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These are the user uploaded subtitles that are being translated: 1 00:00:00,973 --> 00:00:03,723 (peaceful music) 2 00:00:10,695 --> 00:00:14,455 (children shouting) 3 00:00:14,455 --> 00:00:18,386 At 12, Cian Moore loved playing football 4 00:00:18,386 --> 00:00:20,947 until his eyes started to hurt 5 00:00:20,947 --> 00:00:25,447 He had trouble focusing, reading, even kicking a ball. 6 00:00:26,666 --> 00:00:29,456 He withdrew from people 7 00:00:29,456 --> 00:00:31,803 Cian was going blind. 8 00:00:31,803 --> 00:00:36,308 I was terrified because I don't want to go blind. 9 00:00:36,308 --> 00:00:38,720 For three years, his mother took him 10 00:00:38,720 --> 00:00:42,446 to many doctors, trying to find out why. 11 00:00:42,446 --> 00:00:46,084 Those three years were the worst of being told 12 00:00:46,084 --> 00:00:50,793 "There's nothing we can do," so it's like okay, he's blind, 13 00:00:50,793 --> 00:00:52,043 he'll be blind. 14 00:00:55,690 --> 00:00:58,322 What no doctor thought to prescribe through all of those 15 00:00:58,322 --> 00:01:02,725 consultations was these, just two capsules a year 16 00:01:02,725 --> 00:01:04,887 can save a child's sight. 17 00:01:04,887 --> 00:01:06,983 It can even save their life. 18 00:01:06,983 --> 00:01:10,025 In fact, this remedy has already saved over five million 19 00:01:10,025 --> 00:01:14,192 lives, but this isn't a medicine, it isn't a drug. 20 00:01:15,249 --> 00:01:16,749 This is vitamin A. 21 00:01:19,862 --> 00:01:23,589 But why was Cian so low in this vitamin? 22 00:01:23,589 --> 00:01:26,028 Well, since he was six year olds, he lived on bland 23 00:01:26,028 --> 00:01:29,973 foods such as chicken and chips, he wouldn't touch any 24 00:01:29,973 --> 00:01:32,706 fresh fruit or vegetables. 25 00:01:32,706 --> 00:01:36,808 He'd starve, he wouldn't care or if you would make him 26 00:01:36,808 --> 00:01:38,308 he would vomit it. 27 00:01:39,811 --> 00:01:42,557 Hundreds of thousands of malnourished children 28 00:01:42,557 --> 00:01:46,635 are on the brink of going blind because they lack vitamin A. 29 00:01:46,635 --> 00:01:50,106 Most are in developing countries, and caught early, 30 00:01:50,106 --> 00:01:52,439 their sight can be restored. 31 00:01:53,921 --> 00:01:57,381 For Cian, high dose vitamin A supplements saved the sight 32 00:01:57,381 --> 00:02:02,214 in his right eye, but he's permanently blind in the other. 33 00:02:03,246 --> 00:02:07,032 Vitamin A literally has the power to make the blind see, 34 00:02:07,032 --> 00:02:08,503 yet here's the rub. 35 00:02:08,503 --> 00:02:11,565 Taking extra vitamin A will not offer any benefit if you 36 00:02:11,565 --> 00:02:15,871 already have enough, and too much is toxic. 37 00:02:15,871 --> 00:02:17,204 It can kill you. 38 00:02:21,952 --> 00:02:25,941 In 1913, Antarctic explorers Douglas Mawson and Xavier 39 00:02:25,941 --> 00:02:29,695 Mertz were fighting for their lives. 40 00:02:29,695 --> 00:02:33,814 With most of their food gone, they faced a stark choice. 41 00:02:33,814 --> 00:02:35,647 Eat their dogs or die. 42 00:02:43,303 --> 00:02:48,013 After reluctantly eating their dogs, the men fell ill, 43 00:02:48,013 --> 00:02:49,596 burning with fever. 44 00:02:50,935 --> 00:02:53,856 Within days, Mertz was dead. 45 00:02:53,856 --> 00:02:57,773 Mawson, against the odds, made it back to camp. 46 00:02:59,737 --> 00:03:00,570 Ho! 47 00:03:02,380 --> 00:03:05,313 (dogs whining) 48 00:03:05,313 --> 00:03:07,704 So what was the mystery illness that 49 00:03:07,704 --> 00:03:11,605 killed Mertz and nearly cost Mawson his life? 50 00:03:11,605 --> 00:03:13,907 Well, when they ate their dogs, they weren't just eating 51 00:03:13,907 --> 00:03:18,907 canine flesh and fat, they also ate the dog's livers which 52 00:03:19,115 --> 00:03:21,865 contain high levels of vitamin A. 53 00:03:25,366 --> 00:03:28,040 So basically, they overdosed. 54 00:03:28,040 --> 00:03:32,873 Mertz went mad, his condition known as hypervitaminosis A. 55 00:03:34,765 --> 00:03:39,765 Hypervitaminosis A is rare, but deadly, and today, we know 56 00:03:40,097 --> 00:03:43,227 it can be caused by overuse of high dose vitamin A 57 00:03:43,227 --> 00:03:46,786 supplements, the same kind of supplements that can save 58 00:03:46,786 --> 00:03:48,119 a child's sight. 59 00:03:53,975 --> 00:03:58,975 This power and complexity lies at the heart of the great 60 00:03:59,215 --> 00:04:01,101 vitamin story. 61 00:04:01,101 --> 00:04:03,851 (dramatic music) 62 00:04:08,015 --> 00:04:11,684 I'm embarking on an epic, world spanning investigation 63 00:04:11,684 --> 00:04:14,184 of vitamin science in history. 64 00:04:15,976 --> 00:04:17,726 That is one big fish. 65 00:04:18,734 --> 00:04:21,680 I want to know how we discovered them. 66 00:04:21,680 --> 00:04:23,513 You sure this is safe? 67 00:04:25,968 --> 00:04:27,620 What they actually are. 68 00:04:27,620 --> 00:04:30,484 The 13 vitamins can be divided into two teams. 69 00:04:30,484 --> 00:04:32,817 How we learnt to build them. 70 00:04:33,720 --> 00:04:35,844 Tonight, Walgreens and Target have pulled 71 00:04:35,844 --> 00:04:37,074 the products nationwide. 72 00:04:37,074 --> 00:04:39,128 And how safe they are. 73 00:04:39,128 --> 00:04:40,947 All vitamins, all nutrients, 74 00:04:40,947 --> 00:04:43,059 they are toxic in high amounts. 75 00:04:43,059 --> 00:04:45,556 We gotta start taking these seriously as we should with 76 00:04:45,556 --> 00:04:47,511 every chemical we put into our bodies. 77 00:04:47,511 --> 00:04:49,689 You shouldn't assume it's safe and you shouldn't assume 78 00:04:49,689 --> 00:04:51,040 it's beneficial. 79 00:04:51,040 --> 00:04:53,675 Currently we don't know about the long term ethics 80 00:04:53,675 --> 00:04:55,691 of diet supplements. 81 00:04:55,691 --> 00:04:57,243 I'm a scientist. 82 00:04:57,243 --> 00:05:01,669 I'm also a father and I want to know how do I do the best 83 00:05:01,669 --> 00:05:06,419 for my son, and one day, might he be taking vitamin pills 84 00:05:07,644 --> 00:05:08,477 to Mars? 85 00:05:09,596 --> 00:05:12,763 (engine blasting off) 86 00:05:13,741 --> 00:05:16,485 Across the word, some experts claim that taking vitamins 87 00:05:16,485 --> 00:05:19,558 can be life savers, whereas others argue that it's just 88 00:05:19,558 --> 00:05:22,882 a waste of time or even dangerous, so how are we supposed 89 00:05:22,882 --> 00:05:26,130 to know whether the take them or not? 90 00:05:26,130 --> 00:05:28,880 (dramatic music) 91 00:05:30,000 --> 00:05:36,074 Everyone is intimidated by a shark. Become a Card Shark AMERICASCARDROOM.COM 92 00:05:37,367 --> 00:05:40,450 (train bell ringing) 93 00:05:48,080 --> 00:05:52,381 Over a billion of us take at least one vitamin or supplement 94 00:05:52,381 --> 00:05:54,454 hoping to keep as healthy as possible 95 00:05:54,454 --> 00:05:56,434 for as long as possible, 96 00:05:56,434 --> 00:06:00,495 but most of us know nothing about them. 97 00:06:00,495 --> 00:06:04,032 This ordinary meal contains almost every single essential 98 00:06:04,032 --> 00:06:05,894 vitamin and nutrient we need. 99 00:06:05,894 --> 00:06:08,728 There are vitamins A, B, and K in the lettuce, lots of 100 00:06:08,728 --> 00:06:12,438 vitamin Bs in the chicken, vitamin C in the tomato, K in 101 00:06:12,438 --> 00:06:15,886 the cucumber, vitamin D in the egg yolk? 102 00:06:15,886 --> 00:06:18,076 There are even vitamins in your coffee and that's before 103 00:06:18,076 --> 00:06:19,615 you add the milk. 104 00:06:19,615 --> 00:06:23,684 In fact, this meal contains every single one of these but 105 00:06:23,684 --> 00:06:26,667 what are these exactly and what are they doing to 106 00:06:26,667 --> 00:06:30,417 our bodies, and how much do we actually need? 107 00:06:33,640 --> 00:06:36,798 Around 100 years ago, we didn't even know that vitamins 108 00:06:36,798 --> 00:06:37,631 existed. 109 00:06:38,609 --> 00:06:43,609 We knew we needed protein, carbohydrate, fat, and minerals 110 00:06:44,042 --> 00:06:46,982 and some suspected there were other vital substances 111 00:06:46,982 --> 00:06:49,399 in food but they had no name. 112 00:06:51,761 --> 00:06:54,620 And then in 1911, a Polish chemist began some important 113 00:06:54,620 --> 00:06:58,443 experiments with some unfortunate pigeons and he changed 114 00:06:58,443 --> 00:07:00,490 the course of history. 115 00:07:00,490 --> 00:07:02,990 His name was Dr. Casimir Funk. 116 00:07:04,117 --> 00:07:09,117 ♪ It must have been some flash of inspiration ♪ 117 00:07:09,655 --> 00:07:14,655 ♪ Rendered scientifically precise ♪ 118 00:07:15,397 --> 00:07:20,397 ♪ Conclusions that he drew from observation ♪ 119 00:07:21,576 --> 00:07:26,576 ♪ Feeding pigeons different types of rice ♪ 120 00:07:26,698 --> 00:07:29,688 ♪ He said some get sick ♪ 121 00:07:29,688 --> 00:07:32,431 ♪ Some get well ♪ 122 00:07:32,431 --> 00:07:37,431 ♪ It ain't no germ or virus, not as far as I can tell ♪ 123 00:07:38,013 --> 00:07:43,013 ♪ There's something else inside that feed ♪ 124 00:07:43,796 --> 00:07:46,396 ♪ It isn't something bad they get ♪ 125 00:07:46,396 --> 00:07:49,474 ♪ It's something good they need ♪ 126 00:07:49,474 --> 00:07:53,920 ♪ Thank you Dr. Funk ♪ 127 00:07:53,920 --> 00:07:57,587 ♪ For helping us understand ♪ 128 00:07:59,121 --> 00:08:01,568 At the turn of the 20th century, millions of people were 129 00:08:01,568 --> 00:08:04,823 suffering from diseases rarely seen today, things like 130 00:08:04,823 --> 00:08:08,071 beri beri, pellagra, rickets, and scurvy. 131 00:08:08,071 --> 00:08:09,548 Now, the thinking at the time was that it was the 132 00:08:09,548 --> 00:08:12,859 presence of something bad that made us sick, germs and 133 00:08:12,859 --> 00:08:15,042 toxins were all the range. 134 00:08:15,042 --> 00:08:17,632 ♪ It all comes down to the (mumbles) aminos ♪ 135 00:08:17,632 --> 00:08:19,284 ♪ Casimir Funk is ♪ 136 00:08:19,284 --> 00:08:22,878 When Funk fed his pigeons white rice, starch, or sugar, 137 00:08:22,878 --> 00:08:24,211 they became ill. 138 00:08:25,357 --> 00:08:28,509 But fed brown rice, they recovered. 139 00:08:28,509 --> 00:08:31,378 So Funk wanted to identify the substance in the brown rice 140 00:08:31,378 --> 00:08:32,711 that cured them. 141 00:08:34,893 --> 00:08:37,095 Now, Funk didn't know where this mystery substance actually 142 00:08:37,095 --> 00:08:40,822 was but he invented a word to describe it, from the Latin 143 00:08:40,822 --> 00:08:44,440 vita, meaning life, and amine, containing nitrogen. 144 00:08:44,440 --> 00:08:46,831 Later, the E was dropped in English, so the word 145 00:08:46,831 --> 00:08:48,234 became vitamin. 146 00:08:48,234 --> 00:08:52,308 Dr. Funk invented a catchy word that captured a fresh idea. 147 00:08:52,308 --> 00:08:55,160 There was a new family of nutrients, the absence of which 148 00:08:55,160 --> 00:08:56,826 caused disease. 149 00:08:56,826 --> 00:08:59,314 Soon it became evident that they were not all amines, 150 00:08:59,314 --> 00:09:01,169 but the name stuck and the word vitamin 151 00:09:01,169 --> 00:09:04,752 became famous, taking on a life of its own. 152 00:09:08,435 --> 00:09:11,518 ♪ Thank you Dr. Funk ♪ 153 00:09:13,646 --> 00:09:17,373 Over the next few decades, all 13 vitamins were identified. 154 00:09:17,373 --> 00:09:20,697 Soon, they were synthesized and turned into pills. 155 00:09:20,697 --> 00:09:23,787 Little did Dr. Funk realize, his vitamins would spawn 156 00:09:23,787 --> 00:09:27,035 100 billion dollar a year industry. 157 00:09:27,035 --> 00:09:28,702 Vitamania had begun. 158 00:09:31,140 --> 00:09:34,450 ♪ Thank you Dr. Funk ♪ 159 00:09:34,450 --> 00:09:38,200 ♪ Casimir Funk, Casimir Funk ♪ 160 00:09:40,461 --> 00:09:43,044 (lively music) 161 00:09:45,288 --> 00:09:48,099 I've come here to one of the largest nutritional trade 162 00:09:48,099 --> 00:09:49,349 shows on Earth. 163 00:09:58,677 --> 00:10:02,106 They're expecting tens of thousands of people, all buying 164 00:10:02,106 --> 00:10:05,070 and selling the latest and greatest in vitamins and dietary 165 00:10:05,070 --> 00:10:06,070 supplements. 166 00:10:07,115 --> 00:10:09,615 I want to see what's on offer. 167 00:10:14,284 --> 00:10:16,879 After about four days, you really feel all the brain 168 00:10:16,879 --> 00:10:20,466 health benefits, so cognitive support, memory support, 169 00:10:20,466 --> 00:10:22,260 amazing sleep. 170 00:10:22,260 --> 00:10:25,404 Historically, silver's known to be antiviral, antifungal, 171 00:10:25,404 --> 00:10:28,268 antibacterial to build your immune system by potentiating 172 00:10:28,268 --> 00:10:29,553 your white blood cell count. 173 00:10:29,553 --> 00:10:32,836 They're organic botanical source vitamins and instead of 174 00:10:32,836 --> 00:10:35,568 putting them in isolated sugar syrups, we put them 175 00:10:35,568 --> 00:10:36,651 in more food. 176 00:10:41,433 --> 00:10:44,352 Vitamins have managed to develop this halo around them 177 00:10:44,352 --> 00:10:48,307 where everything the word vitamin touches seems like it 178 00:10:48,307 --> 00:10:51,678 should be both miraculous and safe. 179 00:10:51,678 --> 00:10:53,721 Science journalist Catherine Price spent 180 00:10:53,721 --> 00:10:57,170 five years investigating vitamins. 181 00:10:57,170 --> 00:10:59,912 We tend to think of vitamins and supplements as this kind 182 00:10:59,912 --> 00:11:02,221 of home grown industry of people gathering herbs in their 183 00:11:02,221 --> 00:11:04,194 backyards and boiling oranges 184 00:11:04,194 --> 00:11:05,978 for vitamin C and it's actually 185 00:11:05,978 --> 00:11:08,145 a 40 billion dollar a year industry 186 00:11:08,145 --> 00:11:10,570 in the US and 100 billion dollars 187 00:11:10,570 --> 00:11:13,751 around the world and it's growing rapidly. 188 00:11:13,751 --> 00:11:15,864 Who is taking vitamins? 189 00:11:15,864 --> 00:11:17,636 More than half of Americans are taking some kind of 190 00:11:17,636 --> 00:11:22,329 supplement and ironically, that half is often the healthier 191 00:11:22,329 --> 00:11:25,171 half of the American population. 192 00:11:25,171 --> 00:11:27,350 You have to have a certain amount of awareness and interest 193 00:11:27,350 --> 00:11:30,904 in health to go out and buy these products. 194 00:11:30,904 --> 00:11:34,179 It has omega-369 and it's the only sauce of omega-7 195 00:11:34,179 --> 00:11:36,095 in the plant sauce world. 196 00:11:36,095 --> 00:11:39,400 All of our multi-vitamins have a base of omega-3 197 00:11:39,400 --> 00:11:43,281 fish oil, multi-vitamin as well as vitamins E12 and D3. 198 00:11:43,281 --> 00:11:46,674 C, D, E, all your B vitamins. 199 00:11:46,674 --> 00:11:49,651 Folic acid, you name it, it's in there. 200 00:11:49,651 --> 00:11:53,192 Most vitamins are self prescribed. 201 00:11:53,192 --> 00:11:56,150 They're not recommended by a doctor. 202 00:11:56,150 --> 00:11:57,824 So we should know that the biggest category for 203 00:11:57,824 --> 00:12:00,331 vitamins is multi-vitamins. 204 00:12:00,331 --> 00:12:03,379 Most of us, not all of us, have been taught from a young age 205 00:12:03,379 --> 00:12:05,754 they're something that you take just in case. 206 00:12:05,754 --> 00:12:07,914 Just in case you don't get enough fruits and vegetables 207 00:12:07,914 --> 00:12:10,912 from your diet, just take the multi-vitamin. 208 00:12:10,912 --> 00:12:12,790 And I think when you talk about vitamins, a big part of the 209 00:12:12,790 --> 00:12:14,746 psychology is hope. 210 00:12:14,746 --> 00:12:17,412 What you're looking at right here is a powdered magnesium 211 00:12:17,412 --> 00:12:18,711 citrate formula. 212 00:12:18,711 --> 00:12:21,669 We have an adrenal fatigue formula that has a very heavy 213 00:12:21,669 --> 00:12:23,335 B-complex. 214 00:12:23,335 --> 00:12:25,773 These are biological response modifiers. 215 00:12:25,773 --> 00:12:28,121 Are there like vitamins in here? 216 00:12:28,121 --> 00:12:29,783 Yeah, there's-- 217 00:12:29,783 --> 00:12:30,841 Some? 218 00:12:30,841 --> 00:12:34,710 Then, Catherine told me something I found staggering. 219 00:12:34,710 --> 00:12:36,755 How are vitamins regulated? 220 00:12:36,755 --> 00:12:38,711 Vitamins are not regulated the way that you would think 221 00:12:38,711 --> 00:12:40,468 they would be. 222 00:12:40,468 --> 00:12:43,514 Technically, the FDA is in control of them, but all of 223 00:12:43,514 --> 00:12:46,536 these products around us, all of the 85 thousand dietary 224 00:12:46,536 --> 00:12:49,356 supplement products on the shelves, 225 00:12:49,356 --> 00:12:52,446 none of them are required to be tested for safety 226 00:12:52,446 --> 00:12:55,235 or for efficacy before they're sold. 227 00:12:55,235 --> 00:12:56,585 So not at all. 228 00:12:56,585 --> 00:13:00,371 The FDA cannot require any of these companies to test them 229 00:13:00,371 --> 00:13:02,658 to make sure they do what they say or that they're not 230 00:13:02,658 --> 00:13:04,794 going to hurt you. 231 00:13:04,794 --> 00:13:07,073 And it's not just the US. 232 00:13:07,073 --> 00:13:10,437 In Australia and Europa as well, they're not required to be 233 00:13:10,437 --> 00:13:12,937 tested for safety before sale. 234 00:13:13,909 --> 00:13:16,591 But what about kid's vitamins? 235 00:13:16,591 --> 00:13:18,542 Children's vitamins are regulated the same way adult 236 00:13:18,542 --> 00:13:20,471 vitamins are, which is to say they're not required to be 237 00:13:20,471 --> 00:13:23,815 tested for safety or for efficacy before they're sold. 238 00:13:23,815 --> 00:13:26,323 So what you're giving your child doesn't have 239 00:13:26,323 --> 00:13:27,406 to be tested? 240 00:13:28,785 --> 00:13:29,702 So nothing? 241 00:13:30,572 --> 00:13:31,405 No. 242 00:13:35,985 --> 00:13:39,189 Never in history have we had the ability to manipulate 243 00:13:39,189 --> 00:13:42,573 our nutrition in such extraordinary ways, but how do we know 244 00:13:42,573 --> 00:13:45,752 if what we're doing is a good idea or not? 245 00:13:45,752 --> 00:13:49,091 I'm a scientist, my background is in physics, and so I have 246 00:13:49,091 --> 00:13:51,723 a bias towards evidence and I'm skeptical of some of the 247 00:13:51,723 --> 00:13:54,464 marketing claims made here, but I'm trying to keep an open 248 00:13:54,464 --> 00:13:57,985 mind, after all, there have been at least 10 Nobel prizes 249 00:13:57,985 --> 00:14:01,775 awarded for vitamin science, so I'm in search of a deeper 250 00:14:01,775 --> 00:14:05,168 understanding and I want to start with the basics, like 251 00:14:05,168 --> 00:14:07,335 what exactly is a vitamin? 252 00:14:09,268 --> 00:14:12,018 (peaceful music) 253 00:14:15,615 --> 00:14:19,865 Vitamins are chemicals that are essential for life. 254 00:14:21,598 --> 00:14:25,015 Without them, we get sick and we can die. 255 00:14:28,945 --> 00:14:32,421 Our bodies can't make vitamins by themselves, so we usually 256 00:14:32,421 --> 00:14:35,017 get them from our food. 257 00:14:35,017 --> 00:14:38,141 So far, 13 vitamins have been identified and although they 258 00:14:38,141 --> 00:14:41,965 share a name, these are very different molecules and they 259 00:14:41,965 --> 00:14:44,450 do very different things. 260 00:14:44,450 --> 00:14:47,033 (bright music) 261 00:14:48,670 --> 00:14:51,872 ♪ Hey, hey, I'm vitamin A ♪ 262 00:14:51,872 --> 00:14:55,896 ♪ The first vitamin on display ♪ 263 00:14:55,896 --> 00:14:59,829 ♪ When you open your eyes, I help you see the light ♪ 264 00:14:59,829 --> 00:15:04,279 ♪ When the germs arise, I'm gonna teach you to fight ♪ 265 00:15:04,279 --> 00:15:07,608 ♪ Here we come, we're the vitamin Bs ♪ 266 00:15:07,608 --> 00:15:10,926 ♪ We're a great big family ♪ 267 00:15:10,926 --> 00:15:14,297 ♪ So much energy you can gain ♪ 268 00:15:14,297 --> 00:15:17,946 ♪ For your metabolism and your genes and your brain ♪ 269 00:15:17,946 --> 00:15:22,946 ♪ One two three five six seven nine 12, the Bs ♪ 270 00:15:23,646 --> 00:15:27,204 ♪ Howdy folks, they call me vitamin C ♪ 271 00:15:27,204 --> 00:15:28,446 ♪ Vitamin C ♪ 272 00:15:28,446 --> 00:15:33,446 ♪ I'm a healer and protector and I can almost guarantee ♪ 273 00:15:34,052 --> 00:15:39,052 ♪ You're impervious to scurvy if you get your share of me ♪ 274 00:15:39,906 --> 00:15:44,906 ♪ Vitamin C, vitamin C, vitamin C ♪ 275 00:15:47,157 --> 00:15:52,157 ♪ I think it's unfair, it almost seems cruel ♪ 276 00:15:54,378 --> 00:15:59,378 ♪ To come from the sun and still be so cool ♪ 277 00:16:01,600 --> 00:16:05,645 ♪ Warmest regards, vitamin D ♪ 278 00:16:05,645 --> 00:16:08,170 ♪ Yeah ♪ 279 00:16:08,170 --> 00:16:13,170 ♪ Well, babe I know sometimes it's hard to recognize ♪ 280 00:16:13,762 --> 00:16:18,762 ♪ When you need some help to antioxidize ♪ 281 00:16:19,222 --> 00:16:23,584 ♪ So stop those radicals from running wild and free ♪ 282 00:16:23,584 --> 00:16:28,584 ♪ Look to me, E ♪ 283 00:16:29,718 --> 00:16:32,481 ♪ Hey I'm K, there's something I'd say, I keep your body ♪ 284 00:16:32,481 --> 00:16:34,679 ♪ Rocking in a critical way ♪ 285 00:16:34,679 --> 00:16:37,430 ♪ A well known cornerstone for your blood and bone ♪ 286 00:16:37,430 --> 00:16:40,073 ♪ I can't do it alone, you need all the crew, the whole ♪ 287 00:16:40,073 --> 00:16:43,037 ♪ Retinue, props to do because that's how you grew ♪ 288 00:16:43,037 --> 00:16:45,682 ♪ And that's what you need to get through the day, ♪ 289 00:16:45,682 --> 00:16:49,849 ♪ Talk about vitamins A through K ♪ 290 00:16:55,971 --> 00:16:58,967 The 13 vitamins can be divided into two teams, the water 291 00:16:58,967 --> 00:17:02,991 soluble team consisting of all the B vitamins and vitamin C 292 00:17:02,991 --> 00:17:04,224 and the fat soluble team, 293 00:17:04,224 --> 00:17:07,746 consisting of A, D, E, and K, ADEK. 294 00:17:07,746 --> 00:17:10,006 So why does this matter? 295 00:17:10,006 --> 00:17:12,838 Well, we can get rid of excess water soluble vitamins 296 00:17:12,838 --> 00:17:15,566 in our urine, but the fat soluble ones are stored in our 297 00:17:15,566 --> 00:17:18,808 livers and fatty tissue, so they're the ones that can 298 00:17:18,808 --> 00:17:21,475 build up easily to toxic levels. 299 00:17:23,658 --> 00:17:26,440 What does a food data miner do? 300 00:17:26,440 --> 00:17:28,406 So essentially, I'm looking at all 301 00:17:28,406 --> 00:17:31,807 these different kind of (mumbles) foods. 302 00:17:31,807 --> 00:17:33,693 Someone who's an expert in the vitamins in our 303 00:17:33,693 --> 00:17:36,776 food is dietician Dr. Yasmine Probst. 304 00:17:38,441 --> 00:17:42,777 If I could see the amount of vitamins that I need every day, 305 00:17:42,777 --> 00:17:44,123 it would look like this? 306 00:17:44,123 --> 00:17:44,956 That's right, 307 00:17:44,956 --> 00:17:45,789 that's a very close representation 308 00:17:45,789 --> 00:17:48,328 to what we need, they're tiny. 309 00:17:48,328 --> 00:17:49,523 There's hardly anything here. 310 00:17:49,523 --> 00:17:50,684 Exactly. 311 00:17:50,684 --> 00:17:52,044 They're a speck on this plate here. 312 00:17:52,044 --> 00:17:54,633 Yeah, like vitamin D there, nearly invisible. 313 00:17:54,633 --> 00:17:56,064 Yeah, exactly. 314 00:17:56,064 --> 00:17:59,390 It just looks like a few pinches of salt or spice. 315 00:17:59,390 --> 00:18:02,050 Yeah, so it might be about the size of say, a poppy seed 316 00:18:02,050 --> 00:18:06,714 or something really tiny that people see on a regular basis. 317 00:18:06,714 --> 00:18:09,559 So in order to get all the vitamins I need in a day, this 318 00:18:09,559 --> 00:18:11,400 is the food I need to eat? 319 00:18:11,400 --> 00:18:14,587 That's right, that's right, not very many foods at all. 320 00:18:14,587 --> 00:18:18,011 But I would eat this in one meal, this looks like dinner 321 00:18:18,011 --> 00:18:19,338 and dessert to me. 322 00:18:19,338 --> 00:18:21,273 Well, this is the amount that you would need as an 323 00:18:21,273 --> 00:18:22,732 average adult male. 324 00:18:22,732 --> 00:18:25,134 Some people imagine you need to eat a giant mound 325 00:18:25,134 --> 00:18:27,875 of food, you know like a pile of spinach to get the vitamins 326 00:18:27,875 --> 00:18:31,114 that you need in a day, but it's really not that much. 327 00:18:31,114 --> 00:18:33,137 Well, I guess there's a little bit of confusion out there. 328 00:18:33,137 --> 00:18:35,317 People think that the amount of food that you need are 329 00:18:35,317 --> 00:18:38,352 these really big numbers but it's really not that much 330 00:18:38,352 --> 00:18:41,054 and it's more about eating the right foods in the right 331 00:18:41,054 --> 00:18:44,686 balance so that you get the right nutrients that you need. 332 00:18:44,686 --> 00:18:47,693 One carrot gives me all I would need of vitamin A. 333 00:18:47,693 --> 00:18:51,129 That's right, one medium carrot. 334 00:18:51,129 --> 00:18:53,918 When we eat a carrot, vitamins are released 335 00:18:53,918 --> 00:18:58,751 into the bloodstream, beginning a complex molecular dance. 336 00:18:59,593 --> 00:19:00,843 Take vitamin A. 337 00:19:01,811 --> 00:19:05,956 Our body makes it from a plant chemical called beta carotene 338 00:19:05,956 --> 00:19:09,637 and transforms it into forms of vitamin A that are essential 339 00:19:09,637 --> 00:19:14,637 for sight, immune function, and even how an embryo develops. 340 00:19:16,439 --> 00:19:20,523 Each of the vitamins trigger amazing chemical reactions, 341 00:19:20,523 --> 00:19:24,606 and together, they impact every part of our body. 342 00:19:25,610 --> 00:19:30,523 We can't hear, smell, think, touch, taste, breathe 343 00:19:30,523 --> 00:19:33,001 without these 13 vitamins, 344 00:19:33,001 --> 00:19:36,751 they don't just keep us alive, they are life. 345 00:19:38,417 --> 00:19:42,384 And when it's all working well, it's a wonder. 346 00:19:42,384 --> 00:19:47,384 But when we don't have enough, when there are deficiencies, 347 00:19:47,541 --> 00:19:49,541 the body's systems fail. 348 00:19:54,829 --> 00:19:58,106 I noticed that I was getting very tired. 349 00:19:58,106 --> 00:20:01,105 Weakness, blood was coming out through the side of the 350 00:20:01,105 --> 00:20:04,855 teeth and stuff and it started getting worse. 351 00:20:07,475 --> 00:20:12,223 And then I also noticed that I was sleeping a lot. 352 00:20:12,223 --> 00:20:17,223 Now, I'm talking about from six in the afternoon all the way 353 00:20:18,251 --> 00:20:21,418 'til 10 in the morning, I mean, a lot. 354 00:20:22,770 --> 00:20:25,884 And so that kind of scared me, so I knew something 355 00:20:25,884 --> 00:20:30,134 was wrong, so that's why I'm glad I went and I seen 356 00:20:31,244 --> 00:20:32,654 Dr. Churchill. 357 00:20:32,654 --> 00:20:35,321 (intense music) 358 00:20:42,464 --> 00:20:45,128 Sonny Lopez had a disease that no one had 359 00:20:45,128 --> 00:20:49,696 thought to look for, let alone test for for decades, 360 00:20:49,696 --> 00:20:52,113 and he wasn't the first case. 361 00:20:55,073 --> 00:21:00,073 So the first patient came in with painful, bruisy rash 362 00:21:00,252 --> 00:21:04,296 on both of his legs and general joint pains and fatigue 363 00:21:04,296 --> 00:21:08,988 and other systems and he had been treated for what they 364 00:21:08,988 --> 00:21:12,425 thought was an infection of the legs with no improvement, 365 00:21:12,425 --> 00:21:16,576 people were looking for blood clots and other things and all 366 00:21:16,576 --> 00:21:19,873 of the tests were coming up negative. 367 00:21:19,873 --> 00:21:23,040 Someone thought to ask about his diet. 368 00:21:24,345 --> 00:21:27,774 They found that he had been eating nothing but white bread 369 00:21:27,774 --> 00:21:31,879 and American cheese for the last several years. 370 00:21:31,879 --> 00:21:36,002 No fruits, no vegetables, nothing that would provide you 371 00:21:36,002 --> 00:21:41,002 with the basic level of nutrition that you would need. 372 00:21:41,084 --> 00:21:43,975 Then, with that kind of nutritional problem, maybe we should 373 00:21:43,975 --> 00:21:48,250 check some vitamin levels and his vitamin C level came back 374 00:21:48,250 --> 00:21:51,809 at absolutely undetectable, level of zero. 375 00:21:51,809 --> 00:21:54,282 Dr. Eric Churchill was stunned. 376 00:21:54,282 --> 00:21:57,092 He realized the patients had a disease common more than 377 00:21:57,092 --> 00:21:59,675 100 years ago, they had scurvy. 378 00:22:01,643 --> 00:22:03,944 This is something you hear about with pirates in the 379 00:22:03,944 --> 00:22:07,414 18th century, it's just not a disease that we thought 380 00:22:07,414 --> 00:22:08,997 people had anymore. 381 00:22:10,011 --> 00:22:12,761 (dramatic music) 382 00:22:19,680 --> 00:22:22,666 Scurvy was absolutely devastating 383 00:22:22,666 --> 00:22:27,066 it's been estimated that between the late 1400s and early 384 00:22:27,066 --> 00:22:30,862 1800s, two million sailors perished as a result 385 00:22:30,862 --> 00:22:32,195 of this disease. 386 00:22:33,185 --> 00:22:35,275 It's harder than I expected. 387 00:22:35,275 --> 00:22:37,942 Medical historian Dr. John Waller has studied the links 388 00:22:37,942 --> 00:22:39,942 between scurvy and diet. 389 00:22:41,261 --> 00:22:43,820 So this is a typical daily ration for a sailor in the 390 00:22:43,820 --> 00:22:48,820 royal navy in the 18th century, about a pound of very hard 391 00:22:48,915 --> 00:22:50,516 ship's biscuit. 392 00:22:50,516 --> 00:22:52,813 Then they would get something like half a pint 393 00:22:52,813 --> 00:22:53,980 of dried peas. 394 00:22:55,033 --> 00:22:59,704 Then salted meat, and it would be washed down with something 395 00:22:59,704 --> 00:23:01,324 like a gallon of beer every day. 396 00:23:01,324 --> 00:23:04,156 But there was something missing from their diet. 397 00:23:04,156 --> 00:23:07,079 Yeah, there's something very, very significant missing. 398 00:23:07,079 --> 00:23:09,746 And that of course is vitamin C. 399 00:23:10,915 --> 00:23:12,715 The thought that certain foods might 400 00:23:12,715 --> 00:23:14,859 cure scurvy wasn't a new one. 401 00:23:14,859 --> 00:23:18,731 It was an old idea that had been discovered and forgotten 402 00:23:18,731 --> 00:23:19,648 many times. 403 00:23:20,866 --> 00:23:25,393 Every so often, somebody would try citrus fruits. 404 00:23:25,393 --> 00:23:28,079 The sailors would make what appeared to be a miraculous 405 00:23:28,079 --> 00:23:32,079 recovery, but it never became standard practice. 406 00:23:33,292 --> 00:23:34,867 So how did they eventually figure out 407 00:23:34,867 --> 00:23:36,375 how to cure scurvy? 408 00:23:36,375 --> 00:23:38,315 It happened very gradually, but there were a few 409 00:23:38,315 --> 00:23:40,560 really critical moments. 410 00:23:40,560 --> 00:23:44,893 One of them took place in 1747, when a Scottish born 411 00:23:45,961 --> 00:23:50,260 ship's surgeon ran what is the first controlled 412 00:23:50,260 --> 00:23:52,927 clinical trial in human history. 413 00:23:54,742 --> 00:23:58,069 Dr. James Lind had seen the horrors of scurvy 414 00:23:58,069 --> 00:23:59,417 firsthand. 415 00:23:59,417 --> 00:24:02,682 Usually the ship's surgeon would try a range of supposed 416 00:24:02,682 --> 00:24:07,461 remedies and hope for the best, but Lind came up with a 417 00:24:07,461 --> 00:24:08,378 novel idea. 418 00:24:09,658 --> 00:24:14,177 He took 12 men with scurvy and split them into pairs. 419 00:24:14,177 --> 00:24:16,490 Each pair was given ship's rations plus one of the 420 00:24:16,490 --> 00:24:19,450 supposed cures of the time. 421 00:24:19,450 --> 00:24:22,950 Cider, vinegar, seawater, something called 422 00:24:24,385 --> 00:24:29,385 "elixir of vitriol" made from sulfuric acid, a concoction 423 00:24:29,602 --> 00:24:33,352 of garlic and mustard, or oranges and lemons. 424 00:24:36,920 --> 00:24:40,140 The two sailors who had been receiving the citrus fruits 425 00:24:40,140 --> 00:24:43,025 had made a really remarkable recovery. 426 00:24:43,025 --> 00:24:47,497 Now, the two who had received cider were somewhat improved. 427 00:24:47,497 --> 00:24:50,864 The rest, they had continued to deteriorate and they were 428 00:24:50,864 --> 00:24:53,139 fast on the way to dying. 429 00:24:53,139 --> 00:24:57,478 So this experiment had allowed him to arrive at a really 430 00:24:57,478 --> 00:25:02,172 clear conclusion, that fresh fruits and vegetables 431 00:25:02,172 --> 00:25:05,757 really can be used to cure scurvy. 432 00:25:05,757 --> 00:25:08,589 How significant would you consider Lind's experiment? 433 00:25:08,589 --> 00:25:11,602 There's no question that this single discovery saved 434 00:25:11,602 --> 00:25:15,360 millions of lives, but there's a broader and every bit as 435 00:25:15,360 --> 00:25:20,183 enduring effect of Lind's work and that is the way in which 436 00:25:20,183 --> 00:25:23,988 controlled clinical trial eventually becomes orthodoxy 437 00:25:23,988 --> 00:25:24,988 in medicine. 438 00:25:26,124 --> 00:25:29,735 It's a species altering development. 439 00:25:29,735 --> 00:25:33,060 Humans had unlocked the way to identify 440 00:25:33,060 --> 00:25:34,810 what cures will work. 441 00:25:36,272 --> 00:25:39,104 When Lind goes to publish his findings a few years later, 442 00:25:39,104 --> 00:25:42,405 he buries the information in a few paragraphs 200 pages 443 00:25:42,405 --> 00:25:44,844 into his 400 page book. 444 00:25:44,844 --> 00:25:47,442 It's as though not even Lind realizes the significance 445 00:25:47,442 --> 00:25:50,146 of his own discovery, and it may have been forgotten 446 00:25:50,146 --> 00:25:53,082 yet again if not for the work of a young doctor Gilbert 447 00:25:53,082 --> 00:25:56,567 Blain who manages to convince the British navy to supply 448 00:25:56,567 --> 00:25:58,733 lemon juice to its sailors. 449 00:25:58,733 --> 00:26:00,150 The year is 1795. 450 00:26:01,755 --> 00:26:05,117 That's one year after Lind's death and 48 years after his 451 00:26:05,117 --> 00:26:07,338 historic experiment. 452 00:26:07,338 --> 00:26:10,171 (whimsical music) 453 00:26:11,323 --> 00:26:15,504 With lemons and later limes as their secret weapon, 454 00:26:15,504 --> 00:26:20,140 the British navy emerged as the strongest on the globe. 455 00:26:20,140 --> 00:26:24,410 The supply of fruit shaped the destiny of nations, allowing 456 00:26:24,410 --> 00:26:28,811 us to venture out across the seas, to live and to thrive 457 00:26:28,811 --> 00:26:31,311 fueled by the right nutrition. 458 00:26:37,216 --> 00:26:40,502 But today, it seems that knowledge is being forgotten 459 00:26:40,502 --> 00:26:41,942 once again. 460 00:26:41,942 --> 00:26:43,647 How many people live here? 461 00:26:43,647 --> 00:26:45,389 I'd say about 15. 462 00:26:45,389 --> 00:26:47,142 And how long you been living here? 463 00:26:47,142 --> 00:26:48,809 Five years, Derek. 464 00:26:48,809 --> 00:26:50,571 That's a pretty long time. 465 00:26:50,571 --> 00:26:52,321 Yes, it is. 466 00:26:55,734 --> 00:26:57,688 This is my castle right here. 467 00:26:57,688 --> 00:26:58,521 Wow. 468 00:27:01,458 --> 00:27:04,854 This is my family, this is everybody I love. 469 00:27:04,854 --> 00:27:07,271 That's me back when I was 21. 470 00:27:08,523 --> 00:27:10,005 You had a lot of hair back then. 471 00:27:10,005 --> 00:27:12,705 Yes, that was back in the hippie days, you know? 472 00:27:12,705 --> 00:27:14,027 It's a beautiful family. 473 00:27:14,027 --> 00:27:14,860 Thanks. 474 00:27:16,110 --> 00:27:19,175 This is all the stuff, this is where I keep my cereal, 475 00:27:19,175 --> 00:27:21,175 my bread, peanut butter. 476 00:27:23,033 --> 00:27:26,541 Refrigerate down the hall here, come on, I'll show you. 477 00:27:26,541 --> 00:27:30,374 I like to eat burgers, hot dogs, sodas, cakes, 478 00:27:33,184 --> 00:27:36,818 bad cereals, I'm not gonna lie to you. 479 00:27:36,818 --> 00:27:38,815 I do eat a lot of sugar. 480 00:27:38,815 --> 00:27:42,565 When I have my coffee, 15 sugars, two creams. 481 00:27:44,968 --> 00:27:49,635 Many people who have difficulty affording food tend to 482 00:27:50,478 --> 00:27:54,061 go for food that is high fat, high calorie, 483 00:27:55,165 --> 00:27:57,089 and very filling. 484 00:27:57,089 --> 00:27:59,287 If you have a limited food budget, those are the meals 485 00:27:59,287 --> 00:28:02,933 that will fill you up and will satisfy you more than 486 00:28:02,933 --> 00:28:05,566 eating fruits and vegetables. 487 00:28:05,566 --> 00:28:08,712 Alright doc, how you been? Good, good. 488 00:28:08,712 --> 00:28:11,611 In Sonny's case, he has got a lot of other things to worry 489 00:28:11,611 --> 00:28:15,787 about and for him, making sure to eat enough fruits 490 00:28:15,787 --> 00:28:19,333 and vegetables is very far down on his list. 491 00:28:19,333 --> 00:28:21,539 I thought I had some kind of vicious disease and I was 492 00:28:21,539 --> 00:28:26,456 really, really scared, because that's an ugly word, scurvy. 493 00:28:27,682 --> 00:28:30,744 So once we had diagnosed Sonny with scurvy, 494 00:28:30,744 --> 00:28:34,214 the first thing we did was to give him vitamin C tablets 495 00:28:34,214 --> 00:28:38,086 to correct the deficiency, and then, at a later visit 496 00:28:38,086 --> 00:28:39,578 when he said he was having trouble getting those 497 00:28:39,578 --> 00:28:43,348 supplements, I took out my prescription pad and I wrote 498 00:28:43,348 --> 00:28:47,015 "One orange every day" and handed it to him. 499 00:28:48,788 --> 00:28:51,083 It turned out that Sonny was part of an 500 00:28:51,083 --> 00:28:53,500 extraordinary scurvy cluster. 501 00:28:54,362 --> 00:28:56,886 In the last five years, we've documented 30 cases 502 00:28:56,886 --> 00:28:59,974 of scurvy and as far as I'm aware, that's the largest 503 00:28:59,974 --> 00:29:03,400 collection of scurvy cases in the developed world outside 504 00:29:03,400 --> 00:29:07,389 of some exceptional circumstances like war or refugee 505 00:29:07,389 --> 00:29:09,054 situations. 506 00:29:09,054 --> 00:29:10,954 So is it just an issue of all these people with scurvy 507 00:29:10,954 --> 00:29:12,595 not eating enough? 508 00:29:12,595 --> 00:29:13,772 It's really not. 509 00:29:13,772 --> 00:29:17,206 It's about the quality of the food that you eat. 510 00:29:17,206 --> 00:29:19,811 Over half of the people that we diagnose with scurvy 511 00:29:19,811 --> 00:29:23,946 are actually obese and so they are getting enough calories 512 00:29:23,946 --> 00:29:28,755 in their diet but they are low quality, low nutrition 513 00:29:28,755 --> 00:29:33,292 calories, we use the phrase hypercaloric malnutrition 514 00:29:33,292 --> 00:29:35,964 one of the things about scurvy is that it's really not 515 00:29:35,964 --> 00:29:37,714 difficult to prevent. 516 00:29:38,562 --> 00:29:42,045 This is not a high nutritional bar to reach. 517 00:29:42,045 --> 00:29:44,614 And even something like a handful of ketchup packets 518 00:29:44,614 --> 00:29:48,897 a day contain enough vitamin C to keep you out of scurvy. 519 00:29:48,897 --> 00:29:51,457 Not that I recommend people get all of their vitamin C 520 00:29:51,457 --> 00:29:54,624 from ketchup packets, but it's enough. 521 00:29:56,186 --> 00:29:58,989 Surprisingly, the top vitamin C foods 522 00:29:58,989 --> 00:30:01,235 aren't all citrus. 523 00:30:01,235 --> 00:30:04,078 Kiwi fruit, strawberries, and red peppers are all 524 00:30:04,078 --> 00:30:05,161 rich sources. 525 00:30:09,176 --> 00:30:13,516 But vitamin C is fragile, it degrades with time. 526 00:30:13,516 --> 00:30:16,911 One study showed that left at room temperature, 75 percent 527 00:30:16,911 --> 00:30:21,161 of the vitamin C in an apple can be lost in a week. 528 00:30:22,788 --> 00:30:26,355 So just over time, the nutritional content is going down. 529 00:30:26,355 --> 00:30:29,665 Yeah, it's affected by heat, by light, by storage 530 00:30:29,665 --> 00:30:31,681 conditions, lots of different things. 531 00:30:31,681 --> 00:30:33,375 So what should you do if you want to maximize 532 00:30:33,375 --> 00:30:34,974 your nutrition? 533 00:30:34,974 --> 00:30:37,747 I think keep it fresh, keep it local. 534 00:30:37,747 --> 00:30:40,126 The sooner you pick it and consume it, that's probably 535 00:30:40,126 --> 00:30:40,959 the best. 536 00:30:44,772 --> 00:30:47,372 Fascination with the power of vitamin C 537 00:30:47,372 --> 00:30:50,530 led scientists to isolate it and determine its 538 00:30:50,530 --> 00:30:52,873 chemical structure. 539 00:30:52,873 --> 00:30:56,206 In 1937, this work one two Nobel prizes. 540 00:30:58,766 --> 00:31:01,497 And led to the world's first synthetic 541 00:31:01,497 --> 00:31:03,330 or artificial vitamin. 542 00:31:05,119 --> 00:31:07,038 So where do you think the vitamin C in your pills 543 00:31:07,038 --> 00:31:07,955 comes from? 544 00:31:12,562 --> 00:31:14,917 This is the last remaining manufacturing plant for 545 00:31:14,917 --> 00:31:17,554 vitamin C in the western world. 546 00:31:17,554 --> 00:31:21,098 The vast majority of vitamins produced today are synthetic. 547 00:31:21,098 --> 00:31:24,210 That is, they're man made in chemical factories, and in 548 00:31:24,210 --> 00:31:27,601 general, the goal is to duplicate the exact structure 549 00:31:27,601 --> 00:31:30,118 of the naturally occurring vitamins. 550 00:31:30,118 --> 00:31:32,903 Now, we'd hoped to show you how that's done here, 551 00:31:32,903 --> 00:31:35,329 but after 12 months of negations, we've not been able 552 00:31:35,329 --> 00:31:38,909 to film inside, so instead, to understand how to create 553 00:31:38,909 --> 00:31:42,576 a vitamin, we're gonna have to make our own. 554 00:31:44,078 --> 00:31:46,823 To build a vitamin, you need raw materials. 555 00:31:46,823 --> 00:31:49,490 (truck beeping) 556 00:31:51,057 --> 00:31:53,385 And believe it or not, at least eight vitamins can be 557 00:31:53,385 --> 00:31:56,669 synthetically created from fossil fuel products like 558 00:31:56,669 --> 00:31:57,502 coal tar. 559 00:32:00,500 --> 00:32:03,378 They contain components like acetone, found in nail 560 00:32:03,378 --> 00:32:07,536 polish remover, short chain alkanes, found in petrol, 561 00:32:07,536 --> 00:32:11,625 and various aromatic rings found in (mumbles). 562 00:32:11,625 --> 00:32:15,239 The idea is to rearrange these building blocks into more 563 00:32:15,239 --> 00:32:17,842 complex chemical compounds. 564 00:32:17,842 --> 00:32:22,472 Actually building vitamins, precision matters, as a single 565 00:32:22,472 --> 00:32:24,472 bond can alter function. 566 00:32:27,023 --> 00:32:31,603 Not all synthetic vitamins come from fossil fuels. 567 00:32:31,603 --> 00:32:35,853 For example, if you extract sugars from corn syrup. 568 00:32:38,174 --> 00:32:42,635 Ferment them with bacteria and add a chemical reaction, 569 00:32:42,635 --> 00:32:45,052 you have synthetic vitamin C. 570 00:32:46,896 --> 00:32:49,780 Most synthetic vitamins are chemically identical 571 00:32:49,780 --> 00:32:51,951 to the natural form, but without the fiber 572 00:32:51,951 --> 00:32:55,201 and micronutrients that come with food. 573 00:32:56,840 --> 00:33:00,199 The end result is a vitamin made not by a plant, 574 00:33:00,199 --> 00:33:01,449 but in a plant. 575 00:33:02,784 --> 00:33:05,284 (jazzy music) 576 00:33:06,864 --> 00:33:08,366 It's far more efficient and cheaper 577 00:33:08,366 --> 00:33:11,949 to produce vitamins on an industrial scale. 578 00:33:13,649 --> 00:33:16,512 Today, more than 80 percent of the world's vitamin C is 579 00:33:16,512 --> 00:33:19,641 made in China, and it's pretty hard to work out where all 580 00:33:19,641 --> 00:33:22,429 of the raw materials for vitamins come from but most 581 00:33:22,429 --> 00:33:27,429 are produced unquestionably like this, synthetically. 582 00:33:27,476 --> 00:33:29,835 And then they're sent out across the globe to manufacturing 583 00:33:29,835 --> 00:33:33,847 plants, ready to be turned into vitamin pills. 584 00:33:33,847 --> 00:33:36,347 (jazzy music) 585 00:33:47,449 --> 00:33:50,888 Here in Australia, manufacturers are required to test 586 00:33:50,888 --> 00:33:54,543 raw materials on arrival, to ensure the product is what 587 00:33:54,543 --> 00:33:56,293 it says on the label. 588 00:33:59,226 --> 00:34:01,809 Then, the manufacturing begins. 589 00:34:15,159 --> 00:34:18,032 The raw vitamin material is blended with additives 590 00:34:18,032 --> 00:34:21,052 and binding agents, a different recipe 591 00:34:21,052 --> 00:34:23,052 for a different product. 592 00:34:25,106 --> 00:34:28,472 Given the amount of vitamin needed is generally tiny, 593 00:34:28,472 --> 00:34:32,099 what makes up the rest of the pill? 594 00:34:32,099 --> 00:34:34,999 Well, inactive materials like cellulose, sugars, 595 00:34:34,999 --> 00:34:38,378 or rice flour are often added to provide bulk and to 596 00:34:38,378 --> 00:34:41,461 help the tablets dissolve in the gut. 597 00:34:43,417 --> 00:34:46,403 Colors and flavors can also be added to make the tablets 598 00:34:46,403 --> 00:34:47,653 more palatable. 599 00:34:50,361 --> 00:34:53,045 The manufacturing process is similar for most synthetic 600 00:34:53,045 --> 00:34:57,212 vitamins, depending on the end product being made. 601 00:35:00,739 --> 00:35:04,231 Thousands of generic looking pills then fill containers 602 00:35:04,231 --> 00:35:07,731 and the distinctive packaging takes place. 603 00:35:10,179 --> 00:35:12,396 The vitamins are now branded and they're ready 604 00:35:12,396 --> 00:35:13,896 to hit the market. 605 00:35:21,432 --> 00:35:24,076 It's interesting, if vitamin manufacturers here want to 606 00:35:24,076 --> 00:35:27,426 claim "made in Australia," by law, none of the raw 607 00:35:27,426 --> 00:35:30,593 ingredients actually have to come from this country. 608 00:35:30,593 --> 00:35:32,461 And if you want to claim your product is natural, 609 00:35:32,461 --> 00:35:34,910 well, most of the regulators worldwide haven't defined 610 00:35:34,910 --> 00:35:37,951 what natural means, and so it can say natural on the label 611 00:35:37,951 --> 00:35:41,118 and yet contain synthetic ingredients. 612 00:35:42,891 --> 00:35:44,857 But what if you've never taken a vitamin pill 613 00:35:44,857 --> 00:35:46,400 in your life? 614 00:35:46,400 --> 00:35:48,867 You might think this entire vitamin manufacturing process 615 00:35:48,867 --> 00:35:52,831 is irrelevant to you, but then, you'd be wrong. 616 00:35:52,831 --> 00:35:55,453 It turns out even if you're not popping vitamin pills, 617 00:35:55,453 --> 00:35:58,650 chances are you are ingesting synthetic vitamins because 618 00:35:58,650 --> 00:36:03,400 in at least 95 nations, they're being added to your food. 619 00:36:06,220 --> 00:36:07,803 Eat Wonder Bread! 620 00:36:08,658 --> 00:36:11,096 You want to grow bigger and stronger, don't you? 621 00:36:11,096 --> 00:36:12,443 Golly, sure! 622 00:36:12,443 --> 00:36:13,494 Okay! 623 00:36:13,494 --> 00:36:16,357 A sandwich daily and two slices of Wonder Bread every meal 624 00:36:16,357 --> 00:36:18,863 give you eight elements you need. 625 00:36:18,863 --> 00:36:20,952 Around half the countries on Earth allow the 626 00:36:20,952 --> 00:36:25,002 addition of synthetic vitamins to common food products. 627 00:36:25,002 --> 00:36:27,483 It's called fortification. 628 00:36:27,483 --> 00:36:30,724 That's why you can help yourself grow bigger and stronger 629 00:36:30,724 --> 00:36:32,900 eight ways with Wonder Bread. 630 00:36:32,900 --> 00:36:35,479 So be sure to eat Wonder Bread! 631 00:36:35,479 --> 00:36:38,062 (lively music) 632 00:36:42,302 --> 00:36:44,912 In places like the US and Australia, fortifying 633 00:36:44,912 --> 00:36:48,662 bread flour and margarine is required by law. 634 00:36:51,096 --> 00:36:54,292 And companies often decide to add vitamins, mostly from 635 00:36:54,292 --> 00:36:55,375 the B family. 636 00:36:58,017 --> 00:37:00,629 The B vitamins are sometimes called the pep vitamins, 637 00:37:00,629 --> 00:37:02,402 they help our bodies produce energy and assist 638 00:37:02,402 --> 00:37:03,990 in cell development. 639 00:37:03,990 --> 00:37:06,924 Now, they're all water soluble, like vitamin C, which means 640 00:37:06,924 --> 00:37:09,409 our bodies don't store them, so we have to replenish 641 00:37:09,409 --> 00:37:10,326 them often. 642 00:37:11,369 --> 00:37:14,967 Their discovery and synthesis took over 50 years and led 643 00:37:14,967 --> 00:37:16,634 to six Nobel prizes. 644 00:37:17,476 --> 00:37:20,143 (factory music) 645 00:37:28,416 --> 00:37:31,777 One of the vitamins added to bread is B9, better known 646 00:37:31,777 --> 00:37:35,842 as folate, so why is it being added to my bread? 647 00:37:35,842 --> 00:37:38,425 (all shouting) 648 00:37:54,756 --> 00:37:57,924 At 29, Kim Robins is an international wheelchair 649 00:37:57,924 --> 00:37:59,257 basketball star. 650 00:38:04,633 --> 00:38:08,216 He tours the world, playing professionally. 651 00:38:14,748 --> 00:38:18,605 His body and entire life has been shaped by the power 652 00:38:18,605 --> 00:38:19,438 of folate. 653 00:38:20,532 --> 00:38:23,449 (applause, cheers) 654 00:38:26,063 --> 00:38:30,269 Kim was born with a hemangioma on his back 655 00:38:30,269 --> 00:38:33,760 in the middle of his shoulder blades. 656 00:38:33,760 --> 00:38:38,427 It was a legion which looked a bit like a red birthmark. 657 00:38:39,872 --> 00:38:44,039 We were assured at birth that everything was okay. 658 00:38:52,600 --> 00:38:57,229 And it wasn't until he was six months when flags started 659 00:38:57,229 --> 00:39:00,512 to be raised that perhaps he wasn't meeting all of 660 00:39:00,512 --> 00:39:01,762 his milestones. 661 00:39:02,687 --> 00:39:05,080 After months of tests, Kim was diagnosed 662 00:39:05,080 --> 00:39:07,650 with a neural tube defect. 663 00:39:07,650 --> 00:39:10,641 Effectively, a whole in his spinal column which caused 664 00:39:10,641 --> 00:39:12,058 permanent damage. 665 00:39:14,646 --> 00:39:17,305 Part of my disability is that I have chronic back pain 666 00:39:17,305 --> 00:39:22,055 and that's in my lower back, so I get pain maybe 200, 250 667 00:39:23,099 --> 00:39:24,099 times a day. 668 00:39:25,298 --> 00:39:27,387 It's kind of like a back spasm. 669 00:39:27,387 --> 00:39:29,804 My brain's fully functioning. 670 00:39:31,129 --> 00:39:35,245 I guess it affects my leg function to some extent 671 00:39:35,245 --> 00:39:37,945 so I can walk, not super well, but I can walk 672 00:39:37,945 --> 00:39:39,540 a little bit. 673 00:39:39,540 --> 00:39:41,957 Neural tube defects like Kim's can be caused 674 00:39:41,957 --> 00:39:45,290 by the lack of folate long before birth. 675 00:39:50,288 --> 00:39:53,122 If you eat folate, it's the best kind of diet because 676 00:39:53,122 --> 00:39:57,856 it's actually found richly in leafy green vegetables, 677 00:39:57,856 --> 00:39:59,881 it's found in things like asparagus, it's found in 678 00:39:59,881 --> 00:40:03,930 strawberries, it's found in whole grains, so if you are 679 00:40:03,930 --> 00:40:06,918 eating fruits and vegetables, it's quite likely that you 680 00:40:06,918 --> 00:40:09,585 will have a diet rich in folate. 681 00:40:11,282 --> 00:40:15,418 Folate is very important for both DNA and RNA repair, 682 00:40:15,418 --> 00:40:19,116 but also for the rapid development and multiplication 683 00:40:19,116 --> 00:40:21,973 of cells which is what's happening in the fetus, 684 00:40:21,973 --> 00:40:24,676 so it's essential for that. 685 00:40:24,676 --> 00:40:27,332 Professor Fiona Stanley led the Australian arm 686 00:40:27,332 --> 00:40:30,135 of an international children's study that showed lack of 687 00:40:30,135 --> 00:40:33,609 folate in a mother's diet before she was pregnant could 688 00:40:33,609 --> 00:40:36,806 cause major defects in utero. 689 00:40:36,806 --> 00:40:40,428 If before a woman knows that she's pregnant, the fetus 690 00:40:40,428 --> 00:40:42,909 is starting to form all of its major organs and one of 691 00:40:42,909 --> 00:40:46,616 the earliest, by perhaps the seventh week is the 692 00:40:46,616 --> 00:40:51,616 neural tube which starts as an open little trough and then 693 00:40:52,239 --> 00:40:56,034 starts to zipper up and it zips up and down. 694 00:40:56,034 --> 00:40:59,172 I think of it like a zipper going down and as each link 695 00:40:59,172 --> 00:41:02,653 forms together, that's part of the neural tube forming 696 00:41:02,653 --> 00:41:05,078 and if it misses one link, that's where the neural tube 697 00:41:05,078 --> 00:41:06,411 defect would be. 698 00:41:07,296 --> 00:41:11,419 Mine is up between T2 and T6, which is quite high up and 699 00:41:11,419 --> 00:41:14,257 so my spinal cord's a little bit withered, so some 700 00:41:14,257 --> 00:41:17,697 messages get through and some messages don't 701 00:41:17,697 --> 00:41:20,138 By the time a woman knows she's pregnant, 702 00:41:20,138 --> 00:41:21,863 it can be too late. 703 00:41:21,863 --> 00:41:24,689 So scientists sought a way to get a form of folate into 704 00:41:24,689 --> 00:41:27,585 a food that everyone might eat. 705 00:41:27,585 --> 00:41:31,176 There were lots of debates about what staple food 706 00:41:31,176 --> 00:41:35,783 should be fortified, and of course the one that was 707 00:41:35,783 --> 00:41:38,252 suggested was flour, bread making flour because bread seems 708 00:41:38,252 --> 00:41:40,669 to be such a ubiquitous food. 709 00:41:42,266 --> 00:41:44,480 In 2009, Australian bread was fortified 710 00:41:44,480 --> 00:41:47,313 with folic acid, synthetic folate. 711 00:41:49,821 --> 00:41:53,986 It might be added to all white flour for bread making. 712 00:41:53,986 --> 00:41:57,738 It's the same in the US, Canada, and the UK. 713 00:41:57,738 --> 00:42:01,155 Organic or traditional breads are exempt. 714 00:42:03,304 --> 00:42:06,037 Folic acid supplements are also recommended for women 715 00:42:06,037 --> 00:42:08,370 planning to become pregnant. 716 00:42:09,427 --> 00:42:14,016 I had no idea about folate before I fell pregnant. 717 00:42:14,016 --> 00:42:17,766 I didn't even know about neural tube defects. 718 00:42:19,200 --> 00:42:23,213 How it would have changed things if I'd have had folate 719 00:42:23,213 --> 00:42:25,380 in the early stages, we... 720 00:42:29,865 --> 00:42:32,485 That would have been a huge difference, maybe Kim wouldn't 721 00:42:32,485 --> 00:42:33,568 be like this. 722 00:42:37,062 --> 00:42:41,645 I can't change what's happened, it happened and I can't 723 00:42:43,524 --> 00:42:45,357 blame myself for that. 724 00:42:46,723 --> 00:42:49,640 (players shouting) 725 00:42:51,434 --> 00:42:53,524 With folic acid fortification 726 00:42:53,524 --> 00:42:56,553 and supplementation, the rate of neural tube defects 727 00:42:56,553 --> 00:42:58,553 in Australia has halved. 728 00:43:01,271 --> 00:43:03,127 I think it's pretty cool to be doing something 729 00:43:03,127 --> 00:43:04,127 that I love. 730 00:43:05,972 --> 00:43:08,467 A lot of people ask me "If you could, would you prefer not 731 00:43:08,467 --> 00:43:11,177 "to be in a wheelchair" and I say no because of maybe I 732 00:43:11,177 --> 00:43:13,876 never would have done all the things that I've done and I'm 733 00:43:13,876 --> 00:43:17,630 fairly satisfied with where I am and where I'm going. 734 00:43:17,630 --> 00:43:20,547 (crowd applauding) 735 00:43:31,474 --> 00:43:34,098 Over 4000 neural tube defects occur every 736 00:43:34,098 --> 00:43:38,419 year in the European union, yet fortification is not 737 00:43:38,419 --> 00:43:39,669 mandatory here. 738 00:43:40,695 --> 00:43:44,445 So why is Europe taking a different approach? 739 00:43:46,604 --> 00:43:48,793 (foreign language) 740 00:43:48,793 --> 00:43:52,055 Dr. Mathilde Touvier leads a team of French researchers 741 00:43:52,055 --> 00:43:54,720 investigating the relationships between nutrition 742 00:43:54,720 --> 00:43:56,281 and health. 743 00:43:56,281 --> 00:43:58,037 I'll take that, thank you. 744 00:43:58,037 --> 00:43:59,589 It's all yours. Thank you. 745 00:43:59,589 --> 00:44:01,713 How much of this bread is fortified? 746 00:44:01,713 --> 00:44:04,522 No bread is fortified, in France, we don't fortify 747 00:44:04,522 --> 00:44:06,522 the flour with anything. 748 00:44:07,642 --> 00:44:09,932 But you have the same problems here with neural tube 749 00:44:09,932 --> 00:44:11,582 defects. 750 00:44:11,582 --> 00:44:15,574 Yes, sure, in fact, it is recommended for women who want 751 00:44:15,574 --> 00:44:18,963 to get pregnant or at the beginning of pregnancy to increase 752 00:44:18,963 --> 00:44:23,300 their intakes of vitamin B9 to prevent these birth defects. 753 00:44:23,300 --> 00:44:25,238 But why not just put it in the bread? 754 00:44:25,238 --> 00:44:29,444 No, the bread in France is quite a secret and traditional 755 00:44:29,444 --> 00:44:32,611 product, and no, it's not transformed. 756 00:44:34,154 --> 00:44:36,694 But do you add vitamins to any foods? 757 00:44:36,694 --> 00:44:39,745 Yes, there are fortifications of food with some vitamins 758 00:44:39,745 --> 00:44:42,160 or minerals but it's not mandatory, it's at the 759 00:44:42,160 --> 00:44:44,323 discretion of manufacturers. 760 00:44:44,323 --> 00:44:45,782 A lot of people around the world are worried about 761 00:44:45,782 --> 00:44:47,763 getting too few vitamins. 762 00:44:47,763 --> 00:44:49,521 Your concern is too many. 763 00:44:49,521 --> 00:44:53,562 Yeah, it depends on country such as France or Europe. 764 00:44:53,562 --> 00:44:57,156 You don't have problems of deficiency in general, you really 765 00:44:57,156 --> 00:45:01,361 have much more problem of excess, excess in the sugar, 766 00:45:01,361 --> 00:45:04,103 salt, and so on and maybe excess in vitamins if you take 767 00:45:04,103 --> 00:45:07,261 fortified foods, stable foods rich in vitamins, minerals 768 00:45:07,261 --> 00:45:09,032 and daily supplements. 769 00:45:09,032 --> 00:45:12,199 Maybe you can reach excessive intakes. 770 00:45:14,068 --> 00:45:16,971 The fortification of food by governments is the result 771 00:45:16,971 --> 00:45:21,122 of a careful assessment of potential risks versus benefits, 772 00:45:21,122 --> 00:45:24,643 but these days, industry can modify almost any food or 773 00:45:24,643 --> 00:45:29,204 drink with additional nutrients without the same scrutiny. 774 00:45:29,204 --> 00:45:32,163 In the United States, you can find a claim about the things 775 00:45:32,163 --> 00:45:35,338 that these products bring to you, 200 percent of which you 776 00:45:35,338 --> 00:45:39,838 need per day, and if the recommendation is 100 person, 777 00:45:41,035 --> 00:45:44,659 why are you taking 200 per person, and American people 778 00:45:44,659 --> 00:45:47,446 are used to such claims and they are used with this idea 779 00:45:47,446 --> 00:45:50,779 of too much of a thing is really better. 780 00:45:52,239 --> 00:45:56,165 In Europe, we really don't have this state of mind. 781 00:45:56,165 --> 00:45:58,564 Today, there is one vitamin in particular that's 782 00:45:58,564 --> 00:46:02,420 increasingly being added to our food, vitamin D. 783 00:46:02,420 --> 00:46:05,679 Low vitamin D has been linked to cancer, heart disease, 784 00:46:05,679 --> 00:46:10,054 dementia, it's been linked to over 100 different conditions. 785 00:46:10,054 --> 00:46:12,475 There are some who claim we're in a midst of a global 786 00:46:12,475 --> 00:46:15,028 vitamin D deficiency. 787 00:46:15,028 --> 00:46:17,392 So how do we decide whether we need extra vitamin D 788 00:46:17,392 --> 00:46:18,225 or not? 789 00:46:20,052 --> 00:46:22,802 (peaceful music) 790 00:46:36,335 --> 00:46:39,886 I've come to one of the coldest places on Earth 791 00:46:39,886 --> 00:46:44,469 to better understand the hottest vitamin on the planet. 792 00:46:49,217 --> 00:46:53,124 For centuries, a mysterious and horrible condition affected 793 00:46:53,124 --> 00:46:55,920 thousands of children all around the world. 794 00:46:55,920 --> 00:46:59,356 Their bones grew weak and broke easily and many were 795 00:46:59,356 --> 00:47:01,023 deformed, many died. 796 00:47:04,181 --> 00:47:07,446 They call the condition rickets, but no one knew 797 00:47:07,446 --> 00:47:08,696 what caused it. 798 00:47:10,336 --> 00:47:13,659 Oddly, here on the Norwegian coast, fewer cases were 799 00:47:13,659 --> 00:47:17,909 reported, so an important clue appeared to be fish. 800 00:47:19,574 --> 00:47:21,991 (airy music) 801 00:47:35,113 --> 00:47:38,062 The world's greatest cod harvest takes place here 802 00:47:38,062 --> 00:47:39,895 from January to April. 803 00:47:41,023 --> 00:47:44,106 (machinery whirring) 804 00:47:47,566 --> 00:47:50,672 Millions of tons are caught, their flesh 805 00:47:50,672 --> 00:47:52,589 helping feed the world. 806 00:47:55,978 --> 00:47:57,728 That is one big fish! 807 00:47:58,805 --> 00:48:01,807 But there's another benefit. 808 00:48:01,807 --> 00:48:06,224 A powerful traditional medicine called cod liver oil. 809 00:48:07,667 --> 00:48:10,398 Here in Norway, the stories of the healing powers of 810 00:48:10,398 --> 00:48:14,731 the cod liver oil go back more than 1000 years. 811 00:48:14,731 --> 00:48:17,975 It was a key part of the viking diet, prized for its 812 00:48:17,975 --> 00:48:20,830 strength giving utilities. 813 00:48:20,830 --> 00:48:24,163 The Norse called it the gold of the sea. 814 00:48:25,470 --> 00:48:28,145 This is a messy business. 815 00:48:28,145 --> 00:48:31,292 I don't know that I like it very much. 816 00:48:31,292 --> 00:48:35,042 So how do you know which one has a big liver? 817 00:48:36,177 --> 00:48:37,594 That's the liver. 818 00:48:39,483 --> 00:48:41,657 So the cod liver oil, do you think of it as a food 819 00:48:41,657 --> 00:48:43,074 or as a medicine? 820 00:48:55,092 --> 00:48:56,425 Not really sick. 821 00:48:57,282 --> 00:48:59,282 Does it taste like fish? 822 00:49:00,246 --> 00:49:02,163 Do you like the flavor? 823 00:49:07,193 --> 00:49:09,507 (laughing) 824 00:49:09,507 --> 00:49:11,924 (airy music) 825 00:49:17,548 --> 00:49:21,033 There are hundreds of thousands of heads and tails strung 826 00:49:21,033 --> 00:49:25,242 out on drying racks almost every village. 827 00:49:25,242 --> 00:49:29,582 And it's incredible to see the scale of the cod fishing here 828 00:49:29,582 --> 00:49:30,749 and the smell. 829 00:49:31,946 --> 00:49:35,869 The stench of cod blankets entire villages. 830 00:49:35,869 --> 00:49:39,810 The locals say it's the smell of money, but the value 831 00:49:39,810 --> 00:49:43,404 of cod and their livers goes far beyond money. 832 00:49:43,404 --> 00:49:45,321 It's also about health. 833 00:49:47,200 --> 00:49:49,783 (gulls crying) 834 00:49:52,767 --> 00:49:55,453 Professor Magritt Brustad is an expert in the links 835 00:49:55,453 --> 00:49:59,536 between food like cod and diseases, like rickets. 836 00:50:01,545 --> 00:50:06,249 Rickets was a huge problem in Norway some years ago. 837 00:50:06,249 --> 00:50:10,999 Rickets is a condition that is characterized by soft bone 838 00:50:13,038 --> 00:50:17,949 so it causes your bone and your skeleton be disformed 839 00:50:17,949 --> 00:50:20,427 and it's rather painful. 840 00:50:20,427 --> 00:50:22,504 And if this happens in childhood, 841 00:50:22,504 --> 00:50:23,819 it's permanent. 842 00:50:23,819 --> 00:50:27,136 Yeah, if it's not treated. 843 00:50:27,136 --> 00:50:30,122 I mean, this is just horrible. 844 00:50:30,122 --> 00:50:31,955 Yeah, a lot of pain. 845 00:50:34,947 --> 00:50:38,831 We knew many years ago that cod liver oil could cure 846 00:50:38,831 --> 00:50:41,498 rickets, but we didn't know why. 847 00:50:42,799 --> 00:50:46,248 Magritt and I have come to see how codfish is turned 848 00:50:46,248 --> 00:50:48,575 into cod liver oil. 849 00:50:48,575 --> 00:50:49,878 Welcome. Thank you! 850 00:50:49,878 --> 00:50:52,628 You are not seeing this before. 851 00:50:53,716 --> 00:50:56,958 It's a simple if revolting business. 852 00:50:56,958 --> 00:51:00,400 Cut out the fish livers, throw them into barrels, 853 00:51:00,400 --> 00:51:03,025 and let them decompose. 854 00:51:03,025 --> 00:51:07,260 The oil grows darker in the rotting process. 855 00:51:07,260 --> 00:51:12,001 Then skim off the oil from the surface and drink. 856 00:51:12,001 --> 00:51:13,834 You sure this is safe? 857 00:51:17,398 --> 00:51:19,981 Yeah, it's not bad. 858 00:51:22,704 --> 00:51:23,780 (all laughing) 859 00:51:23,780 --> 00:51:25,254 That was much better 860 00:51:25,254 --> 00:51:26,754 than I remember it as a child. 861 00:51:26,754 --> 00:51:27,587 Really? 862 00:51:28,653 --> 00:51:32,925 It's not nearly as bad as I was expecting. 863 00:51:32,925 --> 00:51:36,100 Cod liver oil was so successful in treating rickets 864 00:51:36,100 --> 00:51:37,957 that people across Europe began 865 00:51:37,957 --> 00:51:40,374 feeding it to their children. 866 00:51:41,264 --> 00:51:46,181 In the 1870s, it reached America, and mass marketing began. 867 00:51:50,210 --> 00:51:52,877 (vibrant music) 868 00:51:53,809 --> 00:51:57,392 But still, no one understood why it worked. 869 00:52:02,856 --> 00:52:06,441 In the early days, cod liver oil was mostly marketed 870 00:52:06,441 --> 00:52:11,441 as again, a kind of product that would help build flesh. 871 00:52:11,865 --> 00:52:15,520 In fact, this one product here of Scott's Emulsion, one of 872 00:52:15,520 --> 00:52:18,399 the biggest cod liver oil products. 873 00:52:18,399 --> 00:52:22,407 Scott started making this product in the 1870s. 874 00:52:22,407 --> 00:52:26,738 He really believed in advertising and he was able to make 875 00:52:26,738 --> 00:52:30,659 a fortune off of this particular product. 876 00:52:30,659 --> 00:52:32,842 You know, the important thing is if you're marketing this, 877 00:52:32,842 --> 00:52:36,755 you want people to take it as much as possible. 878 00:52:36,755 --> 00:52:39,836 By the late 1890s, the cod liver oil industry 879 00:52:39,836 --> 00:52:43,205 was booming, but the marketing ran decades ahead of 880 00:52:43,205 --> 00:52:44,205 the science. 881 00:52:45,683 --> 00:52:49,896 It wasn't until 1913 that biochemist Elmer McCullum 882 00:52:49,896 --> 00:52:52,752 and Marguerite Davis proved the existence of an essential 883 00:52:52,752 --> 00:52:55,272 nutrient in cod liver oil. 884 00:52:55,272 --> 00:52:58,045 They called it fat soluble A. 885 00:52:58,045 --> 00:53:00,628 A simply for the first vitamin. 886 00:53:01,516 --> 00:53:05,141 McCullum later identified another vitamin in cod liver oil, 887 00:53:05,141 --> 00:53:07,974 fat soluble D, the fourth vitamin. 888 00:53:09,951 --> 00:53:14,618 And McCullum proved it was vitamin D that cured rickets. 889 00:53:15,593 --> 00:53:18,062 So you have this new scientific knowledge coalescing with 890 00:53:18,062 --> 00:53:21,894 what is already kind of a market out there, so if you're 891 00:53:21,894 --> 00:53:24,863 marketing this stuff, I can't imagine anything better 892 00:53:24,863 --> 00:53:26,335 to come along. 893 00:53:26,335 --> 00:53:27,523 - [Derek] It's pretty incredible, right? 894 00:53:27,523 --> 00:53:30,476 It is pretty incredible. 895 00:53:30,476 --> 00:53:35,071 And there were hints of something else at play. 896 00:53:35,071 --> 00:53:38,285 In 1920, microbiologist Harriette Chick carried out an 897 00:53:38,285 --> 00:53:40,368 experiment with children. 898 00:53:41,947 --> 00:53:46,706 Half were given cod liver oil, the other half were not. 899 00:53:46,706 --> 00:53:48,783 As expected, the children given the oil 900 00:53:48,783 --> 00:53:52,844 didn't develop rickets, but then Dr. Chick noticed that 901 00:53:52,844 --> 00:53:56,678 children with rickets who spent time outside in the sun 902 00:53:56,678 --> 00:53:57,928 healed rapidly. 903 00:53:58,879 --> 00:54:02,323 She determined that cod liver oil and sunshine both 904 00:54:02,323 --> 00:54:03,490 cured rickets. 905 00:54:07,063 --> 00:54:09,230 And vitamin D is the link. 906 00:54:16,391 --> 00:54:19,097 How's that sunlight feeling? 907 00:54:19,097 --> 00:54:20,570 Oh, it's wonderful. 908 00:54:20,570 --> 00:54:21,837 Isn't it? 909 00:54:21,837 --> 00:54:25,004 So how does the sun deliver a vitamin? 910 00:54:25,934 --> 00:54:30,192 When sunlight hits our skin, something remarkable happens. 911 00:54:30,192 --> 00:54:34,747 Just under the surface lies a type of cholesterol. 912 00:54:34,747 --> 00:54:37,678 When the sun's ultraviolet rays hit this molecule, 913 00:54:37,678 --> 00:54:41,345 it transforms, becoming a form of vitamin D. 914 00:54:42,974 --> 00:54:47,652 This is the same molecule found in cod liver oil. 915 00:54:47,652 --> 00:54:50,638 It then travels to the liver, where it's converted into 916 00:54:50,638 --> 00:54:54,952 the form that doctors measure in our blood. 917 00:54:54,952 --> 00:54:58,869 This is then activated by the kidneys, and now, 918 00:55:00,621 --> 00:55:05,050 it's ready to help absorb calcium, building strong, healthy, 919 00:55:05,050 --> 00:55:06,633 rickets free bones. 920 00:55:07,827 --> 00:55:10,495 Think that's about enough sun for one day. 921 00:55:10,495 --> 00:55:12,912 (airy music) 922 00:55:19,066 --> 00:55:22,729 But here in the far north, during the dark winter months, 923 00:55:22,729 --> 00:55:25,900 there's a distinct lack of sunshine, so to get enough 924 00:55:25,900 --> 00:55:30,387 vitamin D, over generations, people have devised rather 925 00:55:30,387 --> 00:55:32,970 remarkable meals to compensate. 926 00:55:34,097 --> 00:55:35,264 This is cod. 927 00:55:36,453 --> 00:55:40,748 And this is cod eggs, and this is the boiled liver. 928 00:55:40,748 --> 00:55:43,688 It's fresh cod liver oil together with onion and pepper 929 00:55:43,688 --> 00:55:45,260 and salt. 930 00:55:45,260 --> 00:55:49,141 And this is potatoes, Norwegians always have potato. 931 00:55:49,141 --> 00:55:51,928 Ahh, very good. 932 00:55:51,928 --> 00:55:54,760 This is the traditional (foreign language), 933 00:55:54,760 --> 00:55:57,400 packed with vitamin D. 934 00:55:57,400 --> 00:56:00,343 So one meal of this will give you 16 out of 20 935 00:56:00,343 --> 00:56:05,063 daily doses of the recommended amount of vitamin D. 936 00:56:05,063 --> 00:56:08,175 This has kind of saved our vitamin D health 937 00:56:08,175 --> 00:56:10,525 in the north during the dark season. 938 00:56:10,525 --> 00:56:13,596 But not everyone likes oily fish, let alone 939 00:56:13,596 --> 00:56:16,096 fish livers and cod liver oil. 940 00:56:17,386 --> 00:56:21,523 So scientists invented something far more palatable. 941 00:56:21,523 --> 00:56:25,231 So the first really important vitamin pill is this 942 00:56:25,231 --> 00:56:30,231 Osdogal, and this was developed actually by Casimir Funk. 943 00:56:30,662 --> 00:56:34,333 We've solved a big problem that messy, nauseating oil 944 00:56:34,333 --> 00:56:38,861 is now a nice little pill in (mumbles) coated. 945 00:56:38,861 --> 00:56:41,686 So cod liver oil really started this whole vitamin 946 00:56:41,686 --> 00:56:43,126 explosion? 947 00:56:43,126 --> 00:56:46,822 Yes, cod liver oil really is the beginning of it. 948 00:56:46,822 --> 00:56:49,405 (bright music) 949 00:56:50,299 --> 00:56:52,729 With the new pills readily available, the era 950 00:56:52,729 --> 00:56:57,092 of cod as a key source of vitamin D was ended, and soon, 951 00:56:57,092 --> 00:57:00,092 the vast majority of vitamin D would be created in an 952 00:57:00,092 --> 00:57:05,092 utterly different manner from an utterly different beast. 953 00:57:05,415 --> 00:57:08,165 (sheep bleating) 954 00:57:09,640 --> 00:57:13,053 Today, most of the world's vitamin D pills are created 955 00:57:13,053 --> 00:57:15,553 from the greasy wool of sheep. 956 00:57:16,838 --> 00:57:18,838 Mostly Australian sheep. 957 00:57:20,561 --> 00:57:23,700 (clippers buzzing) 958 00:57:23,700 --> 00:57:27,450 So how do you turn sheep wool into a vitamin? 959 00:57:28,996 --> 00:57:30,663 Let's give it a try. 960 00:57:33,175 --> 00:57:36,924 Well, the wool is coated in a type of grease or lanolin, 961 00:57:36,924 --> 00:57:40,394 it's the stuff that makes your hands feel soft. 962 00:57:40,394 --> 00:57:42,870 It's a mixture of fatty acids produced by the sheep's 963 00:57:42,870 --> 00:57:47,787 oil glands, and this lanolin is the key to making synthetic 964 00:57:48,921 --> 00:57:49,754 vitamin D. 965 00:57:51,347 --> 00:57:54,750 (sheep bleating) 966 00:57:54,750 --> 00:57:56,917 Here's how it can be done. 967 00:58:00,123 --> 00:58:02,981 The lanolin is separated from the wool by boiling in 968 00:58:02,981 --> 00:58:04,981 hot water and detergent. 969 00:58:05,981 --> 00:58:09,993 Around 15 percent of the lanolin is a form of cholesterol, 970 00:58:09,993 --> 00:58:12,993 like the cholesterol under our skin. 971 00:58:14,076 --> 00:58:18,529 This is a extracted and oxidized to produce a new compound 972 00:58:18,529 --> 00:58:21,736 which is then irradiated with ultraviolet light, 973 00:58:21,736 --> 00:58:25,569 transforming it into a precursor of vitamin D. 974 00:58:27,131 --> 00:58:30,425 This chemical process mimics the biological process 975 00:58:30,425 --> 00:58:33,175 of the sunlight hitting our skin. 976 00:58:34,063 --> 00:58:36,898 Several more steps create the end product, 977 00:58:36,898 --> 00:58:38,565 synthetic vitamin D. 978 00:58:43,269 --> 00:58:46,502 And of course, it's not done like this, but on an 979 00:58:46,502 --> 00:58:49,002 industrial scale in factories. 980 00:58:49,963 --> 00:58:52,713 (peaceful music) 981 00:58:55,728 --> 00:58:57,684 Chemists from the University of Melbourne calculated 982 00:58:57,684 --> 00:59:01,486 that you can make a lot of money from a sheep's fleece. 983 00:59:01,486 --> 00:59:04,599 Online, vitamin D3 can seel for about 50 Australian 984 00:59:04,599 --> 00:59:08,893 dollars per gram, but packaged in pill form, it can sell 985 00:59:08,893 --> 00:59:11,643 for around 3700 dollars per gram. 986 00:59:13,523 --> 00:59:17,606 This makes vitamin D far more valuable than gold. 987 00:59:20,024 --> 00:59:23,157 But the million dollar question is should we be taking 988 00:59:23,157 --> 00:59:24,490 vitamin D pills? 989 00:59:36,013 --> 00:59:38,513 (tense music) 990 00:59:41,566 --> 00:59:45,837 Today, most of us spend large parts of our days indoors, 991 00:59:45,837 --> 00:59:49,535 with limited exposure to direct sunlight. 992 00:59:49,535 --> 00:59:52,438 So do we need more vitamin D? 993 00:59:52,438 --> 00:59:55,105 Should we be taking supplements? 994 00:59:56,051 --> 00:59:59,240 Dr. Rachel Neale is part of a global investigation 995 00:59:59,240 --> 01:00:00,823 trying to find out. 996 01:00:02,240 --> 01:00:05,850 Vitamin D's not just a vitamin, vitamin D is a hormone 997 01:00:05,850 --> 01:00:08,320 that has a range of incredibly powerful effects 998 01:00:08,320 --> 01:00:11,590 on the cells in our body that could determine whether or not 999 01:00:11,590 --> 01:00:14,789 that cell starts to divide uncontrollably and become 1000 01:00:14,789 --> 01:00:17,471 a cancer for example or whether or not that cell gets 1001 01:00:17,471 --> 01:00:19,804 a mutation and kills itself. 1002 01:00:20,974 --> 01:00:23,918 So it's this incredibly powerful molecule that we need 1003 01:00:23,918 --> 01:00:27,340 to understand a lot more about before we just recommend 1004 01:00:27,340 --> 01:00:30,673 that everybody should take a supplement. 1005 01:00:33,627 --> 01:00:35,798 Rachel leads one of the world's largest 1006 01:00:35,798 --> 01:00:39,159 clinical trials of high dose vitamin D. 1007 01:00:39,159 --> 01:00:44,159 21 thousand people are taking a vitamin D pill or a placebo, 1008 01:00:44,168 --> 01:00:46,585 a sugar pill, for five years. 1009 01:00:47,543 --> 01:00:50,402 They're trying to see if taking vitamin D supplements 1010 01:00:50,402 --> 01:00:54,235 reduces the risk of cancer and other diseases. 1011 01:00:55,510 --> 01:00:59,183 I think the general public have a perception that 1012 01:00:59,183 --> 01:01:02,894 vitamin D is proven to be beneficial for a whole range 1013 01:01:02,894 --> 01:01:04,956 of different health outcomes, like cancer and 1014 01:01:04,956 --> 01:01:07,407 cardiovascular disease and the reality is that we know 1015 01:01:07,407 --> 01:01:10,831 vitamin D's incredibly important for our bones, but beyond 1016 01:01:10,831 --> 01:01:13,331 that, we don't yet have proof. 1017 01:01:14,176 --> 01:01:16,740 So why all the uncertainty? 1018 01:01:16,740 --> 01:01:21,153 Well first, there's debate around how much we actually need. 1019 01:01:21,153 --> 01:01:24,638 Vitamin D is measured in our blood in units generally 1020 01:01:24,638 --> 01:01:26,888 called nanomoles per liter. 1021 01:01:27,878 --> 01:01:32,309 Experts agree that below 25 is considered deficient, 1022 01:01:32,309 --> 01:01:35,251 but knowing what levels are sufficient is trickier. 1023 01:01:35,251 --> 01:01:37,232 A level over 50 is generally thought to be enough 1024 01:01:37,232 --> 01:01:41,649 for good bone health for most people but others argue 1025 01:01:44,271 --> 01:01:46,688 for 75 or 100 or even higher. 1026 01:01:49,097 --> 01:01:52,557 It's worth noting that the US used a different measure, 1027 01:01:52,557 --> 01:01:56,646 nanograms per milliliter and like metric versus imperial, 1028 01:01:56,646 --> 01:01:59,896 this can cause international confusion. 1029 01:02:01,199 --> 01:02:05,426 So we don't yet have a single number that is accepted 1030 01:02:05,426 --> 01:02:09,056 by all organizations and all scientists and all doctors 1031 01:02:09,056 --> 01:02:10,473 around the world. 1032 01:02:11,737 --> 01:02:16,319 There's also controversy around blood testing, 1033 01:02:16,319 --> 01:02:17,846 with studies showing different labs can get very different 1034 01:02:17,846 --> 01:02:21,887 results, and although we know taking supplements increases 1035 01:02:21,887 --> 01:02:25,759 the levels of vitamin D in our blood, we don't yet know 1036 01:02:25,759 --> 01:02:28,419 if this improves our health. 1037 01:02:28,419 --> 01:02:31,002 (lively music) 1038 01:02:44,054 --> 01:02:47,096 So we don't know what vitamin D does yet. 1039 01:02:47,096 --> 01:02:50,054 We've got hints about what vitamin D might do but what 1040 01:02:50,054 --> 01:02:51,955 we don't know is- 1041 01:02:51,955 --> 01:02:53,901 Different kinds of studies are revealing 1042 01:02:53,901 --> 01:02:56,616 different kinds of clues. 1043 01:02:56,616 --> 01:02:58,993 These people are getting a fair amount of vitamin D. 1044 01:02:58,993 --> 01:03:00,388 They are. 1045 01:03:00,388 --> 01:03:02,463 Vitamin D studies are often 1046 01:03:02,463 --> 01:03:06,790 observational, meaning they observe the world as it is. 1047 01:03:06,790 --> 01:03:09,707 For example, people with cancer often have low levels 1048 01:03:09,707 --> 01:03:11,810 of vitamin D in their blood. 1049 01:03:11,810 --> 01:03:15,681 The link is clear and potentially important. 1050 01:03:15,681 --> 01:03:19,255 But it doesn't tell us if low vitamin D caused the cancer 1051 01:03:19,255 --> 01:03:22,422 or if the cancer caused low vitamin D. 1052 01:03:25,489 --> 01:03:28,885 To work it out, we need to do the kind of study pioneered 1053 01:03:28,885 --> 01:03:31,135 by James Lind back in 1747. 1054 01:03:32,412 --> 01:03:34,829 The randomized control trial. 1055 01:03:35,857 --> 01:03:40,535 Take a group of people, divide randomly in two, give 1056 01:03:40,535 --> 01:03:45,134 vitamin D to one group and a placebo to the other, then, if 1057 01:03:45,134 --> 01:03:47,874 you see a difference between these groups, you know it was 1058 01:03:47,874 --> 01:03:52,541 caused by vitamin D, and better still, do this at scale. 1059 01:03:53,896 --> 01:03:56,334 The more people in your study, the more confident you can 1060 01:03:56,334 --> 01:03:57,834 be of the results. 1061 01:03:59,495 --> 01:04:02,245 Rachel's results are due in 2021. 1062 01:04:06,657 --> 01:04:09,528 It's very exciting but currently the jury really is out 1063 01:04:09,528 --> 01:04:13,861 on what we should be recommending to the population. 1064 01:04:19,920 --> 01:04:23,022 Despite the uncertainty, in 2016, UK 1065 01:04:23,022 --> 01:04:25,896 scientists recommended an increase in the recommended 1066 01:04:25,896 --> 01:04:28,063 daily amount of vitamin D. 1067 01:04:29,736 --> 01:04:31,403 Not everyone agrees. 1068 01:04:32,945 --> 01:04:35,893 One high profile champion of vitamin D has since changed 1069 01:04:35,893 --> 01:04:36,726 his mind. 1070 01:04:37,878 --> 01:04:40,628 Geneticist professor Tim Spector. 1071 01:04:41,646 --> 01:04:44,865 I've studied vitamin D a lot in the last 15 years 1072 01:04:44,865 --> 01:04:46,755 and we were the first group to show 1073 01:04:46,755 --> 01:04:49,572 that the levels in individuals is 1074 01:04:49,572 --> 01:04:53,383 actually partly controlled by your genes so we always assume 1075 01:04:53,383 --> 01:04:56,864 it's purely how much sunshine you get or how much oily fish 1076 01:04:56,864 --> 01:05:00,917 you're eating but in fact, about 50 percent of the levels 1077 01:05:00,917 --> 01:05:04,398 vary just because the genes you've got and so everyone 1078 01:05:04,398 --> 01:05:08,697 has a different normal level of their vitamins and that is 1079 01:05:08,697 --> 01:05:11,144 generally holding true for all the vitamins we've been able 1080 01:05:11,144 --> 01:05:15,038 to test so far so our idea of normal should actually be very 1081 01:05:15,038 --> 01:05:18,554 person specific so you might have a normal level that's 1082 01:05:18,554 --> 01:05:21,988 three times higher than mine and we don't really know what 1083 01:05:21,988 --> 01:05:24,738 is the good level and what's low. 1084 01:05:25,737 --> 01:05:28,071 I think the public (mumbles) realize there is a controversy 1085 01:05:28,071 --> 01:05:31,742 here and all these amounts of vitamins are important for us, 1086 01:05:31,742 --> 01:05:33,819 but let's wait for the proper trials before we make a 1087 01:05:33,819 --> 01:05:36,993 decision rather than the default being the artificial 1088 01:05:36,993 --> 01:05:40,325 chemical first, worry about it later. 1089 01:05:40,325 --> 01:05:42,097 Let's get our facts right, make sure we're not doing 1090 01:05:42,097 --> 01:05:44,232 something harmful first. 1091 01:05:44,232 --> 01:05:46,118 There's no doubt that we need to clinically manage 1092 01:05:46,118 --> 01:05:49,285 people who have vitamin deficiency, it's important we 1093 01:05:49,285 --> 01:05:53,109 recognize that vitamin D deficiency is a real thing, but we 1094 01:05:53,109 --> 01:05:56,640 don't yet have the evidence to be able to say to the general 1095 01:05:56,640 --> 01:06:01,640 population taking a vitamin D supplement is a good thing. 1096 01:06:02,042 --> 01:06:05,359 So should we just get more sun? 1097 01:06:05,359 --> 01:06:08,149 What about the risk of skin cancer? 1098 01:06:08,149 --> 01:06:13,149 Well, like everything around vitamin D, it's complicated. 1099 01:06:13,291 --> 01:06:15,896 In sunny climates, most people get enough from short bursts 1100 01:06:15,896 --> 01:06:19,201 of sunshine a few times a week. 1101 01:06:19,201 --> 01:06:22,824 Although of course sunscreen should always be used. 1102 01:06:22,824 --> 01:06:26,756 And in less sunny places, more deliberate sun exposure 1103 01:06:26,756 --> 01:06:31,756 may be needed, or your doctor may recommend supplementation. 1104 01:06:33,469 --> 01:06:38,469 Vitamin D is powerful, no question, but can we get too much 1105 01:06:38,520 --> 01:06:40,436 of a good thing? 1106 01:06:40,436 --> 01:06:42,936 (tense music) 1107 01:06:53,740 --> 01:06:58,367 They were born at 9:45, so he came out first and she was 1108 01:06:58,367 --> 01:07:02,187 a minute later, so they're just a minute apart. 1109 01:07:02,187 --> 01:07:04,634 When Becky Jackson gave birth to twins Joe 1110 01:07:04,634 --> 01:07:07,358 and Elizabeth, she was thrilled. 1111 01:07:07,358 --> 01:07:09,591 So that's three months and you know, 1112 01:07:09,591 --> 01:07:12,069 Joe was such a little chunkalunk at first. 1113 01:07:12,069 --> 01:07:13,890 But when she noticed her five month old 1114 01:07:13,890 --> 01:07:17,397 daughter wasn't growing as quickly as her twin brother, 1115 01:07:17,397 --> 01:07:19,412 Becky began to worry. 1116 01:07:19,412 --> 01:07:22,194 And so here's five months and you can see her eyes look 1117 01:07:22,194 --> 01:07:26,349 a little baggy and sunken and her face just looks 1118 01:07:26,349 --> 01:07:28,097 a little strange. 1119 01:07:28,097 --> 01:07:32,142 These pictures, nothing was alarming really until this one. 1120 01:07:32,142 --> 01:07:35,074 Suddenly, things took a turn for the worse. 1121 01:07:35,074 --> 01:07:38,848 Elizabeth wasn't gaining weight and she just wouldn't eat. 1122 01:07:38,848 --> 01:07:41,694 I noticed one day when I was changing her diaper that 1123 01:07:41,694 --> 01:07:44,179 her stomach looked sunken, I could see the bottom of her 1124 01:07:44,179 --> 01:07:48,929 ribcage and her skin looked and felt strange, almost like 1125 01:07:49,781 --> 01:07:51,436 pizza dough. 1126 01:07:51,436 --> 01:07:54,480 Becky took her to the doctor for blood tests. 1127 01:07:54,480 --> 01:07:56,858 The next day, the doctor called. 1128 01:07:56,858 --> 01:08:00,803 She said "You have to go to children's hospital right now, 1129 01:08:00,803 --> 01:08:05,094 "everything is all over the place, things that are low 1130 01:08:05,094 --> 01:08:07,568 "should be high, things that are high should be low, 1131 01:08:07,568 --> 01:08:10,644 "nothing is where it should be." 1132 01:08:10,644 --> 01:08:13,144 (tense music) 1133 01:08:18,478 --> 01:08:23,203 I was freaking out, I was panicked, I didn't know what any 1134 01:08:23,203 --> 01:08:28,036 of it meant for a couple of days which was the scary part. 1135 01:08:28,961 --> 01:08:31,667 The tests revealed that Elizabeth had toxic 1136 01:08:31,667 --> 01:08:35,509 levels of vitamin D and this was causing dangerously high 1137 01:08:35,509 --> 01:08:38,092 levels of calcium in her blood. 1138 01:08:39,493 --> 01:08:43,586 I have never seen a case of vitamin D toxicity until 1139 01:08:43,586 --> 01:08:44,919 I saw Elizabeth. 1140 01:08:45,986 --> 01:08:49,554 She's only five or six months old and pretty much a baby's 1141 01:08:49,554 --> 01:08:52,759 diet is mostly formula, so we had to do a little 1142 01:08:52,759 --> 01:08:57,759 investigation why or where could she have gotten that. 1143 01:08:57,816 --> 01:09:01,378 When they first said the words "hypercalcemia" to me, 1144 01:09:01,378 --> 01:09:05,013 then I did what every parent does and I googled and I got 1145 01:09:05,013 --> 01:09:08,980 online and I found out everything I could about it and then 1146 01:09:08,980 --> 01:09:11,907 I started to see a recurring theme of high doses of 1147 01:09:11,907 --> 01:09:14,852 vitamin D, vitamin D overdose. 1148 01:09:14,852 --> 01:09:16,602 And I knew instantly. 1149 01:09:19,082 --> 01:09:21,978 So you start with powdered goat's milk and you put in 1150 01:09:21,978 --> 01:09:23,749 eight scoops. 1151 01:09:23,749 --> 01:09:25,444 Becky didn't have enough breast milk for 1152 01:09:25,444 --> 01:09:28,463 both twins, so she decided to keep Joe on breast milk 1153 01:09:28,463 --> 01:09:31,610 while Elizabeth received a mix of breast milk and homemade 1154 01:09:31,610 --> 01:09:33,261 formula. 1155 01:09:33,261 --> 01:09:36,428 Vitamin C, vitamin E, coral calcium. 1156 01:09:39,490 --> 01:09:41,729 This is cod liver oil. 1157 01:09:41,729 --> 01:09:44,248 It was an organic recipe of goat milk 1158 01:09:44,248 --> 01:09:47,364 and coconut milk from a local health store. 1159 01:09:47,364 --> 01:09:51,427 And this was the soy lecithin which is a thickener. 1160 01:09:51,427 --> 01:09:53,834 And wanting to do the best for her baby, 1161 01:09:53,834 --> 01:09:57,401 Becky decided to add a little something extra to the mix. 1162 01:09:57,401 --> 01:10:00,053 And then lastly is the vitamin D. 1163 01:10:00,053 --> 01:10:01,795 How much do you put in? 1164 01:10:01,795 --> 01:10:04,962 Well, the recipe calls for one drop. 1165 01:10:07,149 --> 01:10:08,463 One drop. 1166 01:10:08,463 --> 01:10:09,296 That's all that-- that's it. 1167 01:10:09,296 --> 01:10:12,053 Put in. Which seems trivial 1168 01:10:12,053 --> 01:10:15,401 at best, that's just silliness, that's not gonna do anything 1169 01:10:15,401 --> 01:10:19,401 for anybody, so I would do the whole dropperful. 1170 01:10:22,483 --> 01:10:26,111 One ML or full dropper, like most infant droppers, 1171 01:10:26,111 --> 01:10:29,028 would contain about 20 to 30 drops. 1172 01:10:31,658 --> 01:10:34,603 If there's too much vitamin D, then you will reabsorb 1173 01:10:34,603 --> 01:10:39,210 a lot of the calcium, then it causes some of the symptoms 1174 01:10:39,210 --> 01:10:43,022 would be increased urination, lack of appetite, both of 1175 01:10:43,022 --> 01:10:45,889 which could lead to dehydration. 1176 01:10:45,889 --> 01:10:49,396 If this condition persisted without any treatment 1177 01:10:49,396 --> 01:10:53,353 or intervention, this could ultimately lead to Elizabeth 1178 01:10:53,353 --> 01:10:55,186 having kidney failure. 1179 01:11:00,783 --> 01:11:03,463 And then this was in the actual hospital with the feeding 1180 01:11:03,463 --> 01:11:07,177 tube but she's rounded out, she's plumped up and had 1181 01:11:07,177 --> 01:11:10,231 started to look normal again. 1182 01:11:10,231 --> 01:11:12,540 It took 10 days in hospital to stabilize 1183 01:11:12,540 --> 01:11:13,457 her levels. 1184 01:11:14,719 --> 01:11:16,469 I felt very guilty. 1185 01:11:17,335 --> 01:11:21,982 I did this, this is something that I did and I knew that I 1186 01:11:21,982 --> 01:11:25,885 was giving her too much when I was doing it but I thought 1187 01:11:25,885 --> 01:11:27,270 "What harm could there be? 1188 01:11:27,270 --> 01:11:29,634 "It's just a vitamin, it's like vitamin C, you get rid 1189 01:11:29,634 --> 01:11:34,051 "of what you don't need, how could it be a big deal?" 1190 01:11:35,199 --> 01:11:38,085 I was trying to be a good mom, I was trying to go above 1191 01:11:38,085 --> 01:11:42,418 and beyond in a very easy, every day way that seemed 1192 01:11:43,612 --> 01:11:44,612 so harmless. 1193 01:11:49,633 --> 01:11:53,094 I think people have underestimated the power of these 1194 01:11:53,094 --> 01:11:55,094 vitamins with vitamin D. 1195 01:11:57,814 --> 01:12:02,632 You know, little mistakes can mean a lot if it's tenfold, 1196 01:12:02,632 --> 01:12:06,299 hundredfold, that can really spell disaster. 1197 01:12:08,574 --> 01:12:11,080 Luckily, Elizabeth is now fine. 1198 01:12:11,080 --> 01:12:12,913 Her levels are normal. 1199 01:12:14,892 --> 01:12:18,329 It's difficult to overdose on vitamins in food, but easy 1200 01:12:18,329 --> 01:12:21,747 to do with manmade vitamins as they can be consumed in such 1201 01:12:21,747 --> 01:12:26,090 large quantities, and fat soluble vitamins like D can 1202 01:12:26,090 --> 01:12:30,257 accumulate in body fat, reaching dangerous levels. 1203 01:12:36,396 --> 01:12:39,056 Becky Jackson and her family are not alone. 1204 01:12:39,056 --> 01:12:42,860 In 2015, the US Poison Center reported over 3000 calls 1205 01:12:42,860 --> 01:12:45,384 concerning children under six who had taken too much 1206 01:12:45,384 --> 01:12:46,217 vitamin D. 1207 01:12:48,692 --> 01:12:51,192 (tense music) 1208 01:12:56,153 --> 01:12:58,716 Throughout the world, the potential risks of dietary 1209 01:12:58,716 --> 01:13:02,439 supplements are being studied carefully. 1210 01:13:02,439 --> 01:13:05,655 There's no question now that we have the data after 1211 01:13:05,655 --> 01:13:09,818 decades of study, really, that the supplements are not 1212 01:13:09,818 --> 01:13:11,206 risk free. 1213 01:13:11,206 --> 01:13:13,440 And in America, supplements send tens of thousands of 1214 01:13:13,440 --> 01:13:17,722 consumers to emergency departments every year and thousands 1215 01:13:17,722 --> 01:13:20,942 of hospitalizations every year are due to serious side 1216 01:13:20,942 --> 01:13:23,445 effects of supplements. 1217 01:13:23,445 --> 01:13:25,224 Tonight, Walgreens and Target have pulled 1218 01:13:25,224 --> 01:13:27,009 the products nationwide. 1219 01:13:27,009 --> 01:13:28,465 GNC did the same in-- 1220 01:13:28,465 --> 01:13:31,378 In 2015, dietary supplements were pulled off 1221 01:13:31,378 --> 01:13:35,775 the shelves of four major pharmacy chains in New York. 1222 01:13:35,775 --> 01:13:38,174 Most of the supplements tested didn't contain the 1223 01:13:38,174 --> 01:13:41,687 materials listed on the label and many contained 1224 01:13:41,687 --> 01:13:42,770 contaminants. 1225 01:13:44,497 --> 01:13:47,364 One of the serious safety concerns has been serious 1226 01:13:47,364 --> 01:13:50,558 deficits in the manufacturing process. 1227 01:13:50,558 --> 01:13:53,095 For example, there have been multi-vitamins in which the 1228 01:13:53,095 --> 01:13:57,457 amount of a mineral has been 100 times greater than what 1229 01:13:57,457 --> 01:14:01,448 it should be, leading to serious health defects. 1230 01:14:01,448 --> 01:14:04,615 In other multi-vitamins, there has been drugs that weren't 1231 01:14:04,615 --> 01:14:08,281 supposed to be in there at all, such as anabolic steroids, 1232 01:14:08,281 --> 01:14:10,722 these are steroids that weightlifters might clandestinely 1233 01:14:10,722 --> 01:14:14,522 use to get stronger have been found in multi-vitamins 1234 01:14:14,522 --> 01:14:19,420 at such levels that people taking it became sick. 1235 01:14:19,420 --> 01:14:22,139 Specific risks are appearing around specific 1236 01:14:22,139 --> 01:14:24,222 vitamins, like vitamin D. 1237 01:14:25,094 --> 01:14:28,542 We're seeing levels of five times, ten times normal 1238 01:14:28,542 --> 01:14:31,562 in the blood of my patients when I see them with 1239 01:14:31,562 --> 01:14:35,622 osteopetrosis and studies are now showing these people 1240 01:14:35,622 --> 01:14:38,644 are now actually more prone to fractures and more prone 1241 01:14:38,644 --> 01:14:43,226 to falling down and all the evidence is building up that we 1242 01:14:43,226 --> 01:14:47,890 actually have a fairly narrow range of where these 1243 01:14:47,890 --> 01:14:49,057 vitamins work. 1244 01:14:50,632 --> 01:14:53,369 Every vitamin has a toxic level and some of them are 1245 01:14:53,369 --> 01:14:55,591 actually not that much higher than just the normal 1246 01:14:55,591 --> 01:14:57,546 nutritional amount. 1247 01:14:57,546 --> 01:15:01,280 I see patients all the time who have vitamin B six levels 1248 01:15:01,280 --> 01:15:03,890 in the toxic range and it can cause nerve damage 1249 01:15:03,890 --> 01:15:04,890 for example. 1250 01:15:06,646 --> 01:15:09,373 In the 1990s, studies testing a form of 1251 01:15:09,373 --> 01:15:13,344 vitamin A were halted when it became clear that participants 1252 01:15:13,344 --> 01:15:16,261 were at an increased risk of dying. 1253 01:15:17,913 --> 01:15:21,552 That really shocked I think almost everyone. 1254 01:15:21,552 --> 01:15:23,807 We need to look at the type of supplement, we need to look 1255 01:15:23,807 --> 01:15:26,314 at the amount of supplement, we need to look at what's 1256 01:15:26,314 --> 01:15:30,049 being given to and it does seem that there are some places 1257 01:15:30,049 --> 01:15:33,565 where vitamin supplements can definitely provide benefit, 1258 01:15:33,565 --> 01:15:36,120 there are a number of places where they can provide 1259 01:15:36,120 --> 01:15:39,089 some harm and there are a lot of places where they're still 1260 01:15:39,089 --> 01:15:42,183 not sure what the outcomes will be. 1261 01:15:42,183 --> 01:15:46,255 So the big picture is that these products are not 1262 01:15:46,255 --> 01:15:47,997 entirely safe. 1263 01:15:47,997 --> 01:15:49,909 It's not that they're gonna harm everyone who's gonna take 1264 01:15:49,909 --> 01:15:51,436 them, certainly not. 1265 01:15:51,436 --> 01:15:52,997 The majority of people aren't gonna experience any 1266 01:15:52,997 --> 01:15:54,731 adverse effects. 1267 01:15:54,731 --> 01:15:56,730 But my concern is this. 1268 01:15:56,730 --> 01:16:01,730 If these products are offering none to almost no benefit 1269 01:16:02,154 --> 01:16:07,154 to a healthy consumer, but posing a small risk of harm, 1270 01:16:07,259 --> 01:16:10,482 why should we be recommending them and why should consumers 1271 01:16:10,482 --> 01:16:11,649 be using them? 1272 01:16:14,633 --> 01:16:16,342 Now there's no questions that medicines can have 1273 01:16:16,342 --> 01:16:18,547 dangerous side effects and complications. 1274 01:16:18,547 --> 01:16:20,874 But they're clearly stated on the label and doctors know 1275 01:16:20,874 --> 01:16:22,161 to look out for them. 1276 01:16:22,161 --> 01:16:23,601 It's a known risk. 1277 01:16:23,601 --> 01:16:26,123 The issue with vitamins and dietary supplements is that 1278 01:16:26,123 --> 01:16:28,789 they're perceived to be risk free. 1279 01:16:28,789 --> 01:16:31,619 Yet there can be complications, there can be side effects, 1280 01:16:31,619 --> 01:16:34,063 and there can be bad products. 1281 01:16:34,063 --> 01:16:36,220 It's not a no risk proposition. 1282 01:16:36,220 --> 01:16:38,803 (lively music) 1283 01:16:41,428 --> 01:16:44,778 Yet, in the US, there's no legal requirement for products 1284 01:16:44,778 --> 01:16:47,645 to be tested for safety or effectiveness before 1285 01:16:47,645 --> 01:16:48,978 they go on sale. 1286 01:16:50,411 --> 01:16:53,220 In the US and in many countries, the laws are lax to the 1287 01:16:53,220 --> 01:16:55,120 point where you can basically put any combination of 1288 01:16:55,120 --> 01:16:58,486 vitamins and minerals in a pill, call it anything you want 1289 01:16:58,486 --> 01:17:01,545 and make pseudo-health claims for it. 1290 01:17:01,545 --> 01:17:03,378 So it's the wild west. 1291 01:17:05,509 --> 01:17:08,930 Clearly, there is a huge problem in supplement use that's 1292 01:17:08,930 --> 01:17:11,422 not regulated, there are things there 1293 01:17:11,422 --> 01:17:12,694 that shouldn't be there, 1294 01:17:12,694 --> 01:17:16,161 there are things that should be there that aren't there. 1295 01:17:16,161 --> 01:17:19,218 It is sort of the wild west. 1296 01:17:19,218 --> 01:17:21,925 To understand how this could happen, we need 1297 01:17:21,925 --> 01:17:23,008 to look back. 1298 01:17:26,651 --> 01:17:29,156 To see how the line between food 1299 01:17:29,156 --> 01:17:31,489 and medicine became blurred. 1300 01:17:33,283 --> 01:17:38,283 ♪ Well, let's talk about the US government of 1938 ♪ 1301 01:17:40,132 --> 01:17:45,132 ♪ The burgeoning new industry, they didn't regulate ♪ 1302 01:17:46,668 --> 01:17:48,108 ♪ Said it makes no sense ♪ 1303 01:17:48,108 --> 01:17:53,108 ♪ They're just dispensing nutrients my dear ♪ 1304 01:17:53,592 --> 01:17:58,592 ♪ And if we pop that bottle top, we know what we would hear ♪ 1305 01:17:58,773 --> 01:18:03,773 ♪ I am not a medicine, I am not a drug ♪ 1306 01:18:04,848 --> 01:18:08,811 ♪ Dude, I'm food, so don't intrude, it's rude ♪ 1307 01:18:08,811 --> 01:18:12,256 ♪ To pull my plug ♪ 1308 01:18:12,256 --> 01:18:17,256 ♪ I wanna be a mystery, don't peer inside the pill ♪ 1309 01:18:19,253 --> 01:18:23,089 ♪ And if I'm not a medicine ♪ 1310 01:18:23,089 --> 01:18:26,506 ♪ Perhaps you never will ♪ 1311 01:18:28,561 --> 01:18:31,736 In 1938, a new US law requires all pharmaceutical 1312 01:18:31,736 --> 01:18:35,184 drugs to be tested for safety, but vitamins escaped 1313 01:18:35,184 --> 01:18:37,605 this regulation, opening the door for the industry 1314 01:18:37,605 --> 01:18:38,981 to expand. 1315 01:18:38,981 --> 01:18:41,824 And by the 1970s, the industry is booming. 1316 01:18:41,824 --> 01:18:44,716 The FDA, concerned about high dose vitamins, tries to 1317 01:18:44,716 --> 01:18:47,543 tighten the rules, but fails. 1318 01:18:47,543 --> 01:18:49,412 They try again in the 90s. 1319 01:18:49,412 --> 01:18:51,502 This time, they want better labeling and to remove 1320 01:18:51,502 --> 01:18:53,276 unsafe products. 1321 01:18:53,276 --> 01:18:55,517 But the industry fights back, claiming the regulation 1322 01:18:55,517 --> 01:19:00,282 will make it too expensive and limit consumer choice. 1323 01:19:00,282 --> 01:19:05,282 ♪ You know I wear my therapeutic promises with pride ♪ 1324 01:19:06,915 --> 01:19:11,915 ♪ But every name I have to claim discreetly qualified ♪ 1325 01:19:13,466 --> 01:19:18,466 ♪ No reason to investigate, no reason to delay ♪ 1326 01:19:20,359 --> 01:19:24,781 ♪ You might just live forever if you take me twice a day ♪ 1327 01:19:24,781 --> 01:19:29,781 ♪ Oh but I am not a medicine, I am not a drug ♪ 1328 01:19:32,108 --> 01:19:37,108 ♪ To keep me cheap you need to sweep me right under the rug ♪ 1329 01:19:38,774 --> 01:19:43,774 ♪ Hey FDA, get out the way, why can't we stay like this ♪ 1330 01:19:45,437 --> 01:19:50,437 ♪ Where I am not a medicine ♪ 1331 01:19:52,245 --> 01:19:55,662 ♪ And ignorance is bliss ♪ 1332 01:19:59,717 --> 01:20:04,717 In 1994, a new US law is passed, forbidding the testing 1333 01:20:04,957 --> 01:20:07,927 of dietary supplements for safety or effectiveness 1334 01:20:07,927 --> 01:20:08,927 before sale. 1335 01:20:15,356 --> 01:20:18,794 And the industry explodes from around 4000 products 1336 01:20:18,794 --> 01:20:19,961 to over 85000. 1337 01:20:22,499 --> 01:20:24,249 Perhaps the most surprising part about the way that 1338 01:20:24,249 --> 01:20:27,612 supplements are regulated is that it is because of 1339 01:20:27,612 --> 01:20:31,307 us consumers, we supported this legislation. 1340 01:20:31,307 --> 01:20:35,035 We lobbied on behalf of the dietary supplement industry 1341 01:20:35,035 --> 01:20:38,931 to get congress to pass a sweeping law in 1994 that 1342 01:20:38,931 --> 01:20:42,608 forever forbade the FDA from requiring that dietary 1343 01:20:42,608 --> 01:20:46,398 supplements be tested or for efficacy before they're sold. 1344 01:20:46,398 --> 01:20:48,015 What do you mean forever? 1345 01:20:48,015 --> 01:20:52,268 Like unless there's another law, that's just how it is. 1346 01:20:52,268 --> 01:20:54,685 (soft music) 1347 01:20:56,407 --> 01:21:00,406 Different countries have different regulations. 1348 01:21:00,406 --> 01:21:02,972 In Australia, most vitamin products are classified as 1349 01:21:02,972 --> 01:21:04,972 complimentary medicines. 1350 01:21:06,118 --> 01:21:08,844 Manufacturers must certify that they use low risk 1351 01:21:08,844 --> 01:21:11,458 ingredients, products contain what they say they 1352 01:21:11,458 --> 01:21:16,458 contain and they have evidence to back up health claims. 1353 01:21:16,856 --> 01:21:20,037 But, it's a trust based system. 1354 01:21:20,037 --> 01:21:23,355 Products don't have to be proven safe or effective 1355 01:21:23,355 --> 01:21:25,272 before they go on sale. 1356 01:21:29,117 --> 01:21:31,687 In Europe, vitamin products are regulated as food 1357 01:21:31,687 --> 01:21:35,207 supplements and again, they don't have to be tested 1358 01:21:35,207 --> 01:21:37,557 before they go on sale. 1359 01:21:37,557 --> 01:21:39,466 However, the laws are tougher. 1360 01:21:39,466 --> 01:21:42,207 To claim a health benefit, for example, manufacturers 1361 01:21:42,207 --> 01:21:47,110 must show proven scientific evidence, and in France, 1362 01:21:47,110 --> 01:21:49,991 high doses of vitamins generally need a medical 1363 01:21:49,991 --> 01:21:51,074 prescription. 1364 01:21:54,700 --> 01:21:56,655 But increasingly, people are buying their vitamin 1365 01:21:56,655 --> 01:21:58,447 products online. 1366 01:21:58,447 --> 01:22:00,947 (tense music) 1367 01:22:05,779 --> 01:22:09,196 So globally, it's a case of buyer beware. 1368 01:22:10,430 --> 01:22:13,462 (players shouting) 1369 01:22:13,462 --> 01:22:18,126 And yet, we can't forget that in cases of real deficiency, 1370 01:22:18,126 --> 01:22:21,459 vitamin supplements can transform lives. 1371 01:22:25,941 --> 01:22:28,441 They can save a child's sight. 1372 01:22:30,279 --> 01:22:32,279 They can be life savers. 1373 01:22:34,078 --> 01:22:38,262 But what if we're healthy, with no known deficiency? 1374 01:22:38,262 --> 01:22:42,012 How do we decide whether to take them or not? 1375 01:22:44,210 --> 01:22:47,693 My final stop is to meet experts planning the ultimate 1376 01:22:47,693 --> 01:22:48,860 human journey. 1377 01:22:51,956 --> 01:22:56,123 I wanna know, are they taking supplements to Mars? 1378 01:22:59,291 --> 01:23:00,923 And liftoff. 1379 01:23:00,923 --> 01:23:05,137 The (mumbles) of (mumbles) hit a new era of American 1380 01:23:05,137 --> 01:23:06,637 space exploration. 1381 01:23:12,356 --> 01:23:15,090 NASA is preparing to send humans to Mars 1382 01:23:15,090 --> 01:23:16,090 around 2030. 1383 01:23:19,378 --> 01:23:22,775 Imagine a three year round trip with only the food 1384 01:23:22,775 --> 01:23:25,192 you have on board to survive. 1385 01:23:26,555 --> 01:23:28,500 They can't go down the street and go to a restaurant. 1386 01:23:28,500 --> 01:23:30,773 If they don't like what you've provided, they can't go 1387 01:23:30,773 --> 01:23:34,342 to the grocery store and have hundreds of choices. 1388 01:23:34,342 --> 01:23:37,546 So this is where we freeze dry the products. 1389 01:23:37,546 --> 01:23:40,190 Dr. Grace Douglas leads NASA's research into 1390 01:23:40,190 --> 01:23:43,302 the nutritional needs of astronauts. 1391 01:23:43,302 --> 01:23:46,757 The focus is on taking whole foods into space. 1392 01:23:46,757 --> 01:23:49,588 And all of our freeze dried foods get made in this lab 1393 01:23:49,588 --> 01:23:51,950 here, so cook like you would at home and then they get put 1394 01:23:51,950 --> 01:23:56,950 in here frozen and the moisture gets pulled out of them. 1395 01:23:57,082 --> 01:24:00,025 In flight, they'll add the water back and it rehydrates 1396 01:24:00,025 --> 01:24:02,753 to be just like the meal it was before we pulled 1397 01:24:02,753 --> 01:24:04,152 the water out. 1398 01:24:04,152 --> 01:24:06,198 Some of the vitamins actually do really well through 1399 01:24:06,198 --> 01:24:07,670 this process. 1400 01:24:07,670 --> 01:24:10,753 (cheerful whistling) 1401 01:24:14,556 --> 01:24:18,999 Strawberry shortcake, ready for you, Chris. 1402 01:24:18,999 --> 01:24:20,325 I like the look of this, 1403 01:24:20,325 --> 01:24:22,242 this is your shrimp dish, is it? 1404 01:24:22,242 --> 01:24:24,518 That's shrimp cocktail. Wow, these are really 1405 01:24:24,518 --> 01:24:26,705 cool, and a burger, of course, very American. 1406 01:24:26,705 --> 01:24:28,178 Yes. 1407 01:24:28,178 --> 01:24:31,967 So this one's sweet and sour chicken. 1408 01:24:31,967 --> 01:24:36,926 Honey coming out pretty well there, there we go. 1409 01:24:36,926 --> 01:24:38,894 Chocolate pudding cake. 1410 01:24:38,894 --> 01:24:41,100 So will NASA be sending vitamin supplements 1411 01:24:41,100 --> 01:24:42,646 to Mars? 1412 01:24:42,646 --> 01:24:43,948 Pretty good. 1413 01:24:43,948 --> 01:24:45,950 The only one we send is vitamin D and that's because 1414 01:24:45,950 --> 01:24:47,836 you get a lot of your vitamin D exposure from sunlight 1415 01:24:47,836 --> 01:24:50,736 exposure on your skin and we're not gonna have that option 1416 01:24:50,736 --> 01:24:52,207 in space flight. 1417 01:24:52,207 --> 01:24:53,409 Only vitamin D? 1418 01:24:53,409 --> 01:24:56,025 Yeah, we expect that we have all the other nutrients 1419 01:24:56,025 --> 01:24:59,674 in a wide variety of a balanced food system. 1420 01:24:59,674 --> 01:25:01,836 Why is food better than supplements? 1421 01:25:01,836 --> 01:25:06,086 Food is just core and fundamental to every aspect 1422 01:25:06,953 --> 01:25:09,272 of human health and performance, so it's central 1423 01:25:09,272 --> 01:25:12,300 to these missions and there's really no way because there's 1424 01:25:12,300 --> 01:25:14,714 so many different vitamins in food, there's so many 1425 01:25:14,714 --> 01:25:17,895 things that you're getting that you can't replicate 1426 01:25:17,895 --> 01:25:19,895 at this point in a pill. 1427 01:25:20,799 --> 01:25:24,248 Okay, there we go, it says 75, so we're gonna put in 75. 1428 01:25:24,248 --> 01:25:26,936 I mean to me, it feels like the linchpin, right? 1429 01:25:26,936 --> 01:25:30,411 To determine whether a crew gets to Mars and is happy and 1430 01:25:30,411 --> 01:25:33,094 healthy and ready to go. 1431 01:25:33,094 --> 01:25:35,084 It sounds to me comes down to the food. 1432 01:25:35,084 --> 01:25:36,517 It's one of the great needs, 1433 01:25:36,517 --> 01:25:37,733 you have oxygen, water, and food, 1434 01:25:37,733 --> 01:25:39,504 and no matter what, you can't go anywhere 1435 01:25:39,504 --> 01:25:41,378 or do anything with the human system without those three 1436 01:25:41,378 --> 01:25:43,497 critical things. 1437 01:25:43,497 --> 01:25:44,330 How do you like it? 1438 01:25:44,330 --> 01:25:48,247 It's fantastic, I would eat this, absolutely. 1439 01:25:49,398 --> 01:25:50,904 For three years. 1440 01:25:50,904 --> 01:25:52,895 For three years, this is all I get? 1441 01:25:52,895 --> 01:25:53,728 Yeah. 1442 01:25:56,195 --> 01:25:57,952 This is mission control Houston. 1443 01:25:57,952 --> 01:26:00,272 As we come up on the first two critical Orion program 1444 01:26:00,272 --> 01:26:03,978 milestones, the service module faring panel jettison 1445 01:26:03,978 --> 01:26:05,962 and the launch abort system jettison-- 1446 01:26:05,962 --> 01:26:08,277 Our growing understanding of the power 1447 01:26:08,277 --> 01:26:12,027 of food is revealing something extraordinary. 1448 01:26:16,843 --> 01:26:19,979 As well as the 13 vitamins, there are thousands of other 1449 01:26:19,979 --> 01:26:24,573 chemicals in food, a multitude of molecules working 1450 01:26:24,573 --> 01:26:27,906 in complex and often mysterious synergy. 1451 01:26:30,671 --> 01:26:34,370 Together, they protect against disease, but they don't 1452 01:26:34,370 --> 01:26:37,805 always have that same power if they're isolated 1453 01:26:37,805 --> 01:26:38,972 from our food. 1454 01:26:40,988 --> 01:26:43,571 (all laughing) 1455 01:26:46,838 --> 01:26:50,869 At this point in time, we can't begin to think that a 1456 01:26:50,869 --> 01:26:54,577 supplement could replicate what we would get from a food 1457 01:26:54,577 --> 01:26:57,494 or replace whole foods in our diet. 1458 01:26:58,448 --> 01:27:02,604 Foods contain dozens of essential micronutrients, but they 1459 01:27:02,604 --> 01:27:05,997 also contain literally thousands of compounds that we've 1460 01:27:05,997 --> 01:27:10,215 only minimally studied up until this point in time. 1461 01:27:10,215 --> 01:27:12,844 Even if it's comfortable to think that this pill will 1462 01:27:12,844 --> 01:27:16,924 solve many problem of the daily life and will prevent 1463 01:27:16,924 --> 01:27:20,512 longterm or chronic diseases, and it's not true and it's not 1464 01:27:20,512 --> 01:27:23,711 proven for the moment and what is proven are the 1465 01:27:23,711 --> 01:27:26,794 relationship between diet and health. 1466 01:27:29,092 --> 01:27:31,144 I actually think it's unfortunate that there's been 1467 01:27:31,144 --> 01:27:34,863 so much hype and pseudoscience around vitamins, so you 1468 01:27:34,863 --> 01:27:39,190 have people who are evidence based, science based who think 1469 01:27:39,190 --> 01:27:42,137 "Oh, vitamins are all nonsense," no, they're not, actually, 1470 01:27:42,137 --> 01:27:45,804 it's science, it's nutrition, it's medicine. 1471 01:27:46,848 --> 01:27:51,088 What's nonsense is over hyping vitamins or pretending that 1472 01:27:51,088 --> 01:27:54,005 they're something that they're not. 1473 01:27:57,405 --> 01:27:59,595 You know, before, when I thought of vitamins, I thought 1474 01:27:59,595 --> 01:28:00,974 of pills. 1475 01:28:00,974 --> 01:28:04,003 I had kind of forgotten that they all come from food, but 1476 01:28:04,003 --> 01:28:06,049 now I've learned it's really not that hard to get everything 1477 01:28:06,049 --> 01:28:09,408 you need from food and there's so much more to food than 1478 01:28:09,408 --> 01:28:11,420 we currently understand. 1479 01:28:11,420 --> 01:28:13,782 After all, we've been getting our food from vitamins for 1480 01:28:13,782 --> 01:28:15,728 millions of years. 1481 01:28:15,728 --> 01:28:18,469 You think we'd have it all worked out in barely a hundred? 1482 01:28:18,469 --> 01:28:20,124 So should we take our vitamins? 1483 01:28:20,124 --> 01:28:21,166 Yes! 1484 01:28:21,166 --> 01:28:23,877 By eating good food, and if you feel like you need something 1485 01:28:23,877 --> 01:28:26,855 extra, maybe the best thing to do is think of vitamins 1486 01:28:26,855 --> 01:28:28,317 as if they're medicines. 1487 01:28:28,317 --> 01:28:32,234 That is, if you take them, take them seriously. 1488 01:28:34,017 --> 01:28:38,434 (people chattering under soft music) 1489 01:28:52,338 --> 01:28:54,838 (tense music) 1489 01:28:55,305 --> 01:29:01,639 Support us and become VIP member to remove all ads from www.OpenSubtitles.org 121488

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