Original subtitles

Previously on Watson...

The Crofts aren't responding to the antivirals.

Dr. Croft?

They're positive for the herpes virus,

but it's antiviral and steroid resistant?

And it happened to both of them.

That doesn't look like something

that occurs in nature. Someone made this virus.

All that DNA you're keeping downstairs,

Moriarty knows how

to turn it against people.

I believe Adam's the target here.

Are you James Moriarty?

Pour the contents of these packets

into each culture dish.

You want me to sabotage Watson's research.

What's going on? It's dead.

There's only enough

for one dose.

We can save Stephens

or we can save Adam,

but we can't save both.

A database of human mutations.

Sounds incredible.

Thank you for what you're doing.

I'm a big fan.

There are moments when we all have to make a choice.

We have treatment to save one life:

Stephens' or Adam's.

You're talking about identical twins in their 30s.

They share the same DNA.

Stephens and Adam are

effectively the same person.

Not really.

Adam practices functional medicine.

Stephens is an infectious disease specialist.

Adam is an addict who just had a relapse... Stop.

None of this means that we can just pick.

Sometimes the ethics are impossible.

Sometimes there's no way to find daylight

between two human beings.

This... came from Sherlock.

Fate has to decide here.

Hopefully, Sherlock's wisdom guides it.

Are you awake?

My brother?

Good to see you.

Where's-where's Stephens? Is he okay?

This is wrong.

You should have picked Stephens.

I can't help you figure this out.

My brother could.

Stephens doesn't deserve this.

Do you?

So, what now?

Now we just wait and watch my brother die?

We have time.

Two days, maybe three.

There's lesions growing in his brain.

If we operate on Stephens two days from now,

what's gonna be left of him when he wakes up?

- I don't know where you are, - I don't even...

know if you'll be able to hear this, but...

my guess is that you're off somewhere punishing yourself.

And if you are, you got to freeze that,

because if the odds hold,

we'll all have time for guilt.

So if you think that you can help, we need you.

Stephens needs you.

John.

You all right, Shinwell?

You look sick.

I got your message.

There may be a play, guv.

If you're truly willing to work with me...

...I may be able to help.

Your daughter's dying.

You don't know that.

I know she ain't been discharged.

I know you ain't slept in days.

You know what, my love?

Them dark circles,

they make you look positively human.

What do you want?

Dr. Watson extends an invitation to you and your daughter.

He wants to have her into the clinic,

see what can be done for the lass. I'm not one to fall

for snake oil, Shinwell. Yeah, well, that's good,

because we don't sell fake cures.

John Watson might be able to help her, he might not,

but he's the best medic in this or any other hospital.

If you don't at least hear what the man has to say,

have you really done everything you can?

I know you.

You're the pharmaceutical rep that used to sit over there.

Yes.

And you had no idea.

Welcome to the Holmes Clinic, Ashleigh.

I'm excited to work with you.

What is this?

What do you think it is?

We're taking on a new patient. My daughter is nine years old.

She's been through more pain and disappointment

than you or me or anyone I've ever met.

I haven't been able to protect her from that,

but I can protect her from false hope.

I don't traffic in false hope.

What do you want from me?

I don't want anything.

Not yet. I don't believe you.

My name is Dr. Morstan.

You can call me Mary if you want.

Have you ever had a doctor who had his own robot?

A robot? Mm-hmm. We have one here.

His name is Clyde, and he helps Dr. Watson do his job.

Is it okay if I show you?

Okay.

Does he ever take a break?

He's never asked for one.

He does look a little tired.

Medulloblastoma, subtype SHH.

This girl had a brain tumor by her ninth birthday.

That's just not right. We should get a rush from the labs.

How's this meant to work, Shinwell?

You take Ashleigh into your care,

tell us the same thing we've heard from a dozen medics,

and I just share everything about him?

We don't need everything.

Just one thing.

That's Stephens Croft.

It's not Adam Croft.

It's not the one you targeted.

He just happens to share the same DNA as his brother.

Somewhere not far from here,

there's a laboratory where Moriarty's busy at work

on his perversions.

The vector to deliver the cure,

far as I understand it, is called

"adeno-associated virus."

If you're cooking up a bioweapon,

any scientist would have

some small amount of the cure on hand, too.

That's what we need.

Enough of that virus to save Stephens Croft.

Oh, that's all?

It's suicide to cross Moriarty.

A nine-year-old with brain cancer.

Those words don't belong together in one sentence.

You're not wrong, but it could actually be worse.

There's a treatment. Neurosurgery.

Chemo placed directly into the brain.

I didn't say it was good. I said it could be worse.

With chemo, there's a 90% survival rate for this patient.

Our immediate problem isn't the tumor.

If we can get her into surgery,

Ashleigh has a good prognosis.

The problem is her weight.

The chemo that she needs is weight-based.

If she can't get heavy enough, then her doctors

can't use enough chemo for the treatment to be effective.

If we could put 15 pounds on Ashleigh Burke,

we can save her life.

And if we can't?

She has good doctors.

Obviously, they can see the same thing we can.

Okay, so what are they missing?

Come on. I mean, a single insight

could make a big difference.

No one can figure out why she can't gain weight.

So, where do we start?

I don't think Ingrid's talking about the medicine.

We want this girl's mother to steal what we need

to save Stephens.

If she won't do that, if she can't do that...

If there's nothing

we can do to help,

do we sell her mother on a treatment

even if it's not gonna work?

Could you do that?

We're not dealing with the leader of a Brownie troop.

Ashleigh's mother is the reason

Stephens got sick in the first place.

But if we say that we're Ashleigh's doctors,

then that is who we are.

If the words don't mean something to you now,

then they've never meant anything to you

in the first place.

So again, where do we start?

Uh...

Watson?

Can I help you with something?

I'm looking for a Dr. Watson.

I'm John Watson.

My name is Laila Bynum.

I'm Ashleigh Burke's oncologist.

What is this place?

We are lucky with our funding here.

MRIs, genetic testing.

We can do a full workup and keep digging.

Ashleigh might not have time to wait

for genetic tests to come back.

This clinic is a resource. We will work with you

to do what's best for your patient.

Hmm.

You seem skeptical.

I'd like to know who you are.

Think I've been pretty forthcoming.

But you can ask me anything you'd like.

I spend all day, every day at a place

most people hope to never see.

I can't even imagine.

Pediatric oncology is a breed apart.

They try and teach us coping mechanisms.

None of it works. Not really.

You pick this, and you're going on a ride

with each and every patient.

It can end at a graduation,

or it can end at a funeral.

I'm not vain.

I'm open to a second opinion.

But parents get desperate

when things aren't going as they hoped.

They fall in with people they shouldn't.

Is that you?

No.

This girl is up against it, Dr. Watson.

These next few weeks could be all she has,

and she needs someone who's going to make them matter.

It sounds like she needs you.

That's it. I'm done.

The program requires another set of band pulls.

The program also says not to push too hard.

I know the surgery is soon.

I'll be ready.

Do you know that guy? He keeps looking over here.

He's from work. Give me a minute.

What are you doing here?

Was it a relief?

When you did what I asked.

When you opened those packets and poured them on the vector,

was it a relief?

I wouldn't use that word.

It was more...

inevitable.

You can use this number to reach me.

This isn't about orders anymore.

It's a collaboration now.

I've been wrestling with this idea.

If this keeps going the way it's going,

there are things I won't get to say to you.

I see you, Stephens Croft.

I love that you're hurt

and that you try and protect yourself by hiding that

and never letting anyone know who you really are.

I love that you can't quite do it.

And I love every flash of kindness

you can't quite keep inside.

I hope you come back to us.

But if we don't get that,

I... hope you can hear

what I'm saying to you right now.

And I...

I hope you remember this.

What's happening?

She's seizing.

Why? What is this?

He's having a non-convulsive seizure.

We need IV propofol stat.

Give me 0.1 migs per kigs of lorazepam.

Help me keep her on her side so she doesn't choke.

I'm sorry, Ashleigh's had a seizure,

and that's meant to be good news?

The good news is that her cancer didn't cause the seizure.

Your daughter's tumor is on her cerebellum.

A seizure like the one she had is a cortical event.

There's a secondary cause to her weight loss.

When we can figure it out, we can help her.

We can get her to surgery.

There's something else you need to know.

Stephens Croft almost died today.

The HSV1 that you infected him with

is cooking his brain.

We're-we're taking all the blood out of his body,

we're putting it through a machine,

and we're cooling it down by five degrees.

It's a Hail Mary and a way to buy time.

What do you want?

You know.

You're going to get us

the adeno-associated virus that we need to cure Stephens

because we're doing everything in our power

to save Ashleigh.

But if Stephens Croft dies,

I will wrap my hands around your neck,

look you straight in the eye

until your entire world turns black.

We're not trying

to diagnose the man.

We just want to know where the lab is.

He has extensive holdings.

I don't think he'd risk

those samples.

Could get damaged in flight,

could be inspected.

That facility is in Pittsburgh or somewhere close.

What's he doing?

I can't be the only one who's wondering that.

All the DNA that we've collected, our work.

How many people are gonna die?

The man's genius lies in recognizing a tipping point.

If the eight people

in the line of succession all die

at once, of a mysterious ailment,

what would that do to a country

grown fat on conspiracy theories?

If the heads of the wrong country

in a sensitive region all died on camera...

...what would that do?

Moriarty won't kill many people.

He'll kill the right people.

Have you seen anything unusual lately?

Have you done anything unusual? There's nothing's too small.

I had extra duties.

What, uh, three months ago?

I was asked to coordinate a series of deliveries

from a company called Authentic Aromas and Spices.

AAS is a conglomerate.

And they're one of the world's

leading suppliers in laboratory equipment.

Wherever those deliveries went, that's probably your lab.

You okay? Yeah. Sorry.

Okay, listen, you two, you go to that address,

make sure it's the right one,

make a plan to get what we need.

Make a plan?

Do you have a problem with that, Dr. Derian?

I think James Moriarty is smart enough

to protect his lab.

I don't think that whatever's left of Shinwell

and Nigella the dainty British bitch

are gonna make it through the front door.

This is a suicide mission.

Thank you for the input.

Shinwell, I need a minute with you.

Yeah, I'll be right up, guv.

Not in my office.

Must be agony.

Moriarty cooked something special up for me, eh?

We'll have to do a full workup.

No.

Your attention just happens

to be the most valuable commodity

in the world right now.

I'll not divert a dram of it,

not until the Croft boys are well.

You can still do what you need to do?

John.

How are you?

The Croft boy, Moriarty,

the DNA-- it's a lot.

I'm fine.

Ashleigh Burke had

a grand mal seizure this afternoon.

We did a head CT-- it didn't show any changes,

so we don't think the seizures are related to her cancer.

Was this her first seizure, or was it

part of a pattern? She's never had anything

that looked like a seizure before.

There might be an infection.

We should look for sepsis.

Run a CBC and blood cultures,

a Chem 7 to find any

electrolyte abnormalities.

If it's all right with you, Dr. Bynum,

I'll check on Ashleigh, get her ready for the needles.

She's used to them by now, but a friendly face helps.

Thank you. Yes, of course.

Okay, so let's get this in motion.

Now, remember:

Ashleigh's 15 pounds away from a full and happy life.

How'd you get this way?

What do you mean?

Most doctors run through a checklist

and then head home to watch the Penguins game.

This attitude I'm seeing here,

where'd it come from?

Well, let's just say it comes from

a man named Sherlock Holmes.

He played the violin, had a weakness for cocaine,

and he died by falling over a waterfall.

I might want to hear that story sometime.

Any thoughts on how we do this?

We wait till shift change in the morning.

It'll be less suspicious then.

I've been sent to do a spot check.

There's another way.

I go in there.

No ruse, no conversation.

Nothing but me...

...and the things I know how to do.

You feel like dying tonight, Shinwell?

If I go into that building

and I don't come out...

...feel free to indulge yourself in a last stand.

Why do you believe in this man?

Dr. Watson.

If Ashleigh can be saved,

he'll save her.

No matter what else you done,

you done right by that girl.

So, is this, like, your spot?

I'm glad you reached out, Ingrid.

What's on your mind?

I'm done fighting.

I'm done pretending

to be someone I'm not.

You're right.

It does feel better.

It's the clinic.

There are things happening there.

Things you should know about.

You took too long to kill Shinwell.

A knife or a bullet would have been better than your new toy.

They know about your lab.

If there's anything there that you want to save,

my advice would be to work quickly.

Something bothering you, Ingrid?

I want to know what this is.

People like you and me, we've been lied to.

The things that are supposed to mean something--

uh, building a legacy, helping other people--

that's all a part of the lie.

How far can you extend your will into the world?

That right there,

is the question that matters.

Only a few of us get to see that.

Welcome to the only club that matters.

None of this makes sense.

Ashleigh Burke doesn't have sepsis.

Her CBC and cultures are negative.

Every test is negative. Why can't this girl gain weight?

Sorry.

Had to deal with Gigi stuff.

I'll catch up by listening.

That couldn't have been her first seizure.

She's burning off every calorie you feed her.

We don't bleed our patients with leeches,

and we do check if they have seizures.

Sorry.

Defensive.

We've had Ashleigh on the leads.

Of course you have.

But, listen, we have staffing issues here.

Every hospital does, especially for shift work.

Has there been a change on Ashleigh's floor?

They caught two night nurses in the supply closet.

They were good.

Sometimes good is horny.

How do you rate their replacements?

It's contract workers right now.

All right, so the leads that are connected to Ashleigh

to monitor whether she's having

late-night seizures have been attached lately

by new and untested workers.

Do you think it's possible

that she's been having seizures

but the nurses have just missed them?

That could explain Ashleigh's weight loss.

Watson?

You with us?

I am with you.

I'm also hungry.

Sorry. Stephens is dying,

Shinwell's parked outside of some heavily guarded lab,

and we're also dealing with a nine-year-old with brain cancer.

Well, you're not wrong.

Sometimes the universe tells you a really good joke.

I believe Ashleigh Burke has

a genetic condition called MCAD.

Medium-chain acyl-coenzyme A dehydrogenase deficiency.

Very good, Dr. Lubbock.

Say that six times in a row, and you will get

your very own meal replacement shake.

I'm good, thanks.

You did your job perfectly.

You gave her the very latest in meal replacement shakes.

They have MCT and coconut oil in them.

The problem is, Ashleigh's body can't process either of those.

She has seizures at night and only at night

because that's when her body burns up all the fuel.

And the new temp nurses failed to detect them.

So she just needs an old-fashioned protein shake?

It's still just a theory, but if I'm right,

her body can process those.

We need to give her corn starch every night.

It's packed with calories and carbs.

It gives her body the energy that it needs.

And she won't seize.

Corn starch?

And we're not there yet,

but I think we just saved one life.

We're nearly there now.

Give them a few minutes to get their day rolling,

and that's your window.

Hannah.

That's my name.

If I don't come out of that building,

if Ashleigh lives and I don't,

it's more than I have any right to ask.

More than I deserve. Listen to me.

If I get through this and you don't,

she will remember you.

She'll think well of her mum.

I promise ya.

What is this?

They know we're coming.

It wasn't me.

It don't matter.

It's a different cricket match now.

In a pinch, guv.

We haven't been to the lab yet.

I need you to come back to the clinic.

John, I don't understand.

Understand it later. Come back right now.

Good. You're safe. I'm glad.

Guv, we didn't get what you need.

- Don't worry about it. - It's on its way.

Your daughter is with Dr. Bynum.

I'm confident that she'll be able

to gain the weight for surgery. I don't understand.

You don't need to understand.

You need to say, "Thank you," and you need to get out now.

Thank you.

I-I still don't follow. Who's bringing the vector here?

He came to me, too.

James Moriarty.

I killed my father.

He shoved my sister off a balcony

and left her a paraplegic.

And I killed him before he could finish the job.

Moriarty knows.

He gave me a job to do here.

I ruined the vector.

I didn't know why he wanted me to do it,

but I took the chemicals he gave me

and I tainted the AAV.

The reason Stephens is barely alive...

...the reason he might have brain damage already...

...it's me.

Ingrid came to see me last night.

She decided who she wants to be.

Dr. Derian went to see Moriarty this morning.

She came to see me before she set it up.

She told me everything.

Now Moriarty's coming here.

Why on earth would he do that?

Sir, are you all right?

He came here last week.

Pretended to be a patient.

I saw him in the exam room.

He gave me these.

He also gave me

one of his cuticles without realizing it.

He knows we have his DNA.

He set the meeting for the incline.

I arrived two hours earlier

and covered every surface in both cars

with something Watson cooked up.

Something pointed right at his genome.

Moriarty's coming because he's sick.

He knows that I'm the one that made him that way.

He knows that I'm the only person on the planet...

...that can keep him alive.

What did you do to me? I can't see.

"Always & Everywhere."

It's a good name.

It's very you.

I targeted your mitochondrial DNA.

Caused a point mutation

by changing a single letter in your genome.

G to A.

You can barely see now, but... you'll be completely blind soon.

After that, spasticity, cardiac arrhythmia,

encephalopathy,

then you'll die.

I offered her everything.

Dr. Derian doesn't want what you have to offer.

Do you want me to cure you?

You're a brilliant man.

If you want what I can give you,

then I'd imagine you brought what I need.

I won't go under general anesthesia.

You'd never let me wake up.

Well, I'm not sure if you've looked around.

Probably not since you're half blind, but...

you're not in a position to negotiate.

There's no need for a general.

I'll put a local anesthetic into your eyes.

You'll have a series of injections.

You should be better in about a week.

What happens then?

I don't know, I'd imagine that's up to you

and whatever lawyers you hire.

Me? I'm just a doctor.

I keep things simple.

And this...

is as simple as it gets.

James Moriarty.

Do you want to die today?

He wants the cure.

He brought what we needed.

I'm gonna give it to him just like we talked about.

But I need to hear from everyone first.

No one can opt out.

Do it.

I-I'm with you. Oh, yeah.

This is Stephens.

It's the only way.

Book the OR for Stephens.

You look terrible.

You don't have brain damage.

That's good.

Stephens, I'm sorry.

I should've never dated Lauren.

Doesn't matter that you broke up with her.

It was selfish.

And blind and, um...

...me.

We fell in love, though.

It's real. I-I can't just stop.

I can't stop it because of how it started.

I know.

I'm happy for you.

I'm happy for her.

I am going to rip the hell out of you

when I give my best man speech.

My head...

really, really hurts,

and I'm already thinking about one-liners.

I kissed you.

When you were sick.

Thanks. Mm.

Don't be too grateful.

Seemed like it might've killed you.

See, it's hard to evaluate that statement

because I don't remember.

Oh.

Well... Hmm.

Well, I can help with that.

You have to see him, you know.

You can't avoid it anymore.

I know you're sorry.

And I know that you don't know how to say that.

I appreciate what you did.

I stayed sick because of you,

but I also live because of you.

Thank you.

But I can't work with you anymore.

You have to go.

Can you see me?

I, um...

once knew a man named Sherlock Holmes.

He was my best friend.

He made the world a better place every single day he was alive.

You killed him.

I have twin doctors working at my clinic.

They're amazing doctors.

They're growing into the very best versions of themselves.

You tried to kill them both.

You forced Shinwell to change my medications.

I treated patients

under the influence of a hallucinogen.

What was the idea there?

Create a-a record of erratic behavior

so you can get rid of me?

Sick people come to see me from all over the world.

They trust me to take care of them,

and they leave the secrets of their DNA in my clinic.

You turned their genes into a tool

to murder anybody that you wanted to.

Well...

...as your doctor, I...

have to tell you that the cure didn't work as well as I hoped.

No, you see, y-your scans, they're highly concerning.

I'm worried that you may have a stroke

in the very near future.

What did you do to me?

Well, you can see.

The other changes that we set in motion,

well, it turns out there just wasn't much we could do.

You took an oath.

I did.

"First, do no harm."

You are the harm, James Moriarty.

I treated you, but for the good of the world,

I am glad you are not gonna be walking out of here.

No, yeah, well,

I did give you your eyesight.

But all that really means is that

I am the last thing you will ever see.

When?

Maybe soon.

Maybe now.

But I'm gonna sit with you.

I owe you that.

Who are you?

What made you this way?

So you're gonna die with your secrets, huh?

What else do I have left?

He's gone.

I'll take it from here.

I got you.

I like her.

You didn't ask, and you don't need my permission

or even my opinion, but I like her.

Thank you.

You gonna come eat?

Seriously.

I am violating many, many rules

by cooking for you on the third date.

I mean, I don't even tell a man I know how to cook

until certain requirements have been satisfied.

Lucky me.

Don't say that until you try the gumbo.

I'll be there in a minute.

Okay.