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1
00:00:05,316 --> 00:00:06,250
Whoo!
2
00:00:06,283 --> 00:00:08,219
All right, hold on.
I got to turn up here.
3
00:00:10,821 --> 00:00:12,723
Whoo! Hoo-hoo-hoo-hoo!
4
00:00:18,329 --> 00:00:19,696
How cool was that?
5
00:00:19,730 --> 00:00:23,334
That was way cool.
Oh.
6
00:00:23,367 --> 00:00:25,802
[both panting]
7
00:00:25,836 --> 00:00:27,371
My turn.
8
00:00:27,404 --> 00:00:28,839
No, sorry,
that's not allowed.
9
00:00:28,872 --> 00:00:30,441
I just signed 15 pages
of forms,
10
00:00:30,474 --> 00:00:32,376
saying you gotta ride on
the back of that thing.
11
00:00:32,409 --> 00:00:33,810
I don't see
any lawyers around.
12
00:00:33,844 --> 00:00:34,811
You know that's
not the point.
13
00:00:34,845 --> 00:00:38,182
No, you just wanna keep
all the fun to yourself.
14
00:00:40,184 --> 00:00:41,485
Come on, Dad.
15
00:00:41,518 --> 00:00:44,255
You go over 15,
we're pulling over.
16
00:00:44,288 --> 00:00:45,489
All right, I mean it.
You're the best.
17
00:00:45,522 --> 00:00:49,793
All right, get on there.
Put on your goggles.
18
00:00:49,826 --> 00:00:51,895
Ready?
19
00:00:51,928 --> 00:00:53,297
Got the clutch in?
20
00:00:53,330 --> 00:00:55,666
All right, that's my boy.
Whoo!
21
00:00:55,699 --> 00:00:59,170
Hoo-hoo!
22
00:00:59,203 --> 00:01:00,471
Whoo!
23
00:01:02,173 --> 00:01:03,707
Whoo!
24
00:01:08,179 --> 00:01:09,846
Adam, you're going too fast.
Slow it down.
25
00:01:13,884 --> 00:01:15,819
I mean it.
You're going too fast.
26
00:01:15,852 --> 00:01:17,554
Slow down!
27
00:01:17,588 --> 00:01:18,755
Adam!
28
00:01:23,360 --> 00:01:25,128
Adam!
29
00:01:26,563 --> 00:01:28,432
Let go of the throttle!
30
00:01:33,470 --> 00:01:36,207
No! Adam! No!
31
00:01:39,210 --> 00:01:42,179
[Massive Attack's Teardrop]
32
00:01:42,213 --> 00:01:50,221
*
33
00:02:11,708 --> 00:02:12,809
What do you got?
34
00:02:12,843 --> 00:02:15,279
16-year-old, status post,
ATV crash,
35
00:02:15,312 --> 00:02:16,647
40% of burns on his body.
36
00:02:16,680 --> 00:02:18,249
Nasotracheal intubation.
37
00:02:18,282 --> 00:02:19,783
Start a bag of lactated
Ringer's, wide open.
38
00:02:19,816 --> 00:02:20,817
Is he gonna be okay?
39
00:02:20,851 --> 00:02:22,386
We'll be with you
when we can.
40
00:02:22,419 --> 00:02:23,220
Get him out.
41
00:02:23,254 --> 00:02:25,522
Wait, wait, wait.
42
00:02:25,556 --> 00:02:26,823
I'll start fluids.
43
00:02:26,857 --> 00:02:28,325
Let's go get him moved up.
44
00:02:37,701 --> 00:02:39,370
[scoffs]
45
00:02:43,607 --> 00:02:45,976
[pronouncing Hindi]
De-re-maki.
46
00:02:46,009 --> 00:02:47,778
De-re-maki.
47
00:02:50,414 --> 00:02:52,949
Been looking for you.
Been avoiding you.
48
00:02:52,983 --> 00:02:54,885
Burn unit can handle it.
49
00:02:54,918 --> 00:02:56,320
If they could handle it,
50
00:02:56,353 --> 00:03:00,457
they wouldn't
be asking for you.
51
00:03:00,491 --> 00:03:01,658
Is that a journal?
52
00:03:01,692 --> 00:03:02,726
A friend wrote an article.
53
00:03:02,759 --> 00:03:03,860
In Hindi?
54
00:03:03,894 --> 00:03:06,530
They have a cutting edge
neuroscience program in India.
55
00:03:06,563 --> 00:03:08,632
Says so right on the cover.
56
00:03:11,802 --> 00:03:15,272
This kid's heart rate's messed.
57
00:03:15,306 --> 00:03:18,041
Tachycardia can be
explained by the burn.
58
00:03:18,074 --> 00:03:19,943
I assume the burn
unit knew that.
59
00:03:22,779 --> 00:03:24,715
His potassium's low.
60
00:03:24,748 --> 00:03:26,783
Which can also be
explained by the burn.
61
00:03:26,817 --> 00:03:29,386
Except I'm sure the burn unit's
pumping him with fluids,
62
00:03:29,420 --> 00:03:31,588
which means his potassium
should be going up, not down.
63
00:03:31,622 --> 00:03:33,390
Could be amphetamines.
64
00:03:33,424 --> 00:03:35,426
Or bacteria lunching
on his heart.
65
00:03:35,459 --> 00:03:38,662
Or cardiomyopathy,
or some other very bad thing.
66
00:03:38,695 --> 00:03:41,332
(House)
He needs an EKG.
67
00:03:41,365 --> 00:03:43,334
Eww.
68
00:03:46,337 --> 00:03:50,574
Okay, no skin, no EKG.
69
00:03:50,607 --> 00:03:52,843
(Chase)
Is he even going
to survive the burn?
70
00:03:52,876 --> 00:03:55,446
You got a date or something?
71
00:03:55,479 --> 00:03:58,349
(House)
40% of his body.
72
00:03:58,382 --> 00:04:00,617
If the burns unit can
prevent an infection,
73
00:04:00,651 --> 00:04:02,819
his body will regenerate
maybe 10%.
74
00:04:02,853 --> 00:04:04,355
Surgeon's will do
20 or so grafts.
75
00:04:04,388 --> 00:04:06,089
Six months in this room,
he'll end up with a series
76
00:04:06,122 --> 00:04:07,558
of nasty scars.
77
00:04:07,591 --> 00:04:11,328
(House)
Maybe some pain,
but he'll live.
78
00:04:11,362 --> 00:04:13,630
Unless his heart shuts down,
because we can't figure out
79
00:04:13,664 --> 00:04:17,834
what's causing the low potassium
and tachycardia.
80
00:04:17,868 --> 00:04:21,071
We need help from a Belgian Doc,
named Einthoven.
81
00:04:21,104 --> 00:04:23,440
He's dead.
82
00:04:23,474 --> 00:04:25,041
While he was alive,
he invented a little ditty
83
00:04:25,075 --> 00:04:26,410
called the Galvanometer.
84
00:04:26,443 --> 00:04:28,011
Where do we get one?
85
00:04:28,044 --> 00:04:29,346
Go to any electronics store
86
00:04:29,380 --> 00:04:31,382
that's been open
since before 1905.
87
00:04:31,415 --> 00:04:33,116
There's a good chance
they got one in the corner
88
00:04:33,149 --> 00:04:36,853
in the basement.
89
00:04:36,887 --> 00:04:38,855
(Brenda)
We need an audio/visual
setup for the lecture hall.
90
00:04:38,889 --> 00:04:40,056
What for?
91
00:04:40,090 --> 00:04:41,492
For the lecture.
92
00:04:41,525 --> 00:04:42,726
What lecture?
93
00:04:42,759 --> 00:04:44,395
Dr. Weber's lecture.
94
00:04:44,428 --> 00:04:46,363
Who's Dr. Weber?
95
00:04:46,397 --> 00:04:48,098
Uh, neurologist, I think.
96
00:04:48,131 --> 00:04:49,332
The memo was from you.
97
00:04:56,540 --> 00:04:57,841
Where's my assistant?
98
00:04:57,874 --> 00:04:58,909
She left.
99
00:04:58,942 --> 00:05:00,076
When?
Wednesday.
100
00:05:00,110 --> 00:05:01,144
Seriously?
101
00:05:01,177 --> 00:05:03,414
The temp agency sent someone,
but she got lost.
102
00:05:03,447 --> 00:05:08,084
Well, when she gets here,
fire her.
103
00:05:26,670 --> 00:05:28,805
Oh, yeah.
104
00:05:28,839 --> 00:05:30,407
Did you issue this memo?
105
00:05:30,441 --> 00:05:32,909
Look at that.
106
00:05:32,943 --> 00:05:34,478
Congratulations.
107
00:05:34,511 --> 00:05:36,079
The patient that
has been in a coma
108
00:05:36,112 --> 00:05:37,481
for two years and counting
109
00:05:37,514 --> 00:05:38,782
is still in a coma.
110
00:05:38,815 --> 00:05:40,116
This is not my signature.
111
00:05:40,150 --> 00:05:41,885
I don't know anything
about this guy.
112
00:05:41,918 --> 00:05:43,119
I'm supposed to introduce him?
113
00:05:43,153 --> 00:05:46,490
Have lunch?
114
00:05:46,523 --> 00:05:48,425
The coma patient
has a migraine?
115
00:05:48,459 --> 00:05:49,426
Oh, no, no, no.
116
00:05:49,460 --> 00:05:51,628
No, I gave him medication
to prevent a migraine.
117
00:05:51,662 --> 00:05:52,963
That's a migraine.
118
00:05:52,996 --> 00:05:55,799
(Cuddy)
Increased flow velocity
in his cerebral arteries.
119
00:05:55,832 --> 00:05:57,801
I did, subsequently,
give him nitroglycerin,
120
00:05:57,834 --> 00:05:58,902
which could possibly--
121
00:05:58,935 --> 00:06:02,773
You induced a migraine headache
in a coma patient?
122
00:06:02,806 --> 00:06:04,040
I gave him a little headache.
123
00:06:04,074 --> 00:06:06,477
Similar to the one
you're giving me now.
124
00:06:06,510 --> 00:06:09,480
Have you even read
an ethical guideline?
125
00:06:09,513 --> 00:06:10,847
Well, it'd be wrong to try out
126
00:06:10,881 --> 00:06:12,449
a new migraine
prevention medication
127
00:06:12,483 --> 00:06:13,817
on someone who can
actually feel pain.
128
00:06:13,850 --> 00:06:15,819
Did you sign this?
129
00:06:15,852 --> 00:06:18,154
Uh...yeah.
130
00:06:18,188 --> 00:06:22,493
We can talk later about
the appropriate discipline.
131
00:06:22,526 --> 00:06:24,728
[Cuddy scoffs]
132
00:06:24,761 --> 00:06:26,930
(Cameron)
Because of the burn,
133
00:06:26,963 --> 00:06:28,198
we can't perform any of our
normal tests
134
00:06:28,231 --> 00:06:29,566
to see what's wrong.
135
00:06:29,600 --> 00:06:32,969
So we're going to try
a Galvanometer.
136
00:06:33,003 --> 00:06:35,539
It picks up a pulse
in the wrists and the ankles.
137
00:06:35,572 --> 00:06:38,775
Hopefully it will tell us why
his heart rhythm is abnormal.
138
00:06:38,809 --> 00:06:41,244
What have I done to him.
I--
139
00:06:41,277 --> 00:06:42,546
It was an accident.
140
00:06:42,579 --> 00:06:45,716
All right, so...
141
00:06:45,749 --> 00:06:47,518
he's got all these burns.
142
00:06:47,551 --> 00:06:49,119
And now there's something
wrong with his heart?
143
00:06:49,152 --> 00:06:52,055
We're trying to figure out if
the two are somehow connected.
144
00:06:52,088 --> 00:06:53,757
Had he been sick lately?
145
00:06:53,790 --> 00:06:55,726
No, nothing.
146
00:06:55,759 --> 00:06:57,127
Anything unusual
with his behavior?
147
00:06:57,160 --> 00:06:58,562
Had he been tired a lot?
148
00:06:58,595 --> 00:06:59,863
Nothing.
He was great.
149
00:06:59,896 --> 00:07:01,164
He was happy.
150
00:07:01,197 --> 00:07:04,034
He was just having a great time
and then--
151
00:07:04,067 --> 00:07:05,902
If he was experimenting
with amphetamines
152
00:07:05,936 --> 00:07:08,271
or cocaine--
No.
153
00:07:08,304 --> 00:07:11,207
We gave him some pot
about a year ago to try.
154
00:07:11,241 --> 00:07:12,943
It was just once.
155
00:07:12,976 --> 00:07:14,244
We thought if we took
the mystery
156
00:07:14,277 --> 00:07:16,747
out of drugs and alcohol,
the less he'd experiment.
157
00:07:16,780 --> 00:07:19,550
We'll know more
after the tests.
158
00:07:21,585 --> 00:07:24,888
It looks like they're
gonna electrocute him.
159
00:07:24,921 --> 00:07:27,223
Plug it in.
160
00:07:27,257 --> 00:07:29,593
You plug it in.
161
00:07:29,626 --> 00:07:31,762
Fine. Gimme the cord.
162
00:07:39,770 --> 00:07:43,039
Works.
163
00:07:43,073 --> 00:07:44,575
Prominent U-waves.
164
00:07:44,608 --> 00:07:46,109
No inverted T-wave.
165
00:07:46,142 --> 00:07:47,544
(Chase)
No ischemia.
166
00:07:47,578 --> 00:07:50,113
(Foreman)
Q-wave normal.
167
00:07:50,146 --> 00:07:51,948
That's not good.
168
00:07:56,119 --> 00:07:57,287
Turn it off.
169
00:07:57,320 --> 00:07:58,755
Turn it off!
170
00:07:58,789 --> 00:08:00,791
What's happening?
What is that?
171
00:08:00,824 --> 00:08:02,525
(Chase)
He's seizing, get in here.
172
00:08:09,766 --> 00:08:11,868
(House)
Who electrocuted my patient?
173
00:08:11,902 --> 00:08:13,003
He had a seizure.
174
00:08:13,036 --> 00:08:14,037
(Cameron)
He wasn't electrocuted.
175
00:08:14,070 --> 00:08:16,973
What does the seizure tell us?
Move.
176
00:08:17,007 --> 00:08:18,609
What are you looking for?
177
00:08:18,642 --> 00:08:20,811
Same as you.
Love, acceptance.
178
00:08:20,844 --> 00:08:21,978
Solid return on investments.
179
00:08:22,012 --> 00:08:24,047
Differential diagnosis.
Go.
180
00:08:24,080 --> 00:08:25,849
Could be epilepsy,
or seizure disorder.
181
00:08:25,882 --> 00:08:27,618
Not with the tachycardia.
182
00:08:27,651 --> 00:08:29,152
It could be a virus
in his brain.
183
00:08:29,185 --> 00:08:31,955
Specificity's impressive.
184
00:08:31,988 --> 00:08:34,024
(Chase)
Adrenoleukodystrophy.
185
00:08:34,057 --> 00:08:35,859
Could be M.S.,
seizures could be caused
186
00:08:35,892 --> 00:08:37,193
by plaques and lesions
on the brain.
187
00:08:37,227 --> 00:08:38,829
Well, let's find out which.
188
00:08:38,862 --> 00:08:39,963
Get him an MRI.
189
00:08:39,996 --> 00:08:43,734
No nuclear imaging.
190
00:08:43,767 --> 00:08:45,736
He wouldn't survive the move
to Radiology.
191
00:08:45,769 --> 00:08:47,237
MRI and CT scan are both out.
192
00:08:47,270 --> 00:08:49,205
[scoffs]
Okay.
193
00:08:49,239 --> 00:08:51,107
Lumbar puncture'll tell us
if his proteins are elevated.
194
00:08:51,141 --> 00:08:52,776
At least we can exclude M.S.
195
00:08:52,809 --> 00:08:54,210
Can't do a lumbar
puncture either.
196
00:08:56,412 --> 00:08:58,649
You're cramping my exits.
197
00:08:58,682 --> 00:09:00,651
Don't tell me,
no skin on his spine.
198
00:09:00,684 --> 00:09:02,118
We'd be inserting a needle
into an area
199
00:09:02,152 --> 00:09:03,720
that's teeming with bacteria.
200
00:09:03,754 --> 00:09:05,121
If he doesn't have
a brain infection already,
201
00:09:05,155 --> 00:09:06,890
we'd give him one for sure.
202
00:09:06,923 --> 00:09:09,993
There's no other way
to look at a brain.
203
00:09:10,026 --> 00:09:12,362
Transcranial
Doppler Sonography.
204
00:09:12,395 --> 00:09:14,030
She said brain,
205
00:09:14,064 --> 00:09:15,331
not pregnant woman's uterus.
206
00:09:15,365 --> 00:09:16,667
They do sound alike.
207
00:09:16,700 --> 00:09:18,301
I used one to look
at a brain this morning.
208
00:09:18,334 --> 00:09:20,671
Why didn't you take the patient
to Radiology, get an MRA?
209
00:09:20,704 --> 00:09:23,206
Obviously, I was doing
something illegal,
210
00:09:23,239 --> 00:09:25,742
and using nuclear imaging
would've raised questions.
211
00:09:25,776 --> 00:09:27,177
You're not gonna get
a diagnosis of M.S.
212
00:09:27,210 --> 00:09:28,278
from a sonogram.
213
00:09:28,311 --> 00:09:30,647
Not definitively,
but patients with M.S.
214
00:09:30,681 --> 00:09:34,350
have more reactive neurons
in their occipital cortex.
215
00:09:36,319 --> 00:09:38,288
Okay, then?
216
00:09:41,992 --> 00:09:45,195
Thank you for all coming
to today's lecture
217
00:09:45,228 --> 00:09:47,130
by Dr. Phillip Weber,
218
00:09:47,163 --> 00:09:50,166
who is our guest today
at our hospital
219
00:09:50,200 --> 00:09:54,337
to talk about headaches.
220
00:09:54,370 --> 00:09:57,273
Dr. Weber is
at the Weber Center for Pain.
221
00:09:57,307 --> 00:09:59,042
That makes sense.
222
00:09:59,075 --> 00:10:01,878
Weber-Weber.
So please welcome, Dr. Weber.
223
00:10:08,985 --> 00:10:12,322
Thank you, Doctor...Cuddy.
224
00:10:12,355 --> 00:10:14,257
[audience chuckles]
225
00:10:14,290 --> 00:10:19,262
(Weber)
I suppose I should tell you
a little bit more about myself.
226
00:10:19,295 --> 00:10:21,998
I went to school in Virginia,
and in my undergrad...
227
00:10:22,032 --> 00:10:23,967
You've never to one of these
things in your life.
228
00:10:24,000 --> 00:10:25,001
Who is this guy?
229
00:10:25,035 --> 00:10:28,171
No idea.
230
00:10:28,204 --> 00:10:29,973
What's with the outfit?
231
00:10:30,006 --> 00:10:33,476
Sudden chills,
and light sensitivity.
232
00:10:33,509 --> 00:10:34,677
Inexplicable.
233
00:10:34,711 --> 00:10:39,916
I received my medical degree
at Johns Hopkins University,
234
00:10:39,950 --> 00:10:42,886
where I studied under
Brightman and Gilmar.
235
00:10:42,919 --> 00:10:45,221
Hmm...he must be good.
236
00:10:45,255 --> 00:10:47,958
You went to Hopkins and studied
under Brightman and Gilmar.
237
00:10:47,991 --> 00:10:49,726
Shh...
238
00:10:49,760 --> 00:10:52,863
...helped me win the Doyle
internship at the Mayo clinic.
239
00:10:52,896 --> 00:10:57,734
You were supposed to get
the Doyle internship.
240
00:10:57,768 --> 00:11:00,904
This guy's Von Lieberman?
241
00:11:00,937 --> 00:11:02,438
The guy got you thrown out
for cheating?
242
00:11:02,472 --> 00:11:04,207
The Dean threw me out.
243
00:11:04,240 --> 00:11:06,309
Von Lieberman just ratted on me.
244
00:11:06,342 --> 00:11:07,911
This guy's name is Weber,
not Von Lieberman.
245
00:11:07,944 --> 00:11:13,049
I call Weber Von Lieberman.
Way eviler. Shh...
246
00:11:13,083 --> 00:11:15,251
...and five HT Sub 1D receptors
247
00:11:15,285 --> 00:11:19,155
have improved the acute
treatment of migraines.
248
00:11:19,189 --> 00:11:20,156
To this point...
249
00:11:20,190 --> 00:11:21,925
So what's the plan?
250
00:11:21,958 --> 00:11:25,028
You wanna wait 'til he bends
over and make a fart sound?
251
00:11:25,061 --> 00:11:28,464
I'm not here about the past.
252
00:11:28,498 --> 00:11:31,234
He's a bad scientist.
253
00:11:31,267 --> 00:11:34,037
Well, you cheated off him,
how bad can he be?
254
00:11:34,070 --> 00:11:37,073
He got the answer wrong.
255
00:11:37,107 --> 00:11:40,110
[Weber continues speech]
256
00:11:46,016 --> 00:11:47,417
(Doug)
Are they trying to wake him up?
257
00:11:47,450 --> 00:11:49,385
They can't do that, right?
He'll be in too much pain.
258
00:11:49,419 --> 00:11:51,554
Don't worry, he's still under.
259
00:11:51,587 --> 00:11:54,290
But the brain never completely
sleeps, it's always working.
260
00:11:54,324 --> 00:11:57,293
Controlling your heart rate.
Breathing.
261
00:11:57,327 --> 00:11:59,930
Temperature.
262
00:11:59,963 --> 00:12:01,798
The eyes respond
to visual stimuli.
263
00:12:01,832 --> 00:12:04,000
Blood flow increases
in certain areas of the brain
264
00:12:04,034 --> 00:12:05,969
and we can track that
with a sonogram.
265
00:12:06,002 --> 00:12:09,205
With M.S., blood vessels
are more reactive,
266
00:12:09,239 --> 00:12:10,907
so flow is faster.
267
00:12:10,941 --> 00:12:13,043
If Adam has an infection,
268
00:12:13,076 --> 00:12:15,912
there'd be swelling which would
constrict the arteries,
269
00:12:15,946 --> 00:12:17,914
and the flow would be slower.
270
00:12:17,948 --> 00:12:21,084
Chase,
near the subarachnoid space.
271
00:12:27,858 --> 00:12:29,592
Data from control subjects
were analyzed
272
00:12:29,625 --> 00:12:32,295
with a two-way ANOVA
with status and side
273
00:12:32,328 --> 00:12:34,497
as within-subject factors.
274
00:12:35,932 --> 00:12:38,101
You stalked this guy
for 20 years
275
00:12:38,134 --> 00:12:40,003
just for the shot
to humiliate him?
276
00:12:40,036 --> 00:12:42,038
Shh. I'm trying to learn.
277
00:12:42,072 --> 00:12:43,940
...vessels without
significant rebound.
278
00:12:43,974 --> 00:12:47,010
He doesn't even know
what that means.
279
00:12:47,043 --> 00:12:48,444
You're going
to interrupt him, aren't you?
280
00:12:48,478 --> 00:12:49,980
If I have a question.
281
00:12:50,013 --> 00:12:51,347
And what's that
going to accomplish?
282
00:12:51,381 --> 00:12:54,417
Why can't you just enjoy this?
283
00:12:54,450 --> 00:12:55,952
Why can't you just be
happy for me?
284
00:12:55,986 --> 00:12:58,554
You have got to find
less debilitating outlets
285
00:12:58,588 --> 00:12:59,923
than humiliating people.
286
00:12:59,956 --> 00:13:03,093
I hear bowling is more fun
than stalking.
287
00:13:03,126 --> 00:13:06,329
But I'm better at this.
288
00:13:06,362 --> 00:13:09,900
If P is less than point zero...
289
00:13:09,933 --> 00:13:11,935
Blow a ton of money
on a plasma TV.
290
00:13:11,968 --> 00:13:15,471
We found a subarachnoid
bleed.
291
00:13:15,505 --> 00:13:17,908
Bleed in the head isn't
causing seizures.
292
00:13:17,941 --> 00:13:19,542
It could be.
293
00:13:19,575 --> 00:13:21,978
10% with damage to the cerebral
cortex have seizures.
294
00:13:22,012 --> 00:13:23,613
Or bacterial meningitis.
295
00:13:23,646 --> 00:13:24,647
Viral encephalitis?
296
00:13:24,680 --> 00:13:25,882
There's no way to tell
without--
297
00:13:25,916 --> 00:13:26,883
Shut up!
298
00:13:26,917 --> 00:13:29,920
Excuse me?
299
00:13:29,953 --> 00:13:32,322
Not you.
300
00:13:32,355 --> 00:13:35,225
If my lecture is interrupting
your meeting, I can wait.
301
00:13:35,258 --> 00:13:37,193
[speaks Hindi]
302
00:13:39,395 --> 00:13:41,631
As your people say in India.
Appreciate it.
303
00:13:41,664 --> 00:13:43,533
We'll figure out why later.
304
00:13:43,566 --> 00:13:45,936
Um, fix the bleed, or he dies.
305
00:13:45,969 --> 00:13:48,071
Talk to you
in a couple of hours.
306
00:13:50,006 --> 00:13:52,943
[speaks Hindi]
307
00:14:02,085 --> 00:14:03,553
I'm in the subarachnoid space.
308
00:14:04,955 --> 00:14:06,489
Can you get it?
309
00:14:06,522 --> 00:14:09,059
I think so.
310
00:14:09,092 --> 00:14:11,694
Put the probe back where it was
so I can see the wire.
311
00:14:11,727 --> 00:14:13,029
We're looking for the bleed--
312
00:14:13,063 --> 00:14:15,065
Look when I get there!
313
00:14:15,098 --> 00:14:18,268
I'm flying blind
without a contrast CT here.
314
00:14:27,443 --> 00:14:31,081
And with a p value of less
than .001,
315
00:14:31,114 --> 00:14:33,249
we have strong
statistical evidence
316
00:14:33,283 --> 00:14:35,952
that this drug prevents
migraine headaches
317
00:14:35,986 --> 00:14:38,321
without daily administration.
318
00:14:38,354 --> 00:14:40,290
Uh, excuse me, Doctor.
319
00:14:40,323 --> 00:14:42,258
[whispers]
He knows this field
better than you do.
320
00:14:42,292 --> 00:14:43,659
It's always been
my understanding
321
00:14:43,693 --> 00:14:46,362
that unless you follow
a daily regimen,
322
00:14:46,396 --> 00:14:48,264
no drug can prevent
a migraine.
323
00:14:48,298 --> 00:14:49,966
That's why they call it
a breakthrough.
324
00:14:50,000 --> 00:14:52,135
That's why you call it
a breakthrough.
325
00:14:52,168 --> 00:14:54,704
No, the, uh, pharmaceutical
company sponsoring
326
00:14:54,737 --> 00:14:59,042
my clinical trials also hails it
as a breakthrough.
327
00:14:59,075 --> 00:15:01,044
I'm sure your wife
and lawyer do too.
328
00:15:01,077 --> 00:15:04,380
Is there anybody who doesn't
stand to make a fortune from it,
329
00:15:04,414 --> 00:15:05,581
calling it a breakthrough?
330
00:15:05,615 --> 00:15:06,582
Who are you?
331
00:15:06,616 --> 00:15:10,020
Just a lunatic who
desperately needs a hobby.
332
00:15:10,053 --> 00:15:12,088
How exactly do these
studies work?
333
00:15:12,122 --> 00:15:14,057
Do you give this drug
to a bunch of people
334
00:15:14,090 --> 00:15:15,125
and they don't get a migraine,
you go,
335
00:15:15,158 --> 00:15:17,160
voila, my drug works?
336
00:15:17,193 --> 00:15:19,095
Uh, excuse me, Miss?
337
00:15:19,129 --> 00:15:22,198
(House)
Uh, do you have cancer?
338
00:15:22,232 --> 00:15:25,635
Wow. Mango juice
prevents cancer.
339
00:15:25,668 --> 00:15:29,505
Perhaps I should've taken my
medication before this lecture.
340
00:15:29,539 --> 00:15:32,142
[boisterous laugh]
341
00:15:32,175 --> 00:15:34,210
We had a very specific
control group.
342
00:15:34,244 --> 00:15:36,212
Chronic migraine sufferers.
343
00:15:36,246 --> 00:15:38,481
I don't have time to go through
all the math right now,
344
00:15:38,514 --> 00:15:40,716
but the incidence was
dramatically--
345
00:15:40,750 --> 00:15:41,784
Sure, in India.
346
00:15:41,817 --> 00:15:44,787
Two plus two equals
five there, right?
347
00:15:44,820 --> 00:15:47,057
Do I know you?
348
00:15:47,090 --> 00:15:50,626
I know your math skills.
They blow.
349
00:15:50,660 --> 00:15:52,662
Touché.
350
00:15:52,695 --> 00:15:54,797
You sound very familiar.
351
00:15:54,830 --> 00:15:57,767
Why did you publish it
in an obscure journal in India?
352
00:15:57,800 --> 00:15:59,435
Why not publish in
353
00:15:59,469 --> 00:16:02,305
Really Really Cool Head Cases
of South Philly?
354
00:16:02,338 --> 00:16:06,076
Neuroscience New Delhi
is a respected journal.
355
00:16:06,109 --> 00:16:07,477
Yeah, the guy running
Slurp 'N' Gulp
356
00:16:07,510 --> 00:16:08,778
tells me it's one
of the best.
357
00:16:08,811 --> 00:16:10,613
Get a hooker.
Anything.
358
00:16:10,646 --> 00:16:13,483
See, I'm thinking that
publishing studies
359
00:16:13,516 --> 00:16:15,518
is probably the easiest way
to get a pharmaceutical company
360
00:16:15,551 --> 00:16:16,652
to give you a reach-around.
361
00:16:16,686 --> 00:16:20,190
And choosing a journal
that no one can actually read,
362
00:16:20,223 --> 00:16:21,457
well, that's,
that's shrewd.
363
00:16:21,491 --> 00:16:22,658
I know I know you.
364
00:16:22,692 --> 00:16:24,427
Sure you do.
365
00:16:24,460 --> 00:16:25,728
Dick.
366
00:16:25,761 --> 00:16:27,097
The name's Philip.
367
00:16:27,130 --> 00:16:28,764
Oh, my bad.
368
00:16:28,798 --> 00:16:30,333
Something to do
with your face.
369
00:16:30,366 --> 00:16:31,701
I always think
your name is Dick.
370
00:16:31,734 --> 00:16:33,603
House?
371
00:16:33,636 --> 00:16:36,406
Here.
372
00:16:36,439 --> 00:16:38,441
Medical school was
20 years ago.
373
00:16:38,474 --> 00:16:39,775
Give it a rest,
374
00:16:39,809 --> 00:16:40,810
grow up.
375
00:16:40,843 --> 00:16:42,178
Yeah, you were always
the grown-up,
376
00:16:42,212 --> 00:16:43,546
do the responsible thing.
377
00:16:43,579 --> 00:16:44,814
Tattletale.
378
00:16:44,847 --> 00:16:46,582
You cheated.
379
00:16:46,616 --> 00:16:48,251
I cheated then,
you're cheating now.
380
00:16:48,284 --> 00:16:50,420
Your drug doesn't work.
381
00:16:50,453 --> 00:16:51,754
Oh, yes, you would like
to believe that,
382
00:16:51,787 --> 00:16:53,289
because it plays right
into your fantasy--
383
00:16:53,323 --> 00:16:54,290
I tested it.
384
00:16:54,324 --> 00:16:55,658
Oh, really?
385
00:16:55,691 --> 00:16:56,792
What are your parameters?
386
00:16:56,826 --> 00:17:00,863
Where's your study?
387
00:17:00,896 --> 00:17:02,732
Room 2134.
388
00:17:02,765 --> 00:17:04,334
One patient?
389
00:17:04,367 --> 00:17:06,569
The coma patient?
390
00:17:06,602 --> 00:17:08,771
You haven't changed a bit.
391
00:17:08,804 --> 00:17:11,207
You took short cuts
in med school,
392
00:17:11,241 --> 00:17:13,376
you're taking short cuts now.
393
00:17:13,409 --> 00:17:16,179
You cannot test this
on an abnormal brain.
394
00:17:16,212 --> 00:17:18,448
That's so closed-minded.
395
00:17:18,481 --> 00:17:21,117
He's not abnormal,
he's special.
396
00:17:21,151 --> 00:17:24,754
Cerebral cortex atrophies
in coma patients.
397
00:17:24,787 --> 00:17:28,558
You need live,
conscious people.
398
00:17:32,328 --> 00:17:34,330
You don't know everything,
House.
399
00:17:38,768 --> 00:17:41,904
(Foreman)
It's something that disrupts
brain function.
400
00:17:41,937 --> 00:17:43,706
Plaques are perfect.
401
00:17:43,739 --> 00:17:45,775
Interrupt neuronal
communication.
402
00:17:45,808 --> 00:17:46,976
M.S.?
No.
403
00:17:47,009 --> 00:17:49,479
(Foreman)
M.S. is complicated.
I think this is more basic.
404
00:17:49,512 --> 00:17:51,881
It's just tachycardia
and seizures.
405
00:17:51,914 --> 00:17:53,383
How much longer
the burn unit guys
406
00:17:53,416 --> 00:17:54,917
gonna keep him in that thing?
407
00:17:54,950 --> 00:17:56,552
Lecture's over.
Let's go.
408
00:17:56,586 --> 00:17:58,854
House wants to...
409
00:18:00,690 --> 00:18:01,824
Adam's waking up.
410
00:18:01,857 --> 00:18:05,395
Get the anesthesiologist
in here now.
411
00:18:05,428 --> 00:18:06,896
(Cameron)
He's in pain.
412
00:18:06,929 --> 00:18:09,165
That's not pain.
413
00:18:09,199 --> 00:18:12,368
Need some help in here.
414
00:18:12,402 --> 00:18:15,905
[moans and gasps]
415
00:19:13,863 --> 00:19:15,865
Adam had an orgasm.
416
00:19:15,898 --> 00:19:22,272
What?
You mean while he was--
417
00:19:22,305 --> 00:19:23,639
Oh!
418
00:19:23,673 --> 00:19:25,775
God!
419
00:19:25,808 --> 00:19:27,777
What's wrong?
420
00:19:27,810 --> 00:19:32,482
I'm having a migraine.
421
00:19:32,515 --> 00:19:33,549
Are you okay?
422
00:19:33,583 --> 00:19:37,620
Uh, yes.
423
00:19:37,653 --> 00:19:40,923
I was right.
424
00:19:40,956 --> 00:19:43,759
Oh!
425
00:19:47,797 --> 00:19:49,299
Uh!
426
00:19:51,033 --> 00:19:52,935
I'm gonna knock you out
for a couple of hours.
427
00:19:52,968 --> 00:19:55,004
No, I got work to do.
428
00:19:55,037 --> 00:19:58,274
Just gimme sumatriptan
for the pain
429
00:19:58,308 --> 00:20:04,013
and verapamil
so it doesn't recur.
430
00:20:04,046 --> 00:20:07,750
I heard the patient had fun
in the hyperbaric chamber.
431
00:20:07,783 --> 00:20:08,918
Yeah.
432
00:20:08,951 --> 00:20:11,354
Gotta schedule me
some time in there.
433
00:20:13,389 --> 00:20:17,293
[scoffs]
Weber's meds aren't even
legal in the U.S.
434
00:20:17,327 --> 00:20:19,329
It's legal in India.
435
00:20:19,362 --> 00:20:22,264
I was disoriented.
436
00:20:28,371 --> 00:20:30,640
Um, moving around
is a bad idea.
437
00:20:30,673 --> 00:20:32,942
Hey, if you feel chest pain,
you need to let me know.
438
00:20:32,975 --> 00:20:35,511
Verapamil can cause congestive
heart failure.
439
00:20:35,545 --> 00:20:38,314
Nothing can hurt my heart.
440
00:20:40,550 --> 00:20:44,487
Hey, you're gonna feel
some dizziness.
441
00:20:44,520 --> 00:20:46,322
Definitely gonna
be constipated.
442
00:20:50,826 --> 00:20:55,398
Differential diagnosis
for getting off.
443
00:20:55,431 --> 00:20:56,832
Is he gonna be okay?
444
00:20:56,866 --> 00:20:58,868
No, something's seriously
wrong with him.
445
00:20:58,901 --> 00:21:03,839
Differential diagnosis
for ejaculation.
446
00:21:05,408 --> 00:21:07,042
Don't make me say it again.
447
00:21:07,076 --> 00:21:09,745
We're not stalling,
we just don't know.
448
00:21:09,779 --> 00:21:10,913
Then guess.
449
00:21:10,946 --> 00:21:13,616
Could pain medication
cause an orgasm?
450
00:21:13,649 --> 00:21:14,850
I wish.
451
00:21:14,884 --> 00:21:16,552
Maybe pain
caused the orgasm.
452
00:21:16,586 --> 00:21:19,355
You get a tattoo,
the brain releases endorphins
453
00:21:19,389 --> 00:21:20,756
which create pleasure.
454
00:21:20,790 --> 00:21:23,058
Most people don't orgasm
from a needle prick.
455
00:21:23,092 --> 00:21:24,627
(House)
Well, Chase has a point.
456
00:21:24,660 --> 00:21:27,730
The brain is like
a huge train station.
457
00:21:27,763 --> 00:21:31,100
If the switches--
Ow.
458
00:21:31,133 --> 00:21:33,903
You're the neurologist,
talk for me.
459
00:21:33,936 --> 00:21:35,838
If sensory information
got misinterpreted
460
00:21:35,871 --> 00:21:37,473
by the medial
forebrain bundle,
461
00:21:37,507 --> 00:21:39,041
it's possible for bad
to feel good
462
00:21:39,074 --> 00:21:40,543
and good to feel bad.
463
00:21:40,576 --> 00:21:42,445
He's a lucky kid.
464
00:21:42,478 --> 00:21:44,380
Let's not fix him
until the burns heal.
465
00:21:44,414 --> 00:21:46,649
So what attacks the medial
forebrain bundle?
466
00:21:46,682 --> 00:21:49,118
Infective neuropathies.
Vasculitic neuropathies.
467
00:21:49,151 --> 00:21:51,687
Krabbe's disease,
metachromatic leukodystrophy.
468
00:21:51,721 --> 00:21:54,056
(House)
All very bad things.
469
00:21:54,089 --> 00:21:56,959
No way to look for any of them
in his condition.
470
00:21:56,992 --> 00:21:58,127
Could be an infection.
471
00:21:58,160 --> 00:22:00,396
I said infection
about eight seconds ago.
472
00:22:00,430 --> 00:22:03,065
You listed
some brain infections.
473
00:22:03,098 --> 00:22:05,034
But what if it's just
a regular old infection
474
00:22:05,067 --> 00:22:06,636
festering in the burned skin?
475
00:22:06,669 --> 00:22:09,038
Pus on his arm isn't causing
problems in the forebrain.
476
00:22:09,071 --> 00:22:12,742
He's on 20 different medications
to manage his pain, his heart,
477
00:22:12,775 --> 00:22:14,744
how often he urinates.
478
00:22:14,777 --> 00:22:16,946
His brain is like a waiter
that's got too many--
479
00:22:16,979 --> 00:22:18,448
Hey, hey.
480
00:22:18,481 --> 00:22:21,083
I do the metaphors.
481
00:22:21,116 --> 00:22:23,753
[sighs]
The brain is stressed.
482
00:22:23,786 --> 00:22:25,988
An infection elsewhere could
put it over the edge.
483
00:22:26,021 --> 00:22:29,091
So we just wait for his burns
to heal to see if you're right?
484
00:22:29,124 --> 00:22:31,126
If you're wrong, he doesn't have
that kind of time.
485
00:22:31,160 --> 00:22:35,831
Dominic Larrey.
486
00:22:35,865 --> 00:22:38,100
He another dead doctor?
487
00:22:38,133 --> 00:22:41,136
He was Napoleon's
Surgeon in Chief.
488
00:22:41,170 --> 00:22:42,905
Cleaned a lot of battle wounds.
489
00:22:42,938 --> 00:22:44,540
By amputating legs.
490
00:22:44,574 --> 00:22:47,009
And with bugs.
491
00:22:49,912 --> 00:22:54,550
Maggots are implanted
directly into Adam's burns.
492
00:22:54,584 --> 00:22:57,953
Maggots--eat dead people.
I--
493
00:22:57,987 --> 00:22:59,522
Maggots eat dead flesh.
494
00:22:59,555 --> 00:23:02,191
Only dead flesh.
495
00:23:02,224 --> 00:23:06,696
So they're perfectly suited
to clean wounds.
496
00:23:06,729 --> 00:23:09,599
They also kill the bacteria
that thrive in injured tissues.
497
00:23:38,894 --> 00:23:41,631
Ho!
498
00:23:45,601 --> 00:23:48,003
Dr. Jekyll, I presume,
499
00:23:48,037 --> 00:23:49,705
they found a half-eaten sheep
in the zoo.
500
00:23:49,739 --> 00:23:52,041
The police want to ask you
a few questions.
501
00:23:52,074 --> 00:23:53,108
I need something
to wash it down.
502
00:23:53,142 --> 00:23:54,744
Coffee?
503
00:23:54,777 --> 00:23:55,945
Bad idea.
504
00:23:55,978 --> 00:23:57,613
You're better off with water!
505
00:23:57,647 --> 00:24:00,149
Coffee's closer.
506
00:24:00,182 --> 00:24:02,217
Foolproof plan, by the way.
507
00:24:02,251 --> 00:24:06,589
Either his meds would work,
and you'd be in psychic pain,
508
00:24:06,622 --> 00:24:09,191
because Von Evil
is gonna be rich.
509
00:24:09,224 --> 00:24:12,762
Or they wouldn't,
510
00:24:12,795 --> 00:24:14,096
and you get to be
in agony all day.
511
00:24:14,129 --> 00:24:15,965
[silverware falls]
512
00:24:15,998 --> 00:24:17,132
Perfect lose/lose situation.
513
00:24:17,166 --> 00:24:18,701
Very you.
514
00:24:18,734 --> 00:24:19,769
I had to prove--
515
00:24:19,802 --> 00:24:22,137
You proved nothing.
516
00:24:22,171 --> 00:24:24,073
Right.
517
00:24:24,106 --> 00:24:27,076
This isn't a migraine.
518
00:24:27,109 --> 00:24:29,779
Yeah, Dear New England
Journal of Medicine,
519
00:24:29,812 --> 00:24:32,181
I took this guy's drug,
and still got a headache.
520
00:24:32,214 --> 00:24:35,685
Thus scientifically proving
that my arch enemy is an idiot.
521
00:24:35,718 --> 00:24:37,319
You just wanted the pain.
522
00:24:37,352 --> 00:24:40,890
The meds are supposed
to prevent migraine.
523
00:24:40,923 --> 00:24:42,925
You get distracted by pain.
524
00:24:42,958 --> 00:24:45,194
Leaves less room for the things
you don't wanna think about.
525
00:24:45,227 --> 00:24:48,798
Like the Flyers sucking,
or the price of gas,
526
00:24:48,831 --> 00:24:52,167
or, oh, the fact that you pushed
the love of your life
527
00:24:52,201 --> 00:24:52,935
out of your life.
528
00:24:52,968 --> 00:24:54,970
God, I wish the pain
would go away.
529
00:24:55,004 --> 00:24:56,906
Next time you need to get
your mind off her,
530
00:24:56,939 --> 00:24:58,173
stick a needle in your eye.
531
00:24:58,207 --> 00:25:01,777
It's less annoying to the rest
of us when you can still walk.
532
00:25:09,151 --> 00:25:13,222
(Cameron)
Did you sleep here?
533
00:25:13,255 --> 00:25:16,258
Lower.
534
00:25:16,291 --> 00:25:18,027
[whispers]
Do you want a pillow?
535
00:25:18,060 --> 00:25:21,997
Not softer, lower.
536
00:25:22,031 --> 00:25:24,166
The frequency of your voice
is grating.
537
00:25:24,199 --> 00:25:26,301
You should've been
better by now.
538
00:25:26,335 --> 00:25:29,071
I'm super.
The patient?
539
00:25:29,104 --> 00:25:32,041
The maggots did great
for the burn.
540
00:25:32,074 --> 00:25:34,877
But the brainwaves are still
all over the map.
541
00:25:34,910 --> 00:25:37,146
Which means your regular
old infection
542
00:25:37,179 --> 00:25:38,981
isn't causing
his brain dysfunction.
543
00:25:39,014 --> 00:25:41,250
Which means there's
an underlying condition.
544
00:25:41,283 --> 00:25:43,385
Which means we gotta get
inside his head.
545
00:25:43,418 --> 00:25:45,855
Do a lumbar puncture.
546
00:25:45,888 --> 00:25:48,991
We've already established that
we can't get a lumbar--
547
00:25:49,024 --> 00:25:50,392
C2, C3.
548
00:25:50,425 --> 00:25:52,662
No, no, no way.
549
00:25:52,695 --> 00:25:54,830
I only saw a cervical tap once,
550
00:25:54,864 --> 00:25:55,898
and that guy got paralyzed.
551
00:25:55,931 --> 00:25:58,834
Ask the parents if they prefer
to have their son
552
00:25:58,868 --> 00:26:01,136
in a wheelchair, or dead.
553
00:26:05,207 --> 00:26:08,277
Something's causing his brain
to lose control.
554
00:26:08,310 --> 00:26:10,245
Eventually it will shut off.
555
00:26:10,279 --> 00:26:12,081
We need to do
a lumbar puncture
556
00:26:12,114 --> 00:26:15,150
to get some of the fluid
in his spine so we can test it.
557
00:26:15,184 --> 00:26:16,251
You need us
to sign a consent?
558
00:26:16,285 --> 00:26:19,088
I have to warn you.
559
00:26:19,121 --> 00:26:21,356
There's a serious risk
of paralysis or death.
560
00:26:21,390 --> 00:26:24,026
Are you saying
we shouldn't do this?
561
00:26:24,059 --> 00:26:26,428
You have to do this.
562
00:26:26,461 --> 00:26:27,997
Then why are you telling us
what can go wrong?
563
00:26:28,030 --> 00:26:29,965
I just think you should know.
564
00:26:29,999 --> 00:26:31,734
Either you're cruel or this
clipboard is a way for you
565
00:26:31,767 --> 00:26:33,736
to cover your ass
in case you cripple our son.
566
00:26:33,769 --> 00:26:35,037
This isn't his fault--
567
00:26:35,070 --> 00:26:35,805
No, it's not, it's yours.
568
00:26:35,838 --> 00:26:38,007
That's what you keep
telling me.
569
00:26:38,040 --> 00:26:39,408
My son is lying
in there half dead.
570
00:26:39,441 --> 00:26:41,811
I am just trying to find
a way to get through this.
571
00:26:41,844 --> 00:26:43,846
[signs paper]
I'm sorry.
572
00:26:43,879 --> 00:26:45,214
Yeah, I know.
573
00:26:48,117 --> 00:26:52,187
[monitor beeps]
574
00:27:04,834 --> 00:27:08,670
Needle.
575
00:27:20,983 --> 00:27:22,017
It's not going in.
576
00:27:22,051 --> 00:27:24,019
Don't force it.
577
00:27:24,053 --> 00:27:25,420
I'm going one space higher.
578
00:27:25,454 --> 00:27:29,158
It's too close to his
brain stem, it'll herniate.
579
00:27:29,191 --> 00:27:30,960
You're gonna paralyze him.
Not helping.
580
00:27:30,993 --> 00:27:32,995
[monitor beeps rapidly]
581
00:27:33,028 --> 00:27:34,163
His blood pressure's spiking.
Stop.
582
00:27:34,196 --> 00:27:35,430
I can get it.
583
00:27:35,464 --> 00:27:39,134
He's 180 over 120.
He's gonna stroke.
584
00:27:39,168 --> 00:27:41,036
I'm in the space.
Gimme the vial.
585
00:27:41,070 --> 00:27:44,106
[monitor beeps continue]
586
00:27:48,510 --> 00:27:52,114
[monitor beeps steady]
587
00:27:58,821 --> 00:28:01,423
He doesn't have M.S.
or an infection.
588
00:28:01,456 --> 00:28:05,360
His proteins aren't elevated?
589
00:28:05,394 --> 00:28:08,764
Wrong protein.
IgM, not IgG.
590
00:28:08,798 --> 00:28:12,267
Elevation was probably caused
by the bleeding.
591
00:28:12,301 --> 00:28:15,304
What if there was tingling
in his extremities
592
00:28:15,337 --> 00:28:17,039
prior to the crash?
593
00:28:17,072 --> 00:28:19,241
How can you still be on M.S.?
594
00:28:19,274 --> 00:28:21,243
You gotta be on something.
595
00:28:21,276 --> 00:28:25,014
Something's interrupting
his neurons' chit-chat.
596
00:28:25,047 --> 00:28:26,215
Like lesions.
597
00:28:26,248 --> 00:28:27,416
We can't scan for them.
598
00:28:27,449 --> 00:28:29,284
Only test we can do
we just did,
599
00:28:29,318 --> 00:28:30,385
and it was negative.
600
00:28:30,419 --> 00:28:33,355
He has no tingling,
no numbness.
601
00:28:33,388 --> 00:28:35,390
You read his history.
Parents didn't say anything--
602
00:28:35,424 --> 00:28:37,259
What about Adam?
603
00:28:37,292 --> 00:28:39,929
We can't look into his brain,
604
00:28:39,962 --> 00:28:41,463
but you want us
to read his mind?
605
00:28:41,496 --> 00:28:44,366
Good point.
606
00:28:49,504 --> 00:28:51,941
[door slides open]
607
00:28:51,974 --> 00:28:57,246
Yeah, you can finish
the sponge bath in a minute.
608
00:28:57,279 --> 00:28:59,014
They're just redoing
his dressings.
609
00:28:59,048 --> 00:29:00,415
He's out, he's fine.
610
00:29:00,449 --> 00:29:02,284
I didn't page you
to put him out,
611
00:29:02,317 --> 00:29:04,820
I paged you to wake him up.
612
00:29:04,854 --> 00:29:07,256
Why are these lights
so damn bright?
613
00:29:07,289 --> 00:29:09,124
Thank you.
614
00:29:09,158 --> 00:29:11,226
Come on,
I need to talk to him.
615
00:29:11,260 --> 00:29:14,129
House, you can't wake up a burn
victim to play 20 Questions.
616
00:29:14,163 --> 00:29:15,998
It's torture.
He won't remember.
617
00:29:16,031 --> 00:29:18,367
He's gonna be
in extraordinary pain--
God, you're good.
618
00:29:18,400 --> 00:29:19,835
You're putting me to sleep.
619
00:29:19,869 --> 00:29:21,904
I know he's gonna
be in pain,
620
00:29:21,937 --> 00:29:25,507
I know you disapprove,
I'm his attending, wake him up.
621
00:29:43,525 --> 00:29:46,261
Mmm...Oh, my God.
622
00:29:46,295 --> 00:29:47,562
I'm Dr. House.
623
00:29:47,596 --> 00:29:49,064
[shivering]
It hurts!
624
00:29:49,098 --> 00:29:51,033
It's gonna get a lot worse,
so answer fast.
625
00:29:51,066 --> 00:29:52,434
Before the accident,
626
00:29:52,467 --> 00:29:53,568
did you experience any numbness
627
00:29:53,602 --> 00:29:55,137
any tingling in your fingers?
628
00:29:55,170 --> 00:29:56,471
[screams and moans]
629
00:29:56,505 --> 00:29:58,273
You got burnt, it's healing,
I need an answer.
630
00:29:58,307 --> 00:29:59,408
It really hurts!
631
00:29:59,441 --> 00:30:01,543
Any tingling in your
arms or legs?
632
00:30:01,576 --> 00:30:03,245
Do something!
I can't--
633
00:30:03,278 --> 00:30:06,248
Adam, you gotta listen to me.
Did you feel anything?
634
00:30:06,281 --> 00:30:08,117
[screams]
635
00:30:08,150 --> 00:30:13,088
I pissed my pants and then
I don't...remember--
636
00:30:16,425 --> 00:30:20,562
[loud scream]
637
00:30:21,997 --> 00:30:24,133
[moans]
638
00:30:52,094 --> 00:30:53,595
Is he okay?
639
00:30:53,628 --> 00:30:56,531
Get everyone in my office.
640
00:30:56,565 --> 00:30:58,533
Where are you going?
641
00:30:58,567 --> 00:31:00,402
Kid's screaming gave me
a headache.
642
00:31:00,435 --> 00:31:02,604
I gotta take an aspirin.
643
00:31:07,109 --> 00:31:10,079
[Get Miles by Gomez]
644
00:31:10,112 --> 00:31:18,120
*
645
00:32:01,463 --> 00:32:03,098
House.
646
00:32:03,132 --> 00:32:04,533
You okay?
We've been waiting for you.
647
00:32:08,537 --> 00:32:11,240
I'm hallucinating.
648
00:32:14,143 --> 00:32:17,646
Hallucinations with migraines
are pretty uncommon.
649
00:32:17,679 --> 00:32:19,048
What'd you see?
650
00:32:19,081 --> 00:32:22,017
I saw music.
651
00:32:22,051 --> 00:32:24,486
Sensory deception
makes no sense.
652
00:32:24,519 --> 00:32:26,688
Shh...
653
00:32:29,758 --> 00:32:32,194
[voice distorted]
You took something.
654
00:32:32,227 --> 00:32:34,629
The kid's fighting
for his life.
655
00:32:34,663 --> 00:32:36,631
[Cameron's voice echoing]
656
00:32:36,665 --> 00:32:40,069
*
657
00:32:40,102 --> 00:32:42,504
* Get miles away
658
00:32:42,537 --> 00:32:45,607
* Get miles away
659
00:32:45,640 --> 00:32:48,310
* Get miles away
660
00:32:48,343 --> 00:32:51,313
* Get miles away
661
00:32:51,346 --> 00:32:54,116
* Get miles away
662
00:32:54,149 --> 00:32:57,119
* Get miles away
663
00:32:57,152 --> 00:33:00,389
* Get miles *
664
00:33:05,360 --> 00:33:07,329
Hey, you find him?
665
00:33:07,362 --> 00:33:08,830
He was hallucinating
in the locker room.
666
00:33:08,863 --> 00:33:10,599
He okay?
667
00:33:10,632 --> 00:33:12,234
He's feeling no pain,
he's high.
668
00:33:12,267 --> 00:33:14,603
Vicodin high?
Past that.
669
00:33:14,636 --> 00:33:17,406
He's seeing sounds.
Took something.
670
00:33:17,439 --> 00:33:19,141
[blinds shudder]
671
00:33:20,775 --> 00:33:22,311
(House)
Why is it so dark in here?
672
00:33:22,344 --> 00:33:23,712
Beautiful day outside.
673
00:33:23,745 --> 00:33:26,515
Open the shades.
Let the sunshine in.
674
00:33:26,548 --> 00:33:29,384
It's nighttime.
675
00:33:29,418 --> 00:33:31,286
It's still Tuesday, right?
676
00:33:31,320 --> 00:33:32,754
You look better.
677
00:33:32,787 --> 00:33:34,523
I took something.
678
00:33:34,556 --> 00:33:36,291
Mind if I ask what?
679
00:33:36,325 --> 00:33:39,561
Uh, little of this,
little of that.
680
00:33:39,594 --> 00:33:41,496
I know what's wrong
with our patient.
681
00:33:41,530 --> 00:33:42,831
He's depressed.
682
00:33:42,864 --> 00:33:44,666
He told you that
when you woke him up?
683
00:33:44,699 --> 00:33:47,236
No, he told me he pissed
his pants and blacked out.
684
00:33:47,269 --> 00:33:48,503
That's not a diagnostic
of depression.
685
00:33:48,537 --> 00:33:50,605
Lack of appetite.
Isolating yourself--
686
00:33:50,639 --> 00:33:52,307
Uncontrollable urination
and blacking out
687
00:33:52,341 --> 00:33:53,275
are good predictors of what?
688
00:33:53,308 --> 00:33:54,476
Seizure.
689
00:33:54,509 --> 00:33:56,478
Which means the seizure he had
when you tested his heart
690
00:33:56,511 --> 00:33:57,846
was at least
his second seizure.
691
00:33:57,879 --> 00:34:01,450
So what? Depression and seizures
aren't correlated.
692
00:34:01,483 --> 00:34:03,518
No, but you know what is?
693
00:34:03,552 --> 00:34:05,587
Depression and anti-depression
medicine.
694
00:34:05,620 --> 00:34:07,489
Tox screen was clean.
695
00:34:07,522 --> 00:34:09,858
Yeah, but you know how much crap
he's got in his system
696
00:34:09,891 --> 00:34:11,626
for dealing with those burns.
697
00:34:11,660 --> 00:34:13,162
The guy could have
the Spanish Armada
698
00:34:13,195 --> 00:34:14,363
floating through
his bloodstream,
699
00:34:14,396 --> 00:34:15,430
we wouldn't know about it,
700
00:34:15,464 --> 00:34:17,132
'til they started firing
cannons.
701
00:34:17,166 --> 00:34:19,401
Antidepressants have been known
to cause seizures in kids,
702
00:34:19,434 --> 00:34:20,635
but not orgasms.
703
00:34:20,669 --> 00:34:21,836
This is a brain in trouble.
704
00:34:21,870 --> 00:34:25,240
This is a brain
with too much serotonin.
705
00:34:25,274 --> 00:34:27,142
Serotonin affects mood,
appetite.
706
00:34:27,176 --> 00:34:28,777
It doesn't cause
a brain to shut down.
707
00:34:28,810 --> 00:34:30,845
Antidepressants fake brains
into thinking
708
00:34:30,879 --> 00:34:33,482
they have more serotonin
than they actually do.
709
00:34:33,515 --> 00:34:37,319
Every 10 million or so cases,
it sets off a chain reaction.
710
00:34:37,352 --> 00:34:39,888
It produces too much,
enough to fry itself.
711
00:34:39,921 --> 00:34:42,591
If Adam has Serotonin Storm,
it's deadly.
712
00:34:42,624 --> 00:34:44,693
But treatable.
Cyproheptadine.
713
00:34:44,726 --> 00:34:46,495
Unless he doesn't have
Serotonin Storm.
714
00:34:46,528 --> 00:34:48,663
He could just as easily have
too much dopamine as serotonin.
715
00:34:48,697 --> 00:34:49,931
But if it's dopamine,
716
00:34:49,964 --> 00:34:51,733
the cyproheptadine
will kill him.
717
00:34:51,766 --> 00:34:53,468
Where are you going?
718
00:34:53,502 --> 00:34:55,404
I'm gonna talk to the kid again.
Seems nice.
719
00:34:55,437 --> 00:34:56,605
You can't.
720
00:34:56,638 --> 00:34:58,607
Why? Did he say
he doesn't like me?
721
00:34:58,640 --> 00:35:00,942
The anesthesiologist
told the parents what you did.
722
00:35:00,975 --> 00:35:02,311
[House scoffs]
723
00:35:02,344 --> 00:35:04,646
Everyone's a tattletale.
724
00:35:09,651 --> 00:35:12,621
Is your son depressed?
725
00:35:12,654 --> 00:35:14,489
No, who are you?
726
00:35:14,523 --> 00:35:16,625
I'm Dr. House.
727
00:35:16,658 --> 00:35:19,528
Oh, you're the idiot who--
I heard him screaming
all the way down the hallway.
728
00:35:19,561 --> 00:35:20,495
If I didn't wake him up,
729
00:35:20,529 --> 00:35:22,531
I wouldn't have learned
what caused the crash.
730
00:35:22,564 --> 00:35:25,234
I think he had a seizure.
731
00:35:25,267 --> 00:35:29,971
Th-this wasn't my fault?
732
00:35:30,004 --> 00:35:31,673
Well, if he hadn't had
the brain problem,
733
00:35:31,706 --> 00:35:33,208
he wouldn't have the burns.
734
00:35:33,242 --> 00:35:34,209
On the other hand,
735
00:35:34,243 --> 00:35:35,644
if you hadn't put him
on the ATV,
736
00:35:35,677 --> 00:35:36,811
he also wouldn't have
the burns.
737
00:35:36,845 --> 00:35:39,614
You can debate your personal
responsibility after I leave.
738
00:35:39,648 --> 00:35:41,216
I need to wake him up again.
739
00:35:41,250 --> 00:35:43,218
I need to know if he's taking
anti-depressants.
740
00:35:43,252 --> 00:35:44,819
He's not.
741
00:35:44,853 --> 00:35:46,655
He's the happiest kid I know.
742
00:35:46,688 --> 00:35:47,789
But you don't know, do you?
743
00:35:50,692 --> 00:35:51,993
He's my son.
744
00:35:52,026 --> 00:35:54,529
Mmm, that's sort of my point.
745
00:35:54,563 --> 00:35:56,631
At 16, they'll tell
anyone anything.
746
00:35:56,665 --> 00:35:57,899
Except their parents.
747
00:35:57,932 --> 00:35:59,834
Adam talks to us
about everything.
748
00:35:59,868 --> 00:36:01,836
Yeah, I know about the pot
and the cocaine.
749
00:36:01,870 --> 00:36:03,838
There was never cocaine--
750
00:36:03,872 --> 00:36:07,476
You sure?
You having him followed?
751
00:36:07,509 --> 00:36:09,744
He told us when he got
drunk at a party.
752
00:36:09,778 --> 00:36:11,580
He told us when he started
having sex.
753
00:36:11,613 --> 00:36:13,548
16, way to go.
754
00:36:13,582 --> 00:36:15,450
He told us when he cheated
on a math test.
755
00:36:15,484 --> 00:36:17,352
He told us when his girlfriend
cheated on him.
756
00:36:17,386 --> 00:36:19,388
He doesn't hide
anything from us.
757
00:36:19,421 --> 00:36:20,622
But if he was depressed?
758
00:36:20,655 --> 00:36:22,491
He'd tell us.
759
00:36:22,524 --> 00:36:24,659
We don't judge.
He's not depressed, we're sure.
760
00:36:24,693 --> 00:36:28,830
"Bet his life on it" sure?
761
00:36:28,863 --> 00:36:30,432
Just hypothetically.
762
00:36:30,465 --> 00:36:33,234
Yeah.
763
00:36:35,804 --> 00:36:39,040
Okay.
764
00:36:39,073 --> 00:36:42,477
Kid's happy.
765
00:36:42,511 --> 00:36:45,680
Happy, happy, happy.
766
00:36:45,714 --> 00:36:47,015
Then we're back to where
we started,
767
00:36:47,048 --> 00:36:48,617
seizure disorders.
768
00:36:48,650 --> 00:36:52,554
Seizure disorders
aren't causing orgasms.
769
00:36:52,587 --> 00:36:53,555
Vascular malformations.
770
00:36:53,588 --> 00:36:56,057
Would've seen it
on the sonogram.
771
00:36:56,090 --> 00:36:57,459
Hepatic encephalopathy?
772
00:36:57,492 --> 00:37:00,529
Liver enzyme tests were normal.
773
00:37:06,034 --> 00:37:07,502
Where are you going?
774
00:37:07,536 --> 00:37:09,504
Take a leak.
775
00:37:15,977 --> 00:37:18,880
What are you doing?
Can't come in here.
776
00:37:18,913 --> 00:37:19,981
You're not sterile.
777
00:37:20,014 --> 00:37:21,750
Don't touch our son,
we told you.
778
00:37:21,783 --> 00:37:24,586
Seriously, millions of bacteria,
microbes on you.
779
00:37:24,619 --> 00:37:25,620
He'll die of sepsis.
780
00:37:25,654 --> 00:37:28,523
If you go in there...
781
00:37:30,559 --> 00:37:32,527
I think he's gonna
wake him up again.
782
00:37:32,561 --> 00:37:34,295
I know he is.
783
00:37:35,930 --> 00:37:38,099
House, you can't do this.
784
00:37:38,132 --> 00:37:40,535
Oh, if I had a nickel
for every time I've heard that.
785
00:37:40,569 --> 00:37:43,572
Relax. They gonna sue us?
786
00:37:43,605 --> 00:37:45,807
If I'm right,
I save his life.
787
00:37:45,840 --> 00:37:48,410
If I'm wrong, he's dead
no matter what I do.
788
00:37:48,443 --> 00:37:49,944
Either way,
789
00:37:49,978 --> 00:37:51,713
how much have I really
hurt them?
790
00:37:51,746 --> 00:37:53,515
(Emily)
Leave him alone!
791
00:37:53,548 --> 00:37:55,550
You're not sterile.
You wanna kill the kid?
792
00:37:55,584 --> 00:37:56,918
Give me the syringe.
793
00:37:56,951 --> 00:37:58,387
No pain, no gain.
794
00:37:58,420 --> 00:38:02,591
Hey, you gotta stop this.
795
00:38:02,624 --> 00:38:04,993
You're right.
796
00:38:05,026 --> 00:38:07,729
He's not depressed.
797
00:38:07,762 --> 00:38:09,631
Yeah, sure.
798
00:38:09,664 --> 00:38:11,566
I'm not letting you go
until you give me that syringe.
799
00:38:11,600 --> 00:38:14,969
What's that on his wrist?
800
00:38:15,003 --> 00:38:16,371
(Foreman)
A burn.
801
00:38:16,405 --> 00:38:17,539
Why on his wrist?
802
00:38:17,572 --> 00:38:18,773
Why not on his wrist?
803
00:38:18,807 --> 00:38:21,476
His back, his torso,
everything's a mess.
804
00:38:21,510 --> 00:38:23,978
His forearms are clean.
Except right there.
805
00:38:24,012 --> 00:38:26,014
(Foreman)
So what?
806
00:38:26,047 --> 00:38:27,849
It's a perfect circle.
807
00:38:27,882 --> 00:38:30,585
So a drop of burning gasoline
fell on his wrist.
808
00:38:30,619 --> 00:38:32,554
A screw from the ATV.
809
00:38:32,587 --> 00:38:34,355
Maybe.
810
00:38:43,197 --> 00:38:45,834
Why are you torturing him?
811
00:38:45,867 --> 00:38:47,669
Does your son smoke?
812
00:38:47,702 --> 00:38:49,671
I'd kill him.
813
00:38:49,704 --> 00:38:51,606
[sighs]
814
00:38:51,640 --> 00:38:54,543
So he talked to you
about sex, crack.
815
00:38:54,576 --> 00:38:56,978
Anything except cigarettes.
816
00:38:57,011 --> 00:38:59,648
He has a cigarette burn
on his wrist.
817
00:38:59,681 --> 00:39:04,686
And also a fading nicotine
stain between two fingers.
818
00:39:04,719 --> 00:39:07,756
Bad news, you son has
a filthy, unhealthy habit.
819
00:39:07,789 --> 00:39:10,191
Good news,
he's trying to quit.
820
00:39:10,224 --> 00:39:12,561
Bad news,
the quitting's killing him.
821
00:39:12,594 --> 00:39:14,463
Good news, I can cure him.
822
00:39:14,496 --> 00:39:16,130
Bad news...
823
00:39:16,164 --> 00:39:17,632
nope, that's the end of it.
824
00:39:17,666 --> 00:39:20,535
Quitting smoking can kill?
825
00:39:20,569 --> 00:39:23,705
No-smoke meds are
anti-depressants.
826
00:39:23,738 --> 00:39:25,607
The crappy ones you get
over the Internet.
827
00:39:25,640 --> 00:39:26,941
They're loaded with whatever
anti-depressants
828
00:39:26,975 --> 00:39:28,577
they can get cheap.
829
00:39:28,610 --> 00:39:29,844
Since Mommy and Daddy
830
00:39:29,878 --> 00:39:33,615
obviously didn't take him
to a pediatrician...
831
00:39:33,648 --> 00:39:38,119
Sorry, I was wrong about him
being depressed.
832
00:39:38,152 --> 00:39:41,556
Treat him.
833
00:39:57,772 --> 00:39:59,741
(Cuddy)
Hey.
834
00:39:59,774 --> 00:40:02,611
Did you drop acid?
835
00:40:02,644 --> 00:40:05,747
Why would I do that?
836
00:40:05,780 --> 00:40:07,716
To annoy me.
837
00:40:07,749 --> 00:40:09,651
Or maybe because
you're miserable.
838
00:40:09,684 --> 00:40:12,754
Or because you wanna
self-destruct.
839
00:40:12,787 --> 00:40:14,188
Pick one.
840
00:40:14,222 --> 00:40:18,660
How 'bout because LSD acts
on serotonin receptors
841
00:40:18,693 --> 00:40:22,764
in the brain, which can stop
a migraine in its tracks.
842
00:40:22,797 --> 00:40:24,533
I'm just saying it's also
a possibility.
843
00:40:24,566 --> 00:40:25,867
How did you know--
844
00:40:25,900 --> 00:40:28,603
Cameron is worried about you.
845
00:40:28,637 --> 00:40:30,739
I told her that LSD lasts
up to 12 hours.
846
00:40:30,772 --> 00:40:32,507
If you were functional,
she must be wrong.
847
00:40:32,541 --> 00:40:34,643
Either that, or I also took
a whole bunch
848
00:40:34,676 --> 00:40:38,079
of anti-depressants,
which short-circuited the LSD.
849
00:40:38,112 --> 00:40:39,614
I'm just saying that would
also explain it.
850
00:40:39,648 --> 00:40:41,650
Thank you for ruining
my clinical trials.
851
00:40:41,683 --> 00:40:43,985
Pharmaceutical company's
shutting me down.
852
00:40:44,018 --> 00:40:45,019
You're kidding, really?
853
00:40:45,053 --> 00:40:46,655
How could that surprise you?
854
00:40:46,688 --> 00:40:48,557
You sent them an email
complaining about my math.
855
00:40:48,590 --> 00:40:50,592
Telling them about
your stunt.
856
00:40:50,625 --> 00:40:52,627
I didn't know people
actually read emails.
857
00:40:52,661 --> 00:40:53,662
Delete button is
so conveniently located--
858
00:40:53,695 --> 00:40:55,229
So what's next?
859
00:40:55,263 --> 00:40:57,632
You gonna follow me
my whole life, torture me?
860
00:40:57,666 --> 00:40:58,733
Why would I do that?
861
00:40:58,767 --> 00:41:00,268
You waited 20 years
to do this.
862
00:41:00,301 --> 00:41:02,303
What's next?
Break up my marriage?
863
00:41:02,336 --> 00:41:06,174
No. We're even.
864
00:41:06,207 --> 00:41:08,677
Right.
865
00:41:08,710 --> 00:41:11,012
Oh, thanks for setting me up.
866
00:41:14,616 --> 00:41:18,553
Eye for an eye,
LSD, and antidepressants,
867
00:41:18,587 --> 00:41:20,922
everything in balance.
868
00:41:20,955 --> 00:41:22,624
Buddhists call it Karma,
869
00:41:22,657 --> 00:41:24,258
Christians call it
the Golden Rule,
870
00:41:24,292 --> 00:41:27,796
Jews call it...
871
00:41:27,829 --> 00:41:28,997
I don't know.
872
00:41:29,030 --> 00:41:31,666
Rabbi Hillel said
something poignant.
873
00:41:31,700 --> 00:41:34,669
Universe always
settles the score.
874
00:41:34,703 --> 00:41:36,571
Does it?
875
00:41:36,605 --> 00:41:39,941
No.
876
00:41:39,974 --> 00:41:44,078
But it should.
877
00:41:48,817 --> 00:41:50,785
(Doug)
Do you think you'll
ever be able
878
00:41:50,819 --> 00:41:52,821
to look at him
and not blame me?
879
00:41:52,854 --> 00:41:58,960
Yeah. Will you?
880
00:42:25,854 --> 00:42:27,722
[knock at door]
881
00:42:48,009 --> 00:42:50,645
I'm Paula.
882
00:42:50,679 --> 00:42:52,647
Hey, Paula.
883
00:42:52,681 --> 00:42:54,415
How you doing?
884
00:42:54,448 --> 00:42:56,050
You work over at the college?
885
00:42:56,084 --> 00:42:58,052
Or are you full time
over at--
886
00:42:58,086 --> 00:43:01,122
I'm looking
for a distraction.
887
00:43:01,155 --> 00:43:04,025
You don't need to talk
to do that, do you?
888
00:43:10,932 --> 00:43:13,935
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