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These are the user uploaded subtitles that are being translated: 1 00:00:00,001 --> 00:00:04,291 WILLIAM SHATNER: A trailblazing biologist determined to design 2 00:00:04,292 --> 00:00:06,500 a half-man, half-beast hybrid. 3 00:00:06,667 --> 00:00:09,167 A gifted neuroscientist 4 00:00:09,250 --> 00:00:12,250 whose machine can manipulate the human mind. 5 00:00:12,417 --> 00:00:15,167 And an eccentric aristocrat 6 00:00:15,375 --> 00:00:20,167 who inspired the world's greatest mad scientist. 7 00:00:20,292 --> 00:00:23,583 For thousands of years, mankind's great thinkers 8 00:00:23,750 --> 00:00:27,833 have made enormous contributions to scientific progress. 9 00:00:27,958 --> 00:00:29,578 Yet, throughout the centuries, 10 00:00:29,583 --> 00:00:32,667 there have been more than a few men of science who- 11 00:00:32,875 --> 00:00:35,167 while brilliant in their own right- 12 00:00:35,333 --> 00:00:39,000 pushed the boundaries of experimentation 13 00:00:39,167 --> 00:00:40,583 to the edge of madness. 14 00:00:40,750 --> 00:00:42,750 They were renegades, 15 00:00:42,751 --> 00:00:44,291 known for bizarre experiments 16 00:00:44,292 --> 00:00:47,375 involving human-animal hybrids, 17 00:00:47,542 --> 00:00:49,625 mind control devices, 18 00:00:49,833 --> 00:00:51,792 and even... 19 00:00:51,958 --> 00:00:53,667 unspeakable torture. 20 00:00:53,833 --> 00:00:59,500 What were these mad scientists really trying to achieve? 21 00:00:59,667 --> 00:01:04,708 And what led them down a strange, dark path 22 00:01:04,875 --> 00:01:07,292 in their pursuit of knowledge? 23 00:01:07,458 --> 00:01:11,292 Well, that is what we'll try and find out. 24 00:01:11,458 --> 00:01:13,417 ? ? 25 00:01:28,208 --> 00:01:33,667 A Chinese district court finds biophysicist He Jiankui 26 00:01:33,875 --> 00:01:36,583 guilty of illegal medical practices. 27 00:01:36,750 --> 00:01:41,167 His crime involves a highly controversial procedure 28 00:01:41,333 --> 00:01:45,500 where the DNA of three female embryos is genetically edited 29 00:01:45,708 --> 00:01:49,833 for the purpose of creating HIV-immune babies. 30 00:01:51,208 --> 00:01:53,198 The academic and medical communities 31 00:01:53,208 --> 00:01:57,542 call the radical experiment unsafe and unethical... 32 00:01:57,667 --> 00:02:02,250 and He Jiankui is added to a long list of geniuses 33 00:02:02,417 --> 00:02:05,000 whose dangerous acts have deemed them 34 00:02:05,167 --> 00:02:08,208 "mad scientists." 35 00:02:08,209 --> 00:02:10,374 NINA FARAHANY: I think there are so many questions 36 00:02:10,375 --> 00:02:12,167 about what motivated him. 37 00:02:12,333 --> 00:02:15,163 Scientists are driven by the same kinds of motivations 38 00:02:15,208 --> 00:02:16,768 that other humans are driven by. 39 00:02:16,792 --> 00:02:20,333 In the same way that people want to gain fame or notoriety, 40 00:02:20,500 --> 00:02:23,090 scientists may want to gain fame or notoriety, too. 41 00:02:23,833 --> 00:02:27,125 Sometimes, that ambition drives them to cut corners 42 00:02:27,333 --> 00:02:29,458 or to do unethical experiments 43 00:02:29,625 --> 00:02:32,000 because it could lead to a major breakthrough 44 00:02:32,167 --> 00:02:33,787 that would advance their career. 45 00:02:33,917 --> 00:02:37,417 And that desire to become famous, to get a Nobel Prize, 46 00:02:37,583 --> 00:02:40,125 to be internationally recognized, 47 00:02:40,292 --> 00:02:43,125 can really, in many ways, poison the work 48 00:02:43,292 --> 00:02:44,542 rather than improve it. 49 00:02:44,708 --> 00:02:47,250 ALEX BOESE: There's one particular 50 00:02:47,375 --> 00:02:51,833 psychological bias that scientists are more prone to 51 00:02:52,042 --> 00:02:54,208 than your regular person. 52 00:02:54,375 --> 00:02:58,292 And that's the idea that they can get seduced 53 00:02:58,458 --> 00:03:00,917 by the idea of their own brilliance. 54 00:03:01,083 --> 00:03:05,000 They can get attached to an idea, 55 00:03:05,125 --> 00:03:08,667 and they will go to extraordinary lengths 56 00:03:08,833 --> 00:03:10,667 to be proven right. 57 00:03:10,750 --> 00:03:13,875 The mad scientist represents this idea. 58 00:03:14,042 --> 00:03:15,875 (thunder crashes) 59 00:03:15,876 --> 00:03:17,624 SHATNER: When we think of a mad scientist, 60 00:03:17,625 --> 00:03:19,667 we often imagine an obsessed madman 61 00:03:19,833 --> 00:03:22,792 performing extreme and disturbing experiments 62 00:03:22,958 --> 00:03:24,417 in a dark laboratory... 63 00:03:25,500 --> 00:03:27,875 ...but where does that image come from? 64 00:03:29,000 --> 00:03:32,250 The term "the mad scientist" really enters the mainstream 65 00:03:32,375 --> 00:03:36,292 in 1818 with Mary Shelley's Frankenstein. 66 00:03:37,250 --> 00:03:39,208 Victor Frankenstein was the doctor, 67 00:03:39,375 --> 00:03:42,458 and she described him as a mad scientist, 68 00:03:42,667 --> 00:03:46,250 and that's really the character that we think of 69 00:03:46,417 --> 00:03:48,667 when we think of a mad scientist. 70 00:03:49,708 --> 00:03:53,042 Victor Frankenstein created a humanoid figure. 71 00:03:53,208 --> 00:03:55,292 A monstrous humanoid figure. 72 00:03:55,417 --> 00:03:57,667 He was playing God, 73 00:03:57,833 --> 00:04:00,792 and therefore, he was the ultimate mad scientist. 74 00:04:01,833 --> 00:04:05,625 Mad scientists were fanatically driven to experiment 75 00:04:05,792 --> 00:04:09,000 well away from the eyes of the population, 76 00:04:09,125 --> 00:04:10,958 and often these experiments, 77 00:04:11,125 --> 00:04:13,167 they're unethical, they're immoral. 78 00:04:13,333 --> 00:04:16,083 They could be grotesque and horrifying, 79 00:04:16,250 --> 00:04:18,500 as with Dr. Frankenstein. 80 00:04:18,501 --> 00:04:22,249 WALTER GRUDEN: The stereotype of the mad scientist 81 00:04:22,250 --> 00:04:25,125 comes from the early 19th century. 82 00:04:25,292 --> 00:04:27,458 We know that, at that time, 83 00:04:27,625 --> 00:04:30,292 many scientists worked in isolation, 84 00:04:30,500 --> 00:04:33,000 and so, this idea of a mad scientist, 85 00:04:33,208 --> 00:04:34,458 working by themselves 86 00:04:34,625 --> 00:04:37,583 in some dungeon or laboratory somewhere, 87 00:04:37,750 --> 00:04:41,875 who perpetrated some great crime against humanity, 88 00:04:42,042 --> 00:04:43,583 this comes from 89 00:04:43,708 --> 00:04:48,000 this Victorian-era way of conducting science. 90 00:04:48,001 --> 00:04:50,749 SHATNER: While stories of evil geniuses 91 00:04:50,750 --> 00:04:53,580 have frightened and intrigued us for hundreds of years... 92 00:04:54,542 --> 00:04:58,583 ...in reality, history can point to many gifted scientists 93 00:04:58,792 --> 00:05:00,917 whose work could be called progress... 94 00:05:01,083 --> 00:05:02,667 or perversion. 95 00:05:03,708 --> 00:05:06,375 And perhaps the most surprising example of this 96 00:05:06,542 --> 00:05:10,375 is a brilliant mind from the 17th century 97 00:05:10,542 --> 00:05:13,958 who laid the foundation for modern science... 98 00:05:14,083 --> 00:05:15,583 Sir Isaac Newton. 99 00:05:16,458 --> 00:05:18,583 Isaac Newton was 100 00:05:18,708 --> 00:05:21,542 an extraordinary, extraordinary genius. 101 00:05:21,708 --> 00:05:24,208 He invented 102 00:05:24,375 --> 00:05:27,792 a way of expressing how the world works 103 00:05:27,958 --> 00:05:32,208 in his mammoth book Principia Mathematica, 104 00:05:32,375 --> 00:05:34,917 which was a bestseller in the day. 105 00:05:35,125 --> 00:05:37,542 Basically, he was showing people 106 00:05:37,708 --> 00:05:40,833 how to make sense of the world through mathematical formula. 107 00:05:40,834 --> 00:05:44,541 ROBERT ILIFFE: Newton articulated the three laws of motion. 108 00:05:44,542 --> 00:05:48,000 He devised the principle of universal gravitation. 109 00:05:48,167 --> 00:05:50,083 So, I think it is fair to say 110 00:05:50,208 --> 00:05:52,000 that even his contemporaries 111 00:05:52,167 --> 00:05:55,958 thought that the Principia Mathematica was extraordinary, 112 00:05:56,125 --> 00:05:58,208 and it almost put an end to science. 113 00:05:58,209 --> 00:06:00,041 That is to say, there was very little 114 00:06:00,042 --> 00:06:02,000 left to do after Newton's work. 115 00:06:02,167 --> 00:06:06,125 SHATNER: Yet despite Newton's groundbreaking achievements, 116 00:06:06,333 --> 00:06:09,167 to some, the "Father of Physics" was also 117 00:06:09,375 --> 00:06:12,750 the most famous mad scientist of his time. 118 00:06:12,751 --> 00:06:17,707 JOHN HORGAN: If you're talking about the trope of the mad scientist, 119 00:06:17,708 --> 00:06:23,250 Isaac Newton is a classic example in the sense that, 120 00:06:23,375 --> 00:06:26,042 on the one hand, he is an emblem 121 00:06:26,208 --> 00:06:29,042 of human rationality, 122 00:06:29,208 --> 00:06:30,917 of using human reason 123 00:06:31,083 --> 00:06:32,583 to figure out how nature works. 124 00:06:32,625 --> 00:06:35,667 But Newton was also a crackpot, 125 00:06:35,833 --> 00:06:37,792 we'd have to say, in modern terms. 126 00:06:37,875 --> 00:06:41,042 He was a practitioner in alchemy, 127 00:06:41,208 --> 00:06:45,083 which is this kind of occult precursor of modern chemistry. 128 00:06:45,208 --> 00:06:47,167 He actually did experiments, 129 00:06:47,168 --> 00:06:49,541 hoping he could find the philosopher's stone, 130 00:06:49,542 --> 00:06:52,500 which would be a way to turn lead into gold. 131 00:06:53,667 --> 00:06:56,500 SHATNER: In addition to his interest in alchemy, 132 00:06:56,625 --> 00:06:59,042 Newton's most notable achievements include 133 00:06:59,208 --> 00:07:01,208 the invention of calculus, 134 00:07:01,375 --> 00:07:04,417 the creation of the reflecting telescope, 135 00:07:04,583 --> 00:07:07,083 and groundbreaking work in optics. 136 00:07:08,083 --> 00:07:09,875 But his determination 137 00:07:09,876 --> 00:07:12,499 to understand the composition of light and color- 138 00:07:12,500 --> 00:07:14,875 and how we see them- 139 00:07:15,000 --> 00:07:18,667 would lead him to conduct gruesome experiments... 140 00:07:18,875 --> 00:07:20,792 on his own eyes. 141 00:07:22,583 --> 00:07:25,167 Newton's experiments with his eyeballs 142 00:07:25,375 --> 00:07:27,605 are extraordinary. There's nothing like it. 143 00:07:28,583 --> 00:07:31,458 What he's trying to find out is, how do we see things? 144 00:07:31,459 --> 00:07:33,749 We have two separate notebooks 145 00:07:33,750 --> 00:07:36,000 where he describes in detail what he did, 146 00:07:36,208 --> 00:07:39,167 what the effects were, because they damaged his eyesight. 147 00:07:39,333 --> 00:07:42,833 We know that his eyesight was damaged by looking at the Sun. 148 00:07:43,000 --> 00:07:45,833 So much so that, in the last months of his life, 149 00:07:45,834 --> 00:07:48,957 he recalled that he could still see the Sun if he shut his eyes. 150 00:07:48,958 --> 00:07:50,768 That he'd clearly damaged his eyes 151 00:07:50,833 --> 00:07:53,208 so much that this lasted for 60 years. 152 00:07:54,542 --> 00:07:58,458 RICHARD SPENCE: Newton was really interested in understanding sight. 153 00:07:58,625 --> 00:08:00,375 So, in the pursuit of this, 154 00:08:00,583 --> 00:08:04,875 he took what he called a bodkin, a large needle, 155 00:08:05,042 --> 00:08:07,500 and he decided to see what would happen 156 00:08:07,667 --> 00:08:10,250 if he stuck it into his eye 157 00:08:10,417 --> 00:08:13,583 and pushed it back as far as it would go. 158 00:08:13,584 --> 00:08:16,582 And he saw all these little lights going off, 159 00:08:16,583 --> 00:08:18,208 because if the eye is injured, 160 00:08:18,375 --> 00:08:21,325 it will send little screaming light signals to your brain. 161 00:08:22,583 --> 00:08:25,293 Now, you know, most people probably wouldn't do that. 162 00:08:25,333 --> 00:08:27,750 Isaac Newton was kind of crazy. 163 00:08:27,917 --> 00:08:30,292 IWAN MORUS: On the one hand, 164 00:08:30,417 --> 00:08:32,625 it's perfectly possible to understand 165 00:08:32,792 --> 00:08:35,417 the rationale of what he was doing. 166 00:08:35,583 --> 00:08:38,042 It's a perfectly sensible question: 167 00:08:38,208 --> 00:08:40,618 what does happen to your sight when the eyeball 168 00:08:40,625 --> 00:08:43,042 is distorted in various ways? 169 00:08:43,208 --> 00:08:46,458 But the thought that a good way of answering that question 170 00:08:46,583 --> 00:08:47,958 would be to kind of 171 00:08:48,125 --> 00:08:50,458 push a needle around the back of your eye... 172 00:08:50,625 --> 00:08:55,000 It's just this horrible, horrible thought. 173 00:08:55,208 --> 00:08:58,000 No sane person would do something like that. 174 00:08:58,167 --> 00:09:00,625 But Newton clearly thought that this was 175 00:09:00,792 --> 00:09:03,417 a perfectly sane thing to do. 176 00:09:03,583 --> 00:09:06,250 You know, there lies the mad scientist. 177 00:09:15,208 --> 00:09:17,738 SHATNER: A scruffy-looking dog is found injured 178 00:09:17,750 --> 00:09:20,000 and brought to an animal hospital. 179 00:09:20,208 --> 00:09:23,375 But upon examination, doctors soon realize 180 00:09:23,542 --> 00:09:25,958 this is not a typical canine. 181 00:09:26,875 --> 00:09:28,917 In fact, this four-legged creature 182 00:09:29,042 --> 00:09:32,250 is an entirely new hybrid animal- 183 00:09:32,458 --> 00:09:35,583 a unique combination of domesticated dog 184 00:09:35,708 --> 00:09:38,417 and Pampas fox. 185 00:09:38,583 --> 00:09:41,500 Now identified as a dogxim, 186 00:09:41,708 --> 00:09:44,583 its origins are unknown. 187 00:09:45,542 --> 00:09:47,500 Was it created in nature, 188 00:09:47,667 --> 00:09:51,500 like the coyote-wolf hybrid called coywolves, 189 00:09:51,667 --> 00:09:54,458 or was the dogxim man-made, like the liger, 190 00:09:54,625 --> 00:09:58,125 which is half lion, half tiger? 191 00:09:58,126 --> 00:10:01,291 Our fascination with hybrid creatures 192 00:10:01,292 --> 00:10:04,375 can be traced back for thousands of years, 193 00:10:04,542 --> 00:10:06,532 and many times, these freaks of nature 194 00:10:06,708 --> 00:10:10,333 include strange, unthinkable combinations 195 00:10:10,542 --> 00:10:13,750 that are part animal and part human. 196 00:10:13,875 --> 00:10:18,083 If you go back and look at Paleolithic art, 197 00:10:18,250 --> 00:10:20,500 40,000 years old, 198 00:10:20,708 --> 00:10:23,042 they were painting on cave walls 199 00:10:23,250 --> 00:10:26,125 hybrids of men and birds, 200 00:10:26,250 --> 00:10:28,500 women and bison. 201 00:10:28,708 --> 00:10:32,500 Another famous example is the Sphinx in Egypt. 202 00:10:32,625 --> 00:10:36,667 The body of a lion and the head of a person. 203 00:10:36,875 --> 00:10:40,667 And one of the driving forces behind this was 204 00:10:40,875 --> 00:10:43,458 the idea that it might have been possible, 205 00:10:43,667 --> 00:10:45,375 using magic, 206 00:10:45,583 --> 00:10:47,292 to actually acquire 207 00:10:47,458 --> 00:10:50,083 some of the powers that animals had. 208 00:10:50,250 --> 00:10:51,792 (growling) 209 00:10:51,793 --> 00:10:55,374 SHATNER: While tales of half-man, half-animal creatures 210 00:10:55,375 --> 00:10:59,375 have been part of folklore and mythology since ancient times, 211 00:10:59,542 --> 00:11:01,792 has modern science now reached a point 212 00:11:01,917 --> 00:11:06,000 where human hybrids could become a reality? 213 00:11:07,042 --> 00:11:10,500 This mad notion was the focus of a Russian scientist 214 00:11:10,708 --> 00:11:12,917 with a disturbing vision. 215 00:11:20,625 --> 00:11:22,542 Dictator Joseph Stalin launches 216 00:11:22,750 --> 00:11:25,833 the first Five-Year Plan for the Soviet Union. 217 00:11:26,000 --> 00:11:29,500 Heavy industries like steel, coal and machinery 218 00:11:29,708 --> 00:11:33,042 are the focus of rapid industrialization. 219 00:11:33,208 --> 00:11:36,750 Farmers are pressured to increase their harvests 220 00:11:36,875 --> 00:11:38,875 to support the growing workforce. 221 00:11:39,042 --> 00:11:42,625 And scientists are tasked with figuring out 222 00:11:42,792 --> 00:11:45,792 how to breed stronger livestock. 223 00:11:46,833 --> 00:11:50,625 Leading this effort is a Soviet biologist named... 224 00:11:50,792 --> 00:11:52,583 Ilya Ivanov. 225 00:11:52,750 --> 00:11:55,583 Ilya Ivanov started his career 226 00:11:55,750 --> 00:11:58,917 as a biologist under the czarist regime, 227 00:11:59,083 --> 00:12:02,125 and one of the things that he was very interested in 228 00:12:02,208 --> 00:12:05,333 was the idea of the artificial insemination 229 00:12:05,500 --> 00:12:06,917 of horses and cattle. 230 00:12:07,042 --> 00:12:08,958 So this was a way to take 231 00:12:09,083 --> 00:12:13,167 particular desirable biological traits- 232 00:12:13,292 --> 00:12:15,762 find the stallion who had the traits you wanted, 233 00:12:15,875 --> 00:12:19,250 and if you milked the sperm 234 00:12:19,458 --> 00:12:21,417 and artificially inseminated it, 235 00:12:21,542 --> 00:12:24,750 that one horse can fertilize five thousand mares. 236 00:12:25,792 --> 00:12:28,583 BOESE: Before the 20th century, 237 00:12:28,750 --> 00:12:30,292 artificial insemination was 238 00:12:30,458 --> 00:12:33,333 looked at as something that just would not work. 239 00:12:33,417 --> 00:12:36,958 Ivanov helped to prove that this was not the case. 240 00:12:37,125 --> 00:12:39,833 And he began using these techniques 241 00:12:40,000 --> 00:12:42,792 to create strange new creatures. 242 00:12:42,958 --> 00:12:46,667 He created a zebra-donkey hybrid 243 00:12:46,833 --> 00:12:48,500 called a zedonk 244 00:12:48,708 --> 00:12:51,958 and a bison-cow hybrid called a zubron. 245 00:12:52,083 --> 00:12:54,667 And it was amazingly successful. 246 00:12:54,875 --> 00:12:57,833 He became the foremost expert in the world 247 00:12:57,958 --> 00:12:59,792 on artificial insemination. 248 00:12:59,958 --> 00:13:03,292 But then, he had an even bigger idea. 249 00:13:04,375 --> 00:13:06,917 He thought, could we breed 250 00:13:07,083 --> 00:13:09,167 a human with a chimpanzee? 251 00:13:09,168 --> 00:13:12,124 SHATNER: To most of us, the idea of 252 00:13:12,125 --> 00:13:14,041 a half-human, half-chimpanzee hybrid 253 00:13:14,042 --> 00:13:16,417 sounds, well, insane. 254 00:13:17,583 --> 00:13:19,083 But Ilya Ivanov was convinced 255 00:13:19,250 --> 00:13:21,500 such a combination was possible, 256 00:13:21,501 --> 00:13:23,332 and he became obsessed with the idea 257 00:13:23,333 --> 00:13:27,292 of creating an entirely new species called... 258 00:13:27,458 --> 00:13:29,250 humanzee. 259 00:13:29,251 --> 00:13:31,499 FARAHANY: Ilya Ivanov wanted to create a crossover 260 00:13:31,500 --> 00:13:33,750 between apes and humans. 261 00:13:33,917 --> 00:13:36,542 He called these the "humanzee" experiments. 262 00:13:36,708 --> 00:13:38,708 It was government-funded research. 263 00:13:38,875 --> 00:13:42,292 Part of what people believe he was trying to show 264 00:13:42,458 --> 00:13:45,042 is that humans really did evolve from apes. 265 00:13:45,208 --> 00:13:48,098 And by showing this kind of interspecies impregnation, 266 00:13:48,250 --> 00:13:51,625 it would, in theory, prove that kind of evolutionary link. 267 00:13:51,792 --> 00:13:53,232 As far as we know, Ilya Ivanov 268 00:13:53,233 --> 00:13:54,707 tried this in a lot of different ways. 269 00:13:54,708 --> 00:13:58,250 He tried to get human women 270 00:13:58,375 --> 00:14:03,500 to be willing to be inseminated artificially by ape sperm. 271 00:14:03,667 --> 00:14:05,792 He tried to transplant tissue 272 00:14:05,958 --> 00:14:08,500 from the uterus of a human woman 273 00:14:08,708 --> 00:14:11,000 into an ape. 274 00:14:11,125 --> 00:14:14,250 He was willing to do it in any way that was possible. 275 00:14:14,417 --> 00:14:17,208 BOESE: For one of his experiments, 276 00:14:17,375 --> 00:14:19,250 in the summer of 1927, 277 00:14:19,458 --> 00:14:22,167 Ivanov managed to bring back to the Soviet Union 278 00:14:22,333 --> 00:14:24,292 a male orangutan. 279 00:14:24,500 --> 00:14:26,000 He named him Tarzan. 280 00:14:26,167 --> 00:14:28,167 And he actually managed to find 281 00:14:28,375 --> 00:14:32,000 five female volunteers in the Soviet Union. 282 00:14:32,208 --> 00:14:37,042 One of the women memorably commented that 283 00:14:37,208 --> 00:14:39,018 "I'm willing to volunteer for this 284 00:14:39,167 --> 00:14:44,375 because I feel that my life has no more sense anymore." 285 00:14:44,542 --> 00:14:50,167 So, I think he was somehow tapping into the suicidal women 286 00:14:50,375 --> 00:14:55,083 in the Soviet Union who were just gonna abandon all hope 287 00:14:55,250 --> 00:14:58,417 to participate in this gruesome experiment. 288 00:14:58,542 --> 00:15:01,958 But Ivanov had failed in his attempt, 289 00:15:02,125 --> 00:15:06,042 because the orangutan promptly died. 290 00:15:07,042 --> 00:15:09,333 Soon after that, one of his colleagues 291 00:15:09,500 --> 00:15:12,958 reported him for counterrevolutionary activities 292 00:15:13,083 --> 00:15:15,917 and he got arrested in one of Stalin's purges. 293 00:15:16,125 --> 00:15:19,833 They exiled him to Kazakhstan. 294 00:15:20,042 --> 00:15:22,375 Two years later, he died of a stroke. 295 00:15:22,542 --> 00:15:25,458 That was the end of his research project. 296 00:15:25,625 --> 00:15:30,958 SHATNER: Was Ilya Ivanov's dedication to his delusional hybrid project 297 00:15:31,083 --> 00:15:35,583 simply to prove that human beings had evolved from apes... 298 00:15:35,584 --> 00:15:38,541 ...or was there a more diabolical plan 299 00:15:38,542 --> 00:15:43,667 driving the 10-year odyssey to create a humanzee? 300 00:15:43,833 --> 00:15:47,458 Why would a Soviet scientist want to create a humanzee? 301 00:15:48,750 --> 00:15:52,458 Well, we don't really know, but we can take some guesses. 302 00:15:52,625 --> 00:15:55,500 One of those would be that he was trying to 303 00:15:55,667 --> 00:15:56,958 create a super soldier. 304 00:15:57,167 --> 00:15:59,167 When you talk about a chimpanzee, 305 00:15:59,168 --> 00:16:01,291 you're talking about more stamina, more strength. 306 00:16:01,292 --> 00:16:04,500 If you can pull some of those traits into a soldier, 307 00:16:04,708 --> 00:16:07,778 you would have, essentially, a real-life Captain America, 308 00:16:07,792 --> 00:16:12,083 and if you ask me, it's probably what Ivanov was trying to do. 309 00:16:12,084 --> 00:16:15,041 SHATNER: While it's widely believed 310 00:16:15,042 --> 00:16:18,333 that Ivanov's controversial experiments failed... 311 00:16:18,542 --> 00:16:20,333 his work still raises 312 00:16:20,542 --> 00:16:22,792 some very important ethical questions. 313 00:16:23,833 --> 00:16:28,083 Even if Ivanov could create an ape-man in a laboratory, 314 00:16:28,208 --> 00:16:30,500 should he have ever been allowed 315 00:16:30,625 --> 00:16:33,417 to try in the first place? 316 00:16:33,583 --> 00:16:38,083 The humanzee experiments raise so many ethical concerns. 317 00:16:38,250 --> 00:16:41,750 Ilya Ivanov really regarded, 318 00:16:41,917 --> 00:16:44,333 you know, whether it was humans or apes, 319 00:16:44,500 --> 00:16:48,083 not as, you know, beings that required 320 00:16:48,250 --> 00:16:49,667 and demanded our respect, 321 00:16:49,875 --> 00:16:52,167 but really as instruments 322 00:16:52,333 --> 00:16:54,667 for his different scientific experiments. 323 00:16:54,875 --> 00:16:57,167 So, imagine for a moment 324 00:16:57,292 --> 00:17:00,250 that the humanzee experiments had actually succeeded. 325 00:17:00,251 --> 00:17:02,291 We have no idea what the consequences 326 00:17:02,292 --> 00:17:04,041 for the woman would have been. Would it have 327 00:17:04,042 --> 00:17:05,667 destroyed her health? 328 00:17:05,833 --> 00:17:07,833 And how would we regard that species? 329 00:17:08,042 --> 00:17:09,542 Would we think that was a human 330 00:17:09,583 --> 00:17:11,708 that had all of the same rights as a human? 331 00:17:11,875 --> 00:17:13,958 It's almost impossible 332 00:17:13,959 --> 00:17:16,332 to grapple with the full set of implications 333 00:17:16,333 --> 00:17:18,875 of an experiment like that. 334 00:17:19,042 --> 00:17:21,583 Why, for thousands of years, 335 00:17:21,750 --> 00:17:23,708 have humans been so obsessed 336 00:17:23,875 --> 00:17:25,667 with creating hybrid creatures? 337 00:17:25,833 --> 00:17:29,167 One thing that many mad scientists have in common 338 00:17:29,333 --> 00:17:31,333 is that they rarely consider 339 00:17:31,542 --> 00:17:34,125 the consequences of their experiments. 340 00:17:34,292 --> 00:17:38,542 Which was the case with the Harvard professor 341 00:17:38,750 --> 00:17:40,500 whose research into mind control 342 00:17:40,708 --> 00:17:42,875 may have turned one of his students 343 00:17:43,042 --> 00:17:45,583 into a dangerous madman. 344 00:17:51,542 --> 00:17:54,167 SHATNER: Since its founding in 1636, 345 00:17:54,375 --> 00:17:57,500 some of the brightest minds in science 346 00:17:57,708 --> 00:18:00,583 have taught at this esteemed institution... 347 00:18:01,625 --> 00:18:05,500 ...including James Watson, a pioneer in the science of DNA, 348 00:18:05,667 --> 00:18:09,208 Nobel-Prize-winning physicist Sheldon Glashow, 349 00:18:09,375 --> 00:18:12,042 and the highly controversial psychologist 350 00:18:12,208 --> 00:18:15,500 named Dr. Henry Murray. 351 00:18:16,458 --> 00:18:19,250 GENTILE: Henry Murray was a psychologist 352 00:18:19,417 --> 00:18:22,083 who, during World War II, worked for the OSS. 353 00:18:22,208 --> 00:18:24,042 The OSS is the precursor to the CIA. 354 00:18:24,208 --> 00:18:26,000 So this is military intelligence. 355 00:18:26,125 --> 00:18:28,055 And what he was trying to find out was, 356 00:18:28,208 --> 00:18:30,792 how far can you push a man before he breaks? 357 00:18:30,958 --> 00:18:33,458 He was testing the limits of soldiers 358 00:18:33,583 --> 00:18:35,875 put under interrogation and pressure. 359 00:18:36,042 --> 00:18:38,167 After the war, 360 00:18:38,292 --> 00:18:41,500 Murray went to work at Harvard as a psychologist. 361 00:18:41,625 --> 00:18:44,000 COBB: During his time at Harvard, 362 00:18:44,208 --> 00:18:46,958 Henry Murray was very interested 363 00:18:47,167 --> 00:18:50,125 in how people respond under extreme stress, 364 00:18:50,292 --> 00:18:52,333 how personality is shaped and changes. 365 00:18:52,458 --> 00:18:55,542 He was committed to do so at any cost. 366 00:18:55,750 --> 00:18:57,833 And if that meant subjecting students 367 00:18:58,000 --> 00:18:59,320 to extreme stress to do it, 368 00:18:59,321 --> 00:19:01,374 then Henry Murray was, was okay with that. 369 00:19:01,375 --> 00:19:03,333 SHATNER: At Harvard, 370 00:19:03,500 --> 00:19:05,370 Murray began a new research project 371 00:19:05,458 --> 00:19:08,375 titled "Multiform Assessments 372 00:19:08,542 --> 00:19:11,917 of Personality Development Among Gifted College Men." 373 00:19:12,083 --> 00:19:14,000 He would experiment 374 00:19:14,208 --> 00:19:16,438 with intelligent Harvard undergraduates 375 00:19:16,583 --> 00:19:19,833 to observe how they responded to extreme 376 00:19:20,000 --> 00:19:22,750 psychological stress. 377 00:19:22,751 --> 00:19:24,541 GENTILE: He wasn't looking for 378 00:19:24,542 --> 00:19:27,958 students that had a sense of self-confidence. 379 00:19:28,167 --> 00:19:31,000 He wanted students that were 380 00:19:31,208 --> 00:19:33,208 feeling isolated, out of place, 381 00:19:33,375 --> 00:19:37,167 having trouble acclimating to college. 382 00:19:38,500 --> 00:19:41,792 He wanted weak people to be part of this experiment 383 00:19:41,917 --> 00:19:43,000 not strong ones, 384 00:19:43,167 --> 00:19:45,250 because the weak mind 385 00:19:45,417 --> 00:19:47,542 is just much easier to break. 386 00:19:47,708 --> 00:19:50,500 So, he conducted very in-depth interviews 387 00:19:50,501 --> 00:19:53,499 with these students that were potentially for the study. 388 00:19:53,500 --> 00:19:55,667 He wanted to know what their values were, 389 00:19:55,792 --> 00:19:58,083 what their fears were, what they believed, 390 00:19:58,084 --> 00:20:00,166 what made them proud, what made them nervous, 391 00:20:00,167 --> 00:20:01,917 what made them ashamed. 392 00:20:02,083 --> 00:20:04,750 And, from there, selected 22 students 393 00:20:04,875 --> 00:20:06,333 to be part of the program. 394 00:20:06,458 --> 00:20:09,375 SHATNER: From 1941 to 1962, 395 00:20:09,542 --> 00:20:13,208 Dr. Murray engaged five groups of 22 men. 396 00:20:13,375 --> 00:20:17,167 Each group committed to 200 hours of intensive testing 397 00:20:17,333 --> 00:20:19,792 from their sophomore to senior years. 398 00:20:19,793 --> 00:20:21,499 After collecting information 399 00:20:21,500 --> 00:20:23,957 about each subject's life, beliefs and values, 400 00:20:23,958 --> 00:20:25,500 they were confronted with 401 00:20:25,708 --> 00:20:29,167 "vehement, sweeping and personally abusive attacks," 402 00:20:29,292 --> 00:20:31,167 all intended to trigger 403 00:20:31,333 --> 00:20:34,583 crippling levels of stress and mental collapse. 404 00:20:35,708 --> 00:20:37,518 TONY McMAHON: He was using tactics 405 00:20:37,583 --> 00:20:40,833 that he'd learnt working in the intelligence services 406 00:20:40,917 --> 00:20:43,167 during the Second World War. 407 00:20:43,375 --> 00:20:47,000 Murray's methodology was to, first of all, 408 00:20:47,208 --> 00:20:50,167 have a brightly lit room in which he'd create 409 00:20:50,333 --> 00:20:52,917 what were termed "confrontational scenarios." 410 00:20:53,750 --> 00:20:57,167 So, his subjects would be covered in electrodes 411 00:20:57,333 --> 00:21:00,958 and then basically shouted at, yelled at, 412 00:21:01,083 --> 00:21:02,833 and this was hugely distressing. 413 00:21:02,958 --> 00:21:06,333 COBB: In essence, Murray would spend many sessions 414 00:21:06,500 --> 00:21:08,125 just berating students, 415 00:21:08,250 --> 00:21:09,833 and they would use those things 416 00:21:09,958 --> 00:21:11,958 that were dear to those students 417 00:21:12,083 --> 00:21:14,292 to deflate their self-esteem. 418 00:21:14,417 --> 00:21:16,958 To make them feel like they were worthless. 419 00:21:17,125 --> 00:21:19,125 To give them a sense that, 420 00:21:19,250 --> 00:21:20,833 the things that they believe, 421 00:21:20,917 --> 00:21:22,500 the things that define them, 422 00:21:22,625 --> 00:21:24,042 were horrible things. 423 00:21:24,208 --> 00:21:27,292 Even Murray, by his own admission, said 424 00:21:27,417 --> 00:21:30,458 that these were vehement assaults on the ego 425 00:21:30,625 --> 00:21:33,155 with the intention of breaking individuals down. 426 00:21:33,156 --> 00:21:35,749 There was some controversy 427 00:21:35,750 --> 00:21:38,625 and some dissentment among his colleagues 428 00:21:38,792 --> 00:21:40,708 that he was a fringe psychologist. 429 00:21:40,875 --> 00:21:43,583 And when one considers lonely undergrads 430 00:21:43,584 --> 00:21:45,874 and the developmental period in which they're in, 431 00:21:45,875 --> 00:21:48,208 that kind of treatment, 432 00:21:48,375 --> 00:21:50,125 that kind of torture, 433 00:21:50,208 --> 00:21:52,000 it stays with the person. 434 00:21:52,083 --> 00:21:55,667 The students of Murray's experiments, 25 years later, 435 00:21:55,833 --> 00:21:58,250 noted serious negative side effects 436 00:21:58,417 --> 00:22:01,458 of both physical health, mental health, social health 437 00:22:01,625 --> 00:22:02,833 that remained with them. 438 00:22:02,958 --> 00:22:04,208 (yelling) 439 00:22:04,209 --> 00:22:05,874 SHATNER: What motivated Dr. Murray 440 00:22:05,875 --> 00:22:09,000 to conduct such disturbing and cruel experiments 441 00:22:09,208 --> 00:22:10,875 on vulnerable young minds? 442 00:22:11,875 --> 00:22:14,208 Was it a radical act in the name of science, 443 00:22:14,375 --> 00:22:15,695 or was there a bigger force 444 00:22:15,833 --> 00:22:19,958 influencing the psychologist's mad project? 445 00:22:21,208 --> 00:22:23,167 While it's a matter of debate, 446 00:22:23,168 --> 00:22:25,291 some believe Henry Murray may have been 447 00:22:25,292 --> 00:22:27,167 working for the U.S. government's 448 00:22:27,250 --> 00:22:30,042 Central Intelligence Agency. 449 00:22:30,208 --> 00:22:32,138 There are rumors that he was, in fact, 450 00:22:32,208 --> 00:22:34,667 still working for the CIA, 451 00:22:34,833 --> 00:22:37,542 trying to develop techniques of mind control. 452 00:22:37,708 --> 00:22:41,167 I mean, when asked, Murray was quite cagey 453 00:22:41,375 --> 00:22:44,292 about, you know, just what he was trying to do. 454 00:22:44,458 --> 00:22:45,958 Though I do sometimes wonder, 455 00:22:46,083 --> 00:22:48,833 was Murray really capable of 456 00:22:49,000 --> 00:22:52,042 controlling the way other people thought 457 00:22:52,250 --> 00:22:53,917 as a result of his experiments? 458 00:22:53,918 --> 00:22:58,541 SHATNER: Is it possible that Murray's diabolical Harvard experiment 459 00:22:58,542 --> 00:23:02,000 was secretly a mind control program for the CIA? 460 00:23:02,208 --> 00:23:04,125 We can only speculate. 461 00:23:04,292 --> 00:23:05,583 But what we do know 462 00:23:05,792 --> 00:23:08,083 is that one of Murray's test subjects 463 00:23:08,250 --> 00:23:10,042 died in a supermax prison 464 00:23:10,208 --> 00:23:14,542 for a crime spree that caused death and destruction 465 00:23:14,708 --> 00:23:16,917 across the United States. 466 00:23:17,042 --> 00:23:20,083 His name was Ted Kaczynski, 467 00:23:20,208 --> 00:23:23,833 also known as The Unabomber. 468 00:23:23,958 --> 00:23:26,875 Ted Kaczynski was only 16 years old when he was at Harvard. 469 00:23:27,042 --> 00:23:28,375 This is a very, 470 00:23:28,376 --> 00:23:29,791 very impressionable developmental period 471 00:23:29,792 --> 00:23:31,292 and one can't help but think, 472 00:23:31,417 --> 00:23:33,167 what exactly was the role 473 00:23:33,375 --> 00:23:35,500 of Murray's experiments 474 00:23:35,583 --> 00:23:38,125 on Ted Kaczynski's future behavior? 475 00:23:39,125 --> 00:23:42,167 The Unabomber carried out a series of bombings 476 00:23:42,375 --> 00:23:44,250 in which three people were killed 477 00:23:44,375 --> 00:23:46,542 and 23 injured. 478 00:23:46,543 --> 00:23:49,124 And, of course, people have wondered 479 00:23:49,125 --> 00:23:52,333 was it as a result of Murray's experiments 480 00:23:52,542 --> 00:23:55,000 that Kaczynski went on to become 481 00:23:55,208 --> 00:23:58,167 this sociopathic serial killer? 482 00:23:58,375 --> 00:24:00,917 We know that for a fact from his manifesto, 483 00:24:01,083 --> 00:24:05,083 where Kaczynski specifically went after 484 00:24:05,208 --> 00:24:07,833 the American scientific community 485 00:24:08,000 --> 00:24:10,917 and he attacked psychology as a field. 486 00:24:11,083 --> 00:24:15,167 Now, we can't make a direct, exact correlation that, 487 00:24:15,375 --> 00:24:18,000 did this experiment in mind control 488 00:24:18,208 --> 00:24:20,333 cause Ted Kaczynski 489 00:24:20,458 --> 00:24:22,928 to become, essentially, a domestic terrorist? 490 00:24:22,929 --> 00:24:23,916 We can't do that. 491 00:24:23,917 --> 00:24:27,208 But certainly these experiments 492 00:24:27,375 --> 00:24:29,708 built Kaczynski's worldview. 493 00:24:30,792 --> 00:24:33,792 The psychological mind control experiments 494 00:24:33,958 --> 00:24:37,292 conducted by Dr. Murray are distressing, 495 00:24:37,458 --> 00:24:38,792 to say the least. 496 00:24:38,958 --> 00:24:41,875 But there's another mad scientist 497 00:24:42,042 --> 00:24:44,833 whose fascination with electric medicine 498 00:24:44,958 --> 00:24:48,375 led to the creation of manipulative- 499 00:24:48,542 --> 00:24:50,708 and shocking- 500 00:24:50,875 --> 00:24:52,583 experiments. 501 00:25:01,708 --> 00:25:04,833 SHATNER: Cardiologist Dr. Claude S. Beck 502 00:25:05,042 --> 00:25:07,917 is performing open heart surgery... 503 00:25:08,917 --> 00:25:11,875 ...when his patient suddenly goes into cardiac arrest. 504 00:25:12,042 --> 00:25:15,250 In that moment, Beck decides to use 505 00:25:15,417 --> 00:25:18,083 an untested invention of his own design 506 00:25:18,250 --> 00:25:21,833 and saves his patient's life by shocking him 507 00:25:22,000 --> 00:25:24,667 with 1500 volts of electricity. 508 00:25:26,917 --> 00:25:29,667 Dr. Beck's invention, called a defibrillator... 509 00:25:31,542 --> 00:25:35,083 ...and other devices, like the pacemaker 510 00:25:35,292 --> 00:25:37,083 and the cochlear implant, 511 00:25:37,292 --> 00:25:41,417 has transformed lives through electric medicine. 512 00:25:41,583 --> 00:25:43,583 But while it's easy to see the benefits 513 00:25:43,750 --> 00:25:46,667 electricity has offered medical advancement, 514 00:25:46,875 --> 00:25:49,625 it is not without controversy. 515 00:25:51,750 --> 00:25:54,667 Such is the case surrounding a troubling tool 516 00:25:54,875 --> 00:25:57,000 invented by a brilliant brain scientist 517 00:25:57,208 --> 00:25:59,542 named Jos� Delgado. 518 00:26:01,083 --> 00:26:02,833 Jos� Delgado, I'd say, 519 00:26:03,042 --> 00:26:06,833 is the most flamboyant, outrageous, 520 00:26:06,958 --> 00:26:11,208 fascinating scientist I've ever interviewed personally. 521 00:26:12,417 --> 00:26:15,083 He moved to Yale in 1950. 522 00:26:15,208 --> 00:26:16,500 And while he was there, 523 00:26:16,501 --> 00:26:18,332 over the next two and a half decades, 524 00:26:18,333 --> 00:26:21,583 he did all these experiments involving brain implants. 525 00:26:22,792 --> 00:26:24,625 And he spelled this out in a book 526 00:26:24,750 --> 00:26:27,958 that was published in 1969 527 00:26:28,125 --> 00:26:31,333 called Physical Control of the Mind. 528 00:26:31,334 --> 00:26:34,166 For example, he developed something 529 00:26:34,167 --> 00:26:35,625 called the stimoceiver, 530 00:26:35,750 --> 00:26:39,875 which is a device about the size of a half dollar 531 00:26:40,042 --> 00:26:42,167 that could be inserted inside the skull, 532 00:26:42,292 --> 00:26:44,667 and had electrodes inserted into the brain 533 00:26:44,833 --> 00:26:46,917 that could both detect signals 534 00:26:46,918 --> 00:26:49,541 being passed from one part of the brain to another 535 00:26:49,542 --> 00:26:51,167 and also stimulate the brain 536 00:26:51,292 --> 00:26:53,167 to get various effects. 537 00:26:54,167 --> 00:26:58,292 Through this period, Delgado did a lot of experiments on monkeys. 538 00:26:58,500 --> 00:27:01,042 He had all these monkeys in a chamber, 539 00:27:01,250 --> 00:27:05,292 and there was one big alpha male bully and... 540 00:27:05,458 --> 00:27:07,208 and a bunch of females. 541 00:27:07,375 --> 00:27:09,333 Delgado put a stimoceiver 542 00:27:09,458 --> 00:27:11,500 in the brain of the male monkey, 543 00:27:11,583 --> 00:27:13,417 and when he pushed the lever, 544 00:27:13,542 --> 00:27:15,375 it would pacify the male 545 00:27:15,376 --> 00:27:17,207 and the male would suddenly become 546 00:27:17,208 --> 00:27:19,078 meek and mild and cower in the corner. 547 00:27:19,083 --> 00:27:21,667 There was a little bit of this 548 00:27:21,875 --> 00:27:25,708 kind of mad scientist aspect of him. 549 00:27:25,875 --> 00:27:27,583 Through this period also, 550 00:27:27,750 --> 00:27:29,458 Delgado had been experimenting 551 00:27:29,667 --> 00:27:33,167 not only on animals but also on humans. 552 00:27:35,292 --> 00:27:37,750 So, in the 1950s, he was going 553 00:27:37,875 --> 00:27:39,792 into mental hospitals 554 00:27:39,875 --> 00:27:44,167 and inserting brain implants into mental patients, 555 00:27:44,333 --> 00:27:47,167 most of whom had epilepsy or schizophrenia. 556 00:27:47,333 --> 00:27:50,708 He's trying to show the power of these technologies 557 00:27:50,875 --> 00:27:53,583 for treating severe mental illness, 558 00:27:53,750 --> 00:27:57,750 In his book Physical Control of the Mind, 559 00:27:57,958 --> 00:28:01,250 he was showing that he could control people's emotions. 560 00:28:01,417 --> 00:28:02,792 He could make them laugh, 561 00:28:02,917 --> 00:28:05,292 he could make them feel rage, 562 00:28:05,417 --> 00:28:08,500 just by pressing a button 563 00:28:08,708 --> 00:28:12,292 which was controlling the, uh, the stimoceivers 564 00:28:12,458 --> 00:28:14,542 implanted in their brains. 565 00:28:14,543 --> 00:28:16,457 He wanted to take the technology as- 566 00:28:16,458 --> 00:28:19,125 as far as it could possibly go. 567 00:28:19,126 --> 00:28:23,666 SHATNER: Delgado claimed that his radical experiments with the stimoceiver 568 00:28:23,667 --> 00:28:26,875 showed evidence that human behavior could be manipulated 569 00:28:27,042 --> 00:28:30,250 by applying electricity to the brain. 570 00:28:32,167 --> 00:28:35,458 And to prove it, Delgado created a public demonstration 571 00:28:35,625 --> 00:28:37,833 of his mind control machine 572 00:28:38,042 --> 00:28:40,125 after embedding his device 573 00:28:40,292 --> 00:28:42,792 in the brain of a bull. 574 00:28:42,917 --> 00:28:48,167 Delgado famously went into a ring with a bull. 575 00:28:48,333 --> 00:28:50,792 And the only thing he was holding in his hand 576 00:28:50,958 --> 00:28:53,500 was a radio receiver. 577 00:28:53,708 --> 00:28:56,500 And as the bull charged toward him, 578 00:28:56,667 --> 00:28:57,917 he pressed a button 579 00:28:58,083 --> 00:29:00,000 and the bull suddenly stopped. 580 00:29:00,125 --> 00:29:02,500 And what he was trying to show 581 00:29:02,708 --> 00:29:05,542 was that it was possible to control behavior 582 00:29:05,708 --> 00:29:07,833 of other species through electrodes. 583 00:29:08,000 --> 00:29:10,625 But what it also did was show people 584 00:29:10,708 --> 00:29:14,000 how powerfully the brain can be manipulated 585 00:29:14,167 --> 00:29:17,000 and induce fear in the public 586 00:29:17,167 --> 00:29:19,708 about the possibility of brain control 587 00:29:19,917 --> 00:29:21,297 and external brain control 588 00:29:21,375 --> 00:29:24,875 by what could be seen as a mad scientist. 589 00:29:25,042 --> 00:29:27,333 The problem with his technology is 590 00:29:27,458 --> 00:29:30,542 it isn't designed to suddenly change somebody 591 00:29:30,750 --> 00:29:33,000 from charging at you to stop charging at you. 592 00:29:33,125 --> 00:29:35,355 It's designed to suddenly change behavior 593 00:29:35,458 --> 00:29:39,167 and to make people or species into puppets. 594 00:29:40,625 --> 00:29:42,292 HORGAN: Delgado had a vision 595 00:29:42,500 --> 00:29:45,833 for humanity being reshaped 596 00:29:45,917 --> 00:29:48,458 by these technologies that he was developing. 597 00:29:49,708 --> 00:29:52,500 In his book Physical Control of the Mind, 598 00:29:52,625 --> 00:29:56,333 he said that technologies like the one he was developing 599 00:29:56,417 --> 00:30:00,792 had the capacity to transform human society for the better, 600 00:30:01,000 --> 00:30:03,333 to create this kind of utopia, 601 00:30:03,417 --> 00:30:07,083 but he's describing his patients as though they are puppets. 602 00:30:08,083 --> 00:30:10,333 He can make their limbs move up and down. 603 00:30:10,458 --> 00:30:14,542 He can make them wave their arms and clench their fists. 604 00:30:14,750 --> 00:30:17,667 He can make them laugh on command. 605 00:30:17,833 --> 00:30:20,625 And what-what's creepy is that 606 00:30:20,792 --> 00:30:22,833 often these people thought they were 607 00:30:23,000 --> 00:30:25,500 doing these things of their own free will. 608 00:30:25,501 --> 00:30:28,457 SPENCE: Where does it cross the line 609 00:30:28,458 --> 00:30:31,667 between understanding how the brain works 610 00:30:31,792 --> 00:30:36,292 and then making it work in a particular way? 611 00:30:36,458 --> 00:30:39,583 So, if we could just have a remote control, 612 00:30:39,750 --> 00:30:44,000 and press a button and make them behave in certain ways, 613 00:30:44,167 --> 00:30:46,792 the next question becomes, why not? 614 00:30:47,000 --> 00:30:51,708 BOESE: If we think of what Delgado was doing 615 00:30:51,875 --> 00:30:56,667 to control human movement and behavior, 616 00:30:56,875 --> 00:31:00,000 then that raises the question of 617 00:31:00,208 --> 00:31:03,458 who gets to play God, in that sense? 618 00:31:03,625 --> 00:31:07,667 Who-who, then, gets to control that behavior? 619 00:31:07,833 --> 00:31:10,083 If we are like puppets, 620 00:31:10,292 --> 00:31:12,542 then who is pulling the strings? 621 00:31:15,875 --> 00:31:18,417 The idea of creating an army of human puppets 622 00:31:18,542 --> 00:31:20,500 is certainly unnerving. 623 00:31:20,708 --> 00:31:25,833 But when it comes to conducting diabolical human experiments, 624 00:31:26,042 --> 00:31:27,782 the medical atrocities committed 625 00:31:27,958 --> 00:31:31,500 during World War II stand alone, 626 00:31:31,667 --> 00:31:35,333 and earned one mad scientist 627 00:31:35,542 --> 00:31:37,292 the terrifying nickname... 628 00:31:37,458 --> 00:31:40,000 "the Angel of Death." 629 00:31:44,500 --> 00:31:48,000 SHATNER: The Auschwitz-Birkenau state museum, Poland. 630 00:31:50,250 --> 00:31:52,083 During World War II, it was the site 631 00:31:52,292 --> 00:31:55,292 of some of the worst atrocities in all of human history. 632 00:31:55,293 --> 00:31:58,332 Over one million innocent victims 633 00:31:58,333 --> 00:32:00,417 were murdered here by the Nazis. 634 00:32:01,333 --> 00:32:03,083 And later, survivors would speak 635 00:32:03,250 --> 00:32:05,833 of a sadistic doctor stationed here, 636 00:32:06,042 --> 00:32:09,625 responsible for truly horrific experiments 637 00:32:09,833 --> 00:32:11,708 on the prisoners, 638 00:32:11,875 --> 00:32:14,208 named Dr. Josef Mengele. 639 00:32:15,500 --> 00:32:17,917 MORUS: There's no more notorious example 640 00:32:18,083 --> 00:32:21,167 of the extremes of scientific experimentation 641 00:32:21,375 --> 00:32:24,958 than Josef Mengele at Auschwitz 642 00:32:25,042 --> 00:32:27,152 during the course of the Second World War. 643 00:32:28,208 --> 00:32:32,000 His victims called Mengele "The Angel of Death." 644 00:32:32,167 --> 00:32:34,817 When he came around, they knew they were going to die 645 00:32:34,958 --> 00:32:38,583 in horrible, vicious ways. 646 00:32:40,083 --> 00:32:42,375 SPENCE: Mengele joins the Nazi party in '37. 647 00:32:42,500 --> 00:32:46,083 Early on, he's actually a combat doctor. 648 00:32:46,208 --> 00:32:48,292 He's wounded on the Russian front, 649 00:32:48,417 --> 00:32:50,500 sent back to Germany to recover, 650 00:32:50,708 --> 00:32:54,000 and then reassigned as the chief medical officer 651 00:32:54,167 --> 00:32:58,000 of this prison industrial extermination complex 652 00:32:58,167 --> 00:33:02,542 with an almost unlimited supply of test subjects, 653 00:33:02,750 --> 00:33:04,417 and given relatively free reign 654 00:33:04,583 --> 00:33:07,173 to conduct whatever research it was that he wanted. 655 00:33:07,292 --> 00:33:09,875 That consisted of things like 656 00:33:09,876 --> 00:33:11,707 removing a kidney from a prisoner 657 00:33:11,708 --> 00:33:14,082 and then putting them back in their work detail 658 00:33:14,083 --> 00:33:16,673 to see whether or not they could continue to do that. 659 00:33:16,792 --> 00:33:21,458 He deliberately infected prisoners with various diseases. 660 00:33:21,625 --> 00:33:24,458 But he was very interested in genetics. 661 00:33:24,625 --> 00:33:26,542 One of his favorite things 662 00:33:26,708 --> 00:33:28,958 was to work with children, 663 00:33:29,125 --> 00:33:31,083 particularly sets of twins. 664 00:33:31,208 --> 00:33:33,000 And he would take the twins 665 00:33:33,208 --> 00:33:35,625 and use one as the experiment 666 00:33:35,792 --> 00:33:38,042 and the other as a control. 667 00:33:38,208 --> 00:33:41,250 What is so inexplicable about Mengele 668 00:33:41,375 --> 00:33:44,875 is he could be so kind and warm and gentle 669 00:33:45,042 --> 00:33:46,708 to these children one day, 670 00:33:46,709 --> 00:33:48,874 giving them chocolates, giving them candy, 671 00:33:48,875 --> 00:33:52,792 and the next day, turn around and torture and murder them. 672 00:33:52,958 --> 00:33:55,250 What kind of monster does it take 673 00:33:55,417 --> 00:33:57,042 to do something like that? 674 00:33:57,208 --> 00:34:00,292 SHATNER: What madness causes a man of science 675 00:34:00,417 --> 00:34:02,583 to become a sadistic monster? 676 00:34:02,584 --> 00:34:05,541 Some believe the answer may be found 677 00:34:05,542 --> 00:34:09,042 by examining a secret Japanese program during World War II. 678 00:34:13,708 --> 00:34:16,250 Tucked away in this city of ten million people, 679 00:34:16,375 --> 00:34:19,458 a group of brick buildings stand as a grim memorial. 680 00:34:20,708 --> 00:34:23,250 It is the home of a research and development unit 681 00:34:23,417 --> 00:34:26,708 created by the Japanese during their occupation of China 682 00:34:26,875 --> 00:34:29,208 in the 1930s and 1940s. 683 00:34:29,375 --> 00:34:32,458 And it is the place where thousands of prisoners 684 00:34:32,625 --> 00:34:35,000 were the victims of heinous experiments 685 00:34:35,167 --> 00:34:36,833 conducted under the direction 686 00:34:36,917 --> 00:34:40,292 of Senior Army Surgeon Shiro Ishii. 687 00:34:40,458 --> 00:34:42,958 Shiro Ishii was born in 1892 688 00:34:43,083 --> 00:34:45,373 into a wealthy family, a land-owning family. 689 00:34:45,500 --> 00:34:48,333 His father grew rice and made sake. 690 00:34:48,334 --> 00:34:51,374 Ishii, though, didn't want to follow in Daddy's footsteps. 691 00:34:51,375 --> 00:34:53,625 Instead, he wanted to go into medicine. 692 00:34:54,667 --> 00:34:59,167 He joined the army to become a military surgeon. 693 00:35:00,125 --> 00:35:03,083 Ishii was interested in studying cholera, 694 00:35:03,208 --> 00:35:05,125 epidemic hemorrhagic fever, 695 00:35:05,126 --> 00:35:07,457 bubonic plague- which was one of his favorites- 696 00:35:07,458 --> 00:35:09,542 but he also recognizes 697 00:35:09,708 --> 00:35:12,000 that you can weaponize these diseases, 698 00:35:12,208 --> 00:35:16,333 so he proceeded to examine biowarfare 699 00:35:16,458 --> 00:35:18,375 as an option for Japan. 700 00:35:21,250 --> 00:35:23,500 SHATNER: To test bioweapons for Japan, 701 00:35:23,708 --> 00:35:26,667 Ishii formed a military research group 702 00:35:26,750 --> 00:35:29,333 known as Unit 731. 703 00:35:30,250 --> 00:35:33,875 And between 1937 and 1945, 704 00:35:34,083 --> 00:35:36,667 they performed deranged experiments 705 00:35:36,875 --> 00:35:40,250 on thousands of prisoners of war and civilians. 706 00:35:41,542 --> 00:35:44,958 General Ishii was focused on the military research. 707 00:35:45,125 --> 00:35:48,167 But again, the atrocities are unimaginable. 708 00:35:48,250 --> 00:35:51,000 These were usually Chinese prisoners of war, 709 00:35:51,167 --> 00:35:54,833 but it was really any non-Japanese. 710 00:35:54,958 --> 00:35:58,917 He infected patients with tuberculosis, anthrax, 711 00:35:59,042 --> 00:36:00,833 all kinds of diseases, 712 00:36:00,958 --> 00:36:03,333 just to see what would happen 713 00:36:03,542 --> 00:36:06,833 and if he can find ways to make his soldiers immune 714 00:36:07,000 --> 00:36:09,292 or how to treat them. 715 00:36:09,417 --> 00:36:11,542 And this was his justification. 716 00:36:13,083 --> 00:36:16,875 SHATNER: It is estimated that Shiro Ishii's bioweapons experiments 717 00:36:17,083 --> 00:36:19,833 killed over 10,000 test subjects. 718 00:36:23,333 --> 00:36:25,958 After World War II, both Ishii and Mengele 719 00:36:26,125 --> 00:36:29,208 were never punished for their crimes against humanity. 720 00:36:29,375 --> 00:36:32,083 But ever since their horrific secret experiments 721 00:36:32,250 --> 00:36:34,000 were revealed to the world, 722 00:36:34,208 --> 00:36:36,000 we still don't understand 723 00:36:36,208 --> 00:36:38,000 why these deranged doctors 724 00:36:38,167 --> 00:36:40,875 would do such despicable things. 725 00:36:42,667 --> 00:36:46,125 One answer that Mengele and Ishii both offered 726 00:36:46,333 --> 00:36:48,625 was that they were doing it for nationalism. 727 00:36:48,792 --> 00:36:52,583 They were trying to further, perhaps, 728 00:36:52,708 --> 00:36:55,208 important military aims of their country. 729 00:36:55,375 --> 00:36:58,083 But I think, beyond that, 730 00:36:58,250 --> 00:36:59,833 part of the answer is that 731 00:37:00,042 --> 00:37:02,667 these two were clearly psychopaths. 732 00:37:02,875 --> 00:37:05,292 They enjoyed doing this. 733 00:37:06,500 --> 00:37:09,042 We really don't know what would drive a person 734 00:37:09,208 --> 00:37:11,917 to dehumanize another person. 735 00:37:12,083 --> 00:37:14,042 What happens in their mind? 736 00:37:14,167 --> 00:37:16,167 Do they snap for some reason? 737 00:37:16,375 --> 00:37:19,025 Is there some trauma inflicted upon them as a child? 738 00:37:19,208 --> 00:37:21,958 How could a scientist be drawn 739 00:37:22,125 --> 00:37:25,500 to this type of experimentation? 740 00:37:25,667 --> 00:37:29,625 I think this is one of life's great mysteries. 741 00:37:35,488 --> 00:37:39,332 SHATNER: Sitting on a lonely hilltop 742 00:37:39,333 --> 00:37:41,500 is an imposing stone fortress 743 00:37:41,708 --> 00:37:44,125 that dates back to the year 1252. 744 00:37:44,292 --> 00:37:47,458 Known as Castle Frankenstein, 745 00:37:47,625 --> 00:37:50,708 after the family who first laid claim to this land, 746 00:37:50,875 --> 00:37:53,500 legend says it is the location that inspired 747 00:37:53,708 --> 00:37:57,417 Mary Shelley's world-famous gothic horror novel. 748 00:37:57,625 --> 00:38:00,167 But surprisingly, Shelley's Frankenstein 749 00:38:00,292 --> 00:38:03,667 is not about the original 13th-century family. 750 00:38:03,833 --> 00:38:05,417 (thunder crashes) 751 00:38:05,583 --> 00:38:09,167 It is said inspiration for her mad doctor 752 00:38:09,375 --> 00:38:12,333 would come from tales of grotesque experiments 753 00:38:12,542 --> 00:38:15,167 conducted at the castle centuries later 754 00:38:15,333 --> 00:38:17,833 by an eccentric scientist named 755 00:38:18,042 --> 00:38:19,750 Johann Dippel. 756 00:38:20,708 --> 00:38:23,583 GENTILE: In 1673, in Castle Frankenstein, 757 00:38:23,792 --> 00:38:26,917 was born the perfect man for that name. 758 00:38:27,083 --> 00:38:29,167 That was Johann Konrad Dippel. 759 00:38:29,333 --> 00:38:32,167 He was technically a theologian. 760 00:38:32,333 --> 00:38:34,667 He went to college to study God. 761 00:38:34,833 --> 00:38:37,875 Dippel was a man fascinated with death, 762 00:38:37,876 --> 00:38:40,166 with other people's death, with his own death, 763 00:38:40,167 --> 00:38:43,875 and wanted to prolong his own as long as he could. 764 00:38:44,542 --> 00:38:49,208 He believed that the soul was a physical liquid 765 00:38:49,375 --> 00:38:50,917 inside the human body. 766 00:38:52,333 --> 00:38:56,000 And he procured cadavers, legally and illegally, 767 00:38:56,167 --> 00:39:01,333 to perform experiments on bodies in all kinds of ways. 768 00:39:01,500 --> 00:39:04,500 What it entailed was sticking a tube- 769 00:39:04,501 --> 00:39:06,416 usually made of animal intestine- 770 00:39:06,417 --> 00:39:07,708 into a cadaver, 771 00:39:07,875 --> 00:39:10,167 extracting the fluids from the cadaver 772 00:39:10,292 --> 00:39:13,500 and then transfer it into another cadaver. 773 00:39:13,708 --> 00:39:17,250 The goal being to reanimate that cadaver 774 00:39:17,417 --> 00:39:19,333 with this other one's soul. 775 00:39:19,542 --> 00:39:21,708 MORUS: It makes sense that, 776 00:39:21,875 --> 00:39:26,750 if the soul has a specific, physical location in the body, 777 00:39:26,875 --> 00:39:30,667 then you can kind of extract it, and- 778 00:39:30,875 --> 00:39:34,208 and put it- put it in another body. 779 00:39:34,375 --> 00:39:36,485 So about half a century or so previously, 780 00:39:36,500 --> 00:39:39,000 the French philosopher Ren� Descartes 781 00:39:39,208 --> 00:39:43,375 had developed a view of humans 782 00:39:43,542 --> 00:39:47,458 that the soul has a physical location inside the body. 783 00:39:47,625 --> 00:39:50,833 In case you're interested, your soul is there. 784 00:39:51,833 --> 00:39:53,523 That's where the pineal gland is. 785 00:39:53,625 --> 00:39:56,792 And the pineal gland, according to Descartes, 786 00:39:56,958 --> 00:39:58,750 is where the soul lives. 787 00:39:58,875 --> 00:40:00,000 But nevertheless, 788 00:40:00,208 --> 00:40:02,750 even by the standards of the early 18th century, 789 00:40:02,875 --> 00:40:05,667 if Dippel did indeed carry out 790 00:40:05,833 --> 00:40:07,958 these experiments on the dead, 791 00:40:08,125 --> 00:40:11,125 trying to transfer the soul 792 00:40:11,333 --> 00:40:13,833 from one body to another... 793 00:40:14,042 --> 00:40:17,417 This sounds, from our point of view, mad. 794 00:40:17,583 --> 00:40:19,833 BOESE: Like the famous fiction, 795 00:40:20,042 --> 00:40:22,458 these stories of horrendous experiments... 796 00:40:22,583 --> 00:40:25,583 they serve as cautionary tales 797 00:40:25,750 --> 00:40:28,292 about the pursuit of knowledge. 798 00:40:28,458 --> 00:40:30,750 You really have to ask: 799 00:40:30,917 --> 00:40:33,333 is the way science is being pursued, 800 00:40:33,500 --> 00:40:36,042 is it being done with wisdom 801 00:40:36,208 --> 00:40:40,958 or do we risk creating Frankenstein's monster? 802 00:40:42,000 --> 00:40:45,333 The mad scientist, for me, leaves me conflicted. 803 00:40:45,542 --> 00:40:47,542 We need to push science forward. 804 00:40:47,708 --> 00:40:50,625 We also have to maintain our ethics and our dignity. 805 00:40:51,500 --> 00:40:54,542 But there are experiments that may require us 806 00:40:54,667 --> 00:40:56,250 to forego our ethics, 807 00:40:56,417 --> 00:40:58,208 even if just for a moment, 808 00:40:58,375 --> 00:40:59,917 for the greater good. 809 00:41:00,125 --> 00:41:03,333 And I think that's why the "mad scientist" archetype 810 00:41:03,458 --> 00:41:05,000 will continue to persist. 811 00:41:05,001 --> 00:41:07,457 As long as we pursue the boundaries of science, 812 00:41:07,458 --> 00:41:11,583 we'll always be questioning our own boundaries as humans. 813 00:41:13,042 --> 00:41:16,750 Were Johann Dippel's attempts to resurrect the dead 814 00:41:16,917 --> 00:41:20,167 driven by ambition, curiosity... 815 00:41:20,333 --> 00:41:22,667 or plain old madness? 816 00:41:22,833 --> 00:41:24,667 Maybe it was all of the above. 817 00:41:24,875 --> 00:41:28,167 And it stands to reason that a unique combination 818 00:41:28,333 --> 00:41:30,667 of genius and insanity 819 00:41:30,875 --> 00:41:34,500 may also apply to other great thinkers throughout history. 820 00:41:34,625 --> 00:41:38,375 But no matter how potentially groundbreaking 821 00:41:38,542 --> 00:41:41,833 their outrageous experiments might be... 822 00:41:41,834 --> 00:41:43,707 they serve as a chilling reminder 823 00:41:43,708 --> 00:41:46,458 that the price of progress 824 00:41:46,625 --> 00:41:48,208 is often paid in blood. 825 00:41:48,333 --> 00:41:52,875 Whether it's ego or a warped notion of right and wrong, 826 00:41:53,042 --> 00:41:58,167 what ultimately motivates these mad scientists remains... 827 00:41:59,333 --> 00:42:00,917 ...unexplained. 828 00:42:00,918 --> 00:42:02,799 CAPTIONING PROVIDED BY A+E NETWORKS 829 00:42:02,800 --> 00:42:07,350 Repair and Synchronization by Easy Subtitles Synchronizer 1.0.0.0 64371

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