All language subtitles for Silent Witness - 24x06 - Reputations, Part 2.AMZN.NTb.English.C.updated.Addic7ed.com

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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:06,250 --> 00:00:11,400 Victim is Mr Arnie Rahul. Consultant surgeon. 48 years of age. 2 00:00:11,500 --> 00:00:14,535 Good reputation, though he's fallen out with a few people recently. 3 00:00:14,560 --> 00:00:17,175 He was about to start an operation. He gets a phone call. 4 00:00:17,200 --> 00:00:19,439 Walks out, never comes back. 5 00:00:19,440 --> 00:00:22,100 Single puncture wound to the left chest wall. 6 00:00:23,560 --> 00:00:26,359 - What's that in his hand? - Looks like a syringe and needle. 7 00:00:26,360 --> 00:00:29,599 It's a Hickman line. A long-term vascular access device 8 00:00:29,600 --> 00:00:32,119 for people who need chemotherapy or blood transfusions. 9 00:00:32,120 --> 00:00:34,839 The assailant would have had extensive cross contamination 10 00:00:34,840 --> 00:00:36,319 with the victim's blood. 11 00:00:36,320 --> 00:00:38,479 Stick that in to a big artery and blood will flow out 12 00:00:38,480 --> 00:00:40,039 like a high-pressure hose. 13 00:00:40,040 --> 00:00:41,640 Simi Jacobs. 14 00:00:42,480 --> 00:00:43,840 He's denying everything. 15 00:00:44,920 --> 00:00:48,159 Simi Jacobs is not a match 16 00:00:48,160 --> 00:00:49,799 to the blood spatter at the scene. 17 00:00:49,800 --> 00:00:52,079 So, who is it? It's Wilfred Okoye. 18 00:00:52,080 --> 00:00:53,199 The patient? 19 00:00:53,200 --> 00:00:56,959 Arnie Rahul was murdered by a man who was under general anaesthetic 20 00:00:56,960 --> 00:00:58,359 in a different room? 21 00:00:58,360 --> 00:01:01,999 Blood alcohol level, three times the legal driving limit. 22 00:01:02,000 --> 00:01:04,319 You said he shouldn't be operating. 23 00:01:04,320 --> 00:01:06,319 Not after the Harry Fletcher incident. 24 00:01:06,320 --> 00:01:09,239 Arrested on the table during surgery last week. 25 00:01:09,240 --> 00:01:11,879 I want you to do the postmortem. 26 00:01:11,880 --> 00:01:14,079 Technically that would be a conflict of interest. 27 00:01:14,080 --> 00:01:17,359 Summarising postmortem examination, Harry Fletcher. 28 00:01:17,360 --> 00:01:19,279 What are you doing? My colleagues are here. 29 00:01:19,280 --> 00:01:22,239 - Is that Emily Braithwaite? - She's Adam's godmother. 30 00:01:22,240 --> 00:01:24,359 You'd think he might have mentioned it. 31 00:01:24,360 --> 00:01:26,879 - Are you going to confront him? - Not yet. 32 00:01:26,880 --> 00:01:29,319 Your original stem cell work was brilliant. 33 00:01:29,320 --> 00:01:33,199 But you tried and failed to turn it into a viable cancer treatment. 34 00:01:33,200 --> 00:01:35,759 Wilfred Okoye, still in the hospital. 35 00:01:35,760 --> 00:01:37,439 What's he going to know? 36 00:01:37,440 --> 00:01:40,399 You won't find out unless you ask him. 37 00:01:40,400 --> 00:01:43,279 Mr Fletcher died because of surgical error. 38 00:01:43,280 --> 00:01:46,839 Adam! You have no idea what you've done. 39 00:01:46,840 --> 00:01:49,359 When I applied for this job I falsified my CV, 40 00:01:49,360 --> 00:01:51,239 and Emily Braithwaite tried to use this 41 00:01:51,240 --> 00:01:53,519 fact to influence my findings in the Fletcher Case. 42 00:01:53,520 --> 00:01:55,199 Here's my letter of resignation. 43 00:01:55,200 --> 00:01:56,480 Effective immediately. 44 00:02:45,815 --> 00:02:49,735 Wilfred Okoye, a Beninese farm worker, was admitted 45 00:02:49,760 --> 00:02:53,559 to St Jude's hospital for the treatment of leukaemia a week ago. 46 00:02:53,560 --> 00:02:57,135 Although he lost consciousness briefly during the attack 47 00:02:57,160 --> 00:03:00,839 on his life last night, he seems to have recovered with no ill effects. 48 00:03:00,840 --> 00:03:05,159 Awaiting toxicology from the syringe we believe was used in the attack. 49 00:03:05,160 --> 00:03:06,559 Prints? Fibres? 50 00:03:06,560 --> 00:03:09,199 - Nothing conclusive. - We're interviewing witnesses 51 00:03:09,200 --> 00:03:11,159 but no-one got a good look at the attacker. 52 00:03:11,160 --> 00:03:13,679 How come he's being treated here in the UK? 53 00:03:13,680 --> 00:03:17,520 It was set up by a charity, and then arranged through Rahul. 54 00:03:19,120 --> 00:03:23,575 Here is a man who has lived his entire life in Benin 55 00:03:23,600 --> 00:03:27,639 up until a week ago, and, according to our DNA evidence, 56 00:03:27,640 --> 00:03:31,920 murders his surgeon while under anaesthetic in a different room. 57 00:03:35,162 --> 00:03:41,119 Could the DNA at the murder scene been a contaminant or planted? 58 00:03:41,120 --> 00:03:43,599 No. The spatter patterns are too perfect. 59 00:03:43,600 --> 00:03:46,239 It came from someone who was in the room at the time. 60 00:03:46,240 --> 00:03:47,880 So, how do you explain it? 61 00:03:51,200 --> 00:03:54,279 How do we know Wilfred was anaesthetised? 62 00:03:54,280 --> 00:03:56,959 I mean, how do we know it was him? 63 00:03:56,960 --> 00:03:58,719 What, he's got an identical twin? 64 00:03:58,720 --> 00:04:00,199 Bit fantastical, Steve. 65 00:04:00,200 --> 00:04:01,400 I don't know. 66 00:04:02,040 --> 00:04:03,640 There's another explanation. 67 00:04:05,556 --> 00:04:07,676 DNA samples got mixed up. 68 00:04:07,815 --> 00:04:09,599 Ah! No way! 69 00:04:09,600 --> 00:04:11,480 Look, I'm just putting it out there. 70 00:04:11,504 --> 00:04:13,016 - Mm-mn. - We could run the test again. 71 00:04:13,040 --> 00:04:15,040 Those samples were handled correctly. 72 00:04:16,480 --> 00:04:18,778 Jack, shall we just run them again? 73 00:04:21,960 --> 00:04:23,720 Right, yep. Good. 74 00:04:24,960 --> 00:04:26,000 OK. 75 00:04:26,989 --> 00:04:29,120 Let me know when toxicology comes back. 76 00:04:37,167 --> 00:04:40,240 So, the samples got mixed up, 77 00:04:40,264 --> 00:04:41,511 - did they? - It's always possible. 78 00:04:41,536 --> 00:04:42,576 Mm-hm. 79 00:04:42,811 --> 00:04:46,433 You know who took the swab from Simi Jacobs. Adam. 80 00:04:47,449 --> 00:04:48,960 What are you suggesting? 81 00:04:50,851 --> 00:04:52,331 Just saying. 82 00:05:01,240 --> 00:05:03,039 You have reached Dr Adam Yuen. 83 00:05:03,040 --> 00:05:04,639 I am unable to take your call. 84 00:05:04,640 --> 00:05:06,600 Please leave a message after the tone. 85 00:05:09,400 --> 00:05:11,440 Do you know what I don't understand? 86 00:05:11,780 --> 00:05:14,159 It was just a six-month placement, 87 00:05:14,160 --> 00:05:16,799 and his CV is impressive enough without it. 88 00:05:16,800 --> 00:05:19,960 So, why did he risk his career and lie about it? 89 00:05:22,673 --> 00:05:24,700 Has he lied about anything else? 90 00:05:24,993 --> 00:05:26,980 Everything else checks out. 91 00:05:27,513 --> 00:05:28,993 Are you sure about that? 92 00:05:32,433 --> 00:05:36,726 You have an injury over your left eye and a wound on your neck. 93 00:05:37,593 --> 00:05:40,040 How do you account for them, Simi? 94 00:05:40,793 --> 00:05:42,272 Yeah, I got mugged. 95 00:05:42,273 --> 00:05:44,713 - A kid with a knife. - Really? 96 00:05:46,012 --> 00:05:48,292 And did you report the assault? 97 00:05:48,753 --> 00:05:50,920 - No. - Why not? 98 00:05:51,313 --> 00:05:53,220 What, are you going to catch him? 99 00:05:55,073 --> 00:05:58,393 He's answered your questions, so unless you have other evidence? 100 00:06:21,633 --> 00:06:25,255 Tox results from the syringe used in the attack on Wilfred. 101 00:06:25,280 --> 00:06:27,040 - Here we go. - Let's have a look. 102 00:06:32,160 --> 00:06:34,520 - That's it? - Midazolam? 103 00:06:36,350 --> 00:06:38,550 That's a sedative, isn't it? 104 00:06:38,800 --> 00:06:39,840 Yeah. 105 00:06:41,648 --> 00:06:45,728 The full syringe would have had about five milligrams in it. 106 00:06:46,080 --> 00:06:47,380 That's not very much. 107 00:06:48,240 --> 00:06:52,319 So, either the assailant is incompetent, 108 00:06:52,320 --> 00:06:54,900 or this wasn't intended to kill him. 109 00:06:55,940 --> 00:06:57,700 So, what's the aim? 110 00:06:59,000 --> 00:07:00,340 Kidnapping? 111 00:07:05,300 --> 00:07:07,020 The guy's already ill. 112 00:07:07,600 --> 00:07:09,240 You know... 113 00:07:09,500 --> 00:07:13,420 If someone wanted him dead, it's not going to be that hard, is it? 114 00:07:13,880 --> 00:07:15,200 He's got leukaemia. 115 00:07:16,711 --> 00:07:20,020 It would look like natural causes if he died of sepsis. 116 00:07:22,219 --> 00:07:25,460 Should I get that syringe tested again for bacteria? 117 00:07:31,952 --> 00:07:34,479 What's this about Mr Okoye being moved? 118 00:07:34,480 --> 00:07:35,999 It's for his own safety. 119 00:07:36,000 --> 00:07:39,215 To the Cowley Institute? And who's paying for that? 120 00:07:39,240 --> 00:07:41,839 Oh, I've been assured that they have all the facilities required, 121 00:07:41,840 --> 00:07:44,100 and they've offered to do the treatment free of charge. 122 00:07:44,420 --> 00:07:45,919 I will not allow it. 123 00:07:45,920 --> 00:07:49,600 Someone in your hospital is trying to kill Mr Okoye. 124 00:07:50,393 --> 00:07:53,553 Quite frankly, Dr Braithwaite, I don't need your permission. 125 00:08:06,294 --> 00:08:07,820 Haematology lab. 126 00:08:09,020 --> 00:08:10,700 Dr Braithwaite here. 127 00:08:11,060 --> 00:08:15,959 Wilfred Okoye, hospital number 1187266. 128 00:08:15,960 --> 00:08:18,879 I want all his stored blood and marrow samples sent 129 00:08:18,880 --> 00:08:20,520 to my office immediately. 130 00:08:47,160 --> 00:08:48,420 Finished! 131 00:08:48,940 --> 00:08:54,460 79 needles swabbed and ready to go. 132 00:08:55,600 --> 00:08:57,340 You've got to see this. 133 00:08:57,960 --> 00:09:00,335 Microbiology results from the syringe 134 00:09:00,360 --> 00:09:02,280 used in the attack on Wilfred. 135 00:09:02,340 --> 00:09:05,580 Turns out it is full of bacteria - E coli. 136 00:09:07,340 --> 00:09:09,615 Well, it was lying around on the floor. 137 00:09:09,640 --> 00:09:10,679 Could it be a contaminant? 138 00:09:10,680 --> 00:09:13,439 No. It's a pure growth - just one type of bug in there. 139 00:09:13,440 --> 00:09:15,479 If it was a contaminant you'd expect to see 140 00:09:15,480 --> 00:09:16,999 lots of different organisms. 141 00:09:17,000 --> 00:09:18,880 It's been created deliberately. 142 00:09:19,628 --> 00:09:23,519 So, what? The killer sneaks into Wilfred's room pretending 143 00:09:23,520 --> 00:09:27,279 to be a nurse, inoculates him with the bacteria, 144 00:09:27,280 --> 00:09:29,100 but adds a mild sedative... 145 00:09:30,548 --> 00:09:33,599 ..so that when the real nurse comes in with his medication, 146 00:09:33,600 --> 00:09:37,460 he's asleep and can't tell her that someone else has already been in. 147 00:09:38,300 --> 00:09:40,359 He gets sepsis, he dies. 148 00:09:40,360 --> 00:09:41,900 Looks like natural causes. 149 00:09:43,180 --> 00:09:44,879 I need to tell DI Cracknell. 150 00:09:44,880 --> 00:09:47,720 You need to tell the doctors looking after Wilfred. 151 00:10:40,678 --> 00:10:43,919 It's as we expected - extensive peripheral oedema, 152 00:10:43,920 --> 00:10:46,959 multiple organ failure, consistent with sepsis. 153 00:10:46,960 --> 00:10:51,239 Yep. Toxicology shows only medications used for his treatment, 154 00:10:51,240 --> 00:10:54,719 antibiotics, ceftriaxone, gentamicin present 155 00:10:54,720 --> 00:10:56,439 in therapeutic concentrations. 156 00:10:56,440 --> 00:10:59,799 So, cause of death is consistent with deliberate inoculation 157 00:10:59,800 --> 00:11:02,679 of the culture of E coli, on a background 158 00:11:02,680 --> 00:11:05,879 of chemotherapy-induced immune compromise. 159 00:11:05,880 --> 00:11:08,999 Well, we've got no other leads on his attacker at present. 160 00:11:09,000 --> 00:11:11,399 We're liaising with the Beninese Consulate to inform 161 00:11:11,400 --> 00:11:13,260 the family of the deceased. 162 00:11:14,000 --> 00:11:19,020 DNA says Wilfred Okoye was guilty of Rahul's murder, 163 00:11:19,360 --> 00:11:22,009 but being unconscious, had the perfect alibi. 164 00:11:23,400 --> 00:11:26,399 When a murder suspect gets murdered, what does that mean? 165 00:11:26,400 --> 00:11:28,119 Framed by the real murderer? 166 00:11:28,120 --> 00:11:30,720 Why would you frame someone with the perfect alibi? 167 00:11:36,654 --> 00:11:38,380 Simi Jacobs. 168 00:11:38,940 --> 00:11:40,460 What's his home address? 169 00:11:40,800 --> 00:11:41,840 Erm... 170 00:11:43,517 --> 00:11:47,190 Let's see. Flat 32, Bardwell House, Lincoln Street. 171 00:11:47,440 --> 00:11:51,079 Thought so. Okoye and Jacobs have been living together. 172 00:11:51,080 --> 00:11:54,279 Simi Jacobs has already been released, guv. 173 00:11:54,280 --> 00:11:56,879 - What? - Yeah. Lack of forensics. 174 00:11:56,880 --> 00:11:58,079 All right. 175 00:11:58,080 --> 00:12:00,360 Might I suggest we pick him up again? 176 00:12:07,285 --> 00:12:09,365 It still doesn't get us anywhere. 177 00:12:09,451 --> 00:12:11,211 It doesn't explain the DNA. 178 00:12:11,236 --> 00:12:13,895 And Simi was in custody when Wilfred was attacked, 179 00:12:13,920 --> 00:12:15,319 so it doesn't even explain that. 180 00:12:15,320 --> 00:12:17,800 - We're just going round in circles. - Yep. 181 00:12:28,278 --> 00:12:31,839 When he was interviewed, Wilfred said his leukaemia 182 00:12:31,840 --> 00:12:34,760 was common in his region. 183 00:12:36,820 --> 00:12:38,520 Doesn't sound right to me. 184 00:12:55,360 --> 00:12:57,399 You have reached Dr Adam Yuen. 185 00:12:57,400 --> 00:12:58,839 I am unable to take your call. 186 00:12:58,840 --> 00:13:00,800 Please leave a message after the tone. 187 00:13:03,720 --> 00:13:05,679 Wait there. He's not in, guv. 188 00:13:05,680 --> 00:13:06,959 And the neighbours haven't seen him. 189 00:13:06,960 --> 00:13:09,400 He's not been seen back at work at the hospital either. 190 00:13:09,546 --> 00:13:12,160 You two stick around in case he comes back. 191 00:13:12,220 --> 00:13:15,780 I'm sorry, guv. I should have spotted the address. 192 00:13:17,340 --> 00:13:18,820 Don't worry about it. 193 00:13:19,300 --> 00:13:22,340 At least you didn't wrongly arrest a bereaved cancer patient. 194 00:13:26,743 --> 00:13:28,263 I'll do that next time. 195 00:13:32,426 --> 00:13:33,466 Bye. 196 00:13:38,520 --> 00:13:40,760 Nine missed calls. You're very persistent. 197 00:13:43,760 --> 00:13:45,580 I didn't want to end it like that. 198 00:13:48,040 --> 00:13:49,340 Can I help? 199 00:14:00,720 --> 00:14:03,759 You should have told me that Emily Braithwaite is your godmother. 200 00:14:03,760 --> 00:14:05,420 Some godmother. 201 00:14:05,680 --> 00:14:08,279 No doubt you've received the incriminating evidence about me. 202 00:14:08,280 --> 00:14:09,480 What evidence? 203 00:14:11,120 --> 00:14:14,215 She never sent it. I should have guessed. 204 00:14:14,240 --> 00:14:17,399 If she tried to blackmail you, then we'll make her answer for that. 205 00:14:17,400 --> 00:14:18,780 She's far too clever. 206 00:14:20,480 --> 00:14:23,140 Why do I think there's more to this than you're telling me? 207 00:14:24,768 --> 00:14:27,007 No, I just lied to advance my career. 208 00:14:27,008 --> 00:14:30,300 Really? Just to say you had a fellowship. Why would you do that? 209 00:14:35,583 --> 00:14:37,103 My family are all doctors. 210 00:14:37,128 --> 00:14:39,127 I was always going to be a surgeon. 211 00:14:39,128 --> 00:14:41,140 It was more or less decided for me. 212 00:14:42,728 --> 00:14:45,847 Final year of medical school, I was walking to uni 213 00:14:45,848 --> 00:14:49,087 and a cyclist is knocked off her bike, right in front of me. 214 00:14:49,088 --> 00:14:50,927 Now, I was a keen student. 215 00:14:50,928 --> 00:14:53,540 I used to carry a first aid kit around with me. 216 00:14:54,008 --> 00:14:57,300 If I'm honest, I was always waiting for something like this. 217 00:14:57,688 --> 00:15:00,620 When I think about that it's actually what I'm most ashamed of. 218 00:15:01,088 --> 00:15:03,020 She had facial injuries. 219 00:15:03,368 --> 00:15:06,215 Heavy, laboured breathing. She was losing consciousness fast. 220 00:15:06,240 --> 00:15:07,940 So, I thought, "She's suffocating. 221 00:15:08,160 --> 00:15:12,100 "She needs a surgical airway, a cricothyroidotomy." 222 00:15:12,520 --> 00:15:13,879 So, I made my incision. 223 00:15:13,880 --> 00:15:16,140 Something that I had practised on mannequins. 224 00:15:16,400 --> 00:15:20,060 What I didn't know is that she had an abnormal anatomy - 225 00:15:20,560 --> 00:15:24,220 an aberrant subclavian artery, looping high in the neck. 226 00:15:25,160 --> 00:15:28,479 It's present in 1% of people and 0% of mannequins. 227 00:15:28,480 --> 00:15:31,060 - How could you have known? - It was a bloodbath. 228 00:15:38,388 --> 00:15:41,228 The artery retracted back into her chest. 229 00:15:41,345 --> 00:15:43,600 There was nothing we could do to save her. 230 00:15:44,000 --> 00:15:46,420 She bled to death in minutes. 231 00:15:50,380 --> 00:15:53,340 My father was furious. 232 00:15:54,620 --> 00:15:57,239 Not because I stupidly tried a tracheostomy 233 00:15:57,240 --> 00:15:59,240 and killed an innocent young girl. 234 00:16:00,840 --> 00:16:04,740 But because I didn't study hard enough to do it competently. 235 00:16:06,620 --> 00:16:11,039 So, he used his influence and arranged for my fellowship 236 00:16:11,040 --> 00:16:13,300 - as cover. - For what? 237 00:16:17,040 --> 00:16:18,520 For my absence. 238 00:16:21,840 --> 00:16:25,120 It took months of therapy before I could even leave the house. 239 00:16:33,880 --> 00:16:37,479 The irony in all of this is that the one who helped me out 240 00:16:37,480 --> 00:16:39,160 the most was Emily Braithwaite. 241 00:16:40,318 --> 00:16:43,260 She visited me more often than my parents. 242 00:16:46,240 --> 00:16:47,480 She understood. 243 00:16:50,149 --> 00:16:52,469 But there was no way I was going to be a surgeon. 244 00:16:56,400 --> 00:16:58,540 So, I decided to choose pathology, 245 00:16:59,040 --> 00:17:02,920 and a false narrative was created as to why I made the switch. 246 00:17:04,600 --> 00:17:06,900 When you start lying, 247 00:17:07,520 --> 00:17:09,420 you have to keep lying. 248 00:17:29,373 --> 00:17:30,240 Jack. 249 00:17:30,264 --> 00:17:31,616 - Mm? - I need to talk to you. 250 00:17:31,640 --> 00:17:33,000 Sure, what's up...? 251 00:17:35,520 --> 00:17:36,420 Hi. 252 00:17:36,920 --> 00:17:38,040 Are you kidding me? 253 00:17:41,400 --> 00:17:43,759 He doesn't work here any more because he lied to us, do you 254 00:17:43,760 --> 00:17:46,227 - remember? Do you remember that? - Adam's got a theory about Wilfred. 255 00:17:46,228 --> 00:17:47,799 - Oh, right. - Just hear him out. 256 00:17:47,800 --> 00:17:52,039 So, um, I just have to trust him now? 257 00:17:52,040 --> 00:17:54,320 No, you've got to trust me. 258 00:17:57,773 --> 00:17:59,040 Think about it. 259 00:18:00,116 --> 00:18:02,880 Why would someone want Wilfred dead? 260 00:18:03,000 --> 00:18:05,279 What did he know that was such a threat that someone 261 00:18:05,280 --> 00:18:06,540 had to kill him? 262 00:18:07,740 --> 00:18:11,080 Wilfred was being treated for acute myeloid leukaemia. 263 00:18:11,400 --> 00:18:12,639 That's rare. 264 00:18:12,640 --> 00:18:15,159 Remember, he said there were lots of other cases in his small 265 00:18:15,160 --> 00:18:16,740 village in Africa. 266 00:18:17,360 --> 00:18:20,079 What if Wilfred wasn't killed because of what he knew? 267 00:18:20,080 --> 00:18:21,119 Don't follow. 268 00:18:21,120 --> 00:18:23,300 Wilfred wasn't the witness. 269 00:18:25,200 --> 00:18:26,660 He was the evidence. 270 00:18:29,780 --> 00:18:32,399 This is a trephine biopsy of the bone marrow. 271 00:18:32,400 --> 00:18:35,960 We take a thin core of bone with marrow cells in it. 272 00:18:36,120 --> 00:18:38,700 I've already taken an aspirate of the fluids. 273 00:18:49,540 --> 00:18:53,159 So, the question is, why would so many people from one place 274 00:18:53,160 --> 00:18:54,940 all get leukaemia? 275 00:18:55,800 --> 00:18:57,460 And that's going to tell you, is it? 276 00:18:57,640 --> 00:18:59,479 To be honest, I've never done this before. 277 00:18:59,480 --> 00:19:01,100 Not postmortem, anyway. 278 00:19:01,292 --> 00:19:03,657 But you know what? It's crazy enough for it to work. 279 00:19:03,960 --> 00:19:05,320 Mm-mm. 280 00:19:16,563 --> 00:19:17,603 Thanks. 281 00:19:19,352 --> 00:19:23,100 Oh, look. Here's a billion DNA results from the needles. 282 00:19:24,260 --> 00:19:26,460 Want to give me a hand going through these? 283 00:19:27,400 --> 00:19:28,560 Didn't think so. 284 00:19:46,364 --> 00:19:49,044 Nikki? The slide's ready when you want to have a look. 285 00:19:57,640 --> 00:20:00,279 Good yield of cells. More than I expected. 286 00:20:00,280 --> 00:20:02,719 Definitely acute myeloid leukaemia. 287 00:20:02,720 --> 00:20:05,880 It's not typical. Looks more like secondary AML. 288 00:20:06,200 --> 00:20:08,639 - Secondary to what? - A toxin of some sort. 289 00:20:08,640 --> 00:20:10,959 Some industrial chemical, for example, 290 00:20:10,960 --> 00:20:14,500 or chemotherapy for a different cancer. 291 00:20:14,960 --> 00:20:17,839 Right. And that can occur years after the original exposure. 292 00:20:17,840 --> 00:20:19,580 Decades, in some cases. 293 00:20:19,840 --> 00:20:23,540 So, there may be other victims, all exposed to the same thing? 294 00:20:25,440 --> 00:20:26,800 Makes sense. 295 00:20:45,453 --> 00:20:46,613 Can I help you? 296 00:20:46,638 --> 00:20:48,678 They told me Wilfred is here. 297 00:20:48,880 --> 00:20:50,380 Can I see him, yeah? 298 00:20:50,720 --> 00:20:53,180 - Er, you are? - Family. 299 00:20:55,200 --> 00:20:56,759 Do you want to take a seat? 300 00:20:56,760 --> 00:20:58,748 Will I be able to sit with him for a bit or...? 301 00:20:58,772 --> 00:21:00,040 I'll just check. 302 00:21:09,159 --> 00:21:11,479 I've found Rahul's murder weapon. 303 00:21:11,760 --> 00:21:15,519 One DNA profile matching Rahul, one matching Wilfred, 304 00:21:15,520 --> 00:21:17,279 just like we found at the scene. 305 00:21:17,280 --> 00:21:19,540 But there's a third profile. 306 00:21:21,040 --> 00:21:23,159 Yep. Simi Jacobs. 307 00:21:23,160 --> 00:21:25,199 Simi? He's here! 308 00:21:25,200 --> 00:21:28,120 What do you mean he's here? He wants to see Wilfred's body. 309 00:21:42,864 --> 00:21:45,664 This places Simi at the scene of Rahul's murder. 310 00:21:46,000 --> 00:21:47,820 We need to keep him here. 311 00:21:48,000 --> 00:21:49,600 Call DI Cracknell. 312 00:21:53,181 --> 00:21:54,319 So, hang on. 313 00:21:54,320 --> 00:21:55,677 Simi Jacobs just turned up at the lab. 314 00:21:55,701 --> 00:21:57,860 One needle injected into three people. 315 00:21:57,861 --> 00:21:59,300 Better get down here. 316 00:21:59,301 --> 00:22:01,655 Simi had a puncture wound to his neck. 317 00:22:01,680 --> 00:22:04,100 Rahul was stabbed in the chest, but Wilfred? 318 00:22:04,540 --> 00:22:06,439 And if Simi got in a fight with Rahul, 319 00:22:06,440 --> 00:22:08,159 why is Wilfred's blood spattered? 320 00:22:08,160 --> 00:22:11,079 Wilfred would have to have been in the room as well. 321 00:22:11,080 --> 00:22:13,080 Maybe he was. Genetically speaking. 322 00:22:14,400 --> 00:22:16,919 What if that needle only stabbed two people? 323 00:22:16,920 --> 00:22:18,803 Then one of them has two different types of DNA. 324 00:22:18,827 --> 00:22:19,776 Exactly. 325 00:22:19,800 --> 00:22:21,613 Huh? No, for that to work, it would 326 00:22:21,638 --> 00:22:23,599 mean Simi's walking around with Wilfred's blood inside him. 327 00:22:23,632 --> 00:22:25,576 - That's ridiculous. - Is it? 328 00:22:27,825 --> 00:22:31,119 - Bone marrow transplant. - And Wilfred was the donor. 329 00:22:31,120 --> 00:22:35,343 So, Simi's blood has Wilfred's DNA. 330 00:22:42,260 --> 00:22:43,980 Do you want to come this way? Yeah. 331 00:22:48,420 --> 00:22:49,500 Just there. 332 00:22:52,640 --> 00:22:55,399 Can I get you a tea? A glass of water or...? 333 00:22:55,400 --> 00:22:56,840 Oh, no, no! 334 00:22:57,280 --> 00:22:58,320 Thanks. 335 00:23:01,280 --> 00:23:03,600 You said that Wilfred was family? 336 00:23:03,680 --> 00:23:04,980 That's right. 337 00:23:05,931 --> 00:23:07,400 Was he a close relative? 338 00:23:08,720 --> 00:23:10,420 You ask a lot of questions. 339 00:23:11,040 --> 00:23:12,460 Remember me? 340 00:23:14,520 --> 00:23:16,300 I examined you at the station. 341 00:23:16,640 --> 00:23:17,959 I saw a scar on your chest. 342 00:23:17,960 --> 00:23:19,600 That's a Hickman line scar. 343 00:23:21,200 --> 00:23:23,220 Did you have a bone marrow transplant as a kid? 344 00:23:24,960 --> 00:23:26,759 Yeah, I'm going to go. 345 00:23:26,760 --> 00:23:29,840 Simi, we found your blood at the scene of Rahul's murder. 346 00:23:31,600 --> 00:23:32,840 Did you kill him? 347 00:23:35,680 --> 00:23:39,920 No, no, no. He... He came at me! He was insane! 348 00:23:40,360 --> 00:23:41,840 It was an accident! 349 00:23:45,760 --> 00:23:47,640 I just wanted to protect Wilfred. 350 00:23:49,640 --> 00:23:51,900 Wilfred saved my life when I was a kid. 351 00:23:52,440 --> 00:23:55,280 But you know what? He could only do that because he was a match. 352 00:23:55,480 --> 00:23:58,359 People have transplants from their brothers or mothers or whatever 353 00:23:58,360 --> 00:24:01,620 because they're a match. I had no-one. 354 00:24:02,680 --> 00:24:04,200 How did you find him? 355 00:24:04,224 --> 00:24:06,135 There's this charity attached to our church. 356 00:24:06,160 --> 00:24:08,160 They helped us get the transplant records. 357 00:24:09,698 --> 00:24:11,640 Only it turns out Wilfred was sick. 358 00:24:12,660 --> 00:24:14,600 - Were there others? - Yeah. 359 00:24:14,860 --> 00:24:18,040 I mean, loads of people in his village died from the same thing. 360 00:24:19,900 --> 00:24:21,540 We found Wilfred in time. 361 00:24:24,100 --> 00:24:25,540 So we thought. 362 00:24:27,460 --> 00:24:28,460 What? 363 00:24:29,620 --> 00:24:31,340 You're not going to let me see him? 364 00:24:35,420 --> 00:24:36,980 Simi. 365 00:24:38,140 --> 00:24:39,380 There he is. 366 00:24:59,900 --> 00:25:03,060 Ah, afternoon! Present from DI Cracknell - 367 00:25:03,340 --> 00:25:06,179 all the rubbish from Simi Jacobs' address. 368 00:25:06,180 --> 00:25:07,659 Thought you might want to take a look 369 00:25:07,660 --> 00:25:09,459 in case you find anything relevant. 370 00:25:09,460 --> 00:25:10,320 Joy. 371 00:25:10,344 --> 00:25:13,720 Can I introduce Reverend Kanu? You've already met Jack. 372 00:25:13,820 --> 00:25:15,720 This is Dr Nikki Alexander... 373 00:25:15,744 --> 00:25:17,441 - Hello. - And Dr Adam Yuen. 374 00:25:17,902 --> 00:25:21,259 Reverend Kanu runs the charitable organisation that was responsible 375 00:25:21,260 --> 00:25:23,139 for bringing Wilfred to the UK. 376 00:25:23,140 --> 00:25:24,939 I have some photos from our trip. 377 00:25:24,940 --> 00:25:27,640 Sergeant Galloway thinks they might help you. 378 00:25:27,664 --> 00:25:28,636 Thank you. 379 00:25:28,660 --> 00:25:31,440 I have to warn you, they're not pretty. 380 00:25:34,260 --> 00:25:36,500 Tell me how Mr Okoye came to be here. 381 00:25:38,075 --> 00:25:42,060 My church runs a charity that helps arrange treatment in the UK. 382 00:25:42,300 --> 00:25:45,340 They raise money, get doctors to volunteer, whatever. 383 00:25:46,580 --> 00:25:48,580 Wilfred's case was kind of special. 384 00:25:48,940 --> 00:25:52,420 I mean, he helped me years ago, and now he needed my help. 385 00:25:52,620 --> 00:25:54,800 The local newspaper picked up the story, 386 00:25:54,825 --> 00:25:56,320 it got a lot of publicity. 387 00:25:56,499 --> 00:25:58,316 So, the hospital agreed to treat him. 388 00:25:58,340 --> 00:26:01,040 - And he stayed at your flat? - Yeah. 389 00:26:03,060 --> 00:26:05,260 Nobody told me he don't speak English. 390 00:26:05,940 --> 00:26:07,740 I couldn't tell him anything. 391 00:26:08,780 --> 00:26:12,340 He didn't know who I was, what he did for me. 392 00:26:14,380 --> 00:26:17,180 Then I learnt that he's under the care of this Rahul guy. 393 00:26:19,020 --> 00:26:23,420 I have travelled widely in Africa as part of my ministry, 394 00:26:23,820 --> 00:26:29,220 and yet nothing could have prepared me for what we found in Bwendora. 395 00:26:31,580 --> 00:26:35,180 The town is remote, even by African standards. 396 00:26:36,340 --> 00:26:39,100 There is only very basic health care. 397 00:26:39,580 --> 00:26:42,380 It became clear there was a lot of sickness. 398 00:26:44,180 --> 00:26:47,340 This man died within hours of our arrival. 399 00:26:48,140 --> 00:26:52,579 The illness causes bleeding and rashes. Fever sometimes. 400 00:26:52,580 --> 00:26:54,739 What do the people think it's caused by? 401 00:26:54,740 --> 00:26:57,859 There's a large pesticide factory in the town. 402 00:26:57,860 --> 00:27:01,019 Many people think the water has been contaminated. 403 00:27:01,020 --> 00:27:03,979 They organised protests. 404 00:27:03,980 --> 00:27:06,939 People think there has been a cover-up. 405 00:27:06,940 --> 00:27:09,700 But the factory provides a lot of employment. 406 00:27:10,700 --> 00:27:14,140 It is a very divisive issue. 407 00:27:14,420 --> 00:27:18,820 The illness has ripped the heart out of the community. 408 00:27:19,140 --> 00:27:22,179 There are very few families it has left untouched. 409 00:27:22,180 --> 00:27:24,139 And they've had no outside help? 410 00:27:24,140 --> 00:27:27,380 There is one western charity which runs a clinic, 411 00:27:27,405 --> 00:27:29,285 but they only visit every few months. 412 00:27:32,088 --> 00:27:33,288 Some charity. 413 00:27:35,900 --> 00:27:37,220 Oh, Lord. 414 00:27:38,083 --> 00:27:40,307 Enlighten our minds with your truth. 415 00:27:42,300 --> 00:27:45,900 Give us the strength and the wisdom to seek justice. 416 00:27:47,140 --> 00:27:51,340 Shine your everlasting light into our darkness. 417 00:27:53,300 --> 00:27:56,460 There's a lot of talk about Rahul, all around the hospital. 418 00:27:56,700 --> 00:27:59,139 How the hospital is protecting him. 419 00:27:59,140 --> 00:28:02,180 How he messed up an operation and no-one wants to work with him. 420 00:28:02,580 --> 00:28:05,299 And you thought he shouldn't operate on Wilfred. 421 00:28:05,300 --> 00:28:09,299 The night before, I heard him arguing with this woman, 422 00:28:09,300 --> 00:28:11,419 Dr Braithwaite. 423 00:28:11,420 --> 00:28:13,499 She told Rahul not to do the operation 424 00:28:13,500 --> 00:28:15,820 and he just told her that she couldn't stop him. 425 00:28:16,300 --> 00:28:18,819 The bag of rubbish that we found at your home address. 426 00:28:18,820 --> 00:28:20,820 Was it from one of the offices? 427 00:28:20,983 --> 00:28:22,703 - Yeah. - Which one? 428 00:28:23,340 --> 00:28:24,739 All of them. 429 00:28:24,740 --> 00:28:27,179 I was looking for something, anything, 430 00:28:27,180 --> 00:28:29,019 I could use against Rahul. 431 00:28:29,020 --> 00:28:31,499 And on the morning of the operation? 432 00:28:31,500 --> 00:28:34,459 I saw Wilfred getting prepared for theatre and I panicked. 433 00:28:34,460 --> 00:28:36,219 I phoned Rahul. 434 00:28:36,220 --> 00:28:37,699 What did you say? 435 00:28:37,700 --> 00:28:40,059 I told him I had some information on him. 436 00:28:40,060 --> 00:28:44,179 I thought I could threaten to reveal what I knew if he did the operation. 437 00:28:44,180 --> 00:28:45,698 What information? 438 00:28:47,900 --> 00:28:51,409 I was bluffing. But I had to stop him. 439 00:28:54,180 --> 00:28:56,087 Well, you certainly managed that. 440 00:29:11,140 --> 00:29:12,619 How's it going? 441 00:29:12,620 --> 00:29:16,700 Oh, I'm in my element rummaging through the trash. You know me. 442 00:29:17,100 --> 00:29:19,459 Nothing much here, apart from a criminally lax attitude 443 00:29:19,460 --> 00:29:20,740 to recycling. 444 00:29:22,700 --> 00:29:24,699 Adam's still here, is he? 445 00:29:24,700 --> 00:29:26,699 We wouldn't have got this far without him. 446 00:29:26,700 --> 00:29:28,460 I want to trust him. 447 00:29:30,740 --> 00:29:31,860 What's that? 448 00:29:36,780 --> 00:29:38,068 Oh, my God. 449 00:29:39,300 --> 00:29:43,899 This was in that rubbish bag you found at Simi Jacobs' place. 450 00:29:43,900 --> 00:29:47,295 It's Harry Fletcher's ECG, taken the day of his operation. 451 00:29:47,320 --> 00:29:48,599 It's normal. 452 00:29:48,600 --> 00:29:52,199 And this is the ECG that appeared in Fletcher's notes. 453 00:29:52,200 --> 00:29:55,279 Same date and time, but grossly abnormal. 454 00:29:55,280 --> 00:29:59,079 We believe they were switched to deflect blame from Rahul 455 00:29:59,080 --> 00:30:01,140 after the operation went wrong. 456 00:30:01,440 --> 00:30:03,180 So, there was a cover-up? 457 00:30:03,400 --> 00:30:06,119 Well, what's this got to do with the murder investigation? 458 00:30:06,120 --> 00:30:09,079 Yeah, Simi Jacobs admitted to the attack on Arnie Rahul. 459 00:30:09,080 --> 00:30:11,959 I mean, he claims it was an accident as a result of self-defence. 460 00:30:11,960 --> 00:30:13,679 That fits with the crime scene findings. 461 00:30:13,680 --> 00:30:16,039 So, how does this transplant fit in? 462 00:30:16,040 --> 00:30:18,799 Well, Simi was born with sickle cell disease, 463 00:30:18,800 --> 00:30:22,959 and was treated with a bone marrow transplant at St Jude's as a child. 464 00:30:22,960 --> 00:30:25,759 Wilfred donated his stem cells for Simi's transplant. 465 00:30:25,760 --> 00:30:28,375 20 years later, Wilfred gets leukaemia. 466 00:30:28,400 --> 00:30:30,279 We don't think this is a coincidence. 467 00:30:30,280 --> 00:30:33,519 He had a type of leukaemia that can be caused by over-exposure 468 00:30:33,520 --> 00:30:34,559 to certain drugs. 469 00:30:34,560 --> 00:30:37,239 There's a technique known as mobilisation, 470 00:30:37,240 --> 00:30:40,600 which is designed to increase production of stem cells. 471 00:30:40,677 --> 00:30:45,279 Normally, stem cell donation involves giving a perfectly safe 472 00:30:45,280 --> 00:30:46,799 bone marrow stimulant. 473 00:30:46,800 --> 00:30:51,719 But whoever did this also gave Wilfred high levels of chemotherapy, 474 00:30:51,720 --> 00:30:53,359 and did so repeatedly. 475 00:30:53,360 --> 00:30:55,919 They gave chemo? To a volunteer? 476 00:30:55,920 --> 00:30:57,839 To yield even more stem cells. 477 00:30:57,840 --> 00:31:00,079 What for? More transplants? 478 00:31:00,080 --> 00:31:04,679 Stem cells have the ability to develop into any type of body cell. 479 00:31:04,680 --> 00:31:06,895 Brain, heart, blood - you name it. 480 00:31:06,920 --> 00:31:09,239 So there's a huge range of potential therapies 481 00:31:09,240 --> 00:31:12,799 in which they can be used, one of which is transplantation. 482 00:31:12,800 --> 00:31:17,852 About ten years ago, Braithwaite and her team identified stem cells 483 00:31:17,877 --> 00:31:19,679 that were very special indeed, 484 00:31:19,680 --> 00:31:23,239 capable of being turned into what are called killer T-cells, 485 00:31:23,240 --> 00:31:27,319 part of the immune system, which can be made to attack malignant tumours. 486 00:31:27,320 --> 00:31:29,679 The potential for this discovery was enormous. 487 00:31:29,680 --> 00:31:31,999 These magic cells all had the same gene, 488 00:31:32,000 --> 00:31:35,920 a gene we think might be common in Wilfred's town. 489 00:31:36,320 --> 00:31:40,119 They went looking for transplant donors to treat people like Simi, 490 00:31:40,120 --> 00:31:42,919 but what they discovered was something much bigger, 491 00:31:42,920 --> 00:31:45,039 so they went back for more, and more. 492 00:31:45,040 --> 00:31:47,679 Basically they were flogging him for every last stem cell 493 00:31:47,680 --> 00:31:50,079 - he could produce. - Him and all the others. 494 00:31:50,080 --> 00:31:52,399 Wilfred's town was basically a stem cell farm. 495 00:31:52,400 --> 00:31:55,839 Can you prove Wilfred was given the stimulating drugs? 496 00:31:55,840 --> 00:31:59,300 It may be possible, but that's way out of my league. 497 00:32:00,760 --> 00:32:02,640 Sounds like we need a second opinion. 498 00:32:22,640 --> 00:32:23,759 Thank you, Professor. 499 00:32:23,760 --> 00:32:25,599 Not at all. It's very good to see you. 500 00:32:25,600 --> 00:32:27,120 - Thank you. - Oh, he's away! 501 00:32:28,967 --> 00:32:32,519 - Adam, hello again. - Hello. This is Dr Nikki Alexander. 502 00:32:32,520 --> 00:32:33,800 - Hello. - How do you do? 503 00:32:33,824 --> 00:32:35,136 And you've already met DI Cracknell. 504 00:32:35,160 --> 00:32:36,760 Yes, of course. This way. 505 00:32:37,524 --> 00:32:39,204 That was Alfie. 506 00:32:39,400 --> 00:32:42,919 He's one of our early trial patients osteosarcoma. 507 00:32:42,920 --> 00:32:45,639 When he was referred to us, he was in a hospice 508 00:32:45,640 --> 00:32:48,940 on palliative treatment, expected to die within weeks. 509 00:32:48,989 --> 00:32:51,389 Please. That was two years ago. 510 00:32:52,508 --> 00:32:54,100 He's now disease-free. 511 00:32:56,620 --> 00:33:00,279 We wanted to show you some bone marrow samples from Mr Okoye. 512 00:33:00,280 --> 00:33:02,840 He was moved from St Jude's to be treated here. 513 00:33:10,887 --> 00:33:12,380 Hmm. 514 00:33:12,847 --> 00:33:14,487 Secondary leukaemia. 515 00:33:17,367 --> 00:33:18,846 They look very unusual. 516 00:33:18,847 --> 00:33:21,260 Mr Okoye was a stem cell donor. 517 00:33:21,687 --> 00:33:23,100 Was he? 518 00:33:23,407 --> 00:33:26,220 We were wondering if it might be stimulated. 519 00:33:26,647 --> 00:33:28,420 You mean Cyclo-G? 520 00:33:29,327 --> 00:33:30,540 Oh, dear. 521 00:33:30,807 --> 00:33:34,020 Yes, it's possible. 522 00:33:34,367 --> 00:33:36,660 Is there any way we can confirm it? 523 00:33:37,287 --> 00:33:40,166 You would need to look into the genetics of his blood cells. 524 00:33:40,167 --> 00:33:42,286 There are some telltale signs. 525 00:33:42,287 --> 00:33:45,646 We have several world experts in cytogenetics here. 526 00:33:45,647 --> 00:33:47,480 They'd be happy to help. 527 00:33:47,887 --> 00:33:51,055 Your cancer therapies are based on Braithwaite's stem cell research, 528 00:33:51,080 --> 00:33:55,199 - are they not? - Yes. Yes. I've never denied it. 529 00:33:55,200 --> 00:33:57,880 Hers was an extraordinary piece of work. 530 00:33:59,040 --> 00:34:02,119 She tried for years to turn it into a practical treatment, 531 00:34:02,120 --> 00:34:06,719 but, in the end, she was stumped by the obvious problem. 532 00:34:06,720 --> 00:34:08,599 The limited supply of donors. 533 00:34:08,600 --> 00:34:09,800 Precisely. 534 00:34:09,880 --> 00:34:14,460 So, what we brought to the party is called gene editing. 535 00:34:15,520 --> 00:34:18,439 We found a way of inserting the special gene 536 00:34:18,440 --> 00:34:21,840 into any old stem cell, and the result is... 537 00:34:22,340 --> 00:34:24,120 Well, you met Alfie. 538 00:34:25,200 --> 00:34:27,820 What is your relationship to Emily Braithwaite? 539 00:34:29,140 --> 00:34:30,420 Yes. 540 00:34:30,800 --> 00:34:33,660 Well, I suppose you'd say we're rivals. 541 00:34:33,960 --> 00:34:37,300 She's never forgiven me for succeeding where she failed. 542 00:34:37,840 --> 00:34:41,839 But I'm afraid her star has been waning for some time. 543 00:34:41,840 --> 00:34:43,280 What makes you say that? 544 00:34:45,403 --> 00:34:47,403 She came to ask for my help. 545 00:34:47,428 --> 00:34:50,839 Believe me, that alone suggests desperation. 546 00:34:50,840 --> 00:34:54,720 She had just lost a very large research grant. 547 00:34:55,000 --> 00:34:57,559 Is it possible that Braithwaite poisoned Mr Okoye 548 00:34:57,560 --> 00:35:00,520 and everyone else in his town to get more stem cells? 549 00:35:00,920 --> 00:35:03,140 That's a serious accusation. 550 00:35:03,500 --> 00:35:05,220 Everything's falling apart. 551 00:35:05,480 --> 00:35:07,879 So, like a gambler, she risks more and more, 552 00:35:07,880 --> 00:35:10,560 desperate for that big win to get herself back on top. 553 00:36:05,876 --> 00:36:07,680 - Now what? - Excuse me? 554 00:36:08,346 --> 00:36:11,586 - You do realise my career is over? - And that's my fault? 555 00:36:11,913 --> 00:36:13,719 There's got to be a way out of this. 556 00:36:13,720 --> 00:36:15,240 You owe me that at least. 557 00:36:16,332 --> 00:36:18,972 You want Auntie Emily to make it better? 558 00:36:20,469 --> 00:36:23,860 All those years I stuck up for you with your father. 559 00:36:24,540 --> 00:36:27,020 You messed up. Again. 560 00:36:27,500 --> 00:36:29,560 For once in your life, own it. 561 00:36:31,680 --> 00:36:32,980 I don't get it. 562 00:36:33,280 --> 00:36:34,799 You and Rahul. 563 00:36:34,800 --> 00:36:36,999 You go to all these lengths to protect his reputation, 564 00:36:37,000 --> 00:36:39,759 yet you show no interest in who might have killed him. 565 00:36:39,760 --> 00:36:42,120 You don't even seem to even care that he's dead! 566 00:36:43,520 --> 00:36:46,080 Maybe I've learnt to bury my emotions. 567 00:36:48,068 --> 00:36:49,268 You should try it. 568 00:36:51,040 --> 00:36:52,760 You know they're onto you, 569 00:36:53,120 --> 00:36:55,020 and I'm not going to help you this time. 570 00:36:55,238 --> 00:36:56,780 Oh, please. 571 00:36:58,720 --> 00:37:00,160 This is so painful. 572 00:37:06,920 --> 00:37:09,359 So, all roads lead to Braithwaite. 573 00:37:09,360 --> 00:37:11,460 Yes, but it's all circumstantial. 574 00:37:11,680 --> 00:37:14,359 There's nothing directly connecting her to Wilfred. 575 00:37:14,360 --> 00:37:16,842 If you can find me something concrete, I'll bring her in, 576 00:37:16,867 --> 00:37:18,639 but until then, it's just speculation. 577 00:37:18,640 --> 00:37:20,500 Adam, where did you get to? 578 00:37:21,040 --> 00:37:23,975 Rahul's conduct during Fletcher's operation amounted to 579 00:37:24,000 --> 00:37:25,559 criminal negligence. 580 00:37:25,560 --> 00:37:27,639 He could have been charged for manslaughter. 581 00:37:27,640 --> 00:37:29,039 Well, he's dead. 582 00:37:29,040 --> 00:37:30,919 What if Braithwaite covered it up? 583 00:37:30,920 --> 00:37:33,559 That's attempting to pervert the course of justice. 584 00:37:33,560 --> 00:37:34,959 Which means you can arrest her. 585 00:37:34,960 --> 00:37:38,359 Oh, and how do we know that Braithwaite swaps the ECG? 586 00:37:38,360 --> 00:37:40,759 We can't. There are several sets of prints on the trace, 587 00:37:40,760 --> 00:37:42,159 one of which could be Braithwaite's. 588 00:37:42,160 --> 00:37:44,519 Exactly, so we can't just arrest her on the off-chance that 589 00:37:44,520 --> 00:37:45,919 - her prints are on there. - I know. 590 00:37:45,920 --> 00:37:47,720 I met her for a drink. 591 00:37:50,980 --> 00:37:52,740 Her prints are on this glass. 592 00:37:52,765 --> 00:37:56,481 When you find that they are the same as the sets on the ECG, 593 00:37:56,582 --> 00:37:59,055 - then you can arrest her. - That's not admissible as evidence! 594 00:37:59,080 --> 00:38:00,720 It doesn't have to be. 595 00:38:01,903 --> 00:38:05,200 How do we know for sure she touched this glass? 596 00:38:05,640 --> 00:38:07,840 Well, you're just going to have to trust me. 597 00:38:54,480 --> 00:38:55,960 You two go round the back. 598 00:39:07,600 --> 00:39:09,820 Her car's here. Looks like she's home. 599 00:39:12,760 --> 00:39:13,800 No letterbox. 600 00:39:18,280 --> 00:39:19,640 Dr Braithwaite? 601 00:39:20,640 --> 00:39:23,140 DS Galloway. Could you open the door, please? 602 00:39:27,360 --> 00:39:29,820 - Police! - Dr Braithwaite? 603 00:39:41,600 --> 00:39:42,680 Shit. 604 00:39:48,960 --> 00:39:51,060 No sign of external injury. 605 00:39:52,440 --> 00:39:55,839 Both front and back doors were locked from the inside. 606 00:39:55,840 --> 00:39:58,100 There's no signs of forced entry. 607 00:39:58,440 --> 00:40:00,300 Everything's neat and tidy. 608 00:40:02,120 --> 00:40:03,780 Sudden chest pain, maybe? 609 00:40:05,000 --> 00:40:06,340 Or suicide. 610 00:40:38,480 --> 00:40:41,580 Nikki. Adam. Look at these. 611 00:40:46,880 --> 00:40:50,340 Two samples with Wilfred Okoye's name on. 612 00:41:13,080 --> 00:41:14,500 Look at this. 613 00:41:15,040 --> 00:41:16,740 The boiler's locked out. 614 00:41:17,320 --> 00:41:18,980 Yeah. Mine does that all the time. 615 00:41:19,240 --> 00:41:20,620 Bloody things. 616 00:41:58,880 --> 00:42:01,440 Heart weighs 380g. 617 00:42:27,600 --> 00:42:30,500 Evidence of left ventricular hypertrophy. 618 00:42:31,800 --> 00:42:33,460 Valves unremarkable. 619 00:42:36,600 --> 00:42:40,200 Left anterior descending coronary artery. 620 00:42:40,440 --> 00:42:43,860 Moderate stenosis, no evidence of thrombus. 621 00:42:51,515 --> 00:42:54,359 The toxicology was entirely negative, 622 00:42:54,360 --> 00:42:56,820 apart from a modest level of alcohol. 623 00:42:57,080 --> 00:43:00,700 No paracetamol, no benzodiazepines, nothing. 624 00:43:01,040 --> 00:43:04,639 So this, together with the absence of pills and containers 625 00:43:04,640 --> 00:43:07,599 at the address, and the absence of any needle marks on the body, 626 00:43:07,600 --> 00:43:10,759 leads me to conclude that death was not as a result 627 00:43:10,760 --> 00:43:13,060 of suicide or poisoning. 628 00:43:13,320 --> 00:43:16,799 In fact, the only significant finding from the postmortem 629 00:43:16,800 --> 00:43:19,759 examination is moderate ischaemic heart disease, 630 00:43:19,760 --> 00:43:23,199 together with hypertrophy of the septum and left ventricular wall. 631 00:43:23,200 --> 00:43:26,159 But no evidence of coronary thrombosis? 632 00:43:26,160 --> 00:43:27,800 The ventricular wall thickness... 633 00:43:27,824 --> 00:43:29,415 - Heart attack. - ..and the degree 634 00:43:29,440 --> 00:43:32,999 of myocardial disarray on microscopy are borderline 635 00:43:33,000 --> 00:43:34,919 for a diagnosis of HCM. 636 00:43:34,920 --> 00:43:37,879 - What's that? - Hypertrophic cardiomyopathy. 637 00:43:37,880 --> 00:43:41,159 It's an inherited heart condition that can lead to sudden death. 638 00:43:41,160 --> 00:43:43,440 - Fabrice Muamba. - Yes. 639 00:43:44,968 --> 00:43:48,919 Bolton Wanderers versus Tottenham. FA Cup quarterfinal, 2012. 640 00:43:48,920 --> 00:43:50,839 He collapsed on the pitch. Nearly died. 641 00:43:50,840 --> 00:43:52,679 Well, technically he did. 642 00:43:52,680 --> 00:43:54,959 In cases of high stress or exercise, 643 00:43:54,960 --> 00:43:58,879 the heart can lead into an abnormal rhythm, which can be fatal. 644 00:43:58,880 --> 00:44:01,799 And Emily Braithwaite was under a lot of stress. 645 00:44:01,800 --> 00:44:05,719 So it is possible that this caused a dysrhythmic event... 646 00:44:05,720 --> 00:44:07,167 - Heart attack. - Heart attack. 647 00:44:07,192 --> 00:44:08,880 ..that led to her death, don't you think? 648 00:44:12,961 --> 00:44:14,960 How come she didn't have a letterbox? 649 00:44:14,961 --> 00:44:17,320 It's a passive house. It's so well-insulated, 650 00:44:17,321 --> 00:44:20,000 it doesn't need heating. You heat it up just by living in it. 651 00:44:20,001 --> 00:44:21,760 But it has to be really airtight. 652 00:44:21,761 --> 00:44:23,880 It's like living in a bubble. 653 00:44:23,881 --> 00:44:27,081 All the air goes in and out through a single ventilation system. 654 00:44:28,721 --> 00:44:30,620 But why would the boiler lock out? 655 00:44:31,460 --> 00:44:36,080 What if it was faulty and produced a lot of carbon monoxide? 656 00:44:36,081 --> 00:44:38,740 No carbon monoxide in the toxicology. 657 00:44:42,721 --> 00:44:45,320 She's a suspect in a murder case. She conveniently dies. 658 00:44:45,321 --> 00:44:47,160 What if others were involved? 659 00:44:47,161 --> 00:44:49,280 If you can tell me how they did it, I'll believe you, 660 00:44:49,281 --> 00:44:52,400 but until then, it's looking like natural causes. 661 00:44:52,801 --> 00:44:56,360 Right, then, provisional assumption is that Braithwaite 662 00:44:56,361 --> 00:44:59,080 was guilty of conspiracy to murder Wilfred Okoye, 663 00:44:59,081 --> 00:45:02,040 as well as perverting the course of justice in the Fletcher case. 664 00:45:02,041 --> 00:45:03,240 What about Simi? 665 00:45:03,241 --> 00:45:06,860 That's up to the CPS, whether they buy a self-defence plea. 666 00:45:07,281 --> 00:45:08,801 I'll keep you posted. 667 00:45:26,503 --> 00:45:28,783 So this is where you've been hiding. 668 00:45:31,281 --> 00:45:32,860 Adam told you, then? 669 00:45:33,081 --> 00:45:35,601 Oh, yeah. He told me everything. 670 00:46:32,001 --> 00:46:33,400 I don't get it. 671 00:46:33,401 --> 00:46:36,400 How could someone like Braithwaite justify it to herself, 672 00:46:36,401 --> 00:46:37,720 let alone anyone else? 673 00:46:37,721 --> 00:46:40,240 They get fixated on the prize, don't they? 674 00:46:40,241 --> 00:46:43,280 The breakthrough, and all the acclaim that goes with it. 675 00:46:43,304 --> 00:46:44,600 Mm. 676 00:46:44,921 --> 00:46:48,340 Did you ever want to do something like that? Fancy research job? 677 00:46:49,121 --> 00:46:50,961 I think you'd be really good at that. 678 00:46:53,881 --> 00:46:55,060 I don't know. 679 00:46:56,041 --> 00:46:58,340 - It's more Adam's world. - Mm. 680 00:46:59,081 --> 00:47:00,281 Not any more. 681 00:47:01,961 --> 00:47:04,500 You can see how liberated he's been. 682 00:47:04,721 --> 00:47:07,540 He's carried that secret around for so long. 683 00:47:07,801 --> 00:47:10,580 Well, he's stopped trying to be all things to all men. 684 00:47:11,361 --> 00:47:14,540 And I'll tell you, he loves beating himself up. 685 00:48:13,721 --> 00:48:17,240 Hi. I'm working on the case of Wilfred Okoye. 686 00:48:17,241 --> 00:48:19,655 I was wondering if I could get his microbiology results 687 00:48:19,680 --> 00:48:20,960 from his stay here. 688 00:48:21,120 --> 00:48:23,880 Date of birth is 9/7/66. 689 00:48:28,724 --> 00:48:31,324 I just need to, er, speak to my supervisor. 690 00:48:31,520 --> 00:48:32,760 OK. Thank you. 691 00:49:12,240 --> 00:49:13,620 It's Adam. 692 00:49:16,200 --> 00:49:17,860 "We were wrong about everything. 693 00:49:19,580 --> 00:49:22,660 - "At Cowley Institute. Come quickly." - What? 694 00:49:25,763 --> 00:49:27,480 What are we looking at? 695 00:49:27,800 --> 00:49:30,740 Wilfred's blood cultures. Microbiology report. 696 00:49:33,307 --> 00:49:34,547 Hang on. 697 00:49:35,722 --> 00:49:38,700 The antibiotic sensitivities have been reversed. 698 00:49:39,369 --> 00:49:40,849 Who's done that? Braithwaite? 699 00:49:41,044 --> 00:49:43,604 Couldn't be. These are from the Cowley institute. 700 00:49:46,221 --> 00:49:48,180 Adam needs us. Come on. 701 00:50:18,783 --> 00:50:21,623 Oh, great. We were supposed to go left back at the lights. 702 00:50:39,108 --> 00:50:40,228 Dr Yuen? 703 00:50:40,253 --> 00:50:42,540 You know Emily Braithwaite died yesterday? 704 00:50:43,600 --> 00:50:47,839 What? Uh, no. How did it happen? 705 00:50:47,840 --> 00:50:51,000 Unknown. Found dead in a house that was bolted from the inside. 706 00:50:52,520 --> 00:50:55,380 Oh, look, an oxygen analyser. 707 00:50:56,480 --> 00:50:58,159 Do you always keep one of those in your car? 708 00:50:58,160 --> 00:50:59,959 I use it for various things. 709 00:50:59,960 --> 00:51:03,239 So Emily died just as you convinced us she was guilty. 710 00:51:03,240 --> 00:51:05,960 Her work was based on exploitation. 711 00:51:06,200 --> 00:51:08,060 Well, she can't deny that now, can she? 712 00:51:08,215 --> 00:51:09,559 Well, whatever happened, 713 00:51:09,560 --> 00:51:12,559 I'm sure forensic science will find the answer. 714 00:51:12,621 --> 00:51:16,400 Mm. Then I realised just how much liquid nitrogen you go through here. 715 00:51:16,520 --> 00:51:18,520 Two deliveries in three days? 716 00:51:20,680 --> 00:51:23,420 I mean, that is some evil genius stuff. 717 00:51:23,780 --> 00:51:25,740 Pretty quick and very clean. 718 00:51:26,020 --> 00:51:29,420 Except the pilot light in the boiler went out at Braithwaite's house. 719 00:51:29,660 --> 00:51:31,380 Otherwise, the perfect crime. 720 00:51:32,260 --> 00:51:33,879 Are you insane? 721 00:51:33,880 --> 00:51:37,160 - Oh, sorry. That's forensic science. - Get out. 722 00:51:40,981 --> 00:51:43,700 Braithwaite had Wilfred's blood samples. She was onto you. 723 00:51:44,820 --> 00:51:46,959 My research is changing lives. 724 00:51:46,960 --> 00:51:48,679 She never made the crucial breakthrough, 725 00:51:48,680 --> 00:51:50,080 but then again, neither did you. 726 00:51:50,240 --> 00:51:52,399 You reckon you'll crack it any minute now, don't you? 727 00:51:52,400 --> 00:51:54,879 You just have to keep going, keep blasting innocent men 728 00:51:54,880 --> 00:51:57,039 and women with poisonous drugs, and then you'll get there. 729 00:51:57,040 --> 00:51:59,839 - You know nothing. - There's no gene editing going on here. 730 00:51:59,840 --> 00:52:02,559 Your magic treatments are all from stem cells that you get 731 00:52:02,560 --> 00:52:03,919 from killing people like Wilfred. 732 00:52:03,920 --> 00:52:07,519 When childhood cancer is a thing of the past thanks to me, 733 00:52:07,520 --> 00:52:09,060 no-one will care. 734 00:52:09,580 --> 00:52:11,660 That's what it's all about, isn't it? 735 00:52:12,560 --> 00:52:14,845 It's not about the money or the power. 736 00:52:15,766 --> 00:52:17,600 It's about the prestige. 737 00:52:18,492 --> 00:52:20,740 So what are you going to do about it, Adam? 738 00:52:21,060 --> 00:52:23,279 Mm? You're discredited. 739 00:52:23,280 --> 00:52:24,720 You're getting struck off. 740 00:52:25,935 --> 00:52:28,020 Of course I know! 741 00:52:28,420 --> 00:52:29,860 I know everything. 742 00:52:31,940 --> 00:52:34,380 You've no idea who you're dealing with. 743 00:52:36,780 --> 00:52:37,900 Adam? 744 00:52:40,380 --> 00:52:41,680 Adam! 745 00:52:47,400 --> 00:52:49,919 Adam? What's happening? 746 00:52:49,920 --> 00:52:52,780 Cowley's the one exploiting Wilfred and the rest of the donors. 747 00:52:53,260 --> 00:52:55,719 And he killed Braithwaite with liquid nitrogen. 748 00:52:55,720 --> 00:52:57,839 He poured it in the vent of her airtight house, 749 00:52:57,840 --> 00:53:00,879 turning it into a gas chamber. She suffocated. 750 00:53:00,880 --> 00:53:04,319 Cowley did a deal with Rahul to kill Wilfred during surgery. 751 00:53:04,320 --> 00:53:07,240 And when that failed, he attacked Wilfred with the bacteria... 752 00:53:09,087 --> 00:53:11,799 ..to make sure he switched the micro reports 753 00:53:11,800 --> 00:53:13,460 so that the antibiotics wouldn't work. 754 00:53:26,947 --> 00:53:28,147 Adam? 755 00:53:29,154 --> 00:53:30,474 Adam! 756 00:53:50,360 --> 00:53:53,960 - I'm sure that's Cowley. - Really? Call Cracknell. 757 00:53:54,000 --> 00:53:56,400 - But... - Get after him. I'll find Adam. 758 00:54:04,578 --> 00:54:08,578 Yeah, I'm heading north on Colbridge Road. 759 00:54:09,000 --> 00:54:11,240 It's a black Mercedes. 760 00:54:11,420 --> 00:54:12,600 Adam? 761 00:54:12,802 --> 00:54:13,922 Adam! 762 00:54:14,180 --> 00:54:15,540 Oh, Jesus. 763 00:54:18,900 --> 00:54:20,140 Ambulance. 764 00:54:26,540 --> 00:54:28,400 Can you hear me? Adam? 765 00:54:28,780 --> 00:54:30,660 You took your time, mate. 766 00:54:31,300 --> 00:54:32,940 Come to take all the credit? 767 00:54:34,540 --> 00:54:35,900 Oh, man. 768 00:54:36,900 --> 00:54:39,580 The ambulance is on its way. What happened? 769 00:54:40,020 --> 00:54:41,380 I messed up. 770 00:54:57,380 --> 00:54:58,700 You trusted me. 771 00:55:02,020 --> 00:55:03,460 That means a lot. 772 00:55:05,420 --> 00:55:07,899 Adam. Adam, stay with me. 773 00:55:07,900 --> 00:55:10,219 Adam. Come on, man. Stay with me. Stay with me. 774 00:55:10,220 --> 00:55:11,500 Come on! Adam! 775 00:55:12,780 --> 00:55:13,820 Adam! 776 00:56:00,720 --> 00:56:01,760 Oh, God. 777 00:56:08,754 --> 00:56:10,154 Oh, no. 60434

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