Original subtitles

good afternoon to all of you thank you

for joining me today for this important

topic of prostate health solutions

backed by research today the topic of

prostate health and prostate cancer it's

a huge topic and if I would go in detail

into what I want to touch on today it

will take me hours so I will pick a few

important point share with you some

important updates on the research that

I've been involved in for almost 25

years and now some very important

studies that just came out you may

clinical trials but I will try to use

very simple conditions that in on

prostate health such as BP age and

prostate cancer a little bit [ __ ] light

about the about there about the larger

context of positive so we can start with

talking about BPH benign prostatic

hypertrophy so we discuss contributing

factors integrative solution and also a

very important paper that was just

published that was just published and

they share share the results and then we

also talk about prostate cancer a little

bit about the facts integrative options

and we'll discuss they're very exciting

result of modified sit respected a

multicenter clinical trial in

biochemical relapse that where i

presented the results in a scott gu in

San Francisco in February so I will get

going

so BPH is a very common condition it's

really a physiological condition it's

something that happens over time in age

for men and it's a basically a swelling

of the prostate that puts pressure on

there on the urethra and as the results

causes different symptoms urinary

symptoms pain and sexual dysfunction

sometimes and the question is what makes

it to come sooner rather than later and

how can we prevent it and treat it so

with

actually we'll be developing these

issues from a point of view of

understanding the prostate is an

independent organ which is really how

it's done in Western medicine to really

understanding what else in the body

effects the prostate if we can

understand the health of a certain organ

from more of a global holistic approach

this model is what makes the difference

between an okay treatment and a gray

treatment

so again BPH as I mentioned is a very

common condition you can see about 50

percent between age 51 and 60 and then

90 percent when we are older than 80 so

as we age the prostate grows and swells

and I won't go into all the mechanisms

of action mainly because of limitation

of time you can understand there are so

many people who are millions of mean

intensive terms of million of mental

health issues so when the when the vp8

pressurizes the urethra it creates what

we call lots lower urinary tract

symptoms that include the urinary

frequency and urgency frequency needing

to urinate many time urgency we can't

hold the urine nocturia getting up

frequently at night to urinate the

nocturia for example is the factor that

will affect our quality of life because

we are not sleeping well in the same

time stress anxiety emotional issues

other imbalances that affect our sleep

will cause us to already get up to pee

because when we awake we are more

quickly aware of the need to pee even if

it's a little bit but an example for

example about the connection between the

heart which relates to sleep in Chinese

medicine and the bladder and interesting

there are they actually coupled there is

there is a connection building between

them and there are certain herbs an

acupuncture point let's tie into this

relationship some of the Chinese wisdom

there is a symptom of hesitancy where

it's how to start peeing and it's

interrupted in the stream is weak and

incomplete bladder emptying which can be

initially to lead to

secondary infections straining decreased

force extreme dribbling and the find

operations of the points on the wrist

line prostatic problem that can affect

ejaculation causing pain in the sexual

dysfunction but these are symptoms that

many many men experience in one way or

another and just for you when you have

it you want to pay attention what makes

a difference

didn't I need a good night's sleep make

a difference did what you eat in the

last few days make a difference did if

you exercise did it make a difference

and start seeing what affects you one

thing is know what effect somebody

statistically but really medicine is a

medicine in modern medicine as a

medicine of statistics real medicine

live medicine is medicine of N equals

one is what works for each of us that

matters for each of us so if we look at

the BP agent we see what contribute to

BPH and we can go from genetic

predisposition to hormonal imbalances to

diet and lifestyle to toxicity to

metabolic dysfunction to aging and the

king of everything chronic inflammation

when we look at this we can really very

quickly see and understand that the

prostate is really a reflection of

multiple health system that can affect

so many other organs and it is very very

interesting because classically BPH is

being treated sometime by your primary

care but offered by a urologist which is

very organ and system specific but we

can see it especially for prostate it's

unusual how many other systems can

affect the prostate so I wanna I wanna a

little bit expand on it in the context

of BPH but please take these comments

into prostate cancer which is much more

critical so the genetic predisposition

is one thing we can determine these days

and I'll touch it I'll touch I'll go

back to it in a moment but I want talk

about hormonal imbalances and no moral

imbalances accrued to powers it includes

the whole Oh

kornel deficiencies or exercise when you

test your hormones are too high or too

low but also how are you breaking down

your hormones what is happening to your

hormones when you break them down it's

very important and this is the place

where genetic predisposition can affect

if you have certain mutation certain

snip pair changes MTHFR etc etc then you

will get hormones are being processed

for example in the liver broken up to

less healthy hormones and in men while

we focus on testosterone in DHT we have

to remember that many to age 55 has the

same level of estrogen sometimes higher

than women and if we have an inability

to break our estrogens properly in the

liver and we have very high f4h

is to estradiol or high ratio of of 16

to 2 estradiol and these are unhealthy

ratios this will increase our chances

for prostrate heal health issues and

specifically for prostate cancer but

also will make the cancer more

aggressive so when we look at these it's

just an example but when we visit picked

hormonal imbalances we're aware that the

process is stimulated and being enlarged

by testosterone but especially by

dehydrogenase customer and when we look

at the production of behaviour

testosterone it's very interesting it

can be produced in the testes on a local

level it can be converted in the

prostate it's produced it's significant

amount by the adrenals it's incense and

production of the liver the Sun

production is the brain and there are

some production in fatty tissues

depending on different enzymes a 5 alpha

reductase or aroma change how we are

shifting the testosterone so you can see

our multiple system are affecting the

prostate if we look at atomic Li if I go

back for a moment and I look

anatomically at the prostate imagine

that a bath is a prostate you got your

whole body right this is like the bottom

photos which means that everything that

we have in our body funnels down into

this area we can often see it in the

different cancer that we get and I'll

touch on it toxicity is very important

for the prostate and we'll talk about it

more in prostate cancer metabolic

dysfunction I touched a little bit in

hormone but I will touch later more in

aging especially for the pH so the goals

with me pH is first of all to relieve

the symptoms of BPH to reduce the lower

urinary tract symptoms to improve

quality of life to reduce the prostate

size and if needed different surgical

intervention which are we kind becoming

more and more refined but offer have to

be repeated so if we look at this as the

general level of the prostate hill then

the goal initially in prostate health is

to address BPH reduce prostate size of

course there's the whole area of

prostatitis that can clearly contribute

to prostate cancer more than BPH but we

decided not to touch on it today because

of a issue of time and then of course

how do we prevent the development of

positivism and when we look at prostate

cancer and I'll talk about it in a

separate ways so we also want to

understand the prostate cancer is really

a wide array of serious conditions where

it can be very physiological or can be

very aggressive when we look at the

prevention of development of prostate

cancer we want to look at restoring your

hormonal balance which is what I call

hormonal modulation

differend and hormonal replacement we

want to look at improved metabolic

health very specific metabolic syndrome

adrenal support and is key ones balance

between the adrenaline the thyroid and

the metabolic from the point of view of

glucose metabolism is critical because

elevated igf-1 insulin

because elevated insulin because of

obesity all of these have an important

effect of the prostate and um cancers in

general of the pelvis in both men and

women one look at tides the Demont

inflammatory gluten-free low glycemic

index high protein not fried food and no

soft wings etc you want to address what

we ate nutrient deficiencies establish

regular exercise routine is very

important there is no better medicine

than exercise I mean it's remarkable

when we look at the change in survival

after initial cancer treatment between

people who walk regularly and on it's

50% reduction it's unreal it's a best

medicine to ever be discovered and

totally free and within within it we

want to look at the detoxification of

heavy metals and environmental toxins

which will touch on a little bit later

and stress reduction now it's

interesting we are showing this on the

level of prevention of the development

of prostate cancer but all of these will

also contribute to be pre agent to

prostatitis in the package so we can

have targeted natural compound the

nutrients to support this process and of

course we have medication silica and

other interventions more in this in this

context today we're gonna focus on the

pH and of course similar of course for

prostate cancer so when we look at the

classical categories for treating the pH

often there is spasm of the of the

muscle of the of the bottom of the

bladder which hasn't let the urine flow

well when the upper part is too relaxed

it doesn't push the urine out and for

this we use alpha blockers there are

different ones

I mean floor mats Hydra dura I mean I've

been around for many years

and they can help relatively quickly the

problem that they have multiple side

effects because you can control the

block the alpha blocker they can reduce

your blood pressure cause dizziness

abnormal ejaculation erectile

dysfunction addict or so static

hypotension that they just mentioned and

fatigue and also study guide potential

can be very significant in the alpha

blockers because the Alpha system is is

the sympathetic system that comes it is

our emergency system our response system

if it's blocked and we get up and now we

leave the blood the pressure to go up

and sustain our circulation that has to

fight gravity now if you don't get a

response you can fade you can feel

light-headed Knesset's it another

category that is very commonly used is

the 5 alpha reductase inhibitors

inhibitors so these are important drug

is that inhibits the movement from

testosterone to dihydrotestosterone they

have an effect on B pH of course and

they also have an important effect in

prostate cancer for people who use

combined hormonal therapy the prostate

cancer has been a movement since the

early 90s and now it's been getting more

and more established you know you use a

in LH our age agonist that stops the

excretion of testosterone like you

pro-lite in an example and then you use

a product that blocks the effect on

there in the confusion on the prostate

like gas or eggs

standee and then i use something that

specifically block the conversion from

testosterone to the hyper distrust the

problem is that when you block it you

have a movement to the other direction

with increased level of estrogens and so

there is some erectile dysfunction not

the same like when you block the

expression of testosterone but a

significant percentage of normal

ejaculation decreased libido depression

anxiety breast enlargement can be severe

for some people and it may increase the

risk of

that cancer especially the work was done

with Bosco so there are some classical

herbs for prostate health that you see

many formulas saw palmetto or by Geum a

pumpkin seed stinging nettle and these

are herbs that have an anti-inflammatory

or monel modulation effects on the

prostate and they will have a benefit in

within a benign Empress in the pH and

also have some benefit in prostitutes

there's some studies showing quercetin

is a remarkable ingredient it's much

bigger than the prostate quercetin is an

anti-inflammatory effect has a

detoxification effect as the regulatory

effects on simple quercetin will prevent

resistance to chemotherapy in different

cancers breast cancer adjacent

quercetin will allow a circulating tumor

cells to become less aggressive

worsening is a very important compound

in the prostate specifically it has an

effect on prostatitis specifically in

someone BPH so if we look at if we look

at how how to really address prostate

health we have all this multiple

category that I showed you a little bit

earlier it has all the categories of

hormonal modulation to addressing

toxicity addressing immunity unless in

circulation addressing inflammation so

this is really the approach that needs

to be taken care of when you go to a

holistic doctor who sees the prostate

bigger than the prostate but there is

also a way to reflect this in

formulation for example in this specific

formula that has multiple published

papers a that's the idea using 33

different ingredients to address the

different categories now the

presentation not specifically on this

formula but if you look at such a

formula we see how the different organs

which address an issue our address space

by

by different ingredients so the study of

the prostate health supplements if it

was a retrospective study on 65 men

evaluating their change in lower urinary

tract symptoms 65 men 20 with prostate

cancer 13 with pph to anyone who is

multiple diagnosis meaning vpa prostate

cancer

Titus maybe and 11 with no formal

diagnosis but this specific formula for

most serious conditions you go up to 12

capsules a day

but interesting some of the subjects to

address just during urinary issues used

only two capsules a day was unusual

literally two twice a day and still we

gained benefits and at least two months

was the inclusion criteria but most of

the people on this study had been using

this for years so we are seeing a

long-term benefit it's something

important when you design a formula in a

synergistic way you don't lose the

benefits over time compared to a drug

where you often get tolerance so that's

another very unique feature of natural

holistic approach that is important to

recognize so when we looked at the

improvement in symptoms based on

questionnaires giving to the 65 subject

we saw sixty point seven percent

improving staining is to understand

about 44 percent in intermittency

similar effect in with improvement of

extreme incomplete emptying and then

significant improvement in or urgency

knocked or and frequency and although

the percentage was four for urgency may

look lower compared to two what the

placebo or does it actually was very

significant so we understand that benign

prostatic health is universal is a

significant impact on quality of life

but it does not sweat in your life it

does not lead directly to prostate

cancer but we really have to be

concerned about and be aware of his

prostate cancer

and prostate cancer is the second most

common cancer in men and the other than

skin cancer is the most common cancer in

the US and about one in seven men will

be diagnosed with cancer and the

estimated number of many ways prostate

cancer is now close to three million

people two million seven hundred

thousand if caught early like many other

cancers it is one of the most visible

malignancies and it's a qualified

statement though certain prostate

cancers that are so aggressive that

they're going to show up regardless of

what you've got a reoccurring goddess of

what we do but we don't have time to

avoid this greater detail we can touch

it

what's really important is they you know

underst why we understand it's the

second leading cause of cancer deaths in

American men behind lung cancer and we

want to look at its average age so the

average is it's 66 percent which still

seem like it's an disease of all people

it comes know you should say all people

but not they young people but we have to

understand we look at this data we

really have to understand it's what's

happening so our our survival that goes

out many more people leads to the 80s

into the 90s and just like BPH many men

as they age and get older into the 80s

90s can come up with what I often call

physiological prostate cancer and

low-grade Gleason 6 prostate cancer

Gleason is the reflection of the

aggressiveness of the prostate cancer

with the lowest one being diagnosed as

cancer is six in a very aggressive one

is 10 it relates to genetic mutation and

aggressiveness of the consumer so if we

can look at 66 is a it's an average and

we have two men who got prostate cancer

at age 80 they will actually balance

somebody's age 38 that got prostate

cancer and we see now men in their

thirties coming

with prostate cancer very often more

aggressive posture kids why the prostate

cancer more aggressive one because the

person metabolism physiology activity is

faster

everything is moving faster and second

because more extreme factors were needed

to produce prostate cancer over a

shorter period of time we also have to

remember we look at these statistics

that now is PSA very commonly done

compared to 34 years ago we are finding

this benign non aggressive prostate

cancer at later age we would have not

found in the past people when just died

was posted cancer that nobody knew about

and this also skews the age to a higher

age so the take-home takeaway point is

don't disregard the possibility of

having prostate cancer at a young age

the other thing is a team dedicated

slight when I want to end is the whole

story of PSA so for me personally always

PSA is great value PSA testing is great

value when done appropriately going

where it's done one in the contest of

how big is the prostate because if the

PSA is high with a very large prostate

it's less worrisome because we can

explain the PSA so if you have somebody

were the digital rectal exam on

ultrasound show the small and 30ml

prostate 20 ml even 25 you will really

expect these people to have under to PSA

and the camera is 4.5 it's a concern but

if somebody is a huge prostate which is

80 ml and the PSA is 5.6 or 6 it can all

expert be explained by the normal

excretion from the tissue the other part

is a type II assay with urinary symptoms

is less worrisome than high PSA without

M C because again we can explain it so

in my perspective I use PSA to

understand the patient and then I look

at many other metabolites and many other

factors both in the one-on-one care and

both of us formulate products

so what is the integrative approach to

to to prostate cancer which I touched

about a little bit before so we can see

the approach to prostate cancer is

multi-pronged I want to emphasize it

from a from a conventional medicine

point of view there's a lot of exciting

new treatment I just did a chance to

present an Oscar

gee you asked genitourinary annual

conference in San Francisco in February

our study modified it was picked in

which I will share in a moment and there

were some very big news about some new

drug extended for long term prostate

cancer patient or failing hormonal

therapy and this is good news but the

drug that you are going to get is not

driven by who you are but what but by

which mechanisms of action are driving

your treatment it's sometime remarkable

for example if we look at the field of

immunotherapy like PDL 1 inhibitor of

CTL foreign immatures you check for the

receptors for these molecules and I

won't go into the detail of what they

are but even if make a large Institute's

you know the largest Cancer Institute

they will not try to understand the

immune system in a deeper more

comprehensive way because it's not

needed it's not indicated to give the

drug so this is as we made progress

these drugs are important but we really

want to understand what is driving the

condition because for each of us there

are different things so as I often say

conventional treatments for cancer can

get very good results so let's say we

look at at the breast cancer we do not

the topic or often a chemotherapy is a

very late stage in prostate cancer but a

certain treatment that is a 70% response

it doesn't matter

which doctor you go to you're gonna get

the same treatment with 70% it will take

an integrative doctor a lot of work

creativity and unique know how to take

up from let's say 70 to 72 or 75 of 80

or 82 in order to take it up to 80 when

you reduced the risk you improve the

response the survival of the 30% by 1/3

but what's so important that when we do

it we have a very important side effect

we feel better emotionally we feel

better physically we are more productive

we are happier there's part of an

integrative approach I want to emphasize

this because you can always integrate it

into your care so looking at these

factors now you want to look at some

important issues so immune enhancement

is very important it's not as important

in hormonal driven tumors but we do

whenever good in your response and we

want to make sure that the immune

response can get to the cancer cell what

do I mean we're gonna have a strong

immune response and let's say we

increase certainly a compound that can

kill cancer like tumor necrosis

factor-alpha TNF alpha if the tumor is

shielding itself from the system its

coating itself with the system the the

compound will not be able to get to the

cancer and if the cancer in children and

creates a micro environment with its own

metabolic environment its own PA

its own growth factor it becomes an

independent entity within our body and

our immune system doesn't live the way

to address it so immune enhancement is

not such a simple concept and we now see

it we see it for example with

immunotherapies that can give benefits

but the benefits are related also to

side-effects to inflammatory side

effects because because there is no

change in the local tissues if you fight

it and there's already inflammation will

become worse the other part which is

very important in prostate it's hormonal

and metabolic modulation and modulation

is beyond just hormonal therapy we have

to understand the patient

or Monali before you take your first

treatment I always say this is the map

this is a baseline and if we don't take

a good picture we can never come back

so for numbering the clinic I will run a

lot of lunches no of course this Joss

Stone and the in DHT and total esposende

in the different estrogen and igf-1 and

prolactin and the hemoglobin a1c and I

want to see the relationship between

them I will look at different a

different compound that can affect them

and then I will look at metabolic

factors thyroid function adrenal

function cortisol and see how they

relate to each other in the specific

person why is this so important if

you're gonna give the same drug because

if you take a good sniff shot of what

happened before you start treating you

are being shown the road that cut you

into this situation and then when you

want to backtrack make the treatment

more effective or continue holistic

approaches after formal therapy that's

so important to really understand very I

can't emphasize this enough and they're

not done often enough

I regret because we live because of cost

insurance driven medicine so then when

we look at this when you look at direct

cytotoxicity how can we directly attack

the cancer if it's botanicals if it's

other compounds etcetera so driving

cytotoxicity INRI differentiation are

closely related one of them tries to

kill and one of them tries to make the

sale normal so for example certain

things like vitamin D vitamin a sodium

vanilla Beauty rate or no key on which

is key helped in we differentiation

modified citrus pectin also does it

because the mother is an expression of

collecting 3 the more that cancer is in

the female of cells in the cancer stem

cells become more aggressive

exactly key mechanism we want to balance

addressing both of them

either in the same time or if you're

getting a certain treatment within the

treatment cycle for example my a my

clinic I adjust the supplements based

someone is doing in a dynamic way where

it changes over let's say somebody gets

a certain treatment every three weeks

the supplements will change again I try

to reflect this as much as I came in in

a sleeper supplement that's why you need

so many Gideon's we also want to

recognize detoxification heavy-metal

environmental toxins have direct effect

on the prostate why because heavy metals

are heavy the process is the lowest part

in our torso so naturally heavy metal

will sink into this area if we look at

cancer in men in children we can get of

course different bone marrow cancers you

know in central nervous system cancer

that relate a little bit to the same

system Chinese medicine and then we can

get osteosarcoma cancer of the bones

below the pelvis beautifully and then

the first cancer we get is we get to

stick with our cancer and afterwards

we'll start moving upward and we get

frost occurs similary minutes in their

cancers so we can see a little sis it is

sinking into the bathroom and that's

where dietary changes detoxification

herb removal of heavy metals can be very

important in the same category with

conditions with with related importance

is addressing circulation in hyper

viscosity if the blood is too thick if

the circulation is not normal we'll get

tissue which is his hype oxidation

doesn't have enough oxygen it becomes

more synthetic more lactic acid lactic

acid increases hypoxia and using factors

which again shuts down the mitochondria

because about economy our consumption

there's no oxygen that can produce

energy and now it's a vicious cycle and

for example a drug like metformin is

very important in addressing it and

more effective is on opioid doctor we

specifically addressed the metabolic

component that will affect we

differentiation from the point of view

of re-establishing normal mitochondrial

function turning an abnormal cell into a

normal cell but also because there is

not a see more cyclic a and P being

produced there is more normal function

of the cell a little example of one

compound like Pinocchio that can work in

so many places and is this very unique

quality to to recognize cancer cell in

three different and then prevention of

metastasis and your Genesis where

modified is respecting is the leading

compound with soly data in vitro in vivo

and multiple human clinical trials so

let's talk a little bit about galatians

being motivated respecting that's a

field that we've been involved with for

almost almost 25 years for 23 years now

and i'll share with you just some

highlights because there's too much to

share a few minutes a modified c2

expecting binds and blocks the adverse

effect of collectively collecting three

is a protein that binds carbohydrate so

it binds oxidized glycolipids like a

proteins and when it binded to create a

lattice formation covering the cover

that covers the tumor cells and allow

the tumors to height they cover that

allows that shuts down the response of

the immune cells and there's a lot of

other effects of inflammation in

fibrosis but specifically in cancer

exposure log electives we will promote

as you can see in the slide aggregation

of cancer cells tumor growth invasion

and migration of the tumor immunization

explained greatly how by surrounding

they say as a tumor cell angiogenesis

growth of new blood vessel because PGs

father endothelial growth factor

attaches to the galatians we

vision of apoptosis cell cannot just

diet keeps living emitters metastasis

the initial work in modifies it

respecting most specifically metastasis

newspapers published in the leading

journals so ladies we really is a master

conductor of the tumor microenvironment

it's similar to refer to proliferation

in inhibit apoptosis intracellular

effects it stimulate migration promotes

invasion metastasis formation cell to

cell interaction and stimulates at

Genesis inhibits immune surveillance and

bio mentally regulation so you can see

how the levels are coming from benefits

inside the cell our cell to cell

interaction and how they're in effects

that effects the whole system very

unique so while collecting three inside

the nucleus of the cell has important

issues when it comes into the cytoplasm

of the cell when it comes outside it

really serves to repair injury and it

repairs injury by causing inflammation

and fibrosis the attended the trial

mental effect on every chronic condition

and the initial interest was

specifically on cancer and we've been

studying now the effect of corrected to

be blocker mod affected expected in

prostate cancer for 23 years so this is

really how we talked about these tweaks

we categorize and you can see how

together they will just make cancer

survive and become more aggressive so

what is more effective especially

picketing is a low

complex chain of a polysaccharide fiber

electronic acid you can see it below the

blue chart

most of it is terrified the one in green

and a few of them are not as terrifying

and it is neutral sugars like randos

arabinose which are very many components

like new recognition or detoxification

also is ramlak electron and - I mean our

specific modified citrus pectin we

published with the USDA

10% from the electron and - which is a

compound present in mistletoe which

meaning Union answer so in order for it

to be beneficial we have to cut it to a

very low molecular weight so it didn't

get easily absorbed by the GI tract and

we have to create a certain structure

that will be biologically active and

will exert its benefits and we have

shown now by developing an antibody to

our modifies it was effective that it

can actually be absorbed into the blood

work and create its benefit and let me

say a word about modified it was good

it's really a generic chain name because

every patient is to be modified to be

produced it is to be pulled out of the

peel and is our research continues as we

now just finishing two double-a clinical

trials on osteoarthritis in hypertension

with Harvard is we published more than

40 papers on our specific motivated

respect in Invictus or see there's a lot

of powered science so you really want to

make sure that you are using the

specific preparation that was research

entities whether the discoveries were

were made of because it's a really

important dietary supplement fiber which

is a must for every person so I'm just

touching very briefly of the research

and what offensive respect and in

prostate cancer especially on their two

most important you're maintaining that

our phase two pilot study was done on

ten men with biochemical posted cancer

relapse using 15 percent 15 gram and

days for one year these patients were

off any drugs for six months and we had

a very significant improvement in the

study

these are study with biochemical relapse

which means the prostate was removed

there is no prostate and PSA zero or

next to zero and then it starts coming

back as a cancer occurs and it reoccurs

the speed of elevation of L fare of PSA

is proportional to the growth of cancer

well-established and we're able to slow

it down to increase

the time it takes for the PSA to double

in seven out of ten men

his p-value under 0.01 with the AIDS one

in there if it was under 0.05 so you can

see that even there even a pro patient

number four still and it's slowing down

of the process but it wasn't under 0.01

and these are all patient with seeking

clinically significant prostate cancer

which is growing fast why is this so

important

that's another compounded came down PSA

because if we do it in a non hormonal

mechanism we do it without manipulating

the hormonal picture because once we

change so model expression of constant

cancer we start messing up with the

biology of the cancer modified it to

speak is so unique that it binds to

collected 3 it it shuts down all of this

aggressive mechanisms it enhances the

immune system it removes heavy metals

and it can do it on a long-term basis

because not hormonal e involved we

developed hormonal adjustments so

interesting the same data was presented

actually no this is a different slide I

was going to show you another flap adult

secretion in this time there's an

example of one of the patients so if we

were just affecting the metastasis you

get a straight line because the primary

tumor will still grow but you can see

where the error is at the moment we

start eating modified it respected we

checked it for six months before it was

a straight line linear increase it

immediately affects the PSA rise which

means it's affecting the growth of the

primary tumor and the metastatic process

and that's because of its anti

angiogenesis and will develop these

patients 20 months look how it's

flattening at the end so you understand

every day

the modified retrospective slows down

the growth of cancer is an eighth day of

life because we are not messing with the

hormonal mechanic

which creates mutated tumors and more

questions so we are now we've been

engaged now for four years in what was

supposed to be a shade three

double-blind clinical trial but because

it's low in treatment was changed to

face to be multicenter perspective they

study that he's testing the

effectiveness of motivated inspecting in

the treatment of PSA dynamics in all

metastatic biochemically we'll have to

post it again I'm just reading you the

title from the ASCO 2018 poster

presentation and this was a pre-planned

analysis of fare 50% of the patients and

so after we have 50% of more than 50% of

the patient finished six months we are

presenting it and we expect in these

patients that 80% of the patients will

progress in six months and right now we

already had 45 patient enrolled and we

hope to publish data on 50 patients so

longer term data so what did we do in

this study we took patient with

biochemically when limits relapse

prostate cancer after primary tumor

treatment either surgery radiation of

both we confirmed rising PSA monthly

time 3 so we had a straight line and we

could calculate the doubling time we

confirmed that testosterone is at normal

levels there is no unwritten deprivation

treatments for at least 3 months and the

PET scan of Vaughn scan

law CT scans are negative patient were

evaluated monthly and they were

receiving 6 months of oral mCP therapy

for my Datagram 3 times a day and

disease status piercing scams at 6

months and then we divided it - no

progression which means it stopped going

up remember hundred percent of these

patients are progressive right now and

if they progress they were taken of the

study and when we in progression we

define

25% increase in PSA from baseline our

skin progression on limiting toxicity

and I want to mention it's a little bit

of an issue because if you can have

somebody and if somebody who's PC is

going up very quickly you improve them

but they still went up by 25% during the

six four months let's say because before

they will go up by 50% and still they

will not qualify even if you're actually

helping so the results were fascinating

first of all in general 79% of the 34

patient benefited from modified citrus

pectin which is remarkable out of these

out of these patients a 62 percent of

the hundred percent out of the 79

percent most of them create 60 percent

out of a hundred that was the PI of 79%

and I can't show you in the pointer

because it's on your screen 62 percent

the PSA became slept or went down 17

percent it continued to go up but slower

than before only 21% of the patient did

no PSA doubling time improvement most of

them just the PSA going up and only nine

percent had a change in finding the skin

so this very strongly confirmed our

observation of the benefit of modified

citrus pectin so again to summarize

they're all patient and persecuting

rightly VPSA

62 percent had no progression 2134

stable or decreasing PSA levels and

there were no safety issues the most

common side effect was bloating which is

dose dependent it usually goes away so

very exciting very exciting confirmation

of the benefits of but what was

interesting for us is they to here what

is the impression of some patients who

have been involved in the study for a

long time the studies for six months if

you get results you continue for one

year but as you can see people who are

done with the stylus keep on using the

product

insane even some people who didn't get

for one reason

which supposedly progressed end of

subtitle so it's interesting to read

like you know if the the first person in

the last two years I consume because all

see three times a day I feel energetic

this good moded appetite the overall

feeling is much better than the previous

period Pierce has been stable for 18

months and interesting but what's

interesting for us is that it's a

reflection of this approach of the

wisdom of nature the decide effect of of

using something like modified it

respective for unique to modifies it

respected and it somebody feels more

energetic in Goodwood and overall

feeling is much better the other person

he took MCT consistently for two years

and after three months this PSA was

better and no skin evidence of I mean

humor until today two years but he said

I literally feel an improvement in my

health and fitness feel good stop for

two months PSA went up and then when it

restarted it stopped again what's

interesting about it is this feeling

good feeling better

less joint pain better memory better

mood it all relates to blocking the

effects of collectings me that's why if

you look at charts of my patient seven

eight years ago

I recommend of course - I said respect

him but you would not see it at the top

of the lease it was one of her important

things I now feel strongly that every

person needs to take motivated

respecting because what I started

respecting is directly related to aging

into every chronic disease the topic

today is prostate cancer a budget and

there that's what we'll focus with the

dosing but for me it's the number one

supplement that people need to take so

if we look at how to use modified citrus

pectin

there for people with active prostate

issues especially cellular issues you

can use one scoop three times a day or

one and a half scoops twice a day which

is equivalent to six capsules or calling

or Connie to guidance from your own

health pearl

petitioner and you can also you can also

when using depict us or see if using it

just for prevention from good health

then five grams is very effective it's

really useful it's important to

understand it and good to be taken on

empty stomach but even 15 20 minutes

before food is okay

and if across decades for posted health

because an active serious condition you

can go up to six capsules twice a day

maintenance is two capsules vitally and

we have published on the synergistic

effect between poster Kade and pizza

sauce so to summarize our webinar better

post a BPH benign prostatic hypertrophy

and take 50% of men over 50 90 % of men

over 80

bps symptoms significantly impact

quality of slides posted cancer is the

most common cancer in men we talked a

little bit a little bit in depths in a

quick way about a little bit of a

different way of looking at constant

concern and we talked to the evidence

about the benefits of course decade we

create and manifested respecting so

important in prostate cancer so I thank

you very much if you need any questions

please say please the same to influence

better publishing I want to think better

of publishing from hosting me I got

quite a few questions which I will

answer may be in writing but one

question that I got a few of them is

which I kind of answered is is the use

of mod affected respecting restricted to

prostate cancer and the answer is

obviously not it's not restricted just

to prostate cancer with evidence

multiple cancers because of the

collecting 3 but it really addresses

inflammation and fibrosis which drives

chronic disease the other part is does

modified see prospective remove heavy

metal it's another question yes if a

number of clinical trials showing the

body size in perspective and we move

heavy metals with late being a leading

one but also mercury other

once anyone that now positively charged

so I want to thank everybody for your

time and we will after reading after

reading the questions we'll get back to

you in writing and I hope to see you or

hear us out for you to join me again for

other topics which I hope to offer now

more frequently