Original subtitles

Previously on Watson...

Five years sober is major.

You started rehab sophomore year

of college. I relapsed.

What you said about me last week.

You have no idea who I am.

I didn't label you.

I said you lie often and casually.

I told you something last week about my dad.

My interpretation is that you killed your father.

This place is sacred ground.

Why would this be sacred ground?

Oh, you tell me, Ingrid.

He's not down there anymore.

I have him now.

So you're collecting DNA?

Professor Moriarty would like similar specimens

from each of the fellows at the clinic.

You gave us fake DNA samples.

He says, no mistakes this time.

The patient's been asleep for 14 hours and counting

this time.

There's no mystery here.

I will bet you all a hundred dollars

this is Kleine-Levin Syndrome.

Mike Dwyer's in his 30s.

That's late for Kleine-Levin.

Unless there's

a trigger like this change-of-address form.

Patient's only been at his current address for two months.

That's when he started sleeping all the time.

Crofts, what do you see at the location?

Basement of his building is a shared laundry room.

But there's a subbasement.

Looks like an old bomb shelter.

Doesn't look like anyone's been down here

for quite some time.

Look at this.

That's black mold. Put your mask on!

Mike Dwyer is living on top

of a thriving colony of black mold.

Black mold contamination.

We'll monitor the patient while his body expels the spores,

and we'll give him a letter for mold remediation

once he wakes up.

Mystery solved, with plenty of time

to wash the mold off before dinner.

It's my fifth date with Nell.

Don't embarrass me.

When you're a kid with a twin,

your friends just want to know one thing--

if it came down to it, could you pass?

Same outfit, same hairstyle.

Could I pass for Stephens?

Could Stephens pass for me?

Oh, I can answer that one.

Absolutely not.

You sound so confident. I've dated both of you.

Who's more qualified to weigh in here than me?

So you're saying there's no way?

It's got nothing to do with clothes.

It's an energy thing.

You're Adam, you're Stephens.

Never the twain shall meet.

I'm so sorry. Um, I forgot to ask.

Could I see a list of your mocktails?

Of course, sir. Thank you.

We hated that question.

I did everything I could to set myself apart from Adam.

Unless, of course, it was Halloween.

Oh. What happened on Halloween?

On Halloween, we leaned into it, we wore the same costume.

I disappeared into Stephens

and Stephens disappeared into me,

and on that night we were one.

- Ooh. - Sorry.

Maybe you fooled eighth graders.

Guess what. Eighth graders are dumb.

We fooled everybody. I...

I got Adam grounded one year

because, um, our own mother couldn't tell who was who. No.

Honestly, we could pull it off right now.

I could be Adam for all you know.

I hope you're not Adam.

When you're a kid with a twin,

your friends just want to know if you can pass.

You just said that, babe.

Is this part of the story, or...?

Right?

Sorry.

So, it's not the same

as dating twins, but my friend

Joyce in New York-- she...

Surprise meeting?

Anybody got any guesses?

There's no plastic tarp on the floor.

We're not getting whacked.

He didn't tell you either, huh?

Dr. Morstan, wow, Watson invited you, too?

I resisted the urge to bring an attorney.

No, there's no calls for a lawyer

because we're here to... celebrate.

The Holmes Clinic

attracts people from all over the world.

As you all know, almost every patient

that comes through here donates a DNA sample.

A consensual, anonymous contribution

to the world's body of knowledge.

We're not just helping people.

We're building a library.

I have been working on a project

to put that rare DNA we collect

to use for the good of the species.

"The Watson Database of Human Mutations."

It's my life's work. It's our life's work.

There's going to be an article in the New Scientist next week.

This clinic

is the hub for a project

cataloging every mutation known to mankind.

So once that paper comes out, this place is gonna be a magnet

for mutations from all over the world.

It's going to be very busy in here.

Shinwell's going to need some help.

Anyone heard from Shinwell?

The man's never missed a day of work.

We're all listed as authors.

We shared the work,

we should share the credit.

Excuse me.

Can I help you with something?

I'm sorry to interrupt.

I've been having migraines, and my ENT said

maybe I should come here for a second opinion?

I'm sorry, we don't take walk-ins here.

I'll see him.

If he's having headaches,

we can't let him walk out of here without a neuro workup

'cause it could blow back on us.

Okay.

This place is awesome.

Thank you.

What do you want? Relax.

I'm here to set you free. What does that mean?

Don't talk in riddles.

Dr. Watson curates a cutting-edge

genetics lab but 20 feet from here.

I'm sure he's growing some

adeno-associated virus for his experiments.

That's a viral vector.

I know what adeno-associated virus is. Good.

All you have to do is find the samples he's growing.

Pour the contents of these packets

into each and every culture dish.

You want me to sabotage Watson's research.

Why? Just do it for me.

And then you're free.

I don't believe you.

There's no way that's the only thing you want me to do.

This place has got you confused, Ingrid.

You were born to be a certain kind of person,

and you're fighting that.

You can be who you are.

Is this the last thing I'll ask you to do?

Of course not.

But everything after this will be easy.

Are you him?

Are you James Moriarty?

Of course I am.

Dr. Watson thinks my fingers are webbed.

It's all just sleight of hand, really.

If a geneticist is chasing you, show him syndactyly.

Direct his eye where you want it to go.

I did all this so I could introduce you to yourself.

Have you seen your brother?

Uh, no. He's not back from lunch yet.

Why? I just got a very strange phone call

from the nurse's station on six.

- Can I have my purse back? - This one...

Hey, come on, now, Dr. Croft.

Adam, what the hell are you doing?

He picked up my bag and just started digging through it.

What's the matter with you?

I-I'm-I'm-I'm not, I'm not done... Adam.

Dr. Croft!

I need to take this.

Okay? Listen, we're gonna get

a room ready for you, you can rest there.

- I was looking at that. - I understand.

It's gonna be okay.

We need to admit Dr. Croft.

Be gentle, but I want you to check his vitals

and take his blood and urine for a tox screen.

A tox screen? Adam's been sober for five years.

We're looking at the same picture, right?

Obviously, this is strange, but Adam was exposed

to black mold yesterday. Stephens,

we are gonna consider everything,

but we can't ignore the obvious.

I have to run a tox screen.

We have to consider the possibility

that Adam is having a relapse.

How's the weather over there?

I can tell

when things are cloudy in your head.

Are you okay?

I'm fine. Thanks.

Ingrid.

What's going on?

I need everyone

in the conference room.

We have a new patient.

My brother needs help.

What's wrong with Adam?

Is he high? No. Adam is sober.

He has a history of addiction.

He's experiencing short-term memory loss,

lowered inhibitions.

We can't ignore relapse.

I have a diagnosis for Adam.

He's annoying, and I say that with all love and respect.

Can you call someone "annoying" respectfully?

If he's your identical twin, yes, you absolutely can.

Look, my brother takes recovery very seriously.

I don't believe that he's high,

but Adam has already given blood and urine

for a tox screen.

It'll show what it shows,

but I don't want to sit around waiting.

Why are you looking at me?

Your colleague has conviction.

You said

Adam was exposed to toxic mold yesterday?

I mean, who knows what else was in that bunker?

Sounds like a mycotoxic playground.

What did Adam eat last night?

Some sort of...

overpriced, pretentious vegan mush.

Definitely looked capable of causing illness.

With your permission,

here's what I propose.

Dr. Croft, you head back to the subbasement.

Take pictures and catalog anything

that could account for Adam's symptoms.

Sasha, you can see what you can learn from the restaurant

and you can help Stephens.

Ingrid, you can supervise Adam's tests.

Rule out trauma, stroke, or any other lesions.

If the tox screen comes back negative,

then we'll have a head start.

Sound good?

Thank you.

Your brother's lucky to have you.

It's Adam.

There's a bandage on my arm.

You drew blood.

Watson's running a tox screen,

but it's a precaution.

A precaution.

That's good. We're not waiting around.

We'll figure this out.

It's gonna come back positive.

What? Tox screen.

It's gonna come back positive for hydrocodone.

Lauren had her wisdom teeth out.

She had a prescription for it.

She was traveling last weekend and...

Lauren forgot it was there, I forgot it was there

until I went looking for toothpaste.

I had the weekend to myself.

I took six pills over two days.

It was a relapse, Stephens.

You're getting engaged.

You have a book coming out.

Why?

Because I have a book coming out?

Because I'm getting engaged?

It's addiction. There's no logic.

Stephens.

It's Wednesday.

I took the last pill Sunday morning.

I'm gonna test positive,

but I-I wasn't high this morning.

I don't know what's going on.

Should I tell Watson now?

N-No. No way.

We still have a few hours to figure this out,

and I want to know what's happening

before the results land,

so no one thinks that you were high at work.

You made a mistake.

We'll deal with it, Adam.

Thank you.

Seriously.

- I'm sorry - I wouldn't talk to you before.

I was scared.

The blackmail.

Uh, hold that!

Thanks. Mm-hmm.

Oh, hey. How are the, uh, the headaches?

Oh.

I'm feeling great. Thanks for asking.

Mm.

That, uh, doctor was very generous with her time.

I'm grateful. Okay, good, good.

It would feel so good to tell you all about it, Sasha.

But here's the thing--

we all have a circle of people we're looking out for.

It can only get so big.

I'm taking care of me and my sister.

Doesn't sound like much.

But it's enough.

If I'm not careful,

if I let it grow...

...soon I'm taking care of everyone.

And that's the same as taking care of...

no one at all.

I, um...

wasn't trying to eavesdrop.

I guess I walked in at just the right time.

But what you're doing at your clinic...

sounds incredible.

A database of human mutations.

Wow.

You overheard a lot.

Enough to be impressed.

But don't be nervous-- I'll never tell.

You're a good person.

You haven't had to learn the things I've learned yet.

Um, thank you

for what you're doing for all of us.

We'll probably never meet again, but...

...I'm a big fan.

Thank you.

It was fun to picture a different version of me.

But she can never be real.

John.

Did you learn anything about Adam?

Not yet. We're still working a few different angles.

I asked to be the first one to see his tox screen.

He's a doctor in my hospital. I have to know if he's high.

I'm sorry, John.

He tested positive for opiates.

We'll test again.

Keep looking for anything that might help.

But with what I'm seeing right now,

I have to treat this as a case

of workplace intoxication.

I should tell Stephens before we do anything.

He's gonna take this hard.

This is Watson.

The OR?

Be gentle.

We're on our way.

Dr. Croft just wandered into the operating room.

Okay, that is a dangerous tool.

I need you to put that down.

Come on, it's all right. Put it down.

I need you to put that down. Excuse me.

Adam. That is a dangerous tool.

We were prepping the OR when he came in.

It's like he can barely hear us.

You need to give that back to us.

Stephens?

What are you doing?

Have you seen this thing?

It is absolutely incredible.

All right.

Okay, let's give that a rest.

Okay.

Here we go.

You're okay.

My son loves remotes...

Now that they're both presenting with the same symptoms,

we have to reconsider everything we thought we had observed.

Dr. Derian, what are you seeing?

Hypermetamorphosis.

That's why they're losing their minds

about everything.

Extensive attentiveness

to visual stimuli,

with a tendency to touch each stimulus.

You'd think he'd never seen a mug before.

Or he doesn't know he has. Visual agnosia.

Yes, Dr. Morstan.

Their eyes are working...

But their brains aren't processing what they're seeing.

We've witnessed

all of these symptoms.

Plus disassociation.

They're dissociative during these episodes.

And then suddenly lucid again and back

to their bickering selves.

Oh.

Something's happening.

Dr. Croft, you can't eat that.

Don't put that in your mouth.

Doctor, please. Where'd they get all this?

They pulled a meal cart in from the hall.

As in the collection cart?

They're eating other patients' leftovers?

Hyperphagia. Insatiable eating.

Book the MRI stat.

They just had MRIs. I know.

For the results to be different, their brains

would have to be changing rapidly.

I know, Ingrid, I need you to move fast.

Book the MRI.

You were right. They changed.

In four hours their temporal lobes changed.

These angry-looking signal abnormalities.

Exactly. Pica coexists with the Crofts' other symptoms

in just one diagnosis.

Klüver-Bucy syndrome.

What's the prognosis?

Cascading brain damage unless

the underlying cause is treated.

It's fatal? Okay, Sasha, just stay here.

- Underlying cause. - Uh, neurosyphilis.

Meningitis.

Stroke. Syphilis

and meningitis tests are all negative.

Pick's disease. West Nile. Tumor.

We can likely rule out twin tumors.

You both are missing one major cause.

Herpes simplex encephalitis.

Adam did have a cold sore.

Well, rarely the virus can ascend

to the brain via the bloodstream or a nerve.

No one actually knows how.

So, Adam passed it to Stephens?

You know, I've seen them both

drink out of that mug.

They'll never admit it, but they're both dying

to be number one.

Yeah, that's why I've never seen either of them wash it.

So, it's good news.

How did you hear Klüver-Bucy syndrome as good news?

A serious diagnosis,

but of all the root conditions,

herpes simplex is one of the most treatable.

Two weeks of antivirals and...

you both should be back on the road to recovery.

Thank you, Watson, for figuring it out.

If he did.

Lauren's been in the waiting room all day and all night.

I'll update her, and hopefully

we can get you all home as soon as possible.

Can't wait.

Aren't you worried about 'em?

I am.

But the treatments should help.

We're just not that alike, are we?

You and me.

I can't tell if I should be more like you,

or if that's the last thing that I would ever want to be.

Good night, Dr. Derian.

Be you.

I can't do it.

Hi.

Still no Shinwell?

I thought he was with you.

How did you get here?

An Uber that smelled like burritos and cigarettes.

I'm starting to worry about Shinwell.

Not to add to your concern

when you're barely through the door,

but the Crofts aren't responding to the antivirals.

Have you added a course of corticosteroids?

Corticosteroids and foscarnet,

and with all that, somehow their viral load is increasing.

They're positive for the herpes virus,

but it's antiviral and steroid-resistant?

It makes no sense.

Add to that how rare it is for the virus

to cross the blood-brain barrier in the first place.

And it happened to both of them.

Something's really off here.

I need you to sequence

a sample of the virus itself. On it.

I'm gonna call in a welfare check on Shinwell.

I don't like the timing of this.

IV bag of vescalagin?

They're officially throwing spaghetti against the wall.

That negativity isn't helpful.

Neither is the fallacy of positive thinking.

Our episodes are getting longer, harder to bounce back from.

None of the treatments are working.

Not accepting the reality of the situation isn't heroic.

It's idiotic.

You're the one who's idiotic!

I see your disinhibition has returned.

Why don't you get it all off your chest?

You are the twin who is

objectively smarter and better in so many ways,

yet people always choose me over you.

Do you know why?

Because they suck at multiple choice?

It's because life is one nightmare after another,

and this situation that we're in right now is a perfect example,

and in the depths of a nightmare,

who would you rather be around?

Is the answer you?

Someone who makes you feel better

or someone who, guaranteed

time after time, makes you feel worse?

What does it matter what you feel

if you're still stuck in the nightmare?

It changes how you survive it!

I have a hard enough time getting out of the darkness

without you... dragging me back in.

Hope isn't idiotic, Stephens.

For most of us, it's necessary for survival.

The results are in.

Look at this.

At the top is

standard herpes virus.

The bottom is the Crofts.

That doesn't look like something that occurs in nature.

It's not. It's been genetically modified.

Someone made this virus. But who?

You, guv.

You made this virus.

Well...

...we did.

What?

Where have you been?

There's a lot that's been needing explanation,

so I've been off trying to put it all down, pen to paper.

But I knew I owed you a conversation.

Or at least the chance to spit in me face.

Your research made the Crofts sick, guv.

It's Moriarty.

You were right.

By either cunning or black bargaining,

he survived the trip over the waterfall.

And I've been doing as he asks for months now.

The man has his hand in your life's work.

Every entry in the database of human mutations,

he has it, same as we have.

Adam Croft overheard something he shouldn't have.

It was nothing, forgotten about

as soon as I spoke it aloud.

But Moriarty,

he's not one to leave a thread un-snipped.

I believe Adam's the target here.

Stephens, he's... he shares the same DNA, don't he?

So he's just collateral damage.

Don't know how he does it, guv,

but, uh, you'd be the one to tell me.

All that DNA you're keeping downstairs,

Moriarty knows how to...

turn it against people.

John.

I need you

to say something, you know.

Anything.

All this time...

...with me, with Holmes...

...that was a lie.

Far from it.

You and Mr. Holmes showed me

a better way to live. Then, why?

I came up hard.

It's an ugly life.

But there are those that...

...loved me along the way.

Moriarty intends to kill them both,

if he hasn't already.

John, I need you to tell me how you want this to go.

Tell me to help.

Tell me to lay down my life in service of the Crofts,

'cause I'll do that.

Tell me to turn myself in. Just tell me anything.

I'll leave.

It's all there.

The whole story.

Yeah. Give him a minute, yeah?

He'll be down soon enough.

Everything all right, Shinwell?

It's been my privilege.

This is a good place you got here.

You're all in danger.

The safest thing for everyone in this room to do is to tender

your resignation and go home.

Why are you saying that?

The DNA that we've been collecting, the...

the work that was supposed to change everything...

...it's in the hands of someone evil.

It's a weapon now.

And that weapon has been turned against Stephens and Adam,

and it could be turned against any one of us.

A man named James Moriarty

has your DNA.

He has everyone's,

and he could use it to kill you.

Anything you breathe in, anything you touch

could be a vector.

It could carry a designer pathogen

made to end your life.

I thought that we were building something to help everyone.

But really we are just a factory.

We mass-produce murder.

Stephens and Adam are dying.

You want us to leave you to help them by yourself?

I want you to make an informed choice.

I'm not going anywhere.

Yeah. Neither am I.

All right.

I don't know what's next. I don't have any orders to give.

But if you're gonna be here with me,

we're gonna figure this out together.

Well, we worked.

While you were upstairs,

we worked.

We brainstormed genetic conditions that could be

magnifying the effects of the virus,

then we took our database

and ran the Crofts' DNA through that filter.

Expecting to see something affecting their immune system.

Instead, we found this.

A SNORA31 mutation.

A mutation on this gene

basically destroys the body's ability to...

Keep viruses out of their brains, yes.

Occurs in roughly 0.001% of the population.

Dr. Lubbock, Dr. Derian,

you have found a needle in a haystack.

Two people with a mutation this rare getting hit

by an unkillable version of their own kryptonite... it is

statistically impossible.

You were right.

This was made for Stephens and Adam.

Exactly.

Dr. Morstan...

...you fired me.

You found out what I did for my sister,

and you tried to force me out.

If I stay here...

...am I still fired?

I'm sorry. Are you negotiating?

Dr. Derian, in light of circumstances,

I'll move you to probationary status.

Any suspect behavior and you're terminated.

Okay, look, you're all here now,

and I will never stop

being grateful.

For now let's find a way to kill the unkillable.

Thank you.

There you are.

Stephens.

What is this?

What-What's happening to us?

They're on top of it.

You know, if anyone can fix this...

Fix this?

What happens if they can't?

Adam, we don't know...

If you're about to attempt encouragement and optimism,

please spare us both from that train wreck.

I got smug, Stephens.

All those years of meditation...

Zen,

metaphysical this, spiritual that,

here I am, still just...

...terrified.

Adam...

Again, it's not the time to try out

a Mister Rogers routine.

No Mister Rogers.

It's just the facts.

No one, no one knows

what's on the other side or if there is an other side.

I don't think that there is.

Yep,

that's definitely not Mister Rogers.

But that doesn't mean we just end.

What's the first law of thermodynamics?

I swore off physics in undergrad.

Energy cannot be created

or destroyed, it can-- can't go poof,

it can only take another form.

In this job,

I've seen people die.

And I don't need to believe in Deepak Chopra or Santa

to know that, in that moment, something--

call it energy-- leaves the body.

And in my bones,

I know that that energy doesn't disappear into the void,

just as I know that water in a puddle doesn't.

Despite comparing my soul to a puddle...

...that's pretty good.

Adam, I'm scared, too.

But I don't think we just end.

The body, the consciousness-- the bells and whistles-- sure.

But the engine at the heart of it,

the heart beneath the heart,

whatever it is that really makes this whole thing tick...

...that can't be destroyed.

Adam?

A-Adam? Adam.

Nurse.

Nurse?

Dr. Croft?

Dr. Croft?

I need an EEG tech in here.

What's going on?

We won't know until we run an EEG.

Lana.

Adam's fallen into a coma.

Dr. Grant Howard to Trauma.

Dr. Grant Howard to Trauma Two.

Hi.

Dr. Lubbock.

In violation

of PPE protocol, no less.

Well, I'm a Texas gal with a rebel soul.

Hmm. And y'all ain't catching.

Lauren dropped these off for y'all.

There's one for me. Thank you, Dr. Lubbock.

I'll, uh, read Adam's letter to him.

I should, uh, I should get back.

I always assumed that we'd have plenty of time.

Yeah.

Me and you.

To be or become whatever we were going to be.

Not that I was making any assumptions.

I just hoped we'd find the right moment.

Me, too.

Maybe this is the right moment.

It's not the one I imagined.

I figured it would involve...

candlelight or a sunset,

at least a Ferris wheel.

Oh. Stephens.

If this is our moment, I will take it.

Have you been here all night?

Get a load

of that fella.

Hiding in the neurons so we can't get to him.

So we'll need to offset for hepatotoxicity.

Last month scientists used a meganuclease enzyme

to cut this virus out of healthy brain cells.

Watson, this is encouraging, but they've only done this once,

in lab mice.

We're inventing a new cure here, Dr. Lubbock.

There's not gonna be a lot of precedent.

Okay, so how do we get

the enzyme to the virus?

We drill into the skull, obviously.

Obviously.

And from there, this guy

should take us exactly where we need to go.

What is that?

Tiny scissors.

Tiny scissors? Oh, yeah, tiny scissors.

It's a WAVE9, it's a viral vector

I've been tinkering with for gene editing.

This is our delivery system for the enzyme.

It goes after all the neural viruses,

and the accuracy is deadly.

Guess which enzyme it carries inside.

This could work.

This could work. This could actually work.

Oh, yeah, you bet it could.

I'm gonna go tell Stephens.

Dr. Croft.

Oh...

Dr. Croft.

Dr. Croft.

Lana?

He's not responsive. I'm sorry.

Understood.

Understood.

You have my word.

Listen. I need to talk to you.

I need approval.

It's a procedure to save the Crofts.

Now, it's untested and it's dangerous.

If something goes wrong...

Do it. Mary,

it could blow back on the hospital,

and it could blow back on you.

Just do it, John. Save them.

I got you.

Great. Thank you.

Dr. Doherty said he's ready to drill some skulls.

He'll do the surgery.

I knew he'd want a shot at the record books.

The next available OR slot is at 1300.

Take it.

Put us in.

Dr. Lubbock,

prepare a saline base.

On it.

Dr. Derian, dose us up.

Target seven micrograms

of our tiny scissors per unit.

Where are the cultures?

In the incubator. Base level.

Everything okay?

Those are adeno-associated virus.

I thought you called them WAVE9.

Yes, Watson adeno-associated viruses, type 9.

WAVE9 for short.

Where are my cultures, Dr. Derian?

What's going on?

It's dead.

It's also dead.

Okay, well, I-I'll call around.

Another lab's got to have it.

No, I made these. No one else will have them.

Okay, then we grow more.

That's gonna take weeks.

The Crofts will be long gone by then.

Let's see another one.

Also dead.

The incubator was turned on, as it has to be.

Okay, so...

I, uh...

I centrifuged everything that was left in the culture dishes.

That gives us a usable amount of vector.

Wait.

Seriously?

Watson?

There's only enough for one dose.

We can save Stephens or we can save Adam,

but we can't save both.

Who?

That's up to us.

But we have to choose.