Original subtitles

Where's this bleeding coming from?

Calcified iliac artery!

Simulation off!

Good.

24 July.

Waves of protest continue in Germany.

While Health Minister Nguyen divides the country

with the new healthcare reform,

the huge fires in the Czech Republic

are spreading rapidly towards Saxony.

The climate demonstrations have been joined

by reform protests for several days now.

The thrust: the reform is the end of solidarity.

Health Minister Nguyen is unimpressed by this.

The reform would consistently lead to a better

and fairer healthcare system,

- he said this morning in Berlin. - News off.

Good morning. It's six o' clock.

Current temperature: 32 degrees.

Your vital signs show no abnormalities.

The hydration index is 4.8.

Staying in a cooling zone between 11 a.m. and 8 p.m. is recommended.

Stop the reform! Stop the reform!

Hey! Hey! Stop the reform!

Stop the reform!

Hey! Hey!

Stop the reform!

What's going on here?

Stop the reform!

MORE CARE NOT LESS!

Stop the reform!

Emilia?

Maral. Where are you?

Get started, we'll be there in five minutes.

How can you still sleep at night?

How can you still sleep at night?

A warm welcome.

It fills me with great joy

that a very special woman

is returning to her alma mater, the Charité, today.

She's highly respected worldwide as a microbiologist

and bioinformatician.

Her professional career has taken her

to Zurich, Chicago, Shanghai

and most recently to Harvard Medical School in Boston.

The microbiome screening named after her

has since become a standard diagnostic tool

in clinics all over the world.

And now we welcome a very important guest:

our Minister of Health, Thomas Nguyen.

Thomas, the floor is yours.

You've introduced me as an important personality.

But I'm not that important.

My job is simply

to create the best conditions for top medical research.

I am particularly happy about Dr Safadi's new appointment,

because I value her not only for her excellent research,

but also because she actively advised us on healthcare reform.

Boo! Yeah, boo! It's true...

As Tolstoy said so beautifully,

"People would rather go down

before changing their habits".

Thank you.

How does this door open?

What do you think you're doing?

We're in a hurry.

No! Maral? Is that you?

Mrs Kachel!

- So nice to see you! - It can't be!

Hello, I'm Julia. Maral's wife.

- Nice to meet you. - I see.

And I thought you were part of the group of demonstrators!

Can you help us? Maral had to be in the auditorium five minutes ago.

I see you haven't changed since you were a student.

Yes, I'll make an exception this time.

There... Now show them!

- Thanks. - Thanks.

Thank you, Thomas. Yes...

Ah! And here she is,

the new head of the Institute of Microbiology at the Charité,

Dr Maral Safadi!

Always late but worth the wait!

Yes...

Let's not sugarcoat it.

I just have a terrible sense of time,

for which I...

apologise profusely.

I'm looking forward

to returning to the Charité after what feels like 100 years

and taking over as head of the Institute of Microbiology here.

I'll spare you the sentimentalities about how much

the Charité means to me as a native Berliner

and jump straight to my work.

Lights off.

We're not alone.

Our bodies

are colonised by up to 40 trillion viruses and bacteria.

On the skin. On our mucous membranes.

In our organs.

The totality of these microbes

forms our personal microbiome

as individual and unique

as our fingerprint.

The microbiome in our gut is particularly complex.

As around 80% of our immune system is located here,

the gut microbiome has a significant influence on our health.

If its balance is disturbed by harmful microbes, we get sick.

Now,

these findings are nothing new.

What is new, however, is my research approach:

the search for ways

to individually influence such a disturbed,

dysbiotic microbiome structure,

thus bringing it back into balance.

Only a few effective antibiotics are left for most infections.

- I'm going outside. - But we've

reached the point where we can cure

diseases such as neurodermatitis with microbiome therapy alone.

And I'm convinced

that its continued development

will enable us to develop

completely new treatment options,

thereby defeating numerous inflammatory diseases.

Tachycardia 110, hypotensive 80

to 40 mmHg, MAD below 65,

respiratory rate of 22, decreased vigilance.

OK. Severe sepsis.

How are you, Mr Baldwin?

- Not so good. - Why did Hamburg send him to us?

The infection is spreading unusually fast and they can't find anything.

Blood pressure is unstable. Quick.

He's stabilising.

Where are...

Where are Evelyn and Rupert?

Your relatives are being examined -

we need to be sure they haven't been infected by you.

I'm going to carefully scan you again now.

- Ah, damn it! - What is it?

Swollen lymph nodes.

The pathogen is spreading systemically.

- Call Dr Van Boeken. - Call Dr Van Boeken.

Dr Van Boeken is currently unavailable.

He's not answering.

Quick. His lungs are about to shut down.

Ah, there you are.

So, Mrs Abdul-Hai,

- are you ready for tomorrow? - Mmhmm, yes.

I cannot wait.

You're giving me a new lease of life.

Good.

I've already rehearsed your operation today

and I know what to look out for with you.

But your scoring...

"Patient refuses to cooperate actively in her recovery"?

Why haven't you been doing your treatment?

When, then?

I help my son in the shop all day

and sort parcels in the evening.

I have to go in for dialysis three times a week,

and the grandchildren come at the weekend.

The Safadi screening is good so far.

But your blood sugar...

No, no, no. That can't be right, doctor!

I don't eat sweets.

Well, just one a day.

The operation is in 24 hours.

It's very important

that you don't eat anything after midnight.

Especially no sweets. Can you manage that?

Yes, yes.

- Alright. - Yes, yes...

Then we're ready to go.

Yes, yes...

CHARITÉ - HEALING FOREST

To the luminary!

No more adulation, please?

I only became a politician for the adulation.

But you don't get that from everyone.

You mean my groupies?

- Groupies? - Yes, the demonstrators.

They follow me everywhere.

It's all part of the job.

As the saying goes: "He who will not sacrifice should not reform".

Louise von François.

Cin cin.

Excuse me for a moment.

Dylan?

- Hello, Maral. - So, have you settled in yet?

Oh, maybe not settled in yet, but we definitely arrived well.

- I'm glad. - Congrats!

A nice presentation.

If not very optimistic.

I would say I... love challenges

and I'm looking forward to our collaboration.

- Me too. - Excuse me.

I've been trying to reach you.

Ah, I was offline.

The patient from Hamburg-Eppendorf has arrived.

His inflammation is spreading unusually quickly.

Any pathogen?

No. We can't identify it.

We've never had a case like this before.

Sorry, Maral.

- I... I'll join you. - And your party?

Well, I'm not dressed up anyway.

Hey, work calls!

Right, let's go.

- You're the boss. - That's right.

I need to discuss something. I'll be right back.

Hmm?

This tastes awful.

I like kombucha.

Oh. It's strong.

- Er, by the way, I'm... - Dr Safadi's wife.

Some people also call me Julia Kowalczyk.

And you are?

Ferhat Williamson. Head of Neurotechnology.

Ah, a colleague! Nice.

I'm a gynaecologist from today.

Here... I'm working here as... a gynaecologist

from today.

Bye, then.

Let's see what our specialists say. His condition remains poor.

Er... This is Mrs and Mr Baldwin,

the spouses of Piet Baldwin.

Thank you, Dr Krasniqi.

Hello. I'm Dr van Boeken, this is Dr Safadi.

You already know our doctoral student Sheila Khan.

- Hello. - Hello, Mr Baldwin.

How are you feeling?

So the pathogen

has not yet been identified or cultivated?

- No. - What about the Safadi screening?

The inflammation signature shows

a bacterial infection with conspicuously strong inflammation

that started with the skin and has been spreading to

the internal organs since this morning.

The Safadi screening - you have something to do with it?

It's named after her.

She invented the algorithm.

OK, and what does it analyse?

The microorganisms

in the faeces, on the skin, in the mouth, the nose...

They tell us

whether the microbiome in the gut is healthy

or whether there's inflammation in the body.

It's like on our fields.

- Ah. Are you a farmer? - Yes.

Specialised in legumes.

Fertiliser rate?

Less than 2% thanks to coating.

And...

we're currently experimenting

with new...

bacterial strains directly on the...

root nodules

to achieve greater...

heat resistance...

for the plants.

So you're in the industry.

Mr Baldwin,

do you have a skin wound that has come into contact with the soil?

Erm... I...

I cut myself a few days ago chopping potatoes. But...

But only lightly on my finger.

The health department must take samples from the field.

Did you consume anything before the symptoms?

Possibly contaminated water...

- No. - The water supply was fine.

Otherwise we'd be sick too.

What will happen to Piet now?

First we'll have to find out

which bacterium caused the infection.

Don't worry.

- Your husband is in the best hands. - Thank you,

Dr Safadi.

Sheila, come with me.

Why are you doing a DNA sequencing

of the samples again? We already have the results from Hamburg.

And they couldn't find the pathogenic bacterium either.

That's why we have to cultivate it specifically.

Do you know if my things were already delivered?

Um...

At the front, I think.

There you are.

This incubator

can be used to create very specific growth conditions and interactions.

Did you build it yourself?

No, a colleague from Boston

made the prototype for me.

Let's see.

And...

Is this already the cultivated bacterium?

Yes. Very good.

What's that?

That's a strange profile.

- I've never seen one like this. - Nope.

Let's check it for susceptibilities.

It really is a completely new pathogen.

Resistant to all conventional antibiotics.

Well, then,

we'll have to programme it with one individually.

Hmm. That won't work.

But if there's a bacterial pathogen, then there's a suitable antibiotic.

We just have to find it.

AMBULANCE

The equipment storage room is over there.

The toilets are around the corner here,

and the operating theatre is on the left.

Wow, I hope I remember all that.

It's been a while since I worked in a hospital.

The building plan for your clip is activated by IT.

Good.

And what's this?

This is your first patient.

Aurelia Owanga. She doesn't speak German.

This is your pad.

- Have fun. - Thanks.

Good morning.

- Say good morning. - Good morning.

So...

Aurelia...

- Translator on. - Translator on.

Translator on.

So you want to have ovarian tissue removed?

My mum wants that.

She'll be 15 soon.

We have to do it now, or the insurance won't cover it.

But I'd rather do it later. Then I'll just pay for it myself.

That's also an option.

Of course, it would cost money

and the ovarian tissue quality would probably not be as good.

I don't even know if I want children.

I didn't either as a teenager.

And ten years later, I really wanted one.

But a less defiant one.

A desire to have children may come later.

Yeah, but she didn't have to decide that at 14.

Yes, having children is really a big question.

If you were to have the procedure,

you could come back to this question when it becomes relevant

for you.

How does the whole thing work?

We remove a quarter of your ovary

and freeze the tissue.

And if you want

to have children later on, we make this preserved ovary

produce new eggs

in a test tube. And then we reinsert them.

- And then another operation? - No.

The eggs are inserted transvaginally.

Don't be so dramatic.

Aurelia,

I'd like to show you something.

Will you come with me?

This is an airlock with UV light.

It disinfects us.

And here's the operating theatre.

- Do you prefer warm or cold light? - Warm.

What kind of music do you like?

I like classical music and rap.

Wow,

that's some sensitive speech recognition, huh?

Great.

It's my first day here today.

- Do you like the music? - Yes.

When I'm in the operating theatre,

I always play what my patients want.

It calms them.

Look at this.

This is how we do the anaesthetic.

You get an injection

and then you sleep for 30 minutes with the mask on...

Panic?

Open window. Come on. Let's breathe together.

In through the nose.

One, two, three, four.

And out through the mouth.

One, two, three, four. Once again.

One, two, three, four.

One, two, three, four.

Better?

I hate this fear. You absolutely cannot tell my mum about this.

Being afraid of surgery is not a bad thing.

Tell that to my mum. She'll think I'm just being silly. Like my dad.

Even on sedatives,

he put off his knee operation for ages.

Then last week, he finally gave in and had the operation here.

We have staff here at the Charité

who know all about this fear.

They even have techniques to get it under control.

If you like, I can book you in for a pre-op appointment.

OK.

Good.

CHARITÉ VILLAGE - BRANDENBURG

And the soil samples?

Nothing either?

What about the... the seeds?

I see. No... No, no. Good,

thank you very much. Goodbye.

So, will I finally get my greenhouse?

Maral?

It looks so beautiful! Yes, er...

Come on, tell me.

Nah, I don't feel like it. I'm done with work.

You look beautiful,

my sweet. You look beautiful.

- Hey. - Michel!

- Hello. - Hey.

Hey! Aww, hello, my darling.

Kiss.

Oh wow! There's nothing quite like Mum's cooking.

See, he's missed us!

Yes, and apparently

wants to move back?

Oh, but only if you have a cosy sofa bed like Grandad's.

Well, you know you can always stay with us.

Thanks Mum.

But for now, I just need a corner where I can put my old things.

Did Nils kick you out?

Hey, I would never do that.

- Hello, you two. - Hello.

It's so nice

to have you back!

- My little daughter. - Let's move over to the table.

Come on, sit down.

I just have to let Dylan know the health department has been in touch.

- On the first evening? - Important case.

Nothing's changed.

Oh come on, you know her.

- Anyone want a drink? - Maral?

I've got another surprise for you. Er...

So you can do something besides work all the time. Here.

Season tickets for the Berliner-Kickers women's team.

Main stand.

Ohhh. Main stand!

But...

aren't these your tickets?

Well, we don't need them anymore.

Right?

Shall we eat first?

We're still waiting for Seda anyway.

So go on... What is it?

I want to join the EIF.

- You're joking, right? - I don't think so.

You taught me to stand up for my values.

That's exactly why I want to fight for our democracy.

So it remains intact for us all, not just for me as a German.

And half Armenian.

But...

their... their missions are incredibly dangerous.

Not if you take part in the Human Performance Enhancement Programme.

- What? - What?

You want to be turned into a "fighting machine"?

Mum!

It's just a nanochip that enhances performance.

A nanochip...

Maral?

Why don't you say something?

I think it's Seda. Let me just open the door.

Terrible idea.

Is that a real pool?

It's Julia's algae saline. Let me take your shoes.

Did you have all those steps built here?

- No, they were already there. - Amazing, so amazing.

Seda!

- Hello Julia! - How lovely.

I'm so glad you're back.

Michel, my big boy.

It's good to see you.

- Seda. - Ah, Nils!

Long time no see.

Oh, how lovely.

Hmm, great atmosphere here.

Wrong subject.

I've brought something for a toast!

Some bubbly!

Getting bougie in your old age?

Well then, let's screw up our scoring!

Here's to the family.

Michel, come help me with the food.

Sure.

I'll join you.

- So... - Yes.

Here you go.

- It's so good. - So my dear.

To the return

of our daughter.

Have you lost weight?

Lost weight? No.

Let me see your hands.

- My hands... - Come on.

What's up with my hands?

When did you last have a check-up?

- Check-up? Give me a break. - Yes.

- Nils. - Oh, that looks amazing!

- Here we go... - All these delicious eats!

High fever. Very invasive ventilation,

advanced sepsis. Shock index over 1.

To the Safadi screening and then the isolation ward!

Julia, Maral, that...

that was fantastic.

Did you like it too?

Oh...

I always find dolmas from the delicatessen

a bit bland.

As bland as my lecture? Or why did you leave

halfway through?

I had a surgery meeting.

Damn tiger mosquitoes.

Have they gotten that bad in Germany?

Oh yes.

I'm just waiting for the next dengue fever wave -

when the insurance

only pays for vaccinations for people

who are really worth it.

Can't we at least sit together at the first dinner we've had in years

without your innuendos?

It's really unbearable.

Your reform is unbearable.

It divides society.

Firstly,

this is not "my" reform!

Secondly, I advised on it, as did dozens of others,

and thirdly...

Incoming call: Dylan Van Boeken.

Dylan?

We have a second case.

What?

Ah, Maral, I'm glad you could get here.

His kidneys and liver are very badly affected.

I've given him the same antibiotic as Mr Baldwin.

It's not working.

No wonder.

Without knowing more about the bacterium, we can't fight it.

Yeah.

If only we knew how and where he contracted it...

And a connection between the two men can definitely be ruled out?

He works as a desaliniser on an offshore island.

He's been out there for the last five weeks.

He couldn't be more isolated.

But there must be some connection between the two.

Good.

First I'll programme an individual antibiotic for Mr Silva as well.

That's all I can do for now.

Stop the reform! Stop the reform! Stop the reform!

WE ARE HUMANS NOT NUMBERS

Stop the reform! Stop the reform!

FIGHT BACK NOW! STOP THIS BLOODY REFORM!

Hey, how are you feeling?

Nervous?

Not with you.

Great.

So we won't need anaesthetic.

Really?

No, of course not.

But the anxiety therapy seems to have helped.

I'm glad.

Let's get started.

Operation authorised.

- OK. - Good.

I will start now.

Attention! Check vital signs.

Hypotension, MAD below 60.

- Dropping. - OK...

Cafedrine and theodrenaline, half vial.

Coming up.

Blood pressure still dropping.

MAD is now below 40.

Heart rate is starting to drop.

Draw up adrenaline. 1 mL. Dilute to 1 in 1000.

It's not working.

MAD continues to fall. Below 20.

- Warning! - Why isn't it working?

- Should I get something? - The AED.

- I'll get the heart pressure robot. - No time.

He's in so much pain!

Can't you do something?

I'll have a look. Good morning, Mrs Baldwin.

Just a second.

His kidneys are damaged.

Right, we'll get him on dialysis

to make him feel better.

Have you asked them if they know the new patient?

Right, er... go right ahead, Maral.

No, we don't know him.

See you later.

Music off.

Come on, Aurelia!

Is there something interacting with the anaesthetic?

Ask her mum.

Call Lore Owanga.

Is Aurelia taking medication

that's not listed in her file?

And drugs?

Check the file again.

She didn't go to anxiety therapy yesterday...

No?

She was totally relaxed.

Yes, maybe she did take a sedative.

But where would she get that from?

Her father. He's also an anxiety patient.

He had a knee operation here. Quickly!

He had calmoren.

Shit. That's gender-sensitive.

SE-11,

two millilitres!

Now!

She's stabilising.

Senior surgeon Seda Safadi.

We're transplanting Felicitas

Abdul-Hai's right kidney today.

Anaesthetist Owen Miles. Erm...

We know that the patient has arteriosclerosis.

No allergies.

Two erythrocyte concentrates combined.

Operating theatre assistant Marlene Hirt.

We're now starting the operation.

- Yes? - Mmhmm.

Operation not authorised.

Try it again.

- Operation not authorised. - Impossible.

The surgical robot is not authorised.

Operation refused.

Wait.

- I think there's a fault here. - No. The operation

has been refused.

- What? - Yes, look.

"No cost coverage by the health insurance.

Surgery cancelled".

This...

this can't be happening.

Oh... really!

Emilia.

I'm about to operate on a patient,

I'm already in the operating room

and the system denies me access

because the insurance company has cancelled the reimbursement.

What a joke!

The patient is under anaesthetic, the organ has already been made.

What's the patient's name?

Abdul-Hai, Felicitas.

It's insane that an operation is cancelled

when the patient is already on the table.

- Because of a sweet! - Wait, my vision is still blurry.

Hold on. Ah, here.

Felicitas Abdul-Hai...

She's diabetic and has refused to cooperate in her recovery,

hasn't changed her diet, cholesterol is consistently high,

doesn't exercise...

Yes,

that's why the kidney won't be covered.

She'll have to continue on dialysis.

She lost her job because she has to go

- for dialysis three times a week. - It's the way it is, Seda.

Nowadays, nobody has to have adult-onset diabetes unless

they refuse to help themselves recover.

But the organ has already been printed!

That is bullshit!

So, Mrs Abdul-Hai is welcome

to pay 250,000 for the transplant, yes?

Then you can go ahead.

Otherwise, the operation will be cancelled, the patient discharged.

Can you do that or shall I do it for you?

Oh, really.

Pfff!

Man!

No way I'm getting rid of you.

Damn.

- We're running out of time! - Your suggestion?

We should bring him

out of his coma and question him for more clues.

With those inflammation levels? His liver and kidneys

are full of microabscesses.

Ventricular fibrillation?

Charged! Clear!

Adrenaline!

Nothing.

Shit!

Charged! Clear!

Charged! Clear!

Shit.

No.

Fuck.

Oh no.

- No. Not now, please. - Oh yes.

Right now!

My patient won't get

a new kidney because of your reform!

I have to send the woman home now -

and I can throw the organ away!

How is that my fault?

You've accepted that the most

socially vulnerable will fall through the cracks.

Do you know how inhumane that is?

A thousand new carers.

Improved care for the majority.

Improved prevention. What's inhumane about that?

It's not about numbers.

It's about people!

Exactly.

And I've just had one die.

I'm so sorry.

I thought... because the remedy

worked so well for Dad against anxiety,

it would work for me too.

Aurelia.

Your father's medication

that you took

is gender-sensitive...

It's safe for men, but not for women.

It causes blood pressure to drop.

That's why it must never be taken before an operation.

You could have died.

You were very lucky.

Report to the anxiety therapist.

And if you can deal with the panic,

then think again very carefully about whether

you want to repeat the operation or not.

OK?

Thank you.

I'm sorry.

I'm sorry.

Greetings, Mrs and Mr Baldwin.

I'm afraid I have some bad news.

Our second patient,

Mr Silva,

has unfortunately passed away.

So...

Piet will also...

Mrs Baldwin, I'll be honest with you. I don't know.

Then...

I'll call our notary now and... Um...

We'll need... um...

the will and the... um...

the advance directive?

Where did you put this

advance directive, Rupert? You rearranged everything

- the other day. - Evi, take it easy.

Everything will be fine.

Everything will be fine.

There must be a connection between Piet and Mr Silva.

Please tell us what you know.

Why would we hide anything? Huh?

Our husband is dying.

Precisely because your husband is dying,

I have to find out how and where he got infected.

Exactly, Maral.

The farm has already been turned upside down.

Exactly.

The off-shore island.

We need to target the off-shore island.

Why the off-shore island?

Mr Silva worked there.

Where exactly?

In Denmark. Hvide Sande.

Is that the connection?

Evelyn?

Piet and I went diving last weekend.

- What? - Mrs Baldwin,

what exactly were you doing there?

We...

we sell seaweed, sometimes fish,

to delicatessens. Under the table.

That's illegal fish trading.

Since when?

Since the drought before last.

We would have lost our farm after the crop failure.

Rupert, we're sorry. We knew you were totally against it.

So why aren't you infected?

Because I stayed in the boat.

- Where exactly? - About...

50 miles north of Norderney.

Thank you, Mrs Baldwin.

That's where it's coming from.

Call Thomas Nguyen.

Ministry of Health.

Directorate-General for Health. Code Red.

I'll put you through immediately.

Maral, what's up?

We have a deadly pathogen in the North Sea.

You must close all beaches immediately.

Maral, the beaches are full!

Get the people out of the water.

Now!

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