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Original subtitles

The human body contains about 37 trillion cells.

Each type of cell has its own role.

For example, red blood cells are responsible for transporting oxygen.

White blood cells fight off harmful substances that enter the body.

These cells work together with each other, every day, without stopping

which allows us, humans, to survive.

This is the Red Bone Marrow.

The place where blood cells are born and spend their childhood.

(RED BONE MARROW) ‎

(RED BONE MARROW) This is the hometown for blood cells.

Here, blood cells are born from Hematopoietic Stem Cells

and selected according to their type.

Here, Red Blood Cells are born as precursor cells

will grow into cells called erythroblasts

and are educated by Macrophages.

Here you go.

Thank you.

Ms. Macrophage?

You...

Why are you here alone?

I love bullying small Red Blood Cells!

(Streptococcus pyogenes, BACTERIA) I love bullying small Red Blood Cells!

Threat detected!

A small White Blood Cell is trying to kill me?

I will protect you.

I will become a great White Blood Cell!

Big bro!

I hate these useless little cells!

It's okay now.

Thank goodness.

Mom was so worried.

Ms. Macrophage, I'm being bullied.

Don't cry.

Let's go back.

(ENUCLEATION CEREMONY) Congratulations on your graduation.

From today onwards, you will become Red Blood Cells

that receive oxygen in the lungs

and circulate it throughout the body.

Congratulations on your enucleation.

Don't get lost and succeed in your mission.

Yes! I swear to become a great Red Blood Cell.

Papa, time to wake up.

Oh geez.

Papa, wake up!

Papa, come on...

Wake up quickly!

Yuck.

Wake up! Wake up...

Thanks for the meal!

What is this?

Oh, tofu scramble. A healthy and low-calorie dish.

Why does it have to be a healthy menu? It's usually just an omelet.

Blood pressure, blood sugar, uric acid, cholesterol.

The results are out. There's no point in hiding them.

"Re-examination required. You need to improve your diet."

I feel responsible.

Then what is this "Fecal occult blood test: Positive"? Isn't this bad?

It's nothing. Just hemorrhoids.

Not funny at all.

- Get it checked at the hospital again. - Okay, okay.

I'm off.

Delivering carbon dioxide to the lungs,

receiving oxygen, then circulating it to the cells throughout the body.

I can do it.

I definitely can.

Let's go.

- Ah, get out of the way! - Ah, sorry.

There it is! A large blood vessel.

Hey, this is a one-way street.

Sorry.

What? Wrong way?

Attack!

(Staphylococcus aureus,BACTERIA) From now on, this place is ours.

I will kill anyone who gets in my way.

I will protect you.

So this is where you were?

What a delicious-looking little one. I could just eat you up.

This is a Neutrophil Division White Blood Cell, number U-1146.

The attacking bacteria have been successfully eradicated.

Big Bro!

Thank you for your help.

When I grow up, I will definitely become a great Red Blood Cell.

I promise.

- Hey, what are you looking at? - Nothing.

Thank you for your help.

I'm just doing my job.

Oh, I mean... you're welcome.

Yes!

Kill! I'm gonna kill them no matter what!

- Scary, scary, scary. - He's cool.

He's different, huh?

Helper T Cell reporting.

We received a report that Pneumococcus have successfully entered the bloodstream.

Therefore, we are deploying Killer T Cells.

Helper T cells and Killer T cells.

Helper T Cell.

When I, Macrophage, inform that a virus or bacteria has entered the body,

they formulate an attack strategy and deploy Killer T Cells to fight.

Killer T Cell.

They will directly attack and destroy cells infected with bacteria or viruses.

They are reliable cells.

Don't be slow!

Yes, sir!

Hey, listen up!

If you see them, kill them within two seconds.

Cowards who let them escape will be sent to the spleen and never return!

Yes, sir!

They are Killer T Cells.

This is bad! If I don't kill them soon, they will divide.

What?

Be careful!

The pneumococcus's target is Red Blood Cells carrying nutrients.

So I'm about to head toward the ashes now.

Pneumococcus.

They will attack vital organs, then destroy this body.

Destroy? Wait. Don't leave me behind, please!

Lungs:

Organs that play a role in taking oxygen from the air into the body

and releasing carbon dioxide into the air.

We're here. These are the lungs.

Wow, it's so vast, isn't it.

My receptors are responding.

What's that?

A germ-detecting radar.

He's around here.

Where is it?

I'll kill him!

Couldn't the design be better?

He must be around here, I'll continue patrolling.

Okay, I'll continue taking the oxygen.

That's the direction of the bronchi.

Sorry.

You clumsy fool.

I've finally made it.

Alveolus:

The place where the exchange of oxygen

and carbon dioxide occurs between air and capillaries.

Alright, it's gas exchange time.

Huh?

(Streptococcus pneumoniae, BACTERIA)

Thank you.

For bringing me here.

This place is perfect for ambushing Red Blood Cells.

First of all, I will devour...

...you!

White Blood Cell?

As soon as I got away from you, the receptors stopped responding.

I was hesitant at first. But, it turns out he was hiding in your cargo.

How did you get here?

You need to learn more.

We, White Blood Cells, use diapedesis to pass through blood vessel walls and reach the enemy.

I won't let myself be killed after coming this far!

Let's run.

Wait!

Don't run away from me! You coward.

Red Blood Cell, take cover behind me.

Okay.

What's wrong, White Blood Cell?

It's just the three of us.

This is the end for you!

Die!

Not for us — only for you!

Hey, what's going on?

Bacteria successfully captured.

Bacterial eradication begins.

What's going on?

Alright.

What else?

What?

Hey, what's going on? Let me out!

It's useless.

That capsule can't be destroyed from the inside.

You’re in the killing machine from the lungs now...

Do you understand what that means?

Too much talk! Get me out.

Where are you going? Get me out!

You want a drink too?

Yes.

Put me down.

What is this?

Where is it being taken?

I told you. This is the killing machine.

Where are you taking me? Put me down!

Hey, stop!

Sneeze?

Countdown started.

Three, two, one, zero.

What's going on?

Hey, stop it! Hey!

Bye-bye, bacterium.

CELLS AT WORK!

Arata-senpai.

Good morning.

Oh, good morning, Niko.

Good morning.

- Math, huh? - Yes.

- Good luck. - Okay.

Bye.

Emergency alert!

Adrenaline rising!

Control failure!

Dopamine and endorphins, time to explode!

Let's get excited

and increase it!

We've lost control!

Adrenaline!

Let's add more! Great!

We've lost control!!!

Are you hurt, Niko?

I'm okay.

That must hurt.

White Blood Cell!

Hey, we meet again.

What's going on?

As you can see.

There was an impact that destroyed the blood vessel's outer wall

and causing blood to flow out.

In other words, it's a wound.

A wound?

If we fall into this wound, then it's over.

We won't be able to return to this world again.

Isn't that bad?

That's not all.

If it's not closed immediately, enemies from outside will enter.

We have to do something.

But, don't worry.

The workers who will fix this will be here soon.

Look over there.

Those little cells...

Slowly...

Be careful, there are stairs.

We've been waiting for you, Platelets.

Thank you for your cooperation!

Platelets.

One of the cell components found in blood.

When blood vessels are damaged, they gather to close the wound and stop the bleeding.

Everyone, ready?

Yes!

Then, does everyone have fibrin?

Of course!

- Alright, let's go! - Let's go!

- Excuse me. - Oh, sorry.

Alright. Now, we will connect fibrin with coagulation factors.

Yes!

- Don't fall, okay? - Yes!

Let's do it. One, two...

Blood clotting:

When proteins called coagulation factors start working,

a fibrin network is formed,

wrapping and strengthening the blood clot formed by the Platelets completely.

Blood clot is done!

Done!

Amazing.

Right, White Blood Cell?

White Blood Cell?

Next, Older Brothers, please help.

Okay.

White Blood Cell?

White Blood Cell?

Are you okay?

Older Sister too!

Sorry.

Are we stuck?

When a hole forms in the vessel wall,

as blood cells, we will cover the hole with our bodies

until the cells that become the outer wall are repaired.

This is Factor II in coagulation.

What? How long will we be like this?

I don't know. We wait until it dries and becomes a scab.

Boss, thank you for yesterday.

What is that? Did your daughter prepare a lunch box?

She said it's healthy food, and she reduced the portion.

Your daughter is so kind. My child won't even listen to me.

Oh, it's cooked.

Is that yours too?

We can't work if we only eat a little.

Even though Niko made it with balanced nutrition.

Boss, what about tonight?

We just went yesterday! He loves it, right, Shige?

You drink almost every day, right?

Carbon monoxide warning!

Toxic substances detected in the blood vessels.

All response units, please be careful when moving!

Acute fatigue, lack of sleep, overeating.

This body is under too much stress.

Even oxygen deficiency.

Don't give up. Keep circulating oxygen!

Fight, cells!

Arrest in the aorta!

(SEVEN BACTERIA)

(IF YOU'RE GONNA PITY ME, HAND OVER SOME OXYGEN!)

Red Blood Cell, your oxygen supply has been low lately.

Sorry, the superiors ordered me to prioritize vital organs first.

What if the peripheral cells eventually die?

Sorry, I can't do anything. These are the superior's orders.

Let's go!

Wait! I'm not finished talking.

Stop apologizing.

Complaints never stop, newbie. Don’t waste your time.

Okay.

Hey, Red Blood Cell! Deliver the oxygen quickly!

Sorry, I will quickly deliver it.

It's because of you. I'm starting to pick up your bad habits.

I'm sorry.

Oh! That was close.

What is this road?

LDL cholesterol?

They are the cholesterol transporters.

If this continues, the risk of arteriosclerosis will increase.

Come here!

What's going on?

Don't worry.

It's just alcohol.

Alcohol?

Ah, great. It's seeping into my body!

I'll have liver and chives, and… some pig stomach.

This is bad. Let's get out of here quickly.

If this continues, we will carry alcohol throughout the body.

That's right, it really tastes like alcohol.

I feel dizzy.

Come here. I'll show you how to get rid of it.

Liver:

An organ that functions like the body's chemical factory,

playing important roles such as substance synthesis, secretion, and detoxification.

A bad day, huh.

Come on, drink up.

What is this?

Alcohol decomposer.

That's ADH.

This is ADH? (Antidiuretic hormone)

To help the body regain consciousness,

the alcohol in the blood will be broken down and eliminated.

(Hepatocytes) That's the job of the Hepatocytes.

What's wrong?

I went through a lot to get you here. Have a little fun.

Do I have to help you drink it too?

Is this body okay?

The blood vessels are blocked, and I can barely get through.

The superiors only care about the oxygen supply target. They don't think about us at all.

This work environment needs to be improved immediately!

It's time.

When our lifespan is over, Kupffer cells will consume us for nutrients.

This is our real life.

All we do is transport oxygen until we die.

But, it's okay.

If something happens, I'll help you!

Even if we work hard, we'll still end up like that.

I don't want to!

Newbie!

No wonder.

As long as this body doesn't change, our work environment will remain the same.

It will remain bleak forever.

Who is responsible?

Thank you for today.

If you don't mind, would you like to hang out sometime?

No, no, no. It's too sudden to ask him out.

No, no, no.

Oh, I sent it.

It's over.

Okay.

Okay?

Thank you!

When?

How about Sunday?

Roger!

Yay, Arata is being nice to me!

It's warm.

It's not here.

I'm lost again.

When I grow up, I'm definitely going to be a great Red Blood Cell.

I promise.

Let's go.

Excuse me, I want to go to the kidneys...

Your movements are too wide.

That's enough!

How is it? White Blood Cells who work directly are much stronger.

You guys should also do your best.

Yes.

Damn it!

You're pretty energetic, right?

I...

When I grow up, I'll definitely become a White Blood Cell as great as big bro.

I'll be waiting for you.

Thank you, big bro.

You haven't changed at all since you were little.

This is Macrophage. Type B influenza viruses have entered the body.

Roger that.

We will deploy Killer T Cells.

Recently, the virus has been spreading rapidly.

Don't let your guard down!

Yes, sir!

Killer T Cells, are you here to help us?

Since we're here, you can rest easy.

Just be quiet. Let's go!

Let's go!

You're slow.

What do you mean, you bastard?

How dare you steal our job!

Stop it.

(NK Cell)

Stop acting so tough.

(NK Cell) Besides, you can't work without instructions from Helper T Cells.

You little toy soldiers.

What did you say?!

You can only fight in groups, right?

That's why I'm the only one who can move freely throughout the body alone.

I was destined to be a killer.

Natural Killer. I am an NK Cell.

What's so natural about it?

You're still as selfish as ever!

Say that again.

This is not the time to fight. Look.

They're coming.

Get out of the way.

I can handle this myself.

I won't let you steal our hard work. Let's go, everyone, charge!

Red Blood Cell, get away.

Okay.

- Let's go! - Yes, sir!

Don't come near!

Sorry.

So, there's a place like this. That's new to me.

This is the nasal cavity.

As much as one liter of fluid is produced every day.

This is what's called snot,

which helps clean dust, mold, and viruses.

It's so warm.

What's wrong?

You've just been brooding since earlier.

I'm so envious of you guys.

You have various roles,

fighting enemies to protect this body,

and that's so cool.

As for me,

I can only circulate oxygen.

I always get lost.

Even though I swore I'd become a great Red Blood Cell.

That's not a problem.

We, White Blood Cells, patrol to find threats.

Macrophages provide info about the enemy.

Then, Helper T Cells can give orders,

and Killer T Cells are deployed.

Together we defeat the enemy.

We all carry out our duties with pride.

Including you too.

We can keep fighting

because you, Red Blood Cells, keep circulating oxygen for everyone.

We all are cells...

...that work in the same body.

So that means...

...you're doing a great job.

Thank you very much.

Not at all,

we did it together.

Good morning, Arata.

Morning.

Sorry to keep you waiting.

It's okay. Let's go.

Let's go.

Are you really okay?

I heard you had the flu.

I'm really okay.

I feel very healthy.

That's good.

Yeah!

First date!

Love is in the air!

Bang, fly, fly higher!

Thank you.

The corn is delicious.

Your daughter is on a date, right? You must have mixed feelings.

As long as he's not a weirdo, it's okay.

I'm off, Boss.

Cheap food won't do.

- Here, for snacks. - Thank you, Boss.

Have a good day.

Yeah, more jumps! Go! Go! Go!

The Lovey-dovey couple are happy and soaking wet.

Let’s get the party going, everyone!

How beautiful...

Sparkling...

It's been a while since I've been here.

Really?

Yes.

Back then, during school holidays,

my mom often took me here

because I really liked aquariums.

It's a shame we didn't go with her.

I come here alone when I feel like it.

My mom passed away...

...when I was nine years old, due to illness.

I see.

Oh, is that why you want to study medicine?

Yes.

Oh, this scarf...

...was knitted by my mom for me when she was in the hospital.

But, she stopped halfway.

Look at this.

The stitches are rough in the middle and not right at all.

My Dad was determined to finish Mama's gift.

So, he finished the rest.

That's why I like it.

You're stronger than I thought.

Ah, not really.

♪ I won’t lose! ♪

♪ I won’t give in! ♪

♪ With a will this strong, no one can bring me down... ♪

Ouch.

(ANUS) ‎

(ANUS) Listen, don't underestimate ourselves.

We are the strongest muscles there are.

Keep tightening until the cerebrum gives the order.

Don't let it loosen!

Don't let those inner muscles affect us!

(INNER ANUS) Don't let those inner muscles affect us!

(OUTER ANUS) We are the ones guarding this place.

(OUTER ANUS) Be proud!

Don't be careless even for a moment.

Don't let the feces come out!

Use all your strength to tighten it.

Excuse me!

I've come to deliver oxygen.

- Excuse me! - Just put it here.

This is a dangerous zone.

Newbie, I don't want to lose you.

I had a bad experience when I first came here.

We came at the wrong time. Then, many of my colleagues...

Senior, are you okay?

Now it's time for gas exchange. Let's go.

Damn, why again when I'm here?

Newbie, this is bad.

Emergency alert.

Discharge will begin soon.

Discharge?

Make way!

It's feces.

They're going to release the poop.

Poop?!

Make way...

Hold on!

Hold on!

If we stay here, we'll be affected.

Let's run!

Warning, warning. Emergency bowel movement procedure initiated.

Everyone, fall back!

Damn. Let's get out of here, Newbie!

What's going on?

Time to run!

They got the cerebrum order.

Senior.

Don't go out yet.

Right.

I won’t give in.

No way.

Don't let even a single particle escape!!!

Please.

Please...

Damn. This is crazy. What did he eat to make his body so weak?

Try harder!

They're coming out!

What's going on? Didn't the cerebrum forbid it from coming out?

How would I know it would become like this?

Quickly, let them out!

Why did it stop?

They don't understand the orders from the cerebrum.

When feces reach the rectum, all that happens is a natural urge to expel it.

This is a struggle.

This is bad.

At this rate, they'll break through.

If we don't hold on, we'll be carried out too.

Push it in!

(Heisei era’s Hemorrhoid — That’s all, folks▼) ‎

(Heisei era’s Hemorrhoid — That’s all, folks▼) What...

Is the feces leaking?

No, the hemorrhoids burst.

Burst?

It hurts...

This body is so bad that it's making us suffer.

Please...

I'm going to die.

I can't take it anymore.

Strengthen yourself!

Newbie!

The disposal begins!

The disposal begins!

Everyone, make way!

- Newbie. - Senior.

Are you okay?

Newbie.

Yes.

I promised, right?

If something happens, I will help you.

Senior.

Let's get out of here.

Let's bring the next oxygen!

Come with me.

Let's go.

This is bad.

There's a second wave!

Make way again!

Senior, don't let go!

Don't let go!

- I know! - Yes. Don't let go!

I...

...will always be with you!

Forever!

Senior!

Newbie!

Finally...

Ah, thank you for today.

You're welcome.

Arata.

I...

...really had fun.

Thank you so much, Arata.

Then, see you tomorrow.

Niko!

Actually...

I like you!

Yes!

I feel the same way.

Really?!

Thank you.

I'm so happy.

Thank you.

Let’s be good to each other.

Excuse me for a minute.

Hello.

What?

Papa!

What's wrong?

Your boss said that you fainted.

Oh, you scared me.

When I went to the toilet, I felt dizzy and seemed to faint immediately.

I was scolded by the doctor because he said this was due to an irregular lifestyle.

So, you didn't go to the hospital before?

Yes, that's right.

Stop joking about a serious matter.

Think about your own body.

Oh, okay.

Are you Niko's boyfriend?

Are you okay?

Take this.

It looks like this fell from your father's truck.

Apparently your father always brags about his daughter at work.

"Unlike me who failed, she is smart and aspires to be a doctor."

"I want to add more work because my daughter will go to college in the future."

"So, I asked Mr. Boss for more work."

"That's why I'm still working, even though today is my day off."

Come here.

It's been 14 days since you were born as blood cells,

your peers have developed into myelocytes.

However, you are still at the promyelocyte stage without any development.

What?

If this continues, the ability to differentiate will be lost.

Abnormal blood cells like you

will multiply quickly and uncontrollably.

So, the ability to form healthy blood will be disrupted.

What? We are not normal?

Sorry, but you are not needed in this body and will be destroyed.

That's impossible.

Take him.

All right!

Don't do this! Stop!

You too.

Let go of me!

We will become White Blood Cells and work!

Catch him!

That's enough.

Get out quickly.

Why?

Why me?

Why?

Answer me!

What is that?

(ONE MONTH LATER)

Thank you for the food.

Oh, no. I'm late.

Hey, could you start making less rice now?

I did a blood test yesterday at the hospital,

and all the results improved.

It must be thanks to your cooking.

Okay, I understand. I will reduce the portion.

Yes.

Alright, Papa's lunch is ready. Please wash the dishes, okay?

Okay.

What's wrong with your leg?

I don't know. It seems like I bumped into something.

I'm leaving now.

Yes.

Sorry for the wait. Here's the oxygen.

Please stamp here.

You're always on time. Thank you.

This is my job. I will deliver it again.

Please.

Okay.

Hooray! Finally, I can wander around without getting lost.

She's developing rapidly.

White Blood Cell?

Are you okay? Sorry.

It's okay. I was just walking aimlessly.

Platelets.

Ah, brother, sister!

Did you see my friends?

I didn't see them.

What about you?

Me neither.

What's wrong?

Because we're separated, the bruises won't heal.

It's difficult for us.

I see.

What's happening?

Could it be that they're lost?

Are you alone?

Yes.

Strange...

The number of White Blood Cells have been decreasing lately.

Niko!

Good morning, senpai.

Are you okay?

Niko, what's wrong?

Niko, are you sick?

What?

Regarding the future treatment plan,

we will inform you after the details of the results are out.

Currently, the number of platelets in her body is very low

and prone to bleeding.

In order to continue treatment,

she needs to have a blood transfusion immediately.

Sir?

Are you okay, Sir?

Yes.

It's all thanks to her.

Thanks to Niko, I, who used to be sickly, am now healthier.

Niko must also be healthy!

Doctor.

I will do anything to help.

Therefore, please heal Niko.

I beg you.

I beg you.

Leukemia?

Yes.

Acute myeloid leukemia, to be exact.

In our blood,

there are red blood cells, white blood cells, and platelets, right?

Among the three, the ones that become malignant are increasing.

What will happen to me?

That...

If left untreated,

the number of healthy blood cells will decrease and that's not good.

So, because of that...

you have to undergo chemotherapy.

With anti-cancer agent.

Yes. But...

Everything will be alright.

I promise.

Why...

Why not with me?

Why with Niko?

Why...?

Why?

Why is it so difficult?

You're so careless, Honey.

You're so blabby. That's why you should get well soon.

I'm back!

Does Mama know? I got chosen to be on the sports event committee.

Really, Honey? Congratulations.

Great, right?

Yes, that's amazing.

Mrs. Urushizaki, are you conscious?

Yuko. Wake up, Yuko.

Mama! Mama!

- Prepare the vasopressor. - Yes.

Yuko!

Mama!

Let's donate blood! Let's help each other.

Look, the road has been repaired neatly.

Yes, it's easier to do our work now.

What is that?

Hey, this will help you get better!

Please help me.

Okay, I'm coming.

Please help me too.

Here.

Me too.

Excuse me.

- The oxygen. - Here.

Leukemia cells are growing rapidly in the body!

Please be careful!

Reinforcements have arrived!

Thank you very much.

Red Blood Cell, is everything okay?

We're okay.

We will definitely circulate oxygen.

I'm counting on you.

Attention everyone. Did you bring oxygen?

Yes.

What exactly is happening?

Wait, I'll tell you after I circulate it.

Oxygen has arrived.

Listen, be careful!

We don't know where the Leukemia cells are hiding.

Don't let your guard down!

Yes, sir!

How stupid.

If you talk too much, the enemy will run away.

You insolent brat.

Shut up.

You can only fight with your buddies.

You spineless coward.

How dare you!

Be quiet.

Someone's coming.

Long time no see.

Brother.

I...

When I grow up, I'll definitely become a White Blood Cell as great as big bro.

You are that little cell from back then?

I'll be waiting for you.

Thank you, big bro.

Hey, weren't you waiting for me?

Brother, fight with me again.

Look, I'm much stronger.

Bastard.

I'll take care of him.

Fight me!

Huh?

Why you?

I was talking to him.

It was reported that Leukemia Cells are growing rapidly in the body.

They are invading the lung and spleen regions,

and appear to be spreading to other organs as well.

Deploying Killer T Cells.

It's useless.

We will continue to multiply.

Kill, kill, kill, kill them all!

Enough, stop it.

There's no way this body can survive with such abnormal cells.

Why?

Why would you say something like that?

You were waiting for me, right?

Let's fight together.

Look, I'm much stronger.

I'm sorry.

But, that's the reality.

Do you also think I'm abnormal?

In that case, I'll kill you.

It was reported that Leukemia Cells are also growing rapidly in the red bone marrow.

Please head there immediately!

This is bad.

Blood cells are being produced in the red bone marrow.

If that place is taken over, new blood cells can't appear.

Let's go there.

Next, we have to circulate oxygen to the small and large intestines.

Wait a moment.

Shouldn't we rest first?

There's no time to rest.

We have to circulate it to the weak cells.

What the heck? What happened?

So that's why.

It certainly destroyed the Leukemia Cells,

but at the same time it also killed a large number of normal cells.

Chemotherapy?

Watch out!

NK Cell!

I'm okay!

Hey. Look at that!

I don't understand.

The missiles don't seem to work on them.

Damn! Where are they coming from?

Are you okay?

Please get me some water.

Okay.

Sorry...

I'm sorry.

Why? You don't have to apologize.

Sorry.

Are you thirsty?

Excuse me...

NK Cell!

Are you hurt?

They're appearing again. At this rate, it's impossible.

We're running out of oxygen.

What are the Red Blood Cells doing?

At this rate, we're all going to die.

Red Blood Cells will definitely come.

They will definitely deliver oxygen to us.

Hey, can we still win?

Being afraid is not your normal self.

If we give up now, this body will be gone.

Leave this to me! You guys go find the Red Blood Cells!

NK Cell, don't push yourself!

I don't need help.

I can fight on my own!

You're so narcissist.

So, only you can show off?

I'll fight too.

Captain!

White Blood Cell!

We'll hold them back.

You go find the Red Blood Cells!

Attack!

Yes, sir!

White Blood Cell, now's the time!

We'll hold them back! Hurry back!

What's wrong?

This is impossible now.

No matter how hard we try,

will it really change this situation?

Look around you.

There are no more Red Blood Cells besides us!

At this rate, the oxygen supply won't be enough.

This body can't last any longer!

I'm scared.

I want to end this suffering.

Me too.

I'm scared too!

So scared!

But now...

...all the cells are fighting desperately to protect this body.

That's why I won't give up.

No matter what happens,

I will circulate oxygen to the cells that are fighting!

Because that's my job.

For a long time now, she has been thoughtful.

When her mother died,

I was the one being comforted by her.

Look at this.

(PAPA, BE CHEERFUL! — NIKO)

I'm such a terrible father, aren't I...?

I'm so pathetic.

Because I am powerless...

...could you please accompany and encourage her.

I beg you.

Yes.

Of course.

Sir! Your daughter!

Are you alright?

Her blood pressure is dropping.

Stop the chemotherapy and set the IV drip to full speed.

Niko!

Put 5 liters on her oxygen mask.

Yes.

Prepare the vasopressor.

Yes.

Niko, can you hear me?

NK Cell!

Can you hear me?

Excuse me.

Starting with five liters of oxygen.

Can you hear me?

Hold on!

Killer T Cell.

That was fun, right?

Teaming up with others once in a while isn’t too bad.

Damn it!

This isn't over!

Actually,

I was very jealous of you.

I was jealous of you fighting freely without orders!

That's what I like about you!

Bastard!

Found you!

I'm counting on you.

White Blood Cell.

Leukemia Cells are also appearing in the pancreas area.

Also the large and small intestine areas.

Killer T Cell, go to the area now!

Killer T Cell?

Finish them off!

Finish them off!

They're...

...already here.

We can keep fighting

because you, Red Blood Cells keep circulating oxygen for everyone.

I'm counting on you.

I have to deliver it.

Miraculously, she's still holding on to this moment.

But, I can't be sure how long she'll last.

So, what can we do?

The only option left is a bone marrow transplant.

If the donor is found, we will start radiotherapy.

Radiotherapy?

A procedure before the transplant is performed,

where all the cells in the blood are now destroyed,

so that the newly transplanted bone marrow

is not considered a foreign object and gets attacked.

Come here!

The oxygen is here!

Why are you still here?

Quickly deliver oxygen to them!

Watch out!

Ms. Macrophage?

Long time no see.

How is it possible?

Didn't I tell you?

Being a teacher is just one of my many faces.

I’m also an assassin.

You should leave quickly.

You have a mission to carry out.

Okay.

Come on.

No.

I’ll stay and support Ms. Macrophage by supplying oxygen.

I’ll be fine.

No matter what happens, I’ll deliver the oxygen.

Because that is my job.

Oxygen here!

White Blood Cell?

White Blood Cell!

Red Blood Cell...

I came to give you oxygen.

Sorry, I'm late.

Thank you, Red Blood Cell.

Not at all.

The radiotherapy procedure begins now.

Help me!

Anyone!

Save me!

What is that light?

What exactly is happening?

And why even our colleagues...?

I don't know.

Anyway, if the number of my colleagues decreases again,

I won't be able to protect this body.

Red Blood Cell.

In our place of origin, the Red Bone Marrow,

the Hematopoietic Stem Cells that give rise to us must still be working to this day.

You need to deliver oxygen

to those Hematopoietic Stem Cells.

We need them to produce more blood cells.

But in this situation...

...I don’t even know if I can make it.

Relax.

I will always protect you.

Come on.

Let's go faster.

A little more.

Yes.

Hey... I’m starving.

How about you give me that oxygen?

No.

I won't give it to you.

Oh, okay.

Then you have to die.

White Blood Cell!

Red Blood Cell, continue your journey.

But...

Hurry up.

Do your job.

Alright.

Big bro.

Forgive me...

...but I have to kill you.

I see.

So even you, big brother, treat me like I'm something defective too.

Fine then.

Go ahead and kill me.

Why?

Everyone treats me like garbage.

Why?

Why should I...

...have to be destroyed?

I didn’t do anything wrong, did I?

I was just born… That’s all.

I just wanted to be a cool and worthy White Blood Cell!

So, big brother...

how does it feel to be killed by a failed creature like me?

Painful, isn't it?

It must be painful, right?

Tell me.

Tell me I'm stronger.

What, it’s over already?

Lame.

- Thank you. - Please take it from here.

Are you okay?

Because right now there are almost no cells in her bone marrow,

we can't let our guard down for a moment.

Doctor...

is there anything I can help you with?

Please stay by her side, so that Niko's body can endure

until the time of the transplant arrives.

(THINGS PAPA LOVES)

(BUT WHAT PAPA HAS ALWAYS LOVED THE MOST IS...)

(NIKO'S SMILE)

(NIKO'S CHEERFUL, EVERYDAY SMILE IT'S PAPA'S FAVORITE THING IN THE WORLD)

(HE SAID HE LOVES THAT TOO)

(DO YOU KNOW LAUGHING CAN INCREASE THE BODY'S IMMUNITY?)

(ALMOST THERE! YOU CAN DO IT, NIKO!)

Thank you.

Thank you.

Why?

Did you come here to increase your troops?

Too bad.

It's useless.

There's no one left who can help you.

Aren't we partners born from the same world?

Why do we have to hurt each other?

We are not partners.

You were the ones who rejected me first, remember?

Because of that, I will change this world.

Into a fun world without rejection

where we can live freely.

I won't let that happen.

I swear.

Interesting.

But you're just a Red Blood Cell.

Die, you weakling!

White Blood Cell!

You need to learn a lot.

I can penetrate the walls of blood vessels

and go straight to the enemy.

Why?

Why?

I just wanted to be part of this body…

...and work together with everyone.

I...

...can't save you.

There's nothing I can do...

...to help or save you.

I will kill you.

Because that is my duty.

I thought so...

Big bro...

...is stronger.

I'm sorry.

When I grow up, I'll definitely become a White Blood Cell as great as big bro.

This body is in critical condition.

To all cells, please prioritize protecting life.

What will happen?

Are you okay?

I still have oxygen.

Here.

I'm fine.

There are other cells...

...that need much more oxygen.

But...

To continue protecting this body...

...we need your strength, Red Blood Cell.

No matter what happens...

...keep circulating oxygen.

Promise me.

White Blood Cell...

Back in those days...

Red Blood Cell.

You're really great.

I'm counting on you.

Thank you.

I promise.

So, please...

...don't die yet.

I beg you!

White Blood Cell?

White Blood Cell!

White Blood Cell!

Thank you very much.

Oxygen...

Here's the oxygen. Please hold on.

Thank you.

Oxygen.

The bone marrow transplant procedure has begun.

Congratulations.

Your new hematopoietic stem cells have successfully attached, right?

That means your body is able to produce healthy blood cells.

- Right, Doctor? - Yes, that's right.

Doctor, thank you very much.

Not at all.

We were all able to get this far, thanks to Niko's continued fight.

If it weren't for the strength of Niko's cells,

your body would have given out before the transplant.

If you're looking for someone to thank,

thank your body for all it’s carried you through.

Thank you.

To: The Small and Cute Erythroblasts.

In the past, I was a Red Blood Cell working in this body.

I was really clumsy

and often got lost.

Unlike White Blood Cells that can fight viruses,

all I could do was deliver oxygen.

I was worried for a while.

But now...

I've come to know that I am an important part

that protects this body.

It's not about who is the greatest or the strongest.

Because we all can't live alone.

We must help each other to complement each other's shortcomings.

That's how...

...we all protect this body.

I really like working with my colleagues.

There are about 37 trillion cells working in this body.

Most of them will later

die either because of threats or because of age.

Their tasks will be passed on to new cells that will be born.

We are the Cells at Work!

My tasks now...

...will be passed on to you.

Keep circulating oxygen...

...to protect this body.

Sincerely: Senior Red Blood Cell.

Alright, everyone. Let's get started!

What are you doing? The next class will start soon.

Okay!

(ONE YEAR LATER — SPRING)

Papa, hurry up!

Don't be late!

I was torn on which necktie to wear!

This isn't Papa's acceptance ceremony!

Hey, this is med school we’re talking about!

You can’t afford to be underestimated! You gotta look sharp, really sharp!

If you don't hurry, we might be late.

I told you you didn't have to come.

Hey, it's fine!

Arata, you're practically family now!

Papa, isn't the tie a bit plain?

Really? Wait a minute.

- Just stop talking. - Sorry.

Caught a cold?

No, this is...

This. You dropped it.

Thank you, Sis.

You're welcome.

Emergency alert!

Cedar pollen allergens have entered

through the drainage near the eye mucous membranes!

Cedar pollen?!

Where?

Where is it?

I'll kill 'em!

I'm gonna kill them no matter what!

Hey, what are you looking at?

Nothing.

I feel like we've met somewhere before.

It's nearby!

This is a Neutrophil Division White Blood Cell, number U-8996.

Cedar pollen allergens have been found.

We will begin eradication.

White Blood Cell?

Will we meet again?

We work in the same body.

Of course we'll meet again.

See you again.

See ya.

Kill! I'm gonna kill them no matter what!

Okay, I should go too.

(Red Blood Cells They deliver it like an express service!)

(Job: Deliver oxygen to all the cells in the body. Also: Carry carbon dioxide back to the lungs.)

(Time to circulate the body: Less than 1 minute. Only 90 days left until the exam!!)

(White Blood Cells, or Neutrophils)

(Job: Eliminate foreign invaders —like bacteria and viruses— that have entered the body from the outside.)

(White Blood Cells: Neutrophils, Eosinophils, Macrophages)

(Receptors: Radar-like mechanisms that detect threats such as bacteria.)

(Killer T Cells)

(Job: A scary "hitman" that identifies and destroys foreign invaders like virus-infected cells and cancer cells.)

(They’re deployed under the command of Helper T Cells.)

(Are they friendly?)

(NK Cells)

(Job: They’re Natural born Killers with the power to eliminate invaders.)

(They don’t wait for orders. If they spot an enemy, they attack on instinct.)

(This Week’s Review Topic # Definitely ace the med school entrance exam!)

(Macrophages A type of white blood cell.)

(Job: They help red blood cell precursors, erythroblasts, to differentiate and mature.)

(They attack invaders like bacteria and report the threat to Helper T Cells.)

(Helper T Cells)

(Job: Receive alerts about invading enemies and deciding the strategy for attack.)

(They give the order for Killer T Cells to mobilize.)

(Today’s Summary:)

(Helper T Cells → give orders to Killer T Cells Macrophages → pass on antigen info → to Helper T Cells)

(Hepatocytes. These cells make up most of the liver.)

(Job: Handling metabolism and detoxification. It's known as the “chemical factory of the body,”)

(It contains around 2,000 types of enzymes.)

(Pneumococcus)

(A pathogenic bacterium that causes illnesses like pneumonia.)

(A highly toxic bacterium with a capsule.)

(Streptococcus)

(A type of resident bacteria found in areas like the pharynx, digestive tract, and skin.)

(Rarely, it can cause a severe infection known as necrotizing fasciitis, also called "flesh-eating disease.")

(Staphylococcus)

(A bacterium that normally resides on the skin and in hair follicles.)

(It is called "staphylococcus" because it looks like a bunch of grapes.)

(staphylē = 'bunch of grapes' coccus = 'spherical bacterium')

(Influenza Virus)

(The virus that causes the flu.)

(It is highly contagious and is said to multiply up to 1 million units within 24 hours.)

(Fever! That was rough)

(30 days left until the exam Health management is important!)

(Leukemia Cells)

(It's a type of blood cancer that undergoes genetic mutations as it grows, turning into cancerous cells.)

(Even in healthy individuals, around 5,000 cancer cells are produced daily.)

(Fortunately, the immune cells fight them off each time.)

[Bone Marrow Fluid (Hematopoietic Stem Cells)]

(Cells in the bone marrow that produce blood cells,)

(such as red blood cells, white blood cells, and platelets.)

[Nerve Cells (Neurons)]

(Nerve cells — also known as neurons — make up the brain.)

(The human brain contains a huge number of them.)

(Around 100 billion neurons!)

(External Anal Sphincter)

(It's a muscle that you can control voluntarily.)

(In contrast, the internal anal sphincter is a muscle that you cannot control voluntarily.)

(Burst hemorrhoid)

(Fecal Occult Blood Test: Positive)

(Platelets)

(A type of blood component that gathers at the site of blood vessel damage to seal the wound.)

(They make up less than 1% of total blood volume. A rare character!)

(End of the quiz section!)

(Cedar Pollen)

(Cedar pollen is the main cause of hay fever outbreaks in early spring.)

(Hay fever is an allergy triggered by the immune system overreacting to pollen.)

(Sneezing, runny nose, itchy eyes... you name it!)

(Sneezing)

(A reflex action that tries to expel foreign substances like dust or viruses from the body.)

(It can be triggered by allergic reactions or irritation of the nasal mucosa.)

(Photic Sneeze Reflex: Some people sneeze when they look at the sun!!)

Translated by: dreamingbleu

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