There's a good chance
they've got one
in a corner in the basement.
70
00:04:37,410 --> 00:04:39,844
BRENDA: We need
an audio-visual setup
for the Iecture hall.
71
00:04:39,912 --> 00:04:41,846
What for?
For the Iecture.
72
00:04:41,914 --> 00:04:44,405
What Iecture?
Dr. Weber's Iecture.
73
00:04:44,651 --> 00:04:47,984
Who is Dr. Weber?
A neurologist, I think.
74
00:04:48,621 --> 00:04:50,521
The memo was from you.
75
00:04:56,863 --> 00:04:59,127
Where is my assistant?
She Ieft.
76
00:04:59,198 --> 00:05:00,358
When?
Wednesday.
77
00:05:00,433 --> 00:05:02,731
Seriously?
Well, the temp agency
sent someone,
78
00:05:02,802 --> 00:05:04,064
but she got Iost.
79
00:05:04,137 --> 00:05:06,628
Well, when she gets here,
fire her.
80
00:05:27,260 --> 00:05:28,887
Oh, yeah.
81
00:05:28,961 --> 00:05:31,691
Did you issue this memo?
Look at that.
82
00:05:33,633 --> 00:05:34,930
Congratulations.
83
00:05:35,001 --> 00:05:37,299
The patient
that has been in a coma
for two years and counting
84
00:05:37,370 --> 00:05:38,701
is still in a coma.
85
00:05:38,771 --> 00:05:40,500
This is not my signature.
86
00:05:40,573 --> 00:05:42,165
I don't know
anything about this guy.
87
00:05:42,241 --> 00:05:45,108
I'm supposed to introduce him?
Have Iunch?
88
00:05:46,913 --> 00:05:49,780
The coma patient
has a migraine?
Oh, no, no, no.
89
00:05:49,849 --> 00:05:52,181
No, I gave him medication
to prevent a migraine.
90
00:05:52,251 --> 00:05:53,718
That's a migraine.
91
00:05:53,786 --> 00:05:56,084
Increased flow velocity
in his cerebral arteries.
92
00:05:56,155 --> 00:05:58,817
I did subsequently
give him nitroglycerin,
which could possibly...
93
00:05:58,891 --> 00:06:03,021
You induced
a migraine headache
in a coma patient?
94
00:06:03,096 --> 00:06:06,759
I gave him a Iittle headache,
similar to the one
you're giving me now.
95
00:06:06,833 --> 00:06:09,393
Have you even read
an ethical guideline?
96
00:06:09,469 --> 00:06:12,438
Well, it would be wrong
to try out a new
migraine prevention medication
97
00:06:12,505 --> 00:06:14,735
on someone
who can actually feel pain.
98
00:06:14,807 --> 00:06:17,901
Did you sign this?
Yeah.
99
00:06:19,345 --> 00:06:22,712
We can talk Iater about
the appropriate discipline.
100
00:06:26,185 --> 00:06:27,277
CAMERON: Because of the burn,
101
00:06:27,353 --> 00:06:29,821
we can't perform
any of our normal tests
to see what's wrong.
102
00:06:29,889 --> 00:06:32,483
So we're going to try
a Galvanometer.
103
00:06:33,159 --> 00:06:36,322
It picks up a pulse
in the wrists and the ankles.
104
00:06:36,662 --> 00:06:39,859
Hopefully it'II tell us
why his heart rhythm
is abnormal.
105
00:06:39,932 --> 00:06:43,197
What have I done to him? I...
It was an accident.
106
00:06:43,903 --> 00:06:45,495
AII right? So...
107
00:06:46,439 --> 00:06:47,770
He's got all these burns
108
00:06:47,840 --> 00:06:50,035
and now
there's something wrong
with his heart?
109
00:06:50,109 --> 00:06:52,873
We're trying to figure out
if the two
are somehow connected.
110
00:06:52,945 --> 00:06:55,937
Had he been sick Iately?
No, nothing.
111
00:06:56,015 --> 00:06:57,642
Anything unusual
with his behavior?
112
00:06:57,717 --> 00:06:59,412
Had he been tired a Iot?
Nothing.
113
00:06:59,485 --> 00:07:03,615
He was great, he was happy,
he was just having
a great time, and then...
114
00:07:03,689 --> 00:07:07,318
If he was experimenting
with amphetamines
or cocaine...
115
00:07:07,393 --> 00:07:08,451
No.
116
00:07:09,095 --> 00:07:11,825
We gave him some pot
about a year ago, to try...
117
00:07:11,898 --> 00:07:13,422
It was just once.
118
00:07:13,499 --> 00:07:16,059
We thought
if we took the mystery
out of drugs and alcohol,
119
00:07:16,135 --> 00:07:17,466
the Iess he'd experiment.
120
00:07:17,537 --> 00:07:19,869
We'II know more
after the tests.
121
00:07:21,774 --> 00:07:24,709
It Iooks Iike
they're gonna electrocute him.
122
00:07:25,912 --> 00:07:27,311
PIug it in.
123
00:07:28,815 --> 00:07:30,339
You plug it in.
124
00:07:30,950 --> 00:07:32,884
Fine. Give me the cord.
125
00:07:39,792 --> 00:07:41,020
Works.
126
00:07:43,463 --> 00:07:44,896
Prominent U waves.
127
00:07:44,964 --> 00:07:47,865
No inverted T wave.
No ischemia.
128
00:07:48,067 --> 00:07:49,694
Q wave normal.
129
00:07:50,603 --> 00:07:52,230
That's not good.
130
00:07:55,942 --> 00:07:58,274
Okay, turn it off.
Turn it off!
131
00:07:58,344 --> 00:08:00,278
What's happening?
What is that?
132
00:08:00,346 --> 00:08:01,574
CHASE: The seizure's
getting...
133
00:08:01,647 --> 00:08:03,410
Can't you stop that?
134
00:08:09,889 --> 00:08:11,686
Who electrocuted my patient?
135
00:08:11,757 --> 00:08:13,691
He had a seizure.
CAMERON: He wasn't
electrocuted.
136
00:08:13,759 --> 00:08:16,421
What does the seizure tell us?
Move.
137
00:08:16,496 --> 00:08:17,724
What are you Iooking for?
138
00:08:17,797 --> 00:08:21,563
Same as you are, Iove,
acceptance,
solid return on an investment.
139
00:08:21,634 --> 00:08:23,226
Differential diagnosis. Go.
140
00:08:23,302 --> 00:08:25,202
Could be epilepsy
or seizure disorder.
141
00:08:25,271 --> 00:08:28,638
Not with the tachycardia.
It could be
a virus in his brain.
142
00:08:28,708 --> 00:08:31,006
Your specificity's impressive.
143
00:08:31,077 --> 00:08:32,601
Adrenoleukodystrophy.
144
00:08:32,678 --> 00:08:33,975
Could be MS.
145
00:08:34,046 --> 00:08:36,708
The seizures could be caused
by plaques
and Iesions on the brain.
146
00:08:36,782 --> 00:08:39,410
Well, Iet's find out which.
Get him an MRI.
147
00:08:39,485 --> 00:08:41,248
No nuclear imaging!
148
00:08:43,022 --> 00:08:47,322
He wouldn't survive
the move to Radiology.
MRI and CT scan are both out.
149
00:08:47,393 --> 00:08:50,624
Okay, Iumbar puncture
will tell us
if his proteins are elevated,
150
00:08:50,696 --> 00:08:52,027
at Ieast we can exclude MS.
151
00:08:52,164 --> 00:08:54,132
We can't do
a Iumbar puncture either.
152
00:08:55,801 --> 00:08:57,860
You're cramping my exits.
153
00:08:57,937 --> 00:08:59,768
Don't tell me,
no skin on his spine.
154
00:08:59,839 --> 00:09:02,774
We'd be inserting a needle
into an area
that's teeming with bacteria.
155
00:09:02,842 --> 00:09:05,675
If he doesn't have
a brain infection already,
we'd give him one for sure.
156
00:09:05,745 --> 00:09:08,475
There's no other way
to Iook at a brain.
157
00:09:09,348 --> 00:09:11,612
Transcranial
Doppler Sonography.
158
00:09:11,684 --> 00:09:14,847
She said "brain,"
not "pregnant woman's uterus."
159
00:09:14,921 --> 00:09:17,685
They do sound alike.
I used one to Iook at a brain
this morning.
160
00:09:17,757 --> 00:09:20,419
Why didn't you take
the patient to Radiology,
get an MRA?
161
00:09:20,493 --> 00:09:22,586
Obviously
I was doing something illegal.
162
00:09:22,662 --> 00:09:24,926
Using nuclear imaging
would have raised questions.
163
00:09:24,997 --> 00:09:27,795
You're not gonna get
a diagnosis of MS
from a sonogram.
164
00:09:27,867 --> 00:09:29,926
Not definitively,
but patients with MS
165
00:09:30,002 --> 00:09:33,096
have more reactive neurons
in their occipital cortex.
166
00:09:36,909 --> 00:09:38,240
Okay then.
167
00:09:41,347 --> 00:09:44,282
Thank you for all coming
to today's Iecture
168
00:09:44,350 --> 00:09:46,409
by Dr. Phillip Weber,
169
00:09:46,852 --> 00:09:49,480
who is our guest today
at our hospital
170
00:09:49,555 --> 00:09:53,082
to talk about headaches.
171
00:09:54,226 --> 00:09:57,957
Dr. Weber is at
the Weber Center for Pain,
that makes sense.
172
00:09:58,364 --> 00:10:01,162
Weber, Weber.
So please welcome Dr. Weber!
173
00:10:08,608 --> 00:10:11,668
Thank you Dr. Cuddy.
174
00:10:11,844 --> 00:10:13,744
(AUDIENCE LAUGHING)
175
00:10:13,913 --> 00:10:17,610
I suppose I should tell you
a Iittle bit more
about myself.
176
00:10:18,384 --> 00:10:20,682
I went to school in Virginia.
177
00:10:21,687 --> 00:10:23,678
You've never been
to one of these things
in your Iife.
178
00:10:23,756 --> 00:10:26,281
Who is this guy?
No idea.
179
00:10:27,627 --> 00:10:29,527
What's with the outfit?
180
00:10:29,962 --> 00:10:32,760
Sudden chills
and Iight sensitivity.
181
00:10:33,165 --> 00:10:34,632
Inexplicable.
182
00:10:35,468 --> 00:10:39,063
I received my medical degree
at Johns Hopkins University,
183
00:10:39,505 --> 00:10:42,440
where I studied under
Brightman and Gilmar...
184
00:10:42,541 --> 00:10:44,338
Hmm. He must be good.
185
00:10:44,410 --> 00:10:47,436
You went to Hopkins,
and studied
under Brightman and Gilmar.
186
00:10:47,513 --> 00:10:48,912
Shh.
187
00:10:48,981 --> 00:10:52,382
...helped me win
the Doyle Internship
at the Mayo CIinic.
188
00:10:52,451 --> 00:10:55,443
You were supposed
to get the Doyle Internship.
189
00:10:57,890 --> 00:11:01,485
This guy's Von Lieberman?
The guy who got you
thrown out for cheating?
190
00:11:01,560 --> 00:11:05,291
The dean threw me out.
Von Lieberman
just ratted on me.
191
00:11:05,364 --> 00:11:07,594
This guy's name is Weber,
not Von Lieberman.
192
00:11:07,667 --> 00:11:10,864
I call Weber Von Lieberman,
way eviler.
193
00:11:11,404 --> 00:11:12,393
Shh.
194
00:11:13,439 --> 00:11:17,535
...1 D receptors have improved
the acute treatment
of migraines,
195
00:11:18,411 --> 00:11:19,969
to this point...
196
00:11:20,046 --> 00:11:21,604
So what's the plan?
197
00:11:21,681 --> 00:11:25,242
You gonna wait
until he bends over
and make a fart sound?
198
00:11:25,484 --> 00:11:29,386
I'm not here about the past.
He's a bad scientist.
199
00:11:30,489 --> 00:11:33,424
Well, you cheated off him,
how bad can he be?
200
00:11:34,894 --> 00:11:36,862
He got the answer wrong.
201
00:11:44,637 --> 00:11:46,298
DOUG: Are they trying
to wake him up?
202
00:11:46,372 --> 00:11:48,602
They can't do that, right?
He'II be in too much pain.
203
00:11:48,674 --> 00:11:50,972
Don't worry, he's still under.
204
00:11:51,043 --> 00:11:54,308
But the brain
never completely sleeps,
it's always working.
205
00:11:54,380 --> 00:11:57,872
Controlling your heart rate,
breathing, temperature.
206
00:11:59,051 --> 00:12:01,076
The eyes
respond to visual stimuli.
207
00:12:01,153 --> 00:12:03,121
BIood flow increases
in certain areas of the brain
208
00:12:03,189 --> 00:12:05,680
and we can track that
with a sonogram.
209
00:12:05,758 --> 00:12:10,218
With MS, blood vessels
are more reactive,
so flow is faster.
210
00:12:10,429 --> 00:12:12,488
If Adam has an infection,
211
00:12:12,665 --> 00:12:15,099
there'd be swelling,
which would
constrict the arteries.
212
00:12:15,167 --> 00:12:17,397
And the flow would be slower.
213
00:12:17,470 --> 00:12:20,303
Chase.
Near the subarachnoid space.
214
00:12:26,612 --> 00:12:30,639
WEBER: Data from
control subjects were analyzed
of a two-way ANOVA
215
00:12:30,716 --> 00:12:33,810
with status and side
as within-subject factors.
216
00:12:35,321 --> 00:12:39,018
You stalked this guy
for 20 years just for
this shot to humiliate him?
217
00:12:39,091 --> 00:12:41,059
I'm trying to Iearn.
218
00:12:41,127 --> 00:12:43,459
...vessels without
significant rebound...
219
00:12:43,529 --> 00:12:46,191
He doesn't even know
what that means.
220
00:12:46,265 --> 00:12:47,732
You're gonna interrupt him,
aren't you?
221
00:12:47,833 --> 00:12:49,425
If I have a question.
222
00:12:49,502 --> 00:12:51,470
And what's that
gonna accomplish?
223
00:12:51,537 --> 00:12:55,303
Why can't you just enjoy this?
Why can't you just
be happy for me?
224
00:12:55,374 --> 00:12:59,708
You have got to find
Iess debilitating outlets
than humiliating people.
225
00:12:59,779 --> 00:13:03,215
I hear bowling is more fun
than stalking.
226
00:13:03,816 --> 00:13:05,306
But I'm better at this.
227
00:13:05,384 --> 00:13:07,852
...if "P" is Iess than
point-zero...
228
00:13:07,920 --> 00:13:10,411
BIow a ton of money
on a plasma TV.
229
00:13:11,824 --> 00:13:14,054
We found a subarachnoid bleed.
230
00:13:15,394 --> 00:13:17,862
BIeed in the head
isn't causing seizures.
231
00:13:17,930 --> 00:13:21,229
It could be. 10% with damage
to cerebral cortex
have a seizure.
232
00:13:21,300 --> 00:13:22,858
Or bacterial meningitis.
233
00:13:22,935 --> 00:13:25,165
Viral encephalitis?
There's no way
to tell without...
234
00:13:25,237 --> 00:13:26,465
Shut up!
235
00:13:27,673 --> 00:13:29,072
Excuse me.
236
00:13:30,342 --> 00:13:31,604
Not you.
237
00:13:31,677 --> 00:13:35,340
You know, if my Iecture
is interrupting your meeting,
I can wait.
238
00:13:35,414 --> 00:13:36,813
(SPEAKING HINDI)
239
00:13:38,350 --> 00:13:41,342
As your people say in India.
Appreciate it.
240
00:13:41,420 --> 00:13:44,981
We'II figure out why Iater.
Fix the bleed or he dies.
241
00:13:45,057 --> 00:13:47,287
Talk to you in a couple hours.
242
00:13:49,962 --> 00:13:51,156
(SPEAKING HINDI)
243
00:14:01,440 --> 00:14:03,670
I'm in the subarachnoid space.
244
00:14:04,777 --> 00:14:07,041
Can you get it?
Think so.
245
00:14:09,415 --> 00:14:11,406
Put the probe
back where it was
so I can see the wire!
246
00:14:11,483 --> 00:14:12,575
We're Iooking for the bleed
in...
247
00:14:12,651 --> 00:14:16,781
Look when I get there,
I'm flying blind
without a contrast CT here!
248
00:14:26,031 --> 00:14:30,400
...and with a p-value
of Iess than 0.001,
249
00:14:30,736 --> 00:14:35,105
we have strong statistical
evidence that this drug
prevents migraine headaches
250
00:14:35,174 --> 00:14:37,540
without daily administration.
251
00:14:38,177 --> 00:14:39,735
Excuse me, Doctor.
252
00:14:39,812 --> 00:14:41,473
He knows his field
better than you do.
253
00:14:41,547 --> 00:14:45,506
It's always been
my understanding that, unless
you follow a daily regimen,
254
00:14:45,584 --> 00:14:47,609
no drug
can prevent a migraine.
255
00:14:47,686 --> 00:14:49,586
That's why they call it
a breakthrough.
256
00:14:49,655 --> 00:14:51,850
That's why
you call it a breakthrough.
257
00:14:51,924 --> 00:14:55,223
No, the pharmaceutical company
sponsoring my clinical trials
258
00:14:55,294 --> 00:14:57,524
also hails it
as a breakthrough.
259
00:14:57,596 --> 00:15:00,224
I'm sure your wife
and Iawyer do, too.
260
00:15:01,467 --> 00:15:03,765
Is there anybody
who doesn't stand
to make a fortune from it
261
00:15:03,836 --> 00:15:05,303
calling it a breakthrough?
262
00:15:05,371 --> 00:15:06,531
Who are you?
263
00:15:06,605 --> 00:15:09,096
Just a Iunatic
who desperately needs a hobby.
264
00:15:09,174 --> 00:15:11,165
How exactly
do these studies work?
265
00:15:11,243 --> 00:15:13,177
Do you give this drug
to a bunch of people,
266
00:15:13,245 --> 00:15:16,874
and if they don't
get a migraine, you go,
"Voila, my drug works"?
267
00:15:16,949 --> 00:15:18,541
Excuse me, miss?
268
00:15:18,918 --> 00:15:20,681
Do you have cancer?
269
00:15:22,254 --> 00:15:25,223
Wow! Mango juice
prevents cancer.
270
00:15:25,691 --> 00:15:28,888
Perhaps I should have
taken my medication
before this Iecture.
271
00:15:31,063 --> 00:15:35,397
WEBER: We had
a very specific control group,
chronic migraine sufferers.
272
00:15:35,467 --> 00:15:37,594
I don't have time
to go through
all the math right now,
273
00:15:37,670 --> 00:15:41,128
but the incidence
was dramatically...
Sure, in India.
274
00:15:41,740 --> 00:15:44,402
Two plus two
equals five there, right?
275
00:15:45,411 --> 00:15:46,673
Do I know you?
276
00:15:46,745 --> 00:15:50,340
I know your math skills.
They blow.
277
00:15:50,916 --> 00:15:52,110
Touche.
278
00:15:52,184 --> 00:15:54,084
You sound very familiar.
279
00:15:54,153 --> 00:15:57,020
Why did you publish it
in an obscure journal
in India?
280
00:15:57,089 --> 00:16:01,583
Why not publish it
in really, really cool
head cases of South Philly?
281
00:16:01,660 --> 00:16:04,356
Neuroscience New Delhi
is a respected journal.
282
00:16:04,430 --> 00:16:08,093
Yeah.
The guy running SIurp N' Gulp
tells me it's one of the best.
283
00:16:08,167 --> 00:16:10,101
Get a hooker, anything.
284
00:16:10,169 --> 00:16:13,764
See, I'm thinking
that publishing studies
is probably the easiest way
285
00:16:13,839 --> 00:16:16,467
to get
a pharmaceutical company
to give you a reach-around.
286
00:16:16,542 --> 00:16:19,636
And choosing a journal
that no one can actually read,
well, that's...
287
00:16:19,712 --> 00:16:20,906
That's shrewd.
288
00:16:20,980 --> 00:16:24,746
I know I know you.
Sure you do, Dick.
289
00:16:25,217 --> 00:16:26,275
The name's Philip.
290
00:16:26,385 --> 00:16:29,445
My bad. Something to do
with your face.
291
00:16:29,521 --> 00:16:31,751
I always think
your name is Dick.
292
00:16:31,824 --> 00:16:33,815
House?
Here.
293
00:16:35,761 --> 00:16:39,595
Medical school
was 20 years ago.
Give it a rest. Grow up.
294
00:16:39,665 --> 00:16:44,432
Yeah. You were always
the grown-up. Do the
responsible thing, tattletale!
295
00:16:44,903 --> 00:16:47,895
You cheated!
I cheated then,
you're cheating now!
296
00:16:47,973 --> 00:16:49,031
Your drug doesn't work.
297
00:16:49,108 --> 00:16:52,600
Oh, yes, you would Iike to
believe that because it plays
right into your fantasy...
298
00:16:52,678 --> 00:16:54,669
I tested it.
Oh, really?
299
00:16:55,014 --> 00:16:57,949
What are your parameters?
Where's your study?
300
00:17:00,452 --> 00:17:02,044
Room 2134.
301
00:17:02,354 --> 00:17:04,652
One patient?
The coma patient?
302
00:17:05,924 --> 00:17:07,949
You haven't changed a bit.
303
00:17:08,727 --> 00:17:12,595
You took shortcuts
in med school,
you're taking shortcuts now.
304
00:17:12,798 --> 00:17:16,063
You cannot test this
on an abnormal brain.
305
00:17:16,135 --> 00:17:20,162
That's so close-minded.
He's not abnormal,
he's special.
306
00:17:20,239 --> 00:17:23,675
Cerebral cortex
atrophies in coma patients.
307
00:17:25,577 --> 00:17:28,239
You need Iive,
conscious people.
308
00:17:31,917 --> 00:17:34,351
You don't know everything,
House!
309
00:17:38,424 --> 00:17:41,154
FOREMAN: Something
that disrupts brain function.
310
00:17:41,427 --> 00:17:44,863
PIaques are perfect.
Interrupt
neuronal communication.
311
00:17:44,930 --> 00:17:47,262
MS?
No, MS is complicated.
312
00:17:47,332 --> 00:17:51,166
I think this is more basic.
It's just tachycardia
and seizures.
313
00:17:51,236 --> 00:17:54,296
How much Ionger
the Burn Unit guys
gonna keep him in that thing?
314
00:17:54,373 --> 00:17:57,274
Lecture's over, Iet's go.
House wants to...
315
00:18:00,179 --> 00:18:01,840
Adam's waking up.
316
00:18:02,247 --> 00:18:04,044
Get the anesthesiologist
in here now.
317
00:18:04,116 --> 00:18:05,413
CAMERON: He's in pain.
318
00:18:07,019 --> 00:18:08,884
That's not pain.
319
00:18:09,621 --> 00:18:11,555
Need some help in here!
320
00:19:13,452 --> 00:19:15,215
Adam had an orgasm.
321
00:19:17,022 --> 00:19:19,820
What? You mean,
while he was sedated...
322
00:19:21,860 --> 00:19:22,849
(HOUSE EXCLAIMING)
323
00:19:26,365 --> 00:19:27,832
What's wrong?
324
00:19:29,401 --> 00:19:31,369
I'm having a migraine.
325
00:19:31,770 --> 00:19:33,237
Are you okay?
326
00:19:34,773 --> 00:19:35,865
Yes.
327
00:19:37,643 --> 00:19:39,076
I was right.
328
00:19:41,213 --> 00:19:42,202
(GROANING)
329
00:19:49,888 --> 00:19:52,015
I'm gonna knock you out
for a couple of hours.
330
00:19:52,090 --> 00:19:53,887
No, I got work to do.
331
00:19:54,259 --> 00:19:57,092
Just give me sumatriptan
for the pain
332
00:19:57,162 --> 00:19:59,653
and verapamil
so it doesn't recur.
333
00:20:03,335 --> 00:20:06,930
I heard the patient had fun
in the hyperbaric chamber.
334
00:20:07,005 --> 00:20:08,131
Yeah.
335
00:20:08,207 --> 00:20:10,801
Gotta schedule me
some time in there.
336
00:20:13,478 --> 00:20:16,311
Weber's meds
aren't even Iegal in the U.S.
337
00:20:16,548 --> 00:20:18,311
It's Iegal in India.
338
00:20:19,751 --> 00:20:21,446
I was disoriented.
339
00:20:27,359 --> 00:20:29,520
Moving around is a bad idea.
340
00:20:29,895 --> 00:20:32,557
Hey, if you feel chest pain,
you need to Iet me know.
341
00:20:32,631 --> 00:20:35,566
Verapamil can cause
congestive heart failure.
342
00:20:35,701 --> 00:20:37,726
Nothing can hurt my heart.
343
00:20:40,839 --> 00:20:45,173
Hey, you're gonna feel
some dizziness. Definitely
gonna be constipated.
344
00:20:49,748 --> 00:20:53,582
Differential diagnosis
for getting off.
345
00:20:54,386 --> 00:20:57,753
Is he gonna be okay?
No. Something's
seriously wrong with him.
346
00:20:57,823 --> 00:21:02,385
Differential diagnosis
for ejaculation.
347
00:21:04,763 --> 00:21:06,390
Don't make me say it again.
348
00:21:06,465 --> 00:21:08,626
We're not stalling,
we just don't know.
349
00:21:08,700 --> 00:21:10,065
Then guess.
350
00:21:10,869 --> 00:21:13,667
Could pain medication
cause an orgasm?
I wish.
351
00:21:13,739 --> 00:21:15,707
Maybe pain caused the orgasm.
352
00:21:15,774 --> 00:21:19,210
You get a tattoo,
the brain releases endorphins
which create pleasure.
353
00:21:19,278 --> 00:21:21,838
Most people don't orgasm
from a needle prick.
354
00:21:21,913 --> 00:21:23,778
HOUSE: Well,
Chase has a point.
355
00:21:23,849 --> 00:21:27,546
The brain
is Iike a huge train station,
if the switches...
356
00:21:28,453 --> 00:21:29,442
(GROANING)
357
00:21:30,856 --> 00:21:32,824
You're the neurologist,
talk for me.
358
00:21:32,891 --> 00:21:36,987
If sensory information
got misinterpreted by
the medial forebrain bundle,
359
00:21:37,062 --> 00:21:39,997
it's possible
for bad to feel good,
and good to feel bad.
360
00:21:40,065 --> 00:21:43,728
He's a Iucky kid.
Let's not fix him
until the burns heal.
361
00:21:43,802 --> 00:21:45,861
So what attacks
the medial forebrain bundle?
362
00:21:45,937 --> 00:21:48,201
Infective neuropathies,
vasculitic neuropathies...
363
00:21:48,273 --> 00:21:50,400
Krabbe's disease,
metachromatic Ieukodystrophy.
364
00:21:50,475 --> 00:21:53,205
HOUSE: AII very bad things.
365
00:21:53,278 --> 00:21:55,906
No way to Iook for any of them
in his condition.
366
00:21:55,981 --> 00:21:57,346
Could be an infection.
367
00:21:57,416 --> 00:21:59,077
I said infection
about eight seconds ago.
368
00:21:59,151 --> 00:22:01,119
You Iisted
some brain infections.
369
00:22:01,186 --> 00:22:05,680
But what if it's just
a regular old infection
festering in the burned skin?
370
00:22:05,757 --> 00:22:08,282
Pus on his arm
isn't causing problems
in the forebrain.
371
00:22:08,360 --> 00:22:11,921
He's on
20 different medications
to manage his pain, his heart,
372
00:22:11,997 --> 00:22:13,658
how often he urinates.
373
00:22:13,732 --> 00:22:16,360
His brain is Iike a waiter
that's got too many...
374
00:22:16,435 --> 00:22:19,165
Hey, hey. I do the metaphors.
375
00:22:21,206 --> 00:22:22,798
The brain is stressed.
376
00:22:22,874 --> 00:22:25,069
An infection elsewhere
could put it over the edge.
377
00:22:25,143 --> 00:22:28,237
So we just wait
for his burns to heal
to see if you're right?
378
00:22:28,313 --> 00:22:31,578
If you're wrong,
he doesn't have
that kind of time.
379
00:22:33,018 --> 00:22:34,576
Dominic Larrey.
380
00:22:35,454 --> 00:22:37,479
He another dead doctor?
381
00:22:37,556 --> 00:22:40,218
He's Napoleon's
Surgeon in Chief.
382
00:22:40,292 --> 00:22:41,850
CIeaned
a Iot of battle wounds.
383
00:22:41,927 --> 00:22:43,326
By amputating Iegs.
384
00:22:43,395 --> 00:22:45,056
And with bugs.
385
00:22:49,835 --> 00:22:53,032
CAMERON: Maggots are implanted
directly into Adam's burns.
386
00:22:53,872 --> 00:22:56,864
Maggots, they eat dead people,
I...
387
00:22:56,942 --> 00:23:00,400
Maggots eat dead flesh.
Only dead flesh.
388
00:23:00,946 --> 00:23:03,881
So they're perfectly suited
to clean wounds.
389
00:23:04,750 --> 00:23:08,117
They also kill the bacteria
that thrive
in injured tissues.
390
00:23:38,183 --> 00:23:39,309
(EXCLAIMING)
391
00:23:45,891 --> 00:23:47,188
Dr. Jekyll, I presume.
392
00:23:47,259 --> 00:23:50,922
They found a half-eaten sheep
in the zoo. The police
wanna ask you a few questions.
393
00:23:50,996 --> 00:23:52,588
I need something
to wash it down.
394
00:23:52,664 --> 00:23:54,723
Coffee? Bad idea.
395
00:23:54,800 --> 00:23:57,894
You're better off with water!
Coffee's closer.
396
00:23:59,871 --> 00:24:01,771
Foolproof plan, by the way.
397
00:24:01,840 --> 00:24:03,637
Either his meds would work,
398
00:24:03,708 --> 00:24:08,338
and you'd be in psychic pain
because Von Evil
is gonna be rich.
399
00:24:09,381 --> 00:24:13,078
Or they wouldn't,
and you get
to be in agony all day.
400
00:24:14,219 --> 00:24:17,188
Perfect Iose-Iose situation.
Very you.
401
00:24:17,255 --> 00:24:20,088
I had to prove...
You've proved nothing.
402
00:24:22,594 --> 00:24:25,461
Right. This isn't a migraine.
403
00:24:26,264 --> 00:24:28,391
Yeah. "Dear New England
Journal of Medicine,
404
00:24:28,467 --> 00:24:31,163
"I took this guy's drug
and still got a headache.
405
00:24:31,236 --> 00:24:34,899
"Thus, scientifically proving
that my arch enemy
is an idiot."
406
00:24:34,973 --> 00:24:36,304
You just wanted the pain.
407
00:24:36,374 --> 00:24:39,866
Meds are supposed
to prevent migraine.
408
00:24:39,945 --> 00:24:41,572
You get distracted by pain.
409
00:24:41,646 --> 00:24:44,410
Leaves Iess room
for the things
you don't wanna think about.
410
00:24:44,483 --> 00:24:47,782
Like the FIyers sucking,
or the price of gas,
411
00:24:48,119 --> 00:24:51,316
or the fact that you pushed
the Iove of your Iife
out of your Iife.
412
00:24:51,389 --> 00:24:54,187
God, I wish the pain
would go away.
413
00:24:54,526 --> 00:24:57,359
Next time you need
to get your mind off her,
stick a needle in your eye.
414
00:24:57,429 --> 00:25:01,229
It's Iess annoying
to the rest of us
when you can still walk.
415
00:25:08,406 --> 00:25:10,135
CAMERON: Did you sleep here?
416
00:25:13,879 --> 00:25:15,039
Lower.
417
00:25:15,981 --> 00:25:17,539
Do you want a pillow?
418
00:25:18,550 --> 00:25:20,211
Not softer, Iower.
419
00:25:21,019 --> 00:25:23,419
Frequency of your voice
is grating.
420
00:25:23,488 --> 00:25:25,217
You should've been better
by now.
421
00:25:25,323 --> 00:25:26,813
I'm super.
422
00:25:27,225 --> 00:25:28,522
Patient?
423
00:25:29,060 --> 00:25:31,551
The maggots
did great for the burn.
424
00:25:31,897 --> 00:25:33,990
But the brain waves
are still all over the map.
425
00:25:34,065 --> 00:25:38,297
Which means your regular
old infection isn't causing
his brain dysfunction.
426
00:25:38,370 --> 00:25:40,235
Which means there's
an underlying condition,
427
00:25:40,305 --> 00:25:43,035
which means
we've gotta get
inside his head.
428
00:25:43,108 --> 00:25:44,905
Do a Iumbar puncture.
429
00:25:44,976 --> 00:25:47,206
We've already established
that we can't get a Iumbar...
430
00:25:47,279 --> 00:25:49,270
C2, C3.
431
00:25:49,347 --> 00:25:51,338
No. No. No way.
432
00:25:51,950 --> 00:25:55,408
I only saw
a cervical tap once,
and that guy got paralyzed.
433
00:25:55,487 --> 00:25:59,924
Ask the parents if they prefer
to have their son
in a wheelchair or dead.
434
00:26:04,396 --> 00:26:07,297
Something's causing his brain
to Iose control.
435
00:26:07,365 --> 00:26:09,265
Eventually it'II shut off.
436
00:26:09,334 --> 00:26:10,858
We need to do
a Iumbar puncture
437
00:26:10,936 --> 00:26:13,803
to get some of the fluid
in his spine
so we can test it.
438
00:26:13,872 --> 00:26:16,033
You need us to sign a consent?
439
00:26:16,107 --> 00:26:17,836
I have to warn you.
440
00:26:17,909 --> 00:26:20,901
There's a serious risk
of paralysis or death.
441
00:26:21,846 --> 00:26:23,643
Are you saying
we shouldn't do this?
442
00:26:24,316 --> 00:26:25,544
You have to do this.
443
00:26:25,617 --> 00:26:27,482
Then why are you telling us
what can go wrong?
444
00:26:27,552 --> 00:26:29,645
I just think
you should know...
Either you're cruel
445
00:26:29,721 --> 00:26:31,621
or this clipboard is a way
for you to cover your ass,
446
00:26:31,690 --> 00:26:33,453
in case you cripple our son.
This isn't his fault.
447
00:26:33,525 --> 00:26:36,585
No, it's not.
It's yours, that's what
you keep telling me.
448
00:26:36,661 --> 00:26:38,288
My son is Iying in there
half-dead,
449
00:26:38,363 --> 00:26:41,594
I am just trying to find a way
to get through this.
450
00:26:41,666 --> 00:26:43,998
I'm sorry.
Yeah, I know.
451
00:26:47,539 --> 00:26:48,733
(MONITOR BEEPING)
452
00:27:03,788 --> 00:27:04,982
Needle.
453
00:27:20,338 --> 00:27:22,829
It's not going in.
Don't force it.
454
00:27:23,274 --> 00:27:24,502
I'm going one space higher.
455
00:27:24,576 --> 00:27:27,773
It's too close
to his brain stem,
it'II herniate.
456
00:27:28,013 --> 00:27:31,141
You're gonna paralyze him.
You're not helping.
457
00:27:31,316 --> 00:27:33,876
His blood pressure's spiking,
stop.
I can get it.
458
00:27:33,952 --> 00:27:36,580
(MONITOR BEEPING RAPIDLY)
He's 180 over 1 20,
he's gonna stroke.
459
00:27:38,256 --> 00:27:40,747
I'm in the space.
Give me the vial.
460
00:27:50,568 --> 00:27:52,433
(MONITOR BEEPING RHYTHMICALLY)
461
00:27:58,276 --> 00:28:00,767
He doesn't have MS
or an infection.
462
00:28:02,681 --> 00:28:05,047
His proteins aren't elevated?
463
00:28:05,116 --> 00:28:07,778
Wrong protein. IgM, not IgG.
464
00:28:08,053 --> 00:28:10,954
EIevation was probably caused
by the bleed.
465
00:28:12,257 --> 00:28:16,284
What if there was tingling
in his extremities
prior to the crash?
466
00:28:16,928 --> 00:28:20,386
How can you still be on MS?
I gotta be on something.
467
00:28:21,066 --> 00:28:24,900
Something's interrupting
his neurons' chitchat,
Iike Iesions.
468
00:28:24,969 --> 00:28:26,732
We can't scan for them.
469
00:28:26,805 --> 00:28:29,968
The only test we can do,
we just did
and it was negative.
470
00:28:30,041 --> 00:28:32,100
He has no tingling,
no numbness.
471
00:28:32,177 --> 00:28:34,645
And you read his history,
parents didn't say
anything about...
472
00:28:34,713 --> 00:28:36,305
What about Adam?
473
00:28:37,682 --> 00:28:41,584
We can't Iook into his brain,
but you want us
to read his mind?
474
00:28:42,520 --> 00:28:43,919
Good point.
475
00:28:49,227 --> 00:28:50,285
(DOOR OPENING)
476
00:28:53,398 --> 00:28:55,958
Yeah, you can finish
the sponge bath in a minute.
477
00:28:56,034 --> 00:28:59,401
They're just
re-doing his dressings.
He's out, he's fine.
478
00:28:59,471 --> 00:29:03,305
I didn't page you
to put him out.
I paged you to wake him up.
479
00:29:03,441 --> 00:29:06,001
Why are these Iights
so damn bright?
480
00:29:06,478 --> 00:29:07,843
Thank you.
481
00:29:07,912 --> 00:29:09,903
Come on,
I need to talk to him.
482
00:29:09,981 --> 00:29:12,677
House, you can't wake up
a burn victim
to play twenty questions.
483
00:29:12,751 --> 00:29:14,719
It's torture.
He won't remember.
484
00:29:14,786 --> 00:29:17,448
He's gonna be
in extraordinary...
God, you're good!
485
00:29:17,522 --> 00:29:19,319
You're putting me to sleep.
486
00:29:19,390 --> 00:29:22,951
I know he's gonna be in pain,
I know you disapprove.
I'm his attending.
487
00:29:23,027 --> 00:29:24,426
Wake him up.
488
00:29:41,679 --> 00:29:43,840
(GASPING)
489
00:29:43,915 --> 00:29:45,405
Oh, my God!
490
00:29:45,483 --> 00:29:47,815
I'm Dr. House.
It hurts!
491
00:29:48,153 --> 00:29:50,121
It's gonna get a Iot worse,
so answer fast.
492
00:29:50,188 --> 00:29:54,887
Before the accident, did you
experience any numbness
or tingling in your fingers?
493
00:29:54,959 --> 00:29:57,450
You got burned, it's healing,
I need an answer.
494
00:29:57,529 --> 00:29:58,723
It really hurts!
495
00:29:58,797 --> 00:30:00,697
Any tingling
in your arms or Iegs?
496
00:30:00,765 --> 00:30:02,460
You gotta do something,
I can't...
497
00:30:02,534 --> 00:30:05,867
Adam, you gotta Iisten to me,
did you feel anything?
498
00:30:05,970 --> 00:30:07,403
(CRYING IN PAIN)
499
00:30:07,472 --> 00:30:12,068
I pissed in my pants
and then I don't remember...
500
00:30:14,479 --> 00:30:17,004
(SCREAMING IN PAIN)
501
00:30:51,382 --> 00:30:54,146
Was he okay?
Get everyone in my office.
502
00:30:55,253 --> 00:30:56,880
Where you going?
503
00:30:57,255 --> 00:31:01,021
Kid's screaming
gave me a headache.
I gotta take an aspirin.
504
00:32:00,118 --> 00:32:03,281
House, you okay?
We've been waiting for you.
505
00:32:07,992 --> 00:32:09,653
I'm hallucinating.
506
00:32:13,031 --> 00:32:16,228
Hallucinations with migraines
are pretty uncommon.
507
00:32:17,001 --> 00:32:20,266
What did you see?
I saw music.
508
00:32:22,206 --> 00:32:24,640
Sensory deception
makes no sense.
509
00:32:28,947 --> 00:32:30,710
You took something.
510
00:32:31,616 --> 00:32:33,982
The kid's
fighting for his Iife.
511
00:33:03,247 --> 00:33:04,509
Hey, you find him?
512
00:33:04,582 --> 00:33:06,675
He was hallucinating
in the Iocker room.
513
00:33:06,751 --> 00:33:08,150
He okay?
514
00:33:08,219 --> 00:33:10,016
He's feeling no pain,
he's high.
515
00:33:10,088 --> 00:33:11,385
Vicodin high?
516
00:33:11,456 --> 00:33:14,050
Past that. He's seeing sounds.
517
00:33:14,325 --> 00:33:15,883
Took something.
518
00:33:18,763 --> 00:33:21,425
Why is it so dark in here?
It's a beautiful day outside.
519
00:33:21,499 --> 00:33:24,127
Open the shades,
Iet the sun shine in.
520
00:33:24,202 --> 00:33:25,760
It's nighttime.
521
00:33:27,605 --> 00:33:30,574
It's still Tuesday, right?
You Iook better.
522
00:33:30,942 --> 00:33:33,570
I took something.
Mind if I ask what?
523
00:33:34,979 --> 00:33:37,243
Little of this,
Iittle of that.
524
00:33:37,315 --> 00:33:39,306
I know
what's wrong with our patient.
525
00:33:39,384 --> 00:33:40,908
He's depressed.
526
00:33:40,985 --> 00:33:42,680
He told you that
when you woke him up?
Nope.
527
00:33:42,754 --> 00:33:44,517
He told me he pissed his pants
and blacked out.
528
00:33:44,589 --> 00:33:47,786
That's not diagnostic of
depression. Lack of appetite,
isolating yourself.
529
00:33:47,859 --> 00:33:50,987
Uncontrollable urination
and blacking out
are good predictors of what?
530
00:33:51,062 --> 00:33:52,120
Seizure.
531
00:33:52,196 --> 00:33:54,630
Which means the seizure he had
when you tested his heart
532
00:33:54,699 --> 00:33:56,667
was at Ieast
his second seizure.
So what?
533
00:33:56,734 --> 00:34:01,137
Depression and seizures
aren't correlated.
No, but you know what is?
534
00:34:01,205 --> 00:34:03,799
Depression
and anti-depression medicine.
535
00:34:03,875 --> 00:34:05,433
Tox screen was clean.
536
00:34:05,510 --> 00:34:07,705
Yeah, but you know
how much crap
he's got in his system
537
00:34:07,779 --> 00:34:08,939
for dealing with those burns.
538
00:34:09,013 --> 00:34:11,982
The guy could have
the Spanish Armada floating
through his bloodstream
539
00:34:12,050 --> 00:34:14,644
and we wouldn't know about it,
till they started
firing cannons.
540
00:34:14,719 --> 00:34:18,314
Antidepressants have been
known to cause seizures
in kids, but not orgasms.
541
00:34:18,389 --> 00:34:22,553
This is a brain in trouble.
This is a brain
with too much serotonin.
542
00:34:22,627 --> 00:34:26,427
Serotonin affects mood,
appetite, it doesn't cause
the brain to shut down.
543
00:34:26,497 --> 00:34:29,625
Antidepressants fake brains
into thinking
they have more serotonin
544
00:34:29,700 --> 00:34:31,031
than they actually do.
545
00:34:31,102 --> 00:34:34,833
Every ten million or so cases
sets off a chain reaction.
546
00:34:34,906 --> 00:34:37,534
Produces too much,
enough to fry itself.
547
00:34:37,608 --> 00:34:39,974
If Adam has Serotonin Storm,
it's deadly.
548
00:34:40,044 --> 00:34:42,274
But treatable. Cyproheptadine.
549
00:34:42,346 --> 00:34:43,904
Unless he doesn't have
Serotonin Storm.
550
00:34:43,981 --> 00:34:46,609
He could just as easily have
too much dopamine
as serotonin,
551
00:34:46,684 --> 00:34:50,245
but if it's dopamine,
the cyproheptadine
will kill him.
552
00:34:50,321 --> 00:34:53,290
Where are you going?
Gonna talk to the kid again,
he seems nice.
553
00:34:53,357 --> 00:34:54,722
You can't.
554
00:34:55,126 --> 00:34:56,616
Why? Did he say
he doesn't Iike me?
555
00:34:56,694 --> 00:34:59,822
Anesthesiologist
told the parents what you did.
556
00:34:59,897 --> 00:35:01,888
Everyone's a tattletale.
557
00:35:08,339 --> 00:35:10,204
Is your son depressed?
558
00:35:11,776 --> 00:35:14,244
No. Who are you?
I'm Dr. House.
559
00:35:14,312 --> 00:35:15,574
Oh, you're the idiot
who thought...
560
00:35:15,646 --> 00:35:17,443
I heard him screaming
all the way down the hallway.
561
00:35:17,515 --> 00:35:20,382
If I didn't wake him up,
I wouldn't have Iearned
what caused the crash.
562
00:35:20,451 --> 00:35:22,078
He had a seizure.
563
00:35:25,456 --> 00:35:27,287
This wasn't my fault?
564
00:35:28,326 --> 00:35:31,489
Well, if he hadn't
had the brain problem,
he wouldn't have the burns.
565
00:35:31,562 --> 00:35:33,655
On the other hand,
if you hadn't put him
on the ATV,
566
00:35:33,731 --> 00:35:34,959
he also
wouldn't have the burns.
567
00:35:35,032 --> 00:35:37,193
You can debate
your personal responsibility
after I Ieave.
568
00:35:37,268 --> 00:35:38,758
I need to wake him up again.
569
00:35:38,836 --> 00:35:40,667
I need to know if
he's taking antidepressants.
570
00:35:40,738 --> 00:35:42,000
He's not.
571
00:35:42,840 --> 00:35:46,571
He's the happiest kid I know.
But you don't know, do you?
572
00:35:48,746 --> 00:35:50,145
He's my son.
573
00:35:50,715 --> 00:35:52,376
That's sort of my point.
574
00:35:52,450 --> 00:35:55,851
At 16,
they'II tell anyone anything,
except their parents.
575
00:35:55,920 --> 00:35:57,615
Adam talks to us
about everything.
576
00:35:57,688 --> 00:35:59,747
Yeah, I know
about the pot and the cocaine.
577
00:35:59,824 --> 00:36:01,689
There was never... Cocaine.
What...
578
00:36:01,759 --> 00:36:04,853
Are you sure?
Are you having him followed?
579
00:36:04,929 --> 00:36:07,523
He told us
when he got drunk at a party.
580
00:36:07,598 --> 00:36:09,429
He told us
when he started having sex.
581
00:36:09,500 --> 00:36:11,195
At 16? Way to go.
582
00:36:11,269 --> 00:36:12,998
He told us
when he cheated
on a math test.
583
00:36:13,070 --> 00:36:15,300
He told us
when his girlfriend
cheated on him.
584
00:36:15,373 --> 00:36:18,342
He doesn't hide
anything from us.
But if he was depressed?
585
00:36:18,409 --> 00:36:19,899
He'd tell us.
586
00:36:20,111 --> 00:36:23,046
We don't judge,
he's not depressed,
we're sure.
587
00:36:23,114 --> 00:36:25,241
"Bet his Iife on it" sure?
588
00:36:26,918 --> 00:36:28,715
Just hypothetically.
589
00:36:30,288 --> 00:36:31,380
Yeah.
590
00:36:34,926 --> 00:36:36,018
Okay.
591
00:36:38,863 --> 00:36:40,296
Kid's happy.
592
00:36:41,232 --> 00:36:43,257
Happy, happy, happy.
593
00:36:43,568 --> 00:36:46,969
Then we're back
to where we started.
Seizure disorders.
594
00:36:47,038 --> 00:36:49,939
Seizure disorders
aren't causing orgasms.
595
00:36:50,007 --> 00:36:51,634
Vascular malformations?
596
00:36:51,709 --> 00:36:53,768
Would've seen it
on the sonogram.
597
00:36:53,844 --> 00:36:55,903
Hepatic encephalopathy?
598
00:36:55,980 --> 00:36:58,278
Liver enzyme tests
were normal.
599
00:37:04,188 --> 00:37:06,656
Where are you going?
Take a Ieak.
600
00:37:14,732 --> 00:37:15,858
What are you doing?
601
00:37:15,933 --> 00:37:17,924
You can't come in here,
you're not sterile.
602
00:37:18,002 --> 00:37:19,401
Don't touch our son,
we told you...
603
00:37:19,470 --> 00:37:22,064
Seriously,
millions of bacteria,
microbes on you.
604
00:37:22,139 --> 00:37:25,074
He'II die of sepsis.
If you go in there...
605
00:37:28,913 --> 00:37:30,471
I think
he's gonna wake him up again.
606
00:37:30,548 --> 00:37:32,106
I know he is.
607
00:37:33,884 --> 00:37:35,681
House, you can't do this.
608
00:37:35,753 --> 00:37:39,883
Oh, if I had a nickel
for every time
I've heard that. Relax.
609
00:37:39,957 --> 00:37:43,586
Are they gonna sue us?
If I'm right, I save his Iife.
610
00:37:43,661 --> 00:37:46,630
If I'm wrong,
he's dead no matter what I do.
611
00:37:46,964 --> 00:37:49,933
Either way, how much
have I really hurt them?
612
00:37:50,001 --> 00:37:51,263
Leave him alone!
613
00:37:51,335 --> 00:37:53,735
You're not sterile.
Do you wanna kill the kid?
614
00:37:53,804 --> 00:37:55,772
Give me the syringe.
No pain, no gain.
615
00:37:55,840 --> 00:37:57,831
Hey, you gotta stop this.
616
00:38:02,013 --> 00:38:03,480
They're right.
617
00:38:04,348 --> 00:38:07,078
He's not depressed.
FOREMAN: Yeah, sure.
618
00:38:07,151 --> 00:38:09,779
I'm not Ietting you go
till you give me that syringe.
619
00:38:09,854 --> 00:38:11,845
What's that on his wrist?
620
00:38:12,923 --> 00:38:14,151
A burn.
621
00:38:14,225 --> 00:38:16,557
Why on his wrist?
Why not on his wrist?
622
00:38:16,627 --> 00:38:20,529
His back, his torso,
everything's a mess.
His forearms are clean.
623
00:38:20,598 --> 00:38:22,793
Except right there.
So what?
624
00:38:24,235 --> 00:38:25,600
It's a perfect circle.
625
00:38:25,670 --> 00:38:29,970
So a drop of burning gasoline
fell on his wrist,
a screw from the ATV.
626
00:38:30,708 --> 00:38:31,868
Maybe.
627
00:38:41,952 --> 00:38:44,853
Why are you torturing him?
Does your son smoke?
628
00:38:46,157 --> 00:38:47,624
I'd kill him.
629
00:38:49,627 --> 00:38:53,996
So, he can talk to you
about sex, crack,
anything except cigarettes.
630
00:38:55,232 --> 00:38:57,826
He has a cigarette burn
on his wrist.
631
00:38:58,436 --> 00:39:01,633
AIso a fading nicotine stain
between two fingers.
632
00:39:02,440 --> 00:39:05,637
Bad news,
your son has a filthy,
unhealthy habit.
633
00:39:05,710 --> 00:39:08,076
Good news,
he's trying to quit.
634
00:39:08,145 --> 00:39:10,272
Bad news,
the quitting's killing him.
635
00:39:10,348 --> 00:39:13,146
Good news,
I can cure him. Bad news...
636
00:39:14,618 --> 00:39:16,848
Nope, that's the end of it.
637
00:39:16,921 --> 00:39:18,912
Quitting smoking can kill?
638
00:39:18,989 --> 00:39:21,219
No-smoke meds
are antidepressants.
639
00:39:21,292 --> 00:39:23,351
The crappy ones
you get over the Internet
640
00:39:23,427 --> 00:39:26,225
are Ioaded
with whatever antidepressants
they can get cheap.
641
00:39:26,297 --> 00:39:30,597
And since Mommy and Daddy
obviously didn't take him
to a pediatrician...
642
00:39:32,970 --> 00:39:35,939
Sorry, I was wrong
about him being depressed.
643
00:39:36,540 --> 00:39:37,871
Treat him.
644
00:39:54,959 --> 00:39:55,983
(DOOR OPENING)
645
00:39:56,060 --> 00:39:57,152
CUDDY: Hey!
646
00:39:58,262 --> 00:40:00,423
Did you drop acid?
647
00:40:02,133 --> 00:40:05,000
Why would I do that?
To annoy me.
648
00:40:05,136 --> 00:40:07,502
Or maybe because
you're miserable,
649
00:40:07,571 --> 00:40:10,870
or because
you want to self-destruct.
650
00:40:11,208 --> 00:40:12,505
Pick one.
651
00:40:12,977 --> 00:40:16,936
How about because LSD
acts on serotonin receptors
in the brain,
652
00:40:17,014 --> 00:40:19,812
which can stop
a migraine in its tracks.
653
00:40:20,351 --> 00:40:22,819
I'm just saying
that's also a possibility.
654
00:40:22,887 --> 00:40:26,323
How did you know about it?
Cameron is worried about you.
655
00:40:26,390 --> 00:40:30,292
I told her that LSD Iasts
up to 1 2 hours, if you were
functional, she must be wrong.
656
00:40:30,361 --> 00:40:33,194
Either that or I also took
a whole bunch
of antidepressants,
657
00:40:33,264 --> 00:40:35,357
which short-circuited the LSD.
658
00:40:35,433 --> 00:40:37,264
I'm just saying
that would also explain it.
659
00:40:37,334 --> 00:40:39,632
Thank you for ruining
my clinical trials.
660
00:40:39,703 --> 00:40:41,694
Pharmaceutical company's
shutting me down.
661
00:40:41,772 --> 00:40:44,002
You're kidding. Really?
How could that surprise you?
662
00:40:44,074 --> 00:40:45,268
You sent them an email
663
00:40:45,342 --> 00:40:47,902
complaining about my math,
telling them about your stunt.
664
00:40:47,978 --> 00:40:50,173
I didn't know
people actually read emails.
665
00:40:50,247 --> 00:40:52,977
Delete button's
so conveniently Iocated.
So what's next?
666
00:40:53,083 --> 00:40:54,607
You gonna follow me
my whole Iife?
667
00:40:54,685 --> 00:40:56,482
Torture me?
Why would I do that?
668
00:40:56,554 --> 00:41:00,650
You waited 20 years
to do this. What's next?
Break up my marriage?
669
00:41:01,492 --> 00:41:04,757
No. We're even.
Right.
670
00:41:06,864 --> 00:41:09,059
Oh, thanks for setting me up.
671
00:41:12,770 --> 00:41:16,137
Eye for an eye,
LSD and antidepressants.
672
00:41:16,941 --> 00:41:18,772
Everything in balance.
673
00:41:18,843 --> 00:41:21,903
Buddhists call it Karma.
Christians call it
the Golden Rule.
674
00:41:21,979 --> 00:41:23,571
Jews call it...
675
00:41:25,616 --> 00:41:28,881
I don't know,
Rabbi Hillel
said something poignant.
676
00:41:30,254 --> 00:41:32,688
Universe
always settles the score.
677
00:41:33,524 --> 00:41:35,992
Does it?
No.
678
00:41:37,895 --> 00:41:39,419
But it should.
679
00:41:47,137 --> 00:41:51,130
Do you think you'II ever
be able to Iook at him
and not blame me?
680
00:41:52,042 --> 00:41:55,068
Yeah. Will you?
681
00:42:24,642 --> 00:42:25,802
(KNOCKING AT DOOR)
682
00:42:46,864 --> 00:42:48,195
PAULA: I'm Paula.
683
00:42:48,465 --> 00:42:51,059
Hey, Paula.
How you doing?
684
00:42:52,603 --> 00:42:55,629
You work over at the college,
or are you full-time
over at the...
685
00:42:55,706 --> 00:42:57,970
I'm Iooking for a distraction.
686
00:42:58,742 --> 00:43:01,575
You don't need to talk
to do that, do you?
53923
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