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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:06,250 --> 00:00:11,400 Victim is Mr Arnie Rahul. Consultant surgeon. 48 years of age. 2 00:00:11,500 --> 00:00:14,200 Good reputation, though he's fallen out with a few people recently. 3 00:00:14,201 --> 00:00:16,301 He was about to start an operation. He gets a phone call. 4 00:00:16,320 --> 00:00:18,820 Walks out, never comes back. 5 00:00:19,520 --> 00:00:22,040 Single puncture wound to the left chest wall. 6 00:00:23,240 --> 00:00:26,040 What's that in his hand? Looks like a syringe and needle. 7 00:00:26,040 --> 00:00:29,280 It's a Hickman line. A long-term vascular access device 8 00:00:29,280 --> 00:00:31,800 for people who need chemotherapy or blood transfusions. 9 00:00:31,800 --> 00:00:34,520 The assailant would have had extensive cross contamination 10 00:00:34,520 --> 00:00:36,000 with the victim's blood. 11 00:00:36,000 --> 00:00:38,160 Stick that in to a big artery and blood will flow out 12 00:00:38,160 --> 00:00:39,720 like a high-pressure hose. 13 00:00:39,720 --> 00:00:41,080 Simi Jacobs. 14 00:00:42,160 --> 00:00:43,520 He's denying everything. 15 00:00:44,600 --> 00:00:47,840 Simi Jacobs is not a match 16 00:00:47,840 --> 00:00:49,480 to the blood spatter at the scene. 17 00:00:49,480 --> 00:00:51,760 So, who is it? It's Wilfred Okoye. 18 00:00:51,760 --> 00:00:52,880 The patient? 19 00:00:52,880 --> 00:00:56,640 Arnie Rahul was murdered by a man who was under general anaesthetic 20 00:00:56,640 --> 00:00:58,040 in a different room? 21 00:00:58,040 --> 00:01:01,680 Blood alcohol level, three times the legal driving limit. 22 00:01:01,680 --> 00:01:04,000 You said he shouldn't be operating. 23 00:01:04,000 --> 00:01:06,000 Not after the Harry Fletcher incident. 24 00:01:06,000 --> 00:01:08,920 Arrested on the table during surgery last week. 25 00:01:08,920 --> 00:01:11,560 I want you to do the postmortem. 26 00:01:11,560 --> 00:01:13,760 Technically that would be a conflict of interest. 27 00:01:13,760 --> 00:01:17,040 Summarising postmortem examination, Harry Fletcher. 28 00:01:17,040 --> 00:01:18,960 What are you doing? My colleagues are here. 29 00:01:18,960 --> 00:01:21,920 Is that Emily Braithwaite? She's Adam's godmother. 30 00:01:21,920 --> 00:01:24,040 You'd think he might have mentioned it. 31 00:01:24,040 --> 00:01:26,560 Are you going to confront him? Not yet. 32 00:01:26,560 --> 00:01:29,000 Your original stem cell work was brilliant. 33 00:01:29,000 --> 00:01:32,880 But you tried and failed to turn it into a viable cancer treatment. 34 00:01:32,880 --> 00:01:35,440 Wilfred Okoye, still in the hospital. 35 00:01:35,440 --> 00:01:37,120 What's he going to know? 36 00:01:37,120 --> 00:01:40,080 You won't find out unless you ask him. 37 00:01:40,080 --> 00:01:42,960 Mr Fletcher died because of surgical error. 38 00:01:42,960 --> 00:01:46,520 Adam! You have no idea what you've done. 39 00:01:46,520 --> 00:01:49,040 When I applied for this job I falsified my CV, 40 00:01:49,040 --> 00:01:50,920 and Emily Braithwaite tried to use this 41 00:01:50,920 --> 00:01:53,200 fact to influence my findings in the Fletcher Case. 42 00:01:53,200 --> 00:01:54,880 Here's my letter of resignation. 43 00:01:54,880 --> 00:01:56,160 Effective immediately. 44 00:01:57,680 --> 00:02:03,720 Testator silens 45 00:02:06,240 --> 00:02:13,400 Costestes e spiritu 46 00:02:13,400 --> 00:02:20,880 Silencium 47 00:02:28,200 --> 00:02:34,000 Testator silens. 48 00:02:40,120 --> 00:02:42,720 DISTANT SIREN 49 00:02:45,520 --> 00:02:49,080 Wilfred Okoye, a Beninese farm worker, was admitted 50 00:02:49,080 --> 00:02:53,240 to St Jude's hospital for the treatment of leukaemia a week ago. 51 00:02:53,240 --> 00:02:56,640 Although he lost consciousness briefly during the attack 52 00:02:56,640 --> 00:03:00,320 on his life last night, he seems to have recovered with no ill effects. 53 00:03:00,320 --> 00:03:04,640 Awaiting toxicology from the syringe we believe was used in the attack. 54 00:03:04,640 --> 00:03:06,400 Prints? Fibres? 55 00:03:06,400 --> 00:03:08,680 Nothing conclusive. We're interviewing witnesses 56 00:03:08,680 --> 00:03:10,840 but no-one got a good look at the attacker. 57 00:03:10,840 --> 00:03:13,360 How come he's being treated here in the UK? 58 00:03:13,360 --> 00:03:17,200 It was set up by a charity, and then arranged through Rahul. 59 00:03:18,800 --> 00:03:23,040 Here is a man who has lived his entire life in Benin 60 00:03:23,040 --> 00:03:27,240 up until a week ago, and, according to our DNA evidence, 61 00:03:27,240 --> 00:03:31,520 murders his surgeon while under anaesthetic in a different room. 62 00:03:35,120 --> 00:03:40,720 Could the DNA at the murder scene been a contaminant or planted? 63 00:03:40,720 --> 00:03:43,480 No. The spatter patterns are too perfect. 64 00:03:43,480 --> 00:03:45,840 It came from someone who was in the room at the time. 65 00:03:45,840 --> 00:03:47,480 So, how do you explain it? 66 00:03:50,800 --> 00:03:53,880 How do we know Wilfred was anaesthetised? 67 00:03:53,880 --> 00:03:56,680 I mean, how do we know it was him? 68 00:03:56,680 --> 00:03:58,320 What, he's got an identical twin? 69 00:03:58,320 --> 00:03:59,800 Bit fantastical, Steve. 70 00:03:59,800 --> 00:04:01,640 I don't know. 71 00:04:01,640 --> 00:04:03,240 There's another explanation. 72 00:04:05,320 --> 00:04:07,440 DNA samples got mixed up. 73 00:04:07,440 --> 00:04:09,440 Ah! No way! 74 00:04:09,440 --> 00:04:12,640 Look, I'm just putting it out there. Mm-mn. We could run the test again. 75 00:04:12,640 --> 00:04:14,640 Those samples were handled correctly. 76 00:04:16,080 --> 00:04:18,280 Jack, shall we just run them again? 77 00:04:21,560 --> 00:04:23,320 Right, yep. Good. 78 00:04:24,560 --> 00:04:25,600 OK. 79 00:04:26,720 --> 00:04:28,720 Let me know when toxicology comes back. 80 00:04:37,040 --> 00:04:40,520 So, the samples got mixed up, did they? It's always possible. 81 00:04:40,520 --> 00:04:41,560 Mm-hm. 82 00:04:42,560 --> 00:04:45,800 You know who took the swab from Simi Jacobs. Adam. 83 00:04:47,240 --> 00:04:48,560 What are you suggesting? 84 00:04:50,600 --> 00:04:52,080 Just saying. 85 00:04:58,560 --> 00:05:00,840 PHONE RINGS 86 00:05:00,840 --> 00:05:02,640 VOICEMAIL: You have reached Dr Adam Yuen. 87 00:05:02,640 --> 00:05:04,240 I am unable to take your call. 88 00:05:04,240 --> 00:05:06,200 Please leave a message after the tone. 89 00:05:09,000 --> 00:05:11,560 Do you know what I don't understand? 90 00:05:11,560 --> 00:05:13,760 It was just a six-month placement, 91 00:05:13,760 --> 00:05:16,400 and his CV is impressive enough without it. 92 00:05:16,400 --> 00:05:19,560 So, why did he risk his career and lie about it? 93 00:05:22,520 --> 00:05:24,840 Has he lied about anything else? 94 00:05:24,840 --> 00:05:27,360 Everything else checks out. 95 00:05:27,360 --> 00:05:28,840 Are you sure about that? 96 00:05:32,280 --> 00:05:35,960 You have an injury over your left eye and a wound on your neck. 97 00:05:37,440 --> 00:05:39,400 How do you account for them, Simi? 98 00:05:40,640 --> 00:05:42,120 Yeah, I got mugged. 99 00:05:42,120 --> 00:05:44,560 A kid with a knife. Really? 100 00:05:46,320 --> 00:05:48,600 And did you report the assault? 101 00:05:48,600 --> 00:05:51,160 No. Why not? 102 00:05:51,160 --> 00:05:52,760 What, are you going to catch him? 103 00:05:54,920 --> 00:05:58,240 He's answered your questions, so unless you have other evidence? 104 00:06:11,680 --> 00:06:13,520 PHONE PINGS 105 00:06:21,480 --> 00:06:24,880 Tox results from the syringe used in the attack on Wilfred. 106 00:06:24,880 --> 00:06:26,640 Here we go. Let's have a look. 107 00:06:31,760 --> 00:06:33,960 That's it? Midazolam? 108 00:06:36,200 --> 00:06:38,400 That's a sedative, isn't it? 109 00:06:38,400 --> 00:06:39,440 Yeah. 110 00:06:41,600 --> 00:06:45,680 The full syringe would have had about five milligrams in it. 111 00:06:45,680 --> 00:06:46,800 That's not very much. 112 00:06:47,840 --> 00:06:51,920 So, either the assailant is incompetent, 113 00:06:51,920 --> 00:06:54,200 or this wasn't intended to kill him. 114 00:06:55,720 --> 00:06:58,600 So, what's the aim? 115 00:06:58,600 --> 00:07:00,240 Kidnapping? 116 00:07:03,000 --> 00:07:05,080 HE SIGHS 117 00:07:05,080 --> 00:07:07,200 The guy's already ill. 118 00:07:07,200 --> 00:07:09,520 You know... 119 00:07:09,520 --> 00:07:13,480 If someone wanted him dead, it's not going to be that hard, is it? 120 00:07:13,480 --> 00:07:14,800 He's got leukaemia. 121 00:07:16,640 --> 00:07:19,400 It would look like natural causes if he died of sepsis. 122 00:07:21,960 --> 00:07:24,960 Should I get that syringe tested again for bacteria? 123 00:07:31,720 --> 00:07:34,320 What's this about Mr Okoye being moved? 124 00:07:34,320 --> 00:07:35,760 It's for his own safety. 125 00:07:35,760 --> 00:07:38,440 To the Cowley Institute? And who's paying for that? 126 00:07:38,440 --> 00:07:41,400 Oh, I've been assured that they have all the facilities required, 127 00:07:41,400 --> 00:07:44,160 and they've offered to do the treatment free of charge. 128 00:07:44,160 --> 00:07:45,560 I will not allow it. 129 00:07:45,560 --> 00:07:48,800 Someone in your hospital is trying to kill Mr Okoye. 130 00:07:50,320 --> 00:07:53,480 Quite frankly, Dr Braithwaite, I don't need your permission. 131 00:08:06,080 --> 00:08:07,360 Haematology lab. 132 00:08:08,760 --> 00:08:10,760 Dr Braithwaite here. 133 00:08:10,760 --> 00:08:15,560 Wilfred Okoye, hospital number 1187266. 134 00:08:15,560 --> 00:08:18,080 I want all his stored blood and marrow samples sent 135 00:08:18,080 --> 00:08:19,720 to my office immediately. 136 00:08:46,880 --> 00:08:49,000 Finished! 137 00:08:49,000 --> 00:08:53,760 79 needles swabbed and ready to go. 138 00:08:55,320 --> 00:08:57,680 You've got to see this. 139 00:08:57,680 --> 00:08:59,680 Microbiology results from the syringe 140 00:08:59,680 --> 00:09:01,920 used in the attack on Wilfred. 141 00:09:01,920 --> 00:09:05,160 Turns out it is full of bacteria - E coli. 142 00:09:06,920 --> 00:09:09,080 Well, it was lying around on the floor. 143 00:09:09,080 --> 00:09:10,360 Could it be a contaminant? 144 00:09:10,360 --> 00:09:13,040 No. It's a pure growth - just one type of bug in there. 145 00:09:13,040 --> 00:09:14,920 If it was a contaminant you'd expect to see 146 00:09:14,920 --> 00:09:16,680 lots of different organisms. 147 00:09:16,680 --> 00:09:18,320 It's been created deliberately. 148 00:09:19,560 --> 00:09:23,320 So, what? The killer sneaks into Wilfred's room pretending 149 00:09:23,320 --> 00:09:26,880 to be a nurse, inoculates him with the bacteria, 150 00:09:26,880 --> 00:09:28,240 but adds a mild sedative... 151 00:09:30,440 --> 00:09:33,280 ..so that when the real nurse comes in with his medication, 152 00:09:33,280 --> 00:09:36,880 he's asleep and can't tell her that someone else has already been in. 153 00:09:38,080 --> 00:09:39,800 He gets sepsis, he dies. 154 00:09:39,800 --> 00:09:41,280 Looks like natural causes. 155 00:09:42,840 --> 00:09:44,560 I need to tell DI Cracknell. 156 00:09:44,560 --> 00:09:47,160 You need to tell the doctors looking after Wilfred. 157 00:09:51,320 --> 00:09:55,520 HEART MONITOR BEEPS 158 00:09:56,760 --> 00:09:58,960 HE BREATHES RAPIDLY 159 00:10:01,560 --> 00:10:04,200 ALARM SOUNDS 160 00:10:09,640 --> 00:10:11,520 HEART MONITOR BEEPS RAPIDLY 161 00:10:14,840 --> 00:10:16,960 HEART MONITOR FLATLINES 162 00:10:40,440 --> 00:10:43,360 It's as we expected - extensive peripheral oedema, 163 00:10:43,360 --> 00:10:46,680 multiple organ failure, consistent with sepsis. 164 00:10:46,680 --> 00:10:50,680 Yep. Toxicology shows only medications used for his treatment, 165 00:10:50,680 --> 00:10:54,160 antibiotics, ceftriaxone, gentamicin present 166 00:10:54,160 --> 00:10:55,880 in therapeutic concentrations. 167 00:10:55,880 --> 00:10:59,240 So, cause of death is consistent with deliberate inoculation 168 00:10:59,240 --> 00:11:02,120 of the culture of E coli, on a background 169 00:11:02,120 --> 00:11:05,520 of chemotherapy-induced immune compromise. 170 00:11:05,520 --> 00:11:08,640 Well, we've got no other leads on his attacker at present. 171 00:11:08,640 --> 00:11:11,040 We're liaising with the Beninese Consulate to inform 172 00:11:11,040 --> 00:11:13,640 the family of the deceased. 173 00:11:13,640 --> 00:11:19,000 DNA says Wilfred Okoye was guilty of Rahul's murder, 174 00:11:19,000 --> 00:11:21,360 but being unconscious, had the perfect alibi. 175 00:11:23,040 --> 00:11:26,040 When a murder suspect gets murdered, what does that mean? 176 00:11:26,040 --> 00:11:27,760 Framed by the real murderer? 177 00:11:27,760 --> 00:11:30,360 Why would you frame someone with the perfect alibi? 178 00:11:36,560 --> 00:11:38,760 Simi Jacobs. 179 00:11:38,760 --> 00:11:40,440 What's his home address? 180 00:11:40,440 --> 00:11:41,480 Erm... 181 00:11:43,320 --> 00:11:47,080 Let's see. Flat 32, Bardwell House, Lincoln Street. 182 00:11:47,080 --> 00:11:50,720 Thought so. Okoye and Jacobs have been living together. 183 00:11:50,720 --> 00:11:53,920 Simi Jacobs has already been released, guv. 184 00:11:53,920 --> 00:11:56,520 What? Yeah. Lack of forensics. 185 00:11:56,520 --> 00:11:58,000 All right. 186 00:11:58,000 --> 00:12:00,000 Might I suggest we pick him up again? 187 00:12:07,160 --> 00:12:09,240 It still doesn't get us anywhere. 188 00:12:09,240 --> 00:12:11,000 It doesn't explain the DNA. 189 00:12:11,000 --> 00:12:13,400 And Simi was in custody when Wilfred was attacked, 190 00:12:13,400 --> 00:12:14,800 so it doesn't even explain that. 191 00:12:14,800 --> 00:12:17,280 We're just going round in circles. Yep. 192 00:12:28,160 --> 00:12:31,320 When he was interviewed, Wilfred said his leukaemia 193 00:12:31,320 --> 00:12:34,000 was common in his region. 194 00:12:36,640 --> 00:12:38,000 Doesn't sound right to me. 195 00:12:52,960 --> 00:12:54,840 PHONE RINGS 196 00:12:54,840 --> 00:12:56,880 VOICEMAIL: You have reached Dr Adam Yuen. 197 00:12:56,880 --> 00:12:58,320 I am unable to take your call. 198 00:12:58,320 --> 00:13:00,280 Please leave a message after the tone. 199 00:13:03,200 --> 00:13:05,160 Wait there. He's not in, guv. 200 00:13:05,160 --> 00:13:06,840 And the neighbours haven't seen him. 201 00:13:06,840 --> 00:13:09,120 He's not been seen back at work at the hospital either. 202 00:13:09,120 --> 00:13:12,000 You two stick around in case he comes back. 203 00:13:12,000 --> 00:13:15,240 I'm sorry, guv. I should have spotted the address. 204 00:13:17,040 --> 00:13:19,000 Don't worry about it. 205 00:13:19,000 --> 00:13:22,160 At least you didn't wrongly arrest a bereaved cancer patient. 206 00:13:26,520 --> 00:13:28,040 I'll do that next time. 207 00:13:32,360 --> 00:13:33,400 Bye. 208 00:13:38,360 --> 00:13:40,600 Nine missed calls. You're very persistent. 209 00:13:43,600 --> 00:13:45,240 I didn't want to end it like that. 210 00:13:47,880 --> 00:13:49,560 Can I help? 211 00:14:00,560 --> 00:14:03,600 You should have told me that Emily Braithwaite is your godmother. 212 00:14:03,600 --> 00:14:05,520 Some godmother. 213 00:14:05,520 --> 00:14:08,120 No doubt you've received the incriminating evidence about me. 214 00:14:08,120 --> 00:14:09,320 What evidence? 215 00:14:10,960 --> 00:14:13,720 She never sent it. I should have guessed. 216 00:14:13,720 --> 00:14:16,880 If she tried to blackmail you, then we'll make her answer for that. 217 00:14:16,880 --> 00:14:18,000 She's far too clever. 218 00:14:19,960 --> 00:14:22,880 Why do I think there's more to this than you're telling me? 219 00:14:24,600 --> 00:14:26,840 No, I just lied to advance my career. 220 00:14:26,840 --> 00:14:29,880 Really? Just to say you had a fellowship. Why would you do that? 221 00:14:35,440 --> 00:14:36,960 My family are all doctors. 222 00:14:36,960 --> 00:14:38,960 I was always going to be a surgeon. 223 00:14:38,960 --> 00:14:40,680 It was more or less decided for me. 224 00:14:42,560 --> 00:14:45,680 Final year of medical school, I was walking to uni 225 00:14:45,680 --> 00:14:48,920 and a cyclist is knocked off her bike, right in front of me. 226 00:14:48,920 --> 00:14:50,760 Now, I was a keen student. 227 00:14:50,760 --> 00:14:53,840 I used to carry a first aid kit around with me. 228 00:14:53,840 --> 00:14:57,520 If I'm honest, I was always waiting for something like this. 229 00:14:57,520 --> 00:15:00,920 When I think about that it's actually what I'm most ashamed of. 230 00:15:00,920 --> 00:15:03,200 She had facial injuries. 231 00:15:03,200 --> 00:15:05,840 Heavy, laboured breathing. She was losing consciousness fast. 232 00:15:05,840 --> 00:15:07,760 So, I thought, "She's suffocating. 233 00:15:07,760 --> 00:15:12,120 "She needs a surgical airway, a cricothyroidotomy." 234 00:15:12,120 --> 00:15:13,480 So, I made my incision. 235 00:15:13,480 --> 00:15:16,000 Something that I had practised on mannequins. 236 00:15:16,000 --> 00:15:20,160 What I didn't know is that she had an abnormal anatomy - 237 00:15:20,160 --> 00:15:23,600 an aberrant subclavian artery, looping high in the neck. 238 00:15:24,760 --> 00:15:28,080 It's present in 1% of people and 0% of mannequins. 239 00:15:28,080 --> 00:15:30,480 How could you have known? It was a bloodbath. 240 00:15:38,160 --> 00:15:41,000 The artery retracted back into her chest. 241 00:15:41,000 --> 00:15:43,600 There was nothing we could do to save her. 242 00:15:43,600 --> 00:15:45,760 She bled to death in minutes. 243 00:15:50,200 --> 00:15:52,720 My father was furious. 244 00:15:54,400 --> 00:15:57,080 Not because I stupidly tried a tracheostomy 245 00:15:57,080 --> 00:15:58,840 and killed an innocent young girl. 246 00:16:00,440 --> 00:16:04,240 But because I didn't study hard enough to do it competently. 247 00:16:06,480 --> 00:16:10,960 So, he used his influence and arranged for my fellowship 248 00:16:10,960 --> 00:16:12,720 as cover. For what? 249 00:16:16,640 --> 00:16:18,120 For my absence. 250 00:16:21,440 --> 00:16:24,720 It took months of therapy before I could even leave the house. 251 00:16:33,480 --> 00:16:37,080 The irony in all of this is that the one who helped me out 252 00:16:37,080 --> 00:16:38,760 the most was Emily Braithwaite. 253 00:16:40,200 --> 00:16:42,800 She visited me more often than my parents. 254 00:16:45,840 --> 00:16:47,080 She understood. 255 00:16:50,000 --> 00:16:52,320 But there was no way I was going to be a surgeon. 256 00:16:56,000 --> 00:16:58,640 So, I decided to choose pathology, 257 00:16:58,640 --> 00:17:02,520 and a false narrative was created as to why I made the switch. 258 00:17:04,200 --> 00:17:07,120 When you start lying, 259 00:17:07,120 --> 00:17:09,400 you have to keep lying. 260 00:17:29,200 --> 00:17:31,240 Jack. Mm? I need to talk to you. 261 00:17:31,240 --> 00:17:32,600 Sure, what's up...? 262 00:17:35,120 --> 00:17:36,520 Hi. 263 00:17:36,520 --> 00:17:37,640 Are you kidding me? 264 00:17:41,000 --> 00:17:43,360 He doesn't work here any more because he lied to us, do you 265 00:17:43,360 --> 00:17:46,080 remember? Do you remember that? Adam's got a theory about Wilfred. 266 00:17:46,080 --> 00:17:47,640 Oh, right. Just hear him out. 267 00:17:47,640 --> 00:17:51,640 So, um, I just have to trust him now? 268 00:17:51,640 --> 00:17:53,640 No, you've got to trust me. 269 00:17:57,520 --> 00:17:58,640 Think about it. 270 00:17:59,960 --> 00:18:02,600 Why would someone want Wilfred dead? 271 00:18:02,600 --> 00:18:04,880 What did he know that was such a threat that someone 272 00:18:04,880 --> 00:18:05,920 had to kill him? 273 00:18:07,560 --> 00:18:11,000 Wilfred was being treated for acute myeloid leukaemia. 274 00:18:11,000 --> 00:18:12,240 That's rare. 275 00:18:12,240 --> 00:18:14,760 Remember, he said there were lots of other cases in his small 276 00:18:14,760 --> 00:18:16,960 village in Africa. 277 00:18:16,960 --> 00:18:19,680 What if Wilfred wasn't killed because of what he knew? 278 00:18:19,680 --> 00:18:20,840 Don't follow. 279 00:18:20,840 --> 00:18:22,640 Wilfred wasn't the witness. 280 00:18:24,800 --> 00:18:26,120 He was the evidence. 281 00:18:29,600 --> 00:18:32,000 This is a trephine biopsy of the bone marrow. 282 00:18:32,000 --> 00:18:35,720 We take a thin core of bone with marrow cells in it. 283 00:18:35,720 --> 00:18:38,040 I've already taken an aspirate of the fluids. 284 00:18:49,280 --> 00:18:52,760 So, the question is, why would so many people from one place 285 00:18:52,760 --> 00:18:54,160 all get leukaemia? 286 00:18:55,400 --> 00:18:57,240 And that's going to tell you, is it? 287 00:18:57,240 --> 00:18:59,080 To be honest, I've never done this before. 288 00:18:59,080 --> 00:19:01,080 Not postmortem, anyway. 289 00:19:01,080 --> 00:19:04,240 But you know what? It's crazy enough for it to work. Mm-mm. 290 00:19:16,000 --> 00:19:17,040 Thanks. 291 00:19:19,080 --> 00:19:22,440 Oh, look. Here's a billion DNA results from the needles. 292 00:19:24,040 --> 00:19:27,000 Want to give me a hand going through these? 293 00:19:27,000 --> 00:19:28,160 Didn't think so. 294 00:19:46,160 --> 00:19:48,840 Nikki? The slide's ready when you want to have a look. 295 00:19:57,240 --> 00:19:59,880 Good yield of cells. More than I expected. 296 00:19:59,880 --> 00:20:02,320 Definitely acute myeloid leukaemia. 297 00:20:02,320 --> 00:20:05,800 It's not typical. Looks more like secondary AML. 298 00:20:05,800 --> 00:20:08,520 Secondary to what? A toxin of some sort. 299 00:20:08,520 --> 00:20:10,560 Some industrial chemical, for example, 300 00:20:10,560 --> 00:20:14,560 or chemotherapy for a different cancer. 301 00:20:14,560 --> 00:20:17,440 Right. And that can occur years after the original exposure. 302 00:20:17,440 --> 00:20:19,440 Decades, in some cases. 303 00:20:19,440 --> 00:20:23,000 So, there may be other victims, all exposed to the same thing? 304 00:20:25,040 --> 00:20:26,400 Makes sense. 305 00:20:28,080 --> 00:20:32,120 BUZZING 306 00:20:45,280 --> 00:20:46,440 Can I help you? 307 00:20:46,440 --> 00:20:48,480 They told me Wilfred is here. 308 00:20:48,480 --> 00:20:50,320 Can I see him, yeah? 309 00:20:50,320 --> 00:20:52,520 Er, you are? Family. 310 00:20:54,800 --> 00:20:56,360 Do you want to take a seat? 311 00:20:56,360 --> 00:20:59,560 Will I be able to sit with him for a bit or...? I'll just check. 312 00:21:09,040 --> 00:21:11,360 I've found Rahul's murder weapon. 313 00:21:11,360 --> 00:21:15,120 One DNA profile matching Rahul, one matching Wilfred, 314 00:21:15,120 --> 00:21:16,880 just like we found at the scene. 315 00:21:16,880 --> 00:21:18,880 But there's a third profile. 316 00:21:20,640 --> 00:21:22,760 Yep. Simi Jacobs. 317 00:21:22,760 --> 00:21:24,800 Simi? He's here! 318 00:21:24,800 --> 00:21:27,720 What do you mean he's here? He wants to see Wilfred's body. 319 00:21:42,800 --> 00:21:45,600 This places Simi at the scene of Rahul's murder. 320 00:21:45,600 --> 00:21:47,600 We need to keep him here. 321 00:21:47,600 --> 00:21:49,200 Call DI Cracknell. 322 00:21:53,080 --> 00:21:55,600 So, hang on. Simi Jacobs just turned up at the lab. 323 00:21:55,600 --> 00:21:57,760 One needle injected into three people. 324 00:21:57,760 --> 00:21:59,200 Better get down here. 325 00:21:59,200 --> 00:22:01,200 Simi had a puncture wound to his neck. 326 00:22:01,200 --> 00:22:04,160 Rahul was stabbed in the chest, but Wilfred? 327 00:22:04,160 --> 00:22:05,960 And if Simi got in a fight with Rahul, 328 00:22:05,960 --> 00:22:07,920 why is Wilfred's blood spattered? 329 00:22:07,920 --> 00:22:10,600 Wilfred would have to have been in the room as well. 330 00:22:10,600 --> 00:22:12,600 Maybe he was. Genetically speaking. 331 00:22:13,920 --> 00:22:16,440 What if that needle only stabbed two people? 332 00:22:16,440 --> 00:22:19,320 Then one of them has two different types of DNA. Exactly. 333 00:22:19,320 --> 00:22:20,880 Huh? No, for that to work, it would 334 00:22:20,880 --> 00:22:23,600 mean Simi's walking around with Wilfred's blood inside him. 335 00:22:23,600 --> 00:22:25,480 That's ridiculous. Is it? 336 00:22:27,600 --> 00:22:30,760 Bone marrow transplant. And Wilfred was the donor. 337 00:22:30,760 --> 00:22:34,560 So, Simi's blood has Wilfred's DNA. 338 00:22:42,080 --> 00:22:43,800 Do you want to come this way? Yeah. 339 00:22:48,240 --> 00:22:49,320 Just there. 340 00:22:52,400 --> 00:22:55,160 Can I get you a tea? A glass of water or...? 341 00:22:55,160 --> 00:22:57,040 Oh, no, no! 342 00:22:57,040 --> 00:22:58,080 Thanks. 343 00:23:01,040 --> 00:23:03,440 You said that Wilfred was family? 344 00:23:03,440 --> 00:23:05,200 That's right. 345 00:23:05,200 --> 00:23:06,840 Was he a close relative? 346 00:23:08,480 --> 00:23:10,800 You ask a lot of questions. 347 00:23:10,800 --> 00:23:12,480 Remember me? 348 00:23:14,280 --> 00:23:16,400 I examined you at the station. 349 00:23:16,400 --> 00:23:17,720 I saw a scar on your chest. 350 00:23:17,720 --> 00:23:19,360 That's a Hickman line scar. 351 00:23:20,960 --> 00:23:23,280 Did you have a bone marrow transplant as a kid? 352 00:23:24,720 --> 00:23:26,520 Yeah, I'm going to go. 353 00:23:26,520 --> 00:23:29,360 Simi, we found your blood at the scene of Rahul's murder. 354 00:23:31,360 --> 00:23:32,600 Did you kill him? 355 00:23:35,440 --> 00:23:40,120 No, no, no. He... He came at me! He was insane! 356 00:23:40,120 --> 00:23:41,440 It was an accident! 357 00:23:45,520 --> 00:23:47,240 I just wanted to protect Wilfred. 358 00:23:49,400 --> 00:23:52,200 Wilfred saved my life when I was a kid. 359 00:23:52,200 --> 00:23:55,240 But you know what? He could only do that because he was a match. 360 00:23:55,240 --> 00:23:58,120 People have transplants from their brothers or mothers or whatever 361 00:23:58,120 --> 00:24:01,040 because they're a match. I had no-one. 362 00:24:02,440 --> 00:24:05,520 How did you find him? There's this charity attached to our church. 363 00:24:05,520 --> 00:24:07,520 They helped us get the transplant records. 364 00:24:09,520 --> 00:24:11,240 Only it turns out Wilfred was sick. 365 00:24:12,440 --> 00:24:14,640 Were there others? Yeah. 366 00:24:14,640 --> 00:24:17,680 I mean, loads of people in his village died from the same thing. 367 00:24:19,680 --> 00:24:21,320 We found Wilfred in time. 368 00:24:23,880 --> 00:24:25,320 So we thought. 369 00:24:27,240 --> 00:24:29,400 What? 370 00:24:29,400 --> 00:24:31,120 You're not going to let me see him? 371 00:24:35,200 --> 00:24:37,920 Simi. 372 00:24:37,920 --> 00:24:39,160 There he is. 373 00:24:59,680 --> 00:25:03,120 Ah, afternoon! Present from DI Cracknell - 374 00:25:03,120 --> 00:25:05,960 all the rubbish from Simi Jacobs' address. 375 00:25:05,960 --> 00:25:07,440 Thought you might want to take a look 376 00:25:07,440 --> 00:25:09,240 in case you find anything relevant. 377 00:25:09,240 --> 00:25:13,600 Joy. Can I introduce Reverend Kanu? You've already met Jack. 378 00:25:13,600 --> 00:25:17,640 This is Dr Nikki Alexander and Dr Adam Yuen. Hello. 379 00:25:17,640 --> 00:25:21,040 Reverend Kanu runs the charitable organisation that was responsible 380 00:25:21,040 --> 00:25:22,920 for bringing Wilfred to the UK. 381 00:25:22,920 --> 00:25:24,720 I have some photos from our trip. 382 00:25:24,720 --> 00:25:28,440 Sergeant Galloway thinks they might help you. Thank you. 383 00:25:28,440 --> 00:25:30,880 I have to warn you, they're not pretty. 384 00:25:34,040 --> 00:25:36,280 Tell me how Mr Okoye came to be here. 385 00:25:37,880 --> 00:25:42,080 My church runs a charity that helps arrange treatment in the UK. 386 00:25:42,080 --> 00:25:44,880 They raise money, get doctors to volunteer, whatever. 387 00:25:46,360 --> 00:25:48,720 Wilfred's case was kind of special. 388 00:25:48,720 --> 00:25:52,400 I mean, he helped me years ago, and now he needed my help. 389 00:25:52,400 --> 00:25:54,720 The local newspaper picked up the story, it got a lot 390 00:25:54,720 --> 00:25:58,120 of publicity. So, the hospital agreed to treat him. 391 00:25:58,120 --> 00:26:00,600 And he stayed at your flat? Yeah. 392 00:26:02,840 --> 00:26:05,720 Nobody told me he don't speak English. 393 00:26:05,720 --> 00:26:08,560 I couldn't tell him anything. 394 00:26:08,560 --> 00:26:11,800 He didn't know who I was, what he did for me. 395 00:26:14,160 --> 00:26:16,960 Then I learnt that he's under the care of this Rahul guy. 396 00:26:18,800 --> 00:26:23,600 I have travelled widely in Africa as part of my ministry, 397 00:26:23,600 --> 00:26:28,480 and yet nothing could have prepared me for what we found in Bwendora. 398 00:26:31,360 --> 00:26:34,640 The town is remote, even by African standards. 399 00:26:36,120 --> 00:26:39,360 There is only very basic health care. 400 00:26:39,360 --> 00:26:42,160 It became clear there was a lot of sickness. 401 00:26:43,960 --> 00:26:46,760 This man died within hours of our arrival. 402 00:26:47,920 --> 00:26:52,360 The illness causes bleeding and rashes. Fever sometimes. 403 00:26:52,360 --> 00:26:54,520 What do the people think it's caused by? 404 00:26:54,520 --> 00:26:57,640 There's a large pesticide factory in the town. 405 00:26:57,640 --> 00:27:00,800 Many people think the water has been contaminated. 406 00:27:00,800 --> 00:27:03,760 They organised protests. 407 00:27:03,760 --> 00:27:06,720 People think there has been a cover-up. 408 00:27:06,720 --> 00:27:09,120 But the factory provides a lot of employment. 409 00:27:10,480 --> 00:27:14,200 It is a very divisive issue. 410 00:27:14,200 --> 00:27:18,920 The illness has ripped the heart out of the community. 411 00:27:18,920 --> 00:27:21,960 There are very few families it has left untouched. 412 00:27:21,960 --> 00:27:23,920 And they've had no outside help? 413 00:27:23,920 --> 00:27:27,160 There is one western charity which runs a clinic, 414 00:27:27,160 --> 00:27:29,040 but they only visit every few months. 415 00:27:31,680 --> 00:27:32,880 Some charity. 416 00:27:35,680 --> 00:27:37,840 Oh, Lord. 417 00:27:37,840 --> 00:27:39,760 Enlighten our minds with your truth. 418 00:27:42,080 --> 00:27:45,240 Give us the strength and the wisdom to seek justice. 419 00:27:46,920 --> 00:27:50,720 Shine your everlasting light into our darkness. 420 00:27:53,080 --> 00:27:56,480 There's a lot of talk about Rahul, all around the hospital. 421 00:27:56,480 --> 00:27:58,920 How the hospital is protecting him. 422 00:27:58,920 --> 00:28:02,360 How he messed up an operation and no-one wants to work with him. 423 00:28:02,360 --> 00:28:05,080 And you thought he shouldn't operate on Wilfred. 424 00:28:05,080 --> 00:28:09,080 The night before, I heard him arguing with this woman, 425 00:28:09,080 --> 00:28:11,200 Dr Braithwaite. 426 00:28:11,200 --> 00:28:13,280 She told Rahul not to do the operation 427 00:28:13,280 --> 00:28:16,080 and he just told her that she couldn't stop him. 428 00:28:16,080 --> 00:28:18,600 The bag of rubbish that we found at your home address. 429 00:28:18,600 --> 00:28:20,600 Was it from one of the offices? 430 00:28:20,600 --> 00:28:22,040 Yeah. Which one? 431 00:28:23,120 --> 00:28:24,520 All of them. 432 00:28:24,520 --> 00:28:26,960 I was looking for something, anything, 433 00:28:26,960 --> 00:28:28,800 I could use against Rahul. 434 00:28:28,800 --> 00:28:31,280 And on the morning of the operation? 435 00:28:31,280 --> 00:28:34,240 I saw Wilfred getting prepared for theatre and I panicked. 436 00:28:34,240 --> 00:28:36,000 I phoned Rahul. 437 00:28:36,000 --> 00:28:37,480 What did you say? 438 00:28:37,480 --> 00:28:39,840 I told him I had some information on him. 439 00:28:39,840 --> 00:28:43,960 I thought I could threaten to reveal what I knew if he did the operation. 440 00:28:43,960 --> 00:28:45,160 What information? 441 00:28:47,680 --> 00:28:50,760 I was bluffing. But I had to stop him. 442 00:28:53,960 --> 00:28:55,720 Well, you certainly managed that. 443 00:29:10,920 --> 00:29:12,400 How's it going? 444 00:29:12,400 --> 00:29:15,800 Oh, I'm in my element rummaging through the trash. You know me. 445 00:29:16,880 --> 00:29:19,240 Nothing much here, apart from a criminally lax attitude 446 00:29:19,240 --> 00:29:20,280 to recycling. 447 00:29:22,480 --> 00:29:24,480 Adam's still here, is he? 448 00:29:24,480 --> 00:29:26,480 We wouldn't have got this far without him. 449 00:29:26,480 --> 00:29:28,120 I want to trust him. 450 00:29:30,520 --> 00:29:31,640 What's that? 451 00:29:36,560 --> 00:29:37,600 Oh, my God. 452 00:29:39,080 --> 00:29:43,680 This was in that rubbish bag you found at Simi Jacobs' place. 453 00:29:43,680 --> 00:29:46,800 It's Harry Fletcher's ECG, taken the day of his operation. 454 00:29:46,800 --> 00:29:48,080 It's normal. 455 00:29:48,080 --> 00:29:51,920 And this is the ECG that appeared in Fletcher's notes. 456 00:29:51,920 --> 00:29:55,000 Same date and time, but grossly abnormal. 457 00:29:55,000 --> 00:29:58,800 We believe they were switched to deflect blame from Rahul 458 00:29:58,800 --> 00:30:01,160 after the operation went wrong. 459 00:30:01,160 --> 00:30:03,120 So, there was a cover-up? 460 00:30:03,120 --> 00:30:05,840 Well, what's this got to do with the murder investigation? 461 00:30:05,840 --> 00:30:08,800 Yeah, Simi Jacobs admitted to the attack on Arnie Rahul. 462 00:30:08,800 --> 00:30:11,680 I mean, he claims it was an accident as a result of self-defence. 463 00:30:11,680 --> 00:30:13,400 That fits with the crime scene findings. 464 00:30:13,400 --> 00:30:15,760 So, how does this transplant fit in? 465 00:30:15,760 --> 00:30:18,520 Well, Simi was born with sickle cell disease, 466 00:30:18,520 --> 00:30:22,680 and was treated with a bone marrow transplant at St Jude's as a child. 467 00:30:22,680 --> 00:30:25,480 Wilfred donated his stem cells for Simi's transplant. 468 00:30:25,480 --> 00:30:27,840 20 years later, Wilfred gets leukaemia. 469 00:30:27,840 --> 00:30:29,720 We don't think this is a coincidence. 470 00:30:29,720 --> 00:30:32,960 He had a type of leukaemia that can be caused by over-exposure 471 00:30:32,960 --> 00:30:34,240 to certain drugs. 472 00:30:34,240 --> 00:30:37,640 There's a technique known as mobilisation, 473 00:30:37,640 --> 00:30:40,520 which is designed to increase production of stem cells. 474 00:30:40,520 --> 00:30:44,720 Normally, stem cell donation involves giving a perfectly safe 475 00:30:44,720 --> 00:30:46,240 bone marrow stimulant. 476 00:30:46,240 --> 00:30:51,160 But whoever did this also gave Wilfred high levels of chemotherapy, 477 00:30:51,160 --> 00:30:53,000 and did so repeatedly. 478 00:30:53,000 --> 00:30:55,360 They gave chemo? To a volunteer? 479 00:30:55,360 --> 00:30:57,520 To yield even more stem cells. 480 00:30:57,520 --> 00:30:59,760 What for? More transplants? 481 00:30:59,760 --> 00:31:04,680 Stem cells have the ability to develop into any type of body cell. 482 00:31:04,680 --> 00:31:06,640 Brain, heart, blood - you name it. 483 00:31:06,640 --> 00:31:08,960 So there's a huge range of potential therapies 484 00:31:08,960 --> 00:31:12,520 in which they can be used, one of which is transplantation. 485 00:31:12,520 --> 00:31:17,200 About ten years ago, Braithwaite and her team identified stem cells 486 00:31:17,200 --> 00:31:19,400 that were very special indeed, 487 00:31:19,400 --> 00:31:22,960 capable of being turned into what are called killer T-cells, 488 00:31:22,960 --> 00:31:27,040 part of the immune system, which can be made to attack malignant tumours. 489 00:31:27,040 --> 00:31:29,400 The potential for this discovery was enormous. 490 00:31:29,400 --> 00:31:31,720 These magic cells all had the same gene, 491 00:31:31,720 --> 00:31:36,040 a gene we think might be common in Wilfred's town. 492 00:31:36,040 --> 00:31:39,840 They went looking for transplant donors to treat people like Simi, 493 00:31:39,840 --> 00:31:42,640 but what they discovered was something much bigger, 494 00:31:42,640 --> 00:31:44,760 so they went back for more, and more. 495 00:31:44,760 --> 00:31:47,400 Basically they were flogging him for every last stem cell 496 00:31:47,400 --> 00:31:49,800 he could produce. Him and all the others. 497 00:31:49,800 --> 00:31:52,120 Wilfred's town was basically a stem cell farm. 498 00:31:52,120 --> 00:31:55,560 Can you prove Wilfred was given the stimulating drugs? 499 00:31:55,560 --> 00:31:58,760 It may be possible, but that's way out of my league. 500 00:32:00,480 --> 00:32:02,360 Sounds like we need a second opinion. 501 00:32:22,360 --> 00:32:23,680 Thank you, Professor. 502 00:32:23,680 --> 00:32:25,320 Not at all. It's very good to see you. 503 00:32:25,320 --> 00:32:26,840 Thank you. Oh, he's away! 504 00:32:28,680 --> 00:32:32,120 Adam, hello again. Hello. This is Dr Nikki Alexander. 505 00:32:32,120 --> 00:32:34,480 Hello. How do you do? And you've already met DI Cracknell. 506 00:32:34,480 --> 00:32:36,080 Yes, of course. This way. 507 00:32:37,040 --> 00:32:38,720 That was Alfie. 508 00:32:38,720 --> 00:32:42,840 He's one of our early trial patients - osteosarcoma. 509 00:32:42,840 --> 00:32:44,960 When he was referred to us, he was in a hospice 510 00:32:44,960 --> 00:32:48,520 on palliative treatment, expected to die within weeks. 511 00:32:48,520 --> 00:32:50,920 Please. That was two years ago. 512 00:32:52,320 --> 00:32:53,680 He's now disease-free. 513 00:32:56,440 --> 00:32:59,920 We wanted to show you some bone marrow samples from Mr Okoye. 514 00:32:59,920 --> 00:33:02,160 He was moved from St Jude's to be treated here. 515 00:33:10,640 --> 00:33:12,600 Hmm. 516 00:33:12,600 --> 00:33:14,240 Secondary leukaemia. 517 00:33:17,120 --> 00:33:18,600 They look very unusual. 518 00:33:18,600 --> 00:33:21,440 Mr Okoye was a stem cell donor. 519 00:33:21,440 --> 00:33:23,160 Was he? 520 00:33:23,160 --> 00:33:26,400 We were wondering if it might be stimulated. 521 00:33:26,400 --> 00:33:27,760 You mean Cyclo-G? 522 00:33:29,080 --> 00:33:30,560 Oh, dear. 523 00:33:30,560 --> 00:33:34,120 Yes, it's possible. 524 00:33:34,120 --> 00:33:37,040 Is there any way we can confirm it? 525 00:33:37,040 --> 00:33:39,920 You would need to look into the genetics of his blood cells. 526 00:33:39,920 --> 00:33:42,040 There are some telltale signs. 527 00:33:42,040 --> 00:33:45,400 We have several world experts in cytogenetics here. 528 00:33:45,400 --> 00:33:47,640 They'd be happy to help. 529 00:33:47,640 --> 00:33:50,640 Your cancer therapies are based on Braithwaite's stem cell research, 530 00:33:50,640 --> 00:33:54,760 are they not? Yes. Yes. I've never denied it. 531 00:33:54,760 --> 00:33:57,440 Hers was an extraordinary piece of work. 532 00:33:58,600 --> 00:34:01,680 She tried for years to turn it into a practical treatment, 533 00:34:01,680 --> 00:34:06,280 but, in the end, she was stumped by the obvious problem. 534 00:34:06,280 --> 00:34:08,160 The limited supply of donors. 535 00:34:08,160 --> 00:34:09,440 Precisely. 536 00:34:09,440 --> 00:34:13,840 So, what we brought to the party is called gene editing. 537 00:34:15,080 --> 00:34:18,720 We found a way of inserting the special gene 538 00:34:18,720 --> 00:34:21,120 into any old stem cell, and the result is... 539 00:34:22,200 --> 00:34:23,680 Well, you met Alfie. 540 00:34:24,760 --> 00:34:27,240 What is your relationship to Emily Braithwaite? 541 00:34:28,840 --> 00:34:30,360 Yes. 542 00:34:30,360 --> 00:34:33,520 Well, I suppose you'd say we're rivals. 543 00:34:33,520 --> 00:34:37,400 She's never forgiven me for succeeding where she failed. 544 00:34:37,400 --> 00:34:41,400 But I'm afraid her star has been waning for some time. 545 00:34:41,400 --> 00:34:42,840 What makes you say that? 546 00:34:45,120 --> 00:34:47,120 She came to ask for my help. 547 00:34:47,120 --> 00:34:50,840 Believe me, that alone suggests desperation. 548 00:34:50,840 --> 00:34:54,560 She had just lost a very large research grant. 549 00:34:54,560 --> 00:34:57,120 Is it possible that Braithwaite poisoned Mr Okoye 550 00:34:57,120 --> 00:35:00,480 and everyone else in his town to get more stem cells? 551 00:35:00,480 --> 00:35:03,200 That's a serious accusation. 552 00:35:03,200 --> 00:35:05,040 Everything's falling apart. 553 00:35:05,040 --> 00:35:07,440 So, like a gambler, she risks more and more, 554 00:35:07,440 --> 00:35:10,120 desperate for that big win to get herself back on top. 555 00:35:20,000 --> 00:35:25,600 THEY CONFER 556 00:35:28,760 --> 00:35:30,400 PHONE PINGS 557 00:36:05,600 --> 00:36:07,200 Now what? Excuse me? 558 00:36:08,360 --> 00:36:11,600 You do realise my career is over? And that's my fault? 559 00:36:11,600 --> 00:36:13,480 There's got to be a way out of this. 560 00:36:13,480 --> 00:36:14,800 You owe me that at least. 561 00:36:16,080 --> 00:36:18,720 You want Auntie Emily to make it better? 562 00:36:20,240 --> 00:36:24,440 All those years I stuck up for you with your father. 563 00:36:24,440 --> 00:36:27,360 You messed up. Again. 564 00:36:27,360 --> 00:36:29,120 For once in your life, own it. 565 00:36:31,400 --> 00:36:33,000 I don't get it. 566 00:36:33,000 --> 00:36:34,520 You and Rahul. 567 00:36:34,520 --> 00:36:36,720 You go to all these lengths to protect his reputation, 568 00:36:36,720 --> 00:36:39,480 yet you show no interest in who might have killed him. 569 00:36:39,480 --> 00:36:41,840 You don't even seem to even care that he's dead! 570 00:36:43,240 --> 00:36:45,800 Maybe I've learnt to bury my emotions. 571 00:36:47,640 --> 00:36:48,840 You should try it. 572 00:36:50,760 --> 00:36:52,840 You know they're onto you, 573 00:36:52,840 --> 00:36:55,560 and I'm not going to help you this time. 574 00:36:55,560 --> 00:36:56,840 Oh, please. 575 00:36:58,440 --> 00:36:59,880 This is so painful. 576 00:37:06,640 --> 00:37:09,080 So, all roads lead to Braithwaite. 577 00:37:09,080 --> 00:37:11,400 Yes, but it's all circumstantial. 578 00:37:11,400 --> 00:37:14,080 There's nothing directly connecting her to Wilfred. 579 00:37:14,080 --> 00:37:16,440 If you can find me something concrete, I'll bring her in, 580 00:37:16,440 --> 00:37:18,360 but until then, it's just speculation. 581 00:37:18,360 --> 00:37:20,760 Adam, where did you get to? 582 00:37:20,760 --> 00:37:23,320 Rahul's conduct during Fletcher's operation amounted to 583 00:37:23,320 --> 00:37:25,280 criminal negligence. 584 00:37:25,280 --> 00:37:27,360 He could have been charged for manslaughter. 585 00:37:27,360 --> 00:37:28,720 Well, he's dead. 586 00:37:28,720 --> 00:37:30,680 What if Braithwaite covered it up? 587 00:37:30,680 --> 00:37:33,080 That's attempting to pervert the course of justice. 588 00:37:33,080 --> 00:37:34,600 Which means you can arrest her. 589 00:37:34,600 --> 00:37:37,680 Oh, and how do we know that Braithwaite swaps the ECG? 590 00:37:37,680 --> 00:37:40,080 We can't. There are several sets of prints on the trace, 591 00:37:40,080 --> 00:37:41,680 one of which could be Braithwaite's. 592 00:37:41,680 --> 00:37:44,120 Exactly, so we can't just arrest her on the off-chance that 593 00:37:44,120 --> 00:37:45,560 her prints are on there. I know. 594 00:37:45,560 --> 00:37:47,040 ADAM: I met her for a drink. 595 00:37:51,000 --> 00:37:52,760 Her prints are on this glass. 596 00:37:52,760 --> 00:37:56,000 When you find that they are the same as the sets on the ECG, 597 00:37:56,000 --> 00:37:58,760 then you can arrest her. That's not admissible as evidence! 598 00:37:58,760 --> 00:38:00,400 It doesn't have to be. 599 00:38:01,920 --> 00:38:05,320 How do we know for sure she touched this glass? 600 00:38:05,320 --> 00:38:07,520 Well, you're just going to have to trust me. 601 00:38:54,160 --> 00:38:55,640 You two go round the back. 602 00:38:59,600 --> 00:39:01,080 DOORBELL RINGS 603 00:39:07,280 --> 00:39:09,360 Her car's here. Looks like she's home. 604 00:39:12,440 --> 00:39:13,480 No letterbox. 605 00:39:17,960 --> 00:39:19,320 Dr Braithwaite? 606 00:39:20,320 --> 00:39:22,680 DS Galloway. Could you open the door, please? 607 00:39:27,040 --> 00:39:29,160 Police! Dr Braithwaite? 608 00:39:41,280 --> 00:39:42,360 Shit. 609 00:39:48,640 --> 00:39:50,280 No sign of external injury. 610 00:39:52,120 --> 00:39:55,520 Both front and back doors were locked from the inside. 611 00:39:55,520 --> 00:39:58,120 There's no signs of forced entry. 612 00:39:58,120 --> 00:39:59,640 Everything's neat and tidy. 613 00:40:01,800 --> 00:40:03,160 Sudden chest pain, maybe? 614 00:40:04,680 --> 00:40:05,720 Or suicide. 615 00:40:38,160 --> 00:40:41,040 Nikki. Adam. Look at these. 616 00:40:46,560 --> 00:40:49,760 Two samples with Wilfred Okoye's name on. 617 00:41:12,760 --> 00:41:14,720 Look at this. 618 00:41:14,720 --> 00:41:17,000 The boiler's locked out. 619 00:41:17,000 --> 00:41:18,920 Yeah. Mine does that all the time. 620 00:41:18,920 --> 00:41:20,160 Bloody things. 621 00:41:58,560 --> 00:42:01,120 Heart weighs 380g. 622 00:42:27,280 --> 00:42:30,120 Evidence of left ventricular hypertrophy. 623 00:42:31,480 --> 00:42:32,960 Valves unremarkable. 624 00:42:36,280 --> 00:42:40,120 Left anterior descending coronary artery. 625 00:42:40,120 --> 00:42:43,160 Moderate stenosis, no evidence of thrombus. 626 00:42:51,560 --> 00:42:54,200 The toxicology was entirely negative, 627 00:42:54,200 --> 00:42:56,760 apart from a modest level of alcohol. 628 00:42:56,760 --> 00:43:00,720 No paracetamol, no benzodiazepines, nothing. 629 00:43:00,720 --> 00:43:04,320 So this, together with the absence of pills and containers 630 00:43:04,320 --> 00:43:07,280 at the address, and the absence of any needle marks on the body, 631 00:43:07,280 --> 00:43:10,440 leads me to conclude that death was not as a result 632 00:43:10,440 --> 00:43:13,000 of suicide or poisoning. 633 00:43:13,000 --> 00:43:16,480 In fact, the only significant finding from the postmortem 634 00:43:16,480 --> 00:43:19,440 examination is moderate ischaemic heart disease, 635 00:43:19,440 --> 00:43:22,880 together with hypertrophy of the septum and left ventricular wall. 636 00:43:22,880 --> 00:43:25,840 But no evidence of coronary thrombosis? 637 00:43:25,840 --> 00:43:28,800 The ventricular wall thickness... Heart attack. ..and the degree 638 00:43:28,800 --> 00:43:32,600 of myocardial disarray on microscopy are borderline 639 00:43:32,600 --> 00:43:34,640 for a diagnosis of HCM. 640 00:43:34,640 --> 00:43:37,560 What's that? Hypertrophic cardiomyopathy. 641 00:43:37,560 --> 00:43:40,920 It's an inherited heart condition that can lead to sudden death. 642 00:43:40,920 --> 00:43:42,800 Fabrice Muamba. Yes. 643 00:43:44,720 --> 00:43:48,440 Bolton Wanderers versus Tottenham. FA Cup quarterfinal, 2012. 644 00:43:48,440 --> 00:43:50,400 He collapsed on the pitch. Nearly died. 645 00:43:50,400 --> 00:43:52,280 Well, technically he did. 646 00:43:52,280 --> 00:43:54,320 In cases of high stress or exercise, 647 00:43:54,320 --> 00:43:58,440 the heart can lead into an abnormal rhythm, which can be fatal. 648 00:43:58,440 --> 00:44:01,360 And Emily Braithwaite was under a lot of stress. 649 00:44:01,360 --> 00:44:05,840 So it is possible that this caused a dysrhythmic event... 650 00:44:05,840 --> 00:44:08,640 Heart attack. ..that led to her death, don't you think? 651 00:44:12,640 --> 00:44:14,640 How come she didn't have a letterbox? 652 00:44:14,640 --> 00:44:17,000 It's a passive house. It's so well-insulated, 653 00:44:17,000 --> 00:44:19,680 it doesn't need heating. You heat it up just by living in it. 654 00:44:19,680 --> 00:44:21,440 But it has to be really airtight. 655 00:44:21,440 --> 00:44:23,560 It's like living in a bubble. 656 00:44:23,560 --> 00:44:26,760 All the air goes in and out through a single ventilation system. 657 00:44:28,400 --> 00:44:31,320 But why would the boiler lock out? 658 00:44:31,320 --> 00:44:35,760 What if it was faulty and produced a lot of carbon monoxide? 659 00:44:35,760 --> 00:44:38,120 No carbon monoxide in the toxicology. 660 00:44:42,400 --> 00:44:45,000 She's a suspect in a murder case. She conveniently dies. 661 00:44:45,000 --> 00:44:46,840 What if others were involved? 662 00:44:46,840 --> 00:44:48,960 If you can tell me how they did it, I'll believe you, 663 00:44:48,960 --> 00:44:52,480 but until then, it's looking like natural causes. 664 00:44:52,480 --> 00:44:56,040 Right, then, provisional assumption is that Braithwaite 665 00:44:56,040 --> 00:44:58,760 was guilty of conspiracy to murder Wilfred Okoye, 666 00:44:58,760 --> 00:45:01,720 as well as perverting the course of justice in the Fletcher case. 667 00:45:01,720 --> 00:45:02,920 What about Simi? 668 00:45:02,920 --> 00:45:06,960 That's up to the CPS, whether they buy a self-defence plea. 669 00:45:06,960 --> 00:45:08,480 I'll keep you posted. 670 00:45:26,480 --> 00:45:28,760 So this is where you've been hiding. 671 00:45:30,960 --> 00:45:32,760 Adam told you, then? 672 00:45:32,760 --> 00:45:35,280 Oh, yeah. He told me everything. 673 00:46:31,680 --> 00:46:33,080 I don't get it. 674 00:46:33,080 --> 00:46:36,080 How could someone like Braithwaite justify it to herself, 675 00:46:36,080 --> 00:46:37,400 let alone anyone else? 676 00:46:37,400 --> 00:46:39,920 They get fixated on the prize, don't they? 677 00:46:39,920 --> 00:46:43,480 The breakthrough, and all the acclaim that goes with it. Mm. 678 00:46:44,600 --> 00:46:47,800 Did you ever want to do something like that? Fancy research job? 679 00:46:48,800 --> 00:46:50,640 I think you'd be really good at that. 680 00:46:53,560 --> 00:46:54,600 I don't know. 681 00:46:55,720 --> 00:46:57,600 It's more Adam's world. Mm. 682 00:46:58,760 --> 00:46:59,960 Not any more. 683 00:47:01,640 --> 00:47:04,400 You can see how liberated he's been. 684 00:47:04,400 --> 00:47:07,480 He's carried that secret around for so long. 685 00:47:07,480 --> 00:47:11,040 Well, he's stopped trying to be all things to all men. 686 00:47:11,040 --> 00:47:13,960 And I'll tell you, he loves beating himself up. 687 00:48:13,400 --> 00:48:16,920 Hi. I'm working on the case of Wilfred Okoye. 688 00:48:16,920 --> 00:48:19,200 I was wondering if I could get his microbiology results 689 00:48:19,200 --> 00:48:20,640 from his stay here. 690 00:48:20,640 --> 00:48:23,120 Date of birth is 9/7/66. 691 00:48:28,440 --> 00:48:31,040 I just need to, er, speak to my supervisor. 692 00:48:31,040 --> 00:48:32,280 OK. Thank you. 693 00:49:10,160 --> 00:49:11,960 PHONE PINGS 694 00:49:11,960 --> 00:49:13,520 It's Adam. 695 00:49:15,720 --> 00:49:17,320 "We were wrong about everything. 696 00:49:19,400 --> 00:49:22,040 "At Cowley Institute. Come quickly." What? 697 00:49:25,440 --> 00:49:27,320 What are we looking at? 698 00:49:27,320 --> 00:49:30,160 Wilfred's blood cultures. Microbiology report. 699 00:49:33,000 --> 00:49:34,240 Hang on. 700 00:49:35,560 --> 00:49:39,280 The antibiotic sensitivities have been reversed. 701 00:49:39,280 --> 00:49:40,760 Who's done that? Braithwaite? 702 00:49:40,760 --> 00:49:43,320 Couldn't be. These are from the Cowley institute. 703 00:49:45,960 --> 00:49:47,560 Adam needs us. Come on. 704 00:50:17,200 --> 00:50:18,600 SHE SIGHS 705 00:50:18,600 --> 00:50:21,440 Oh, great. We were supposed to go left back at the lights. 706 00:50:35,720 --> 00:50:37,160 CAR DOOR OPENS 707 00:50:38,800 --> 00:50:39,920 Dr Yuen? 708 00:50:39,920 --> 00:50:43,120 You know Emily Braithwaite died yesterday? 709 00:50:43,120 --> 00:50:47,360 What? Uh, no. How did it happen? 710 00:50:47,360 --> 00:50:50,520 Unknown. Found dead in a house that was bolted from the inside. 711 00:50:52,040 --> 00:50:54,600 Oh, look, an oxygen analyser. 712 00:50:56,000 --> 00:50:57,880 Do you always keep one of those in your car? 713 00:50:57,880 --> 00:50:59,720 I use it for various things. 714 00:50:59,720 --> 00:51:03,000 So Emily died just as you convinced us she was guilty. 715 00:51:03,000 --> 00:51:05,720 Her work was based on exploitation. 716 00:51:05,720 --> 00:51:07,920 Well, she can't deny that now, can she? 717 00:51:07,920 --> 00:51:09,280 Well, whatever happened, 718 00:51:09,280 --> 00:51:12,560 I'm sure forensic science will find the answer. 719 00:51:12,560 --> 00:51:16,040 Mm. Then I realised just how much liquid nitrogen you go through here. 720 00:51:16,040 --> 00:51:18,040 Two deliveries in three days? 721 00:51:20,200 --> 00:51:23,600 I mean, that is some evil genius stuff. 722 00:51:23,600 --> 00:51:25,760 Pretty quick and very clean. 723 00:51:25,760 --> 00:51:29,360 Except the pilot light in the boiler went out at Braithwaite's house. 724 00:51:29,360 --> 00:51:30,760 Otherwise, the perfect crime. 725 00:51:32,000 --> 00:51:33,400 Are you insane? 726 00:51:33,400 --> 00:51:36,440 Oh, sorry. That's forensic science. Get out. 727 00:51:40,720 --> 00:51:43,400 Braithwaite had Wilfred's blood samples. She was onto you. 728 00:51:44,680 --> 00:51:46,480 My research is changing lives. 729 00:51:46,480 --> 00:51:48,200 She never made the crucial breakthrough, 730 00:51:48,200 --> 00:51:49,760 but then again, neither did you. 731 00:51:49,760 --> 00:51:51,920 You reckon you'll crack it any minute now, don't you? 732 00:51:51,920 --> 00:51:54,400 You just have to keep going, keep blasting innocent men 733 00:51:54,400 --> 00:51:56,880 and women with poisonous drugs, and then you'll get there. 734 00:51:56,880 --> 00:51:59,640 You know nothing. There's no gene editing going on here. 735 00:51:59,640 --> 00:52:02,080 Your magic treatments are all from stem cells that you get 736 00:52:02,080 --> 00:52:03,560 from killing people like Wilfred. 737 00:52:03,560 --> 00:52:07,240 When childhood cancer is a thing of the past thanks to me, 738 00:52:07,240 --> 00:52:09,520 no-one will care. 739 00:52:09,520 --> 00:52:12,080 That's what it's all about, isn't it? 740 00:52:12,080 --> 00:52:16,560 It's not about the money or the power. It's about the prestige. 741 00:52:18,200 --> 00:52:20,800 So what are you going to do about it, Adam? 742 00:52:20,800 --> 00:52:22,800 Mm? You're discredited. 743 00:52:22,800 --> 00:52:24,240 You're getting struck off. 744 00:52:25,480 --> 00:52:28,120 Of course I know! 745 00:52:28,120 --> 00:52:29,280 I know everything. 746 00:52:31,840 --> 00:52:34,240 You've no idea who you're dealing with. 747 00:52:36,680 --> 00:52:37,920 Adam? 748 00:52:40,160 --> 00:52:41,200 Adam! 749 00:52:43,560 --> 00:52:47,120 PHONE RINGS 750 00:52:47,120 --> 00:52:49,640 Adam? What's happening? 751 00:52:49,640 --> 00:52:53,040 Cowley's the one exploiting Wilfred and the rest of the donors. 752 00:52:53,040 --> 00:52:55,240 And he killed Braithwaite with liquid nitrogen. 753 00:52:55,240 --> 00:52:57,360 He poured it in the vent of her airtight house, 754 00:52:57,360 --> 00:53:00,840 turning it into a gas chamber. She suffocated. 755 00:53:00,840 --> 00:53:03,840 Cowley did a deal with Rahul to kill Wilfred during surgery. 756 00:53:03,840 --> 00:53:06,760 And when that failed, he attacked Wilfred with the bacteria... 757 00:53:09,080 --> 00:53:11,320 ..to make sure he switched the micro reports 758 00:53:11,320 --> 00:53:13,320 so that the antibiotics wouldn't work. 759 00:53:13,320 --> 00:53:15,200 ENGINE REVS 760 00:53:26,640 --> 00:53:27,840 Adam? 761 00:53:29,080 --> 00:53:30,400 Adam! 762 00:53:40,000 --> 00:53:41,440 HE COUGHS 763 00:53:49,920 --> 00:53:53,720 I'm sure that's Cowley. Really? Call Cracknell. 764 00:53:53,720 --> 00:53:55,920 But... Get after him. I'll find Adam. 765 00:54:04,520 --> 00:54:08,520 Yeah, I'm heading north on Colbridge Road. 766 00:54:08,520 --> 00:54:11,280 It's a black Mercedes. 767 00:54:11,280 --> 00:54:12,640 Adam? 768 00:54:12,640 --> 00:54:13,760 Adam! 769 00:54:13,760 --> 00:54:15,120 Oh, Jesus. 770 00:54:18,480 --> 00:54:20,000 Ambulance. 771 00:54:20,000 --> 00:54:23,240 SIRENS WAIL 772 00:54:26,120 --> 00:54:28,360 Can you hear me? Adam? 773 00:54:28,360 --> 00:54:30,880 You took your time, mate. 774 00:54:30,880 --> 00:54:32,280 Come to take all the credit? 775 00:54:34,120 --> 00:54:35,400 Oh, man. 776 00:54:36,880 --> 00:54:39,600 The ambulance is on its way. What happened? 777 00:54:39,600 --> 00:54:40,840 I messed up. 778 00:54:56,960 --> 00:54:58,120 You trusted me. 779 00:55:01,880 --> 00:55:02,960 That means a lot. 780 00:55:05,000 --> 00:55:07,480 Adam. Adam, stay with me. 781 00:55:07,480 --> 00:55:09,800 Adam. Come on, man. Stay with me. Stay with me. 782 00:55:09,800 --> 00:55:11,080 Come on! Adam! 783 00:55:12,360 --> 00:55:13,400 Adam! 784 00:55:31,640 --> 00:55:35,440 SIREN WAILS 785 00:56:00,480 --> 00:56:01,520 Oh, God. 786 00:56:08,600 --> 00:56:10,000 Oh, no. 787 00:56:14,520 --> 00:56:18,240 SHE SOBS 788 00:56:42,120 --> 00:56:48,480 Testator silens 789 00:56:51,320 --> 00:56:58,120 Costestes e spiritu 790 00:56:58,120 --> 00:57:04,600 Silencium. 791 00:57:04,650 --> 00:57:09,200 Repair and Synchronization by Easy Subtitles Synchronizer 1.0.0.0 61286

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