1 00:00:03,871 --> 00:00:05,973 ♪ ♪ 2 00:00:06,074 --> 00:00:08,509 YOUNG VOICE: To my classmates, faculty, 3 00:00:08,609 --> 00:00:11,345 and to our distinguished guests, 4 00:00:11,479 --> 00:00:14,582 my name is Taryn Quintyne. 5 00:00:14,682 --> 00:00:16,684 It is my honor to represent 6 00:00:16,784 --> 00:00:19,019 the class of 2016 7 00:00:19,120 --> 00:00:21,455 as our valedictorian. 8 00:00:22,790 --> 00:00:24,525 As your valedictorian. 9 00:00:24,658 --> 00:00:25,593 (coughs) 10 00:00:25,693 --> 00:00:27,795 Over the past four years, 11 00:00:27,861 --> 00:00:30,098 we made lifelong friends. 12 00:00:30,198 --> 00:00:32,866 We fell for our first boyfriend, 13 00:00:32,966 --> 00:00:35,469 our second boyfriend... 14 00:00:36,604 --> 00:00:38,806 hey, maybe even our third boyfriend. 15 00:00:38,872 --> 00:00:40,408 Excuse me. 16 00:00:40,508 --> 00:00:44,478 Most of you know about my challenge... (coughing) 17 00:00:45,846 --> 00:00:48,048 (clears throat) I call it 18 00:00:48,149 --> 00:00:50,184 "the bully." (coughing) 19 00:00:50,284 --> 00:00:53,053 Taryn, one to ten, how bad is it? 20 00:00:53,154 --> 00:00:55,489 Not today, please, not today! 21 00:00:55,556 --> 00:00:57,258 (coughing) Be honest with me, baby. 22 00:00:57,391 --> 00:00:59,193 One to ten? 23 00:00:59,293 --> 00:01:02,430 I'm calling, I'm calling. 24 00:01:02,530 --> 00:01:04,732 (coughing) 25 00:01:04,831 --> 00:01:06,967 ♪ ♪ 26 00:01:22,049 --> 00:01:24,418 ♪ 27 00:01:38,666 --> 00:01:40,868 DOCTOR: They can cure sickle cell now. 28 00:01:40,968 --> 00:01:42,603 What a world. 29 00:01:42,703 --> 00:01:46,374 The disease has been around forever, I guess. 30 00:01:46,440 --> 00:01:50,211 Someone figures out how to slice up DNA strands, 31 00:01:50,311 --> 00:01:53,814 change it and boom: Cure. 32 00:01:54,715 --> 00:01:57,017 We live in amazing times. 33 00:01:58,085 --> 00:02:00,554 Who are they curing, exactly? 34 00:02:01,955 --> 00:02:04,492 There are two versions on the market. 35 00:02:04,592 --> 00:02:07,561 One costs $3 million. 36 00:02:07,628 --> 00:02:10,231 The other's a bargain at two. 37 00:02:10,298 --> 00:02:13,367 Insurance covers exactly none of it. 38 00:02:14,168 --> 00:02:16,370 These things take time. 39 00:02:16,470 --> 00:02:18,339 They shouldn't, but they do. 40 00:02:18,472 --> 00:02:21,575 I'll let your hematologist know you're back again. 41 00:02:21,675 --> 00:02:22,976 We'll get you admitted. 42 00:02:23,076 --> 00:02:25,313 Get you a blood transfusion and send you home 43 00:02:25,413 --> 00:02:26,647 with some pain control. 44 00:02:26,747 --> 00:02:27,948 Hmm. 45 00:02:28,015 --> 00:02:30,150 Usual drill. Usual drill. 46 00:02:30,251 --> 00:02:33,120 NURSE (over P.A.): Code Blue in Room 3422. 47 00:02:33,187 --> 00:02:35,155 Code Blue in Room 3422. 48 00:02:35,289 --> 00:02:37,057 Th... 49 00:02:38,125 --> 00:02:40,293 The... 50 00:02:44,865 --> 00:02:47,968 SASHA: "The man with the glowing chest"? 51 00:02:48,067 --> 00:02:49,537 Is that a metaphor? 52 00:02:49,637 --> 00:02:51,505 Riddle, metaphor. 53 00:02:51,605 --> 00:02:55,108 Expression of Watson's unchecked vanity. 54 00:02:55,209 --> 00:02:56,777 I could puzzle it out, 55 00:02:56,844 --> 00:02:58,978 but that's exactly what Watson wants. 56 00:02:59,079 --> 00:03:00,548 (text sends) 57 00:03:04,852 --> 00:03:06,387 You want to talk about it? 58 00:03:06,520 --> 00:03:07,521 Talk about what? 59 00:03:07,655 --> 00:03:10,491 Honey, we've all written rage emails. 60 00:03:10,591 --> 00:03:12,226 SASHA: You hitting send on that? 61 00:03:12,326 --> 00:03:13,694 INGRID: I'm lead neurologist 62 00:03:13,794 --> 00:03:16,063 on this Spinal Signal Project. 63 00:03:16,196 --> 00:03:18,332 We're vetting candidates for the surgery, 64 00:03:18,399 --> 00:03:21,302 and the chairman keeps rejecting my suggestions. 65 00:03:21,402 --> 00:03:22,870 I'm lead neurologist. 66 00:03:22,970 --> 00:03:24,672 Is that an official title, or are you just 67 00:03:24,772 --> 00:03:26,807 the only neurologist? 68 00:03:26,874 --> 00:03:29,277 These people are going to have. 69 00:03:29,377 --> 00:03:31,912 AI implants in their brain and spinal cords. 70 00:03:32,045 --> 00:03:33,814 We're going to help paralyzed people walk again. 71 00:03:33,914 --> 00:03:36,550 The trial needs young candidates. 72 00:03:39,920 --> 00:03:42,723 Oh, wow. Are you gonna yell your way to get what you want? 73 00:03:42,856 --> 00:03:45,091 I'm not yelling. 74 00:03:45,225 --> 00:03:47,194 I'm typing. 75 00:03:47,295 --> 00:03:50,030 (banging on keyboard) 76 00:03:50,097 --> 00:03:52,300 (phone chimes) 77 00:03:57,170 --> 00:03:59,006 We live in amazing times. 78 00:03:59,106 --> 00:04:01,709 I mean, a divorced schmuck in Pittsburgh 79 00:04:01,775 --> 00:04:05,212 can sink a few grand into gene-editing equipment, 80 00:04:05,313 --> 00:04:08,148 and boom: Glowing chest. 81 00:04:08,248 --> 00:04:10,784 Yes, yes, you did it, Hobie. 82 00:04:10,884 --> 00:04:12,019 I'm not sure why you did it, 83 00:04:12,085 --> 00:04:13,621 or even if it's safe, but you did it. 84 00:04:13,754 --> 00:04:15,055 What do you mean you don't know why? 85 00:04:15,122 --> 00:04:17,391 (phone chimes) Glowing chest! 86 00:04:17,491 --> 00:04:20,260 (laughs) Ah, see, that's the thing, Hobie, 87 00:04:20,394 --> 00:04:21,762 I've never once looked at my chest 88 00:04:21,862 --> 00:04:23,864 and said, "I wish that thing could glow." 89 00:04:23,931 --> 00:04:25,599 Well, yeah, why would you? 90 00:04:25,699 --> 00:04:27,435 I mean, your pecs are glorious. 91 00:04:27,535 --> 00:04:30,371 You're, like, in the top one percent of chests worldwide. 92 00:04:30,438 --> 00:04:31,605 Ah, stop. 93 00:04:31,705 --> 00:04:32,740 Guys like me? 94 00:04:32,806 --> 00:04:33,941 We need a little shine. 95 00:04:34,074 --> 00:04:36,444 Right? Yeah, well, you're shining. 96 00:04:36,577 --> 00:04:38,446 You have to admit it's a cool idea. 97 00:04:38,579 --> 00:04:40,448 That's why you answered my emails in the first place. 98 00:04:40,581 --> 00:04:43,317 No, I recall emailing you back to advise you 99 00:04:43,417 --> 00:04:45,118 against hacking your own genome. 100 00:04:45,252 --> 00:04:46,820 So I just come to make sure you're okay and... (phone chimes) 101 00:04:46,920 --> 00:04:49,657 track the side effects of amateur biohacking. 102 00:04:50,457 --> 00:04:52,058 I... yeah, wouldn't say "amateur." 103 00:04:52,159 --> 00:04:53,694 I'm sorry, my colleagues are having trouble 104 00:04:53,794 --> 00:04:55,496 with the concept. You mind if I take a picture? 105 00:04:55,596 --> 00:04:57,130 No, no, no, go ahead. 106 00:04:57,230 --> 00:04:59,099 You don't even need a flash. All right. 107 00:04:59,166 --> 00:05:01,635 ADAM: That is a glowing chest. 108 00:05:01,769 --> 00:05:03,504 I have so many questions. 109 00:05:03,604 --> 00:05:05,172 Someone's been messing with CRISPR. 110 00:05:05,272 --> 00:05:07,841 I've seen frogs engineered with firefly genes. 111 00:05:07,941 --> 00:05:09,677 But I have never seen that. 112 00:05:09,810 --> 00:05:11,111 One man's tool to correct 113 00:05:11,178 --> 00:05:13,647 genetic mutations is another man's tool... 114 00:05:15,949 --> 00:05:17,084 Look at them. 115 00:05:17,184 --> 00:05:18,986 Mm. Look at us why? 116 00:05:19,086 --> 00:05:20,621 'Cause it's obvious what you're thinking. 117 00:05:20,721 --> 00:05:21,855 What are we thinking? 118 00:05:21,989 --> 00:05:23,190 INGRID: If that guy can get 119 00:05:23,290 --> 00:05:25,626 his chest to glow, can he also...? 120 00:05:25,726 --> 00:05:27,227 We can make a glowing penis. 121 00:05:27,327 --> 00:05:29,029 We have the technology. 122 00:05:29,162 --> 00:05:30,898 I'll alert the Nobel Committee. 123 00:05:30,998 --> 00:05:32,199 (chuckles) 124 00:05:32,332 --> 00:05:33,667 Well, anyway, you're the same as last week. 125 00:05:33,801 --> 00:05:35,102 Everything's fine. 126 00:05:35,168 --> 00:05:37,070 Yeah, I'm more than fine. 127 00:05:37,170 --> 00:05:38,105 I'm glowing. 128 00:05:38,205 --> 00:05:39,773 You're glowing. (Laughs) 129 00:05:39,873 --> 00:05:41,709 My guy. (Phone chimes) 130 00:05:41,842 --> 00:05:44,445 MARY: Her name is Taryn Quintyne. 131 00:05:44,512 --> 00:05:45,946 She's been admitted to UHOP 132 00:05:46,046 --> 00:05:47,748 five times in the past few months. 133 00:05:47,848 --> 00:05:49,617 At 26? 134 00:05:49,717 --> 00:05:51,351 Oh, sickle cell. 135 00:05:51,452 --> 00:05:52,520 I got it. 136 00:05:52,620 --> 00:05:54,087 She lives in more or less constant pain, 137 00:05:54,187 --> 00:05:55,556 and she knows there's a cure out there 138 00:05:55,689 --> 00:05:56,957 that no one will let her have. 139 00:05:57,024 --> 00:05:59,126 Well, I could fix her in a single day. 140 00:05:59,192 --> 00:06:00,394 I'm serious. 141 00:06:00,528 --> 00:06:02,062 Look, sickle cell's genetic. 142 00:06:02,162 --> 00:06:03,897 The breakthrough happened when they developed CRISPR. 143 00:06:03,997 --> 00:06:06,800 You can edit your own genome now. 144 00:06:06,900 --> 00:06:08,469 It's a tool, these drug companies 145 00:06:08,536 --> 00:06:10,037 just patented one way to use it. 146 00:06:10,137 --> 00:06:12,740 So, yes, I could fix her in a single day. 147 00:06:12,873 --> 00:06:15,208 Of course, I'd have to skip the clinical trials, 148 00:06:15,342 --> 00:06:16,610 go around the FDA, 149 00:06:16,710 --> 00:06:18,912 and then I'd be arrested, but I could fix her. 150 00:06:19,012 --> 00:06:21,381 John, join me back on Earth. 151 00:06:21,482 --> 00:06:23,851 This woman had a stroke in our ER today. 152 00:06:23,951 --> 00:06:26,687 They were slammed, and it was 20 minutes before they found her. 153 00:06:26,787 --> 00:06:30,357 Taryn Quintyne suffered alone for 20 minutes in my hospital. 154 00:06:30,457 --> 00:06:31,692 I want to help her. 155 00:06:31,792 --> 00:06:33,594 There's a clinical trial coming together. 156 00:06:33,694 --> 00:06:36,063 An alternate version of the sickle cell cure. 157 00:06:36,163 --> 00:06:37,731 I want to try to get Taryn into it, 158 00:06:37,831 --> 00:06:39,232 but with her symptoms right now... 159 00:06:39,366 --> 00:06:41,368 she's in rough shape. They'd never take her. 160 00:06:41,435 --> 00:06:44,071 So figure out why the sickle cell is worsening so rapidly, 161 00:06:44,204 --> 00:06:47,240 stabilize her so she can be eligible for the trial. 162 00:06:47,374 --> 00:06:48,442 Right, I got you. 163 00:06:48,576 --> 00:06:49,810 "I got you"? 164 00:06:49,909 --> 00:06:50,944 That's it? 165 00:06:51,044 --> 00:06:52,112 I mean, should there be more? 166 00:06:52,212 --> 00:06:54,381 You're being very cooperative. 167 00:06:54,448 --> 00:06:56,249 Is that a problem? Not a problem. 168 00:06:56,383 --> 00:06:58,986 Weird, maybe a little suspicious, 169 00:06:59,086 --> 00:07:01,254 but not a problem. 170 00:07:01,388 --> 00:07:03,190 Okay, well... 171 00:07:03,256 --> 00:07:05,392 I got you. 172 00:07:07,928 --> 00:07:09,429 TARYN: Who is that? 173 00:07:09,563 --> 00:07:11,264 Are you my doctor? 174 00:07:11,364 --> 00:07:13,033 WATSON: Are you having trouble seeing, Taryn? 175 00:07:13,133 --> 00:07:15,002 Everything is blurry. 176 00:07:15,102 --> 00:07:16,970 I hit the call button, and no one came. 177 00:07:17,104 --> 00:07:19,339 Okay, I'm here now, I'm here now. 178 00:07:19,439 --> 00:07:22,876 I need you to stay very still. 179 00:07:22,976 --> 00:07:24,578 I'm gonna shine a light into your eyes, okay? 180 00:07:24,678 --> 00:07:27,380 What is wrong with me? Am I going blind? 181 00:07:27,481 --> 00:07:29,917 Just give me one second. 182 00:07:31,952 --> 00:07:34,488 Your eyes are bleeding from the inside. 183 00:07:37,625 --> 00:07:39,827 ♪ ♪ 184 00:07:51,639 --> 00:07:53,073 You want to put a needle in my eyeball? 185 00:07:53,173 --> 00:07:55,442 Take this thing off me, please. Okay. 186 00:07:57,210 --> 00:07:59,112 The injections will help you with... 187 00:07:59,212 --> 00:08:01,949 I have spoken to four different people 188 00:08:02,082 --> 00:08:03,584 since I was admitted. 189 00:08:03,684 --> 00:08:04,885 Who is my doctor 190 00:08:04,985 --> 00:08:07,755 and what is my treatment plan? 191 00:08:07,855 --> 00:08:09,289 I'm so sorry, Taryn. 192 00:08:09,422 --> 00:08:11,925 I didn't take the time to introduce myself. 193 00:08:13,193 --> 00:08:15,996 My name is John Watson and I am your doctor. 194 00:08:16,096 --> 00:08:18,031 Myself and a team of four specialists, 195 00:08:18,131 --> 00:08:20,734 we're gonna take you on as a patient at our clinic. 196 00:08:20,834 --> 00:08:22,469 You're in good hands. 197 00:08:22,603 --> 00:08:24,271 Now, my immediate plan... 198 00:08:24,404 --> 00:08:26,173 with your permission, of course... 199 00:08:26,273 --> 00:08:28,642 will be to give you an anti-vascular 200 00:08:28,742 --> 00:08:30,377 endothelial growth factor injection, 201 00:08:30,443 --> 00:08:32,946 which should help stabilize your vision. 202 00:08:33,046 --> 00:08:34,948 You're gonna feel pressure from a needle, 203 00:08:35,048 --> 00:08:36,515 but it's not gonna hurt. 204 00:08:36,616 --> 00:08:38,485 Okay. 205 00:08:38,619 --> 00:08:40,287 All right. 206 00:08:40,386 --> 00:08:43,256 Eye hemorrhaging isn't a common side effect 207 00:08:43,356 --> 00:08:44,892 of a sickle cell episode. 208 00:08:44,992 --> 00:08:46,326 Was this your first time? 209 00:08:46,459 --> 00:08:49,697 (grunts) My first stroke, too. 210 00:08:49,797 --> 00:08:52,499 The attacks have been getting worse all year. 211 00:08:52,600 --> 00:08:55,135 Well, your stroke seemed to be relatively mild, 212 00:08:55,235 --> 00:08:56,904 but considering your age, 213 00:08:57,004 --> 00:08:59,072 the long-term trends are very concerning. 214 00:08:59,139 --> 00:09:02,075 Well, I have a journal in my bag. 215 00:09:02,142 --> 00:09:04,077 Everything that's happened, 216 00:09:04,144 --> 00:09:06,379 it's all in there. 217 00:09:11,885 --> 00:09:14,554 Doctors' names, dates seen... 218 00:09:15,488 --> 00:09:17,424 prescriptions. You're very organized. 219 00:09:17,524 --> 00:09:18,726 I'm a software engineer. 220 00:09:18,826 --> 00:09:20,761 Got to keep the code stacks tidy. 221 00:09:21,995 --> 00:09:23,530 But data, 222 00:09:23,631 --> 00:09:24,998 that's how I fight the bully. 223 00:09:25,132 --> 00:09:27,400 And a lot of good it's doing me. 224 00:09:27,500 --> 00:09:29,269 "The bully." 225 00:09:29,369 --> 00:09:30,704 It's a good name for sickle cell. 226 00:09:30,838 --> 00:09:33,974 Kicks you while you're down. But I'll tell you what. 227 00:09:34,074 --> 00:09:36,610 We're gonna help you punch back. 228 00:09:36,677 --> 00:09:38,545 But first... 229 00:09:38,646 --> 00:09:40,614 I need to help you see again. 230 00:09:42,616 --> 00:09:44,985 And I will tell you one thing that I know for sure: 231 00:09:45,085 --> 00:09:48,021 There's a cure for sickle cell. 232 00:09:49,489 --> 00:09:52,259 You definitely shouldn't be suffering like this. 233 00:09:56,730 --> 00:09:59,332 According to this journal, Taryn Quintyne has been 234 00:09:59,399 --> 00:10:02,202 hospitalized five times in three months. 235 00:10:02,335 --> 00:10:04,337 I'm sorry, that is too many times, 236 00:10:04,437 --> 00:10:05,839 even for a sickle cell patient. 237 00:10:05,939 --> 00:10:07,607 She is 26 years old. 238 00:10:07,708 --> 00:10:09,843 Her symptoms are presenting as sickle cell, 239 00:10:09,943 --> 00:10:11,912 but maybe that's a misdiagnosis. 240 00:10:12,045 --> 00:10:14,114 If hers was picked up on a newborn screening, 241 00:10:14,214 --> 00:10:16,183 methods back then were prehistoric. 242 00:10:16,249 --> 00:10:18,752 This could be hemoglobin SC disease or... 243 00:10:18,886 --> 00:10:20,353 She has sickle cell. 244 00:10:20,420 --> 00:10:22,422 Taryn Quintyne has sickle cell disease. 245 00:10:22,555 --> 00:10:24,324 In fact, let me help. 246 00:10:28,061 --> 00:10:32,099 This is a rare case where an exclamation point is necessary. 247 00:10:32,232 --> 00:10:34,902 I looked up her peripheral smear today in the lab, 248 00:10:35,002 --> 00:10:36,670 and she has sickle cell. 249 00:10:36,737 --> 00:10:38,305 INGRID: Okay, so 250 00:10:38,405 --> 00:10:40,173 opioids, fluids... 251 00:10:40,240 --> 00:10:42,075 The mystery here isn't what's wrong with Taryn Quintyne. 252 00:10:42,175 --> 00:10:45,078 No, the mystery is, why do we live in a world 253 00:10:45,178 --> 00:10:47,848 that could cure her, but won't? 254 00:10:47,915 --> 00:10:49,349 STEPHENS: Because... 255 00:10:49,415 --> 00:10:50,550 we do? 256 00:10:50,650 --> 00:10:51,685 WATSON: And what do we do about that? 257 00:10:51,752 --> 00:10:53,787 Aside from the obvious answer. 258 00:10:53,887 --> 00:10:55,622 There's an obvious answer? 259 00:10:55,723 --> 00:10:56,857 Of course there is. We have CRISPR. 260 00:10:56,924 --> 00:10:58,425 We can easily replicate a cure 261 00:10:58,525 --> 00:10:59,993 with a day of focused work. 262 00:11:00,093 --> 00:11:01,394 Honestly, we could beat it. 263 00:11:01,461 --> 00:11:04,431 Sorry. Science cured sickle cell disease, 264 00:11:04,531 --> 00:11:06,566 and you are unimpressed? 265 00:11:06,666 --> 00:11:07,835 Well, the science is impressive, 266 00:11:07,935 --> 00:11:09,402 but that's neither here nor there. 267 00:11:09,502 --> 00:11:11,571 We can't duplicate the cure because, of course, 268 00:11:11,638 --> 00:11:13,240 that would be "illegal." 269 00:11:13,306 --> 00:11:15,542 I don't think you need air quotes for that. 270 00:11:15,642 --> 00:11:16,977 WATSON: We can proceed 271 00:11:17,110 --> 00:11:18,545 on three fronts. 272 00:11:18,611 --> 00:11:21,214 Make sure there's nothing else wrong with Taryn 273 00:11:21,314 --> 00:11:23,550 that's causing the escalation of her symptoms. 274 00:11:23,650 --> 00:11:26,286 Twins, you two supervise a high performance 275 00:11:26,386 --> 00:11:28,221 liquid chromatography test. 276 00:11:28,321 --> 00:11:31,391 Monitor Taryn's recovery from this crisis. 277 00:11:31,491 --> 00:11:34,027 Decrease the frequency of the episodes 278 00:11:34,127 --> 00:11:35,729 so she's eligible for clinical trials. 279 00:11:35,796 --> 00:11:38,298 Dr. Derian, Dr. Lubbock, that's on you. 280 00:11:38,398 --> 00:11:39,800 You can also look through her journal 281 00:11:39,933 --> 00:11:41,201 for more clues while you're at it. 282 00:11:41,301 --> 00:11:42,870 INGRID: You held up two fingers. 283 00:11:42,970 --> 00:11:45,338 You said we'd proceed on three fronts. 284 00:11:45,472 --> 00:11:46,506 You held up two fingers. 285 00:11:46,606 --> 00:11:49,609 There's a cure for sickle cell. 286 00:11:49,676 --> 00:11:51,211 The science is mediocre, 287 00:11:51,311 --> 00:11:53,646 the cost is $3 million out of pocket, 288 00:11:53,747 --> 00:11:56,049 and it's the property of a lawyered-up monolith, 289 00:11:56,149 --> 00:11:58,819 but it does exist. 290 00:11:58,952 --> 00:12:01,421 Our patient will have it. 291 00:12:05,158 --> 00:12:06,860 SASHA: Taryn can see. 292 00:12:06,960 --> 00:12:08,829 The anti-VEGF injections worked. 293 00:12:08,929 --> 00:12:10,530 Hydromorphone's helping with the pain. 294 00:12:10,663 --> 00:12:12,900 She's on her way to some relief. 295 00:12:13,700 --> 00:12:15,035 Anything in her journal? 296 00:12:15,168 --> 00:12:16,503 She's getting worse. More symptoms, more often. 297 00:12:16,603 --> 00:12:17,737 The time between 298 00:12:17,838 --> 00:12:20,007 each crisis keeps shrinking. 299 00:12:20,808 --> 00:12:22,876 How would you do this? 300 00:12:22,976 --> 00:12:23,977 I want this patient 301 00:12:24,077 --> 00:12:25,478 admitted to my spinal project. 302 00:12:25,578 --> 00:12:27,881 The chairman has dismissed two of my candidates. 303 00:12:28,648 --> 00:12:31,118 You're ruthless. How would you get this one in? 304 00:12:31,184 --> 00:12:33,186 I beg your pardon? 305 00:12:33,320 --> 00:12:34,587 I am not ruthless. 306 00:12:34,687 --> 00:12:36,623 Did you work group projects in med school? 307 00:12:36,723 --> 00:12:38,158 Mm. Okay, when you were on one, 308 00:12:38,225 --> 00:12:40,660 and you didn't like how it was going, what'd you do? 309 00:12:40,760 --> 00:12:42,495 Took on all the work. 310 00:12:42,595 --> 00:12:44,231 Offered to write up the project 311 00:12:44,364 --> 00:12:45,532 so I could throw out any bad ideas. 312 00:12:45,665 --> 00:12:46,867 Made sure the professors 313 00:12:47,000 --> 00:12:48,368 knew who did everything. 314 00:12:48,468 --> 00:12:50,137 I mean, you can't come out and say that, obviously, 315 00:12:50,203 --> 00:12:51,872 but there are ways. 316 00:12:51,972 --> 00:12:53,673 You would beat up a baby 317 00:12:53,773 --> 00:12:55,575 if it stood in between you and an "A." 318 00:12:55,675 --> 00:12:57,878 Babies can't stand. 319 00:12:58,879 --> 00:13:00,613 What do I do here? 320 00:13:01,648 --> 00:13:04,084 Teach me your sinister ways. 321 00:13:05,685 --> 00:13:07,154 (chuckles) 322 00:13:07,220 --> 00:13:09,189 All right. 323 00:13:09,256 --> 00:13:10,991 "Gigi Grigoryan." 324 00:13:11,058 --> 00:13:12,092 Who is she? 325 00:13:12,225 --> 00:13:13,660 Someone I want in the trial. 326 00:13:13,760 --> 00:13:14,928 You need to tell a story. 327 00:13:15,028 --> 00:13:17,230 Why should it be Gigi? 328 00:13:17,364 --> 00:13:20,133 Make a case, pull some heartstrings, 329 00:13:20,233 --> 00:13:22,369 drop a hint as to what could possibly happen 330 00:13:22,469 --> 00:13:23,503 if the trial excludes 331 00:13:23,570 --> 00:13:25,405 deserving young candidates like her. 332 00:13:25,505 --> 00:13:27,674 You ruthless bitch. 333 00:13:27,774 --> 00:13:29,176 You have to be subtle. 334 00:13:29,242 --> 00:13:30,710 It's not a threat. 335 00:13:30,810 --> 00:13:34,414 You're just... voicing concern. 336 00:13:35,849 --> 00:13:38,418 SHINWELL: You're quiet today, guv. 337 00:13:38,518 --> 00:13:41,154 No. Big ideas brewing in there tonight, eh? 338 00:13:41,254 --> 00:13:43,623 I think I left the lights on in my bathroom. 339 00:13:44,557 --> 00:13:45,592 Strikes me 340 00:13:45,725 --> 00:13:47,094 that this plan of yours... 341 00:13:47,227 --> 00:13:50,763 Oh, I don't know, let's review it, shall we? 342 00:13:50,898 --> 00:13:52,866 Quick trip to New York City. 343 00:13:52,933 --> 00:13:53,901 Mm-hmm. 344 00:13:53,967 --> 00:13:56,536 Vague plans for a sit-down 345 00:13:56,636 --> 00:13:58,671 with someone 346 00:13:58,771 --> 00:14:00,640 from a major biotech company. 347 00:14:00,740 --> 00:14:01,608 Mm-hmm. 348 00:14:01,708 --> 00:14:02,910 No appointment of any kind. 349 00:14:02,976 --> 00:14:03,977 None. 350 00:14:04,111 --> 00:14:05,445 And this is meant to end 351 00:14:05,578 --> 00:14:06,947 with the young lady getting 352 00:14:07,047 --> 00:14:08,882 a $3 million product free of charge? 353 00:14:08,949 --> 00:14:11,751 Well, I wouldn't say free of charge. 354 00:14:11,818 --> 00:14:14,587 Their cure is just sloppy and suboptimal. 355 00:14:14,654 --> 00:14:15,989 They edit too much of the genome. 356 00:14:16,123 --> 00:14:17,790 Why would you 357 00:14:17,925 --> 00:14:19,626 cut out an entire chapter of a book 358 00:14:19,726 --> 00:14:20,894 when all you have to do 359 00:14:20,961 --> 00:14:22,629 is replace a single spelling mistake? 360 00:14:23,563 --> 00:14:25,132 So, in exchange for access 361 00:14:25,232 --> 00:14:27,400 to a cure that you describe 362 00:14:27,467 --> 00:14:30,103 as "sloppy and suboptimal..." 363 00:14:30,170 --> 00:14:31,304 Mm-hmm. ...You will... 364 00:14:31,438 --> 00:14:32,505 Improve that cure. 365 00:14:32,605 --> 00:14:34,141 You know full well 366 00:14:34,241 --> 00:14:35,875 this is a suicide mission. 367 00:14:37,310 --> 00:14:39,279 Question is, 368 00:14:39,379 --> 00:14:41,148 why are you taking it on, 369 00:14:41,281 --> 00:14:43,483 and what are you planning for after 370 00:14:43,583 --> 00:14:44,918 it fails? (Phone buzzing) 371 00:14:45,785 --> 00:14:48,388 Stephens, what can I do for you? 372 00:14:50,023 --> 00:14:51,858 We have to turn around. 373 00:14:51,959 --> 00:14:52,993 (groaning) 374 00:14:53,093 --> 00:14:55,128 The pain came back all at once. 375 00:14:55,195 --> 00:14:57,497 We threw the kitchen sink at it. 376 00:14:57,597 --> 00:15:00,233 L-glutamine. Crizanlizumab. 377 00:15:00,333 --> 00:15:02,769 Hydromorphone PCA so she can rest. 378 00:15:02,835 --> 00:15:04,437 She shouldn't be having another crisis. 379 00:15:04,537 --> 00:15:06,339 Another crisis, the same crisis, 380 00:15:06,439 --> 00:15:07,807 one big crisis that hasn't really 381 00:15:07,907 --> 00:15:09,609 stopped for months. 382 00:15:09,709 --> 00:15:11,011 Who's to say? 383 00:15:11,111 --> 00:15:12,645 The results of her high performance 384 00:15:12,712 --> 00:15:14,214 liquid chromatography test came back. 385 00:15:14,347 --> 00:15:16,516 She has a rare form of sickle cell. 386 00:15:16,649 --> 00:15:18,185 Adam and I called 387 00:15:18,285 --> 00:15:19,719 five different hematologists. 388 00:15:19,852 --> 00:15:22,089 None of them have seen this outside of textbooks. 389 00:15:23,856 --> 00:15:26,893 Taryn's latest bloodwork. 390 00:15:28,428 --> 00:15:31,198 Her hemoglobin levels are plummeting. 391 00:15:31,298 --> 00:15:32,865 We'll keep giving her transfusions 392 00:15:32,966 --> 00:15:35,068 and managing her pain... 393 00:15:35,168 --> 00:15:36,903 Why, so she can live in crisis 394 00:15:37,037 --> 00:15:38,838 until her body finally quits on her? 395 00:15:38,905 --> 00:15:40,873 I don't like this any more than you do, 396 00:15:40,974 --> 00:15:43,043 but it's our best option. 397 00:15:44,844 --> 00:15:47,214 (moans) 398 00:15:50,083 --> 00:15:51,884 Morning, guv. 399 00:15:53,053 --> 00:15:55,155 Can I be of service here, 400 00:15:55,255 --> 00:15:57,090 guv? Actually, 401 00:15:57,190 --> 00:15:58,558 I could use your advice. 402 00:15:58,658 --> 00:15:59,759 It's about Plan B. 403 00:15:59,859 --> 00:16:01,828 Which was Plan A all along. 404 00:16:01,928 --> 00:16:04,497 This advice, though, it could involve 405 00:16:04,597 --> 00:16:06,733 bringing you into something that... 406 00:16:06,833 --> 00:16:08,335 could have implications 407 00:16:08,435 --> 00:16:10,370 down the line. Mm-hmm. 408 00:16:10,470 --> 00:16:11,704 I'm saying it's not safe for us 409 00:16:11,771 --> 00:16:13,873 to have the conversation I want to have. 410 00:16:13,940 --> 00:16:16,709 And yet... here we are. 411 00:16:16,809 --> 00:16:18,778 Listen, I can make this patient better. 412 00:16:18,911 --> 00:16:20,813 Thing is, I'd have to get around 413 00:16:20,913 --> 00:16:23,116 the FDA, the administration at UHOP, 414 00:16:23,250 --> 00:16:26,319 including Mary, and the law to do it. 415 00:16:26,419 --> 00:16:27,287 (gasps) 416 00:16:27,420 --> 00:16:28,621 You're planning a job. 417 00:16:28,721 --> 00:16:30,090 No, I wouldn't put it that way. 418 00:16:30,190 --> 00:16:31,791 You're talking about a crime, yeah? 419 00:16:31,891 --> 00:16:35,628 It is against the law for me to cure Taryn Quintyne, yes. 420 00:16:35,762 --> 00:16:37,564 So you're planning a job, then. 421 00:16:37,664 --> 00:16:39,832 And to that, I say... 422 00:16:41,901 --> 00:16:43,703 you've come to the right man. 423 00:16:49,342 --> 00:16:50,443 All righty, then. So, 424 00:16:50,543 --> 00:16:51,644 when you are planning a job... 425 00:16:51,744 --> 00:16:52,912 Ah, there's that phrase again. "Job." 426 00:16:53,012 --> 00:16:54,914 When you are planning a job, 427 00:16:55,014 --> 00:16:56,349 first order of business 428 00:16:56,415 --> 00:16:58,518 is limiting one's exposure. 429 00:16:58,618 --> 00:17:01,254 That means as few accomplices 430 00:17:01,354 --> 00:17:02,555 as possible. I object 431 00:17:02,689 --> 00:17:04,090 to the word "accomplices." 432 00:17:04,191 --> 00:17:06,693 Well, you object all you like. 433 00:17:06,759 --> 00:17:08,127 If you go through with this, 434 00:17:08,228 --> 00:17:09,596 you're gonna be putting your career 435 00:17:09,695 --> 00:17:12,031 into the hands of other people. 436 00:17:12,098 --> 00:17:13,965 Other people do not share 437 00:17:14,067 --> 00:17:15,001 your interests. 438 00:17:15,068 --> 00:17:16,703 Thank you for pointing that out. 439 00:17:16,803 --> 00:17:18,570 Meaning, the fewer, the better. 440 00:17:18,671 --> 00:17:20,272 Now, I'm already in, 441 00:17:20,406 --> 00:17:22,974 but we'll take that as square. 442 00:17:23,076 --> 00:17:25,044 You have plenty of information 443 00:17:25,145 --> 00:17:28,013 about my criminal activities. 444 00:17:28,080 --> 00:17:29,449 Now, I'll have some about yours. 445 00:17:29,582 --> 00:17:30,917 "Criminal activities?" 446 00:17:31,017 --> 00:17:33,553 Do not shy away from accurate phrasing, guv. 447 00:17:33,653 --> 00:17:35,255 It's not a good look. 448 00:17:35,355 --> 00:17:37,857 So, me. The patient, of course. 449 00:17:37,924 --> 00:17:39,126 Who else? 450 00:17:39,259 --> 00:17:40,627 I need someone skillful 451 00:17:40,727 --> 00:17:41,961 to help me with the procedures. 452 00:17:42,095 --> 00:17:43,463 Hobie McSorley comes to mind. 453 00:17:43,596 --> 00:17:45,432 Hobie. Hobie. 454 00:17:45,532 --> 00:17:47,867 The man who wants to turn his knob into a glow stick? 455 00:17:47,967 --> 00:17:50,103 Okay, well, he may aim low, but Hobie's got game. 456 00:17:50,237 --> 00:17:52,004 He already operates extra-legally. 457 00:17:52,105 --> 00:17:54,474 Another bent man. That's good. 458 00:17:54,607 --> 00:17:56,876 And actually, for what I need here, 459 00:17:56,976 --> 00:17:58,211 I would take Hobie over 460 00:17:58,278 --> 00:18:00,713 any of the fellows. Yeah, 461 00:18:00,813 --> 00:18:02,615 the fellows. 462 00:18:03,950 --> 00:18:05,718 Lovely young people, 463 00:18:05,785 --> 00:18:07,053 but not hard folk. 464 00:18:07,154 --> 00:18:08,455 I wouldn't trust a single 465 00:18:08,588 --> 00:18:11,758 one of them to hold up under questioning. 466 00:18:11,858 --> 00:18:12,925 Maybe Ingrid. 467 00:18:12,992 --> 00:18:13,960 Yeah, you're right. 468 00:18:14,060 --> 00:18:16,163 They can't know. Agreed. 469 00:18:16,296 --> 00:18:18,231 What's next? Next? 470 00:18:18,298 --> 00:18:22,335 Next, you recruit your gang. 471 00:18:23,270 --> 00:18:25,572 (indistinct P.A. announcement) 472 00:18:25,672 --> 00:18:27,073 WATSON: Pain's not too bad? 473 00:18:30,009 --> 00:18:34,147 Listen, we failed you, Taryn. 474 00:18:34,247 --> 00:18:35,948 It's easy to say it like that, "we," 475 00:18:36,048 --> 00:18:38,117 because when everyone's to blame, 476 00:18:38,185 --> 00:18:41,154 then, truly, no one really is. 477 00:18:41,954 --> 00:18:43,022 But I'd like to offer you 478 00:18:43,156 --> 00:18:44,457 something more than sympathy. 479 00:18:44,557 --> 00:18:45,758 What is that? 480 00:18:45,858 --> 00:18:47,360 With your permission, 481 00:18:47,460 --> 00:18:50,062 I'd like to do a procedure called base repair editing. 482 00:18:50,163 --> 00:18:51,864 We'd start by drawing your blood, 483 00:18:51,998 --> 00:18:53,500 collecting your stem cells, 484 00:18:53,600 --> 00:18:56,035 then we create a base editor. 485 00:18:56,169 --> 00:18:57,870 It's a microscopic tool 486 00:18:58,004 --> 00:18:59,672 that would correct the mutation 487 00:18:59,772 --> 00:19:02,309 that's causing your sickle cell. 488 00:19:02,375 --> 00:19:03,810 From there, I'd drill into your shin, 489 00:19:03,876 --> 00:19:05,478 tapping into your bone marrow, 490 00:19:05,578 --> 00:19:08,281 where the edited cells will replicate. 491 00:19:08,348 --> 00:19:10,883 You should feel better quickly. 492 00:19:10,983 --> 00:19:12,252 Feel better? 493 00:19:12,352 --> 00:19:14,954 I'm talking about a cure, Taryn. 494 00:19:15,054 --> 00:19:17,123 And if things go the way I hope, 495 00:19:17,190 --> 00:19:19,259 you'd be free of the disease. 496 00:19:19,359 --> 00:19:20,960 The current cures 497 00:19:21,027 --> 00:19:22,662 on the market, they require 498 00:19:22,762 --> 00:19:24,163 a stem cell ablation. 499 00:19:24,231 --> 00:19:27,734 It's chemotherapy that could leave you infertile. 500 00:19:27,834 --> 00:19:28,868 This is different. 501 00:19:29,001 --> 00:19:31,538 I could still have a baby? 502 00:19:31,671 --> 00:19:33,706 Yes. 503 00:19:33,806 --> 00:19:35,675 Now, I just need the guy. 504 00:19:35,775 --> 00:19:37,176 (chuckles) 505 00:19:37,244 --> 00:19:39,679 Come on, an accomplished software engineer, 506 00:19:39,746 --> 00:19:41,214 valedictorian of Allderdice, 507 00:19:41,348 --> 00:19:42,682 class of 2016? 508 00:19:42,782 --> 00:19:44,717 Listen, I hope I'm not overstepping my bounds, 509 00:19:44,817 --> 00:19:47,720 but I find it hard to believe that you're single. 510 00:19:47,820 --> 00:19:50,690 Mm-hmm. (Chuckles) 511 00:19:50,757 --> 00:19:54,327 Happened right before my last crisis. 512 00:19:56,363 --> 00:19:59,966 George is a good guy, he just... 513 00:20:01,601 --> 00:20:03,770 got tired. 514 00:20:03,870 --> 00:20:07,006 The hospital visits, the pain. 515 00:20:08,275 --> 00:20:10,443 It's a lot. 516 00:20:12,512 --> 00:20:15,081 This procedure... 517 00:20:16,549 --> 00:20:19,252 it sounds like the answer to all of my problems. 518 00:20:19,352 --> 00:20:20,853 Why is this the first time 519 00:20:20,953 --> 00:20:22,054 I'm hearing about it? 520 00:20:22,154 --> 00:20:23,623 No one's ever tried it before. 521 00:20:23,756 --> 00:20:25,292 Now, I believe that it's safe, 522 00:20:25,425 --> 00:20:28,094 and I believe that the red tape is the only reason 523 00:20:28,227 --> 00:20:29,429 you can't get it already. 524 00:20:29,529 --> 00:20:32,765 This is not an approved procedure. 525 00:20:32,865 --> 00:20:34,801 If we do this, 526 00:20:34,901 --> 00:20:36,669 I'm putting my career in your hands. 527 00:20:36,769 --> 00:20:38,771 You can't tell anyone what happened, 528 00:20:38,905 --> 00:20:41,608 even when you start to feel better. 529 00:20:42,442 --> 00:20:44,577 You could lose your job. Yes. 530 00:20:44,644 --> 00:20:47,314 If something happens, I... 531 00:20:47,447 --> 00:20:49,616 I could lose my freedom. 532 00:20:51,217 --> 00:20:52,785 Why would you do this? 533 00:20:52,885 --> 00:20:55,021 'Cause no one else will. 534 00:20:55,822 --> 00:20:57,990 'Cause you deserve it. 535 00:20:58,090 --> 00:20:59,892 And because I'm your doctor. 536 00:20:59,992 --> 00:21:02,729 I'm sure you know the sickle cell trait 537 00:21:02,829 --> 00:21:04,631 protected our ancestors against malaria. 538 00:21:04,731 --> 00:21:09,201 Now it just causes suffering in our community. 539 00:21:10,303 --> 00:21:12,705 I'm sick and tired of standing by watching 540 00:21:12,805 --> 00:21:15,408 when I know that I can do something. 541 00:21:18,478 --> 00:21:20,146 How would it work? 542 00:21:20,279 --> 00:21:23,149 WATSON: We'll do it before you get any weaker. 543 00:21:23,249 --> 00:21:25,051 In my clinic tonight. 544 00:21:25,151 --> 00:21:27,787 Dr. Watson asked me to tell you that he's transferring 545 00:21:27,854 --> 00:21:30,990 the current patient to another department. 546 00:21:31,090 --> 00:21:32,291 Is she stable? 547 00:21:32,359 --> 00:21:33,526 Dr. Watson says 548 00:21:33,626 --> 00:21:35,362 her hematologist can take it from here. 549 00:21:35,462 --> 00:21:38,665 He instructs you two to round on your other patients, 550 00:21:38,798 --> 00:21:42,335 look through the referrals for other cases of interest. 551 00:21:44,203 --> 00:21:46,439 STEPHENS: Sounds like something a normal doctor would say. 552 00:21:46,506 --> 00:21:48,875 It does not sound like something Watson would say. 553 00:21:48,975 --> 00:21:50,477 What are you suggesting? 554 00:21:50,577 --> 00:21:52,278 I'm not sure. 555 00:21:53,380 --> 00:21:55,482 Maybe nothing. 556 00:21:55,548 --> 00:21:57,884 So, I am taking a chip next week. 557 00:21:57,984 --> 00:21:59,786 It's October already? 558 00:21:59,886 --> 00:22:01,253 Snuck up on me. 559 00:22:01,354 --> 00:22:04,190 Yeah. Five years sober is major. 560 00:22:04,290 --> 00:22:05,692 I'd love it if you'd come. 561 00:22:05,825 --> 00:22:08,561 Bring the woman you're seeing if you like. 562 00:22:08,695 --> 00:22:10,129 I'd love to meet her. 563 00:22:10,196 --> 00:22:11,631 Wait. 564 00:22:11,731 --> 00:22:13,366 Five years? 565 00:22:13,466 --> 00:22:14,701 You started rehab 566 00:22:14,801 --> 00:22:16,068 sophomore year of college. 567 00:22:16,202 --> 00:22:17,336 I relapsed. 568 00:22:17,404 --> 00:22:19,038 Lasted about a month. 569 00:22:19,171 --> 00:22:22,542 Come next week, you can hear all about it. 570 00:22:22,675 --> 00:22:24,343 WATSON: It'll have to be late. 571 00:22:24,411 --> 00:22:25,678 (elevator bell dings) 572 00:22:25,778 --> 00:22:29,081 Once everyone goes home for the night, 573 00:22:29,181 --> 00:22:31,117 we can get started. 574 00:22:40,560 --> 00:22:42,328 (elevator bell dings) 575 00:22:49,569 --> 00:22:51,504 (beeping) 576 00:22:51,571 --> 00:22:53,105 (clicks) 577 00:22:53,205 --> 00:22:56,609 That's the blood sample we took when you were admitted. 578 00:22:56,709 --> 00:23:00,079 My, um, colleague Hobie has been editing your blood 579 00:23:00,179 --> 00:23:02,549 according to my instructions, 580 00:23:02,615 --> 00:23:03,783 and... 581 00:23:03,883 --> 00:23:06,185 here are the results. 582 00:23:09,255 --> 00:23:11,991 Why are those ones glowing? 583 00:23:12,091 --> 00:23:15,227 Firefly luciferase reporter, for studying gene regulation. 584 00:23:15,327 --> 00:23:17,263 That's how we know the edit was successful. 585 00:23:17,363 --> 00:23:18,765 Don't worry, you won't glow. 586 00:23:18,865 --> 00:23:22,034 Oh, but if you wanted to, this is what it looks like. 587 00:23:22,134 --> 00:23:23,736 Hobie. 588 00:23:23,836 --> 00:23:24,771 (chuckles softly) 589 00:23:24,871 --> 00:23:27,974 But those... those cells mean... 590 00:23:28,074 --> 00:23:29,275 it's working? 591 00:23:29,375 --> 00:23:31,444 WATSON: So far, so good. Yes. 592 00:23:31,544 --> 00:23:33,780 You have a mole on your shin. 593 00:23:33,880 --> 00:23:36,148 I'm gonna use a tool called an intraosseous drill 594 00:23:36,282 --> 00:23:37,717 to drill into it. 595 00:23:37,817 --> 00:23:39,418 Now, if anyone asks, 596 00:23:39,519 --> 00:23:42,822 I was concerned about the mole, so I removed it as a precaution. 597 00:23:43,656 --> 00:23:45,157 You're gonna cure my sickle cell 598 00:23:45,257 --> 00:23:47,494 and cover it up as a mole removal? 599 00:23:47,594 --> 00:23:50,930 That-that was my idea, the mole bit there. 600 00:23:51,030 --> 00:23:52,198 (clears throat) 601 00:23:53,399 --> 00:23:55,367 WATSON: The anesthetic that I applied earlier 602 00:23:55,468 --> 00:23:57,336 already has your shin numb. 603 00:23:57,436 --> 00:23:59,906 The benzos will keep you relaxed while I drill. 604 00:24:00,006 --> 00:24:01,541 SHINWELL: This... 605 00:24:01,674 --> 00:24:03,743 works a treat. 606 00:24:03,843 --> 00:24:05,344 Or you can squeeze my hand. 607 00:24:05,444 --> 00:24:06,846 The ball. Thank you. 608 00:24:06,979 --> 00:24:08,815 WATSON: So, once we've made the hole, 609 00:24:08,915 --> 00:24:12,652 we'll infuse an IV full of edited blood into your bone. 610 00:24:12,752 --> 00:24:15,054 Over time, the healthy cells will replicate 611 00:24:15,154 --> 00:24:16,956 and replace the diseased ones. 612 00:24:17,056 --> 00:24:18,725 And that's it? 613 00:24:18,858 --> 00:24:20,226 No more bully? 614 00:24:20,326 --> 00:24:21,628 That's what I expect, 615 00:24:21,694 --> 00:24:22,829 that's what I believe, 616 00:24:22,929 --> 00:24:25,264 but it is new science. 617 00:24:25,364 --> 00:24:27,867 We both have a lot on the line here, Taryn, 618 00:24:28,000 --> 00:24:29,636 but it is your body. 619 00:24:29,702 --> 00:24:32,872 If you want to back out, now is the time. 620 00:24:36,809 --> 00:24:38,210 Cure me. 621 00:24:38,310 --> 00:24:40,379 ♪ ♪ 622 00:24:44,150 --> 00:24:46,352 (tool whirring) 623 00:24:51,891 --> 00:24:54,060 (beeping) 624 00:25:08,941 --> 00:25:10,777 That's it? WATSON: Yes. 625 00:25:10,877 --> 00:25:11,944 For tonight. 626 00:25:12,078 --> 00:25:13,680 But if you are ever interested 627 00:25:13,746 --> 00:25:16,983 in a different kind of glow-up, you know who to call. 628 00:25:18,551 --> 00:25:21,621 So, we'll monitor you over the next couple of days, 629 00:25:21,721 --> 00:25:23,790 but remember, even if you feel better, 630 00:25:23,890 --> 00:25:26,092 you're gonna have to still say that the pain 631 00:25:26,192 --> 00:25:28,160 comes and goes. 632 00:25:29,629 --> 00:25:30,897 Taryn? 633 00:25:30,997 --> 00:25:32,464 Sorry. Yeah. 634 00:25:32,565 --> 00:25:34,300 Of course. 635 00:25:36,235 --> 00:25:38,504 I can't believe that's all it took. 636 00:25:39,939 --> 00:25:42,174 Thank you. 637 00:25:46,913 --> 00:25:49,081 You'll need to sign for the mole removal. 638 00:25:49,148 --> 00:25:50,583 Guv. 639 00:25:51,383 --> 00:25:54,453 Are you, by chance, the man with the glowing chest? 640 00:25:58,457 --> 00:26:00,326 You have a birthmark on your collarbone. 641 00:26:00,426 --> 00:26:01,728 It's shaped a little bit like 642 00:26:01,828 --> 00:26:03,362 the country of Luxembourg, and it extends 643 00:26:03,462 --> 00:26:05,164 above the hem of your shirt. 644 00:26:05,264 --> 00:26:06,833 Shinwell, will you take Ms. Quintyne 645 00:26:06,933 --> 00:26:10,970 to her room, please, while I talk to my colleagues? 646 00:26:14,506 --> 00:26:16,776 Hobie, thanks for everything. Yeah. 647 00:26:16,843 --> 00:26:18,678 Good seeing you again. Yeah. 648 00:26:19,779 --> 00:26:21,480 Good deduction with the birthmark. 649 00:26:21,580 --> 00:26:26,018 Sometimes I forget how well you all are coming along. 650 00:26:27,086 --> 00:26:28,655 Something you want to talk about? 651 00:26:28,755 --> 00:26:29,922 INGRID: Fringe scientist, 652 00:26:30,022 --> 00:26:32,524 patient in need of a fringe cure. 653 00:26:32,625 --> 00:26:33,993 We were just curious. 654 00:26:34,093 --> 00:26:36,328 What happened in there? 655 00:26:37,563 --> 00:26:40,667 Did you commit a crime? 656 00:26:48,540 --> 00:26:50,409 ADAM: You're not saying anything. 657 00:26:50,542 --> 00:26:51,911 You don't want me to say anything. 658 00:26:52,011 --> 00:26:53,713 Whatever I might have done tonight 659 00:26:53,780 --> 00:26:57,750 doesn't affect any of you unless and until you know about it. 660 00:26:57,850 --> 00:27:01,420 Then, if something happened, there's a duty to report. 661 00:27:01,520 --> 00:27:03,756 And see, that's when things get complicated, 662 00:27:03,890 --> 00:27:07,593 so my question to you is: Why are you asking questions? 663 00:27:08,427 --> 00:27:10,129 I'm good. 664 00:27:10,930 --> 00:27:12,531 Ignorance is bliss. STEPHENS: No. 665 00:27:14,100 --> 00:27:16,335 I personally spent a decade studying 666 00:27:16,435 --> 00:27:18,237 so I could get into Hopkins for med school. 667 00:27:18,337 --> 00:27:20,072 As some of you may have noticed, I wrecked 668 00:27:20,139 --> 00:27:21,774 my social learning curve in the doing of it 669 00:27:21,908 --> 00:27:24,076 and may have condemned myself to a life of solitude 670 00:27:24,143 --> 00:27:25,644 and broken relationships. 671 00:27:26,913 --> 00:27:28,647 After all of that, 672 00:27:28,781 --> 00:27:30,182 I chose you. 673 00:27:30,282 --> 00:27:33,552 I chose this place as the staging ground for my career. 674 00:27:33,652 --> 00:27:35,487 I deserve t... 675 00:27:36,322 --> 00:27:40,960 We all deserve to know if that was a stupid choice. 676 00:27:45,898 --> 00:27:48,634 Taryn Quintyne is going to be fine. 677 00:27:48,735 --> 00:27:50,803 She's gonna live a long and healthy life, 678 00:27:50,903 --> 00:27:53,005 all because of what I did tonight. 679 00:27:53,139 --> 00:27:56,042 The procedure's called base repair editing. 680 00:27:56,142 --> 00:27:57,576 I think it's 681 00:27:57,643 --> 00:28:00,312 grotesque that a young woman 682 00:28:00,412 --> 00:28:03,082 should be condemned to die at a young age 683 00:28:03,182 --> 00:28:06,185 waiting for an easily obtainable cure. 684 00:28:06,285 --> 00:28:07,653 And that's why I did it. 685 00:28:07,754 --> 00:28:11,123 Now, if I've hired the people I believed I was hiring, 686 00:28:11,223 --> 00:28:13,359 I think you'll all see that. 687 00:28:13,459 --> 00:28:14,761 If not, 688 00:28:14,861 --> 00:28:16,462 I feel content 689 00:28:16,528 --> 00:28:19,065 that I did the right thing for my patient. 690 00:28:23,402 --> 00:28:25,671 You all have a decision to make. 691 00:28:27,373 --> 00:28:29,508 I will leave you to it. 692 00:28:31,343 --> 00:28:33,545 (footsteps receding) 693 00:28:37,750 --> 00:28:39,518 STEPHENS: We shouldn't be in this position. 694 00:28:39,618 --> 00:28:40,987 INGRID: We wouldn't be in this position 695 00:28:41,053 --> 00:28:42,588 if you didn't bring us all down here. 696 00:28:42,688 --> 00:28:45,024 We are a team! It's called camaraderie. 697 00:28:46,225 --> 00:28:47,693 Are we just supposed to risk our careers 698 00:28:47,794 --> 00:28:49,161 for Watson's act of hubris? 699 00:28:49,261 --> 00:28:51,864 Your career's only at risk if you're tied to it. 700 00:28:51,998 --> 00:28:54,100 You weren't before, but you are now. 701 00:28:55,401 --> 00:28:56,936 We're assuming this is gonna be a catastrophe, 702 00:28:57,036 --> 00:28:59,605 but what if Taryn just... gets better? 703 00:29:00,372 --> 00:29:02,174 You're going along with this? 704 00:29:02,241 --> 00:29:04,777 Watson may be reckless, but he's also a genius. 705 00:29:04,877 --> 00:29:07,679 Why don't we just see what happens? 706 00:29:07,780 --> 00:29:10,716 Watson said it himself... we have a duty to report. 707 00:29:10,850 --> 00:29:11,951 True. 708 00:29:12,051 --> 00:29:13,219 But the only people who know 709 00:29:13,352 --> 00:29:16,055 that we know what we know are Watson 710 00:29:16,188 --> 00:29:17,523 and us. 711 00:29:17,589 --> 00:29:18,891 Even if this blows up, 712 00:29:19,025 --> 00:29:21,861 as long as the four of us don't say anything, 713 00:29:21,928 --> 00:29:23,830 we're protected. 714 00:29:23,930 --> 00:29:25,464 (scoffs) 715 00:29:26,265 --> 00:29:28,067 Don't look so surprised. 716 00:29:28,167 --> 00:29:29,836 Sasha's ruthless. 717 00:29:31,570 --> 00:29:34,440 You're the only one who hasn't said anything. 718 00:29:36,909 --> 00:29:39,111 We have the knowledge to cure Taryn Quintyne, 719 00:29:39,211 --> 00:29:42,081 and yet we refuse to do it. 720 00:29:43,049 --> 00:29:45,117 What else is there to say? 721 00:29:48,054 --> 00:29:49,321 (Shinwell clears throat) 722 00:29:54,961 --> 00:29:56,996 SHINWELL: The young lady's blood cells, 723 00:29:57,096 --> 00:29:59,698 drawn after the procedure. 724 00:29:59,765 --> 00:30:01,500 I'm no scientist, 725 00:30:01,600 --> 00:30:04,603 so I'll leave the thinking to you. 726 00:30:06,305 --> 00:30:08,474 ♪ ♪ 727 00:30:25,391 --> 00:30:27,593 ♪ ♪ 728 00:30:43,609 --> 00:30:45,577 Wow. Those look very good. 729 00:30:45,644 --> 00:30:47,479 Thank you. 730 00:30:47,579 --> 00:30:48,948 I haven't seen you before. 731 00:30:49,015 --> 00:30:50,682 Are you, uh, one of Taryn's doctors? 732 00:30:50,782 --> 00:30:52,184 I'm the medical director here, 733 00:30:52,318 --> 00:30:53,319 Mary Morstan. 734 00:30:53,452 --> 00:30:55,454 I'm just checking up on her. 735 00:30:56,288 --> 00:30:57,623 Well, George Carver. 736 00:30:57,689 --> 00:30:59,225 Yes, middle initial "W." 737 00:30:59,325 --> 00:31:00,859 Yes, my-my parents named me after the person 738 00:31:00,993 --> 00:31:02,929 who came up with 300 ways to use a peanut. 739 00:31:02,995 --> 00:31:04,596 (chuckles) I'm Taryn's... 740 00:31:04,663 --> 00:31:07,433 Um, we used to be together. 741 00:31:07,499 --> 00:31:09,501 Mm. We were a good team. 742 00:31:09,601 --> 00:31:11,770 You know, the illustrator and the STEM girl. 743 00:31:11,837 --> 00:31:14,340 (chuckles) Screwed up there. 744 00:31:14,473 --> 00:31:17,876 So, how is she doing this morning? 745 00:31:18,844 --> 00:31:20,947 She's been asleep since I got here. Mm. 746 00:31:22,014 --> 00:31:23,282 She gonna be okay? 747 00:31:23,349 --> 00:31:25,751 Her vitals have been improving 748 00:31:25,851 --> 00:31:27,219 the past few days. 749 00:31:27,319 --> 00:31:29,121 We're committed to helping her get... George. 750 00:31:29,221 --> 00:31:31,857 Hey. Taryn. 751 00:31:31,991 --> 00:31:34,160 How are you feeling this morning? 752 00:31:34,226 --> 00:31:36,328 Not too bad. 753 00:31:36,428 --> 00:31:38,130 Maybe a little better. 754 00:31:38,197 --> 00:31:40,532 MARY: Well, your vitals look good, Taryn. 755 00:31:40,632 --> 00:31:42,468 It's part of an encouraging trend. 756 00:31:42,534 --> 00:31:43,835 You should be going home soon. 757 00:31:43,902 --> 00:31:45,737 (chuckles) Oh, my God. (Relieved laugh) 758 00:31:45,871 --> 00:31:49,608 Looking at your chart, these look like typical treatments. 759 00:31:49,708 --> 00:31:51,978 Did Dr. Watson try anything new? 760 00:31:52,078 --> 00:31:53,879 Just the usual. 761 00:31:53,980 --> 00:31:55,781 T-The bully has a mind of its own. 762 00:31:55,881 --> 00:31:58,184 (laughing): If I get a good window, 763 00:31:58,284 --> 00:32:01,087 I don't ask too many questions. 764 00:32:01,220 --> 00:32:03,755 Well, I'll leave you two alone. 765 00:32:06,558 --> 00:32:09,395 You had a mole removal last week? 766 00:32:10,496 --> 00:32:11,964 Did Dr. Watson say why he'd do that 767 00:32:12,064 --> 00:32:14,000 in the middle of a sickle cell crisis? 768 00:32:14,900 --> 00:32:17,236 Uh, he was concerned about it. 769 00:32:17,369 --> 00:32:18,504 Uh... 770 00:32:18,570 --> 00:32:21,340 I'm not sure, Dr. Morstan. 771 00:32:21,407 --> 00:32:24,210 Maybe he just wanted to do something. 772 00:32:29,048 --> 00:32:32,118 How many mole removals have you done this year? 773 00:32:32,218 --> 00:32:33,919 I'm not sure. One. 774 00:32:34,020 --> 00:32:35,921 You've done one, and you did it last week 775 00:32:36,022 --> 00:32:37,256 while your patient was in the middle 776 00:32:37,356 --> 00:32:38,557 of a sickle cell crisis. 777 00:32:38,657 --> 00:32:39,925 Last year, none. 778 00:32:40,026 --> 00:32:41,860 The year before that, also none. 779 00:32:41,927 --> 00:32:43,262 So what are we talking? Moles? 780 00:32:43,362 --> 00:32:44,896 Taryn is going home today. 781 00:32:44,963 --> 00:32:46,332 That's great. 782 00:32:46,432 --> 00:32:47,799 That's not great? It's great 783 00:32:47,933 --> 00:32:49,535 if it happened in the normal course of business. 784 00:32:49,601 --> 00:32:51,337 Look, I'm a little confused. 785 00:32:51,437 --> 00:32:52,571 You come to me to stabilize a patient 786 00:32:52,638 --> 00:32:53,605 in the middle of a crisis. 787 00:32:53,739 --> 00:32:55,674 Taryn Quintyne is stable. 788 00:32:55,774 --> 00:32:56,842 So what are we talking about? 789 00:32:56,942 --> 00:32:58,944 Mm. We're talking about a procedure 790 00:32:59,045 --> 00:33:00,712 scheduled for no apparent reason. 791 00:33:00,812 --> 00:33:02,781 I was concerned about the shape and the spread of her mole. 792 00:33:02,881 --> 00:33:05,317 We're talking about a doctor with a huge ego 793 00:33:05,417 --> 00:33:07,219 and a TBI that could be compromising 794 00:33:07,319 --> 00:33:09,121 his executive function. Okay, I'm sorry. 795 00:33:09,255 --> 00:33:10,856 Whenever a patient needs special attention, 796 00:33:10,956 --> 00:33:12,924 I am the first one you come to see. 797 00:33:13,025 --> 00:33:16,028 When that patient improves, then suddenly it's suspicious? 798 00:33:16,128 --> 00:33:18,430 Is there anything you want to tell me, John? 799 00:33:18,497 --> 00:33:19,565 Yes. 800 00:33:19,631 --> 00:33:22,334 I'm glad Taryn is feeling better. 801 00:33:22,434 --> 00:33:24,270 (sighs) 802 00:33:24,370 --> 00:33:25,504 TARYN: What's this for, again? 803 00:33:25,637 --> 00:33:27,773 I gave a sample this morning. 804 00:33:27,873 --> 00:33:29,241 Just some extra tests. 805 00:33:29,308 --> 00:33:31,643 We'll have you out of here in no time, Taryn. 806 00:33:34,713 --> 00:33:36,515 Here you go, Dr. Morstan. 807 00:33:36,615 --> 00:33:38,084 Anything else you need? 808 00:33:38,184 --> 00:33:40,352 I've got it from here. Thanks. 809 00:33:45,624 --> 00:33:47,826 ♪ 810 00:33:56,668 --> 00:34:00,306 I understand one of the biggest challenges 811 00:34:00,406 --> 00:34:03,242 facing young companies is talent retention. 812 00:34:03,342 --> 00:34:05,277 You won't have that issue with me. 813 00:34:05,377 --> 00:34:07,846 I want to stay in one place and grow. 814 00:34:09,715 --> 00:34:11,717 Your credentials are impeccable. Mm-hmm. 815 00:34:11,817 --> 00:34:13,485 A magna cum laude graduate of CMU? 816 00:34:13,585 --> 00:34:16,588 Oh, come on. Why, thank you, fake hiring manager. 817 00:34:16,688 --> 00:34:19,257 I do see that you've had some short stints 818 00:34:19,324 --> 00:34:20,458 at a few companies. 819 00:34:20,559 --> 00:34:21,659 Care to comment on that? 820 00:34:21,793 --> 00:34:24,862 I had some health issues. 821 00:34:24,996 --> 00:34:27,132 That's all in the past, though. 822 00:34:27,199 --> 00:34:29,201 Well, I mean, you've handled yourself impeccably 823 00:34:29,335 --> 00:34:31,503 in this fake practice job interview. 824 00:34:31,637 --> 00:34:33,505 Uh... 825 00:34:33,605 --> 00:34:34,973 Should we have sex? 826 00:34:35,072 --> 00:34:36,442 (stammers) 827 00:34:36,542 --> 00:34:39,511 That's not how fake practice job interviews end. 828 00:34:39,610 --> 00:34:41,447 Not... usually. 829 00:34:41,547 --> 00:34:44,049 Fine. Well, give me a minute to take your credentials 830 00:34:44,150 --> 00:34:45,717 up the fake practice ladder, 831 00:34:45,851 --> 00:34:47,186 but in the meantime... 832 00:34:48,387 --> 00:34:50,489 here are my initial thoughts. 833 00:34:50,589 --> 00:34:52,491 Thank you, fake hiring manager. 834 00:34:52,591 --> 00:34:53,725 Now we can have sex. 835 00:34:53,824 --> 00:34:56,262 T-This is my office, ma'am. 836 00:34:56,362 --> 00:34:58,164 (gasps) 837 00:34:58,230 --> 00:34:59,565 You okay? Baby? 838 00:34:59,698 --> 00:35:01,400 (shallow breath, pained groan) 839 00:35:01,500 --> 00:35:03,402 Um... How bad is it? 840 00:35:03,535 --> 00:35:04,636 One to ten? 841 00:35:04,736 --> 00:35:06,538 It... This... That's not it. 842 00:35:06,638 --> 00:35:08,140 This is different. 843 00:35:08,207 --> 00:35:09,241 My chest... 844 00:35:09,375 --> 00:35:10,709 (straining) 845 00:35:10,809 --> 00:35:12,311 Call Dr. Watson. 846 00:35:12,378 --> 00:35:14,313 Patient is tachycardic, hypotensive. 847 00:35:14,380 --> 00:35:15,881 Start a Norepi drip at five mikes per minutes. 848 00:35:15,981 --> 00:35:18,083 Looks like she threw a pulmonary embolism. 849 00:35:18,184 --> 00:35:19,485 We need to confirm with CT-PE. 850 00:35:19,585 --> 00:35:20,952 WATSON: Page vascular surgery. 851 00:35:21,052 --> 00:35:23,422 She needs to get to the OR for an embolectomy. 852 00:35:23,522 --> 00:35:25,457 (monitors beeping steadily) 853 00:35:29,528 --> 00:35:30,729 There's another way to treat her. 854 00:35:30,829 --> 00:35:32,298 She needs surgery. 855 00:35:32,398 --> 00:35:33,599 Anti-clotting medication. 856 00:35:33,699 --> 00:35:35,467 It'll also leave less of A trail. 857 00:35:36,635 --> 00:35:38,970 In case anyone's wondering what caused the pulmonary embolism. 858 00:35:39,070 --> 00:35:40,606 You'll be covered. 859 00:35:40,706 --> 00:35:44,009 The base repair procedure, it's not responsible for this. 860 00:35:45,577 --> 00:35:46,812 It isn't. 861 00:35:46,912 --> 00:35:49,181 And I'm not thinking about covering my tracks. 862 00:35:49,281 --> 00:35:51,217 We have to figure out what caused this. 863 00:35:51,317 --> 00:35:52,984 STEPHENS: First things first. 864 00:35:53,084 --> 00:35:55,086 You say the base repair editing didn't cause. 865 00:35:55,221 --> 00:35:56,922 Taryn's pulmonary embolism, but what if you're wrong? 866 00:35:57,022 --> 00:35:58,156 I'm not wrong. 867 00:35:58,257 --> 00:35:59,558 Stop cutting me off. 868 00:35:59,625 --> 00:36:01,026 We can't have a differential 869 00:36:01,092 --> 00:36:02,928 while ignoring obvious potential explanations. 870 00:36:03,028 --> 00:36:04,463 The hole you drilled in her shin. 871 00:36:04,563 --> 00:36:06,432 If it dislodged fat cells from her bone marrow 872 00:36:06,532 --> 00:36:07,933 into the bloodstream, it could've caused... 873 00:36:08,033 --> 00:36:09,468 I believe the hole was clean. 874 00:36:09,601 --> 00:36:10,702 It's still an experimental procedure. 875 00:36:10,802 --> 00:36:12,037 If I caused this, 876 00:36:12,137 --> 00:36:13,639 there's nothing we can do about it now. 877 00:36:13,739 --> 00:36:15,441 I'll own it, I'll admit to it, 878 00:36:15,541 --> 00:36:16,908 and it won't touch any of you. 879 00:36:17,008 --> 00:36:19,211 But for five minutes, can you join me in a world 880 00:36:19,278 --> 00:36:20,746 where we help our patient? 881 00:36:20,846 --> 00:36:22,681 INGRID: She's been bedridden from sickle cell. 882 00:36:22,781 --> 00:36:24,683 Immobilization can trigger a PE. 883 00:36:24,783 --> 00:36:26,418 (sighs) 884 00:36:26,485 --> 00:36:29,288 Maybe, but Taryn's been bedridden before. 885 00:36:29,388 --> 00:36:31,923 They're closing. The patient's stable. 886 00:36:31,990 --> 00:36:33,058 (door closes) (sighs) 887 00:36:33,158 --> 00:36:34,460 Taryn has a copper IUD? 888 00:36:34,560 --> 00:36:36,628 A copper IUD can't cause a pulmonary embolism. 889 00:36:36,728 --> 00:36:38,129 WATSON: Yeah, that's true. 890 00:36:38,230 --> 00:36:41,567 But it might cause us to overlook something that could. 891 00:36:43,435 --> 00:36:45,371 You ruthless bitch. 892 00:36:45,471 --> 00:36:47,406 I don't like it when you call me that. 893 00:36:47,506 --> 00:36:48,740 Oh, no... 894 00:36:48,807 --> 00:36:50,509 I kind of love it, 895 00:36:50,609 --> 00:36:51,910 if I'm being honest. 896 00:36:52,010 --> 00:36:53,479 (laughs) 897 00:36:53,579 --> 00:36:56,348 The chairman told me you wrote a referral for Gigi Grigoryan? 898 00:36:56,482 --> 00:36:58,350 She got in. 899 00:36:59,184 --> 00:37:01,487 Can't believe you did that for me. 900 00:37:01,587 --> 00:37:04,290 SASHA: I saw how much you were struggling, and I just... 901 00:37:04,390 --> 00:37:07,493 Well, you left a file out on your desk, 902 00:37:07,626 --> 00:37:09,928 and a referral form, it was just right there. 903 00:37:10,028 --> 00:37:11,830 And, honestly, 904 00:37:11,930 --> 00:37:14,032 it was painful watching you flunk so hard. 905 00:37:14,165 --> 00:37:16,001 (chuckles) So you took over. 906 00:37:16,101 --> 00:37:18,036 Queen of the group projects. 907 00:37:18,136 --> 00:37:19,838 I should have known. 908 00:37:19,971 --> 00:37:21,740 A . See? 909 00:37:21,840 --> 00:37:23,174 Catch more flies with honey. 910 00:37:23,275 --> 00:37:25,176 Try, you catch more flies 911 00:37:25,311 --> 00:37:28,314 by being an overachieving, ruthless bitch. 912 00:37:28,414 --> 00:37:30,349 Thanks, Sasha. 913 00:37:30,482 --> 00:37:33,051 Um, I assume you didn't mention me? 914 00:37:33,184 --> 00:37:34,386 In my referral? 915 00:37:34,520 --> 00:37:36,488 Course not, in case the chairman does have 916 00:37:36,555 --> 00:37:39,157 something against you, now he'll never know you were 917 00:37:39,224 --> 00:37:40,492 the one who wanted her in. 918 00:37:40,559 --> 00:37:42,394 Perfect. 919 00:37:53,605 --> 00:37:55,507 How long have you been standing there? 920 00:37:55,574 --> 00:37:57,709 A little while. 921 00:38:01,212 --> 00:38:04,015 I drew three vials of blood 922 00:38:04,082 --> 00:38:06,952 from Taryn Quintyne when she was here. 923 00:38:07,052 --> 00:38:09,220 I haven't sent it to the lab yet, 924 00:38:09,355 --> 00:38:11,056 but when I do... 925 00:38:11,156 --> 00:38:14,159 I suspect that I will see fewer and fewer sickle cells 926 00:38:14,225 --> 00:38:15,861 with each sample. 927 00:38:15,927 --> 00:38:17,262 If I see that, 928 00:38:17,396 --> 00:38:20,031 I'll start asking questions about that mole removal. 929 00:38:20,098 --> 00:38:22,000 You know I'll get to the truth. 930 00:38:22,968 --> 00:38:24,403 What do you think the truth is? 931 00:38:24,503 --> 00:38:26,071 Did you go around the FDA? 932 00:38:26,171 --> 00:38:28,239 Did you do a procedure 933 00:38:28,374 --> 00:38:31,510 that gave Taryn Quintyne a life-threatening embolism? 934 00:38:31,577 --> 00:38:34,613 You sent me a dying patient. 935 00:38:35,581 --> 00:38:38,350 She might not have given up this year, or maybe even next year, 936 00:38:38,417 --> 00:38:41,720 but Taryn Quintyne was dying. 937 00:38:41,820 --> 00:38:43,254 We can fix the problem. 938 00:38:43,389 --> 00:38:45,857 A cure exists, but instead of giving it to her, 939 00:38:45,957 --> 00:38:48,594 it's sitting on some shelf that she can't reach. 940 00:38:48,694 --> 00:38:51,262 A shelf that no one from Stanton Heights, 941 00:38:51,363 --> 00:38:54,099 or Homewood, or Wilkinsburg, or anywhere can reach. 942 00:38:54,199 --> 00:38:56,201 I don't need a speech, John, I just need the truth. 943 00:38:56,301 --> 00:38:57,636 Well, the truth 944 00:38:57,769 --> 00:39:00,639 is that there's a perfectly logical explanation 945 00:39:00,772 --> 00:39:02,974 for Taryn's pulmonary embolism. 946 00:39:03,074 --> 00:39:06,311 It has nothing to do with any type of secret procedures, 947 00:39:06,412 --> 00:39:08,980 or anything else like that. 948 00:39:12,451 --> 00:39:14,486 How did we miss this? 949 00:39:14,620 --> 00:39:16,888 I can tell you all about that. 950 00:39:16,988 --> 00:39:19,257 But first, you have a decision to make. 951 00:39:19,324 --> 00:39:23,228 I can tell the truth to you, or anyone else who asks. 952 00:39:23,294 --> 00:39:24,663 Or you can deliver those test results 953 00:39:24,796 --> 00:39:26,898 to your thriving patient. 954 00:39:26,965 --> 00:39:28,767 (sighs) 955 00:39:29,668 --> 00:39:32,337 (crowd clapping) 956 00:39:34,172 --> 00:39:36,274 You don't get to five years by gritting your teeth 957 00:39:36,374 --> 00:39:37,976 and going it alone. 958 00:39:39,310 --> 00:39:41,079 You don't get to six months that way. 959 00:39:41,880 --> 00:39:44,382 Or 90 days or 30 days. 960 00:39:46,618 --> 00:39:48,420 We do this together. 961 00:39:49,187 --> 00:39:52,323 "We are like the passengers of a great liner... 962 00:39:53,258 --> 00:39:55,727 "the moment after rescue from shipwreck 963 00:39:55,827 --> 00:39:57,996 "when camaraderie, 964 00:39:58,096 --> 00:40:00,499 "joyousness and democracy pervade the vessel 965 00:40:00,599 --> 00:40:03,268 from steerage to Captain's table." 966 00:40:13,812 --> 00:40:15,547 WOMAN'S VOICE: Dinner's ready! 967 00:40:15,681 --> 00:40:17,348 Ten minutes. 968 00:40:19,518 --> 00:40:21,352 Ingrid, come on. 969 00:40:21,487 --> 00:40:22,988 It's Mom's birthday. 970 00:40:23,088 --> 00:40:24,756 Mom's been gone 20 years, Gigi. 971 00:40:24,856 --> 00:40:27,392 I'm sure she won't mind if we eat a little late. 972 00:40:30,161 --> 00:40:32,263 (chuckles) 973 00:40:33,899 --> 00:40:35,400 Fine. 974 00:40:35,501 --> 00:40:38,036 Let me just finish this last thought. 975 00:40:48,313 --> 00:40:50,148 (sighs) 976 00:40:52,884 --> 00:40:54,620 I'm sorry, Gigi. 977 00:40:54,720 --> 00:40:56,287 It's okay. 978 00:40:56,387 --> 00:40:58,323 This can't be right. 979 00:40:58,423 --> 00:40:59,825 It's right, Taryn. 980 00:40:59,891 --> 00:41:01,059 We double-checked. 981 00:41:01,192 --> 00:41:02,661 You're pregnant. 982 00:41:02,728 --> 00:41:04,462 But I have an IUD. 983 00:41:04,563 --> 00:41:06,965 That's why we didn't think to test you earlier. 984 00:41:07,065 --> 00:41:09,601 IUDs have a one-percent failure rate. 985 00:41:09,735 --> 00:41:12,470 You got... I want to say "lucky," 986 00:41:12,571 --> 00:41:14,706 but I'll follow your lead. 987 00:41:15,907 --> 00:41:17,776 This is why I had the embolism? 988 00:41:17,909 --> 00:41:19,044 It seems so. 989 00:41:19,144 --> 00:41:20,579 It happens. 990 00:41:20,712 --> 00:41:23,281 Pregnancy is a hypercoagulable state. 991 00:41:26,284 --> 00:41:28,119 Are you okay? 992 00:41:28,219 --> 00:41:31,723 I'm so much better than okay. 993 00:41:33,291 --> 00:41:35,861 My body? 994 00:41:35,927 --> 00:41:38,429 It is so beat up. 995 00:41:40,165 --> 00:41:42,568 I got an IUD because... 996 00:41:42,634 --> 00:41:45,336 I gave up hope a long time ago. 997 00:41:45,436 --> 00:41:46,872 (Taryn sobs) 998 00:41:46,972 --> 00:41:48,073 (chuckles softly) 999 00:41:48,173 --> 00:41:50,408 I need to call George. 1000 00:41:50,508 --> 00:41:52,878 Can I, uh... Should I...? 1001 00:41:52,978 --> 00:41:54,646 Can I have this baby? 1002 00:41:54,780 --> 00:41:56,147 You're okay. 1003 00:41:56,281 --> 00:41:58,449 Now, if you would've gotten the existing cure, 1004 00:41:58,584 --> 00:42:01,086 the stem cell ablation may have sterilized you forever. 1005 00:42:01,186 --> 00:42:03,655 Now, however it happened, 1006 00:42:03,755 --> 00:42:05,123 you're feeling better. 1007 00:42:05,256 --> 00:42:07,458 You have every reason to be hopeful, Taryn. 1008 00:42:07,559 --> 00:42:10,796 Tell your boyfriend you're gonna have a baby. 1009 00:42:10,896 --> 00:42:12,063 (laughs) 1010 00:42:12,163 --> 00:42:13,565 Congratulations. 1011 00:42:13,665 --> 00:42:16,635 Thank you, Dr. Morstan. 1012 00:42:17,603 --> 00:42:19,004 Thank you. 1013 00:42:22,774 --> 00:42:25,543 (breathes deeply) 1014 00:42:43,428 --> 00:42:45,196 Captioning sponsored by CBS. 1015 00:42:45,330 --> 00:42:47,733 Captioned by Media Access Group at WGBH access.wgbh.org