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These are the user uploaded subtitles that are being translated: 1 00:00:22,360 --> 00:00:27,596 I felt this connection with everything, 2 00:00:27,620 --> 00:00:28,675 especially with nature. 3 00:00:31,340 --> 00:00:33,806 I have understood for a long time that change is part 4 00:00:33,830 --> 00:00:36,806 of the essential nature of the universe and that I've always 5 00:00:36,830 --> 00:00:39,616 been afraid of change. 6 00:00:39,640 --> 00:00:42,820 But today, I felt deeply that change is a gift. 7 00:00:45,480 --> 00:00:47,796 I wish I could put it into words. 8 00:00:47,820 --> 00:00:53,856 It was a sense of connectedness that runs through all of us 9 00:00:53,880 --> 00:00:58,746 and also a sense of the strength of it and the power of it. 10 00:00:59,655 --> 00:01:01,388 DvX3M www.opensubtitles.org 11 00:01:08,790 --> 00:01:11,506 Mystical experience has been a part of human nature as far 12 00:01:11,530 --> 00:01:12,307 as we know. 13 00:01:12,331 --> 00:01:15,276 And most major religions and religion traditions, 14 00:01:15,300 --> 00:01:19,236 at the core, were about a mystical experience. 15 00:01:19,260 --> 00:01:25,056 Mysticism is unlike a belief in something or knowledge 16 00:01:25,080 --> 00:01:26,496 based on what someone tells you. 17 00:01:26,520 --> 00:01:29,436 It's the direct experience of that thing, 18 00:01:29,460 --> 00:01:32,586 what's been called the ground of being, to quote, Paul Tillich, 19 00:01:32,610 --> 00:01:37,276 or all that is, in Hinduism, or in Christianity, 20 00:01:37,300 --> 00:01:38,606 Christ-consciousness. 21 00:01:38,630 --> 00:01:40,696 It's a direct experience with all 22 00:01:40,720 --> 00:01:43,180 that is with nature, with God, as some would call it. 23 00:01:52,950 --> 00:01:55,836 The word psychedelic means "mind manifesting," 24 00:01:55,860 --> 00:01:58,026 and it came from a poem. 25 00:01:58,050 --> 00:02:01,116 "To fathom hell or sorrow angelic, 26 00:02:01,140 --> 00:02:03,320 just take a pinch of psychedelic." 27 00:02:07,840 --> 00:02:10,606 The word psychedelic was coined by a psychiatric 28 00:02:10,630 --> 00:02:14,386 researcher named Humphry Osmond in a letter to author Aldous 29 00:02:14,410 --> 00:02:19,276 Huxley in 1956, before Timothy Leary, Ken Kesey, 30 00:02:19,300 --> 00:02:20,866 or the hippie movement. 31 00:02:20,890 --> 00:02:23,626 And yet the use of psychedelics goes back long 32 00:02:23,650 --> 00:02:25,816 before the 20th century. 33 00:02:25,840 --> 00:02:28,276 For as long as humans have been roaming the Earth, 34 00:02:28,300 --> 00:02:31,075 they've ingested and worshipped these mysterious plants. 35 00:02:46,670 --> 00:02:48,986 In the 16th and 17th centuries, 36 00:02:49,010 --> 00:02:51,686 when the Spanish conquistadors arrived in the New World, 37 00:02:51,710 --> 00:02:55,076 they were horrified by what they observed. 38 00:02:55,100 --> 00:02:58,586 They saw the native people using a vast pharmacopeia 39 00:02:58,610 --> 00:03:02,996 of native plants for purposes of healing and divination. 40 00:03:03,020 --> 00:03:05,936 And this was entirely in conflict 41 00:03:05,960 --> 00:03:08,786 with the orthodox, rigid belief system 42 00:03:08,810 --> 00:03:11,486 that conquistadors brought with them. 43 00:03:11,510 --> 00:03:14,216 The mushroom ceremonies happened at night. 44 00:03:14,240 --> 00:03:18,116 They involved invoking spirits, divining the future, 45 00:03:18,140 --> 00:03:19,706 looking for lost things. 46 00:03:19,730 --> 00:03:22,251 And there were women who were doing the ceremonies as well 47 00:03:22,275 --> 00:03:23,052 as men. 48 00:03:23,076 --> 00:03:25,736 So so many things, probably, about that culture 49 00:03:25,760 --> 00:03:27,386 was shocking. 50 00:03:27,410 --> 00:03:29,996 And certainly, in Christianity, the power 51 00:03:30,020 --> 00:03:34,226 is given to priests who speak on behalf of God. 52 00:03:34,250 --> 00:03:36,571 And so the thing that is scary about psychedelics 53 00:03:36,595 --> 00:03:38,345 is that it gives power directly to people. 54 00:03:40,970 --> 00:03:43,916 The inquisition, in the year 1616, 55 00:03:43,940 --> 00:03:47,336 formally condemned the use of hallucinogenic plants 56 00:03:47,360 --> 00:03:50,846 and stated that the punishment for anyone who would use such 57 00:03:50,870 --> 00:03:55,106 plants, whether they be natives or immigrant Spaniards, 58 00:03:55,130 --> 00:03:58,430 was death by the cruelest methods available. 59 00:04:01,990 --> 00:04:02,927 1938. 60 00:04:10,230 --> 00:04:14,076 In 1938, as Europe stood on the brink of world war, 61 00:04:14,100 --> 00:04:16,476 a chemist working for a pharmaceutical company 62 00:04:16,500 --> 00:04:19,685 in Switzerland made a most unusual discovery, 63 00:04:19,709 --> 00:04:23,616 one that would alter the course of human events to come. 64 00:04:23,640 --> 00:04:25,626 Albert Hofmann was, from a young person, 65 00:04:25,650 --> 00:04:29,766 very focused on nature, kind of a nature mystic almost. 66 00:04:29,790 --> 00:04:32,616 And he worked at Sandoz Pharmaceutical Companies. 67 00:04:32,640 --> 00:04:36,516 And they were looking... in 1938 is when he invented LSD. 68 00:04:36,540 --> 00:04:39,186 It was also from ergot, which is a fungus that 69 00:04:39,210 --> 00:04:40,836 grows on wheat and barley. 70 00:04:40,860 --> 00:04:42,936 He was looking at various compounds 71 00:04:42,960 --> 00:04:45,276 where he could start with what was in ergot 72 00:04:45,300 --> 00:04:46,986 and manipulate them in different ways. 73 00:04:47,010 --> 00:04:50,136 And LSD-25 was the 25th variation. 74 00:04:50,160 --> 00:04:52,686 And in 1943, five years later, he 75 00:04:52,710 --> 00:04:55,956 had what he called a peculiar presentiment that there was 76 00:04:55,980 --> 00:05:00,846 something worthwhile in LSD-25. 77 00:05:00,870 --> 00:05:02,616 He accidentally ingested some, 78 00:05:02,640 --> 00:05:07,636 because you don't need that much LSD to get into your system. 79 00:05:07,660 --> 00:05:13,086 And he had a really unexpected experience. 80 00:05:13,110 --> 00:05:16,026 It wasn't anything that blew his mind, 81 00:05:16,050 --> 00:05:18,066 but it was enough that he paid attention. 82 00:05:18,090 --> 00:05:19,396 It was on a Friday. 83 00:05:19,420 --> 00:05:22,116 And so he went home over the weekend. 84 00:05:22,140 --> 00:05:25,386 And on Monday, April 19, 1943, he 85 00:05:25,410 --> 00:05:28,086 decided that he would do a planned experiment, 86 00:05:28,110 --> 00:05:30,516 and he would take an amount that he 87 00:05:30,540 --> 00:05:33,456 said was so small that he thought nothing would happen. 88 00:05:33,480 --> 00:05:35,256 But he wanted to be extra cautious. 89 00:05:35,280 --> 00:05:38,166 And that turned out to be 250 micrograms, 90 00:05:38,190 --> 00:05:40,246 250 millionths of a gram. 91 00:05:40,270 --> 00:05:42,876 Which 100 micrograms is usually enough for someone 92 00:05:42,900 --> 00:05:49,081 who's naive to LSD to have a full-blown experience. 93 00:05:49,105 --> 00:05:52,776 Some of the symptoms occurred immediately, 94 00:05:52,800 --> 00:05:57,246 and very soon to become very, very strong, very intense. 95 00:05:57,270 --> 00:06:04,296 And I became anxious, and I asked my laboratory assistant 96 00:06:04,320 --> 00:06:07,006 to accompany me home. 97 00:06:07,030 --> 00:06:13,466 And then, we went home by bicycle because it was wartime, 98 00:06:13,490 --> 00:06:16,116 and of course, I had no car. 99 00:06:16,140 --> 00:06:19,536 And I reported about this bicycle ride 100 00:06:19,560 --> 00:06:25,266 because I had the feeling that time would stand still. 101 00:06:32,820 --> 00:06:35,626 It's quite an extraordinary property of LSD, 102 00:06:35,650 --> 00:06:39,496 and yet that's a very, very deep meaning. 103 00:06:39,520 --> 00:06:42,436 If you have such a deep affect of your whole body, 104 00:06:42,460 --> 00:06:45,346 of your consciousness, of your senses, 105 00:06:45,370 --> 00:06:50,895 LSD must attack the very center of our psychic existence. 106 00:06:55,450 --> 00:06:59,216 Hofmann feared that his nightmare would never end, 107 00:06:59,240 --> 00:07:01,736 that he had permanently damaged his mind, 108 00:07:01,760 --> 00:07:04,466 and wondered what his wife and children would think when they 109 00:07:04,490 --> 00:07:08,426 returned home to find a madman in the living room. 110 00:07:08,450 --> 00:07:10,436 Slowly, the effects wore off. 111 00:07:10,460 --> 00:07:13,196 And after a night's rest, he entered his garden, 112 00:07:13,220 --> 00:07:16,286 where everything was teeming with life. 113 00:07:16,310 --> 00:07:19,946 Woke up the next day and felt refreshed, rejuvenated. 114 00:07:19,970 --> 00:07:21,956 He found things to be novel and interesting. 115 00:07:21,980 --> 00:07:24,956 He went back to the lab to figure out what had happened. 116 00:07:24,980 --> 00:07:28,556 Nobody had thought that anything in terms of the microgram range 117 00:07:28,580 --> 00:07:30,396 could create an effect. 118 00:07:30,420 --> 00:07:33,146 But in fact, he discovered this very potent compound. 119 00:07:33,170 --> 00:07:36,266 And then, Sandoz Pharmaceuticals tested it in animals 120 00:07:36,290 --> 00:07:38,224 for safety and toxicity, then tested it 121 00:07:38,248 --> 00:07:40,266 in some of the members of Sandoz Pharmaceuticals. 122 00:07:40,290 --> 00:07:44,786 But in 1943, Hofmann became temporarily psychotic through 123 00:07:44,810 --> 00:07:47,096 accidental ingestion of the drug. 124 00:07:47,120 --> 00:07:49,466 The door swung wide open for research 125 00:07:49,490 --> 00:07:52,136 into the nature of the schizophrenic process, 126 00:07:52,160 --> 00:07:56,036 and in a larger sense, into the biochemistry of psychosis. 127 00:07:56,060 --> 00:08:01,706 They believed that it might be a tool to help psychiatrists 128 00:08:01,730 --> 00:08:05,486 understand the inner experience of their psychotic 129 00:08:05,510 --> 00:08:06,986 or schizophrenic patients. 130 00:08:07,010 --> 00:08:11,186 So they packaged samples of LSD and shipped them out 131 00:08:11,210 --> 00:08:14,916 to the leading psychiatric researchers around the world. 132 00:08:14,940 --> 00:08:19,106 I'm going to give you this cup that contains lysergic 133 00:08:19,130 --> 00:08:21,746 acid, 100 microgram. 134 00:08:21,770 --> 00:08:25,016 suggesting that they try this compound themselves, 135 00:08:25,040 --> 00:08:27,926 that it was a psychotomimetic drug, 136 00:08:27,950 --> 00:08:31,676 that it would induce the kind of psychotic experience that 137 00:08:31,700 --> 00:08:35,666 their patients were going through and would better help 138 00:08:35,690 --> 00:08:39,236 them understand and so better help them treat. 139 00:08:39,260 --> 00:08:40,405 How you feel? 140 00:08:40,429 --> 00:08:43,106 Well, I feel very fine. 141 00:08:43,130 --> 00:08:45,596 I feel very buoyant and light and resilient. 142 00:08:45,620 --> 00:08:49,356 I feel as though this chair is not solid. 143 00:08:49,380 --> 00:08:50,636 It seems to be... 144 00:08:50,660 --> 00:08:55,586 I have a feeling that my hands are not 145 00:08:55,610 --> 00:08:58,236 resting against this chair. 146 00:08:58,260 --> 00:09:00,486 And I see flashes of color quite a bit. 147 00:09:00,510 --> 00:09:03,576 I see this rug, for example, seems 148 00:09:03,600 --> 00:09:05,796 to have an awful lot of complements 149 00:09:05,820 --> 00:09:08,526 of violet and yellow. 150 00:09:08,550 --> 00:09:12,216 It seems to feel that I'm going to watch it. 151 00:09:12,240 --> 00:09:16,056 Now, as it turned out, the experience is not at all like 152 00:09:16,080 --> 00:09:18,726 what the inner experience of a schizophrenic is. 153 00:09:18,750 --> 00:09:21,936 Now, when you look at your hands, do as I do. 154 00:09:21,960 --> 00:09:25,276 Close your eyes, and just concentrate on your hands. 155 00:09:25,300 --> 00:09:26,077 There it is. 156 00:09:26,101 --> 00:09:29,046 I feel these lovely colors vibrating all over me. 157 00:09:29,070 --> 00:09:30,036 It's lovely. 158 00:09:30,060 --> 00:09:30,976 Any lines? 159 00:09:31,801 --> 00:09:33,366 Any forms? 160 00:09:33,390 --> 00:09:36,456 Just like the shimmering water, you know? 161 00:09:36,480 --> 00:09:38,506 You can put your hand down now. 162 00:09:38,530 --> 00:09:39,307 Come on. 163 00:09:39,331 --> 00:09:42,186 Describe it. 164 00:09:42,210 --> 00:09:43,574 I don't know. 165 00:09:48,750 --> 00:09:50,270 It's just giving, and... 166 00:09:59,650 --> 00:10:01,852 You don't know. 167 00:10:01,876 --> 00:10:05,636 You want to give yourself... 168 00:10:05,660 --> 00:10:07,984 You want to give yourself as much as you can. 169 00:10:08,008 --> 00:10:10,526 There's all sorts of things happening during a psychedelic 170 00:10:10,550 --> 00:10:11,327 experience. 171 00:10:11,351 --> 00:10:14,486 One thing is that the 5-HT2A receptor, which 172 00:10:14,510 --> 00:10:17,886 is the psychedelic receptor, is being stimulated quite a bit. 173 00:10:17,910 --> 00:10:19,146 And that's mostly serotonin. 174 00:10:19,170 --> 00:10:21,266 But then it turns out that if you stimulate 175 00:10:21,290 --> 00:10:24,686 the 5-HT2A receptor enough, it actually 176 00:10:24,710 --> 00:10:28,706 creates a receptor couple with a whole other transmitter 177 00:10:28,730 --> 00:10:30,356 system, which is oxytocin. 178 00:10:30,380 --> 00:10:32,216 They form what's called a dimer. 179 00:10:32,240 --> 00:10:35,026 They dimerize, and they create a receptor complex. 180 00:10:35,050 --> 00:10:37,026 In a couple, when you fall in love with someone, 181 00:10:37,050 --> 00:10:39,236 there's a lot of oxytocin, and you're open to them, 182 00:10:39,260 --> 00:10:40,646 and you're bonding with them. 183 00:10:40,670 --> 00:10:42,656 With a mother who's nursing a baby, 184 00:10:42,680 --> 00:10:45,296 and there's like maternal infant bonding, 185 00:10:45,320 --> 00:10:46,826 oxytocin is there for that. 186 00:10:46,850 --> 00:10:49,016 I feel very benevolent. 187 00:10:49,040 --> 00:10:53,576 I mean, I feel as though I have no enemies in the world. 188 00:10:53,600 --> 00:10:58,196 And this is very lovely. 189 00:10:58,220 --> 00:11:01,046 And that sense of oneness and unity and connection signifies 190 00:11:01,070 --> 00:11:03,456 sort of the peak of a psychedelic experience. 191 00:11:03,480 --> 00:11:06,671 And when you come away from that, you come away changed. 192 00:11:08,930 --> 00:11:11,756 The insight that I was getting from traditional 193 00:11:11,780 --> 00:11:16,016 and classic Buddhist meditation was similar to the insight that 194 00:11:16,040 --> 00:11:19,406 I'd finally arrived at under the acid. 195 00:11:19,430 --> 00:11:23,336 The lesson was form is emptiness. 196 00:11:23,360 --> 00:11:26,126 There's a sense of emptiness and transitoriness 197 00:11:26,150 --> 00:11:28,946 in all perceived phenomena. 198 00:11:28,970 --> 00:11:31,646 And there's no need to get hysterically 199 00:11:31,670 --> 00:11:34,796 hung up on any thought form, no need to grab. 200 00:11:34,820 --> 00:11:39,326 And there is no enlightenment, no wisdom, no illumination, 201 00:11:39,350 --> 00:11:43,676 no god, no identity, no self, no reference point, 202 00:11:43,700 --> 00:11:47,239 that any grabbing for a reference point is vain. 203 00:11:47,263 --> 00:11:48,656 And that's one of the first things 204 00:11:48,680 --> 00:11:50,114 you think when you get high anyway, 205 00:11:50,138 --> 00:11:51,626 that even if you didn't get high, 206 00:11:51,650 --> 00:11:54,086 you'd be seeing the same reality, that in a sense, 207 00:11:54,110 --> 00:11:55,826 acid is not necessary. 208 00:11:55,850 --> 00:11:58,457 And that's why it's OK. 209 00:12:01,820 --> 00:12:05,966 In the early 1950s, as LSD research was in its infancy, 210 00:12:05,990 --> 00:12:08,786 little was known in the West about naturally-occurring 211 00:12:08,810 --> 00:12:10,736 psychedelics. 212 00:12:10,760 --> 00:12:13,706 In 1953, author Aldous Huxley was 213 00:12:13,730 --> 00:12:16,556 given mescaline, the active ingredient in the peyote 214 00:12:16,580 --> 00:12:21,056 cactus, under the supervision of psychiatrist Humphry Osmond. 215 00:12:21,080 --> 00:12:24,446 Huxley later wrote about this experience in the seminal book 216 00:12:24,470 --> 00:12:26,636 "The Doors of Perception." 217 00:12:26,660 --> 00:12:29,936 And in New York City, a very unlikely character 218 00:12:29,960 --> 00:12:32,936 helped bridge the gap between the ancient traditions 219 00:12:32,960 --> 00:12:35,711 and modern America. 220 00:12:35,735 --> 00:12:39,936 R. Gordon Wasson was a very successful businessman 221 00:12:39,960 --> 00:12:40,737 and banker. 222 00:12:40,761 --> 00:12:43,886 He was a vice president of JP Morgan. 223 00:12:43,910 --> 00:12:47,486 As a young man, he met his future wife, Valentina, 224 00:12:47,510 --> 00:12:48,656 who was Russian. 225 00:12:48,680 --> 00:12:53,516 And she had a great interest and enthusiasm for the collection 226 00:12:53,540 --> 00:12:55,946 of edible mushrooms. 227 00:12:55,970 --> 00:12:58,676 While on their honeymoon in the Catskill Mountains, 228 00:12:58,700 --> 00:13:02,486 Valentina leaped with excitement after spying a cluster of wild 229 00:13:02,510 --> 00:13:05,456 mushrooms growing in the forest. 230 00:13:05,480 --> 00:13:07,706 She sounded off the species name in Russian 231 00:13:07,730 --> 00:13:11,366 and insisted that they prepare them for dinner that night. 232 00:13:11,390 --> 00:13:14,756 Wasson, of Anglo-Saxon heritage, was brought up 233 00:13:14,780 --> 00:13:17,636 to believe mushrooms were poison and was horrified 234 00:13:17,660 --> 00:13:19,856 at his wife's enthusiasm. 235 00:13:19,880 --> 00:13:21,686 This difference in cultural attitudes 236 00:13:21,710 --> 00:13:25,586 became the catalyst for Wasson's lifelong interest in mycology, 237 00:13:25,610 --> 00:13:27,506 or the study of fungi. 238 00:13:27,530 --> 00:13:30,836 And then, in the early '50s, a friend of his wrote him 239 00:13:30,860 --> 00:13:35,426 a letter suggesting he look into an extant mushroom cult 240 00:13:35,450 --> 00:13:37,806 in the central highlands of Mexico, 241 00:13:37,830 --> 00:13:41,861 where he had heard that there was use of hallucinogenic 242 00:13:41,885 --> 00:13:42,662 mushrooms. 243 00:13:42,686 --> 00:13:45,266 Now, this came as quite a surprise to Wasson 244 00:13:45,290 --> 00:13:47,276 because at this time, the early '50s, 245 00:13:47,300 --> 00:13:49,916 it was not believed that there were such things 246 00:13:49,940 --> 00:13:53,686 as hallucinogenic mushrooms. 247 00:13:53,710 --> 00:13:59,386 We went into the Mazatec area far from the highways, 248 00:13:59,410 --> 00:14:01,546 remote from Mexico City. 249 00:14:01,570 --> 00:14:04,096 There we found that rotten bagasse, 250 00:14:04,120 --> 00:14:07,496 as it's called, bagasso, covered with mushrooms. 251 00:14:07,520 --> 00:14:10,846 These mushrooms I didn't know, had never seen. 252 00:14:10,870 --> 00:14:13,426 They were the sacred mushrooms. 253 00:14:13,450 --> 00:14:15,916 After much difficulty, and by some accounts, 254 00:14:15,940 --> 00:14:18,436 manipulation on the part of Wasson, 255 00:14:18,460 --> 00:14:23,086 he eventually found entry into a velada, or mushroom ceremony. 256 00:14:23,110 --> 00:14:25,606 The curandera, or healer, was a woman 257 00:14:25,630 --> 00:14:28,006 named Maria Sabina, who represented 258 00:14:28,030 --> 00:14:30,226 a long line of underground healers 259 00:14:30,250 --> 00:14:33,376 left intact since the days of Spanish conquest. 260 00:14:35,950 --> 00:14:39,976 And we were seeing incredible sights. 261 00:14:40,000 --> 00:14:42,646 All your senses are rendered acute. 262 00:14:42,670 --> 00:14:44,866 We say that you see visions. 263 00:14:44,890 --> 00:14:46,606 You see hallucinations. 264 00:14:46,630 --> 00:14:49,426 But that doesn't begin to tell the story. 265 00:14:49,450 --> 00:14:51,496 The hallucinations are only part of it. 266 00:14:51,520 --> 00:14:52,846 You hear sounds. 267 00:14:52,870 --> 00:14:54,166 You smell things. 268 00:14:54,190 --> 00:14:58,147 The night was thrilling. 269 00:15:04,510 --> 00:15:07,936 The visions were not blurred or uncertain. 270 00:15:07,960 --> 00:15:10,936 I felt that I was now seeing plain, 271 00:15:10,960 --> 00:15:15,796 whereas ordinary vision gives us an imperfect view. 272 00:15:15,820 --> 00:15:19,426 I was seeing the archetypes, the Platonic ideas 273 00:15:19,450 --> 00:15:25,186 that underlie the imperfect images of everyday life. 274 00:15:25,210 --> 00:15:27,406 The thought crossed my mind. 275 00:15:27,430 --> 00:15:29,536 Could the divine mushrooms be the secret 276 00:15:29,560 --> 00:15:31,660 that lay behind the ancient mysteries? 277 00:15:35,660 --> 00:15:37,856 Could the miraculous mobility that I was now 278 00:15:37,880 --> 00:15:41,276 enjoying be the explanation for the flying witches that 279 00:15:41,300 --> 00:15:44,036 played so important a part in the folklore and fairy 280 00:15:44,060 --> 00:15:46,926 tales of northern Europe? 281 00:15:46,950 --> 00:15:50,136 These reflections passed through my mind at the very same time 282 00:15:50,160 --> 00:15:52,026 that I was seeing the visions. 283 00:15:52,050 --> 00:15:54,036 For the effect of the mushrooms is 284 00:15:54,060 --> 00:15:58,026 to bring about a vision of the spirit, a split in the person, 285 00:15:58,050 --> 00:16:01,486 a kind of schizophrenia. 286 00:16:01,510 --> 00:16:04,276 Unbeknownst to Wasson, his trips to Mexico were 287 00:16:04,300 --> 00:16:07,426 infiltrated by a group with more nefarious interests 288 00:16:07,450 --> 00:16:10,126 in the mind-altering effects of psychedelics. 289 00:16:10,150 --> 00:16:12,406 In their neverending search for the miracle weapon, 290 00:16:12,430 --> 00:16:15,706 CIA operatives searched here in the remote mountain areas 291 00:16:15,730 --> 00:16:18,886 of southern Mexico for what up to then had been considered 292 00:16:18,910 --> 00:16:20,986 a myth, magic mushrooms. 293 00:16:21,010 --> 00:16:25,216 And so Gordon Wasson was unwittingly participating 294 00:16:25,240 --> 00:16:29,806 in this sort of military use of psychedelics. 295 00:16:29,830 --> 00:16:33,406 They used this man, a part-time chemist with the CIA, 296 00:16:33,430 --> 00:16:36,136 to dupe this man, a vice president of a bank 297 00:16:36,160 --> 00:16:38,956 and an amateur mycologist, or mushroom expert, 298 00:16:38,980 --> 00:16:41,296 to try to get to the magic mushrooms and turn them 299 00:16:41,320 --> 00:16:42,160 into a drug. 300 00:16:42,184 --> 00:16:44,326 They gave it to several different chemists to try 301 00:16:44,350 --> 00:16:48,446 to figure out what was in it, and nobody could figure it out. 302 00:16:48,470 --> 00:16:50,416 And so they called on Albert Hofmann, 303 00:16:50,440 --> 00:16:52,516 since he had invented LSD. 304 00:16:52,540 --> 00:16:54,196 And they asked him could he figure out 305 00:16:54,220 --> 00:16:57,586 what was in the mushroom that made it so psychedelic. 306 00:16:57,610 --> 00:17:00,166 It would be the amateur, R. Gordon Wasson and his 307 00:17:00,190 --> 00:17:03,226 colleagues, who would win the race and develop the drug 308 00:17:03,250 --> 00:17:07,845 psilocybin from the magic mushrooms. 309 00:17:07,869 --> 00:17:12,106 I think that is very strange that LSD is not just 310 00:17:12,130 --> 00:17:13,786 a laboratory product. 311 00:17:13,810 --> 00:17:19,396 It is closely related with this old Indian magic drug. 312 00:17:19,420 --> 00:17:24,226 That means that LSD belongs pharmacologically, chemically, 313 00:17:24,250 --> 00:17:28,256 to the group of the sacred magic plants of Mexico. 314 00:17:28,280 --> 00:17:31,726 It's a very important finding. 315 00:17:31,750 --> 00:17:34,756 Wasson was friends with Henry Boothe Luce, 316 00:17:34,780 --> 00:17:37,066 who was the publisher of "Life Magazine." 317 00:17:37,090 --> 00:17:40,006 He told his friend Luce about his experience, 318 00:17:40,030 --> 00:17:43,156 and Luce encouraged him to write up his account. 319 00:17:43,180 --> 00:17:47,326 That was really the first word out to Western civilization 320 00:17:47,350 --> 00:17:50,656 that psychedelic mushrooms indeed existed at all. 321 00:17:50,680 --> 00:17:53,926 And it really stimulated growing interest 322 00:17:53,950 --> 00:17:57,886 and led to the psychedelic explosion of the '60s. 323 00:17:57,910 --> 00:18:01,876 Wasson's influence became due in large part to an enigmatic 324 00:18:01,900 --> 00:18:05,026 Harvard psychologist named Timothy Leary. 325 00:18:05,050 --> 00:18:08,656 Though he became known as the most dangerous man in America, 326 00:18:08,680 --> 00:18:12,076 he might have been described by others in the year 1960 327 00:18:12,100 --> 00:18:15,676 as a New England square, a hard-drinking Irishman, 328 00:18:15,700 --> 00:18:19,216 or by himself, an atheist psychologist in the midst 329 00:18:19,240 --> 00:18:20,956 of a midlife crisis. 330 00:18:20,980 --> 00:18:23,816 Timothy Leary was a very prominent researcher 331 00:18:23,840 --> 00:18:24,617 at Harvard. 332 00:18:24,641 --> 00:18:27,436 His California Personality Inventory 333 00:18:27,460 --> 00:18:29,486 is still being used today. 334 00:18:29,510 --> 00:18:32,346 He was sort of a pied piper. 335 00:18:32,370 --> 00:18:34,386 During his early years at Harvard, 336 00:18:34,410 --> 00:18:37,806 Leary was in the throes of personal crisis. 337 00:18:37,830 --> 00:18:41,496 His first wife had committed suicide on his 35th birthday, 338 00:18:41,520 --> 00:18:45,846 reportedly after a strained open marriage. 339 00:18:45,870 --> 00:18:48,116 It was during this time that he described himself 340 00:18:48,140 --> 00:18:51,386 as an anonymous institutional employee who 341 00:18:51,410 --> 00:18:55,106 drove to work each morning in a long line of commuter cars 342 00:18:55,130 --> 00:18:57,986 and drove home each night and drank Martinis, 343 00:18:58,010 --> 00:19:00,116 like several million middle-class, 344 00:19:00,140 --> 00:19:02,636 liberal, intellectual robots. 345 00:19:06,830 --> 00:19:10,736 Inspired by Wasson's article, Leary traveled down to Mexico 346 00:19:10,760 --> 00:19:13,376 with a colleague in 1960 who had found 347 00:19:13,400 --> 00:19:17,116 some mushrooms from a curandero in the mountains. 348 00:19:17,140 --> 00:19:19,006 Leary later said that he learned more 349 00:19:19,030 --> 00:19:21,166 about the brain and its possibilities, 350 00:19:21,190 --> 00:19:24,106 and more about psychology, in the five hours 351 00:19:24,130 --> 00:19:27,646 after taking the mushrooms than he had in the preceding 15 352 00:19:27,670 --> 00:19:31,846 years of studying and doing research in psychology. 353 00:19:31,870 --> 00:19:36,016 When he got back to Harvard, he got permission to do 354 00:19:36,040 --> 00:19:38,056 research with psilocybin. 355 00:19:38,080 --> 00:19:40,826 And that was the beginning of the Harvard Psilocybin Research 356 00:19:40,850 --> 00:19:41,627 Project. 357 00:19:41,651 --> 00:19:43,186 And that was really the beginning 358 00:19:43,210 --> 00:19:46,186 of formal research, attempted clinical research, 359 00:19:46,210 --> 00:19:48,503 of psychedelic agents in the United States. 360 00:19:48,527 --> 00:19:50,836 Timothy Leary had two research products that could go 361 00:19:50,860 --> 00:19:53,496 to the Harvard Psilocybin Research Program. 362 00:19:53,520 --> 00:19:55,466 It was a Good Friday study with Walter Pahnke. 363 00:19:55,490 --> 00:19:59,296 It was a remarkable study and groundbreaking. 364 00:19:59,320 --> 00:20:02,056 They had given psilocybin and a placebo 365 00:20:02,080 --> 00:20:04,576 to 20 graduate students in theology, 366 00:20:04,600 --> 00:20:08,086 comparing their experiences to genuine mystical experiences 367 00:20:08,110 --> 00:20:10,606 found throughout millennia, through mystics and saints. 368 00:20:10,630 --> 00:20:13,906 They arranged to have access to the Marsh Chapel. 369 00:20:13,930 --> 00:20:15,736 It was Good Friday. 370 00:20:15,760 --> 00:20:18,496 They were in a basement chapel. 371 00:20:18,520 --> 00:20:22,336 And the service from upstairs in the main chapel 372 00:20:22,360 --> 00:20:23,551 was being piped through. 373 00:20:29,340 --> 00:20:31,836 The Reverend Howard Thurman was the minister, 374 00:20:31,860 --> 00:20:34,026 who was Martin Luther King's mentor... 375 00:20:34,050 --> 00:20:38,706 This incredible dynamic speaker, orator. 376 00:20:38,730 --> 00:20:45,636 You, Pilate, standing for Rome, are the universal coward. 377 00:20:45,660 --> 00:20:51,096 I, standing for the kingdom of God, have braved everything, 378 00:20:51,120 --> 00:20:59,120 lost everything, and won an eternal crown. 379 00:20:59,460 --> 00:21:01,926 They developed a scale of mystical experience. 380 00:21:01,950 --> 00:21:04,866 Some of the items are a noetic quality, intuitive quality 381 00:21:04,890 --> 00:21:08,136 of understanding things, transcendence of time and space 382 00:21:08,160 --> 00:21:10,906 as we know it, a sense of unity with all living things 383 00:21:10,930 --> 00:21:14,266 internally as well. 384 00:21:14,290 --> 00:21:15,290 I shall die. 385 00:21:18,560 --> 00:21:22,245 But that is all that I shall do for death. 386 00:21:27,320 --> 00:21:30,296 Of the 20 experimental students, 387 00:21:30,320 --> 00:21:33,206 nine out of the 20 people had a mystical experience. 388 00:21:33,230 --> 00:21:36,116 And eight out of those nine had the psilocybin. 389 00:21:36,140 --> 00:21:38,576 It was the first study showing that these agents, 390 00:21:38,600 --> 00:21:40,286 these medicines, these sacraments, 391 00:21:40,310 --> 00:21:43,646 can produce an experience that was found throughout millennia 392 00:21:43,670 --> 00:21:46,136 in various religious traditions. 393 00:21:46,160 --> 00:21:49,034 One young man had a kind of nervous... 394 00:21:49,058 --> 00:21:50,576 I was going to say nervous breakdown, 395 00:21:50,600 --> 00:21:52,496 but it was actually positive for him. 396 00:21:52,520 --> 00:21:55,826 So he was so blown away by this spiritual experience 397 00:21:55,850 --> 00:21:58,166 he was having that he kind of ran out of the chapel. 398 00:21:58,190 --> 00:21:59,874 And he was trying to run to the, I think, 399 00:21:59,898 --> 00:22:02,756 the dean or the president's office to proclaim everything 400 00:22:02,780 --> 00:22:03,926 that he had learned. 401 00:22:03,950 --> 00:22:08,636 And behaved rather bizarrely out in public until the sitters 402 00:22:08,660 --> 00:22:11,486 found him and retrieved him and brought him back. 403 00:22:11,510 --> 00:22:15,416 And he actually had to be sedated with a tranquilizer. 404 00:22:15,440 --> 00:22:17,876 So that's kind of an interesting piece of history 405 00:22:17,900 --> 00:22:19,016 that didn't get reported. 406 00:22:24,640 --> 00:22:28,516 The object of this presentation is to demonstrate 407 00:22:28,540 --> 00:22:33,226 the effect of MER-17, a new blocking agent, 408 00:22:33,250 --> 00:22:37,876 against the development of LSD-25 psychosis. 409 00:22:37,900 --> 00:22:41,656 We have used two healthy graduate students in psychology 410 00:22:41,680 --> 00:22:42,796 as subjects. 411 00:22:42,820 --> 00:22:46,726 When Sandoz discovered the psychoactive effects of LSD, 412 00:22:46,750 --> 00:22:50,596 they also observed that it deepens sort of introspective 413 00:22:50,620 --> 00:22:53,116 insight and can be used in psychotherapy. 414 00:22:53,140 --> 00:22:56,866 So it's a really unique history in the area of drug 415 00:22:56,890 --> 00:23:00,916 research in that there was a heyday of psychedelic research 416 00:23:00,940 --> 00:23:05,476 extending from the 1950s through the early '70s. 417 00:23:05,500 --> 00:23:08,176 Back then, any psychiatric researcher or clinician could 418 00:23:08,200 --> 00:23:12,206 write Sandoz to get a sample of LSD to test it or to use it 419 00:23:12,230 --> 00:23:13,007 clinically. 420 00:23:13,031 --> 00:23:14,836 It was legal and available. 421 00:23:14,860 --> 00:23:17,476 And that really began the big experiment 422 00:23:17,500 --> 00:23:21,406 with LSD that lasted close to 30 years. 423 00:23:21,430 --> 00:23:23,836 In carefully controlled experiments, 424 00:23:23,860 --> 00:23:26,956 interesting results have been reported on the therapeutic use 425 00:23:26,980 --> 00:23:31,246 of LSD with the mentally ill, the drug addict, 426 00:23:31,270 --> 00:23:35,416 the terminal cancer patient, and in the VA hospital in Topeka, 427 00:23:35,440 --> 00:23:40,096 Kansas, a special research program for alcoholics. 428 00:23:40,120 --> 00:23:41,806 We bring them in on one Monday, 429 00:23:41,830 --> 00:23:45,736 and they spend one week of getting acquainted and having 430 00:23:45,760 --> 00:23:48,796 all the tests and examinations done. 431 00:23:48,820 --> 00:23:52,546 The second Monday, we give them a small dose 432 00:23:52,570 --> 00:23:56,296 of LSD in the five-man ward, together. 433 00:23:56,320 --> 00:24:00,166 Then, the third Monday, we give them a larger dose 434 00:24:00,190 --> 00:24:03,916 individually and have each one of them cared 435 00:24:03,940 --> 00:24:06,916 for by one of these teams. 436 00:24:06,940 --> 00:24:10,306 And this is where we aim for the so-called psychedelic 437 00:24:10,330 --> 00:24:11,956 experience. 438 00:24:11,980 --> 00:24:14,746 The best clinical outcomes are with subjects who, 439 00:24:14,770 --> 00:24:18,016 during the course of what was often just a one-session 440 00:24:18,040 --> 00:24:22,486 treatment, during that session, had a psychospiritual epiphany, 441 00:24:22,510 --> 00:24:24,436 a mystical-level experience. 442 00:24:24,460 --> 00:24:27,806 I know I kept fighting the religious music. 443 00:24:27,830 --> 00:24:31,066 I didn't know why then, but Dr. Koren 444 00:24:31,090 --> 00:24:36,016 kept urging me to find out why I was fighting this. 445 00:24:36,040 --> 00:24:38,731 And I remember I was just really scared to death. 446 00:24:43,770 --> 00:24:46,776 And I just reached up, and it was like somebody 447 00:24:46,800 --> 00:24:48,930 grabbed me and brought me up. 448 00:24:52,840 --> 00:24:58,266 And I interpret this as for the first time in my life, 449 00:24:58,290 --> 00:25:00,096 I wanted love. 450 00:25:00,120 --> 00:25:03,686 And I think this is the thing that was probably my biggest 451 00:25:03,710 --> 00:25:06,324 problem is that I thought everybody was forcing it on me, 452 00:25:06,348 --> 00:25:07,640 and I wasn't going to let them. 453 00:25:10,530 --> 00:25:15,096 The amazing thing about LSD is very much its evolutionary 454 00:25:15,120 --> 00:25:18,456 nature, is that it seems to concentrate in areas 455 00:25:18,480 --> 00:25:22,716 of the brain that relate to mammalian and reptilian stages 456 00:25:22,740 --> 00:25:25,356 of evolutionary development which are then experienced 457 00:25:25,380 --> 00:25:29,136 by the person, the fact also that people become aware 458 00:25:29,160 --> 00:25:32,976 of the fact that man is not just a single-dimensional being 459 00:25:33,000 --> 00:25:36,706 in a physical body but exists as a being over many, 460 00:25:36,730 --> 00:25:39,546 many lifetimes at many levels of consciousness beyond 461 00:25:39,570 --> 00:25:41,046 the physical. 462 00:25:41,070 --> 00:25:43,476 And I do feel that, in the future, 463 00:25:43,500 --> 00:25:45,246 there will be centers where people 464 00:25:45,270 --> 00:25:48,546 will be able to go to prepare people for any kind of turning 465 00:25:48,570 --> 00:25:51,126 point or crisis in their life, such as along the lines 466 00:25:51,150 --> 00:25:53,526 of the incredible powerful research 467 00:25:53,550 --> 00:25:56,716 that Stan Grof and Walter Pahnke did at Spring Grove Hospital 468 00:25:56,740 --> 00:25:57,990 with terminal cancer patients. 469 00:26:01,030 --> 00:26:03,936 This is a mental institution, Spring Grove State Hospital 470 00:26:03,960 --> 00:26:05,166 in Baltimore. 471 00:26:05,190 --> 00:26:07,236 It is one of four places in the country where 472 00:26:07,260 --> 00:26:09,456 research on LSD treatment continues 473 00:26:09,480 --> 00:26:11,256 under federal sponsorship. 474 00:26:11,280 --> 00:26:15,306 The tablets in Ott's hand each contain a microscopic trace 475 00:26:15,330 --> 00:26:16,926 of LSD. 476 00:26:16,950 --> 00:26:20,256 To an observer, the atmosphere seems closer to faith healing 477 00:26:20,280 --> 00:26:21,366 than medicine. 478 00:26:21,390 --> 00:26:24,666 So the way in which they really refined the approach is 479 00:26:24,690 --> 00:26:28,416 that they used a two-person team, often a male-female. 480 00:26:28,440 --> 00:26:31,446 They pioneered eight-hour therapy sessions, sometimes 481 00:26:31,470 --> 00:26:33,076 even longer. 482 00:26:33,100 --> 00:26:37,026 It was this very expressive, supportive environment. 483 00:26:37,050 --> 00:26:40,416 It isn't so much the drug as the drug in the context 484 00:26:40,440 --> 00:26:43,386 in which it's used, the expectations, 485 00:26:43,410 --> 00:26:45,996 how the person is held safely while they're under 486 00:26:46,020 --> 00:26:48,456 the influence of it, and the interpretation that's made 487 00:26:48,480 --> 00:26:49,806 afterwards. 488 00:26:49,830 --> 00:26:51,816 I was here under LSD. 489 00:26:51,840 --> 00:26:55,656 This went on for a million miles on both sides, 490 00:26:55,680 --> 00:26:59,976 an endless deep and eternity onto. 491 00:27:00,000 --> 00:27:03,336 And it was just one of the fears I had buried, 492 00:27:03,360 --> 00:27:06,006 and it was a fear of being left alone. 493 00:27:06,030 --> 00:27:08,196 We get very stuck in our ways and sort of rigid 494 00:27:08,220 --> 00:27:09,127 in our thinking. 495 00:27:09,151 --> 00:27:10,668 One of the things the psychedelics do 496 00:27:10,692 --> 00:27:13,836 is they increase cognitive flexibility. 497 00:27:13,860 --> 00:27:16,596 You become less rigid in how you think they quiet 498 00:27:16,620 --> 00:27:19,116 down the default mode network, which 499 00:27:19,140 --> 00:27:23,366 is sort of the self-obsessed, self-serving, how am I doing? 500 00:27:23,390 --> 00:27:24,167 Who am I? 501 00:27:24,191 --> 00:27:25,706 Am I liked? 502 00:27:25,730 --> 00:27:26,707 What did I do yesterday? 503 00:27:26,731 --> 00:27:27,998 What am I going to do tomorrow? 504 00:27:28,022 --> 00:27:31,026 And the psychedelics sort of quiet this narcissism 505 00:27:31,050 --> 00:27:34,416 and neuroticism and allow other parts of the brain 506 00:27:34,440 --> 00:27:37,296 to get more active or to connect with each other. 507 00:27:37,320 --> 00:27:38,796 I feel beautiful. 508 00:27:38,820 --> 00:27:40,146 All right. 509 00:27:40,170 --> 00:27:43,020 I feel squashed with beautiful. 510 00:27:46,290 --> 00:27:50,916 That's a really powerful, useful experience to have. 511 00:27:50,940 --> 00:27:53,526 And it can help people out of a dark place. 512 00:27:53,550 --> 00:27:55,416 If you hadn't been prepared for it, 513 00:27:55,440 --> 00:27:59,136 if you hadn't gone through those weeks of preparation, 514 00:27:59,160 --> 00:28:02,046 would LSD have meant as much? 515 00:28:02,070 --> 00:28:06,396 If I was ill before, I would have been ill, it seems to me, 516 00:28:06,420 --> 00:28:08,136 beyond repair. 517 00:28:08,160 --> 00:28:12,516 I would have been so frightened without the guidance 518 00:28:12,540 --> 00:28:14,616 and the trust and the preparation. 519 00:28:14,640 --> 00:28:16,665 It would have been a tragedy, horrible. 520 00:28:24,140 --> 00:28:28,556 I got interested in LSD therapy when I was in two-year 521 00:28:28,580 --> 00:28:32,216 public health service at the public health prison hospital 522 00:28:32,240 --> 00:28:34,566 in Lexington, Kentucky. 523 00:28:34,590 --> 00:28:37,146 At that time, there was really no good treatment 524 00:28:37,170 --> 00:28:39,066 for narcotic addiction. 525 00:28:39,090 --> 00:28:41,526 Recidivism rate was extraordinarily high. 526 00:28:41,550 --> 00:28:45,876 I think people leaving Lexington had a 90% relapse rate. 527 00:28:45,900 --> 00:28:49,936 And I had read about the studies with alcoholism. 528 00:28:49,960 --> 00:28:52,866 And I thought perhaps LSD might be 529 00:28:52,890 --> 00:28:57,636 useful to provide some lasting change for narcotic addiction. 530 00:28:57,660 --> 00:29:00,696 In looking at the literature at that time, 531 00:29:00,720 --> 00:29:02,916 it looked like that therapists who 532 00:29:02,940 --> 00:29:09,006 had used LSD themselves got much better results than therapists 533 00:29:09,030 --> 00:29:11,176 who had not used LSD themselves. 534 00:29:11,200 --> 00:29:14,346 So I decided to do a controlled study. 535 00:29:14,370 --> 00:29:19,116 I would give LSD to a group of narcotic addicts at Lexington 536 00:29:19,140 --> 00:29:22,626 who volunteered for the study, without having ever taken LSD 537 00:29:22,650 --> 00:29:27,576 myself, to see what impact that the experience might have 538 00:29:27,600 --> 00:29:30,246 on their relation with other prisoners, 539 00:29:30,270 --> 00:29:34,876 with authority figures, with insight about themselves. 540 00:29:34,900 --> 00:29:38,826 And then, my plan was to then take the LSD myself 541 00:29:38,850 --> 00:29:42,696 under supervision from staff at the Addiction Research Center 542 00:29:42,720 --> 00:29:45,516 there who were experienced with the agent 543 00:29:45,540 --> 00:29:48,666 and do a second group. 544 00:29:48,690 --> 00:29:51,896 But unfortunately, when I was getting ready to do that, 545 00:29:51,920 --> 00:29:56,906 the company that made LSD, Sandoz, decided to recall it. 546 00:29:56,930 --> 00:30:02,246 This was around 1965, 1966, because LSD 547 00:30:02,270 --> 00:30:03,980 had become a street drug. 548 00:30:11,120 --> 00:30:14,546 And on streets like this, transactions involving me take 549 00:30:14,570 --> 00:30:16,696 place all the time... 550 00:30:16,720 --> 00:30:20,426 Illegal, of course, but my tabs and caps and sugar 551 00:30:20,450 --> 00:30:23,816 cubes that dissolve in your mind as well as your mouth 552 00:30:23,840 --> 00:30:26,156 are selling every day. 553 00:30:26,180 --> 00:30:31,256 Drop a cap on me, man, and drop out. 554 00:30:31,280 --> 00:30:36,056 But watch it, because the trip can be a trap, too. 555 00:30:36,080 --> 00:30:39,656 You never know where a ticket with me will take you. 556 00:30:39,680 --> 00:30:41,876 Just as pioneers of psychedelic research were 557 00:30:41,900 --> 00:30:44,696 beginning to understand its therapeutic potential, 558 00:30:44,720 --> 00:30:48,296 LSD began to leak out of the laboratory. 559 00:30:48,320 --> 00:30:51,056 The two figures most responsible for its expansion 560 00:30:51,080 --> 00:30:54,866 into the American culture lived on opposite ends of the country 561 00:30:54,890 --> 00:30:57,716 and were from equally different backgrounds. 562 00:30:57,740 --> 00:31:00,956 On the West Coast, Ken Kesey was introduced to LSD 563 00:31:00,980 --> 00:31:06,236 in the late 1950s as part of the CIA's MK-Ultra program. 564 00:31:06,260 --> 00:31:08,346 At the time, I was training for the Olympics. 565 00:31:08,370 --> 00:31:09,966 I made it to be an alternate. 566 00:31:09,990 --> 00:31:10,766 As a wrestler? 567 00:31:10,790 --> 00:31:11,757 Yeah, as a wrestler. 568 00:31:11,781 --> 00:31:14,996 I'd never been drunk on beer, let alone done any drugs. 569 00:31:15,020 --> 00:31:17,006 But this is the American government. 570 00:31:17,030 --> 00:31:18,966 I had a neighbor who was a psychologist. 571 00:31:18,990 --> 00:31:21,366 He was booked to do the experiments that Tuesday. 572 00:31:21,390 --> 00:31:22,167 He chickened out. 573 00:31:22,191 --> 00:31:23,546 He says, you want to do them? $20. 574 00:31:23,570 --> 00:31:24,086 Show up. 575 00:31:24,110 --> 00:31:24,997 They gave them to me. 576 00:31:25,021 --> 00:31:28,939 I did them on every Tuesday for six or eight months. 577 00:31:28,963 --> 00:31:31,106 The government wanted somebody to look in that room. 578 00:31:31,130 --> 00:31:32,246 They said, hey, we got a great room. 579 00:31:32,270 --> 00:31:33,806 We discovered this nice room. 580 00:31:33,830 --> 00:31:36,296 Let's get somebody to go in there and look it over. 581 00:31:36,320 --> 00:31:38,456 Kesey would go on to write "One Flew over 582 00:31:38,480 --> 00:31:41,906 the Cuckoo's Nest" partly based on these experiences, 583 00:31:41,930 --> 00:31:45,356 and later, to host the so-called acid tests with the Merry 584 00:31:45,380 --> 00:31:46,227 Pranksters. 585 00:31:46,251 --> 00:31:49,346 And by that time, the government had said, OK, 586 00:31:49,370 --> 00:31:50,280 stop that experiment. 587 00:31:50,304 --> 00:31:52,946 All these guinea pigs that we've sent up there into outer space, 588 00:31:52,970 --> 00:31:54,386 bring them back down, and don't ever 589 00:31:54,410 --> 00:31:56,428 let them go back up there again, because we don't 590 00:31:56,452 --> 00:31:57,816 like the look in their eyes. 591 00:31:57,840 --> 00:32:02,606 I give the CIA total credit for sponsoring and initiating 592 00:32:02,630 --> 00:32:06,806 the entire consciousness movement counterculture events 593 00:32:06,830 --> 00:32:08,306 of the 1960s. 594 00:32:08,330 --> 00:32:10,556 And on the East Coast was Timothy Leary, 595 00:32:10,580 --> 00:32:13,316 the now-former Harvard psychologist. 596 00:32:13,340 --> 00:32:16,596 He began to distribute the drug beyond his research 597 00:32:16,620 --> 00:32:17,397 subjects. 598 00:32:17,421 --> 00:32:20,066 He began to speak quite openly to the press. 599 00:32:20,090 --> 00:32:23,786 He signed an agreement promising that he would not 600 00:32:23,810 --> 00:32:27,746 give it to any undergraduate students but only to graduate 601 00:32:27,770 --> 00:32:32,546 students who were using it for some appropriate academic 602 00:32:32,570 --> 00:32:33,417 purpose. 603 00:32:33,441 --> 00:32:35,016 And Tim Leary honestly... 604 00:32:35,040 --> 00:32:37,016 I don't think he ever met a rule he didn't like. 605 00:32:37,040 --> 00:32:39,206 And that rule quickly was broken. 606 00:32:39,230 --> 00:32:41,246 The Harvard Administration found out 607 00:32:41,270 --> 00:32:43,166 and summarily dismissed him. 608 00:32:43,190 --> 00:32:49,466 And he became the apostle preaching the religion 609 00:32:49,490 --> 00:32:52,286 of psychedelic drugs. 610 00:32:52,310 --> 00:32:56,546 We teach the science and art of ecstasy. 611 00:32:56,570 --> 00:32:59,156 We teach people how to turn on or how 612 00:32:59,180 --> 00:33:01,406 to go out of their minds. 613 00:33:01,430 --> 00:33:04,556 By turn on, we mean tune in to get 614 00:33:04,580 --> 00:33:08,936 beyond your routine ways of thinking 615 00:33:08,960 --> 00:33:10,676 and acting and experiencing. 616 00:33:10,700 --> 00:33:14,036 We often say that we're teaching people how to use their head. 617 00:33:14,060 --> 00:33:17,353 The point is that in order to use your head, 618 00:33:17,377 --> 00:33:18,710 you have to go out of your mind. 619 00:33:22,480 --> 00:33:25,066 What were your feelings when people like Timothy Leary 620 00:33:25,090 --> 00:33:26,266 and Ken Kesey... 621 00:33:26,290 --> 00:33:30,316 Ken Kesey with his pranksters and Timothy Leary, obviously, 622 00:33:30,340 --> 00:33:32,356 with tune in, turn on, drop out, what 623 00:33:32,380 --> 00:33:35,411 were your feelings, as the chemist who had created this? 624 00:33:35,435 --> 00:33:39,026 I was quite astonished, because when I had discovered 625 00:33:39,050 --> 00:33:43,876 these very deep effects of LSD, never would I have believed 626 00:33:43,900 --> 00:33:46,633 that it would be a pleasure drug on the street... 627 00:33:46,657 --> 00:33:47,716 Never would have believed. 628 00:33:47,740 --> 00:33:50,986 The indians believe that you should take the mushrooms 629 00:33:51,010 --> 00:33:53,716 only if you are prepared. 630 00:33:53,740 --> 00:33:56,746 And then only do the mushrooms bring you 631 00:33:56,770 --> 00:33:58,666 in contact with the gods. 632 00:33:58,690 --> 00:34:02,746 If you are not prepared, then it makes you crazy, 633 00:34:02,770 --> 00:34:05,146 or you may even die. 634 00:34:05,170 --> 00:34:08,401 That is a belief of the Indians based on thousands 635 00:34:08,425 --> 00:34:10,179 of years of experience. 636 00:34:13,230 --> 00:34:17,405 Drugs are subversive, and psychedelics are the most 637 00:34:17,429 --> 00:34:19,326 subversive of all the drugs. 638 00:34:19,350 --> 00:34:21,546 And he was labeled most dangerous man 639 00:34:21,570 --> 00:34:26,526 in America because of these very powerful and very subversive 640 00:34:26,550 --> 00:34:28,385 drugs and ideas. 641 00:34:28,409 --> 00:34:31,546 Many of my colleagues have maintained a rather harsh view 642 00:34:31,570 --> 00:34:32,347 of Leary. 643 00:34:32,371 --> 00:34:34,655 They blame him for the repression 644 00:34:34,679 --> 00:34:37,548 of psychedelic research in the '60s. 645 00:34:37,572 --> 00:34:39,006 We shouldn't lose sight of the fact 646 00:34:39,030 --> 00:34:41,556 of the degree to which psychedelics in the culture 647 00:34:41,580 --> 00:34:45,846 were associated with a very vigorous antiwar movement. 648 00:34:45,870 --> 00:34:47,826 The kind of turn on, tune in, drop out, 649 00:34:47,850 --> 00:34:49,493 that phrase gets a bad rap. 650 00:34:49,517 --> 00:34:51,576 But if you look at what was happening at the time, 651 00:34:51,600 --> 00:34:53,945 I think the call was for young people 652 00:34:53,969 --> 00:34:56,241 to not buy into the status quo. 653 00:34:58,353 --> 00:35:00,746 Some people talk about the counterculture as being this 654 00:35:00,770 --> 00:35:03,506 romantic, even religious movement, 655 00:35:03,530 --> 00:35:06,386 that you're talking about using these means to free yourself up 656 00:35:06,410 --> 00:35:09,326 from the distractions of the world so that you can transcend 657 00:35:09,350 --> 00:35:12,296 it and think about ultimate questions about human 658 00:35:12,320 --> 00:35:13,257 existence. 659 00:35:13,281 --> 00:35:16,550 And that's really what Leary was totally talking about. 660 00:35:18,807 --> 00:35:20,866 What we're thinking about is a peaceful planet. 661 00:35:20,890 --> 00:35:22,221 We're not thinking about any kind of power. 662 00:35:22,245 --> 00:35:24,546 We're not thinking about revolution or war or any 663 00:35:24,570 --> 00:35:25,956 of that. 664 00:35:25,980 --> 00:35:27,606 We would all like to be able to live 665 00:35:27,630 --> 00:35:31,056 an uncluttered life, a simple life, a good life, 666 00:35:31,080 --> 00:35:35,017 and think about moving the whole human race ahead a step. 667 00:35:38,650 --> 00:35:40,276 They're taking it in sugar cubes. 668 00:35:40,300 --> 00:35:41,896 It's being dropped into their punch. 669 00:35:41,920 --> 00:35:43,396 They're going to institutions. 670 00:35:43,420 --> 00:35:46,897 They're swell for the rest of their life. 671 00:35:50,660 --> 00:35:55,706 God, no, no, no, no! 672 00:35:55,730 --> 00:35:58,146 Authorities felt they had a public health crisis 673 00:35:58,170 --> 00:35:58,947 on their hands. 674 00:35:58,971 --> 00:36:01,226 And these were also catalysts for change. 675 00:36:01,250 --> 00:36:02,966 And the changes they were inducing 676 00:36:02,990 --> 00:36:05,576 were often perceived in a very threatening manner 677 00:36:05,600 --> 00:36:06,956 by those in authority. 678 00:36:06,980 --> 00:36:12,176 This moral decay weakens our resistance to the onslaught 679 00:36:12,200 --> 00:36:15,086 of the communist masters of deceit. 680 00:36:15,110 --> 00:36:16,916 We've got to do something about this. 681 00:36:16,940 --> 00:36:17,940 Don't you think so? 682 00:36:21,250 --> 00:36:25,846 The drug war is based on demonizing drugs and demonizing 683 00:36:25,870 --> 00:36:27,166 drug users. 684 00:36:27,190 --> 00:36:29,596 Nixon said that the two main enemies that he had 685 00:36:29,620 --> 00:36:32,686 were the Civil Rights Movement and the hippies. 686 00:36:32,710 --> 00:36:36,256 And so while you couldn't criminalize the ideas 687 00:36:36,280 --> 00:36:37,786 that they were struggling for, you 688 00:36:37,810 --> 00:36:40,186 could criminalize the drugs that they were using. 689 00:36:40,210 --> 00:36:43,696 We must wage what I have called total war against public 690 00:36:43,720 --> 00:36:46,396 enemy number one in the United States, 691 00:36:46,420 --> 00:36:47,740 the problem of dangerous drugs. 692 00:36:50,770 --> 00:36:54,556 Richard Nixon declared war on drugs, and Congress, in 1970, 693 00:36:54,580 --> 00:36:56,236 passed the Controlled Substance Act, 694 00:36:56,260 --> 00:36:58,816 which essentially put all serotonergic hallucinogens, 695 00:36:58,840 --> 00:37:02,146 like LSD and psilocybin, into this very restrictive category 696 00:37:02,170 --> 00:37:06,376 of Schedule I, which means highest addictive liability, 697 00:37:06,400 --> 00:37:08,626 no therapeutic utility. 698 00:37:08,650 --> 00:37:11,416 And that was really the beginning of the war on drugs 699 00:37:11,440 --> 00:37:13,846 that we now have for the last 40 years, which 700 00:37:13,870 --> 00:37:17,336 has created a real problem. 701 00:37:17,360 --> 00:37:19,886 At the time, something like 123 million prescriptions were 702 00:37:19,910 --> 00:37:23,156 written by psychiatrists and doctors for tranquilizers. 703 00:37:23,180 --> 00:37:25,346 And more people are killed in car crashes 704 00:37:25,370 --> 00:37:29,396 because they're drunk then die because of LSD. 705 00:37:29,420 --> 00:37:33,026 What kind of drugs are OK and what aren't is a very political 706 00:37:33,050 --> 00:37:34,226 question. 707 00:37:34,250 --> 00:37:37,946 Abuse of hard drugs began to replace mind-expanding agents, 708 00:37:37,970 --> 00:37:41,666 and LSD faded from the culture almost as quickly as it had 709 00:37:41,690 --> 00:37:42,800 exploded into it. 710 00:37:48,060 --> 00:37:51,606 By the 1970s, all remaining psychedelic studies 711 00:37:51,630 --> 00:37:54,136 had been shut down. 712 00:37:54,160 --> 00:37:57,466 In 1972, '73, I had left school, 713 00:37:57,490 --> 00:38:02,146 and I got a job as a research assistant in a dream research 714 00:38:02,170 --> 00:38:05,366 study at Maimonides Medical Center in Brooklyn. 715 00:38:05,390 --> 00:38:10,456 And my job was to stay up all night and monitor sleep EEGs. 716 00:38:10,480 --> 00:38:13,456 And every time our subject went into a dream, 717 00:38:13,480 --> 00:38:15,986 I would wake them up over an intercom system, 718 00:38:16,010 --> 00:38:17,936 ask them what was going through their mind, 719 00:38:17,960 --> 00:38:19,816 and tape record the dreams. 720 00:38:19,840 --> 00:38:22,966 But this also meant I had a lot of time during the night, 721 00:38:22,990 --> 00:38:25,006 and I love to read. 722 00:38:25,030 --> 00:38:28,576 And one of the researchers in his office, he 723 00:38:28,600 --> 00:38:30,946 had a tremendous collection of books and articles 724 00:38:30,970 --> 00:38:32,416 on psychedelics. 725 00:38:32,440 --> 00:38:34,816 And I read voraciously. 726 00:38:34,840 --> 00:38:37,156 Now, at that time, my father was very 727 00:38:37,180 --> 00:38:39,826 concerned about what he thought was my lack of direction. 728 00:38:39,850 --> 00:38:42,106 And he had told me that when I figure out 729 00:38:42,130 --> 00:38:44,806 what I wanted to do with my life, I should call him. 730 00:38:44,830 --> 00:38:47,056 It didn't matter what time of the day or night it was. 731 00:38:47,080 --> 00:38:48,676 He wanted me to call him. 732 00:38:48,700 --> 00:38:52,036 So there I was, at 2 or 3 o'clock in the morning, 733 00:38:52,060 --> 00:38:55,166 just so impressed by what they had done. 734 00:38:55,190 --> 00:38:56,956 I felt I wanted to do this also. 735 00:38:56,980 --> 00:39:00,196 I woke him up from a deep sleep, and I said, Dad, 736 00:39:00,220 --> 00:39:01,796 I figured out what I want to do. 737 00:39:01,820 --> 00:39:03,526 And he said, well, what's that, son? 738 00:39:03,550 --> 00:39:06,206 I said, I want to study psychedelics. 739 00:39:06,230 --> 00:39:07,037 Well, why is that? 740 00:39:07,061 --> 00:39:08,666 Well, they're fascinating. 741 00:39:08,690 --> 00:39:12,556 There's so much we could learn about the brain, about 742 00:39:12,580 --> 00:39:15,016 the mind-brain interface, about mental illness. 743 00:39:15,040 --> 00:39:17,806 And there are these extraordinary treatment models. 744 00:39:17,830 --> 00:39:21,286 And people who conventional treatments cannot help or help 745 00:39:21,310 --> 00:39:22,366 with this model. 746 00:39:22,390 --> 00:39:25,006 And he said, well, son, there might 747 00:39:25,030 --> 00:39:26,926 be something to what you say. 748 00:39:26,950 --> 00:39:29,836 But no one will listen to you unless you 749 00:39:29,860 --> 00:39:31,300 get your credentials. 750 00:39:42,820 --> 00:39:44,836 My personal background really has a lot 751 00:39:44,860 --> 00:39:49,886 to do with Timothy Leary and the use of psychedelics in society. 752 00:39:49,910 --> 00:39:53,246 I had been born Jewish in 1953. 753 00:39:53,270 --> 00:39:55,406 I was raised on stories of the Holocaust. 754 00:39:55,430 --> 00:39:57,596 And then, as a young boy, I was involved 755 00:39:57,620 --> 00:40:02,056 in going to school during the Cuban Missile Crisis. 756 00:40:02,080 --> 00:40:04,066 This idea that there could be nuclear war 757 00:40:04,090 --> 00:40:09,316 and wipe out civilization was also very traumatizing. 758 00:40:09,340 --> 00:40:11,146 The final step for me was Vietnam, 759 00:40:11,170 --> 00:40:13,636 and I was in the last years of the lottery. 760 00:40:13,660 --> 00:40:17,416 And I was a Vietnam War protester, a draft resister. 761 00:40:17,440 --> 00:40:20,716 And so I first tried LSD in '71, but I 762 00:40:20,740 --> 00:40:22,316 had a very difficult time. 763 00:40:22,340 --> 00:40:25,658 And I couldn't really handle my psychedelic experiences. 764 00:40:25,682 --> 00:40:27,616 I went to the guidance counselor at my college, 765 00:40:27,640 --> 00:40:29,146 and I was so lucky. 766 00:40:29,170 --> 00:40:31,006 The guidance counselor took me seriously. 767 00:40:31,030 --> 00:40:34,526 And then, he said that this was an important exploration 768 00:40:34,550 --> 00:40:35,327 that I was doing. 769 00:40:35,351 --> 00:40:37,246 And he gave me a book to read, which 770 00:40:37,270 --> 00:40:39,826 was a manuscript copy of "Realms of the Human 771 00:40:39,850 --> 00:40:44,026 Unconscious, Observations from LSD Research," by Stan Grof. 772 00:40:44,050 --> 00:40:46,586 When I read this book, everything fell into place 773 00:40:46,610 --> 00:40:47,387 for me. 774 00:40:47,411 --> 00:40:50,476 I saw this therapeutic use and also 775 00:40:50,500 --> 00:40:52,226 the spiritual aspects of it. 776 00:40:52,250 --> 00:40:54,556 And I felt, OK, this is a response 777 00:40:54,580 --> 00:40:57,986 to the craziness of the world. 778 00:40:58,010 --> 00:41:01,816 It seems to me that since the French Revolution 779 00:41:01,840 --> 00:41:05,056 and the Enlightenment, man was put at the center 780 00:41:05,080 --> 00:41:06,646 of the universe. 781 00:41:06,670 --> 00:41:10,516 And certain difficult notions of God, 782 00:41:10,540 --> 00:41:13,516 on which one was dependent, were put aside. 783 00:41:13,540 --> 00:41:17,086 And that notion of man being at the center of the universe 784 00:41:17,110 --> 00:41:19,996 led to the industrial society that we have around us, led 785 00:41:20,020 --> 00:41:22,216 to a great deal of energy. 786 00:41:22,240 --> 00:41:24,106 And the LSD experience and what we've 787 00:41:24,130 --> 00:41:27,076 been through in the '60s has brought us 788 00:41:27,100 --> 00:41:29,986 to a whole new philosophy, that man 789 00:41:30,010 --> 00:41:31,786 is not the center of the universe, 790 00:41:31,810 --> 00:41:34,711 that we're simply the transformative energies, 791 00:41:34,735 --> 00:41:37,126 and that we live in a sort of cosmic ecology 792 00:41:37,150 --> 00:41:39,856 for which we're responsible. 793 00:41:39,880 --> 00:41:43,726 And this is, to my mind, the great challenge that's 794 00:41:43,750 --> 00:41:47,776 in front of us, to take the consciousness 795 00:41:47,800 --> 00:41:50,986 and the individual headspace that we've all 796 00:41:51,010 --> 00:41:54,926 managed to develop and now begin asking ourselves, 797 00:41:54,950 --> 00:41:57,280 what is it all for, and how can we use it? 798 00:42:04,380 --> 00:42:07,376 We're now in what you can consider a second renaissance 799 00:42:07,400 --> 00:42:08,936 of psychedelic research. 800 00:42:08,960 --> 00:42:12,476 There are a handful of centers in the US, universities 801 00:42:12,500 --> 00:42:14,336 that are conducting research studies. 802 00:42:14,360 --> 00:42:18,146 Probably the reinitiation of psychedelic research, 803 00:42:18,170 --> 00:42:20,336 I would really credit Rick Strassmann. 804 00:42:20,360 --> 00:42:23,156 Rick Strassmann had been one of the doctors that I'd worked 805 00:42:23,180 --> 00:42:23,957 with. 806 00:42:23,981 --> 00:42:27,686 And he decided that he would submit a protocol for DMT, 807 00:42:27,710 --> 00:42:31,346 looking at it as potential cause of schizophrenia. 808 00:42:31,370 --> 00:42:35,846 A psychotomimetic model, so it means mimicking psychosis. 809 00:42:35,870 --> 00:42:38,186 And so it's a way for a government agency 810 00:42:38,210 --> 00:42:41,946 to feel OK about funding psychedelic research. 811 00:42:41,970 --> 00:42:45,296 So the Pilot Drug Evaluation Staff approved this study 812 00:42:45,320 --> 00:42:46,227 in 1990... 813 00:42:46,251 --> 00:42:48,986 and really kind of reinitiated the field, 814 00:42:49,010 --> 00:42:49,857 I would say. 815 00:42:49,881 --> 00:42:52,406 And then our work here, Roland Griffiths 816 00:42:52,430 --> 00:42:54,896 got it started not long after. 817 00:42:54,920 --> 00:42:58,976 In 2006, the Hopkins team set the standard for scientific 818 00:42:59,000 --> 00:43:02,606 rigor by publishing their landmark study "A followup 819 00:43:02,630 --> 00:43:05,576 to Walter Pahnke's and Timothy Leary's Good Friday 820 00:43:05,600 --> 00:43:08,966 experiment," concluding that under the right setting, 821 00:43:08,990 --> 00:43:12,926 psilocybin can reliably induce a mystical experience. 822 00:43:12,950 --> 00:43:15,506 I knew nothing about Johns Hopkins. 823 00:43:15,530 --> 00:43:17,304 I didn't know anything about Baltimore. 824 00:43:17,328 --> 00:43:18,596 I didn't know Roland Griffiths. 825 00:43:18,620 --> 00:43:20,186 I didn't know any of these characters. 826 00:43:20,210 --> 00:43:23,036 And I ended up going to grad school out in California where 827 00:43:23,060 --> 00:43:25,466 we were doing a study with meditators when 828 00:43:25,490 --> 00:43:28,946 Roland's paper was published on mystical experiences promoted 829 00:43:28,970 --> 00:43:30,086 by psilocybin. 830 00:43:30,110 --> 00:43:31,886 And I just remember saying to my advisor, 831 00:43:31,910 --> 00:43:33,553 I was like, that's where I'm going next. 832 00:43:33,577 --> 00:43:35,666 Katherine MacLean's research on openness, 833 00:43:35,690 --> 00:43:39,146 that was a really big deal, that study, because it was always 834 00:43:39,170 --> 00:43:42,266 thought that your personality is your personality. 835 00:43:42,290 --> 00:43:44,666 How novelty-seeking you are and how open you are, 836 00:43:44,690 --> 00:43:46,916 that's just who you are, and those things don't really 837 00:43:46,940 --> 00:43:47,717 change. 838 00:43:47,741 --> 00:43:50,306 But what the Hopkins trials showed 839 00:43:50,330 --> 00:43:51,956 was that people do become more open, 840 00:43:51,980 --> 00:43:54,206 and you can actually measure it on a personality test. 841 00:43:54,230 --> 00:43:55,286 And that's a big deal. 842 00:43:55,310 --> 00:43:59,666 70% of people were saying, this is among the five most 843 00:43:59,690 --> 00:44:03,066 personally meaningful experiences of my life. 844 00:44:03,090 --> 00:44:05,426 I would ask people, what does that mean? 845 00:44:05,450 --> 00:44:08,066 And someone might say, well, gee, 846 00:44:08,090 --> 00:44:11,576 when my first child was born, my daughter, that 847 00:44:11,600 --> 00:44:14,256 changed my life forever. 848 00:44:14,280 --> 00:44:17,576 And recently, my father passed away. 849 00:44:17,600 --> 00:44:19,396 That was big. 850 00:44:19,420 --> 00:44:20,495 It's kind of like that. 851 00:44:25,790 --> 00:44:29,446 It was around 2006, and I had just taken over as the head 852 00:44:29,470 --> 00:44:31,821 of the Division of Alcoholism and Drug Abuse at Bellevue. 853 00:44:31,845 --> 00:44:33,956 As an addiction psychiatrist, I'd 854 00:44:33,980 --> 00:44:35,996 always been interested in these compounds 855 00:44:36,020 --> 00:44:38,966 because they just seem different from other drugs of abuse. 856 00:44:38,990 --> 00:44:41,941 They didn't behave like cocaine or amphetamine or tobacco. 857 00:44:41,965 --> 00:44:43,316 They seemed completely different, 858 00:44:43,340 --> 00:44:45,656 yet they were labeled as the most addictive drug. 859 00:44:45,680 --> 00:44:47,336 So I always thought that there was 860 00:44:47,360 --> 00:44:49,346 something interesting and different about them. 861 00:44:49,370 --> 00:44:51,026 At the time, one of my supervisors 862 00:44:51,050 --> 00:44:52,616 was Dr. Jeffrey Guss. 863 00:44:52,640 --> 00:44:57,026 I saw that Albert Hofmann's 100th birthday was being 864 00:44:57,050 --> 00:45:00,146 celebrated in Basel, Switzerland. 865 00:45:00,170 --> 00:45:04,016 I must do what Huxley wrote me in a letter. 866 00:45:04,040 --> 00:45:06,516 What you take in by vision experience 867 00:45:06,540 --> 00:45:09,446 you must give out in daily life. 868 00:45:09,470 --> 00:45:13,036 And that is now the task which I try, 869 00:45:13,060 --> 00:45:17,816 the feeling to be a part of the universe, which 870 00:45:17,840 --> 00:45:20,556 I got by LSD experience. 871 00:45:20,580 --> 00:45:25,134 This feeling is always present in my life. 872 00:45:25,158 --> 00:45:27,176 When you think about what people thought about 873 00:45:27,200 --> 00:45:30,356 in the '60s, that LSD is going to make you drop out 874 00:45:30,380 --> 00:45:32,906 of society, Albert Hofmann, who discovered LSD, 875 00:45:32,930 --> 00:45:36,596 was married for 79 years, had a career at the same company 876 00:45:36,620 --> 00:45:41,516 for almost his entire life, and was an inspiration to quite 877 00:45:41,540 --> 00:45:43,136 a few of us. 878 00:45:43,160 --> 00:45:46,586 Sort of on a lark, I went to this conference because I 879 00:45:46,610 --> 00:45:49,076 wanted to meet and see the people that were doing 880 00:45:49,100 --> 00:45:50,276 psychedelic research. 881 00:45:50,300 --> 00:45:53,666 And it was there that I first met Charles Grob. 882 00:45:53,690 --> 00:45:58,376 Administering a psychedelic to cancer patient with anxiety 883 00:45:58,400 --> 00:46:01,976 had not occurred since the early 1970s. 884 00:46:02,000 --> 00:46:04,796 And I felt this was an ideal patient population 885 00:46:04,820 --> 00:46:07,976 to really start off with because the early literature was 886 00:46:08,000 --> 00:46:09,156 so impressive. 887 00:46:09,180 --> 00:46:12,206 And all of this, from FDA through the hospital 888 00:46:12,230 --> 00:46:14,456 committees, took several years. 889 00:46:14,480 --> 00:46:17,576 But I was patient, and I was persistent, 890 00:46:17,600 --> 00:46:21,566 and I felt this was really a worthy effort to make. 891 00:46:21,590 --> 00:46:24,956 And in the end, we got the approvals we had requested. 892 00:46:24,980 --> 00:46:27,686 When I was at NYU, I was working at Bellevue for nine 893 00:46:27,710 --> 00:46:30,116 years, running the psychiatric emergency room. 894 00:46:30,140 --> 00:46:32,756 I met with the chairman at the time, a guy named Robert 895 00:46:32,780 --> 00:46:35,216 Cancro, And I talked to him a lot 896 00:46:35,240 --> 00:46:38,726 about what was going on at UCLA or at Hopkins 897 00:46:38,750 --> 00:46:41,126 and saying that there was really enough people at NYU who 898 00:46:41,150 --> 00:46:43,826 are interested that we should try to do something in NYU. 899 00:46:43,850 --> 00:46:47,096 In the 1970s, I came across the literature on psychedelics 900 00:46:47,120 --> 00:46:49,638 and entheogens, and I also have a long interest in palliative 901 00:46:49,662 --> 00:46:50,439 care... 902 00:46:50,463 --> 00:46:51,986 I'm a palliative care psychologist... 903 00:46:52,010 --> 00:46:55,526 And how we die in this country and the death anxiety. 904 00:46:55,550 --> 00:46:57,761 And it felt the perfect match. 905 00:46:57,785 --> 00:46:59,636 At first, we were just an education group. 906 00:46:59,660 --> 00:47:03,156 But after meeting Charlie Grob at UCLA, I asked him, 907 00:47:03,180 --> 00:47:05,456 so this is really possible to do this, 908 00:47:05,480 --> 00:47:07,986 and you can make a career out of this? 909 00:47:08,010 --> 00:47:10,196 And he said, yes, and it's all about doing it 910 00:47:10,220 --> 00:47:12,266 correctly and carefully and avoiding 911 00:47:12,290 --> 00:47:14,136 mistakes made in the past. 912 00:47:14,160 --> 00:47:15,920 So we decided to do it. 913 00:47:23,560 --> 00:47:26,766 My name is Estalyn Walcoff, and I work 914 00:47:26,790 --> 00:47:28,026 as a psychotherapist. 915 00:47:28,050 --> 00:47:29,886 My name is Dinah Bazer. 916 00:47:29,910 --> 00:47:31,566 I teach figure skating. 917 00:47:31,590 --> 00:47:35,226 My name is Nick Fernandez, and I work as a clinical 918 00:47:35,250 --> 00:47:37,626 research coordinator in a psychiatry department 919 00:47:37,650 --> 00:47:39,316 at a hospital here in New York. 920 00:47:39,340 --> 00:47:42,486 I'm an adult literacy teacher, 921 00:47:42,510 --> 00:47:44,926 part-time at the public library. 922 00:47:44,950 --> 00:47:51,186 I was diagnosed five years ago with a type of lymphoma 923 00:47:51,210 --> 00:47:52,776 that was untreatable. 924 00:47:52,800 --> 00:47:56,796 And not only was it untreatable, but everybody who had had it 925 00:47:56,820 --> 00:47:58,086 had died from it. 926 00:47:58,110 --> 00:47:59,596 It was aggressive. 927 00:47:59,620 --> 00:48:03,636 I was diagnosed with leukemia when I was 17 in 2004. 928 00:48:03,660 --> 00:48:06,396 And it was during my senior year of high school 929 00:48:06,420 --> 00:48:08,856 when I was just getting ready to go to college. 930 00:48:08,880 --> 00:48:12,816 I received the official diagnosis in December of last 931 00:48:12,840 --> 00:48:15,246 year, so just about a year ago. 932 00:48:15,270 --> 00:48:18,096 And it changed the course of my life, 933 00:48:18,120 --> 00:48:23,196 because I went from being a physically active 17-year-old 934 00:48:23,220 --> 00:48:25,026 to a cancer patient. 935 00:48:25,050 --> 00:48:28,446 When the chemo was over, I thought, let's celebrate. 936 00:48:28,470 --> 00:48:29,946 I thought I would want to celebrate. 937 00:48:29,970 --> 00:48:32,279 And when the chemo was over, I didn't want to celebrate, 938 00:48:32,303 --> 00:48:35,946 because that's when the fear set in. 939 00:48:35,970 --> 00:48:39,096 That's when you start thinking, when will the other shoe drop? 940 00:48:39,120 --> 00:48:41,436 When will this come back? 941 00:48:41,460 --> 00:48:44,166 Always in my life, I've been an anxious person. 942 00:48:44,190 --> 00:48:47,766 And naturally, when I was given that diagnosis 943 00:48:47,790 --> 00:48:49,116 my anxiety shot up. 944 00:48:49,140 --> 00:48:53,616 And even though years and years and years keep going by 945 00:48:53,640 --> 00:48:56,916 and I'm still OK, I know very well 946 00:48:56,940 --> 00:49:00,616 that this could return at any moment. 947 00:49:00,640 --> 00:49:04,366 I really went to work on myself because I thought that 948 00:49:04,390 --> 00:49:07,756 if I were going to die much sooner than I had planned, 949 00:49:07,780 --> 00:49:10,966 then I wanted to understand myself better. 950 00:49:10,990 --> 00:49:13,606 I wanted to understand spirituality better. 951 00:49:13,630 --> 00:49:17,146 I wanted not to have a bitter heart. 952 00:49:17,170 --> 00:49:20,126 And I wanted to be open. 953 00:49:20,150 --> 00:49:24,526 So I did what I could for the past five years. 954 00:49:24,550 --> 00:49:27,946 And I came across a post about this study. 955 00:49:27,970 --> 00:49:29,656 I read it once, and then I closed it. 956 00:49:29,680 --> 00:49:32,515 And then I read it again, and I said, I qualify for that. 957 00:49:35,060 --> 00:49:39,706 So I traveled down to New York City for an initial screening 958 00:49:39,730 --> 00:49:40,607 interview. 959 00:49:40,631 --> 00:49:43,306 I traveled down to New York City several times 960 00:49:43,330 --> 00:49:47,326 for psychotherapy sessions with my two psychiatrists. 961 00:49:47,350 --> 00:49:49,816 After several sessions of therapy and careful 962 00:49:49,840 --> 00:49:52,816 preparation, participants are given psilocybin 963 00:49:52,840 --> 00:49:55,576 in a comfortable living room setting under the guidance 964 00:49:55,600 --> 00:49:57,776 of their therapist team. 965 00:49:57,800 --> 00:50:00,056 After a brief ritual, they are encouraged 966 00:50:00,080 --> 00:50:03,266 to lie down on the couch, wear eye shades, 967 00:50:03,290 --> 00:50:05,576 and listen to classical music in order 968 00:50:05,600 --> 00:50:07,916 to create an inward experience. 969 00:50:07,940 --> 00:50:12,566 Having mentioned that I had taken psychedelics in my 20s, 970 00:50:12,590 --> 00:50:15,446 the whole object was to see how beautiful nature was, 971 00:50:15,470 --> 00:50:19,204 to hear how wonderful music was, to see what could be seen, 972 00:50:19,228 --> 00:50:20,496 to touch what could be touched. 973 00:50:20,520 --> 00:50:23,516 So this was very, very different because the whole thing 974 00:50:23,540 --> 00:50:25,850 that I was going to be experiencing was my own mind. 975 00:50:36,690 --> 00:50:40,026 There was an immersion into complete chaos, 976 00:50:40,050 --> 00:50:45,306 360-degree chaos, where I had no idea of up, down, left, right. 977 00:50:45,330 --> 00:50:48,786 Initially, it was absolutely terrifying. 978 00:50:48,810 --> 00:50:50,346 I think I could compare it to being 979 00:50:50,370 --> 00:50:54,075 in the hold of a ship that's in a storm-tossed sea. 980 00:50:56,640 --> 00:51:01,726 I also began experiencing great emotional pain, 981 00:51:01,750 --> 00:51:06,336 in particular because I had been listening to a Black spiritual. 982 00:51:06,360 --> 00:51:10,934 I felt I could hear the pain in that woman's voice 983 00:51:10,958 --> 00:51:11,976 who was singing the song. 984 00:51:12,000 --> 00:51:16,026 And it brought to me the whole gestalt of slavery 985 00:51:16,050 --> 00:51:19,386 and what that is to pull people out of their homes 986 00:51:19,410 --> 00:51:20,826 and treat them like animals. 987 00:51:20,850 --> 00:51:26,571 And I sobbed and sobbed and sobbed because of that. 988 00:51:32,570 --> 00:51:37,316 And the ability to just be held by my mentors 989 00:51:37,340 --> 00:51:41,556 and do that greatly, greatly relieved me. 990 00:51:41,580 --> 00:51:45,386 And I believe it was Tony who took my hand and said, 991 00:51:45,410 --> 00:51:46,616 it's all right. 992 00:51:46,640 --> 00:51:47,427 It's all right. 993 00:51:47,451 --> 00:51:49,026 Just go with it. 994 00:51:49,050 --> 00:51:51,966 And the further I went into it, 995 00:51:51,990 --> 00:51:57,176 the more it became evident to me that the chaos could not 996 00:51:57,200 --> 00:52:05,200 maintain its magnetic draw on me nor its strength when I stayed 997 00:52:07,020 --> 00:52:08,020 focused. 998 00:52:13,330 --> 00:52:17,236 The worst pain and the worst fear and the worst anxiety 999 00:52:17,260 --> 00:52:21,086 turned into something that has opened, 1000 00:52:21,110 --> 00:52:25,576 which is the most precious thing I've ever known. 1001 00:52:25,600 --> 00:52:31,966 It was a sense of connectedness that runs through all of us 1002 00:52:31,990 --> 00:52:37,126 that I never knew, and also a sense of the strength of it 1003 00:52:37,150 --> 00:52:38,440 and the power of it. 1004 00:52:41,360 --> 00:52:45,746 It looked like very dense and beautiful clouds that were 1005 00:52:45,770 --> 00:52:50,036 almost like in the jigsaw puzzle fashion that were backlit 1006 00:52:50,060 --> 00:52:51,806 by a moon that I could not see. 1007 00:52:51,830 --> 00:52:55,616 So they were crevices of faint light through it. 1008 00:52:55,640 --> 00:52:59,796 And these eyes were searching me out. 1009 00:52:59,820 --> 00:53:06,486 I felt it was a manifestation of an alienation I had long 1010 00:53:06,510 --> 00:53:08,526 carried through my whole life that was just 1011 00:53:08,550 --> 00:53:10,350 trying to lay claim to me. 1012 00:53:16,760 --> 00:53:21,076 I felt very profoundly that there was no one 1013 00:53:21,100 --> 00:53:24,386 that they could find. 1014 00:53:24,410 --> 00:53:25,540 I saw my fear. 1015 00:53:29,670 --> 00:53:31,026 I pictured it. 1016 00:53:31,050 --> 00:53:35,116 I don't think this was a hallucination. 1017 00:53:35,140 --> 00:53:38,686 I pictured it as a dark mass there. 1018 00:53:38,710 --> 00:53:42,346 I, like, screamed, "Get the fuck out!" 1019 00:53:42,370 --> 00:53:45,736 I will not be eaten alive by this fear. 1020 00:53:45,760 --> 00:53:49,966 And once that happened, it was just gone. 1021 00:53:49,990 --> 00:53:55,266 The fear was gone and didn't come back. 1022 00:53:55,290 --> 00:53:57,366 And it still hasn't. 1023 00:53:57,390 --> 00:54:01,386 I had this feeling coming over me, 1024 00:54:01,410 --> 00:54:05,880 and the thought was of compassion for myself. 1025 00:54:10,790 --> 00:54:12,205 It touches me the most. 1026 00:54:14,710 --> 00:54:17,746 That's such a gift. 1027 00:54:17,770 --> 00:54:25,770 I needed to stop talking and look inside and find that I was 1028 00:54:26,870 --> 00:54:27,647 part of it. 1029 00:54:27,671 --> 00:54:28,688 I was part of everything. 1030 00:54:28,712 --> 00:54:33,246 I was part of God, that you are, too. 1031 00:54:33,270 --> 00:54:34,266 Everything is. 1032 00:54:34,290 --> 00:54:36,336 And you can call it whatever you want to. 1033 00:54:36,360 --> 00:54:37,806 I don't usually call it God. 1034 00:54:37,830 --> 00:54:38,925 I just call it the one. 1035 00:54:44,360 --> 00:54:47,420 And that's the best thing that can ever happen to you, ever. 1036 00:54:51,730 --> 00:54:56,206 We co-evolved on the planet with cannabis and with poppy 1037 00:54:56,230 --> 00:54:58,366 and psilocybin mushrooms. 1038 00:54:58,390 --> 00:55:00,916 These things have been on the planet since we have, 1039 00:55:00,940 --> 00:55:02,386 as far as I can tell, which means 1040 00:55:02,410 --> 00:55:04,576 we've co-evolved with them. 1041 00:55:04,600 --> 00:55:06,136 And psychiatry is kind of failing. 1042 00:55:06,160 --> 00:55:08,356 Many, many people are taking sleeping pills 1043 00:55:08,380 --> 00:55:10,606 and anti-anxiety meds and antidepressants 1044 00:55:10,630 --> 00:55:13,736 and for a really long time. 1045 00:55:13,760 --> 00:55:16,306 I really think there's a better way to treat addiction 1046 00:55:16,330 --> 00:55:21,886 or to treat the sort of despair and anxiety and malaise 1047 00:55:21,910 --> 00:55:24,145 that many of us are feeling more and more. 1048 00:55:27,070 --> 00:55:28,966 We need a different perspective, and we 1049 00:55:28,990 --> 00:55:31,096 need that sort of overview effect 1050 00:55:31,120 --> 00:55:35,086 that the astronauts get when they see that every one of us 1051 00:55:35,110 --> 00:55:38,110 is just on this blue ball hurtling through space. 1052 00:55:41,110 --> 00:55:43,466 I think that psychedelics give you that perspective. 1053 00:55:43,490 --> 00:55:47,116 And so I hope that they can engender more cooperation, 1054 00:55:47,140 --> 00:55:50,866 more us versus them, more of this idea 1055 00:55:50,890 --> 00:55:54,516 that separation is an illusion, and that we all sort of 1056 00:55:54,540 --> 00:55:57,276 have the answers for our own growth 1057 00:55:57,300 --> 00:55:59,325 and for the healing of the planet. 1058 00:56:03,000 --> 00:56:06,906 If people could know how connected they really are, 1059 00:56:06,930 --> 00:56:09,666 connected to spirit and connected to each other 1060 00:56:09,690 --> 00:56:13,566 and connected to nature, so much of their fear would dissipate. 1061 00:56:13,590 --> 00:56:15,786 So much of their anxiety would dissipate. 1062 00:56:15,810 --> 00:56:19,146 And I just know that if, in the future, 1063 00:56:19,170 --> 00:56:24,336 this could be used with all patients, 1064 00:56:24,360 --> 00:56:28,896 under the direction of mentors, shamans, psychotherapists, 1065 00:56:28,920 --> 00:56:31,965 it would make for a much happier world. 82046

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